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https://www.readbyqxmd.com/read/28543787/accurate-determination-of-brain-metabolite-concentrations-using-eretic-as-external-reference
#1
Niklaus Zoelch, Andreas Hock, Susanne Heinzer-Schweizer, Nikolai Avdievitch, Anke Henning
Magnetic Resonance Spectroscopy (MRS) can provide in vivo metabolite concentrations in standard concentration units if a reliable reference signal is available. For (1) H MRS in the human brain, typically the signal from the tissue water is used as the (internal) reference signal. However, a concentration determination based on the tissue water signal most often requires a reliable estimate of the water concentration present in the investigated tissue. Especially in clinically interesting cases, this estimation might be difficult...
May 25, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28543439/metagenomic-profiling-of-the-microbial-freshwater-communities-in-two-bulgarian-reservoirs
#2
Ivan Iliev, Galina Yahubyan, Mariana Marhova, Elena Apostolova, Mariyana Gozmanova, Gana Gecheva, Sonya Kostadinova, Angelina Ivanova, Vesselin Baev
Microorganisms inhabiting freshwater environments are an integral part of the aquatic ecosystems. Very few data are available regarding the profiles of the microbial communities in the reservoirs in Bulgaria, despite their key role in the biogeochemical processes. In the present study, we provide the first comprehensive metagenomic analysis on the planktonic bacterial diversity of two large and economically important Bulgarian reservoirs (Batak and Tsankov Kamak) using next-generation sequencing of 16S ribosomal RNA gene (16S rRNA)...
May 22, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28543359/impact-of-resident-involvement-in-outpatient-otolaryngology-procedures-an-analysis-of-17-647-cases
#3
Andrew B Baker, Adrian A Ong, Brendan P O'Connell, Alexander D Sokohl, William B Clinkscales, Ted A Meyer
OBJECTIVE: This study examines the impact of resident physician participation on postoperative outcomes in outpatient otolaryngologic surgery. STUDY DESIGN: Retrospective cohort. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was queried for outpatient otolaryngologic procedures performed on adult patients. Cases were analyzed with the following cohorts: attending with resident or attending without resident...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28542567/effects-of-age-and-weaning-conditions-on-blood-indicators-of-oxidative-status-in-pigs
#4
Arnaud Buchet, Catherine Belloc, Mily Leblanc-Maridor, Elodie Merlot
Weaning is a source of social, nutritional and environmental disorders that challenge piglet health. This study assesses the relevance of using plasma indicators of oxidative status as biomarkers of health around weaning in pigs. Blood antioxidant potential (BAP), hydroperoxides (HPO), oxidative stress index (OSI, e.g. HPO/BAP), vitamin A and E concentrations were investigated in two different trials. Trial A was carried out in an experimental unit to investigate the effects of age (from 12 to 147 days of age), weaning (at 21 or 28 days of age) and management at weaning (in optimal (OC) or deteriorated (DC) conditions) on those parameters...
2017: PloS One
https://www.readbyqxmd.com/read/28542547/determination-of-diagnostic-standards-on-saturated-soil-extracts-for-cut-roses-grown-in-greenhouses
#5
John Jairo Franco-Hermida, María Fernanda Quintero, Raúl Iskander Cabrera, José Miguel Guzman
This work comprises the theoretical determination and validation of diagnostic standards for the analysis of saturated soil extracts for cut rose flower crops (Rosa spp.) growing in the Bogota Plateau, Colombia. The data included 684 plant tissue analyses and 684 corresponding analyses of saturated soil extracts, all collected between January 2009 and June 2013. The tissue and soil samples were selected from 13 rose farms, and from cultivars grafted on the 'Natal Briar' rootstock. These concurrent samples of soil and plant tissues represented 251 production units (locations) of approximately 10,000 m2 distributed across the study area...
2017: PloS One
https://www.readbyqxmd.com/read/28542386/correlation-between-plasma-endothelin-1-levels-and-severity-of-septic-liver-failure-quantified-by-maximal-liver-function-capacity-limax-test-a-prospective-study
#6
Magnus F Kaffarnik, Navid Ahmadi, Johan F Lock, Tilo Wuensch, Johann Pratschke, Martin Stockmann, Maciej Malinowski
AIM: To investigate the relationship between the degree of liver dysfunction, quantified by maximal liver function capacity (LiMAx test) and endothelin-1, TNF-α and IL-6 in septic surgical patients. METHODS: 28 septic patients (8 female, 20 male, age range 35-80y) were prospectively investigated on a surgical intensive care unit. Liver function, defined by LiMAx test, and measurements of plasma levels of endothelin-1, TNF-α and IL-6 were carried out within the first 24 hours after onset of septic symptoms, followed by day 2, 5 and 10...
2017: PloS One
https://www.readbyqxmd.com/read/28542315/attitudes-of-older-people-with-mild-dementia-and-mild-cognitive-impairment-and-their-relatives-about-falls-risk-and-prevention-a-qualitative-study
#7
Tamsin Peach, Kristian Pollock, Veronika van der Wardt, Roshan das Nair, Pip Logan, Rowan H Harwood
OBJECTIVE: To explore the perceptions of older people with mild dementia and mild cognitive impairment, and their family carers, about falling, falls risk and the acceptability of falls prevention interventions. DESIGN: Qualitative study involving thematic analysis of semi-structured interviews with patient and relative dyads. PARTICIPANTS AND SETTING: 20 patient/ relative dyads recruited from Memory Assessment Services and Falls Prevention Services in the United Kingdom...
2017: PloS One
https://www.readbyqxmd.com/read/28542184/estimation-of-the-cost-effectiveness-of-hiv-prevention-portfolios-for-people-who-inject-drugs-in-the-united-states-a-model-based-analysis
#8
Cora L Bernard, Douglas K Owens, Jeremy D Goldhaber-Fiebert, Margaret L Brandeau
BACKGROUND: The risks of HIV transmission associated with the opioid epidemic make cost-effective programs for people who inject drugs (PWID) a public health priority. Some of these programs have benefits beyond prevention of HIV-a critical consideration given that injection drug use is increasing across most United States demographic groups. To identify high-value HIV prevention program portfolios for US PWID, we consider combinations of four interventions with demonstrated efficacy: opioid agonist therapy (OAT), needle and syringe programs (NSPs), HIV testing and treatment (Test & Treat), and oral HIV pre-exposure prophylaxis (PrEP)...
May 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28541078/ensembles-in-medial-and-lateral-orbitofrontal-cortex-construct-cognitive-maps-emphasizing-different-features-of-the-behavioral-landscape
#9
Nina Lopatina, Brian F Sadacca, Michael A McDannald, Clay V Styer, Jacob F Peterson, Joseph F Cheer, Geoffrey Schoenbaum
The orbitofrontal cortex (OFC) has long been implicated in the ability to use the current value of expected outcomes to guide behavior. More recently, this specific role has been conceptualized as a special case of a more general function that OFC plays in constructing a "cognitive map" of the behavioral task space by labeling the current task state and learning relationships among task states. Here, we have used single unit recording data from 2 prior studies to examine whether and how information relating different states within and across trials is represented in medial versus lateral OFC in rats...
June 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28538939/quality-of-life-and-associated-characteristics-application-of-whoqol-bref-in-the-context-of-primary-health-care
#10
Celline Cardoso Almeida-Brasil, Micheline Rosa Silveira, Kátia Rodrigues Silva, Marina Guimarães Lima, Christina Danielli Coelho de Morais Faria, Claudia Lins Cardoso, Hans-Joachim Karl Menzel, Maria das Graças Braga Ceccato
This study aimed to identify the characteristics associated to quality of life (QOL) in users of four Basic Health Units (Unidades Básicas de Saúde, UBS) in Belo Horizonte, Minas Gerais. We conducted a cross-sectional study with 930 adult users enrolled in the selected UBS, using a questionnaire containing the WHOQOL-bref instrument and questions about sociodemographic characteristics, lifestyle and health conditions. Following descriptive analysis, we performed simple and multiple linear regression to evaluate the association between the exposure variables and the QOL domains...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28538641/prehospital-plasma-resuscitation-associated-with-improved-neurologic-outcomes-after-traumatic-brain-injury
#11
Matthew C Hernandez, Cornelius A Thiels, Johnathon M Aho, Elizabeth B Habermann, Martin D Zielinski, James A Stubbs, Donald H Jenkins, Scott P Zietlow
INTRODUCTION: Trauma related hypotension and coagulopathy worsen secondary brain injury in patients with traumatic brain injuries (TBI). Early damage control resuscitation with blood products may mitigate hypotension and coagulopathy. Preliminary data suggest resuscitation with plasma in large animals improve neurologic function after TBI; however, data in humans are lacking. METHODS: We retrospectively identified all poly-trauma patients age >15 years with head injuries undergoing prehospital resuscitation with blood products at a single level I trauma center from 01/2002 to 12/2013...
May 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28538612/scleral-contact-lenses-in-an-academic-oculoplastics-clinic-epidemiology-and-emerging-considerations
#12
Harinder S Chahal, Marcela Estrada, Christine W Sindt, Jacob A Boehme, Mark A Greiner, Jeffrey A Nerad, Keith D Carter, Richard C Allen, Erin M Shriver
PURPOSE: To describe the role and efficacy of scleral contact lenses (SCLs) in the treatment of progressive keratopathy in patients who have undergone periocular surgical procedures, to investigate the financial impact of these surgical interventions, and to demonstrate the role of oculoplastic surgery in improving scleral contact lens fit. METHODS: A retrospective medical record review was performed to identify patients who both received SCLs and were examined by the oculoplastics service at the University of Iowa between January 1990 and December 2015...
May 22, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538495/committee-opinion-no-701-choosing-the-route-of-hysterectomy-for-benign-disease
#13
(no author information available yet)
Hysterectomy is one of the most frequently performed surgical procedures in the United States. Selection of the route of hysterectomy for benign causes can be influenced by the size and shape of the vagina and uterus; accessibility to the uterus; extent of extrauterine disease; the need for concurrent procedures; surgeon training and experience; average case volume; available hospital technology, devices, and support; whether the case is emergent or scheduled; and preference of the informed patient. Vaginal and laparoscopic procedures are considered "minimally invasive" surgical approaches because they do not require a large abdominal incision and, thus, typically are associated with shortened hospitalization and postoperative recovery times compared with open abdominal hysterectomy...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28538491/committee-opinion-no-701-summary-choosing-the-route-of-hysterectomy-for-benign-disease
#14
(no author information available yet)
Hysterectomy is one of the most frequently performed surgical procedures in the United States. Selection of the route of hysterectomy for benign causes can be influenced by the size and shape of the vagina and uterus; accessibility to the uterus; extent of extrauterine disease; the need for concurrent procedures; surgeon training and experience; average case volume; available hospital technology, devices, and support; whether the case is emergent or scheduled; and preference of the informed patient. Vaginal and laparoscopic procedures are considered "minimally invasive" surgical approaches because they do not require a large abdominal incision and, thus, typically are associated with shortened hospitalization and postoperative recovery times compared with open abdominal hysterectomy...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28538445/a-national-survey-on-the-use-of-immersive-simulation-for-interprofessional-education-in-physical-therapist-education-programs
#15
Brad Stockert, Patricia J Ohtake
INTRODUCTION: There is growing recognition that collaborative practice among healthcare professionals is associated with improved patient outcomes and enhanced team functioning, but development of collaborative practitioners requires interprofessional education (IPE). Immersive simulation, a clinically relevant experience that deeply engages the learner in realistic clinical environments, is used increasingly for IPE. The purpose of this study was to assess the use of immersive simulation as a strategy for IPE in physical therapist (PT) education programs...
May 20, 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28538427/return-on-investment-of-advanced-practice-medical-degrees-nps-vs-pas
#16
Christopher K Craig, James H Holmes, Jeffery E Carter
As the United States faces a predicted physician shortage over the next 2 decades, physician assistants (PAs) and NPs are expected to fill the void. At the same time, because education is expensive, student loan and tuition increases have many potential applicants assessing differences in reimbursement and wondering about their return on investment (ROI). An analysis compared PA and NP salaries by incorporating national salary data, federal income tax, and student loans for a comparative analysis of each career pathway...
June 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28538212/a-global-comparison-of-the-cost-of-patented-cancer-drugs-in-relation-to-global-differences-in-wealth
#17
Daniel A Goldstein, Jonathon Clark, Yifan Tu, Jie Zhang, Fenqi Fang, Robert Goldstein, Salomon M Stemmer, Eli Rosenbaum
INTRODUCTION: There are major differences in cancer drug prices around the world. However, the patterns of affordability of these drugs are poorly understood. The objective of this study was to compare patterns of affordability of cancer drugs in Australia, China, India, Israel, South Africa, the United Kingdom, and the United States. RESULTS: Cancer drug prices are highest in the United States. Cancer drugs are the least affordable in India by a large margin. Despite lower prices than in the USA, cancer drugs are less affordable in middle-income countries than in high-income countries...
May 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28536094/using-beta-version-mhealth-technology-for-team-based-care-management-to-support-stroke-prevention-an-assessment-of-utility-and-challenges
#18
Magaly Ramirez, Shinyi Wu, Gery Ryan, Amytis Towfighi, Barbara G Vickrey
BACKGROUND: Beta versions of health information technology tools are needed in service delivery models with health care and community partnerships to confirm the key components and to assess the performance of the tools and their impact on users. We developed a care management technology (CMT) for use by community health workers (CHWs) and care managers (CMs) working collaboratively to improve risk factor control among recent stroke survivors. The CMT was expected to enhance the efficiency and effectiveness of the CHW-CM team...
May 23, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28535916/efficiency-of-personal-dosimetry-methods-in-vascular-interventional-radiology
#19
Fernando Antonio Bacchim Neto, Allan Felipe Fattori Alves, Yvone Maria Mascarenhas, Guilherme Giacomini, Nadine Helena Pelegrino Bastos Maués, Patrícia Nicolucci, Carlos Clayton Macedo de Freitas, Matheus Alvarez, Diana Rodrigues de Pina
PURPOSE: The aim of the present study was to determine the efficiency of six methods for calculate the effective dose (E) that is received by health professionals during vascular interventional procedures. METHODS: We evaluated the efficiency of six methods that are currently used to estimate professionals' E, based on national and international recommendations for interventional radiology. Equivalent doses on the head, neck, chest, abdomen, feet, and hands of seven professionals were monitored during 50 vascular interventional radiology procedures...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28534713/the-influence-of-thermal-comfort-on-the-quality-of-life-of-nursing-home-residents
#20
Ana Mendes, Ana Luísa Papoila, Pedro Carreiro-Martins, Lívia Aguiar, Stefano Bonassi, Iolanda Caires, Teresa Palmeiro, Álvaro Silva Ribeiro, Paula Neves, Cristiana Pereira, Amália Botelho, Nuno Neuparth, João Paulo Teixeira
Thermal comfort (TC) parameters were measured in 130 rooms from nursing homes (NH), following ISO 7730:2005 in order to evaluate the influence of winter season TC indices on quality of life (QoL) in older individuals. Mean radiant temperature (mrT), predicted mean vote (PMV) and predicted percent of dissatisfied people (PPD) indices, and the respective measurement uncertainties were calculated using Monte Carlo Method. The WHOQOL-BREF questionnaire was conducted from September 2012 to April 2013, during the winter season TC sampling campaign...
May 23, 2017: Journal of Toxicology and Environmental Health. Part A
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