keyword
https://read.qxmd.com/read/38493159/screening-for-lung-cancer-with-computed-tomography-protocol-for-systematic-reviews-for-the-canadian-task-force-on-preventive-health-care
#1
JOURNAL ARTICLE
Jennifer Pillay, Sholeh Rahman, Scott Klarenbach, Donna L Reynolds, Laure A Tessier, Guylène Thériault, Nav Persaud, Christian Finley, Natasha Leighl, Matthew D F McInnes, Chantelle Garritty, Gregory Traversy, Maria Tan, Lisa Hartling
PURPOSE: Lung cancer is the leading cause of cancer deaths in Canada, and because early cancers are often asymptomatic screening aims to prevent mortality by detecting cancer earlier when treatment is more likely to be curative. These reviews will inform updated recommendations by the Canadian Task Force on Preventive Health Care on screening for lung cancer. METHODS: We will update the review on the benefits and harms of screening with CT conducted for the task force in 2015 and perform de novo reviews on the comparative effects between (i) trial-based selection criteria and use of risk prediction models and (ii) trial-based nodule classification and different nodule classification systems and on patients' values and preferences...
March 16, 2024: Systematic Reviews
https://read.qxmd.com/read/38492945/healthcare-utilization-and-left-ventricular-ejection-fraction-distribution-in-methamphetamine-use-associated-heart-failure-hospitalizations
#2
JOURNAL ARTICLE
Veena Manja, Alexander Tarlochan Singh Sandhu, Steven Asch, Susan Frayne, Mark McGovern, Cheng Chen, Paul Heidenreich
BACKGROUND: Although methamphetamine use associated heart failure (MU-HF) is increasing, data on its clinical course are limited due to a preponderance of single center studies and significant heterogeneity in the definition of MU-HF in the published literature. Our objective was to evaluate left ventricular ejection fraction (LVEF) distribution, methamphetamine use treatment engagement and postdischarge healthcare utilization among Veterans with heart failure hospitalization in the department of Veterans Affairs (VA) medical centers for MU-HF versus HF not associated with methamphetamine use (other-HF)...
April 2024: American Heart Journal
https://read.qxmd.com/read/38492926/psychometric-properties-of-general-oral-health-assessment-index-across-ages-cosmin-systematic-review
#3
REVIEW
Judit Oszlánszky, László Gulácsi, Márta Péntek, Péter Hermann, Zsombor Zrubka
OBJECTIVES: To systematically review the psychometric properties of the Geriatric Oral Health Assessment Index (GOHAI) across age groups using the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) methodology. METHODS: Data: English peer-reviewed articles reporting studies of the development, translation, or validation of GOHAI. SOURCES: PubMed, Web of Science and EMBASE from Jan 1990 until 31. December 2023...
March 14, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38492925/comparison-of-eq-health-and-well-being-long-and-short-eq-hwb-eq-hwb-s-with-other-preference-based-measures-among-united-states-informal-caregivers
#4
JOURNAL ARTICLE
Maja Kuharic, Brendan Mulhern, Lisa K Sharp, Robin S Turpin, A Simon Pickard
OBJECTIVE: Several measures have been used or developed to capture the health and well-being of caregivers, including the EQ Health and Well-being (EQ-HWB) and its short form, EQ-HWB-S. This study aimed to evaluate the psychometric properties and construct validity of the EQ-HWB/EQ-HWB-S in a US caregiver population. METHODS: A cross-sectional survey was conducted involving 504 caregivers. Eligible participants were 18+ years old, provided unpaid care to a relative/friend aged 18+ in the past six months, and spent on average of at least one hour per week caregiving...
March 14, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38492924/cost-effectiveness-of-two-models-of-pessary-care-for-pelvic-organ-prolapse-findings-from-the-topsy-randomised-controlled-trial
#5
JOURNAL ARTICLE
Sarkis Manoukian, Helen Mason, Suzanne Hagen, Rohna Kearney, Kirsteen Goodman, Catherine Best, Andrew Elders, Lynn Melone, Lucy Dwyer, Melanie Dembinsky, Aethele Khunda, Karen Lesley Guerrero, Doreen McClurg, John Norrie, Ranee Thakar, Carol Bugge
OBJECTIVES: Pelvic organ prolapse is the descent of one or more reproductive organs from their normal position, causing associated negative symptoms. One conservative treatment option is pessary management. The aim of this study was to investigate the cost-effectiveness of pessary self-management (SM) when compared to clinic-based care (CBC). A decision-analytic model was developed to extend the economic evaluation. METHODS: A randomised controlled trial with health economic evaluation...
March 14, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38492098/impact-of-reimbursement-systems-on-patient-care-a-systematic-review-of-systematic-reviews
#6
REVIEW
Eva Wagenschieber, Dominik Blunck
BACKGROUND: There is not yet sufficient scientific evidence to answer the question of the extent to which different reimbursement systems influence patient care and treatment quality. Due to the asymmetry of information between physicians, health insurers and patients, market-based mechanisms are necessary to ensure the best possible patient care. The aim of this study is to investigate how reimbursement systems influence multiple areas of patient care in form of structure, process and outcome indicators...
March 16, 2024: Health Economics Review
https://read.qxmd.com/read/38491962/quantifying-preferences-for-urea-cycle-disorder-treatments-using-a-discrete-choice-experiment
#7
JOURNAL ARTICLE
Josiah Edelblut, Jeffrey R Skaar, John Hilton, Matthew Seibt, Kyle Martin, Nandini Hadker, Adrian Quartel, Robert D Steiner
Aims : Urea cycle disorders (UCDs) can cause ammonia accumulation and central nervous system toxicity. Nitrogen-binding medications can be efficacious but certain attributes may negatively impact adherence. This study sought to quantify the administration-related attributes influencing overall prescription selection and patient adherence. Methods: A web-based, quantitative survey including discrete choice experiment (DCE) methodology captured responses from health care providers for patients with UCDs. A series of hypothetical treatment profile sets with attributes such as route of administration, taste/odor, preparation instructions, packaging, dose measurement, and weight use restrictions were presented...
March 16, 2024: Journal of Medical Economics
https://read.qxmd.com/read/38491738/engaging-patients-in-designing-a-transmural-allied-health-pathway-a-qualitative-exploration-of-hospital-to-home-transitions
#8
JOURNAL ARTICLE
Juul W M van Grootel, Romain J Collet, Mel E Major, Suzanne Wiertsema, Hanneke van Dongen, Marike van der Leeden, Edwin Geleijn, Raymond Ostelo, Marike van der Schaaf
INTRODUCTION: The transition from hospital to home is often suboptimal, resulting in patients not receiving the necessary allied healthcare after discharge. This may, in turn, lead to delayed recovery, a higher number of readmissions, more emergency department visits and an increase in mortality and healthcare costs. This study aimed to gain insight into patients' experiences, perceptions, and needs regarding hospital-to-home transition, focusing on allied healthcare as a first step towards the development of a transitional integrated allied healthcare pathway for patients with complex care needs after hospital discharge...
April 2024: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/38491476/cultivating-compassion-in-medicine-a-toolkit-for-medical-students-to-improve-self-kindness-and-enhance-clinical-care
#9
JOURNAL ARTICLE
Krisha K Mehta, Shafkat Salam, Austin Hake, Rebecca Jennings, Afra Rahman, Stephen G Post
BACKGROUND: Compassionate care lies at the foundation of good patient care and is a quality that patients and providers continue to value in the fast-paced setting of contemporary medicine. Compassion is often discussed superficially in medical school curricula, but the practical aspect of learning this skill is often not taught using a formal framework. In the present work, the authors present an 8-session curriculum with a mindfulness-based approach to compassion that addresses this need...
March 15, 2024: BMC Medical Education
https://read.qxmd.com/read/38491464/long-term-patient-centered-frailty-based-outcomes-of-older-critical-illness-survivors-from-the-emergency-department-a-post-hoc-analysis-of-the-life-study
#10
JOURNAL ARTICLE
Takashi Hongo, Tetsuya Yumoto, Mototaka Inaba, Shunsuke Taito, Takashi Yorifuji, Atsunori Nakao, Hiromichi Naito
BACKGROUND: Evidence indicates frailty before intensive care unit (ICU) admission leads to poor outcomes. However, it is unclear whether quality of life (QOL) and activities of daily living (ADL) for survivors of critical illness admitted to the ICU via the emergency department remain consistent or deteriorate in the long-term compared to baseline. This study aimed to evaluate long-term QOL/ADL outcomes in these patients, categorized by the presence or absence of frailty according to Clinical Frailty Scale (CFS) score, as well as explore factors that influence these outcomes...
March 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38491374/can-the-reboot-coaching-programme-support-critical-care-nurses-in-coping-with-stressful-clinical-events-a-mixed-methods-evaluation-assessing-resilience-burnout-depression-and-turnover-intentions
#11
JOURNAL ARTICLE
K S Vogt, J Johnson, R Coleman, R Simms-Ellis, R Harrison, N Shearman, J Marran, L Budworth, C Horsfield, R Lawton, A Grange
BACKGROUND: Critical care nurses (CCNs) are routinely exposed to highly stressful situations, and at high-risk of suffering from work-related stress and developing burnout. Thus, supporting CCN wellbeing is crucial. One approach for delivering this support is by preparing CCNs for situations they may encounter, drawing on evidence-based techniques to strengthen psychological coping strategies. The current study tailored a Resilience-boosting psychological coaching programme [Reboot] to CCNs...
March 15, 2024: BMC Health Services Research
https://read.qxmd.com/read/38490779/inhaled-nitroglycerin-for-pulmonary-edema-in-air-medical-services-a-retrospective-pilot-study
#12
JOURNAL ARTICLE
Abigail Polzin, Eric D Curtis, Eric Rupe, Hilla I Sang
OBJECTIVE: The use of traditional inhaled pulmonary vasodilators, such as nitric oxide, to treat symptomatic pulmonary edema is not practical in the air medical or prehospital environment because of difficulty with administration. A hospital-based critical care air medical transport service initiated a pilot study to investigate the use of inhaled nitroglycerin (iNTG) as an alternative pulmonary vasodilator. METHODS: For this pilot study, iNTG was administered using a jet nebulizer setup and concentrated nitroglycerin, both of which are widely available in acute care settings...
2024: Air Medical Journal
https://read.qxmd.com/read/38490471/the-measurement-properties-of-the-eq-health-and-wellbeing-eq-hwb-and-eq-health-and-wellbeing-short-form-eq-hwb-s-in-italian-population-a-comparative-study-with-eq-5d-5l
#13
JOURNAL ARTICLE
Maja Kuharić, A Simon Pickard, Clara Mukuria, Aureliano Paolo Finch
OBJECTIVES: The EQ Health and Wellbeing, EQ-HWB (25-item) and the EQ-HWB-S (9-item), are new generic measures of health and wellbeing. The purpose of this study was to examine the measurement properties of the EQ-HWB and EQ-HWB-S measures in relation to the EQ-5D-5L among the Italian general population. METHODS: A cross-sectional survey was conducted from October 2020 to February 2021, followed by secondary analysis of collected data from Italian adults. This analysis included response pattern distributions, correlation strength, and known group comparison (KGC)...
March 13, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38490449/cardiovascular-magnetic-resonance-based-tissue-characterization-in-patients-with-hypertrophic-cardiomyopathy
#14
REVIEW
Atish Vanmali, Waleed Alhumaid, James A White
Hypertrophic cardiomyopathy (HCM) is a relatively common hereditable cardiomyopathy that affects between 1:200 to 1:500 of the general population. The role of cardiovascular magnetic resonance (CMR) imaging in the management of HCM has expanded over the past two decades to become a key informant of risk in this patient population, delivering unique insights into tissue health and its influence on future outcomes. Numerous mature CMR-based techniques are clinically available for the interrogation of tissue health in patients with HCM, inclusive of contrast and non-contrast methods...
March 13, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38490312/clinical-usefulness-of-a-host-signature-based-on-trail-ip10-and-crp-memed-bv-as-infection-biomarkers-in-intensive-care-units-patients-a-retrospective-observational-study
#15
JOURNAL ARTICLE
Karol P Steckiewicz, Magdalena A Wujtewicz, Michał Okrągły, Aleksander Aszkiełowicz, Malgorzata Dąbrowska, Radosław Owczuk
INTRODUCTION: Infection complications are common in intensive care unit patients, and early detection remains a diagnostic challenge. Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers. A novel diagnostic approach focuses on the host immune response. One of the novel approaches, the MMBV index, is based on measuring in a blood sample three parameters: (i) tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), (ii) interferon-γ-induced protein-10 (IP10), and (iii) CRP...
March 13, 2024: Clinical Biochemistry
https://read.qxmd.com/read/38490251/comparison-of-national-factor-based-models-for-preeclampsia-screening
#16
JOURNAL ARTICLE
Louise Ghesquière, Emmanuel Bujold, Eric Dubé, Nils Chaillet
OBJECTIVE:  This study aimed to compare the predictive values of the American College of Obstetricians and Gynecologists (ACOG), the National Institute for Health and Care Excellence (NICE), and the Society of Obstetricians and Gynecologists of Canada (SOGC) factor-based models for preeclampsia (PE) screening. STUDY DESIGN:  We conducted a secondary analysis of maternal and birth data from 32 hospitals. For each delivery, we calculated the risk of PE according to the ACOG, the NICE, and the SOGC models...
March 15, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38490217/diagnostic-potential-of-complementation-of-mri-to-prenatal-ultrasound-for-detecting-orofacial-clefts-in-high-risk-fetuses-a-network-meta-analysis
#17
JOURNAL ARTICLE
Jing Zhai, Shuyan You, Zhonghua Liang, Haihua Yu, Chengfeng Zhu, Lu Han
OBJECTIVE: To compare the complementation of magnetic resonance imaging (MRI) to prenatal ultrasound (US) with prenatal US alone in detecting orofacial clefts in high-risk fetuses. DESIGN: A network meta-analysis. SETTING: Literature retrieval in PubMed, EMBASE, and Cochrane library, and meta-analysis based on STATA 14.0. PATIENTS: Fetuses were at high-risk for orofacial clefts. INTERVENTIONS: Prenatal US and the complementation of MRI to prenatal US...
March 15, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38490090/evaluation-of-prognostic-scores-for-status-epilepticus-in-the-neurology-icu-a-retrospective-study
#18
JOURNAL ARTICLE
Jia Yi Shen, Seyed Ehsan Saffari, Linda Yong, Nigel Choon Kiat Tan, Yee-Leng Tan
OBJECTIVE: Status epilepticus (SE) in the neurology intensive care unit (ICU) is associated with significant morbidity. We aimed to evaluate the utility of existing prognostic scores, namely the Status Epilepticus Severity Score (STESS), Epidemiology Based Mortality Score in Status Epilepticus (EMSE)-EACE and Encephalitis-Nonconvulsive Status Epilepticus-Diazepam Resistance-Image Abnormalities-Tracheal Intubation (END-IT), among SE patients in the neurology ICU. METHODS: Neurology ICU patients with SE requiring continuous electroencephalography (cEEG) monitoring over a 10 year period were included...
March 11, 2024: Journal of the Neurological Sciences
https://read.qxmd.com/read/38489764/outcomes-of-pediatric-proximal-phalanx-base-fractures
#19
JOURNAL ARTICLE
John Schutz, Hannah Korrell, Nicole Look, Andy Lalka, Johanna Hild, Gabriela Cleary, Micah K Sinclair, Sarah E Sibbel
INTRODUCTION: Extra-articular juxtaphyseal fractures of the proximal phalanx are among the most common finger fractures in children. Immobilization of the digit for 3 to 4 weeks after reduction of the fracture is the current standard of care. The purpose of this retrospective study was to evaluate outcomes after intervention among pediatric proximal phalanx base fractures and establish radiographic criteria to guide management. METHODS: A multi-institutional retrospective review of skeletally immature patients treated for proximal phalanx juxtaphyseal fractures between 2002 and 2019 was conducted...
March 14, 2024: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/38489281/antibiotic-overuse-poor-antimicrobial-stewardship-and-low-specificity-of-syndromic-case-management-in-a-cross-section-of-men-with-urethral-discharge-syndrome-in-kampala-uganda
#20
JOURNAL ARTICLE
Matthew M Hamill, Annet Onzia, Rosalind M Parkes-Ratanshi, Peter Kyambadde, Emmanuel Mande, Vivian Nakate, Johan H Melendez, Ethan Gough, Yukari C Manabe
OBJECTIVE: High prevalence of sexually transmitted infections (STIs) combined with poor antimicrobial stewardship are drivers of STI antimicrobial resistance (AMR) especially in resource-limited settings where syndromic case management (SCM) is the norm. We characterized patterns of antibiotic use prior to clinic attendance and study enrollment in Ugandan men with urethral discharge syndrome (UDS), evaluated in-clinic prescribing, and the performance characteristics of SCM. METHODS: Participants were recruited from government clinics participating in an existing gonococcal surveillance program in Kampala, Uganda...
2024: PloS One
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