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Magnesium deficiency

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https://www.readbyqxmd.com/read/29160809/evaluation-of-dietary-intakes-and-supplement-use-in-paralympic-athletes
#1
Robyn F Madden, Jane Shearer, Jill A Parnell
Dietary intakes and supplement use in Paralympic athletes remains largely unexplored, and specialized recommendations are lacking. The aim of this study was to evaluate nutrient intakes and supplement use in high-performance athletes with physical disabilities using three-day food records and a validated dietary supplement use questionnaire. A secondary aim examined gender differences in nutrient and supplement intakes. Male (n = 18) and female (n = 22) athletes were recruited from nine Paralympic sports through sporting organizations, coaches, and social media...
November 21, 2017: Nutrients
https://www.readbyqxmd.com/read/29129401/deletion-of-claudin-10-rescues-claudin-16-deficient-mice-from-hypomagnesemia-and-hypercalciuria
#2
Tilman Breiderhoff, Nina Himmerkus, Hoora Drewell, Allein Plain, Dorothee Günzel, Kerim Mutig, Thomas E Willnow, Dominik Müller, Markus Bleich
The tight junction proteins claudin-10 and -16 are crucial for the paracellular reabsorption of cations along the thick ascending limb of Henle's loop in the kidney. In patients, mutations in CLDN16 cause familial hypomagnesemia with hypercalciuria and nephrocalcinosis, while mutations in CLDN10 impair kidney function. Mice lacking claudin-16 display magnesium and calcium wasting, whereas absence of claudin-10 results in hypermagnesemia and interstitial nephrocalcinosis. In order to study the functional interdependence of claudin-10 and -16 we generated double-deficient mice...
November 10, 2017: Kidney International
https://www.readbyqxmd.com/read/29120789/laser-induced-breakdown-spectroscopy-libs-for-rapid-analysis-of-ash-potassium-and-magnesium-in-gluten-free-flours
#3
Maria Markiewicz-Keszycka, Maria P Casado-Gavalda, Xavier Cama-Moncunill, Raquel Cama-Moncunill, Yash Dixit, Patrick J Cullen, Carl Sullivan
Gluten free (GF) diets are prone to mineral deficiency, thus effective monitoring of the elemental composition of GF products is important to ensure a balanced micronutrient diet. The objective of this study was to test the potential of laser-induced breakdown spectroscopy (LIBS) analysis combined with chemometrics for at-line monitoring of ash, potassium and magnesium content of GF flours: tapioca, potato, maize, buckwheat, brown rice and a GF flour mixture. Concentrations of ash, potassium and magnesium were determined with reference methods and LIBS...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29093983/the-importance-of-magnesium-in-clinical-healthcare
#4
REVIEW
Gerry K Schwalfenberg, Stephen J Genuis
The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions...
2017: Scientifica
https://www.readbyqxmd.com/read/29093028/genome-wide-meta-analysis-unravels-interactions-between-magnesium-homeostasis-and-metabolic-phenotypes
#5
Tanguy Corre, Francisco J Arjona, Caroline Hayward, Sonia Youhanna, Jeroen H F de Baaij, Hendrica Belge, Nadine Nägele, Huguette Debaix, Maxime G Blanchard, Michela Traglia, Sarah E Harris, Sheila Ulivi, Rico Rueedi, David Lamparter, Aurélien Macé, Cinzia Sala, Stefania Lenarduzzi, Belen Ponte, Menno Pruijm, Daniel Ackermann, Georg Ehret, Daniela Baptista, Ozren Polasek, Igor Rudan, Toby W Hurd, Nicholas D Hastie, Veronique Vitart, Geràrd Waeber, Zoltán Kutalik, Sven Bergmann, Rosa Vargas-Poussou, Martin Konrad, Paolo Gasparini, Ian J Deary, John M Starr, Daniela Toniolo, Peter Vollenweider, Joost G J Hoenderop, René J M Bindels, Murielle Bochud, Olivier Devuyst
Magnesium (Mg(2+)) homeostasis is critical for metabolism. However, the genetic determinants of the renal handling of Mg(2+), which is crucial for Mg(2+) homeostasis, and the potential influence on metabolic traits in the general population are unknown. We obtained plasma and urine parameters from 9099 individuals from seven cohorts, and conducted a genome-wide meta-analysis of Mg(2+) homeostasis. We identified two loci associated with urinary magnesium (uMg), rs3824347 (P=4.4×10(-13)) near TRPM6, which encodes an epithelial Mg(2+) channel, and rs35929 (P=2...
November 1, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29090711/the-effect-of-dietary-magnesium-and-caseinphosphopeptides-on-bone-metabolism-in-rats
#6
Guo Liu, Jianyin Miao, Shengwei Sun, Zhen Luo, Zumeng Xia, Baoyan Guo, Fei Liu, Yunjiao Chen, Danyang Ying, Benchun Miao, Yong Cao
The effect of dietary magnesium (Mg) or caseinphosphopeptides (CPPs) on bone metabolism has been reported. However, few studies have investigated the effects of simultaneous supplementation of Mg and CPPs. Sixty-three 3-week-old Sprague-Dawley male rats were divided into seven groups and fed a specified diet for 45 days. Body characteristics, bone physicochemical indicators, and bone metabolism indicators relative to bone metabolism were analyzed. We found that, first, a dietary Mg deficiency resulted in increased bone formation and decreased bone resorption...
November 1, 2017: Food & Function
https://www.readbyqxmd.com/read/29089939/optimization-of-culture-medium-enhances-viable-biomass-production-and-biocontrol-efficacy-of-the-antagonistic-yeast-candida-diversa
#7
Jia Liu, Guangkun Li, Yuan Sui
Viable biomass production is a key determinant of suitability of antagonistic yeasts as potential biocontrol agents. This study investigated the effects of three metal ions (magnesium, ferrous, and zinc) on biomass production and viability of the antagonistic yeast, Candida diversa. Using response surface methodology to optimize medium components, a maximum biomass was obtained, when the collective Mg(2+), Fe(2+), and Zn(2+) concentrations were adjusted in a minimal mineral (MM) medium. Compared with the unmodified MM, and three ion-deficient MM media, yeast cells cultured in the three ion-modified MM medium exhibited a lower level of cellular oxidative damage, and a higher level of antioxidant enzyme activity...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29065862/correction-to-effects-of-dietary-gelatin-hydrolysates-on-bone-mineral-density-in-magnesium-deficient-rats
#8
Teruyuki Noma, Satoshi Takasugi, Miho Shioyama, Taketo Yamaji, Hiroyuki Itou, Yoshio Suzuki, Keishoku Sakuraba, Keisuke Sawaki
No abstract text is available yet for this article.
October 24, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29063903/iron-and-vitamin-d-levels-among-autism-spectrum-disorders-children
#9
Abdulbari Bener, Azhar O Khattab, Dinesh Bhugra, Georg F Hoffmann
AIM: The aim of this study was to investigate iron deficiency anemia and Vitamin D deficiency among autism children and to assess the importance of risk factors (determinants). SUBJECTS AND METHODS: This was a case-control study conducted among children suffering from autism at the Hamad Medical Corporation in Qatar. A total of 308 cases and equal number of controls were enrolled. The Autism Diagnostic Observation Schedule-Generic was the instrument used for diagnosis of Autism...
October 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/29062185/a-case-of-renal-tubular-acidosis-with-sjogren-s-syndrome-showing-paradoxical-block-of-pth-due-to-severe-hypomagnesemia
#10
B Vinodh Kumar, M Sivalingam, G Shiva Kumaran, Balambal Balakrishnan
Distal renal tubular acidosis (RTA) manifests either as Complete/Classical form or Incomplete/Latent Form. Distal RTA causes normal anion gap metabolic acidosis and hypokalemia. Interstitial Nephritis is the most frequent renal manifestation of Sjogren's, which presents as Distal RTA in 25-40% of patients with Sjogren's syndrome. Magnesium deficiency is frequently associated with hypokalemia. Although serum calcium is the main physiological control for the secretion of parathyroid hormone (PTH) by the parathyroid, serum magnesium can also exert similar effects...
October 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/29036357/chronic-magnesium-deficiency-and-human-disease-time-for-reappraisal
#11
Adel A A Ismail, Yasmin Ismail, Abbas A Ismail
Numerous epidemiological, experimental and clinical studies over the last 30 years have consistently shown that chronic magnesium deficiency is associated with and/or exacerbates a number of major disorders (table 1). Yet chronic magnesium deficiency is not widely recognised and a major reason for this failure is that serum magnesium levels do not accurately reflect body magnesium stores. Specifically, in chronic magnesium deficiency, serum magnesium levels are often within the normal reference range (usually lowest quartile) and may not progress to overt hypomagnesaemia...
September 22, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29026589/a-retrospective-analysis-of-biochemical-and-haematological-parameters-in-patients-with-eating-disorders
#12
Leanne J Barron, Robert F Barron, Jeremy C S Johnson, Ingrid Wagner, Cameron J B Ward, Shannon R B Ward, Faye M Barron, Warren K Ward
BACKGROUND: The objective of the study was to determine whether levels of biochemical and haematological parameters in patients with eating disorders (EDs) varied from the general population. Whilst dietary restrictions can lead to nutritional deficiencies, specific abnormalities may be relevant to the diagnosis, pathogenesis and treatment of EDs. METHODS: With ethics approval and informed consent, a retrospective chart audit was conducted of 113 patients with EDs at a general practice in Brisbane, Australia...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28990453/deficiencies-of-magnesium-replacement-in-the-critically-ill
#13
Klayton M Ryman, Todd W Canada
No abstract text is available yet for this article.
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28933510/-unusual-case-of-struvite-urolithiasis-in-a-dog-a-case-report-ein-fallbericht
#14
Julia K Mack, Ellen Kienzle
A dog was referred for nutrition consultation after surgical removal of struvite uroliths from the bladder. Inspection of the dog's current ration revealed a pronounced vitamin-A deficiency together with a marked deficiency of protein, phosphorus and magnesium. Therefore, a supersaturation of the urine with ammonium, magnesium and phosphate, the three constituents of struvite, as a cause of struvite calculi formation appears rather unlikely. Vitamin-A deficiency can promote urinary infections and consequently struvite stone formation because of the lack of the protective effect of vitamin A on the epithelia of the urinary tract...
September 20, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28920941/reversible-magnesium-and-aluminium-ions-insertion-in-cation-deficient-anatase-tio2
#15
Toshinari Koketsu, Jiwei Ma, Benjamin J Morgan, Monique Body, Christophe Legein, Walid Dachraoui, Mattia Giannini, Arnaud Demortière, Mathieu Salanne, François Dardoize, Henri Groult, Olaf J Borkiewicz, Karena W Chapman, Peter Strasser, Damien Dambournet
In contrast to monovalent lithium or sodium ions, the reversible insertion of multivalent ions such as Mg(2+) and Al(3+) into electrode materials remains an elusive goal. Here, we demonstrate a new strategy to achieve reversible Mg(2+) and Al(3+) insertion in anatase TiO2, achieved through aliovalent doping, to introduce a large number of titanium vacancies that act as intercalation sites. We present a broad range of experimental and theoretical characterizations that show a preferential insertion of multivalent ions into titanium vacancies, allowing a much greater capacity to be obtained compared to pure TiO2...
November 2017: Nature Materials
https://www.readbyqxmd.com/read/28915968/magnesium-to-counteract-elastin-degradation-and-vascular-calcification-in-chronic-obstructive-pulmonary-disease
#16
Rob Janssen
Accelerated elastin degradation is an important pathogenic mechanism in chronic obstructive pulmonary disease (COPD) leading to irreversible lung function loss and cardiovascular comorbidities. The rate of elastin breakdown is a predictor of mortality in patients with COPD. Decelerating elastinolysis might be an attractive therapeutic target in this debilitating condition. Vascular calcification starts in the elastin network of the arterial wall and is enhanced in patients with COPD. Elastin calcification is accompanied by an upregulation of matrix metalloproteinase gene expression and consequently a shift in the elastase/anti-elastase balance towards degradation...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28877896/intake-of-potassium-and-magnesium-enriched-salt-improves-functional-outcome-after-stroke-a-randomized-multicenter-double-blind-controlled-trial
#17
Wen-Harn Pan, Ying-Ho Lai, Wen-Ting Yeh, Jiunn-Rong Chen, Jiann-Shing Jeng, Chyi-Huey Bai, Ruey-Tay Lin, Tsong-Hai Lee, Ku-Chou Chang, Huey-Juan Lin, Chin-Fu Hsiao, Chang-Ming Chern, Li-Ming Lien, Chung-Hsiang Liu, Wei-Hung Chen, Anna Chang
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need. Our previous intervention trial in elderly subjects successfully used salt as a carrier for potassium, demonstrating a 41% reduction in cardiovascular mortality by switching to potassium-enriched salt. Dietary magnesium has been associated with lowered diabetes and/or stroke risk in humans and with neuroprotection in animals.Objective: Because a large proportion of Taiwanese individuals are in marginal deficiency states for potassium and for magnesium and salt is a good carrier for minerals, it is justifiable to study whether further enriching salt with magnesium at an amount near the Dietary Reference Intake (DRI) amount may provide additional benefit for stroke recovery...
September 6, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28871398/effect-of-pulsed-electric-fields-pef-on-accumulation-of-magnesium-in-lactobacillus-rhamnosus-b-442-cells
#18
Małgorzata Góral, Urszula Pankiewicz
The aim of this study was to determine the effect of pulsed electric fields (PEF) on accumulation of magnesium ions in Lactobacillus rhamnosus B 442 cells. Under optimized conditions, this is, on 15 min exposure of the 20 h grown culture to PEF of the 2.0 kV/cm and 20 µs pulse width at concentration 400 μg Mg(2+)/mL medium, accumulation of magnesium in the biomass reached maximum 4.28 mg/g d.m. Optimization of PEF parameters caused an increase of magnesium concentration in the cells by 220% in comparison to the control not treated with PEF...
October 2017: Journal of Membrane Biology
https://www.readbyqxmd.com/read/28871377/the-maize-cora-mrs2-mgt-type-mg-transporter-zmmgt10-responses-to-magnesium-deficiency-and-confers-low-magnesium-tolerance-in-transgenic-arabidopsis
#19
Hongyou Li, Ning Wang, Jianzhou Ding, Chan Liu, Hanmei Du, Kaifeng Huang, Moju Cao, Yanli Lu, Shibin Gao, Suzhi Zhang
ZmMGT10 was specifically expressed in maize roots and induced by a deficiency of magnesium. Overexpression of ZmMGT10 restored growth deficiency of the Salmonella typhimurium MM281 strain and enhanced the tolerance in Arabidopsis to stress induced by low magnesium levels by increasing uptake of Mg(2+) via roots. CorA/MRS2/MGT-type Mg(2+) transporters play a significant role in maintaining magnesium (Mg) homeostasis in plants. Although the maize CorA/MRS2/MGT family comprises of 12 members, currently no member has been functionally characterized...
October 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28870199/effects-of-dietary-gelatin-hydrolysates-on-bone-mineral-density-in-magnesium-deficient-rats
#20
Teruyuki Noma, Satoshi Takasugi, Miho Shioyama, Taketo Yamaji, Hiroyuki Itou, Yoshio Suzuki, Keishoku Sakuraba, Keisuke Sawaki
BACKGROUND: The major types of commercially available gelatin hydrolysates are prepared from mammals or fish. Dietary gelatin hydrolysates from mammals were reported to improve bone mineral density (BMD) in some animal models. In contrast, there is limited study showing the effects of dietary gelatin hydrolysates from fish on BMD. The quantity and structure of peptides in the plasma after oral administration of gelatin hydrolysates depend on the gelatin source, which suggests that the biological activity of gelatin hydrolysates depend on the gelatin source...
September 5, 2017: BMC Musculoskeletal Disorders
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