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Magnesium deficiency

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https://www.readbyqxmd.com/read/27925712/quantitative-assessment-of-nutrition-in-patients-with-polycystic-ovary-syndrome-pcos
#1
Małgorzata Szczuko, Magdalena Skowronek, Marta Zapałowska-Chwyć, Andrzej Starczewski
Background: PCOS (polycystic ovary syndrome) is called a pathology of the XX century and affects at least 10-15% women of childbearing age. The therapy involves pharmacotherapy of hormonal imbalance, as well as the change of lifestyle, including the diet. Objective: Performing the quantitative assessment of components of diets of women with PCOS, comparing the results with current dietary standards for Polish people and defining dietary requirements for the patients...
2016: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/27919433/sodc-modulates-ras-and-pkb-signaling-in-dictyostelium
#2
Boris Castillo, Seon-Hee Kim, Mujataba Sharief, Tong Sun, Lou W Kim
We have previously reported that the basal RasG activity is aberrantly high in cells lacking Superoxide dismutase C (SodC). Here we report that other Ras proteins such as RasC and RasD activities are not affected in sodC(-) cells and mutagenesis studies showed that the presence of the Cys(118) in the Ras proteins is essential for the superoxide-mediated activation of Ras proteins in Dictyostelium. In addition to the loss of SodC, lack of extracellular magnesium ions increased the level of intracellular superoxide and active RasG proteins...
November 30, 2016: European Journal of Cell Biology
https://www.readbyqxmd.com/read/27910808/magnesium-and-depression
#3
Anna Serefko, Aleksandra Szopa, Ewa Poleszak
Magnesium is one of the most important elements in the human body and is involved in a number of biochemical processes crucial for the proper functioning of the cardiovascular, alimentary, endocrine, and osteoarticular systems. It also plays a vital modulatory role in brain biochemistry, influencing several neurotransmission pathways associated with the development of depression. Personality changes, including apathy, depression, agitation, confusion, anxiety, and delirium are observed when there is a deficiency of this element...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27908421/low-magnesium-diet-alters-distribution-of-macroelements-and-trace-elements-in-tissues-and-organs-of-female-rats
#4
Anastasia A Zheltova, Maria V Kharitonova, Igor N Iezhitsa, Eugeny P Serebryansky, Oleg Y Evsyukov, Alexander A Spasov, Anatoly V Skalny
The aim of the present study was to assess whether dietary magnesium deficiency can alter distribution of macroelements and trace elements in different organs and tissues. Experiments were carried out on 12 adult female Wistar rats, which were fed either a diet with low Mg content (≤20mgkg(-1) of diet) (LMgD) or a diet with daily recommended Mg content (≈500mgkg(-1)) as control group (CG) for 70 days. On the 70th day of the experiment heart, aorta, femoral skeletal muscle, forebrain, cerebellum, pituitary gland, thyroid gland, ovaries, uterus, liver, kidneys, and spleen were taken for analysis of mineral content...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27900407/do-inhibitors-of-crystallisation-play-any-role-in-the-prevention-of-kidney-stones-a-critique
#5
REVIEW
William G Robertson
A critical examination of data in the literature and in as yet unpublished laboratory records on the possible role of so-called inhibitors of crystallisation in preventing the formation of calcium-containing kidney stones leads to the following conclusions. So-called inhibitors of spontaneous "self-nucleation" are unlikely to play any role in the initiation of the crystallisation of CaOx or CaP in urine because excessive urinary supersaturation of urine with respect to these salts dominates the onset of "self-nucleation" within the normal time frame of the transit of tubular fluid through the nephron (3-4 min)...
November 29, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27893657/status-of-serum-magnesium-in-egyptian-children-with-type-1-diabetes-and-its-correlation-to-glycemic-control-and-lipid-profile
#6
Doaa Shahbah, Amr Abo El Naga, Tamer Hassan, Marwa Zakaria, Mohamed Beshir, Salah Al Morshedy, Mohamed Abdalhady, Ezzat Kamel, Doaa Abdel Rahman, Lamiaa Kamel, May Abdelkader
Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency, having 25% to 39% prevalence. This deficit could be associated with the development of late diabetic complications, especially macroangiopathy.We aimed to evaluate the status of serum Mg in children with type 1 diabetes and assess its relation to glycemic control and lipid profile.We included 71 Egyptian children with type 1diabetes having their follow-up at Pediatric Endocrinology outpatient clinic, Zagazig University Hospital and 71 age- and sex-matched control...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27873163/an-update-on-the-use-of-immunomodulators-in-primary-immunodeficiencies
#7
REVIEW
Pandiarajan Vignesh, Amit Rawat, Surjit Singh
The genomic revolution in the past decade fuelled by breathtaking advances in sequencing technologies has defined several new genetic diseases of the immune system. Many of these newly characterized diseases are a result of defects in genes involved in immune regulation. The discovery of these diseases has opened a vista of new therapeutic possibilities. Immunomodulatory agents, a hitherto unexplored therapeutic option in primary immunodeficiency diseases have been tried in a host of these newly described maladies...
November 21, 2016: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/27866273/omeprazole-suppressed-plasma-magnesium-level-and-duodenal-magnesium-absorption-in-male-sprague-dawley-rats
#8
Narongrit Thongon, Jirawat Penguy, Sasikan Kulwong, Kanyanat Khongmueang, Matthana Thongma
Hypomagnesemia is the most concerned side effect of proton pump inhibitors (PPIs) in chronic users. However, the mechanism of PPIs-induced systemic Mg(2+) deficit is currently unclear. The present study aimed to elucidate the direct effect of short-term and long-term PPIs administrations on whole body Mg(2+) homeostasis and duodenal Mg(2+) absorption in rats. Mg(2+) homeostasis was studied by determining the serum Mg(2+) level, urine and fecal Mg(2+) excretions, and bone and muscle Mg(2+) contents. Duodenal Mg(2+) absorption as well as paracellular charge selectivity were studied...
November 2016: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27854048/magnesium-deficiency-and-oxidative-stress-an-update
#9
Anastasia A Zheltova, Maria V Kharitonova, Igor N Iezhitsa, Alexander A Spasov
Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidative modification products. Additionally, a relationship was detected between MgD and a weakened antioxidant defence. Different mechanisms associated with MgD are involved in the development and maintenance of OS...
December 2016: BioMedicine
https://www.readbyqxmd.com/read/27837349/comparison-of-body-composition-and-nutrients-deficiencies-between-portuguese-rink-hockey-players
#10
Maria-Raquel G Silva, Hugo-Henrique Silva
: We evaluated dietary intake and body composition of child and adolescent rink-hockey players and controls. Seventy-two male rink-hockey players (38 children and 34 adolescents) and 79 male controls (43 children and 36 adolescents) were evaluated in order to collect training data, detailed dietary intake and body composition. Rink-hockey players presented significantly lower body fat (BF) and higher fat-free mass (FFM) than controls. Mean intakes of carbohydrate and protein were considered to be adequate, but mean intakes of fat were above the recommended levels in athletes...
November 12, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27825399/fluctuations-in-metabolite-content-in-the-liver-of-magnesium-deficient-rats
#11
Mei Shigematsu, Ryosuke Nakagawa, Shozo Tomonaga, Masayuki Funaba, Tohru Matsui
Mg deficiency induces various metabolic disturbances including glucose metabolism in the liver. However, no comprehensive information is currently available on the metabolic pathways affected by Mg deficiency. The present study examined metabolite content in the liver of Mg-deficient rats using a metabolomic analysis. In this study, 4-week-old, male Sprague-Dawley rats were fed a control diet or a Mg-deficient diet for 8 weeks. The metabolomic analysis identified 105 metabolites in the liver, and significant differences were observed in the hepatic contents for thirty-three metabolites between the two groups...
November 9, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27818797/serum-magnesium-and-vitamin-d-levels-as-indicators-of-asthma-severity
#12
Mohammed Nadeem Shaikh, Brahma Reddy Malapati, Ruchi Gokani, Bhavita Patel, Mitul Chatriwala
Background. Serum magnesium levels affect the concentration of circulating vitamin D in blood and subsequently it affects the immunity; thus it plays significant role in the pathogenesis of asthma. Asthma, in adults, is less studied and hypomagnesemia along with vitamin D deficiency and insufficiency is common in asthmatic individuals, which causes frequent asthma attacks, respiratory infections, severe exacerbations, and poor response to bronchodilators. Objective. To detect the magnitude of vitamin D insufficiency and deficiency and serum magnesium levels among asthmatic patients and to correlate them with the severity of asthma...
2016: Pulmonary Medicine
https://www.readbyqxmd.com/read/27799013/ecotoxicological-assessment-of-dewatered-drinking-water-treatment-residue-for-environmental-recycling
#13
Nannan Yuan, Changhui Wang, Laura A Wendling, Yuansheng Pei
Drinking water treatment residue (DWTR) is commonly regarded as a waste product of drinking water treatment plant, which is disposed to sewer or to landfill, with associated financial and environmental costs. Fortunately, the beneficial recycle of DWTR in environmental remediation has been demonstrated in many reports. However, the lack of information concerning the potential toxicity of dewatered DWTR hinders its widespread use in environmental applications. The present study examined the ecotoxicity of dewatered aluminum (Al) and iron (Fe) DWTR leachates to a green alga, Chlorella vulgaris, systematically...
October 31, 2016: Environmental Technology
https://www.readbyqxmd.com/read/27785828/rapid-sodium-signaling-couples-glutamate-uptake-to-breakdown-of-atp-in-perivascular-astrocyte-endfeet
#14
Julia Langer, Niklas J Gerkau, Amin Derouiche, Christian Kleinhans, Behrouz Moshrefi-Ravasdjani, Michaela Fredrich, Karl W Kafitz, Gerald Seifert, Christian Steinhäuser, Christine R Rose
Perivascular endfeet of astrocytes are highly polarized compartments that ensheath blood vessels and contribute to the blood-brain barrier. They experience calcium transients with neuronal activity, a phenomenon involved in neurovascular coupling. Endfeet also mediate the uptake of glucose from the blood, a process stimulated in active brain regions. Here, we demonstrate in mouse hippocampal tissue slices that endfeet undergo sodium signaling upon stimulation of glutamatergic synaptic activity. Glutamate-induced endfeet sodium transients were diminished by TFB-TBOA, suggesting that they were generated by sodium-dependent glutamate uptake...
October 27, 2016: Glia
https://www.readbyqxmd.com/read/27778151/data-from-controlled-metabolic-ward-studies-provide-guidance-for-the-determination-of-status-indicators-and-dietary-requirements-for-magnesium
#15
Forrest H Nielsen, Lu Ann K Johnson
Determination of whether magnesium (Mg) is a nutrient of public health concern has been hindered by questionable Dietary Recommended Intakes (DRIs) and problematic status indicators that make Mg deficiency assessment formidable. Balance data obtained since 1997 indicate that the EAR and RDA for 70-kg healthy individuals are about 175 and 250 mg/day, respectively, and these DRIs decrease or increase based on body weight. These DRIs are less than those established for the USA and Canada. Urinary excretion data from tightly controlled metabolic unit balance studies indicate that urinary Mg excretion is 40 to 80 mg (1...
October 24, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27775153/ethylene-and-nitric-oxide-interact-to-regulate-the-magnesium-deficiency-induced-root-hair-development-in-arabidopsis
#16
Miao Liu, Xing Xing Liu, Xiao Lin He, Li Juan Liu, Hao Wu, Cai Xian Tang, Yong Song Zhang, Chong Wei Jin
Nitric oxide (NO) and ethylene respond to biotic and abiotic stresses through either similar or independent processes. This study examines the mechanism underlying the effects of NO and ethylene on promoting root hair development in Arabidopsis under magnesium (Mg) deficiency. The interaction between NO and ethylene in the regulation of Mg deficiency-induced root hair development was investigated using NO- and ethylene-related mutants and pharmacological methods. Mg deficiency triggered a burst of NO and ethylene, accompanied by a stimulated development of root hairs...
October 24, 2016: New Phytologist
https://www.readbyqxmd.com/read/27733860/association-of-increased-grain-iron-and-zinc-concentrations-with-agro-morphological-traits-of-biofortified-rice
#17
Laura T Moreno-Moyano, Julien P Bonneau, José T Sánchez-Palacios, Joseph Tohme, Alexander A T Johnson
Biofortification of rice (Oryza sativa L.) with micronutrients is widely recognized as a sustainable strategy to alleviate human iron (Fe) and zinc (Zn) deficiencies in developing countries where rice is the staple food. Constitutive overexpression of the rice nicotianamine synthase (OsNAS) genes has been successfully implemented to increase Fe and Zn concentrations in unpolished and polished rice grain. Intensive research is now needed to couple this high-micronutrient trait with high grain yields. We investigated associations of increased grain Fe and Zn concentrations with agro-morphological traits of backcross twice second filial (BC2F2) transgenic progeny carrying OsNAS1 or OsNAS2 overexpression constructs under indica/japonica and japonica/japonica genetic backgrounds...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27727100/the-dietary-quality-of-food-pantry-users-a%C3%A2-systematic-review-of-existing-literature
#18
Anja Simmet, Julia Depa, Peter Tinnemann, Nanette Stroebele-Benschop
Users of food pantries often have a long history of food insecurity and may be vulnerable to nutritional deficiencies. The quality of their diets is not well researched. The purpose of this systematic review was to summarize the published evidence about the dietary quality of food pantry users. Systematic database searches of PubMed, PsycINFO, PsycARTICLES, and Psychology Behavioral Sciences Collection, and hand searches of references were conducted to identify cross-sectional, cohort, and intervention studies reporting baseline data, conducted in high-income countries and published between 1980 and 2015, which reported on the nutritional adequacy of individuals who have used a food pantry at least once in the previous 12 months...
October 7, 2016: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27721223/lifestyle-modifications-to-prevent-and-control-hypertension
#19
Fariba Samadian, Nooshin Dalili, Ali Jamalian
Hypertension is the most important, modifiable risk factor for cardiovascular disease and mortality. High salt intake may predispose children to develop hypertension later. A modest reduction in population salt intake worldwide would result in a major improvement in public health. Regarding smoking as another risk factor, there are various strategies that can be used to promote smoking cessation. Physicians are in an excellent position to help their patients stop smoking. Targeted weight loss interventions in population subgroups might be more effective for the prevention of hypertension than a general-population approach...
September 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27716044/identification-and-expression-analysis-of-oslpr-family-revealed-the-potential-roles-of-oslpr3-and-5-in-maintaining-phosphate-homeostasis-in-rice
#20
Yue Cao, Hao Ai, Ajay Jain, Xueneng Wu, Liang Zhang, Wenxia Pei, Aiqun Chen, Guohua Xu, Shubin Sun
BACKGROUND: Phosphorus (P), an essential macronutrient, is often limiting in soils and affects plant growth and development. In Arabidopsis thaliana, Low Phosphate Root1 (LPR1) and its close paralog LPR2 encode multicopper oxidases (MCOs). They regulate meristem responses of root system to phosphate (Pi) deficiency. However, the roles of LPR gene family in rice (Oryza sativa) in maintaining Pi homeostasis have not been elucidated as yet. RESULTS: Here, the identification and expression analysis for the homologs of LPR1/2 in rice were carried out...
October 3, 2016: BMC Plant Biology
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