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Jingwei Zhang, Lanying Sun, Xiaoman Luo, Davide Barbieri, Joost D de Bruijn, Clemens A van Blitterswijk, Lorenzo Moroni, Huipin Yuan
Surface structure largely affects the inductive bone-forming potential of calcium phosphate (CaP) ceramics in ectopic sites and bone regeneration in critical-sized bone defects. Surface-dependent osteogenic differentiation of bone marrow stromal cells (BMSCs) partially explained the improved bone-forming ability of submicron surface structured CaP ceramics. In this study, we investigated the possible influence of surface structure on different bone-related cells, which may potentially participate in the process of improved bone formation in CaP ceramics...
February 8, 2017: Journal of Tissue Engineering and Regenerative Medicine
Aaron M Spring, Daniel J Pittman, Yahya Aghakhani, Jeffrey Jirsch, Neelan Pillay, Luis E Bello-Espinosa, Colin Josephson, Paolo Federico
OBJECTIVE: High frequency oscillations (HFOs) and interictal epileptiform discharges (IEDs) have been shown to be markers of epileptogenic regions. However, there is currently no 'gold standard' for identifying HFOs. Accordingly, we aimed to formally characterize the interrater reliability of HFO markings to validate the current practices. METHODS: A morphology detector was implemented to detect events (candidate HFOs, lower-threshold events, and distractors) from the intracranial EEG (iEEG) of ten patients...
December 30, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Zhi Song, Xinbin Cheng, Hongping Ma, Jinlong Zhang, Bin Ma, Hongfei Jiao, Zhanshan Wang
The influence of coating thickness on laser-induced damage (LID) characteristics of anti-reflection (AR) coatings irradiated by 1064 nm nanosecond laser pulses was investigated. Two HfO<sub>2</sub>/SiO<sub>2</sub> AR coatings with different physical thicknesses, 0.7 and 2.7 μm, were prepared and tested. To study the effect of coating thickness on a laser-induced damage threshold (LIDT) in isolation, electric field intensities (EFIs) at the substrate-coating interface were kept the same by using proper AR designs...
February 1, 2017: Applied Optics
Drew Schiltz, Dinesh Patel, Cory Baumgarten, Brendan A Reagan, Jorge J Rocca, Carmen S Menoni
Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub> high reflection (HR) interference coatings for λ∼1  μm offer superior performance at high irradiance conditions. However, these coatings are not good candidates for high peak power conditions in comparison to HfO<sub>2</sub>/SiO<sub>2</sub> multilayer stacks. Here we show that the modification of the top layers design of a quarter wave Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub> high reflector leads to 4-5 fold increase in the laser damage fluence compared to a quarter wave (Ta<sub>2</sub>O<sub>5</sub>/SiO<sub>2</sub>)<sup>15</sup> when tested at λ=1...
February 1, 2017: Applied Optics
Svetlana Shestaeva, Astrid Bingel, Peter Munzert, Lilit Ghazaryan, Christian Patzig, Andreas Tünnermann, Adriana Szeghalmi
Structural, optical, and mechanical properties of Al<sub>2</sub>O<sub>3</sub>, SiO<sub>2</sub>, and HfO<sub>2</sub> materials prepared by plasma-enhanced atomic layer deposition (PEALD) were investigated. Residual stress poses significant challenges for optical coatings since it may lead to mechanical failure, but in-depth understanding of these properties is still missing for PEALD coatings. The tensile stress of PEALD alumina films decreases with increasing deposition temperature and is approximately 100 MPa lower than the stress in thermally grown films...
February 1, 2017: Applied Optics
Lei Zhang, Xinbin Cheng, Jinlong Zhang, Hongfei Jiao, Ganghua Bao, Tao Ding, Zhanshan Wang
The grain sizes and their influence on the roughness of an HfO<sub>2</sub> single layer prepared with ion-assisted deposition were investigated. Three methods, x ray diffractometry, atomic force microscopy, and the k-correlated power spectral density function model, were used to obtain the grain sizes in two HfO<sub>2</sub> single layers with 16 and 20 nm thicknesses. X ray diffractometry showed that the grain sizes were about 7 and 9 nm, respectively, whereas the other two methods demonstrated that the grain sizes were about 14 and 16 nm...
February 1, 2017: Applied Optics
Chih-Wei Chang, Yue-Loong Hsin, Wentai Liu
Mapping the electric field of the brain with electrodes benefits from its superior temporal resolution but is prone to low spatial resolution property comparing with other modalities such as fMRI, which can directly impact the precision of clinical diagnosis. Simulations show that dense arrays with straightforwardly miniaturized electrodes in terms of size and pitch may not improve the spatial resolution but only strengthen the cross coupling between adjacent channels due to volume conduction. We present a new spatially focused method to improve the electrode spatial selectivity and consequently suppress the neural signal coupling from the sources in the vicinity...
March 7, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Laura Uva, Davide Boido, Massimo Avoli, Marco de Curtis, Maxime Lévesque
We analyzed the patterns of seizure-like activity and associated high-frequency oscillations (HFOs) induced by the K(+) channel blocker 4-aminopyridine (4AP, 50μM) or the GABAA receptor antagonist bicuculline methiodide (BMI, 50μM) in the in vitro isolated guinea pig brain preparation. Extracellular field recordings were obtained from the medial entorhinal cortex (EC) using glass pipettes or silicon probes; 4AP or BMI were applied through the basilar artery. Ripples (80-200Hz) or fast ripples (250-500Hz) occurred at higher rates shortly before ictal events induced by 4AP or BMI, respectively...
January 6, 2017: Epilepsy Research
Lijuan Huo, Xibai Zeng, Shiming Su, Lingyu Bai, Yanan Wang
Hydrous ferric oxide (HFO) is most effective with high treatment capacity on arsenate [As(V)] sorption although its transformation and aggregation nature need further improvement. Here, HFO nanoparticles with carboxymethyl cellulose (CMC) or starch as modifier was synthesized for the purpose of stability improvement and As(V) removal from water. Comparatively, CMC might be the optimum stabilizer for HFO nanoparticles because of more effective physical and chemical stability. The large-pore structure, high surface specific area, and the non-aggregated nature of CMC-HFO lead to increased adsorption sites, and thus high adsorption capacities of As(V) without pre-treatment (355 mg·g(-1)), which is much greater than those reported in previous studies...
January 18, 2017: Scientific Reports
Runze Han, Peng Huang, Yudi Zhao, Zhe Chen, Lifeng Liu, Xiaoyan Liu, Jinfeng Kang
In this paper, resistive random access memory (RRAM)-based crossbar arrays with the cell structure of Pt/[AlO y /HfO x ] m /TiN were fabricated by using atomic layer deposition (ALD) technique. The RRAM devices in the arrays show excellent performances such as good uniformity and high reliability. Based on the fabricated RRAM array, a complete set of basic logic operations including NOR and XNOR were successfully demonstrated.
December 2017: Nanoscale Research Letters
John Kealy, Sean Commins, John P Lowry
Non-competitive NMDA receptor antagonists are known to induce psychosis-like symptoms in rodents. Administration of such compounds cause behavioural effects such as memory impairment and hyperlocomotion. Additionally, drugs such as phencyclidine (PCP), ketamine and MK-801 all cause distinctive increases in striatal local field potential (LFP) in the high frequency oscillation (HFO) band in the power spectrum (140-180 Hz). Amperometric sensors provide a means to measure tissue oxygen (tO2; a BOLD-like signal) in the brains of freely-moving rats while simultaneously acquiring LFP using the same electrode...
January 11, 2017: Neuropharmacology
Florian Streitparth, Christian Althoff, Martin Jonczyk, Felix Guettler, Martin Maurer, Hendrik Rathke, Keno Moritz Sponheuer, Bernd Hamm, Ulf K Teichgräber, Maximilian de Bucourt
OBJECTIVES: To assess the feasibility, image quality, and accuracy of freehand biopsies of liver, bone, muscle, vertebral disc, soft tissue, and other lesions using balanced steady-state free precession (SSFP, balanced fast field echo: bFFE), spoiled and nonspoiled gradient echo (FFE), and turbo spin echo (TSE) sequences for interactive continuous navigation in an open magnetic resonance imaging (MRI) system at 1.0 tesla (T). METHODS: Twenty-six MR-guided biopsies (five liver, five bone, four muscle, four vertebral disc, one lung, one kidney, one suprarenal gland, and five soft or other tissue) were performed in 23 patients in a 1...
January 11, 2017: Biomedizinische Technik. Biomedical Engineering
Jonas C Bruder, Matthias Dümpelmann, Daniel Lachner Piza, Malenka Mader, Andreas Schulze-Bonhage, Julia Jacobs-Le Van
High frequency oscillations (HFOs, 80-500[Formula: see text]Hz) serve as novel electroencephalography (EEG) markers of epileptic tissue. The differentiation of physiological and epileptic HFO is an important challenge and is complicated by the fact that both types are generated in mesiotemporal structures. This study aimed to identify oscillation features that serve to distinguish physiological ripples associated with sleep spindles and epileptic ripples. We studied 19 patients with chronic intracranial EEG(iEEG) with mesiotemporal implantation and simultaneous scalp EEG...
November 2, 2016: International Journal of Neural Systems
Pradeep Kumar Rao, Shridhar P Gejji
HFO-1345fz (CF3CF2CH═CH2 or 3,3,4,4,4-pentafluoro-1-butene) belongs to a class of hydrofluoro-olefins and represents a new generation of potential foam expansion agents. Its atmospheric impact and environmental acceptability can be estimated from the studies of kinetics and mechanism of its oxidative degradation. The molecular insights accompanying the reaction pathways in terms of the characterization of intermediates or products and radiative properties should prove useful for large-scale industrial applications...
January 12, 2017: Journal of Physical Chemistry. A
Juan G Ochoa, Walter G Rusyniak
Objective. Review presurgical use of ictal HFO mapping to detect ictal activation areas with dual seizure focus in both the temporal and extratemporal cortex. Methods. Review of consecutive patients admitted to the University of South Alabama Epilepsy Monitoring Unit (SouthCEP) between January 2014 and October 2015, with suspected temporal lobe epilepsy and intracranial electrode recording. Ictal HFO localization was displayed in 3D reconstructed brain images using the patient's own coregistered magnetic resonance imaging (MRI) and computed tomography (CT) with the implanted electrodes...
2016: Neurology Research International
Ming Hua, Bowen Yang, Chao Shan, Weiming Zhang, Shiya He, Lu Lv, Bingcai Pan
As(V) and Cr(VI) are both highly toxic anionic pollutants and commonly co-exist in some industrial effluents and contaminated waters. In this study, simultaneous removal of them was efficiently achieved by employing a composite adsorbent (HFO-201) fabricated by immobilizing nanoscale hydrous ferric oxide (HFO) within a macroporous anion exchanger D201. The HFO-201 composite possesses two types of adsorption sites, i.e. the quaternary ammonium groups fixed on the D201 matrix and the embedded HFO nanoparticles...
December 18, 2016: Chemosphere
Seung Han Baek, Minkyung Kim, Minjoo Kim, Miso Kang, Hye Jin Yoo, Nan Hee Lee, Yong Hwan Kim, Min Song, Jong Ho Lee
OBJECTIVE: To screen the metabolomes of both overweight subjects with low visceral fat area (LFO) and high visceral fat area (HFO) to identify potential metabolites that are associated with the different metabolic characteristics. METHODS: The metabolic characteristics of 112 overweight (25 kg/m(2)  ≤ BMI < 30 kg/m(2) ) Korean individuals aged 30 to 65 years were examined. Plasma metabolomic profiling of HFO [visceral fat area (VFA) at L4 ≥ 100 cm(2) ] and LFO (L4 VFA <100 cm(2) ) individuals matched for age, gender, and BMI was performed...
December 21, 2016: Obesity
Yipin Zhang, Zhengkui Li
A new polymer-supported hybrid adsorbent (HFO-P(TAA/HEA)) for highly efficient removal of Pb(2+), Cu(2+), Cd(2+) and Ni(2+) from wastewater was developed by supporting hydrous ferric oxide (HFO) nanoparticles onto a porous poly(trans-Aconitic acid/2-hydroxyethyl acrylate) hydrogel (P(TAA/HEA)) with in situ precipitation method. Swelling kinetics, scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), Fourier transform infrared spectra (FTIR) and X-ray photoelectron spectroscopy (XPS) were used for characterization of the prepared HFO-P(TAA/HEA)...
December 13, 2016: Science of the Total Environment
Lauren A Shreve, Anca Velisar, Mahsa Malekmohammadi, Mandy Miller Koop, Megan Trager, Emma J Quinn, Bruce C Hill, Zack Blumenfeld, Camilla Kilbane, Alessandra Mantovani, Jaimie M Henderson, Helen Brontë-Stewart
OBJECTIVE: Determine the incidence of resting state oscillations in alpha/beta, high frequency (HFO) bands, and their phase amplitude coupling (PAC) in a large cohort in Parkinson's disease (PD). METHODS: Intra-operative local field potentials (LFPs) from subthalamic nucleus (STN) were recorded from 100 PD subjects, data from 74 subjects were included in the analysis. RESULTS: Alpha/beta oscillations were evident in >99%, HFO in 87% and PAC in 98% of cases...
January 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Martin Pail, Pavel Řehulka, Jan Cimbálník, Irena Doležalová, Jan Chrastina, Milan Brázdil
OBJECTIVE: The purpose of the presented study is to determine whether there are frequency-independent high-frequency oscillation (HFO) parameters which may differ in epileptic and non-epileptic regions. METHODS: We studied 31 consecutive patients with medically intractable focal (temporal and extratemporal) epilepsies who were examined by either intracerebral or subdural electrodes. Automated detection was used to detect HFO. The characteristics (rate, amplitude, and duration) of HFO were statistically compared within three groups: the seizure onset zone (SOZ), the irritative zone (IZ), and areas outside the IZ and SOZ (nonSOZ/nonIZ)...
January 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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