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https://www.readbyqxmd.com/read/29332161/the-computed-tomography-adrenal-wash-out-analysis-properly-classifies-cortisol-secreting-adrenocortical-adenomas
#1
Anne-Laure Humbert, Guillaume Lecoanet, Sophie Moog, Fehd Bouderraoui, Laurent Bresler, Jean-Michel Vignaud, Elodie Chevalier, Laurent Brunaud, Marc Klein, Thomas Cuny
PURPOSE: Adrenocortical lesions are characterized through imaging, hormonal and histopathological analysis. Our aim was to compare the radiological features of adrenocortical lesions with their cortisol-secreting status and histopathological Weiss score. METHODS: Seventy five patients operated between 2004 and 2016 in the University Hospital of Nancy for either adrenocortical carcinomas (ACC) or adrenocortical adenomas (ACA) were enrolled in this study. We collected cortisol parameters, Computed Tomography (CT) scans (unenhanced density, wash-out (WO) analysis) and 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) datas...
January 13, 2018: Endocrine
https://www.readbyqxmd.com/read/29332119/autofluorescence-of-skin-advanced-glycation-end-products-as-a-risk-factor-for-open-angle-glaucoma-the-alienor-study
#2
Cedric Schweitzer, Audrey Cougnard-Gregoire, Vincent Rigalleau, Jean-Francois Dartigues, Florence Malet, Marie-Benedicte Rougier, Marie-Noelle Delyfer, Catherine Helmer, Jean-Francois Korobelnik, Cecile Delcourt
Purpose: To analyze the association between skin autofluorescence (sAF), estimating tissue accumulation of advanced glycation end-products (AGEs), and open angle glaucoma (OAG) in an elderly population. Methods: The Antioxydants, Lipides Essentiels, Nutrition and maladies OculaiRes (ALIENOR) study is an on-going epidemiologic population-based study on age-related eye diseases. In 2009 to 2010, 624 subjects, aged 74 years or older, were recruited. All subjects underwent a complete eye examination, including optic disc color photography and spectral-domain optical coherence tomography (SD-OCT) examination...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29331893/ambient-volatile-organic-compounds-vocs-in-communities-of-the-athabasca-oil-sands-region-sources-and-screening-health-risk-assessment
#3
Md Aynul Bari, Warren B Kindzierski
An investigation of ambient levels and sources of volatile organic compounds (VOCs) and associated public health risks was carried out at two northern Alberta oil sands communities (Fort McKay and Fort McMurray located < 25 km and >30 km from oil sands development, respectively) for the period January 2010-March 2015. Levels of total detected VOCs were comparatively similar at both communities (Fort McKay: geometric mean = 22.8 μg/m3, interquartile range, IQR = 13.8-41 μg/m3); (Fort McMurray: geometric mean = 23...
January 11, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29329574/microcephaly-epidemic-related-to-the-zika-virus-and-living-conditions-in-recife-northeast-brazil
#4
Wayner Vieira de Souza, Maria de Fátima Pessoa Militão de Albuquerque, Enrique Vazquez, Luciana Caroline Albuquerque Bezerra, Antonio da Cruz Gouveia Mendes, Tereza Maciel Lyra, Thalia Velho Barreto de Araujo, André Luiz Sá de Oliveira, Maria Cynthia Braga, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Amanda Priscila de Santana Cabral Silva, Laura Rodrigues, Celina Maria Turchi Martelli
BACKGROUND: Starting in August 2015, there was an increase in the number of cases of neonatal microcephaly in Northeast Brazil. These findings were identified as being an epidemic of microcephaly related to Zika virus (ZIKV) infection. The present study aims to analyse the spatial distribution of microcephaly cases in Recife (2015-2016), which is in Northeast Brazil, and its association with the living conditions in this city. METHODS: This was an ecological study that used data from reported cases of microcephaly from the State Health Department of Pernambuco (August 2015 to July 2016)...
January 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29326410/-factors-predicting-the-interface-pressure-related-to-pressure-injury-in-intensive-care-unit-patients
#5
Ji Seon Shine, Soo Jin Kim, Ji Hyun Lee, Mi Yu
PURPOSE: Interface pressure is a factor that contributes to the occurrence of pressure injuries. This study aimed to investigate interface pressure at common sites of pressure injury (occipital, gluteal and peritrochanteric areas), to explore the relationships among risk factors, skin condition and interface pressure, and to identify risk factors influencing interface pressure. METHODS: A total of 100 patients admitted to the intensive care unit were enrolled at a tertiary teaching hospital in Korea...
December 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/29324936/the-impact-of-lung-perfusion-scintigraphy-in-the-emergency-management-of-patients-with-suspected-pulmonary-embolism
#6
Cristina Ferrari, Alessandra Cimino, Giacomo Bianco, Francesca Iuele, Alessandra Di Palo, Margherita Fanelli, Artor Niccoli-Asabella, Giuseppe Rubini
OBJECTIVE: Pulmonary Embolism (PE) is an emergency condition that requires immediate treatment. As the symptoms and the risk factors are nonspecific, PE differential diagnosis is often required. Even if angio-CT is considered the gold standard for PE diagnosis, the frequent allergic condition and/or chronic renal failure of patients make, in most cases, not possible the use of contrast enhancement in emergency with even more increasing use of Lung Perfusion Scintigraphy (LPS), as a simple and fast examination with no preparation/contraindication...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29324512/exercise-capacity-in-patients-with-the-total-artificial-heart
#7
Justin M Canada, Ronald K Evans, Antonio Abbate, Ross Arena, Daniel G Tang, Vigneshwar Kasirajan, Keyur B Shah
There is a dearth of information regarding the functional abilities of patients with the total artificial heart (TAH). Increased utilization of the TAH and patient discharge to home with the portable unit necessitates a shift in focus to quality of life, which includes quantifying and ultimately optimizing functional capacity. To date, only single-patient case studies have described the exercise response of the TAH patient. Fourteen patients with the TAH underwent cardiopulmonary exercise testing with concurrent analysis of TAH device function...
January 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29322987/complications-related-to-sitting-position-during-pediatric-neurosurgery-an-institutional-experience-and-review-of-literature
#8
Priyanka Gupta, Girija P Rath, Hemanshu Prabhakar, Parmod K Bithal
BACKGROUND: Sitting position is preferred during posterior fossa surgeries as it provides better anatomical orientation and a clear surgical field. However, its use has been declining due to its propensity to cause life-threatening complications. This study was carried out to analyze the perioperative complications and postoperative course of children who underwent neurosurgery in sitting position. MATERIALS AND METHODS: Medical records of 97 children (<18 years) who underwent neurosurgery in sitting position over a period of 12 years, were retrospectively analyzed...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29319585/which-us-states-pose-the-greatest-threats-to-military-readiness-and-public-health-public-health-policy-implications-for-a-cross-sectional-investigation-of-cardiorespiratory-fitness-body-mass-index-and-injuries-among-us-army-recruits
#9
Daniel B Bornstein, George L Grieve, Morgan N Clennin, Alexander C McLain, Laurie P Whitsel, Michael W Beets, Keith G Hauret, Bruce H Jones, Mark A Sarzynski
OBJECTIVE: Many states in the southern region of the United States are recognized for higher rates of obesity, physical inactivity, and chronic disease. These states are therefore recognized for their disproportionate public health burden. The purpose of this study was to investigate state-level distributions of cardiorespiratory fitness, body mass index (BMI), and injuries among US Army recruits in order to determine whether or not certain states may also pose disproportionate threats to military readiness and national security...
January 9, 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29316937/estimate-of-incidence-and-cost-of-recreational-waterborne-illness-on-united-states-surface-waters
#10
Stephanie DeFlorio-Barker, Coady Wing, Rachael M Jones, Samuel Dorevitch
BACKGROUND: Activities such as swimming, paddling, motor-boating, and fishing are relatively common on US surface waters. Water recreators have a higher rate of acute gastrointestinal illness, along with other illnesses including respiratory, ear, eye, and skin symptoms, compared to non-water recreators. The quantity and costs of such illnesses are unknown on a national scale. METHODS: Recreational waterborne illness incidence and severity were estimated using data from prospective cohort studies of water recreation, reports of recreational waterborne disease outbreaks, and national water recreation statistics...
January 9, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29316935/estimating-the-returns-to-united-kingdom-publicly-funded-musculoskeletal-disease-research-in-terms-of-net-value-of-improved-health-outcomes
#11
Matthew Glover, Erin Montague, Alexandra Pollitt, Susan Guthrie, Stephen Hanney, Martin Buxton, Jonathan Grant
BACKGROUND: Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved health outcomes in the United Kingdom. METHODS: To calculate the economic returns from MSD-related research in the United Kingdom, we estimated (1) the public and charitable expenditure on MSD-related research in the United Kingdom between 1970 and 2013; (2) the net monetary benefit (NMB), derived from the health benefit in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of £25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1994 to 2013; (3) the proportion of NMB attributable to United Kingdom research; and (4) the elapsed time between research funding and health gain...
January 10, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29316589/a-comparison-of-relative-value-units-in-primary-versus-revision-total-ankle-arthroplasty
#12
Nipun Sodhi, Benjamin Yao, Jared M Newman, Michael Jawad, Anton Khlopas, Assem A Sultan, Suela Lamaj, George A Beyer, Alyeesha B Wilhelm, Michael A Mont
INTRODUCTION: To determine the effort required to provide a service, the United States Medicare uses Relative Value Units (RVUs). Consequently, higher RVUs are assigned to the procedures or services that require more effort, which ultimately means the physician will be properly compensated for the additional effort required. In total ankle arthroplasty (TAA), revision cases usually are more technically challenging and require more effort than primary TAA. Therefore, the purpose of this study was to compare the: 1) RVUs; 2) length-of-surgery; 3) RVU per unit of time between primary and revision total ankle arthroplasty; and 4) the individualized idealized surgeon annual cost difference analysis...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29316514/risk-based-cost-benefit-analysis-for-evaluating-microbial-risk-mitigation-in-a-drinking-water-system
#13
Viktor Bergion, Andreas Lindhe, Ekaterina Sokolova, Lars Rosén
Waterborne outbreaks of gastrointestinal diseases can cause large costs to society. Risk management needs to be holistic and transparent in order to reduce these risks in an effective manner. Microbial risk mitigation measures in a drinking water system were investigated using a novel approach combining probabilistic risk assessment and cost-benefit analysis. Lake Vomb in Sweden was used to exemplify and illustrate the risk-based decision model. Four mitigation alternatives were compared, where the first three alternatives, A1-A3, represented connecting 25, 50 and 75%, respectively, of on-site wastewater treatment systems in the catchment to the municipal wastewater treatment plant...
December 27, 2017: Water Research
https://www.readbyqxmd.com/read/29315204/moral-distress-model-reconstructed-using-grounded-theory
#14
Hsun-Kuei Ko, Chi-Chun Chin, Min-Tao Hsu
BACKGROUND: The problems of nurse burnout and manpower shortage relate to moral distress. Thus, having a good understanding of moral distress is critical to developing strategies that effectively improve the clinical ethical climate and improve nursing retention in Taiwan. PURPOSE: The aim of this study was to reconstruct the model of moral distress using the grounded theory. METHODS: Twenty-five staff nurses at work units who attend to the needs of adult, pediatric, acute, and critical disease or end-of-life-care patients were recruited as participants using theoretical sampling from three teaching hospitals in Taiwan...
February 2018: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29314505/daily-home-bnp-monitoring-in-heart-failure-for-prediction-of-impending-clinical-deterioration-results-from-the-home-hf-study
#15
Kenneth McDonald, Richard Troughton, Ulf Dahlström, Henry Dargie, Henry Krum, Peter van der Meer, Theresa McDonagh, John J Atherton, Ken Kupfer, Richard C San George, Mark Richards, Robert Doughty
BACKGROUND: Serial measurement of natriuretic peptides may guide management in heart failure (HF) patients. In previous trials, natriuretic peptides were infrequently monitored, which may undervalue the benefit of this approach. METHODS AND RESULTS: HOME was an adaptive three-arm randomized clinical study to test whether home monitoring of BNP could reduce HF-related death, hospitalization due to acute decompensated HF (ADHF), and ADHF treated with intravenous diuretics in the emergency department or outpatient setting...
January 4, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29314261/future-osteoporotic-fracture-risk-related-to-lumbar-vertebral-trabecular-attenuation-measured-at-routine-body-ct
#16
Scott J Lee, Peter M Graffy, Ryan D Zea, Timothy J Ziemlewicz, Perry J Pickhardt
We sought to determine if vertebral trabecular attenuation values measured on routine body CT scans obtained for a variety of unrelated indications can predict future osteoporotic fractures at multiple skeletal sites. For this HIPAA-compliant and IRB-approved retrospective cohort study, trabecular attenuation of the first lumbar vertebra was measured in 1966 consecutive older adults who underwent chest and/or abdominal CT at a single institution over the course of one year. New pathologic fragility fractures that occurred after a patient's CT study date were identified through an electronic health record database query using ICD-9 codes for vertebral, hip, and extremity fractures...
January 3, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29313668/high-thermoelectric-performance-of-in4se3-based-materials-and-the-influencing-factors
#17
Xin Yin, Jing-Yuan Liu, Ling Chen, Li-Ming Wu
Materials that can directly convert electricity into heat, i.e., thermoelectric materials, have attracted renewed attention globally for sustainable energy applications. As one of the state-of-the-art thermoelectric materials, In4Se3 features an interesting crystal structure of quasi-two-dimensional sheets comprising In/Se chains that provide a platform to achieve a Peierls distortion and support a charge density wave instability. Single-crystal In4Se3-δ (δ = 0.65) shows strong anisotropy in its thermoelectric properties with a very high ZT of 1...
January 9, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29306228/emergency-coronary-bypass-surgery-in-patients-under-the-influence-of-dualantiplatelet-therapy-effects-of-tranexamic-acid-and-desmopressin-acetate
#18
Gökalp Altun, Doğuş Hemşinli, Zerrin Pulathan, Ali Civelek
Background/aim: Bleeding in patients undergoing coronary artery bypass grafting (CABG) while using dual antiplatelet therapy (DAPT) is a cause of significant morbidity and mortality. The aim of this study is to examine the perioperative hemostatic effects of tranexamic acid (TnX-A) and desmopressin acetate (Des) in these patients. Materials and methods: This clinical study was planned in a prospective and randomized manner. Fifty-four patients were enrolled and classified into 4 different groups. They were compared in terms of various bleeding and transfusion parameters...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29305515/sapovirus-in-wastewater-treatment-plants-in-tunisia-prevalence-removal-and-genetic-characterization
#19
Miguel F Varela, Imen Ouardani, Tsuyoshi Kato, Syunsuke Kadoya, Mahjoub Aouni, Daisuke Sano, Jesús L Romalde
Sapovirus (SaV), from the Caliciviridae family, are enteric viruses that cause acute gastroenteritis. SaV are shed at high concentrations with faeces to wastewater, which are usually discharged at the aquatic environments or reused for irrigation without efficient treatments. This study analyzed the incidence of human SaV in four wastewater treatment plants from Tunisia during a period of 13 months (December 2009 to December 2010). Detection and quantification were carried out using RT-qPCR methods, obtaining a prevalence of 39...
January 5, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29304947/trading-bankruptcy-for-health-a-discrete-choice-experiment
#20
Mark G Shrime, Milton C Weinstein, James K Hammitt, Jessica L Cohen, Joshua A Salomon
BACKGROUND: Although nearly two-third of bankruptcy in the United States is medical in origin, a common assumption is that individuals facing a potentially lethal disease opt for cure at any cost. This assumption has never been tested, and knowledge of how the American population values a trade-off between cure and bankruptcy is unknown. OBJECTIVES: To determine the relative importance among the general American population of improved health versus improved financial risk protection, and to determine the impact of demographics on these preferences...
January 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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