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https://www.readbyqxmd.com/read/29778549/linked-color-imaging-can-help-gastric-helicobacter-pylori-infection-diagnosis-during-endoscopy
#1
Tsung-Hsing Chen, Chen-Ming Hsu, Hao-Tsai Cheng, Yin-Yi Chu, Ming-Yao Su, Jun-Te Hsu, Ta-Sen Yeh, Chang-Fu Kuo, Cheng-Tang Chiu
BACKGROUND: Esophagogastroduodenoscopy (EGD) is a standard tool for detection of mucosal and submucosal lesions. However, identification of Helicobacter pylori (H. P) infection using EGD alone is limited in accuracy. Linked color imaging (LCI) is a novel tool to capture real-time image with sufficient contrast to observe mucosal microstructure. METHODS: This study aims to evaluate the applicability of LCI in the identification of H. pylori infection. Consecutive 122 patients scheduled for EGD were included...
May 16, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29775994/a-broader-understanding-of-care-managers-attitudes-of-advance-care-planning-a-concurrent-nested-design
#2
Julie Aultman, Kristin R Baughman, Ruth Ludwick
AIMS AND OBJECTIVES: To examine barriers of advance care planning (ACP) experienced by care managers (CMs) through a mixed methods approach. A concurrent nested design was used to acquire a deeper understanding of ACP, and to identify nuances between quantitative and qualitative data. BACKGROUND: Past quantitative studies on providers have identified barriers related to time, culture, knowledge, responsibility, and availability of legal documents. These barriers, and accompanying attitudes and feelings, have been taken at face value without rich qualitative data to identify under what conditions and to what extent a barrier impacts care...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775512/improving-post-hospital-medication-management-in-a-danish-municipality-a-process-evaluation
#3
Mette Geil Kollerup, Tine Curtis, Birgitte Schantz Laursen
AIMS AND OBJECTIVES: This study evaluates an intervention developed to improve patient safety in post-hospital medication management carried out by visiting nurses working in a municipality in Denmark. The intervention consisted of three elements: an initial inter-disciplinary home visit by nurses, two subsequent scheduled visits, and the use of an organising tool. BACKGROUND: As a consequence of specialised treatment plans and new treatment possibilities, patients with complex care needs can now be discharged from hospital more rapidly - and in greater numbers - than previously...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775509/exploring-the-growth-trajectory-of-cultural-competence-in-taiwanese-paediatric-nurses
#4
Chiu-I Chen, Mei-Chih Huang
AIM: The purpose of this study was to explore the evolution of cultural competence in Taiwanese paediatric nurses. BACKGROUND: Because transnational marriage has become a social phenomenon in Taiwan, the proportion of newborns of new immigrant mothers accounts for 8-10% of total births every year. Since family-centered care is the core value of paediatric nursing, it is necessary to teach caregivers how to take care of hospitalized children and perform related nursing care as well as to determine what difficulties nurses will encounter when they care for patients from diverse cultures and to find solutions for these problems...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775227/choosing-to-decline-finding-common-ground-through-the-perspective-of-shared-decision-making
#5
Michele Megregian, Marianne Nieuwenhuijze
Respectful communication is a key component of any clinical relationship. Shared decision making is the process of collaboration that occurs between a health care provider and patient in order to make health care decisions based upon the best available evidence and the individual's preferences. A midwife and woman (and her support persons) engage together to make health care decisions, using respectful communication that is based upon the best available evidence and the woman's preferences, values, and goals...
May 18, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29774180/survival-prediction-based-on-qualitative-mri-diffusion-signature-in-patients-with-recurrent-high-grade-glioma-treated-with-bevacizumab
#6
Pradeep Goyal, Mary Tenenbaum, Sonali Gupta, Puneet S Kochar, Alok A Bhatt, Manisha Mangla, Yogesh Kumar, Rajiv Mangla
Background: Bevacizumab was approved by the FDA for the treatment of recurrent or progressive glioblastoma (GBM). Imaging responses are typically assessed by gadolinium-enhanced MRI. We sought to determine the significance of qualitative diffusion signature (manifest as variable degree of dark signal) on ADC maps in recurrent gliomas after treatment with bevacizumab. Methods: We performed an institutional review board (IRB) approved retrospective study on patients who underwent MRI of the brain after 8 weeks of receiving bevacizumab for recurrent glioma...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29773640/health-care-utilization-and-burden-of-diabetic-ketoacidosis-in-the-u-s-over-the-past-decade-a-nationwide-analysis
#7
Dimpi Desai, Dhruv Mehta, Priyanka Mathias, Gopal Menon, Ulrich K Schubart
OBJECTIVE: Diabetes is one of the most common chronic diseases and a leading cause of morbidity and mortality in the U.S. Although our ability to treat diabetes and its associated complications has significantly improved, presentation with uncontrolled diabetes leading to ketoacidosis remains a significant problem. RESEARCH DESIGN AND METHODS: We aimed to determine the incidence and costs of hospital admissions associated with diabetic ketoacidosis (DKA). We reviewed the National Inpatient Sample Database for all hospitalizations in which DKA (ICD-9 codes 250...
May 17, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29772886/urban-environmental-clustering-to-assess-the-spatial-dynamics-of-aedes-aegypti-breeding-sites
#8
Guillermo Albrieu-Llinás, Manuel O Espinosa, Agustín Quaglia, Marcelo Abril, Carlos Marcelo Scavuzzo
The identification of Aedes aegypti breeding hotspots in urban areas is crucial for the rational design of control strategies against this disease vector. Remote sensing and geographic information systems offer valuable tools for mapping habitat suitability of a given area. However, predicting species occurrences by means of probability distribution maps based on transversal entomological surveys has limited utility for local authorities. The aim of the present study was to carefully examine the temporal evolution of the number of houses infested with immature stages of Ae...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29771764/intestinal-fatty-acid-binding-protein-as-a-marker-of-necrosis-and-severity-in-acute-pancreatitis
#9
Juozas Kupčinskas, Rolandas Gedgaudas, Hannes Hartman, Tomi Sippola, Outi Lindström, Colin Johnson, Sara Regnér
OBJECTIVES: The aim of this study was to study intestinal fatty acid binding protein (i-FABP) as a potential biomarker in predicting severity of acute pancreatitis (AP). METHODS: In a prospective multicenter cohort study plasma levels of i-FABP were measured in 402 patients with AP. Severity of AP was determined based on the 1992 Atlanta Classification. RESULTS: Admission levels of plasma i-FABP were significantly higher in patients with pancreatic necrosis, in patients having systemic complications, in patients treated invasively, in patients treated in the intensive care unit, in patients with severe AP, and in deceased patients...
May 17, 2018: Pancreas
https://www.readbyqxmd.com/read/29771570/how-primary-health-care-staff-working-in-rural-and-remote-areas-access-skill-development-and-expertise-to-support-health-promotion-practice
#10
Kathryn A McFarlane, Jenni Judd, Hylda Wapau, Nina Nichols, Kerrianne Watt, Sue Devine
INTRODUCTION: Health promotion is a key component of comprehensive primary health care. Health promotion approaches complement healthcare management by enabling individuals to increase control over their health. Many primary healthcare staff have a role to play in health promotion practice, but their ability to integrate health promotion into practice is influenced by their previous training and experience. For primary healthcare staff working in rural and remote locations, access to professional development can be limited by what is locally available and prohibitive in terms of cost for travel and accommodation...
May 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/29771225/the-resident-physician-as-leader-within-the-healthcare-team
#11
Lyn Kathryn Sonnenberg, Lesley Pritchard-Wiart, Jamiu Busari
Purpose The purpose of this study was to explore inter-professional clinicians' perspectives on resident leadership in the context of inter-professional teams and to identify a definition for leadership in the clinical context. In 2015, CanMEDS changed the title of one of the core competencies from manager to leader. The shift in language was perceived by some as returning to traditional hierarchical and physician-dominant structures. The resulting uncertainty has resulted in a call to action to not only determine what physician leadership is but to also determine how to teach and assess it...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29771223/enabling-physicians-to-lead-canada-s-leads-framework
#12
Graham Dickson, John Van Aerde
Purpose The purpose of this paper is to provide a case study demonstrating that LEADS in a Caring Environment Capabilities Framework in Canada can assist physicians to be partners in leading health reform. Design/methodology/approach A descriptive case-based approach was followed, relying on existing documents, research papers and peer-reviewed articles, to substantiate the effect of LEADS on physician leadership in Canada. Findings The Canadian LEADS framework enables physicians to lead by providing them with access to best practices of leadership, acting as an antidote to fragmented leadership practice, setting standards for development and accountability and providing opportunities for efficient and effective system-wide leadership development and change...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29771210/variables-affecting-hospital-length-of-stay-a-scoping-review
#13
Sandra C Buttigieg, Lorraine Abela, Adriana Pace
Purpose Tertiary hospitals have registered an incremental rise in expenditure mostly because of the increasing demands by ageing populations. Reducing the length of stay (LOS) of patients within tertiary hospitals is one of the strategies, which has been used in the last decades to ensure health care systems' sustainability. Furthermore, LOS is one of the key performance indicators, which is widely used to assess hospital efficiency. Hence, it is crucial that policy makers use evidence-based practices in health care to aim for optimal LOS...
May 21, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29771205/organizational-health-management-through-metaphor-a-mission-based-approach
#14
Joseph M Woodside
Purpose The purpose of this paper is to identify the underlying metaphors that hospitals use to establish their organizational mission. Metaphors impact the direction and managerial decision making of organizations, and provide a method to more easily communicate to a variety of stakeholders. Design/methodology/approach A text analytics process is run to evaluate the mission statements from the largest hospitals by revenue in each of the 50 states of the USA and District of Columbia to identify the types of metaphor-based organizational health management methods...
May 21, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29769275/-point-counterpoint-active-surveillance-for-carriers-of-toxigenic-clostridium-difficile-should-be-performed-to-guide-prevention-efforts
#15
L Clifford McDonald, Daniel J Diekema
In 2017, we published a point-counterpoint on laboratory diagnosis of C. difficile infection (CDI). At that time, Drs Ferric Fang, Christopher Polage, and Mark Wilcox discussed the strategies for diagnosing Clostridium difficile colitis in symptomatic patients. Since that manuscript new guidelines from the Infectious Diseases Society of American and the Society for Health Care Epidemiology have been published (1) and healthcare systems have begun to explore screening asymptomatic patients for C. difficile colonization...
May 16, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29769103/the-alfa-and-beta-of-tumours-a-review-of-parameters-of-the-linear-quadratic-model-derived-from-clinical-radiotherapy-studies
#16
REVIEW
C M van Leeuwen, A L Oei, J Crezee, A Bel, N A P Franken, L J A Stalpers, H P Kok
BACKGROUND: Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the LQ model is mainly used to estimate equivalent radiotherapy schedules (e.g. calculate the equivalent dose in 2 Gy fractions, EQD2 ), but increasingly also to predict tumour control probability (TCP) and normal tissue complication probability (NTCP) using logistic models...
May 16, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29768712/innovation-at-the-intersection-of-clinical-trials-and-real-world-data-science-to-advance-patient-care
#17
REVIEW
Brandon Swift, Lokesh Jain, Craig White, Vasu Chandrasekaran, Aman Bhandari, Dyfrig A Hughes, Pravin R Jadhav
While efficacy and safety data collected from randomized clinical trials are the evidentiary standard for determining market authorization, this alone may no longer be sufficient to address the needs of key stakeholders (regulators, providers, and payers) and guarantee long-term success of pharmaceutical products. There is a heightened interest from stakeholders on understanding the use of real-world evidence (RWE) to substantiate benefit-risk assessment and support the value of a new drug. This review provides an overview of real-world data (RWD) and related advances in the regulatory framework, and discusses their impact on clinical research and development...
May 16, 2018: Clinical and Translational Science
https://www.readbyqxmd.com/read/29768500/clinically-relevant-inflammatory-breast-cancer-patient-derived-xenograft-derived-ex-vivo-model-for-evaluation-of-tumor-specific-therapies
#18
Bedrich L Eckhardt, Maria Gagliardi, LaKesla Iles, Kurt Evans, Cristina Ivan, Xiuping Liu, Chang-Gong Liu, Glauco Souza, Arvind Rao, Funda Meric-Bernstam, Naoto T Ueno, Geoffrey A Bartholomeusz
Inflammatory breast cancer (IBC) is a rare and aggressive presentation of invasive breast cancer with a 62% to 68% 5-year survival rate. It is the most lethal form of breast cancer, and early recognition and treatment is important for patient survival. Like non-inflammatory breast cancer, IBC comprises multiple subtypes, with the triple-negative subtype being overrepresented. Although the current multimodality treatment regime of anthracycline- and taxane-based neoadjuvant therapy, surgery, and radiotherapy has improved the outcome of patients with triple-negative IBC, overall survival continues to be worse than in patients with non-inflammatory locally advanced breast cancer...
2018: PloS One
https://www.readbyqxmd.com/read/29768430/a-qualitative-study-of-implementation-and-adaptations-to-progressive-tinnitus-management-ptm-delivery
#19
Anaïs Tuepker, Christine Elnitsky, Summer Newell, Tara Zaugg, James A Henry
BACKGROUND: Tinnitus is a common condition, especially prevalent among military Veterans. Progressive Tinnitus Management (PTM) is an interdisciplinary, structured, stepped-care approach to providing clinical services, including teaching coping skills, to people bothered by tinnitus. PTM has been shown to be effective at reducing functional distress, but implementation of the intervention outside of a research setting has not been studied, even though dissemination is underway within the Veterans Health Administration (VHA) system in the United States...
2018: PloS One
https://www.readbyqxmd.com/read/29767675/a-comparison-of-methods-for-adjusting-biomarkers-of-iron-zinc-and-selenium-status-for-the-effect-of-inflammation-in-an-older-population-a-case-for-interleukin-6
#20
Sue O MacDonell, Jody C Miller, Michelle J Harper, Malcolm R Reid, Jillian J Haszard, Rosalind S Gibson, Lisa A Houghton
Background: Older people are at risk of micronutrient deficiencies, which can be under- or overestimated in the presence of inflammation. Several methods have been proposed to adjust for the effect of inflammation; however, to our knowledge, none have been investigated in older adults in whom chronic inflammation is common. Objective: We investigated the influence of various inflammation-adjustment methods on micronutrient biomarkers associated with anemia in older people living in aged-care facilities in New Zealand...
May 14, 2018: American Journal of Clinical Nutrition
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