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Spinal cord injury israel

E Aidinoff, V Bluvshtein, U Bierman, I Gelernter, L Front, A Catz
STUDY DESIGN: Retrospective observational comparative study. OBJECTIVES: The objectives of this study were to assess the atherosclerosis diseases and risk factors prevalence after spinal cored injury (SCI). SETTING: Loewenstein Rehabilitation Hospital, Israel. METHODS: Data of 154 traumatic and non-traumatic SCI patients were retrospectively collected. Coronary artery disease (CAD), myocardial infarction (MI), hypertension (HT) and risk factors for atherosclerotic diseases were examined after SCI for prevalence and effects, and compared with published corresponding data of the general population...
July 19, 2016: Spinal Cord
Vinnitsa Buzoianu-Anguiano, Sandra Orozco-Suárez, Elisa García-Vences, Sara Caballero-Chacón, Gabriel Guizar-Sahagún, Luis Chavez-Sanchez, Israel Grijalva
Functional recovery following spinal cord injury (SCI) is limited by poor axonal and cellular regeneration as well as the failure to replace damaged myelin. Employed separately, both the transplantation of the predegenerated peripheral nerve (PPN) and the transplantation of bone marrow stromal cells (BMSCs) have been shown to promote the regrowth and remyelination of the damaged central axons in SCI models of hemisection, transection, and contusion injury. With the aim to test the effects of the combined transplantation of PPN and BMSC on regrowth, remyelination, and locomotor function in an adult rat model of spinal cord (SC) transection, 39 Fischer 344 rats underwent SC transection at T9 level...
2015: Neural Plasticity
Jacqueline S Israel, Anna R Carlson, Laura A Bonneau, Steve J Kempton, Timothy W King, Michael L Bentz, Ahmed M Afifi
BACKGROUND: Patients with spinal cord injury (SCI) requiring reconstructive surgery, particularly for pressure ulcers, are ubiquitous in Plastic and Reconstructive Surgery practices. Much of the current literature focuses on operative techniques, antibiotic indications, sitting protocols, and dressing and bedding choices. METHODS: This paper reviews normal neuroanatomy, outlines changes in neurophysiology observed in spinal cord injury, and addresses concepts related to perioperative care that are highly relevant but often under-emphasised...
2016: Journal of Plastic Surgery and Hand Surgery
Ian Benson, Kirsten Hart, Dot Tussler, Joost J van Middendorp
OBJECTIVE: To assess the feasibility of conducting a well-powered trial evaluating the neurological and functional effects of using an exoskeleton in individuals with chronic spinal cord injury. DESIGN: A longitudinal, prospective, self-controlled feasibility study. SETTING: Specialist Spinal Cord Injuries Centre, UK; 8 months during 2013-2014. SUBJECTS: Individuals with chronic motor complete or incomplete spinal cord injury...
January 2016: Clinical Rehabilitation
Giorgio Scivoletto, Clive Glass, Kim D Anderson, Tal Galili, Yoav Benjamin, Lilach Front, Elena Aidinoff, Vadim Bluvshtein, Malka Itzkovich, Sergio Aito, Ilaria Baroncini, Jesùs Benito-Penalva, Simona Castellano, Aheed Osman, Pedro Silva, Amiram Catz
Background. A quadratic formula of the Spinal Cord Injury Ability Realization Measurement Index (SCI-ARMI) has previously been published. This formula was based on a model of Spinal Cord Independence Measure (SCIM95), the 95th percentile of the SCIM III values, which correspond with the American Spinal Injury Association Motor Scores (AMS) of SCI patients. Objective. To further develop the original formula. Setting. Spinal cord injury centers from 6 countries and the Statistical Laboratory, Tel-Aviv University, Israel...
January 2015: Neurorehabilitation and Neural Repair
Chanan Tauber
In early mandatory Israel, orthopedics was mainly conservative, The first modern orthopedic surgeon was Ernst Spira from Czechoslovakia who established an orthopedic service at the Beilinson Hospital in Petah Tikva and left in 1948 to establish the Orthopedic Department and the Rehabilitation Center in Tel Hashomer, which treated the War of Independence casualties including amputees and victims of spinal cord injuries. A second orthopedic department was opened in Tel Hashomer by Shmuel Weissman who left in 1961 to open the Orthopedic Department at the Ichilov hospital in Tel Aviv...
August 2013: Harefuah
Dielise D Iucksch, Vera L Israel, Danieli I R Ribas, Elisangela F Manffra
OBJECTIVE: To describe the kinematic gait characteristics of individuals with incomplete chronic spinal cord injury in a water environment and to compare these characteristics with those of healthy individuals. DESIGN: Cross-sectional study. SUBJECTS: Nineteen adults divided into 2 groups: individuals (n = 9) with incomplete chronic spinal cord injury (> 1 year), American Spinal Injury Association Impairment Scale (AIS) C or D; and a second group (n = 10) of healthy young adults...
September 2013: Journal of Rehabilitation Medicine
Horacio J Reyes-Alva, Rebecca E Franco-Bourland, Angelina Martinez-Cruz, Israel Grijalva, Ignacio Madrazo, Gabriel Guizar-Sahagun
Spontaneous repair or treatment-induced recovery after spinal cord injury (SCI) is very limited and might be related to extramedullary alterations that have only briefly been documented. Here we report on the morphological changes of the spinal subarachnoid space (SAS) in a clinically relevant model of SCI. Anesthetized rats were subjected either to mild or severe spinal cord contusion at T9. Spine blocks from the site of injury and adjacent segments were harvested at acute (1 h and 1 day [d]), subacute (3 and 7 d), and chronic (1 and 3 months) stages post-injury...
June 15, 2013: Journal of Neurotrauma
S Geyh, C Ballert, A Sinnott, S Charlifue, A Catz, J M D'Andrea Greve, M W M Post
STUDY DESIGN: An international cross-sectional study. OBJECTIVE: To examine the quality of life (QoL) of people with spinal cord injury (SCI) across six countries worldwide, controlling for socio-demographic and lesion-related sample characteristics and using a cross-culturally valid assessment. METHODS: Data from 243 persons with SCI from Australia, Brazil, Canada, Israel, South Africa and the United States were analyzed. QoL was measured using five satisfaction items from the World Health Organization Quality of Life Assessment...
April 2013: Spinal Cord
Kayode Israel Oke, Oluwaseun S Kubeyinje, Elias O Agwubike
Spinal cord injury is a life-transforming condition of sudden onset that can have devastating consequences. A multidisciplinary, functional goal-oriented programme is required to enable the tetraplegic patient live as fully and independently life as possible. Physiotherapy is a very important part of the multidisciplinary team required to prevent many of the immobilization complications that may result in serious functional limitations, reduce overall morbidity and achieve well patterned recovery. This study therefore highlights the neuromuscular adaptations of tetraplegic patients to physiotherapy over a period of six weeks...
September 2012: Global Journal of Health Science
D P Lammertse, L A T Jones, S B Charlifue, S C Kirshblum, D F Apple, K T Ragnarsson, S P Falci, R F Heary, T F Choudhri, A L Jenkins, R R Betz, D Poonian, J P Cuthbert, A Jha, D A Snyder, N Knoller
STUDY DESIGN: Randomized controlled trial with single-blinded primary outcome assessment. OBJECTIVES: To determine the efficacy and safety of autologous incubated macrophage treatment for improving neurological outcome in patients with acute, complete spinal cord injury (SCI). SETTING: Six SCI treatment centers in the United States and Israel. METHODS: Participants with traumatic complete SCI between C5 motor and T11 neurological levels who could receive macrophage therapy within 14 days of injury were randomly assigned in a 2:1 ratio to the treatment (autologous incubated macrophages) or control (standard of care) groups...
September 2012: Spinal Cord
Itai Gat, Ettie Maman, Gil Yerushalmi, Micha Baum, Jehoshua Dor, Gil Raviv, Igal Madjar, Ariel Hourvitz
OBJECTIVE: To evaluate sperm quality and fertility potential of men with psychogenic anejaculation treated by electroejaculation (EEJ) and intracytoplasmic sperm injection (ICSI). Treatment results were compared to spinal cord injured (SCI) patients treated similarly. DESIGN: Retrospective clinical study. SETTING: Academic tertiary referral fertility center. PATIENT(S): Couples with isolated psychogenic anejaculation or SCI...
May 2012: Fertility and Sterility
Gabi Zeilig, Harold Weingarden, Manuel Zwecker, Israel Dudkiewicz, Ayala Bloch, Alberto Esquenazi
OBJECTIVES: The objective of the study was to evaluate the safety and tolerance of use of the ReWalk™ exoskeleton ambulation system in people with spinal cord injury. Measures of functional ambulation were also assessed and correlated to neurological spinal cord level, age, and duration since injury. STUDY DESIGN: Case series observational study. SETTING: A national spinal cord injury centre. METHODS: Six volunteer participants were recruited from the follow-up outpatient clinic...
March 2012: Journal of Spinal Cord Medicine
E Aidinoff, Y Benjamini, T Galili, T Polliack, L Front, V Bluvshtein, M Itzkovich, J Hart, A Catz
STUDY DESIGN: The spinal cord injury ability realization measurement index (SCI-ARMI) assesses rehabilitation potential and efficacy based on the linear relationship between the Spinal Cord Independence Measure (SCIM) and the American Spinal Injury Association impairment scale (AIS) motor scores (AMS). OBJECTIVES: The objective of this study is to develop new SCI-ARMI formulas using a more flexible approach that is less sensitive to the distribution of the AMS score among spinal cord lesion (SCL) patients...
April 2012: Spinal Cord
Gabriel Guízar-Sahagún, Israel Grijalva, Braulio Hernández-Godínez, Rebecca E Franco-Bourland, Leticia Cruz-Antonio, Angelina Martínez-Cruz, Alejandra Ibáñez-Contreras, Ignacio Madrazo
BACKGROUND: Current models of spinal cord injury (SCI) have been ineffective for translational research. Primate blunt SCI, which more closely resembles human injury, could be a promising model to fill this gap. METHODS: Graded compression SCI was produced by inflating at T9 an epidural balloon as a function of spinal canal dimensions in a non-uniform group of monkeys. RESULTS: Sham injury and cord compression by canal invasion of 50-75% produced minimal morpho-functional alterations, if at all...
December 2011: Journal of Medical Primatology
Israel Grijalva, Angélica García-Pérez, Jenaro Díaz, Sergio Aguilar, Dolores Mino, Efraín Santiago-Rodríguez, Gabriel Guizar-Sahagún, Gilberto Castañeda-Hernández, Héctor Maldonado-Julián, Ignacio Madrazo
BACKGROUND AND AIMS: Many patients with complete spinal cord injury (SCI) exhibit demyelinated and poorly myelinated nerve fibers traversing the lesion site. Conventional doses of 4-aminopyridine (4-AP, 30 mg/day) have shown to provide no or minor functional improvement in these patients. We undertook this study to test the functional effect of high doses of 4-AP on patients with chronic complete SCI with cord continuity at the site of injury demonstrated by magnetic resonance imaging...
October 2010: Archives of Medical Research
Szilvia Geyh, Bernd A G Fellinghauer, Inge Kirchberger, Marcel W M Post
BACKGROUND: Quality of life (QoL) in persons with spinal cord injury (SCI) has been found to differ across countries. However, comparability of measurement results between countries depends on the cross-cultural validity of the applied instruments. The study examined the metric quality and cross-cultural validity of the Satisfaction with Life Scale (SWLS), the Life Satisfaction Questionnaire (LISAT-9), the Personal Well-Being Index (PWI) and the 5-item World Health Organization Quality of Life Assessment (WHOQoL-5) across six countries in a sample of persons with spinal cord injury (SCI)...
2010: Health and Quality of Life Outcomes
L A T Jones, D P Lammertse, S B Charlifue, S C Kirshblum, D F Apple, K T Ragnarsson, D Poonian, R R Betz, N Knoller, R F Heary, T F Choudhri, A L Jenkins, S P Falci, D A Snyder
STUDY DESIGN: Post hoc analysis from a randomized controlled cellular therapy trial in acute, complete spinal cord injury (SCI). OBJECTIVES: Description and quantitative review of study logistics, referral patterns, current practice patterns and subject demographics. SETTING: Subjects were recruited to one of six international study centers. METHODS: Data are presented from 1816 patients pre-screened, 75 participants screened and 50 randomized...
November 2010: Spinal Cord
G Zeilig, H P Weingarden, M Zwecker, D Rubin-Asher, A Ratner, A Ohry
STUDY DESIGN: Retrospective analysis of civilians with spinal cord injuries (SCIs) due to terror explosions. OBJECTIVES: To analyze and describe the clinical characteristics and rehabilitation outcomes of civilians with SCI due to explosions admitted for in-patient rehabilitation from 2000-2004. SETTING: SCI rehabilitation service, Tel Hashomer, Israel. METHODS: Retrospective chart review. Civilians with SCI due to terror-related gunshot wounds (GSWs) served as a control group...
November 2010: Spinal Cord
Horacio J Reyes-Alva, Rebecca E Franco-Bourland, Angelina Martínez-Cruz, Israel Grijalva, Bruno Fuchs, Ignacio Madrazo, Gabriel Guízar-Sahagún
Mechanical damage to the spinal cord (SC) generates self-destructive processes that contribute to post-traumatic neurodegeneration. Because thalidomide apparently counteracts these effects its use clinically has been proposed enthusiastically. Nonetheless, we tested its action as a neuroprotectant in a clinically relevant model of SC injury in rats. We administered thalidomide intraperitoneally to rats subjected to thoracic SC contusion as single or repeated doses within the first 24 h after injury. Edema, neutrophil infiltration, and cord tissue preservation/destruction were assessed in the SC 24 h after injury and motor function for 7 weeks...
2009: Acta Neurobiologiae Experimentalis
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