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Jianshu Ni, Nailong Cao, Xiaohu Wang, Changsheng Zhan, Jiemin Si, Baojun Gu, Karl-Erik Andersson
OBJECTIVES: To examine the effect of intrathecal 5-HT7 agonist administration on voiding function in urethane-anesthetized rat, and the change of 5-HT7 receptor expression in lumbosacral cord Onuf's nucleus after SCI. MATERIALS AND METHODS: Thirty-two female Sprague-Dawley (SD) rats were divided into spinally intact (SI) group and SCI group (n=16 each). Eight weeks after transection, half of the rats underwent continuous cystometry under urethane anesthetization, and the 5-HT7 selective agonist LP44 was given intrathecally...
May 21, 2018: BJU International
Ching-Lin Fan, Fan-Ping Tseng, Chiao-Yuan Tseng
In this work, amorphous indium-gallium-zinc oxide thin-film transistors (a-IGZO TFTs) with a HfO₂ gate insulator and CF₄ plasma treatment was demonstrated for the first time. Through the plasma treatment, both the electrical performance and reliability of the a-IGZO TFT with HfO₂ gate dielectric were improved. The carrier mobility significantly increased by 80.8%, from 30.2 cm²/V∙s (without treatment) to 54.6 cm²/V∙s (with CF₄ plasma treatment), which is due to the incorporated fluorine not only providing an extra electron to the IGZO, but also passivating the interface trap density...
May 17, 2018: Materials
Marjan Salari, Gholam Reza Rakhshandehroo, Mohammad Reza Nikoo
The main purpose of this experimental study was to optimize Homogeneous Fenton oxidation (HFO) and identification of oxidized by-products from degradation of Ciprofloxacin (CIP) using hybrid AHP-PROMETHEE, Response Surface Methodology (RSM) and High Performance Liquid Chromatography coupled with Mass Spectrometry (HPLC-MS). At the first step, an assessment was made for performances of two catalysts (FeSO4 ·7H2 O and FeCl2 ·4H2 O) based on hybrid AHP-PROMETHEE decision making method. Then, RSM was utilized to examine and optimize the influence of different variables including initial CIP concentration, Fe2+ concentration, [H2 O2 ]/[ Fe2+ ] mole ratio and initial pH as independent variables on CIP removal, COD removal, and sludge to iron (SIR) as the response functions in a reaction time of 25 min...
April 23, 2018: Chemosphere
Meina Duan, Deqi Xiong, Mengye Yang, Yijun Xiong, Guanghui Ding
The present study investigated the toxic effects of parental (maternal/paternal) exposure to heavy fuel oil (HFO) on the adult reproductive state, gamete quality and development of the offspring of the sea urchin Strongylocentrotus intermedius. Adult sea urchins were exposed to effluents from HFO-oiled gravel columns for 7 days to simulate an oil-contaminated gravel shore, and then gametes of adult sea urchins were used to produce embryos to determine developmental toxicity. For adult sea urchins, no significant difference in the somatic size and weight was found between the various oil loadings tested, while the gonad weight and gonad index were significantly decreased at higher oil loadings...
May 3, 2018: Ecotoxicology and Environmental Safety
Qiuhong Tan, Qianjin Wang, Yingkai Liu, Hailong Yan, Wude Cai, Zhikun Yang
Ferroelectric field-effect transistors (FeFETs) with single-walled carbon nanotube (SWCNT) dominated micron-wide stripe patterned as channel, (Bi,Nd)4 Ti3 O12 films as insulator, and HfO2 films as defect control layer were developed and fabricated. The prepared SWCNT-FeFETs possess excellent properties such as large channel conductance, high on/off current ratio, high channel carrier mobility, great fatigue endurance performance, and data retention. Despite its thin capacitance equivalent thickness, the gate insulator with HfO2 defect control layer shows a low leakage current density of 3...
April 27, 2018: Nanoscale Research Letters
Munkhbayar Baasandorj, Paul Marshall, Robert L Waterland, Akkihebbal R Ravishankara, James B Burkholder
Rate coefficients, k, for the gas-phase reaction of the OH radical with (E) CF3CH=CHCF3 ((E)-1,1,14,4,4-hexafluoro-2-butene, HFO-1336mzz(E)) were measured over a range of temperature (211-374 K) and bath gas pressure (20-300 Torr; He, N2) using a pulsed laser photolysis-laser induced fluorescence (PLP-LIF) technique. k1(T) was independent of pressure over this range of conditions with k1(296 K) = (1.31 ± 0.15) × 10 13 cm3 molecule 1 s 1 and k1(T) = (6.94 ± 0.80) × 10 13 exp[ (496 ± 10)/T] cm3 molecule 1 s 1, where the uncertainties are 2 and the pre-exponential term includes estimated systematic error...
April 25, 2018: Journal of Physical Chemistry. A
Jack Strand, Moloud Kaviani, David Z Gao, Al-Moatasem El-Sayed, Valeri V Afanas'ev, Alexander L Shluger
We review the current understanding of intrinsic electron and hole trapping in insulating amorphous oxide films on semiconductor and metal substrates. The experimental and theoretical evidences are provided for the existence of intrinsic deep electron and hole trap states caused by the disorder of amorphous metal oxide films. We start from presenting the results for amorphous (a) HfO<sub>2</sub>, chosen due to the availability of highest purity amorphous films, which is vital for studying their intrinsic electronic properties...
April 25, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Joel Corbin, Amewu Antoinette Mensah, Simone Maria Pieber, Jürgen Orasche, Bernhard Michalke, Marco Zanatta, Hendryk Czech, Dario Massabò, Francesco Buatier de Mongeot, Carlo Mennucci, Imad El Haddad, Nivedita K Kumar, Benjamin Stengel, Yuting Huang, Ralf Zimmermann, Andre S H Prevot, Martin Gysel
Heavy fuel oil (HFO) particulate matter (PM) emitted by marine engines is known to contain toxic heavy metals including vanadium (V) and nickel (Ni). The toxicity of such metals will depend on the their chemical state, size distribution, and mixing state. Using online soot-particle aerosol mass spectrometry (SP-AMS), we quantified the mass of five metals (V, Ni, Fe, Na, and Ba) in HFO-PM soot particles produced by a marine diesel research engine. The in-soot metal concentrations were compared to 25 in-PM 2...
April 24, 2018: Environmental Science & Technology
Duangkamol Mantor, Wasana Pratchayasakul, Wanitchaya Minta, Wissuta Sutham, Siripong Palee, Jirapas Sripetchwandee, Sasiwan Kerdphoo, Thidarat Jaiwongkum, Sirawit Sriwichaiin, Warunsorn Krintratun, Nipon Chattipakorn, Siriporn C Chattipakorn
Our previous study demonstrated that obesity aggravated peripheral insulin resistance and brain dysfunction in the ovariectomized condition. Conversely, the effect of obesity followed by oophorectomy on brain oxidative stress, brain apoptosis, synaptic function and cognitive function, particularly in hippocampal-dependent and hippocampal-independent memory, has not been investigated. Our hypothesis was that oophorectomy aggravated metabolic impairment, brain dysfunction and cognitive impairment in obese rats...
April 17, 2018: Experimental Gerontology
Joonsung Ahn, Tae Whan Kim
Carrier transport mechanisms via a high-k gate dielectric material of hafnium dioxide (HfO2) between III-V GaAs were investigated by using a non-equilibrium Green's function (NEGF). The full band structure for the HfO2 layer was determined by using a sp3d5s* closest neighbor empirical tight-binding model. The band structure of the GaAs bulk was determined by using an empirical tight-binding model. The tunneling currents dependent on the thickness of the HfO2 layer with a GaAs layer were obtained by solving the NEGF in an open boundary condition...
September 1, 2018: Journal of Nanoscience and Nanotechnology
Hyunki Kim, Pyungho Choi, Nayoung Lee, Soonkon Kim, Kwangjun Koo, Jaehyeong Lee, Byoungdeog Choi
Hafnium-silicate (HfSiO4, (HfO2)x(SiO2)1-x) and hafnium-zirconate (HfZrO4, (HfO2)x(ZrO2)1-x) films were employed as a gate dielectric to enhance the electrical properties of pure HfO2. (HfO2)x(SiO2)1-x and (HfO2)x(ZrO2)1-x films were formed onto p-Si substrates with varying degrees of Hf content x (x = 1, 0.9, 0.7, and 0.5) via solution processing. With regard to (HfO2)x(SiO2)1-x, the leakage current decreased from 1.94 × 10-8 to 4.29 × 10-9 A/cm2 at a gate voltage of VG = -1 V when the HfO2 content was reduced...
September 1, 2018: Journal of Nanoscience and Nanotechnology
P Gong, Z X Yang, J Xue, P Qian, H P Yang, X Y Liu, K G Bian
OBJECTIVE: To investigate the clinical significance of high-frequency oscillations (HFOs) on scalp electroencephalography (EEG) in patients with epileptic encephalopathy with continuous spike-and-wave during sleep (CSWS). METHODS: Twenty-one CSWS patients treated for epilepsy from January 2006 to December 2016 in Pediatric Department of Peking University First Hospital were enrolled into the study. Selected clinical variables including gender, age parameters, seizure frequencies and antiepileptic drugs were compared between (a)...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Mazlum Sahin, Helin El, Ibrahim Akkoç
Background: To clarify the efficiency of mask O2 and high-flow O2 (HFO) treatments following cardiopulmonary bypass (CPB) in obese patients. Methods: During follow-up, oxygenization parameters including arterial pressure of oxygen (PaO2 ), peripheral oxygen saturation (SpO2 ), and arterial partial pressure of carbon dioxide (PaCO2 ) and physical examination parameters including respiratory rate, heart rate, and arterial pressure were recorded respectively. Presence of atelectasia and dyspnea was noted...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Su Liu, Michael M Quach, Daniel J Curry, Monika Ummat, Elaine Seto, Nuri F Ince
Epilepsy associated with cavernous malformation (CM) often requires surgical resection of seizure focus to achieve seizure-free outcome. High-frequency oscillations (HFOs) in intracranial electroencephalogram (EEG) are reported as potential biomarkers of epileptogenic regions, but to our knowledge there are no data on the existence of HFOs in CM-caused epilepsy. Here we report our experience of the identification of the seizure focus in a 3-year-old pediatric patient with intractable epilepsy associated with CM...
June 2017: Epilepsia Open
Lucia Rita Quitadamo, Roberto Mai, Francesca Gozzo, Veronica Pelliccia, Francesco Cardinale, Stefano Seri
Pathological High-Frequency Oscillations (HFOs) have been recently proposed as potential biomarker of the seizure onset zone (SOZ) and have shown superior accuracy to interictal epileptiform discharges in delineating its anatomical boundaries. Characterization of HFOs is still in its infancy and this is reflected in the heterogeneity of analysis and reporting methods across studies and in clinical practice. The clinical approach to HFOs identification and quantification usually still relies on visual inspection of EEG data...
January 15, 2018: International Journal of Neural Systems
Nattayaporn Apaiajai, Titikorn Chunchai, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Siriporn C Chattipakorn, Nipon Chattipakorn
BACKGROUND: We have previously reported that testosterone deprivation at a very young age accelerated, but did not aggravate, left-ventricular (LV) dysfunction in obese insulin-resistant rats. However, the effects of testosterone deprivation during adulthood on LV function in obese insulin-resistant rats remains unclear. We hypothesized that testosterone deprivation aggravates LV dysfunction and cardiac autonomic imbalance via the impairment of cardiac mitochondrial function and dynamics proteins, a reduction in insulin receptor function, and an increase in apoptosis in obese insulin-resistant rats...
March 22, 2018: Gerontology
Lijuan Huo, Daoyou Huang, Xibai Zeng, Shiming Su, Yanan Wang, Lingyu Bai, Cuixia Wu
This study investigated arsenic (As) availability and uptake by rape (Brassica campestris L.) during two harvest periods of carboxymethyl cellulose (CMC)-stabilized ferrihydrite (HFO) nanoparticles for in situ treatment As-contaminated soil. Application of modified HFO nanoparticles in soils not only provided a larger specific surface area but also markedly improved stability against aggregation and recrystallization. For 90-day incubation, bare HFO particles were gradually converted to the crystalline Fe(III) oxide form, although this was not observed for the 0...
March 19, 2018: Environmental Science and Pollution Research International
Sarah Schnitzler, Christian Johannes Hartmann, Stefan Jun Groiss, Lars Wojtecki, Alfons Schnitzler, Jan Vesper, Jan Hirschmann
OBJECTIVE: To assess whether high frequency oscillations (HFOs, >150 Hz), known to occur in basal ganglia nuclei, can be observed in the thalamus. METHODS: We recorded intraoperative local field potentials from the ventral intermediate nucleus (VIM) of the thalamus in patients with Essential Tremor (N = 16), Parkinsonian Tremor (3), Holmes Tremor (2) and Dystonic Tremor (1) during implantation of electrodes for deep brain stimulation. Recordings were performed with up to five micro/macro-electrodes that were simultaneously advanced to the stereotactic target...
February 19, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Benjamin R Pittman-Polletta, Allison Quach, Ali I Mohammed, Michael Romano, Krishnakanth Kondabolu, Nancy J Kopell, Xue Han, Michelle M McCarthy
Cortico-basal ganglia-thalamic (CBT) β oscillations (15-30 Hz) are elevated in Parkinson's disease and correlated with movement disability. To date, no experimental paradigm outside of loss of dopamine has been able to specifically elevate β oscillations in the CBT loop. Here, we show that activation of striatal cholinergic receptors selectively increased β oscillations in mouse striatum and motor cortex. In individuals showing simultaneous β increases in both striatum and M1, β partial directed coherence (PDC) increased from striatum to M1 (but not in the reverse direction)...
March 12, 2018: European Journal of Neuroscience
Lin Li, Mayur Patel, Joyel Almajano, Jerome Engel, Anatol Bragin
The current study aimed to investigate the spatial and temporal patterns of high-frequency oscillations (HFOs) in the intra-/extrahippocampal areas during epileptogenesis. Local field potentials were bilaterally recorded from hippocampus (CA1), thalamus, motor cortex, and prefrontal cortex in 13 rats before and after intrahippocampal kainic acid (KA) lesions. HFOs in the ripple (100-200 Hz) and fast ripple (250-500 Hz) ranges were detected and their rates were computed during different time periods (1-5 weeks) after KA-induced status epilepticus (SE)...
April 2018: Epilepsia
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