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Rachel L Loewy, Sarah Corey, Felix Amirfathi, Sawsan Dabit, Daniel Fulford, Rahel Pearson, Jessica P Y Hua, Danielle Schlosser, Barbara K Stuart, Daniel H Mathalon, Sophia Vinogradov
As a risk factor for psychosis, childhood trauma rates are elevated in the clinical-high-risk (CHR) syndrome compared to the general population. However, it is unknown whether trauma is typically experienced in childhood or adolescence/young adulthood, whether it occurred prior to CHR syndrome onset, and how severe trauma relates to presenting symptoms. In this study, we examined the relationship of trauma history to symptoms and functioning in individuals diagnosed with the CHR syndrome on the Structured Interview for Psychosis-Risk Syndromes (N = 103)...
May 18, 2018: Schizophrenia Research
José R López-Mínguez, Juan M Nogales-Asensio, Eduardo Infante De Oliveira, Vasco De Gama Ribeiro, Rafael Ruiz-Salmerón, Dabit Arzamendi-Aizpurua, Marco Costa, Hipólito Gutiérrez-García, José Antonio Fernández-Díaz, Victoria Martín-Yuste, Juan Carlos Rama-Merchán, Raúl Moreno-Gómez, Amparo Benedicto-Buendía, Andrés Íñiguez-Romo
INTRODUCTION AND OBJECTIVES: Many patients with nonvalvular atrial fibrillation are still left without protection due to a contraindication for anticoagulants. This study aimed to establish the occurrence of stroke and major bleeding events in patients with nonvalvular atrial fibrillation and left atrial appendage closure with long-term follow-up and to explore the factors associated with higher long-term mortality. METHODS: Analysis of a multicenter single cohort prospectively recruited from 2009 to 2015...
May 10, 2018: Revista Española de Cardiología
Thomas VanVleet, Michelle Voss, Sawsan Dabit, Alex Mitko, Joseph DeGutis
BACKGROUND: Healthy aging is associated with a decline in multiple functional domains including perception, attention, short and long-term memory, reasoning, decision-making, as well as cognitive and motor control functions; all of which are significantly modulated by an individual's level of alertness. The control of alertness also significantly declines with age and contributes to increased lapses of attention in everyday life, ranging from minor memory slips to a lack of vigilance and increased risk of falls or motor-vehicle accidents...
May 3, 2018: BMC Psychology
Miquel Vives-Borrás, Esther Jorge, Gerard Amorós-Figueras, Xavier Millán, Dabit Arzamendi, Juan Cinca
Simultaneous ischemia in two myocardial regions is a potentially lethal clinical condition often unrecognized whose corresponding electrocardiographic (ECG) patterns have not yet been characterized. Thus, this study aimed to determine the QRS complex and ST-segment changes induced by concurrent ischemia in different myocardial regions elicited by combined double occlusion of the three main coronary arteries. For this purpose, 12 swine were randomized to combination of 5-min single and double coronary artery occlusion: Group 1: left Circumflex (LCX) and right (RCA) coronary arteries ( n = 4); Group 2: left anterior descending artery (LAD) and LCX ( n = 4) and; Group 3: LAD and RCA ( n = 4)...
2018: Frontiers in Physiology
Leonardo Danduch, Xavier Millan, Chi-Hion Li, Dabit Arzamendi
No abstract text is available yet for this article.
February 2, 2018: EuroIntervention
Xavier Freixa, Rodrigo Estévez-Loureiro, Fernando Carrasco-Chinchilla, Dabit Arzamendi, Pilar Jiménez-Quevedo, Luis Nombela-Franco, Ignacio Cruz-González, Ignacio J Amat-Santos, Manel Sabaté
BACKGROUND: Atrial fibrillation is present in 30-50% of patients undergoing percutaneous mitral valve repair. The presence of a formal contraindication to oral anticoagulation is also very common in these patients. In this context, percutaneous left atrial appendage occlusion (LAAO) may be a valid alternative for these patients. The study aim was to assess the feasibility, safety, and technical considerations of the combination of percutaneous mitral valve repair using the MitraClip system and LAAO...
March 2017: Journal of Heart Valve Disease
Rodrigo Estévez-Loureiro, Xavier Freixa, Dabit Arzamendi, Armando Perez de Prado, Rui Campante-Teles, Bruno Melica, Giuseppe Tarantini, Giuseppe Musumeci, Manuel Pan
Mitral regurgitation is a common valvular heart disease and its prevalence is expected to increase with population ageing. In the recent years we have witnessed the evolution of several transcatheter devices to correct mitral regurgitation in patients at high-risk for surgery. Most of the evidence of the safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives have emerged with promising results. The aim of this position paper is to review the current evidence regarding patient selection, expected results and timing for transcatheter mitral valve interventions from the perspective of three European interventional societies...
September 15, 2017: International Journal of Cardiology
Livia Luciana Gheorghe, Dabit Arzamendi, Chi Hion Li, Antonio J Barros-Membrilla, Jaime Felix Dilme Muñoz, Antonio Serra Peñaranda, Sherif Sultan, Mark S Spence, Anton Collins
No abstract text is available yet for this article.
March 20, 2017: EuroIntervention
Fernando Carrasco-Chinchilla, Rodrigo Estévez-Loureiro, Leire Andraka, Dabit Arzamendi, Xavier Freixa, José Suárez de Lezo
No abstract text is available yet for this article.
December 2017: Revista Española de Cardiología
P U Bassi, A I Osakwe, C Suku, M Kalat, C Elagbaje, A Isah, S Ayinbuomwan, R D Wammanda, I I Bob-Okon, J Ambe, Y Mava, A O Adesina, C G Ugochukwu, E E Nyong, O O Ogunleye, F Onuoha, I Jalo, V O Adegoke, S T Balogun, G Ntadom, F N Ejiekpe, R Tahir, K Dabit, A A Amodu, S Nwaosu, A T Habib
AIMS AND OBJECTIVES: The study was designed with the broad objective of determining the safety profile of artemisinin-based combination therapies amongst Nigerian population. PATIENTS AND METHODS: This was a cohort event monitoring (CEM) programme involving monitoring adverse events (AEs) in malaria patients treated with either artemether-lumefantrine (AL) or artesunate-amodiaquine (AA) in healthcare facilities in Nigeria. The study involved continuous enrolment of patients with malaria and treated with either AL or AA at the various sites until a total cohort of 600 patients were enrolled at each site...
October 2016: Nigerian Postgraduate Medical Journal
Marco Hernández-Enriquez, Rut Andrea, Salvatore Brugaletta, Pilar Jiménez-Quevedo, José María Hernández-García, Ramiro Trillo, Mariano Larman, Francisco Fernández-Avilés, Nicolás Vázquez-González, Andrés Iñiguez, Javier Zueco, Rafael Ruiz-Salmerón, Raquel Del Valle, Eduardo Molina, Bruno García Del Blanco, Alberto Berenguer, Mariano Valdés, Raúl Moreno, Cristóbal Urbano-Carrillo, Rosana Hernández-Antolín, Federico Gimeno, Ángel Cequier, Ignacio Cruz, José Ramón López-Mínguez, José Ignacio Aramendi, Ángel Sánchez, Javier Goicolea, Agustín Albarrán, José Francisco Díaz, Felipe Navarro, José Moreu, Andrés Morist, Eduard Fernández-Nofrerías, Felipe Fernández-Vázquez, Francisco Ten, Vicente Mainar, Belén Mari, Alberto Saenz, Fernando Alfonso, José Antonio Diarte, Manuel Sancho, Román Lezáun, Dabit Arzamendi, Manel Sabaté
Vascular complications in transcatheter aortic valve implantation using transfemoral approach are related to higher mortality. Complete percutaneous approach is currently the preferred technique for vascular access. However, some centers still perform surgical cutdown. Our purpose was to determine complications related to vascular access technique in the population of the Spanish TAVI National Registry. From January 2010 to July 2015, 3,046 patients were included in this Registry. Of them, 2,465 underwent transfemoral approach and were treated with either surgical cutdown and closure (cutdown group, n = 632) or percutaneous approach (puncture group, n = 1,833)...
August 15, 2016: American Journal of Cardiology
Thomas M Van Vleet, Joseph M DeGutis, Michael M Merzenich, Gregory V Simpson, Ativ Zomet, Sawsan Dabit
Efficient self-regulation of alertness declines with age exacerbating normal declines in performance across multiple cognitive domains, including learning and skill acquisition. Previous cognitive intervention studies have shown that it is possible to enhance alertness in patients with acquired brain injury and marked attention impairments, and that this benefit generalizes to improvements in more global cognitive functions. In the current preliminary studies, we sought to test whether this approach, that targets both tonic (over a period of minutes) and phasic (moment-to-moment) alertness, can improve key executive functioning declines in older adults, and enhance the rate of skill acquisition...
September 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Apostolos Tzikas, Sameer Gafoor, David Meerkin, Xavier Freixa, Ignacio Cruz-Gonzalez, Thorsten Lewalter, Jacqueline Saw, Sergio Berti, Jens Erik Nielsen-Kudsk, Reda Ibrahim, Dhanunjaya Lakkireddy, Vincent Paul, Dabit Arzamendi, Fabian Nietlispach, Stephen G Worthley, David Hildick-Smith, Jean Benoit Thambo, Claudio Tondo, Adel Aminian, Zbigniew Kalarus, Boris Schmidt, Lars Sondergaard, Joelle Kefer, Bernhard Meier, Jai-Wun Park, Horst Sievert, Heyder Omran
AIMS: This document aims to describe a standardised methodology for performing left atrial appendage occlusion (LAAO) using the AMPLATZER Amulet device, and to provide useful tips and tricks for operators with different levels of experience. METHODS AND RESULTS: Physicians who are experts in LAAO and had personal clinical experience with the AMPLATZER Amulet device were asked to contribute in the preparation of this consensus document. Twenty-seven physicians (20 interventional cardiologists and 7 electrophysiologists) from 14 different countries reviewed the manuscript...
April 20, 2016: EuroIntervention
Rodrigo Estévez-Loureiro, Dabit Arzamendi, Fernando Carrasco-Chinchilla, Ignacio J Amat-Santos, Xavier Freixa, José Suárez de Lezo
No abstract text is available yet for this article.
April 2016: Revista Española de Cardiología
Chi-Hion Li, Dabit Arzamendi, Francesc Carreras
Mitral regurgitation is the most prevalent valvular heart disease in the United States and the second most prevalent in Europe. Patients with severe mitral regurgitation have a poor prognosis with medical therapy once they become symptomatic or develop signs of significant cardiac dysfunction. However, as many as half of these patients are inoperable because of advanced age, ventricular dysfunction, or other comorbidities. Studies have shown that surgery increases survival in patients with organic mitral regurgitation due to valve prolapse but has no clinical benefit in those with functional mitral regurgitation...
April 2016: Revista Española de Cardiología
Konstantinos Marmagkiolis, Dabit Arzamendi, Omer Goktekin, Mehmet Cilingiroglu
BACKGROUND: Structural heart interventions have made major strides over the last years with the introduction of TAVR, percutaneous mitral valve repair and adult congenital heart disease procedures. METHODS: As part of the SCAI SHD Early Career Task Force committee, we complied a survey of 17 questions using a Survey Monkey website. We sent invitations twice by email to 183 European program directors of interventional cardiology fellowship programs in Europe. RESULTS: The most commonly performed procedures performed by the fellows were transseptal punctures, TAVR, BAV, PFO and BMV...
January 1, 2016: International Journal of Cardiology
Emmanuel Ademola Anigilaje, Joseph Othniel Dabit, Nnamdi Okechukwu Nweke, Augustine Aondohemba Agbedeh
INTRODUCTION: Cytomegalovirus (CMV) co-infection increases morbidity and mortality in human immunodeficiency virus (HIV) disease. There has been no study on CMV infection and its risk factors among Nigerian HIV-infected and/or HIV-exposed uninfected infants. METHODOLOGY: This was a cross-sectional cohort study at the Federal Medical Center, Makurdi, between January 2012 and March 2013. Acute CMV infection among consecutive three-month- old HIV-infected and HIV-exposed uninfected infants was determined using the enzyme-linked immunosorbent assay of the CMV immunoglobulin M (IgM)...
September 2015: Journal of Infection in Developing Countries
Emmanuel A Anígilájé, Othniel J Dabit, Ayodotun Olutola, Bem Ageda, Sunday A Aderibigbe
BACKGROUND: In Nigeria, reports of the outcomes of prevention of mother to child transmission of HIV (PMTCT) interventions had been limited to the MTCT rates of HIV, with no information on HIV-free survival (HFS) in the HIV-exposed infants over time. METHODS: A retrospective study between June 2008 and December 2011 at the Federal Medical Centre, Makurdi, Nigeria comparing HFS rates at 3 and 18 months according to the infant feeding pattern at the 6th week of life...
2015: BMC Infectious Diseases
Xavier Millán, Sabah Skaf, Lawrence Joseph, Carlos Ruiz, Eulogio García, Grzegorz Smolka, Stéphane Noble, Ignacio Cruz-González, Dabit Arzamendi, Antoni Serra, Chad Kliger, Ying Tung Sia, Anita Asgar, Réda Ibrahim, E Marc Jolicœur
BACKGROUND: Significant paravalvular leak (PVL) after surgical valve replacement can result in intractable congestive heart failure and hemolytic anemia. Because repeat surgery is performed in only few patients, transcatheter reduction of PVL is emerging as an alternative option, but its safety and efficacy remain uncertain. In this study we sought to assess whether a successful transcatheter PVL reduction is associated with an improvement in clinical outcomes. METHODS: We identified 12 clinical studies that compared successful and failed transcatheter PVL reductions in a total of 362 patients...
March 2015: Canadian Journal of Cardiology
Dabit Arzamendi, Chi Hion Li, Antoni Serra
No abstract text is available yet for this article.
July 2015: Revista Española de Cardiología
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