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https://www.readbyqxmd.com/read/28545196/comparison-of-cox-regression-and-parametric-models-application-for-assessment-of-survival-of-pediatric-cases-of-acute-leukemia-in-southern-iran
#1
Saeed Hosseini Teshnizi, Seyyed Mohammad Taghi Ayatollahi
Background: Finding the most appropriate regression model for survival data in cancer casesin order to determine prognosis is an important issue in medical research. Here we compare Cox and parametric regression models regarding survival of children with acute leukemia in southern Iran. Methods: In a retrospective cohort study, information for 197 children with acute leukemia over 6 years was collected through observation and interviews. In order to identify factors affecting their survival, the Cox and parametric (exponential, Weibull, log-logistic, log-normal, Gompertz and generalized gamma) models were fitted to the data...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28537021/life-cycle-energy-use-costs-and-greenhouse-gas-emission-of-broiler-farms-in-different-production-systems-in-iran-a-case-study-of-alborz-province
#2
Seyyed Hassan Pishgar-Komleh, Asadollah Akram, Alireza Keyhani, Rosalie van Zelm
In order to achieve sustainable development in agriculture, it is necessary to quantify and compare the energy, economic, and environmental aspects of products. This paper studied the energy, economic, and greenhouse gas (GHG) emission patterns in broiler chicken farms in the Alborz province of Iran. We studied the effect of the broiler farm size as different production systems on the energy, economic, and environmental indices. Energy use efficiency (EUE) and benefit-cost ratio (BCR) were 0.16 and 1.11, respectively...
May 23, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28529944/optimization-of-time-for-neural-stem-cells-transplantation-for-brain-stroke-in-rats
#3
Seyyed Mohyeddin Ziaee, Parisa Tabeshmehr, Khawaja Husnain Haider, Majidreza Farrokhi, Abdolhamid Shariat, Atena Amiri, Seyed Mojtaba Hosseini
BACKGROUND: Despite encouraging data in terms of neurological outcome, stem cell based therapy for ischemic stroke in experimental models and human patients is still hampered by multiple as yet un-optimized variables, i.e., time of intervention, that significantly influence the prognosis. The aim of the present study was to delineate the optimum time for neural stem cells (NSCs) transplantation after ischemic stroke. METHODS: The NSCs were isolated from 14 days embryo rat ganglion eminence and were cultured in NSA medium (neurobasal medium, 2% B27, 1% N2, bFGF 10 ng/mL, EGF 20 ng/mL and 1% pen/strep)...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28521282/the-possibility-of-using-c20-fullerene-and-graphene-as-semiconductor-segments-for-detection-and-destruction-of-cyanogen-chloride-chemical-agent
#4
Parvaneh Pakravan, Seyyed Amir Siadati
Detection of hazardous chemical species by changing the electrical conductivity of a semiconductor matter is a proposed and applied way for decreasing their subsequent unpleasant effects. Recently, many examples of using inorganic or organic materials, polymeric, and also nano-sized species as sensors were reported in which, in some cases, those matters were strongly affective and suitable. In this project, we have made an assessment on whether the graphene segment or C20 fullerene, able to sense the existence of cyanogen chloride NCCl? In order to gain trustable results, the possible reaction pathways along with the adsorption kinetics were investigated...
April 27, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28520586/clinical-course-of-ulcerative-colitis-after-liver-transplantation-in-patients-with-concomitant-primary-sclerosing-cholangitis-and-ulcerative-colitis
#5
Mohammad Reza Fattahi, Seyyed Ali Malek-Hosseini, Gholam Reza Sivandzadeh, Ali Reza Safarpour, Kamran Bagheri Lankarani, Ali Reza Taghavi, Fardad Ejtehadi
BACKGROUND: The natural history of ulcerative colitis (UC) after liver transplantation (LT) for primary sclerosing cholangitis (PSC) remains ill defined. This study aimed to evaluate the course of UC after LT for PSC. METHODS: The course of UC, including the clinical colitis severity index, was evaluated in patients with concomitant PSC and UC who received LT for PSC-induced end-stage liver disease. A total of 167 (55.4%) patients with PSC had concurrent inflammatory bowel disease (IBD)...
May 16, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28520499/genome-wide-identification-of-potential-drug-target-in-enterobacteriaceae-family-a-homology-based-method
#6
Morteza Hadizadeh, Seyyede Nasim Tabatabaiepour, Seyyede Zahra Tabatabaiepour, Hossein Hosseini Nave, Mohsen Mohammadi, Seyyed Mohsen Sohrabi
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore forming rod-shaped bacteria that includes harmless and pathogenic organisms. The emergence and development of drug resistance in Enterobacteriaceae is complicating the treatment of serious infections. The aim of this study is to predict and characterize putative drug targets in Enterobacteriaceae family employing a homology-based computational method. The final putative drug targets were qualitatively characterized via cellular function prediction, subcellular localization prediction, broad-spectrum, and druggability analyses...
May 18, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28513230/association-of-renin-angiotensin-aldosterone-system-gene-polymorphisms-with-left-ventricular-hypertrophy-in-patients-with-heart-failure-with-preserved-ejection-fraction-a-case-control-study
#7
Ehsan Bahramali, Negar Firouzabadi, Mona Rajabi, Alireza Manafi, Mehrdad Zarghami, Seyyed Mohammad Mousavi, Javad Jamshidi
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has close ties with hypertension, though risk factors to the development of HFpEF in hypertensive patients are not fully understood. Left ventricular hypertrophy (LVH) signifies the susceptibility toward diastolic heart dysfunction, and genetic determinants of LVH as a result may serve as risk predictors for HFpEF in hypertension. We investigated the role of three renin-angiotensin-aldosterone system (RAAS) gene polymorphisms in the development of LVH in hypertensive patients with a diagnosis of HFpEF...
May 17, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28512489/effect-of-deep-cryogenic-treatment-on-cyclic-fatigue-of-endodontic-rotary-nickel-titanium-instruments
#8
Mohammad Yazdizadeh, Masoumeh Skini, Seyyed Mohsen Hoseini Goosheh, Mansour Jafarzadeh, Milad Shamohammadi, Vahid Rakhshan
INTRODUCTION: Cyclic fatigue is the common reason for breakage of rotary instruments. This study was conducted to evaluate the effect of cryogenic treatment (CT) in improving the resistance to cyclic fatigue of endodontic rotary instruments. METHODS AND MATERIALS: In this in vitro study, 20 RaCe and 20 Mtwo files were randomly divided into two groups of negative control and CT. CT files were stored in liquid nitrogen at -196(°)C for 24 h, and then were gradually warmed to the room temperature...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28508842/a3-adenosine-receptor-agonist-induce-g1-cell-cycle-arrest-via-cyclin-d-and-cyclin-dependent-kinase-4-pathways-in-ovcar-3-and-caov-4-cell-lines
#9
Hamid Reza Joshaghani, Seyyed Mehdi Jafari, Mahmoud Aghaei, Mojtaba Panjehpour, Hamideh Abedi
AIM OF THE STUDY: The cell cycle, a vital process that involves in cells' growth and division, lies at the heart of cancer. It has been shown that IB-MECA, an A3 adenosine receptor agonist inhibits the proliferation of cancer cells by inducing cell cycle arrest in several tumors. In this study, we evaluated the role of IB-MECA inhibition in cell cycle progression in ovarian cancer cells. MATERIALS AND METHODS: Cell viability was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay in Caov-4 and OVCAR-3...
January 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28488393/in-vitro-analysis-of-early-calcification-in-aortic-valvular-interstitial-cells-using-laser-induced-breakdown-spectroscopy-libs
#10
Seyyed Ali Davari, Shirin Masjedi, Zannatul Ferdous, Dibyendu Mukherjee
Calcific aortic valve disease (CAVD) is a major cardiovascular disorder caused by osteogenic differentiation of valvular interstitial cells (VICs) within aortic valves. Conventional methods like colorimetric assays and histology fail to detect small calcium depositions during in-vitro VIC cultures. Laser-induced breakdown spectroscopy (LIBS) is a robust analytical tool used for inorganic materials characterizations, but relatively new to biomedical applications. We employ LIBS, for the first time, for quantitative in-vitro detection of calcium depositions in VICs at various osteogenic differentiation stages...
May 9, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28481047/enhanced-chondrogenic-differentiation-of-stem-cells-using-an-optimized-electrospun-nanofibrous-plla-peg-scaffolds-loaded-with-glucosamine
#11
Samaneh Mirzaei, Akbar Karkhaneh, Masoud Soleimani, Abdolreza Ardeshirylajimi, Hasti Seyyed Zonouzi, Hana Hanaee-Ahvaz
Recently, tissue engineering has become one of the most important approaches in medical research for the treatment of injuries and lesions. In the present study, Poly (L-lactide) acid (PLLA), and Poly ethylene glycol (PEG) with different ratios and PEG molecular weights were used in order to produce appropriate nanofibrous scaffolds using the electrospinning technique for cartilage tissue engineering applications. Glucosamine was also incorporated into the polymeric scaffolds to enhance the biological properties...
May 8, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28479970/assessment-of-salient-beliefs-affecting-mothers-intention-to-adherence-to-dietary-diversity-in-their-children-s-complementary-feeding
#12
Akram Karimi-Shahanjarini, Fatemeh Rahmani, Ghodratollah Roshanei, Seyyed M Mahdi Hazavehei
BACKGROUND: Providing a variety of foods has been emphasized as one of the most important features of optimal complementary feeding. This study investigated key beliefs that guide mothers' intention to adherence to dietary diversity in their 1-2-year-old children's complementary feeding. METHODS: This was a cross-sectional study involving 290 mothers (mean age = 27, standard deviation = 5.32) with child 1-2-year-old attending maternal and child health section of health centers in Rasht, Iran...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28479962/effect-of-health-care-as-the-home-visiting-on-postpartum-depression-a-controlled-clinical-trial
#13
Hourieh Shamshiri Milani, Parastoo Amiri, Maryam Mohsey, Esmat Davoudi Monfared, Seyyed Mohammadreza Vaziri, Akram Malekkhahi, Fatemeh Salmani
BACKGROUND: Postpartum depression is considered as a major health complication of women after delivery. It is necessary to find an essential approach for the prevention of its serious consequences on mothers' and infants' health. The aim of this study was to investigate the effect of home visiting on postpartum depression. METHODS: The first stage of study was the design of postpartum package. According to the package, a clinical trial was performed for 276 mothers who had delivered in affiliated hospitals of Shahid Beheshti University in 2013 and were divided into two groups, i...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28479912/locally-manufactured-wheelchairs-in-tanzania-are-users-satisfied
#14
Seyi Amosun, Aston Ndosi, Helen Buchanan
BACKGROUND: The government of Tanzania created opportunity for the production of wheelchairs that would be appropriate to the local needs and environment. OBJECTIVES: The study assessed the extent to which the wheelchairs met the activity and participation needs of the users, as well as the users' level of satisfaction with the provision, repair and maintenance of these wheelchairs. METHODS: A descriptive cross-sectional analytical design was utilized to collect data through the administration of a questionnaire among 75 adult wheelchair users...
December 2016: African Health Sciences
https://www.readbyqxmd.com/read/28470318/mechanochemical-synthesis-of-nanostructured-metal-nitrides-carbonitrides-and-carbon-nitride-a-combined-theoretical-and-experimental-study
#15
Seyyed Amin Rounaghi, Danny E P Vanpoucke, Hossein Eshghi, Sergio Scudino, Elaheh Esmaeili, Steffen Oswald, Jürgen Eckert
Nowadays, the development of highly efficient routes for the low cost synthesis of nitrides is greatly growing. Mechanochemical synthesis is one of those promising techniques which is conventionally employed for the synthesis of nitrides by long term milling of metallic elements under a pressurized N2 or NH3 atmosphere (A. Calka and J. I. Nikolov, Nanostruct. Mater., 1995, 6, 409-412). In the present study, we describe a versatile, room-temperature and low-cost mechanochemical process for the synthesis of nanostructured metal nitrides (MNs), carbonitrides (MCNs) and carbon nitride (CNx)...
May 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28469045/effect-of-educational-program-based-on-precede-and-trans-theoretical-models-on-preventing-decline-in-regular-physical-activity-and-improving-it-among-students
#16
Masomeh Rostami-Moez, Forouzan Rezapur-Shahkolai, Seyyed Mohammad-Mahdi Hazavehei, Manoochehr Karami, Akram Karimi-Shahanjarini, Farzad Nazem
BACKGROUND: Adolescents especially middle school girls do not follow 60 min of regular physical activity (RPA), recommended by WHO, and endure physical activity decline. Using theory-based interventional program, considering the age of decline in RPA, seems to be effective. The aim of this study was to determine the effects of educational program, based on PRECEDE and Trans-Theoretical models, on preventing decline in RPA and improving it among 7th grade girl students. STUDY DESIGN: Randomized controlled trial...
April 10, 2017: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/28465803/the-prevalence-and-expression-pattern-of-melanoma-associated-antigen-1-in-esophageal-squamous-cell-carcinoma-a-historical-cohort-study
#17
Kazem Anvari, Azar Fani Pakdel, Bahram Memar, Roya Parsamanesh, Seyyed Mojtaba Ejlalzadeh, Seyed Alireza Javadinia
INTRODUCTION: Melanoma-associated antigen 1 (MAGE1) expression in normal tissues is restricted to the testes, whilst being over-expressed in a number of human cancers. This feature of MAGE1 makes it a promising cancer biomarker. This study aimed to determine the expression of MAGE1 in esophageal squamous cell carcinoma (SCC) and its relationship with clinicopathological factors. METHODS: This is a cross-sectional study conducted on pretreatment endoscopic tissue specimens of 43 patients with non-metastatic esophageal SCC, admitted to Omid Hospital, Mashhad, Iran, between 2011 and 2013...
February 2017: Electronic Physician
https://www.readbyqxmd.com/read/28459663/does-evolocumab-as-a-pcsk9-inhibitor-ameliorate-the-lipid-profile-in-familial-hypercholesterolemia-patients-a-meta-analysis-of-randomized-controlled-trials
#18
Seyyed Majid Eslami, Shekoufeh Nikfar, Maryam Ghasemi, Mohammad Abdollahi
Proprotein convertase subtilisin-kexin type 9 (PCSK9) is a member of regulatory serine proteases which is mostly expressed in liver. In the physiological condition, LDL-C binds to LDL receptors (LDLRs) and via endocytosis, LDLRs are degraded. PCSK9 binds to the epidermal growth factor-like repeat A (EGFA) domain of extracellular LDLRs, and then physiological recycling of LDLRs from surface of liver is cancelled, resulting in elevation of circulating LDL-C in plasma. To evaluate whether evolucomab, as PCSK9 inhibitor monoclonal antibody, ameliorates lipid profile in familial hypercholesterolemia (FH) patients, this meta-analysis has been conducted...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28451535/simultaneous-molecular-detection-of-salmonella-enterica-serovars-typhi-enteritidis-infantis-and-typhimurium
#19
Reza Ranjbar, Seyyed Mojtaba Mortazavi, Ali Mehrabi Tavana, Meysam Sarshar, Ali Najafi, Rahim Soruri Zanjani
BACKGROUND: Salmonella enterica serovar Typhi, as causative agent of typhoid fever, is one of the most important endemic pathogens. Non-typhoidal Salmonella serovars, including Typhimurium, Infantis, and Enteritidis are amongst the most prevalent serotypes worldwide and in developing areas such as Iran. The aim of this study was to apply a uniplex PCR for rapid detection of Salmonella spp., and a multiplex PCR for the simultaneous detection of the four most common Salmonella serovars in Iran...
January 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28433995/effect-of-prophylactic-dialysis-on-morbidity-and-mortality-in-non-dialysis-dependent-patients-after-coronary-artery-bypass-grafting-a-pilot-study
#20
Roghayeh Borji, Seyyed Hossein Ahmadi, Khosrow Barkhordari, Ali Pasha Meysami, Abbas Ali Karimi, Seyedeh Hamideh Mortazavi, Parinaaz Dadlani, Farah Ayatollah Zadeh Esfahani, Seyyed Mohammad Reza Khatami
BACKGROUND/AIMS: Coronary artery bypass grafting (CABG) is associated with an increased risk of morbidity and mortality in patients with pre-existing renal dysfunction. Numerous measures have been implemented to overcome this problem; however, no improvement in outcomes has been achieved. This study was aimed at investigating the effects of prophylactic dialysis on mortality and morbidity in these patients. METHODS: This randomized-controlled clinical trial enrolled 88 non-dialysis-dependent patients with chronic kidney disease awaiting CABG surgery...
April 22, 2017: Nephron
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