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https://www.readbyqxmd.com/read/27889627/subthalamic-oscillations-and-phase-amplitude-coupling-are-greater-in-the-more-affected-hemisphere-in-parkinson-s-disease
#1
Lauren A Shreve, Anca Velisar, Mahsa Malekmohammadi, Mandy Miller Koop, Megan Trager, Emma J Quinn, Bruce C Hill, Zack Blumenfeld, Camilla Kilbane, Alessandra Mantovani, Jaimie M Henderson, Helen Brontë-Stewart
OBJECTIVE: Determine the incidence of resting state oscillations in alpha/beta, high frequency (HFO) bands, and their phase amplitude coupling (PAC) in a large cohort in Parkinson's disease (PD). METHODS: Intra-operative local field potentials (LFPs) from subthalamic nucleus (STN) were recorded from 100 PD subjects, data from 74 subjects were included in the analysis. RESULTS: Alpha/beta oscillations were evident in >99%, HFO in 87% and PAC in 98% of cases...
November 10, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27883965/frequency-independent-characteristics-of-high-frequency-oscillations-in-epileptic-and-non-epileptic-regions
#2
Martin Pail, Pavel Řehulka, Jan Cimbálník, Irena Doležalová, Jan Chrastina, Milan Brázdil
OBJECTIVE: The purpose of the presented study is to determine whether there are frequency-independent high-frequency oscillation (HFO) parameters which may differ in epileptic and non-epileptic regions. METHODS: We studied 31 consecutive patients with medically intractable focal (temporal and extratemporal) epilepsies who were examined by either intracerebral or subdural electrodes. Automated detection was used to detect HFO. The characteristics (rate, amplitude, and duration) of HFO were statistically compared within three groups: the seizure onset zone (SOZ), the irritative zone (IZ), and areas outside the IZ and SOZ (nonSOZ/nonIZ)...
October 29, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27875125/time-frequency-strategies-for-increasing-high-frequency-oscillation-detectability-in-intracerebral-eeg
#3
Nicolas Roehri, Jean-Marc Lina, John C Mosher, Fabrice Bartolomei, Christian-George Benar
BACKGROUND: High-frequency oscillations (HFOs) are considered to be highly representative of brain tissues capable of producing epileptic seizures. The visual review of HFOs on intracerebral electroencephalography is time consuming and tedious, and it can be improved by time-frequency (TF) analysis. The main issue is that the signal is dominated by lower frequencies that mask the HFOs. Our aim was to flatten (i.e., whiten) the frequency spectrum to enhance the fast oscillations while preserving an optimal signal to noise ratio (SNR)...
December 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27858801/study-on-the-effects-of-soluble-microbial-product-on-phosphate-adsorption-onto-fresh-hydrous-ferric-oxides-by-surface-complexation-models
#4
Yanpeng Mao, Wenlong Wang, Chunyuan Ma
As one of the major soluble organic compounds in membrane bioreactors, soluble microbial product (SMP) can combine the surface sites on hydrous ferric oxides (HFO), which can compete with HFO for the uptake of phosphate. In this study, SMP was extracted from an MBR plant with long-term stable operation, and the effects of SMP on phosphate adsorption onto fresh HFO (FHFO) were investigated at pH values of 6.0 and 7.8 in a two-phase system composed of FHFO (solid phase) and SMP/phosphate (liquid phase). The phosphate adsorption capacity of FHFO was found to decrease significantly with increase in the pH value and SMP concentration...
November 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/27834669/a-translational-cellular-model-to-study-the-impact-of-high-frequency-oscillatory-ventilation-hfov-on-human-epithelial-cell-function
#5
Anja Karolin Mowes, Beatriz E de Jongh, Timothy Cox, Yan Zhu, Thomas H Shaffer
High frequency oscillatory ventilation (HFOV) has been proposed as gentle ventilation strategy to prevent lung injury in the preterm infant. High frequency ventilation leads to dimensional and mechanical airway deformation in animal airway models, which is consistent with translational studies demonstrating the impact of oxygen and biophysical stresses on normal airway cellular function. There is an overall paucity of clinical and cellular data on the impact of HFOV on the conducting airway. We developed an innovative method to test the impact of the clinical HFO Ventilator (Sensormedic 3100A) on human epithelial cell function...
November 10, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27819216/a-post-weaning-fish-oil-dietary-intervention-reverses-adverse-metabolic-outcomes-and-11%C3%AE-hydroxysteroid-dehydrogenase-type-1-expression-in-postnatal-overfed-rats
#6
Yanyan Dai, Fan Yang, Nan Zhou, Lijun Sha, Shanshan Zhou, Junle Wang, Xiaonan Li
Early life is considered a critical period for determining long-term metabolic health. Postnatal over-nutrition may alter glucocorticoid (GC) metabolism and increase the risk of developing obesity and metabolic disorders in adulthood. Our aim was to assess the effects of the dose and timing of a fish oil diet on obesity and the expression of GC-activated enzyme 11β-hydroxysteroid dehydrogenase type 1 (HSD1) in postnatal overfed rats. Litter sizes were adjusted to three (small litter (SL)) or ten (normal litter) rats on postnatal day 3 to induce overfeeding or normal feeding...
November 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27778268/the-influence-of-hydrous-ferric-oxide-earthworms-and-a-hypertolerant-plant-on-arsenic-and-iron-bioavailability-fate-and-transport-in-soils
#7
Benjamin C Maki, Kathryn R Hodges, Scott C Ford, Ruth M Sofield
Historic applications of lead arsenate pesticides and smelting activities have resulted in elevated concentrations of arsenic in Washington State soils. For example, old orchard topsoils in Washington have concentrations reaching upwards of 350 mg As/kg soil with an estimated 187,590 acres of arsenic contamination from pesticide application alone. Iron oxides have been indicated as a key factor in modulating the fate and transport of arsenic in the soil environment. We employed a factorial design to investigate the role of a specific iron oxide, hydrous ferric oxide (HFO), and terrestrial organisms on the mobility, bioavailability, and fate of arsenic and iron in locally collected soils...
October 24, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27773440/a-simple-model-to-predict-chromate-partitioning-in-selected-soils-from-china
#8
Xueyuan Gu, Jinyu Xie, Xiaorong Wang, Les J Evans
Due to its mobility and toxicity, chromate [Cr(VI)] partitioning in soils, especially in the vadose zone, is an important environmental concern. The aim of this study was to develop a mechanism-based multi-surface complexation model using published parameters to predict the soil/water partitioning of Cr(VI) in 12 soils (previously depleted of organic matter) from China. The retention of Cr(VI) in soils was attributed to two reactive oxide surfaces: goethite and hydrous ferric oxide (HFO); however, modeling results showed that the best prediction was obtained with goethite alone, whereas the addition of HFO resulted in an overestimation of adsorption in some soils...
October 17, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27764594/fast-accurate-localization-of-epileptic-seizure-onset-zones-based-on-detection-of-high-frequency-oscillations-using-improved-wavelet-transform-and-matching-pursuit-methods
#9
Min Wu, Ting Wan, Xiongbo Wan, Yuxiao Du, Jinhua She
This letter describes the improvement of two methods of detecting high-frequency oscillations (HFO) and their use to localize epileptic seizure onset zones (SOZs). The wavelet transform (WT) method was improved by combining the complex Morlet WT with Shannon entropy to enhance the temporal-frequency resolution during HFO detection. And the matching pursuit (MP) method was improved by combining it with an adaptive genetic algorithm to improve the speed and accuracy of the calculations for HFO detection. The HFOs detected by these two methods were used to localize SOZs in five patients...
October 20, 2016: Neural Computation
https://www.readbyqxmd.com/read/27754660/polyphosphates-and-fulvates-enhance-environmental-stability-of-po4-bearing-colloidal-iron-oxyhydroxides
#10
Jessica Bollyn, Mathias Nijsen, Stijn Baken, Iris J Joye, Nadia Waegeneers, Geert Cornelis, Erik Smolders
Iron oxyhydroxide nanoparticles (Fe-NPs) are natural vectors of phosphate (PO4) in the environment. Their mobility is determined by colloidal stability, which is affected by surface composition. This might be manipulated in engineered NPs for environmental or agricultural applications. Here, stability of PO4-Fe-NPs (HFO/goethite) was determined across contrasting environmental conditions (pH, Ca) and by using fulvates (FA) and polyphosphates as coatings. The PO4-Fe-NPs are unstable at Ca concentrations above 0...
October 18, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27739456/kinetic-modeling-of-phosphate-adsorption-by-preformed-and-in-situ-formed-hydrous-ferric-oxides-at-circumneutral-ph
#11
Yanpeng Mao, Qinyan Yue
Kinetics of phosphate removal by Fe(III) was investigated by both preformed and in situ formed hydrous ferric oxides (HFO) at pH 6.0-8.0. A pseudo-second-order empirical model was found to adequately describe phosphate removal in the two cases. The Elovich and intra-particle diffusion models, however, were only capable of describing phosphate adsorption to preformed HFO (PF-HFO). By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0...
October 14, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27733815/gpi-oscillatory-activity-differentiates-tics-from-the-resting-state-voluntary-movements-and-the-unmedicated-parkinsonian-state
#12
Joohi Jimenez-Shahed, Ilknur Telkes, Ashwin Viswanathan, Nuri F Ince
Background: Deep brain stimulation (DBS) is an emerging treatment strategy for severe, medication-refractory Tourette syndrome (TS). Thalamic (Cm-Pf) and pallidal (including globus pallidus interna, GPi) targets have been the most investigated. While the neurophysiological correlates of Parkinson's disease (PD) in the GPi and subthalamic nucleus (STN) are increasingly recognized, these patterns are not well characterized in other disease states. Recent findings indicate that the cross-frequency coupling (CFC) between beta band and high frequency oscillations (HFOs) within the STN in PD patients is pathologic...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27658648/high-butter-fat-diet-and-bisphenol-a-additively-impair-male-rat-spermatogenesis
#13
Pheruza Tarapore, Max Hennessy, Dan Song, Jun Ying, Bin Ouyang, Vinothini Govindarajah, Yuet-Kin Leung, Shuk-Mei Ho
Exposure to xenoestrogens is a probable cause of male infertility in humans. Consumption of high-fat diets and exposure to bisphenol A (BPA) is pervasive in America. Here, we test the hypothesis that gestational exposure to high dietary fats and/or BPA disrupt spermatogenesis in adulthood. Sprague-Dawley rats were fed diets containing 10kcal% butter fat (AIN), 39kcal% butter fat (HFB), or 39kcal% olive oil (HFO), with or without BPA (25μg/kg body weight/day) during pregnancy. One group of male offspring received testosterone (T)- and estradiol-17β (E2)-filled implants or sham-implants from postnatal day (PND)70-210...
September 19, 2016: Reproductive Toxicology
https://www.readbyqxmd.com/read/27642833/study-on-sulfadimethoxine-removal-from-aqueous-solutions-by-hydrous-ferric-oxides
#14
Weixiao Zhu, Jianduo Wang, Yili Wang, Hongjie Wang
Significant concerns have been raised over the presence of antibiotics including sulfadimethoxine (SDMO) in aquatic environments. This study investigated the removal capability and mechanism involved in the removal of SDMO by hydrous ferric oxides (HFO). Results showed that SDMO removal was highly pH and ionic strength dependent. The pseudo-first-order model fitted well the kinetic results, and the value of the calculated activation energy for SDMO adsorption onto HFO was 8.6 kJ mol(-1). Adsorption isotherms at varied temperatures were well described by the Langmuir model...
September 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/27635628/intracranial-eeg-seizure-onset-patterns-correlate-with-high-frequency-oscillations-in-patients-with-drug-resistant-epilepsy
#15
Taissa Ferrari-Marinho, Piero Perucca, Francois Dubeau, Jean Gotman
OBJECTIVE: High-frequency oscillations (80-500Hz; HFOs) have been shown to be a specific biomarker of the seizure-onset zone. The relationship of HFOs with seizures having different intracranial electroencephalography (iEEG) morphological onsets, however, has shown significant relationships in experimental animals but has not been studied in humans. We investigated how interictal and ictal HFOs relate to different seizure-onset morphological patterns. METHODS: We analyzed the most representative seizure type of 37 patients with drug-resistant focal epilepsy who underwent iEEG for diagnostic evaluation...
September 6, 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27634210/multivariate-analytical-figures-of-merit-as-a-metric-for-evaluation-of-quantitative-measurements-using-comprehensive-two-dimensional-gas-chromatography-mass-spectrometry
#16
Ali Eftekhari, Hadi Parastar
The present contribution is devoted to develop multivariate analytical figures of merit (AFOMs) as a new metric for evaluation of quantitative measurements using comprehensive two-dimensional gas chromatography-mass spectrometry (GC×GC-MS). In this regard, new definition of sensitivity (SEN) is extended to GC×GC-MS data and then, other multivariate AFOMs including analytical SEN (γ), selectivity (SEL) and limit of detection (LOD) are calculated. Also, two frequently used second- and third-order calibration algorithms of multivariate curve resolution-alternating least squares (MCR-ALS) as representative of multi-set methods and parallel factor analysis (PARAFAC) as representative of multi-way methods are discussed to exploit pure component profiles and to calculate multivariate AFOMs...
September 30, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27594573/phosphorus-recovery-from-biogas-slurry-by-ultrasound-h2o2-digestion-coupled-with-hfo-biochar-adsorption-process
#17
Xuemeng He, Tao Zhang, Hongqiang Ren, Guoxue Li, Lili Ding, Lucjan Pawlowski
Phosphorus (P) recovery from biogas slurry has recently attracted considerable interest. In this work, ultrasound/H2O2 digestion coupled with ferric oxide hydrate/biochar (HFO/biochar) adsorption process was performed to promote P dissolution, release, and recovery from biogas slurry. The results showed that the optimal total phosphorus release efficiency was achieved at an inorganic phosphorus/total phosphorus ratio of 95.0% at pH 4, 1mL of added H2O2, and ultrasonication for 30min. The P adsorption by the HFO/biochar followed pseudo second-order kinetics and was mainly controlled by chemical processes...
September 1, 2016: Waste Management
https://www.readbyqxmd.com/read/27581993/synchronized-mechanical-ventilation-for-respiratory-support-in-newborn-infants
#18
Anne Greenough, Thomas E Rossor, Adesh Sundaresan, Vadivelam Murthy, Anthony D Milner
BACKGROUND: During synchronised mechanical ventilation, positive airway pressure and spontaneous inspiration coincide. If synchronous ventilation is provoked, adequate gas exchange should be achieved at lower peak airway pressures, potentially reducing baro/volutrauma, air leak and bronchopulmonary dysplasia. Synchronous ventilation can potentially be achieved by manipulation of rate and inspiratory time during conventional ventilation and employment of patient-triggered ventilation. OBJECTIVES: To compare the efficacy of:(i) synchronised mechanical ventilation, delivered as high-frequency positive pressure ventilation (HFPPV) or patient-triggered ventilation (assist control ventilation (ACV) and synchronous intermittent mandatory ventilation (SIMV)), with conventional ventilation or high-frequency oscillation (HFO);(ii) different types of triggered ventilation (ACV, SIMV, pressure-regulated volume control ventilation (PRVCV), SIMV with pressure support (PS) and pressure support ventilation (PSV))...
September 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27579546/scalp-recorded-high-frequency-oscillations-in-atypical-benign-partial-epilepsy
#19
Ping Qian, Hui Li, Jiao Xue, Zhixian Yang
OBJECTIVE: To investigate how high-frequency oscillations (HFOs) were affected by methylprednisolone treatment and the clinical significance of HFOs in patients with atypical benign partial epilepsy (ABPE). METHODS: In 14 ABPE patients with methylprednisolone treatment, we measured interictal HFOs and spikes during sleep in pre- and post-methylprednisolone scalp electroencephalography (EEG). Patients with benign childhood epilepsy with centrotemporal spikes (BECTS) were taken as control...
October 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27543302/vildagliptin-reduces-cardiac-ischemic-reperfusion-injury-in-obese-orchiectomized-rats
#20
Wanpitak Pongkan, Hiranya Pintana, Thidarat Jaiwongkam, Sasiwan Kredphoo, Sivaporn Sivasinprasasn, Siriporn C Chattipakorn, Nipon Chattipakorn
Obesity and testosterone deprivation are associated with coronary artery disease. Testosterone and vildagliptin (dipeptidyl peptidase-4 inhibitors) exert cardioprotection during ischemic-reperfusion (I/R) injury. However, the effect of these drugs on I/R heart in a testosterone-deprived, obese, insulin-resistant model is unclear. This study investigated the effects of testosterone and vildagliptin on cardiac function, arrhythmias and the infarct size in I/R heart of testosterone-deprived rats with obese insulin resistance...
October 2016: Journal of Endocrinology
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