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https://www.readbyqxmd.com/read/28521267/epileptogenic-high-frequency-oscillations-skip-the-motor-area-in-children-with-multilobar-drug-resistant-epilepsy
#1
Yasushi Iimura, Kevin Jones, Kyoko Hattori, Yushi Okazawa, Atsuko Noda, Kana Hoashi, Yutaka Nonoda, Eishi Asano, Tomoyuki Akiyama, Cristina Go, Ayako Ochi, O Carter Snead, Elizabeth J Donner, James T Rutka, James M Drake, Hiroshi Otsubo
OBJECTIVE: Subtotal hemispherectomy involves the resection of multiple lobes in children with drug-resistant epilepsy, skipping the motor area (MA). We determined epileptogenicity using the occurrence rate (OR) of high-frequency oscillations (HFOs) and the modulation index (MI), demonstrating strength of coupling between HFO and slow wave. We hypothesized that epileptogenicity increased over the multiple lobes but skipped the MA. METHODS: We analyzed 23 children (14 subtotal hemispherectomy; 9 multilobar resections)...
March 24, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28499085/simultaneous-oxidation-and-sequestration-of-as-iii-from-water-by-using-redox-polymer-based-fe-iii-oxide-nanocomposite
#2
Xiaolin Zhang, Mengfei Wu, Hao Dong, Hongchao Li, Bing-Cai Pan
Water decontamination from As(III) is an urgent but still challenging task. Herein, we fabricated a bifunctional nanocomposite HFO@PS-Cl for highly efficient removal of As(III), with active chlorine covalently binding spherical polystyrene host for in situ oxidation of As(III) to As(V), and Fe(III) hydroxide (HFO) nanoparticles (NPs) embedded inside for specific As(V) removal. HFO@PS-Cl could work effectively in a wide pH range (5-9), and other ubiquitous anions like sulfate, chloride, bicarbonate, and silicate exert insignificant effect on As(III) removal...
May 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28463818/high-frequency-somatosensory-stimulation-increases-sensori-motor-inhibition-and-leads-to-perceptual-improvement-in-healthy-subjects
#3
Lorenzo Rocchi, Roberto Erro, Elena Antelmi, Alfredo Berardelli, Michele Tinazzi, Rocco Liguori, Kailash Bhatia, John Rothwell
OBJECTIVE: High frequency repetitive somatosensory stimulation (HF-RSS), which is a patterned electric stimulation applied to the skin through surface electrodes, improves two-point discrimination, somatosensory temporal discrimination threshold (STDT) and motor performance in humans. However, the mechanisms which underlie these changes are still unknown. In particular, we hypothesize that refinement of inhibition might be responsible for the improvement in spatial and temporal perception...
June 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28451519/a-longitudinal-ecological-study-of-household-firearm-ownership-and-firearm-related-deaths-in-the-united-states-from-1999-through-2014-a-specific-focus-on-gender-race-and-geographic-variables
#4
David A Geier, Janet K Kern, Mark R Geier
Firearms have a longstanding tradition in the United States (US) and are viewed by many with iconic stature with regards to safety and personal freedom. Unfortunately, from a public health point of view, firearm-related deaths (FRDs) in the US have reached a crisis point with an estimated > 31,000 deaths and 74,000 nonfatal injuries resulting from firearms each year. This longitudinal ecological study analyzed variations in FRDs following firearm assaults (FAs) and law enforcement incidents involving a firearm (LEIF) in comparison to variations in household firearm ownership (HFO) among different geographic and demographic groups in the US from 1999 to 2014...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28450702/complement-factors-c4-and-c3-are-down-regulated-in-response-to-short-term-overfeeding-in-healthy-young-men
#5
Caroline Foghmar, Charlotte Brøns, Katrine Pilely, Allan Vaag, Peter Garred
Insulin resistance is associated with high circulating level of complement factor C3. Animal studies suggest that improper complement activation mediates high-fat-diet-induced insulin resistance. Individuals born with low birth weight (LBW) are at increased risk of developing insulin resistance. We hypothesized that high-fat overfeeding (HFO) increase circulating C3 and induce complement activation in a birth weight differential manner. Twenty LBW and 26 normal birth weight (NBW) young men were studied using a randomised crossover design...
April 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28432891/modification-of-an-existing-in%C3%A2-vitro-method-to-predict-relative-bioavailable-arsenic-in-soils
#6
Shane Whitacre, Nicholas Basta, Brooke Stevens, Valerie Hanley, Richard Anderson, Kirk Scheckel
The soil matrix can sequester arsenic (As) and reduces its exposure by soil ingestion. In vivo dosing studies and in vitro gastrointestinal (IVG) methods have been used to predict relative bioavailable (RBA) As. Originally, the Ohio State University (OSU-IVG) method predicted RBA As for soils exclusively from mining and smelting sites with a median of 5,636 mg As kg(-1). The objectives of the current study were to (i) evaluate the ability of the OSU-IVG method to predict RBA As for As contaminated soils with a wider range of As content and As contaminant sources, and (ii) evaluate a modified extraction procedure's ability to improve prediction of RBA As...
April 3, 2017: Chemosphere
https://www.readbyqxmd.com/read/28406919/what-are-the-assets-and-weaknesses-of-hfo-detectors-a-benchmark-framework-based-on-realistic-simulations
#7
Nicolas Roehri, Francesca Pizzo, Fabrice Bartolomei, Fabrice Wendling, Christian-George Bénar
High-frequency oscillations (HFO) have been suggested as biomarkers of epileptic tissues. While visual marking of these short and small oscillations is tedious and time-consuming, automatic HFO detectors have not yet met a large consensus. Even though detectors have been shown to perform well when validated against visual marking, the large number of false detections due to their lack of robustness hinder their clinical application. In this study, we developed a validation framework based on realistic and controlled simulations to quantify precisely the assets and weaknesses of current detectors...
2017: PloS One
https://www.readbyqxmd.com/read/28337411/physiological-and-pathological-high-frequency-oscillations-have-distinct-sleep-homeostatic-properties
#8
Nicolás von Ellenrieder, François Dubeau, Jean Gotman, Birgit Frauscher
OBJECTIVE: The stage of sleep is a known modulator of high-frequency oscillations (HFOs). For instance, high amplitude slow waves during NREM sleep and the subtypes of REM sleep were shown to contribute to a better separation between physiological and pathological HFOs. This study investigated rates and spatial spread of the different HFO types (physiological and pathological ripples in the 80-250 Hz frequency band, and fast ripples above 250 Hz) depending on time spent in sleep across the different sleep cycles...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28291015/single-layer-of-ge-quantum-dots-in-hfo2-for-floating-gate-memory-capacitors
#9
A M Lepadatu, C Palade, A Slav, A V Maraloiu, S Lazanu, T Stoica, C Logofatu, V S Teodorescu, M L Ciurea
High performance trilayer memory capacitors with a floating gate of a single layer of Ge quantum dots (QDs) in HfO2 were fabricated using magnetron sputtering followed by rapid thermal annealing (RTA). The layer sequence of the capacitors is gate HfO 2/floating gate of single layer of Ge QDs in HfO 2/tunnel HfO 2/p-Si wafers. Both Ge and HfO2 are nanostructured by RTA at moderate temperatures of 600-700 °C. By nanostructuring at 600 °C, the formation of a single layer of well separated Ge QDs with diameters of 2-3 nm at a density of 4-5 × 10(15) m(-2) is achieved in the floating gate (intermediate layer)...
April 28, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28281660/dpp-4-inhibitor-and-estrogen-share-similar-efficacy-against-cardiac-ischemic-reperfusion-injury-in-obese-insulin-resistant-and-estrogen-deprived-female-rats
#10
Sivaporn Sivasinprasasn, Pongpan Tanajak, Wanpitak Pongkan, Wasana Pratchayasakul, Siriporn C Chattipakorn, Nipon Chattipakorn
Estrogen deprivation aggravates cardiac injury after myocardial ischemia and reperfusion (I/R) injury. Although either estrogen or the dipeptidyl peptidase-4 (DPP-4) inhibitor, vildagliptin, reduces myocardial damage following cardiac I/R, their effects on the heart in obese-insulin resistant and estrogen deprived conditions remain unknown. Ovariectomized (O) rats (n = 36) were divided to receive either normal diet (NDO) or high-fat diet (HFO) for 12 weeks, followed by treatment with a vehicle, estrogen or vildagliptin for 4 weeks...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28268496/computational-modeling-of-high-frequency-oscillations-recorded-with-clinical-intracranial-macroelectrodes
#11
M Shamas, P Benquet, I Merlet, W El Falou, M Khalil, F Wendling
High Frequency Oscillations (HFOs) are a potential biomarker of epileptogenic regions. They have been extensively investigated in terms of automatic detection, classification and feature extraction. However, the mechanisms governing the generation of HFOs as well as the observability conditions on clinical intracranial macroelectrodes remain elusive. In this paper, we propose a novel physiologically-relevant macroscopic model for accurate simulation of HFOs as invasively recorded in epileptic patients. This model accounts for both the temporal and spatial properties of the cortical patch at the origin of epileptiform activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268481/multi-channel-algorithms-for-epileptic-high-frequency-oscillation-detection
#12
Chen-Wei Chou, Chien Chen, Shang-Yeong Kwan, Shun-Chi Wu
Short-lasting rhythmic activity in intracranial electroencephalogram (iEEG) in the frequency range of 80 to 500 Hz is regarded to be a promising biomarker of epileptogenicity. This activity is referred to as high-frequency oscillation (HFO), and its detection from iEEG is considered the first step to several applications. In this study, several multi-channel algorithms for HFO detection are proposed. With the proposed multi-channel statistics and threshold determination scheme, the algorithms allow HFO detection to be performed without breaking the iEEG channel structure and the detection threshold to be determined automatically...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28256273/direct-resin-composite-restorations-for-fractured-maxillary-teeth-and-diastema-closure-a-7-years-retrospective-evaluation-of-survival-and-influencing-factors
#13
Edina Lempel, Bálint Viktor Lovász, Réka Meszarics, Sára Jeges, Ákos Tóth, József Szalma
OBJECTIVES: This retrospective study evaluated the survival rate of anterior direct resin based composite (RBC) build-ups in vital teeth made of microhybrid and nanofill RBC materials and the influence of bruxism, beverage consumption and smoking on the long-term performance of restorations. METHODS: Patients receiving anterior restoration between 2006 and 2011, with the diagnosis of fracture or diastema, were selected. A total of 65 adult patients (mean age: 25...
April 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28235667/automated-detection-of-high-frequency-oscillations-in-electrophysiological-signals-methodological-advances
#14
Miguel Navarrete, Jan Pyrzowski, Juliana Corlier, Mario Valderrama, Michel Le Van Quyen
In recent years, new recording technologies have advanced such that oscillations of neuronal networks can be identified from simultaneous, multisite recordings at high temporal and spatial resolutions. However, because of the deluge of multichannel data generated by these experiments, achieving the full potential of parallel neuronal recordings also depends on the development of new mathematical methods capable of extracting meaningful information related to time, frequency and space. In this review, we aim to bridge this gap by focusing on the new analysis tools developed for the automated detection of high-frequency oscillations (HFOs, > 40 Hz) in local field potentials...
February 21, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28226670/computational-modeling-of-high-frequency-oscillations-recorded-with-clinical-intracranial-macroelectrodes
#15
M Shamas, P Benquet, I Merlet, W El Falou, M Khalil, F Wendling, M Shamas, P Benquet, I Merlet, W El Falou, M Khalil, F Wendling, M Khalil, P Benquet, I Merlet, W El Falou, M Shamas, F Wendling
High Frequency Oscillations (HFOs) are a potential biomarker of epileptogenic regions. They have been extensively investigated in terms of automatic detection, classification and feature extraction. However, the mechanisms governing the generation of HFOs as well as the observability conditions on clinical intracranial macroelectrodes remain elusive. In this paper, we propose a novel physiologically-relevant macroscopic model for accurate simulation of HFOs as invasively recorded in epileptic patients. This model accounts for both the temporal and spatial properties of the cortical patch at the origin of epileptiform activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226654/multi-channel-algorithms-for-epileptic-high-frequency-oscillation-detection
#16
Chen-Wei Chou, Chien Chen, Shang-Yeong Kwan, Shun-Chi Wu, Chen-Wei Chou, Chien Chen, Shang-Yeong Kwan, Shun-Chi Wu, Chien Chen, Chen-Wei Chou, Shun-Chi Wu, Shang-Yeong Kwan
Short-lasting rhythmic activity in intracranial electroencephalogram (iEEG) in the frequency range of 80 to 500 Hz is regarded to be a promising biomarker of epileptogenicity. This activity is referred to as high-frequency oscillation (HFO), and its detection from iEEG is considered the first step to several applications. In this study, several multi-channel algorithms for HFO detection are proposed. With the proposed multi-channel statistics and threshold determination scheme, the algorithms allow HFO detection to be performed without breaking the iEEG channel structure and the detection threshold to be determined automatically...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28176491/cells-responding-to-surface-structure-of-calcium-phosphate-ceramics-for-bone-regeneration
#17
Jingwei Zhang, Lanying Sun, Xiaoman Luo, Davide Barbieri, Joost D de Bruijn, Clemens A van Blitterswijk, Lorenzo Moroni, Huipin Yuan
Surface structure largely affects the inductive bone-forming potential of calcium phosphate (CaP) ceramics in ectopic sites and bone regeneration in critical-sized bone defects. Surface-dependent osteogenic differentiation of bone marrow stromal cells (BMSCs) partially explained the improved bone-forming ability of submicron surface structured CaP ceramics. In this study, we investigated the possible influence of surface structure on different bone-related cells, which may potentially participate in the process of improved bone formation in CaP ceramics...
February 8, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28160749/interrater-reliability-of-visually-evaluated-high-frequency-oscillations
#18
Aaron M Spring, Daniel J Pittman, Yahya Aghakhani, Jeffrey Jirsch, Neelan Pillay, Luis E Bello-Espinosa, Colin Josephson, Paolo Federico
OBJECTIVE: High frequency oscillations (HFOs) and interictal epileptiform discharges (IEDs) have been shown to be markers of epileptogenic regions. However, there is currently no 'gold standard' for identifying HFOs. Accordingly, we aimed to formally characterize the interrater reliability of HFO markings to validate the current practices. METHODS: A morphology detector was implemented to detect events (candidate HFOs, lower-threshold events, and distractors) from the intracranial EEG (iEEG) of ten patients...
December 30, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28158072/influence-of-coating-thickness-on-laser-induced-damage-characteristics-of-anti-reflection-coatings-irradiated-by-1064%C3%A2-%C3%A2-nm-nanosecond-laser-pulses
#19
Zhi Song, Xinbin Cheng, Hongping Ma, Jinlong Zhang, Bin Ma, Hongfei Jiao, Zhanshan Wang
The influence of coating thickness on laser-induced damage (LID) characteristics of anti-reflection (AR) coatings irradiated by 1064 nm nanosecond laser pulses was investigated. Two HfO<sub>2</sub>/SiO<sub>2</sub> AR coatings with different physical thicknesses, 0.7 and 2.7 μm, were prepared and tested. To study the effect of coating thickness on a laser-induced damage threshold (LIDT) in isolation, electric field intensities (EFIs) at the substrate-coating interface were kept the same by using proper AR designs...
February 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/28158069/strategies-to-increase-laser-damage-performance-of-ta-sub-2-sub-o-sub-5-sub-sio-sub-2-sub-mirrors-by-modifications-of-the-top-layer-design
#20
Drew Schiltz, Dinesh Patel, Cory Baumgarten, Brendan A Reagan, Jorge J Rocca, Carmen S Menoni
Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub> high reflection (HR) interference coatings for λ∼1  μm offer superior performance at high irradiance conditions. However, these coatings are not good candidates for high peak power conditions in comparison to HfO<sub>2</sub>/SiO<sub>2</sub> multilayer stacks. Here we show that the modification of the top layers design of a quarter wave Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub> high reflector leads to 4-5 fold increase in the laser damage fluence compared to a quarter wave (Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub>)<sup>15</sup> when tested at λ=1...
February 1, 2017: Applied Optics
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