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https://www.readbyqxmd.com/read/29035609/single-surgeon-experience-and-complications-of-a-fixed-bearing-total-ankle-arthroplasty
#1
Garett J Pangrazzi, Erin A Baker, Phillip J Shaheen, Chikezie N Okeagu, Paul T Fortin
BACKGROUND: Total ankle arthroplasty (TAA) has historically resulted in inferior survivorship rates compared with total hip and knee arthroplasty, because of technical issues unique to ankle anatomy. In this study, a single-surgeon series of intra- and postoperative complications as well as resultant reoperations/revisions of the Tornier Salto Talaris, a fixed-bearing TAA prosthesis, were reviewed. METHODS: Medical records from index procedure to latest follow-up of primary TAA were reviewed...
October 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29034874/pathogenesis-of-plasmodium-berghei-anka-infection-in-the-gerbil-meriones-unguiculatus-as-an-experimental-model-for-severe-malaria
#2
Quazim Olawale Junaid, Loke Tim Khaw, Rohela Mahmud, Kien Chai Ong, Yee Ling Lau, Prajakta Uttam Borade, Jonathan Wee Kent Liew, Sinnadurai Sivanandam, Kum Thong Wong, Indra Vythilingam
BACKGROUND: As the quest to eradicate malaria continues, there remains a need to gain further understanding of the disease, particularly with regard to pathogenesis. This is facilitated, apart from in vitro and clinical studies, mainly via in vivo mouse model studies. However, there are few studies that have used gerbils (Meriones unguiculatus) as animal models. Thus, this study is aimed at characterizing the effects of Plasmodium berghei ANKA (PbA) infection in gerbils, as well as the underlying pathogenesis...
2017: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/29034133/local-cellular-responses-to-titanium-dioxide-from-orthopedic-implants
#3
REVIEW
Jie J Yao, Eric A Lewallen, William H Trousdale, Wei Xu, Roman Thaler, Christopher G Salib, Nicolas Reina, Matthew P Abdel, David G Lewallen, Andre J van Wijnen
We evaluated recently published articles relevant to the biological effects of titanium dioxide (TiO2) particles on local endogenous cells required for normal bone homeostasis, repair, and implant osseointegration. Structural characteristics, size, stability, and agglomeration of TiO2 particles alter the viability and behavior of multiple bone-related cell types. Resulting shifts in bone homeostasis may increase bone resorption and lead to clinical incidents of osteolysis, implant loosening, and joint pain...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/29033158/revision-total-knee-arthroplasty-for-periprosthetic-joint-infection-is-associated-with-increased-postoperative-morbidity-and-mortality-relative-to-noninfectious-revisions
#4
Venkat Boddapati, Michael C Fu, David J Mayman, Edwin P Su, Peter K Sculco, Alexander S McLawhorn
BACKGROUND: Periprosthetic joint infection (PJI) after primary total knee arthroplasty (TKA) is a devastating complication. The short-term morbidity profile of revision TKA performed for PJI relative to non-PJI revisions is poorly characterized. The purpose of this study is to determine 30-day postoperative outcomes after revision TKA for PJI, relative to primary TKA and aseptic revision TKA. METHODS: The American College of Surgeons National Surgical Quality Improvement Program from 2005 to 2015 was queried for primary and revision TKA cases...
September 23, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29033154/the-use-of-porous-tantalum-augments-for-the-reconstruction-of-acetabular-defect-in-primary-total-hip-arthroplasty
#5
Ting-Xian Ling, Jin-Long Li, Kai Zhou, Qiang Xiao, Fu-Xing Pei, Zong-Ke Zhou
BACKGROUND: Given the lack of studies of acetabular defect reconstruction in primary total hip arthroplasty (THA) using tantalum augments, this study aims to evaluate clinical and radiographic results for treatment with tantalum augments to reconstruct acetabular defects in primary THA. METHODS: We retrospectively reviewed 19 patients (19 hips) with acetabular defects who underwent primary THA using tantalum augments, with a minimum follow-up of 2 years. Clinical, radiographic, and surgical data were retrospectively evaluated...
September 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29031824/the-exeter-trauma-stem-a-radiographic-follow-up-at-minimum-of-five-years-post-implantation
#6
A M Kassam, L Tillotson, S L Whitehouse, J Charity
INTRODUCTION: The Exeter Trauma Stem (ETS) has been recommended by National Institute of Clinical Excellence (NICE) guidelines in the United Kingdom as a proven, cemented stem. A single laboratory study in the literature has raised possible concerns about the polished finish of the ETS and subsequent potential for accelerated loosening although there is little clinical evidence to support or refute this. METHODS: The aim of this study was to assess clinical outcomes of the ETS at a minimum of five years post implantation...
October 7, 2017: Injury
https://www.readbyqxmd.com/read/29030653/lateral-unicompartmental-knee-replacement-a-systematic-review-of-reasons-for-failure
#7
REVIEW
Lukas Ernstbrunner, Mohamed A Imam, Octavian Andronic, Tabea Perz, Karl Wieser, Sandro F Fucentese
PURPOSE: Currently, individual studies lack the power to successively illustrate different failure modes; therefore, we undertook a systematic review to examine lateral unicompartmental knee replacement (lat UKR) failure modes. Furthermore, we compared early with midterm and late failures and fixed-bearing with mobile-bearing implants. METHODS: A search using the databases of PubMed, EMBASE, Cochrane, and annual registries was performed to search for failed lat UKRs...
October 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29027190/midterm-results-of-revision-total-hip-arthroplasty-with-an-uncemented-modular-femoral-component
#8
Bertram Rieger, Thomas Ilchmann, Lilianna Bolliger, Karl K Stoffel, Lukas Zwicky, Martin Clauss
INTRODUCTION: During revision total hip arthroplasty (THA), the surgeon commonly faces deficient proximal femoral bone. In this situation, distal fixation of the prosthesis is required. The aim of the current retrospective study is to assess the clinical and radiographic midterm outcome of revision total hip arthroplasty using a modular uncemented, tapered, grit-blasted, distal straight stem system. METHODS: This retrospective study included 70 femoral revisions that were performed in 67 patients using the device of interest...
October 12, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29025948/genome-sequences-of-coxsackievirus-b5-isolates-from-two-children-with-meningitis-in-australia
#9
Bixing Huang, Bruce Harrower, Peter Burtonclay, Tanya Constantino, David Warrilow
Two coxsackievirus B5 (CVB5) strains were isolated from two children with aseptic meningitis in Australia. Their genomes were sequenced and found to be divergent from the previously reported CVB5 genome sequences, with both having 84% and 97% identities to the closest strains at the nucleotide and amino acid levels, respectively.
October 12, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29025612/clavicle-aseptic-nonunion-is-there-a-place-for-cortical-allogenic-strut-graft
#10
Giuseppe Rollo, Giovanni Vicenti, Roberto Rotini, Antonella Abate, Antonio Colella, Antonio D'Arienzo, Massimiliano Carrozzo, Biagio Moretti
We investigated functional and radiological outcome in 57 cases of midshaft clavicle nonunion treated with open reduction and internal fixation with plate and screws over a 13 year-period. Intercalary bone graft was used in 42 patients; opposite autologous strut graft was used in 31 cases to provide mechanical support to the host bone. Patients were analysed using chart and radiological review and assessed with DASH questionnaire obtained at the latest follow-up. 37 patients were male while 20 were females, with a mean age of 35 years (63-17)...
October 2017: Injury
https://www.readbyqxmd.com/read/29025607/peek-radiolucent-plate-for-distal-radius-fractures-multicentre-clinical-results-at-12-months-follow-up
#11
Bruno Di Maggio, Pasquale Sessa, Patrizia Mantelli, Pietro Maniscalco, Fabrizio Rivera, Giorgio Maria Calori, Luigi Bisogno, Gabriele Scaravilli, Marco Caforio
INTRODUCTION: Open reduction and internal fixation (ORIF) with plate and screws represents the recommended treatment for unstable intra-articular distal radius fractures. Although significant progresses in surgical technique have been made, anatomical reconstruction of radio-carpal articular surface still represent a difficult task, especially in multifragmentary fractures. Available PEEK reinforced-carbon fiber composite radiolucent devices allow both an easier and more careful assessment of intra-operative reduction of the articular surface of distal radius and prompt correction of any residual step deformity...
October 2017: Injury
https://www.readbyqxmd.com/read/29023196/home-parenteral-nutrition-vascular-access-and-related-complications
#12
Martyn Dibb, Simon Lal
Patients with chronic intestinal failure are dependent on parenteral nutrition (PN) to maintain health and preserve life. Maintaining safe vascular access is vital to prevent life-threatening complications such as catheter-related bloodstream infection or central venous occlusion. Dedicated central venous catheters with rigorous catheter care aseptic protocols are vital in obtaining good long-term outcomes that allow continuation of PN over many years. Good catheter care requires an experienced multidisciplinary team using appropriate vascular devices, trained to identify and aggressively treat catheter-related bloodstream infections, catheter occlusions, and catheter-related thrombosis...
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29016434/hypoalbuminemia-is-associated-with-septic-revisions-after-primary-surgery-and-post-operative-infection-after-revision-surgery
#13
Krishn Khanna, Paul H Yi, David C Sing, Erik Geiger, Lionel N Metz
STUDY DESIGN: Retrospective Database Review OBJECTIVE.: To determine (1) the relationship between hypoalbuminemia and body mass index (BMI); (2) the association between malnutrition and revision spine surgery for septic reasons; (3) the association between malnutrition and infection after aseptic revision spine surgery. SUMMARY OF BACKGROUND DATA: Although malnutrition has been suggested to increase the risk of infection after spine surgery, evidence supporting this hypothesis is conflicting...
October 9, 2017: Spine
https://www.readbyqxmd.com/read/29016310/case-report-a-cluster-of-three-leptospirosis-cases-in-a-new-york-city-abattoir-and-an-unusual-complication-in-the-index-case
#14
Tania Kupferman, Megan P Coffee, Benjamin J Eckhardt
We report the case of a 46-year-old man abattoir worker who developed myalgias, shortness of breath, and irritability 2 weeks after sustaining a laceration to the hand with a knife at work. During his hospital evaluation for septic shock he was noted to be febrile, hypotensive, profoundly jaundiced with aseptic meningitis, and renal failure, and was diagnosed with Leptospirosis interrogans infection confirmed by serum and urine polymerase chain reaction. After standard antibiotic therapy and recovery from severe clinical illness, he developed unilateral orchitis with pyuria secondary to leptospirosis, a well-established complication in the veterinary literature, but of which we offer the first report in humans in the English literature...
October 2, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28993899/industrial-antifoam-agents-impair-ethanol-fermentation-and-induce-stress-responses-in-yeast-cells
#15
Jens Christian Nielsen, Felipe Senne de Oliveira Lino, Thomas Gundelund Rasmussen, Jette Thykær, Christopher T Workman, Thiago Olitta Basso
The Brazilian sugarcane industry constitutes one of the biggest and most efficient ethanol production processes in the world. Brazilian ethanol production utilizes a unique process, which includes cell recycling, acid wash, and non-aseptic conditions. Process characteristics, such as extensive CO2 generation, poor quality of raw materials, and frequent contaminations, all lead to excessive foam formation during fermentations, which is treated with antifoam agents (AFA). In this study, we have investigated the impact of industrial AFA treatments on the physiology and transcriptome of the industrial ethanol strain Saccharomyces cerevisiae CAT-1...
October 10, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28993083/acetabular-revision-arthroplasty-using-an-uncemented-deep-profile-jumbo-component-a-ten-to-sixteen-year-follow-up-study
#16
Jeffrey R McLaughlin, Kyla R Lee
BACKGROUND: The purpose of this study is to evaluate the outcome of revision total hip arthroplasty using an uncemented deep profile jumbo acetabular component in patients who had been followed for a minimum of 10 years postoperatively. METHODS: Between 1997 and 2001, 61 revision total hip arthroplasties were performed in 58 patients, with use of the +5 Deep Profile acetabular shell. The outcome with regard to retention vs re-revision of the acetabular component was determined for every hip...
September 14, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28993082/noncemented-total-hip-arthroplasty-in-sickle-cell-disease-long-term-results
#17
Imran Ilyas, Husam A Alrumaih, Samar Rabbani
BACKGROUND: Avascular necrosis of the femoral head is a well-known sequela of sickle-cell disease (SCD) requiring a surgical intervention that comes with technical challenges. METHODS: Uncemented hip arthroplasty for avascular necrosis of the femoral head due to SCD was carried out for 101 patients (133 hips) between 2000 and 2012. The duration of follow-up ranged from 5 to 17 years (mean, 14.59 years). All patients received a noncemented femoral stem and a noncemented acetabular shell...
September 14, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28992376/technologies-of-cryoprotectant-free-vitrification-of-human-spermatozoa-asepticity-as-criterion-of-effectiveness
#18
REVIEW
V Isachenko, G Rahimi, P Mallmann, R Sanchez, E Isachenko
This review describes 120 years history of technology for cryoprotectant-free cryopreservation of human spermatozoa by direct plunging into liquid nitrogen (vitrification). It is presented an explanation why cryoprotectant-free vitrification for some human ejaculates is better than conventional freezing and vitrification with the presence of cryoprotectants. Special attention is given to the extremely high viability of viruses, bacteria and micoplasmas after cryoprotectant-free cryopreservation in culture medium and even in distilled water...
October 9, 2017: Andrology
https://www.readbyqxmd.com/read/28990090/calcineurin-nfat-signaling-pathway-mediates-titanium-particle%C3%A2-induced-inflammation-and-osteoclast-formation-by-inhibiting-rankl-and-m%C3%A2-csf-in%C3%A2-vitro
#19
Yunge Zhang, Peng Jiang, Wenbo Li, Xiangjie Liu, Yang Lu, Zhipeng Huang, Keguan Song
Wear particles serve a central role in periprosthetic osteolysis, which leads to the aseptic loosening of prostheses. In the present study a lentiviral vector was constructed to silence macrophage colony stimulating factor (M‑CSF) and receptor activator of nuclear factor κ‑B ligand (RANKL) genes, which synergistically inhibit osteoclast formation and differentiation. To confirm the role of the calcineurin/nuclear factor of activated T cells (NFAT) pathway in osteolysis, we transduced murine macrophage/monocyte RAW264...
September 29, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28989875/bacteriological-profile-of-diabetic-foot-ulcer-with-special-reference-to-drug-resistant-strains-in-a-tertiary-care-center-in-north-east-india
#20
Sudhir K Jain, Rashmisnata Barman
AIM: This study was carried out to determine the bacteriological profile of infected diabetic foot ulcers (DFUs) and the antibiotic resistance pattern from the isolates. An attempt was made to suggest an empiric antibiotic regimen to treat such patients. MATERIALS AND METHODS: Tissue samples were collected from 150 patients between February 2015 and January 2016 with DFUs under aseptic precautions and they were processed as per the Clinical and Laboratory Standards Institute guidelines...
September 2017: Indian Journal of Endocrinology and Metabolism
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