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https://www.readbyqxmd.com/read/28944412/a-head-to-head-comparison-of-4-l-polyethylene-glycol-and-low-volume-solutions-before-colonoscopy-which-is-the-best-a-multicentre-randomized-trial
#1
Vladimir Kojecky, Jan Matous, Radan Keil, Milan Dastych, Radek Kroupa, Zdena Zadorova, Michal Varga, Jiri Dolina, Milan Kment, Ales Hep
PURPOSE: The purpose of this study is to compare the efficacy and tolerability of polyethylene glycol (PEG) to sodium picosulfate/magnesium citrate (SPMC) and low-volume polyethylene glycol/ascorbic acid (PEGA) in a single- or split-dose regimen for colonoscopy bowel preparation. METHODS: This was a prospective, randomized, endoscopist-blinded, multicentre study. Outpatients received either PEG or SPMC or PEGA in a single or a split dose before the colonoscopy. Quality and tolerability of the preparation and complaints during preparation were recorded...
September 24, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28939500/impact-of-patient-audio-visual-re-education-through-a-smartphone-on-quality-of-bowel-preparation-before-colonoscopy-a-single-blinded-randomized-study
#2
Su Young Back, Hyun Gun Kim, Eu Mi Ahn, Suyeon Park, Seong Ran Jeon, Hee Hyuk Im, Jin-Oh Kim, Bong Min Ko, Joon Seong Lee, Tae Hee Lee, Jun-Hyung Cho
BACKGROUND AND AIMS: Preparation education is essential for successful colonoscopy. This study aimed to evaluate the impact of audio-visual (AV) re-education through a smartphone before colonoscopy on bowel preparation quality. METHODS: A prospective, endoscopist-blinded, randomized, controlled study was performed. Patients who underwent colonoscopy with 3 purgatives, including 4 L polyethylene glycol (4L-PEG), 2 L PEG with ascorbic acid (2L-PEG/Asc) and sodium picosulfate with magnesium citrate (SPMC), were enrolled, and randomized into AV re-education through smartphone group (AV group, n=160) and a control group (n=160)...
September 19, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28932091/randomized-clinical-trial-comparing-fixed-time-split-dosing-and-split-dosing-of-oral-picosulfate-regimen-for-bowel-preparation
#3
Jae Hyuck Jun, Koon Hee Han, Jong Kyu Park, Hyun Il Seo, Young Don Kim, Sang Jin Lee, Baek Gyu Jun, Min Sik Hwang, Yoon Kyoo Park, Myeong Jong Kim, Gab Jin Cheon
AIM: To compare the efficacy of fixed-time split dose and split dose of an oral sodium picosulfate for bowel preparation. METHODS: This is study was prospective, randomized controlled study performed at a single Institution (2013-058). A total of 204 subjects were assigned to receive one of two sodium picosulfate regimens (i.e., fixed-time split or split) prior to colonoscopy. Main outcome measurements were bowel preparation quality and subject tolerability. RESULTS: There was no statistical difference between the fixed-time split dose regimen group and the split dose regimen group (Ottawa score mean 2...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28894587/comparison-of-claims-data-on-hospitalization-rates-and-repeat-procedures-in-patients-receiving-a-bowel-preparation-prior-to-colonoscopy
#4
Lisa E Young, Naomi C Sacks, Philip L Cyr, Abhishek Sharma, David N Dahdal
OBJECTIVES: To evaluate outcomes of colorectal screening using sodium picosulfate and magnesium citrate compared with other prescription bowel-preparation agents. Primary endpoints were rates of procedure-associated hospitalizations, diagnosis at hospitalization, and rates of early repeat screenings. METHODS: This retrospective cohort study identified patients using the Truven Health Analytics MarketScan databases, which contain fully adjudicated, de-identified, medical- and prescription-drug claims, as well as demographic and enrollment information for individuals with commercial, Medicaid, and Medicare supplemental insurance coverage...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/28830134/split-dose-bowel-preparation-for-colonoscopy-2-liters-polyethylene-glycol-with-ascorbic-acid-versus-sodium-picosulfate-versus-oral-sodium-phosphate-tablets
#5
Seok Won Lee, Chang Seok Bang, Tae Young Park, Ki Tae Suk, Gwang Ho Baik, Dong Joon Kim
Background/Aims: Adequate bowel preparation is an essential factor affecting the visibility of colonic mucosa and safety of related therapeutic interventions. The aim of this study was to assess the efficacy, tolerability, and safety of three bowel preparation agents -2 L polyethylene glycol with ascorbic acid (PEGA), sodium picosulfate magnesium citrate (SPMC), and oral sodium phosphate tablet (NaP)- for morning colonoscopy. Methods: Here, we analyzed the medical records of patients who had taken bowel preparation agents using the split-dose method and undergone colonoscopy in a single hospital...
August 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28673219/the-effect-of-oral-intake-during-the-immediate-pre-colonoscopy-time-period-on-volume-depletion-in-patients-who-receive-sodium-picosulfate
#6
G S Labuschagne, R W Morris
Sodium picosulfate, used in combination with magnesium oxide and citric acid for bowel cleansing, can result in dehydration. We investigated whether enhanced carbohydrate fluid intake pre-colonoscopy could mitigate this effect. We enrolled 398 elective colonoscopy patients in a prospective, controlled, single-blinded study. The control group (n=194) fasted routinely (minimum seven hours) whilst the treatment group (n=197) drank 1,200 ml carbohydrate solution leading up to admission (up until two hours pre-colonoscopy)...
July 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28660084/a-case-of-thermal-esophageal-injury-induced-by-sodium-picosulfate-with-magnesium-citrate
#7
Dong-Hyuk Yang, Byoung Wook Bang, Kye Sook Kwon, Hyung Kil Kim, Yong Woon Shin
Although thermal esophageal injuries caused by hot food or tea have been reported, thermal esophageal injury due to sodium picosulfate with magnesium citrate (PSMC) used for bowel preparation is rarely reported. We report the case of a 56-year-old man who presented with esophageal injury after ingestion of PSMC. Instead of dissolving the PSMC in water before ingestion, he drank water immediately after swallowing PSMC powder. As soon as he drank water, he developed severe chest pain and hematemesis. Upper endoscopy revealed severe hemorrhagic, ulcerative mucosal change from upper to mid-esophagus...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28573174/optimal-intake-of-clear-liquids-during-preparation-for-afternoon-colonoscopy-with-low-volume-polyethylene-glycol-plus-ascorbic-acid
#8
Masahiro Tajika, Tsutomu Tanaka, Makoto Ishihara, Yutaka Hirayama, Sachiyo Oonishi, Nobumasa Mizuno, Kazuo Hara, Susumu Hijioka, Hiroshi Imaoka, Toshihisa Fujiyoshi, Nobuhiro Hieda, Nozomi Okuno, Tsukasa Yoshida, Kenji Yamao, Vikram Bhatia, Masahiko Ando, Yasumasa Niwa
BACKGROUND AND STUDY AIMS : The standard colonoscopy preparation regimen in Japan for afternoon procedures is sequential intake of 1 L of polyethylene glycol electrolyte lavage solution containing ascorbic acid (PEG-ASC), 0.5 L of clear liquid, 0.5 L of PEG-ASC, and finally 0.25 L of clear fluids (all at a rate of 0.25 L every 15 min). However, this regimen seems poorly tolerated and complicated for many patients compared to previous regimen of polyethylene glycol electrolyte lavage solution...
June 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28246889/an-evaluation-of-the-prevalence-of-potentially-inappropriate-medications-in-older-people-with-cognitive-impairment-living-in-northern-sweden-using-the-eu-7-pim-list
#9
Eva Sönnerstam, Maria Sjölander, Maria Gustafsson
PURPOSE: As people get older, their sensitivity to drugs and adverse drug reactions can increase due to pharmacokinetic and pharmacodynamic changes. Older people with dementia are a particularly vulnerable group of people. They are at an increased risk of being prescribed potentially inappropriate medications, which may lead to harmful consequences. The aim of this study was to investigate the prevalence of potentially inappropriate medications among older patients with cognitive impairment...
June 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28062864/-comparison-of-colon-cleansing-methods-in-preparation-for-colonoscopy-comparative-of-solutions-of-mannitol-and-sodium-picosulfate
#10
COMPARATIVE STUDY
Diogo Turiani de Moura, Hugo Guedes, Verônica Tortoretto, Tayrê Pádua Arataque, Eduardo Guimarães de Moura, Juan Pablo Román, Gustavo Luis Rodela, Everson L Artifon
OBJECTIVES: The purpose of the present study is to compare intestinal preparation with mannitol and sodium picosulphate, assessing patient's acceptance, side effects and cleaning capacity. MATERIAL AND METHODS: This is a prospective, nom randomized, blind study, in which the evaluator had no information about the preparation applied. The sample obtained was divided into two groups according to the bowel preparation applied, with 153 patients prepared with 10% mannitol and 84 patients with sodium picosulfate...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28055031/a-customized-mobile-application-in-colonoscopy-preparation-a-randomized-controlled-trial
#11
Ala I Sharara, Jean M Chalhoub, Maya Beydoun, Rani H Shayto, Hamed Chehab, Ali H Harb, Fadi H Mourad, Fayez S Sarkis
OBJECTIVES: Adherence with diet and prescribed purgative is essential for proper cleansing with low-volume bowel preparations. The aim of this work was to assess the effect of a customized mobile application (App) on adherence and quality of bowel preparation. METHODS: One hundred and sixty (160) eligible patients scheduled for elective colonoscopy were randomly assigned to paper (control) or App-based instructions. The preparation consisted of low-fiber diet for 2 days, clear fluids for one day and split-dose sodium picosulfate/magnesium citrate (SPS)...
January 5, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27859712/feasibility-and-safety-of-bowel-cleansing-using-low-volume-polyethylene-glycol-with-ascorbic-acid-before-pediatric-colonoscopy-a-pilot-study
#12
Tomoyuki Tsunoda, Tsuyoshi Sogo, Kentaro Iwasawa, Shuichiro Umetsu, Manari Oikawa-Kawamoto, Ayano Inui, Tomoo Fujisawa
BACKGROUND AND AIM: To assess the feasibility and safety of same-day regimen of low-volume polyethylene glycol solution with ascorbic acid for bowel cleansing before colonoscopy in children. METHODS: Data on children who received polyethylene glycol solution with ascorbic acid for bowel cleansing in our department were retrospectively analyzed. On the day before the procedure, patients ate a low-residue diet and received sodium picosulfate in the evening. The following day, patients took polyethylene glycol solution with ascorbic acid in the morning; the procedure was carried out in the afternoon...
October 19, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27844063/influence-of-atomic-bonds-on-the-properties-of-the-laxative-drug-sodium-picosulphate
#13
Davide Romani, Isabel Salas Tonello, Silvia Antonia Brandán
In this work, the influence of the different S═O, S-O, N⋯H, O⋯H, Na⋯O bonds present in the structures of the powerful laxative drug, sodium picosulphate in gas and aqueous solution phases were studied combining the density functional theory (DFT) calculations with the experimental available infrared, (1)H NMR and UV-visible spectra. The structural, topological, electronic and vibrational properties were investigated in both media by using the hybrid B3LYP/6-31G* method and the integral equation formalism variant polarised continuum model (IEFPCM)...
November 2016: Heliyon
https://www.readbyqxmd.com/read/27752627/upper-airway-obstruction-resulting-from-acute-mucosal-injury-induced-by-direct-ingestion-of-sodium-picosulfate-magnesium-citrate-powder
#14
Gyeong Bo Kim, Sung Yeon Hwang, Tae Gun Shin, Tae Rim Lee, Won Chul Cha, Min Seob Sim, Ik Joon Jo, Keun Jeong Song, Joong Eui Rhee, Yeon Kwon Jeong
A 59-year-old man presented to the emergency department with a chief complaint of sore throat after swallowing sodium picosulfate/magnesium citrate powder for bowel preparation, without first dissolving it in water. The initial evaluation showed significant mucosal injury involving the oral cavity, pharynx, and epiglottis. Endotracheal intubation was performed for airway protection in the emergency department, because the mucosal swelling resulted in upper airway compromise. After conservative treatment in the intensive care unit, he underwent tracheostomy because stenosis of the supraglottic and subglottic areas was not relieved...
June 2016: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/27750301/review-prucalopride-velusetrag-bisacodyl-and-sodium-picosulfate-improve-chronic-idiopathic-constipation
#15
Judy Nee, Joseph D Feuerstein
No abstract text is available yet for this article.
October 18, 2016: Annals of Internal Medicine
https://www.readbyqxmd.com/read/27732774/acute-gastric-injury-caused-by-undissolved-sodium-picosulfate-magnesium-citrate-powder
#16
Eun Young Ze, Chang Hwan Choi, Jeong Wook Kim
Sodium picosulfate/magnesium citrate (SPMC) is a widely used oral bowel cleansing agent considered to be relatively safe. However, partially dissolved or undissolved SPMC powder may cause severe injuries of the esophagus and stomach. We report a very rare case of acute gastric injury without esophageal damage caused by the ingestion of undissolved SPMC powder. A 69-year-old man experienced epigastric pain after swallowing SPMC powder without dissolving it in water in preparation for a screening colonoscopy...
January 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/27689192/superiority-of-a-split-dose-regimen-of-sodium-picosulfate-magnesium-citrate-spmc-in-comparison-to-a-prior-day-schedule-am-pm-for-colonoscopy-preparation-a-randomized-single-blinded-study
#17
RANDOMIZED CONTROLLED TRIAL
Christian Schulz, Joachim Müller, Joachim Sauter, Stephan Miehlke, Christoph Schmöcker, Dirk Hartmann, Peter Malfertheiner, Carlos Badiola
BACKGROUND AND AIMS: Split-dose regimens are generally recommended for bowel cleansers. However, other regimens still remain in the summary of product characteristics of some bowel cleansers in Europe. The aim of this study is to compare the efficacy and safety of a split-dose regimen of sodium picosulfate/magnesium citrate (SPMC) with a prior-day schedule (AM/PM). METHODS: Multicenter, randomized (EudraCT no. 2013-001620-20), endoscopist-blinded, parallel study, carried out in subjects 18 years or older undergoing elective colonoscopy...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27606043/sensory-characterization-of-bowel-cleansing-solutions
#18
Ala I Sharara, Hamza Daroub, Camille Georges, Rani Shayto, Ralph Nader, Jean Chalhoub, Ammar Olabi
AIM: To evaluate the sensory characteristics of commercial bowel cleansing preparations. METHODS: Samples of 4 commercially available bowel cleansing preparations, namely polyethylene glycol electrolyte solution (PEG), PEG + ascorbic acid (PEG-Asc), sodium picosulfate (SPS), and oral sodium sulfate (OSS) were prepared according to the manufacturer's instructions. Descriptive analysis was conducted (n = 14) using a 15-cm line scale with the Compusense at-hand(®) sensory evaluation software...
August 10, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27559255/specialist-pediatric-palliative-care-prescribing-practices-a-large-5-year-retrospective-audit
#19
Anuja Damani, Naveen Salins, Arunangshu Ghoshal, MaryAnn Muckaden
INTRODUCTION: There is a gradual increasing trend in childhood cancers in India and pediatric palliative care in India is an emerging specialty. Prescribing pain and symptom control drugs in children with cancer requires knowledge of palliative care formulary, dosing schedules, and prescription guidelines. This study is a retrospective audit of prescribing practices of a specialist palliative care service situated in a tertiary cancer center. METHODS: A total of 1135 medication records of children receiving specialist pediatric palliative care services were audited for 5 years (2010-2014) to evaluate prescribing practices in children with advanced cancer...
July 2016: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/27487795/safety-and-efficacy-of-a-same-day-low-volume-1%C3%A2-l-peg-bowel-preparation-in-colonoscopy-for-the-elderly-people-and-people-with-renal-dysfunction
#20
Naohisa Yoshida, Yuji Naito, Takaaki Murakami, Ryohei Hirose, Kiyoshi Ogiso, Yutaka Inada, Osamu Dohi, Tetsuya Okayama, Kazuhiro Kamada, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu Handa, Hideyuki Konishi, Kewin Tien Ho Siah, Nobuaki Yagi, Yoshito Itoh
INTRODUCTION: A same-day low-volume 1 L polyethylene glycol (PEG) for bowel preparation before colonoscopy was developed to improve patients' compliance. We aimed to evaluate the efficacy and safety of this regimen especially for the elderly and patients with renal dysfunction. METHODS: All consecutive patients who underwent colonoscopy in our center from November 2014 to September 2015 were included. Patients undertook a low-residue diet with 10 mL sodium picosulfate 1 day before colonoscopy...
November 2016: Digestive Diseases and Sciences
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