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case study in neurology

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https://www.readbyqxmd.com/read/29913031/four-year-survival-of-a-patient-with-spinal-metastatic-acinic-cell-carcinoma-after-a-total-en-bloc-spondylectomy-and-reconstruction-with-a-frozen-tumor-bearing-bone-graft
#1
Apiruk Sangsin, Hideki Murakami, Takaki Shimizu, Satoshi Kato, Hiroyuki Tsuchiya
Acinic cell carcinoma metastasizing to the spine is extremely rare. The authors present a case of acinic cell carcinoma of the parotid gland with subsequent lung and spinal metastases, treated with en bloc spondylectomy. A 41-year-old man presented with a left parotid mass. After being diagnosed with acinic cell carcinoma, he underwent a total parotidectomy. Imaging studies revealed a metastatic osteoblastic lesion in the T4 vertebral body and multiple lung metastases. Total en bloc spondylectomy and reconstruction with a frozen tumor-bearing bone graft were performed to treat the T4 metastasis...
June 18, 2018: Orthopedics
https://www.readbyqxmd.com/read/29912724/selection-of-patients-recumbent-position-laterality-according-to-physician-handedness-bias-increases-the-success-rate-of-lumbar-puncture-a-multicenter-study
#2
Jian-Lan Zhao, Yi-Rui Sun, Qiao Shan, Zhi-Peng Xiao, Ben-Chao Hou, Jin Hu
BACKGROUND: Lumbar puncture (LP) is a medical procedure required during spinal anesthesia and for obtaining cerebrospinal fluid samples in the diagnosis of neurological disorders. The aim of this study was to assess the effects of physicians' handedness bias and the laterality of patients' recumbent position on the success rate of LPs. METHODS AND PATIENTS: A prospective multicenter study including 36 physicians (18 left-handed and 18 right-handed) and 7200 patients was conducted in 6 medical centers...
June 15, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29912656/neurological-impairments-in-hypoxic-neonates-and-lactate-levels
#3
Miljana Z Jovandaric, Svetlana J Milenkovic
INTRODUCTION: Metabolic acidosis with increasing lactate concentration develops due to the lack of oxygen in the tissues. OBJECTIVES: The effect of lactic acidosis on neurological development in the first year of life. MATERIALS AND METHODS: Our study included 50 newborns with perinatal hypoxia requiring oxygen therapy and 50 healthy newborns. pH, pCO2, pO2, base excess (BE) and lactates from arterialized capillary blood were determined in both groups of newborns, in the first and second hours after birth, and neurological development in the first year of life was estimated...
June 18, 2018: Neurological Research
https://www.readbyqxmd.com/read/29912303/early-juvenile-htlv-1-associated-myelopathy-tropical-spastic-paraparesis-ham-tsp-study-of-25-patients
#4
Cinthya Maria Neves Varandas, José Lucas Sena da Silva, Janeusa Rita L Primo, Maria de Fátima S P de Oliveira, Otávio Moreno-Carvalho, Lourdes Farre, Achiléa L Bittencourt
Background: HTLV-1 may cause severe diseases such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated to HTLV-1 (IDH). The clinical characteristics and progression of 25 early onset HAM/TSP associated or not to IDH were described. Methods: Following-up 37 IDH patients with neurological examinations, 54% developed HAM/TSP. To these cases were added five cases of juvenile HAM/TSP. The patients were HTLV-1+ and were submitted to dermatological and neurological examinations...
April 18, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29912032/spinopelvic-dissociation-a-retrospective-case-study-and-review-of-treatment-controversies
#5
Daud Tai Shan Chou, Ibraheim El-Daly, Arun Ranganathan, Alexander Montgomery, Paul Culpan, Peter Bates
INTRODUCTION: Spinopelvic dissociation is a rare injury resulting in discontinuity between the spine and pelvis. We review the English- language literature and discuss critical treatment controversies. We present a series of spinopelvic dissociation cases from a level I trauma center. METHODS: In this retrospective review of 18 consecutive cases treated surgically over a period of 4 years, we collected patient, injury, and surgical demographics and clinical and radiographic outcome measures...
June 14, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29911601/oral-oxycodone-for-pain-after-caesarean-section-a-randomized-comparison-with-nurse-administered-iv-morphine-in-a-pragmatic-study
#6
Boel Niklasson, Catarina Arnelo, Susanne Georgsson Öhman, Märta Segerdahl, Agneta Blanck
Background and aims The present randomized open label parallel group study was conducted to evaluate if an oral oxycodone (OXY) regimen can be at least equally effective and as safe for postoperative analgesia after caesarean section (CS) as a standard of care program using nurse-administered intravenous morphine (IVM), followed by oral codeine. Methods Eighty women (40 + 40) were scheduled for elective CS under spinal anaesthesia. All patients received postoperative multimodal analgesic therapy, including ibuprofen and paracetamol...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911023/cavernous-sinus-syndrome-in-dogs-and-cats-case-series-2002-2015
#7
Aslynn M Jones, Ellison Bentley, Helena Rylander
The cavernous sinus (CS) is a paired venous sinus that runs along either side of the pituitary gland on the floor of the calvarium. Cavernous sinus syndrome (CSS) refers to deficits in more than one of the cranial nerves III, IV, V, and VI, as they are in close association in this region. The purpose of this study was to identify the presenting complaints, neurologic findings, diagnosis, and outcomes in dogs and cats with confirmed cavernous sinus syndrome (CSS). Medical records between 2002 and 2015 were reviewed...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29910637/combined-microwave-ablation-and-minimally-invasive-open-decompression-for-the-management-of-thoracic-metastasis-in-breast-cancer
#8
Bin Liu, Zhenchao Yuan, Chang Yuan Wei
Objective: The incidence rate of thoracic metastasis from breast cancer is increasing. Microwave ablation is one type of clinical therapy used to treat metastatic spine disease, although it can cause protein denaturation and immediate cell death, and coagulative necrosis can occur. Minimally invasive open decompression is associated with lower rates of surgical complications in comparison to traditional open surgery. Therefore, it is an alternative therapeutic option for spinal metastases...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29909695/anti-infective-treatment-of-brain-abscess
#9
Jacob Bodilsen, Matthijs C Brouwer, Henrik Nielsen, Diederik van de Beek
INTRODUCTION: Brain abscess is an uncommon and potentially life-threatening infection of the CNS that can be caused by a range of different pathogens including bacteria, fungi and parasites. A multidisciplinary approach is important and anti-infective treatment remains crucial. Here, we review anti-infective treatment of brain abscess. Areas covered: We used the terms '(Brain abscess[ti] AND (antibiotic* OR treatment)) NOT case report'), to conduct a search in the PubMed. Additional papers were identified by cross-reference checking and by browsing textbooks of infectious diseases and neurology...
June 18, 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29909560/rhinencephalon-changes-in-tuberous-sclerosis-complex
#10
Renzo Manara, Davide Brotto, Samuela Bugin, Maria Federica Pelizza, Stefano Sartori, Margherita Nosadini, Sara Azzolini, Giorgio Iaconetta, Cecilia Parazzini, Alessandra Murgia, Angela Peron, Paola Canevini, Francesca Labriola, Aglaia Vignoli, Irene Toldo
PURPOSE: Despite complex olfactory bulb embryogenesis, its development abnormalities in tuberous sclerosis complex (TSC) have been poorly investigated. METHODS: Brain MRIs of 110 TSC patients (mean age 11.5 years; age range 0.5-38 years; 52 female; 26 TSC1, 68 TSC2, 8 without mutation identified in TSC1 or TSC2, 8 not tested) were retrospectively evaluated. Signal and morphological abnormalities consistent with olfactory bulb hypo/aplasia or with olfactory bulb hamartomas were recorded...
June 17, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29909214/classification-and-protection-of-peritumoral-draining-veins-of-parasagittal-and-falcine-meningiomas
#11
Xuan Wang, Meng-Yang Wang, Kang Qian, Long Chen, Fang-Cheng Zhang
OBJECTIVE: This study aims to investigate the importance and types of peritumoral draining veins in parasagittal and falcine meningiomas, and administer corresponding protective strategies during surgery according to these different types, in order to improve tumor resection rate and maximize the protection of neurological functions. METHODS: The clinical information of 156 patients with parasagittal and falcine meningiomas, who were admitted at the Neurosurgery Department of our hospital, was collected and retrospectively analyzed...
June 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29908718/effects-of-cognitive-and-motor-rehabilitation-in-non-convulsive-status-epilepticus-a-case-report
#12
Francesco Corallo, Viviana Lo Buono, Marcella Di Cara, Simona De Salvo, Giuliana Vermiglio, Patrizia Pollicino, Placido Bramanti, Silvia Marino, Carmela Rifici
Epilepsy is a neurological disorder characterized by recurrent and unpredictable interruptions of normal brain function, that implies neurobiologic, psychological, and social consequences. Non-convulsive status epilepticus (NCSE) is an electro-clinical state associated to altered level of consciousness. In NCSE could occur the behavioural and emotional disorder, cognitive impairment and psychiatric disorder with a negative impact on quality of life and adaptive social behaviours. Cognitive rehabilitation for epileptic patients may include internal compensation strategies, external memory aids, psychoeducation, verbal and visual memory training, attention exercise and executive functions...
June 13, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29908380/the-impact-of-extubation-failure-in-patients-with-good-grade-subarachnoid-hemorrhage
#13
Jann F Wojak, Claudia Ditz, Abdulkareem Abusamha, Emma Smith, Jan Gliemroth, Volker Tronnier, Jan Küchler
OBJECTIVE: The aim of this study was to analyze the clinical impact of extubation failure (EF) in with good grade subarachnoid hemorrhage (SAH), in which a good clinical course is usually expected. PATIENTS AND METHODS: We reviewed the clinical data from 141 patients with SAH and i. initial Hunt & Hess grade 1-3 ii. induction of general anesthesia for intervention and iii. the presence of data about the functional outcome. Patients were divided into three groups: 1...
June 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29907475/radiotherapy-for-langerhans-cell-histiocytosis-with-paraplegia-a-rare-oncologic-emergency-case-report-in-infancy-and-literature-review
#14
Kentaro Nakashima, Yuhki Koga, Yasunari Sakai, Hidetoshi Takada, Katsumi Harimaya, Saiji Ohga, Tomoaki Taguchi, Yoshinao Oda, Hiroshi Honda, Shouichi Ohga
BACKGROUND: Langerhans cell histiocytosis (LCH) is a clonal disease with focal or disseminated lesions that may compress the surrounding tissues, including the spinal cord. Because few reports have described the spinal symptoms as the first manifestation of pediatric LCH, the long-term neurological outcomes remain unclear. CASE REPORT AND LITERATURE REVIEW: We report a 21-month-old boy who presented with sudden-onset paraplegia. Imaging analyses revealed that osteolytic lesions and epidural tumors compressing the spinal cord at the T7-9 vertebrae...
June 12, 2018: Brain & Development
https://www.readbyqxmd.com/read/29906591/toxicity-of-nifurtimox-as-second-line-treatment-after-benznidazole-intolerance-in-patients-with-chronic-chagas-disease-when-available-options-fail
#15
Clara Crespillo-Andújar, Sandra Chamorro-Tojeiro, Francesca Norman, Begoña Monge-Maillo, Rogelio López-Velez, José A Pérez-Molina
OBJECTIVE: To describe the tolerability and rate of nifurtimox discontinuation when administered as a second-line treatment to patients with previous treatment interruptions due to adverse reactions with benznidazole. METHODS: Prospective cohort study of adult patients with chronic Chagas disease in a referral centre in Spain; study period July 2007 to July 2017. We analysed the tolerability profile and treatment interruption rate due to adverse reactions to nifurtimox in patients previously incompletely treated (less than 30 days) with benznidazole due to adverse reactions (ARs)...
June 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29906575/sodium-fluorescein-video-angiography-fl-vag-as-an-adjunct-to-resection-of-cerebral-arteriovenous-malformations
#16
Serrano-Rubio Alejandro, Ruiz-Treviño Armando S, Orenday-Barraza Jose M, Vázquez-Gregorio Rafael, Lee Angel, Nathal Edgar
OBJECT: The use of intraoperative fluorescence has proven to be a useful tool in multiple neurosurgical procedures with a potential utility in treating arteriovenous malformations (AVMs). The aim of this study was to characterize dynamic changes of an AVM using a microscope-integrated technique at the moment of performing an intraoperative Sodium fluorescein videoangiography (FL-VAG) at each of the resection phases. METHODS: Our study at the National Institute of Neurology and Neurosurgery-Mexico City, prospectively recruited twelve patients harboring an AVM, using FL-VAG as an ancillary technique for the resection of the lesion...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29905624/a-modified-posterior-c1-c2-fusion-technique-for-the-management-of-traumatic-odontoid-type-ii-fractures-by-using-intraoperative-spinal-navigation-mid-term-results
#17
Basem Ishak, Till Schneider, Valerie Gimmy, Andreas W Unterberg, Karl L Kiening
OBJECTIVES: To assess mid-term safety and efficacy of a modified Goel-Harms technique for the treatment of odontoid instabilities. DESIGN: Longitudinal prospective cohort study. SETTING: Urban Level 1 Trauma Center in Southwest Germany. PATIENTS/PARTICIPANTS: Orthopaedic and neurosurgical trauma patients older than 18 years admitted for ≤ 24 hours. MAIN OUTCOME MEASUREMENTS: The outcome was evaluated with respect to neurological outcome, radiological outcome and surgical complications...
June 4, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29905096/a-retrospective-study-of-horner-syndrome-in-australian-wild-birds-2010-2016
#18
Andrew G Hill
Horner syndrome was identified in 25 of 30 777 avian admissions to Currumbin Wildlife Hospital during 2010-2016. Unilateral ptosis and erection of facial feathers were distinct findings on physical examination and consistent across 9 species. Affected birds were biased toward adults (64%) suffering traumatic injuries (88%). Concurrent injuries requiring treatment were present in 38% of cases, and 76% had additional neurologic deficits. Prognosis for release was poor, with an overall success rate of 32%. Resolution of clinical signs increased to 44% with higher doses of meloxicam and required an average hospitalization of 22 days (range, 3-78 days)...
June 2018: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/29904974/anti-glycine-receptor-antibody-related-disease-a-case-series-and-literature-review
#19
Andrew Swayne, Linda Tjoa, Simon Broadley, Sasha Dionisio, David Gillis, Leslie Jacobson, Mark R Woodhall, Andrew McNabb, Daniel Schweitzer, Ben Tsang, Angela Vincent, Sarosh R Irani, Richard Wong, Patrick Waters, Stefan Blum
INTRODUCTION: Antibodies to glycine receptors (GlyR-Abs) were first defined in progressive encephalopathy with rigidity and myoclonus (PERM), but subsequently identified in other clinical presentations. We aimed to assess the clinical associations of all patients identified with GlyR-Abs in Queensland, Australia between April 2014 to May 2017, and compared these to cases reported in the literature. METHODS: A literature review identified the clinical features of all published GlyR-Ab positive cases through online databases...
June 15, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29904892/neuroimaging-abnormalities-in-neurological-patients-with-criminal-behavior
#20
REVIEW
R Ryan Darby
PURPOSE OF REVIEW: Criminal behavior occurs in previously law-abiding neurological patients, including patients with traumatic brain injury, focal brain lesions, and dementia. Neuroimaging abnormalities in these patients allow one to explore the potential neuroanatomical correlates of criminal behavior. However, this process has been challenging because (1) It is difficult to determine the temporal relationship between criminal behavior and neurological disease onset; (2) Abnormalities in several different brain regions have been associated with criminal behavior; and (3) It is difficult to quantify neuroimaging abnormalities in individual subjects...
June 14, 2018: Current Neurology and Neuroscience Reports
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