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https://www.readbyqxmd.com/read/28320035/srage-is-elevated-in-the-lungs-of-premature-infants-receiving-mechanical-ventilation
#1
Henry J Rozycki, Jennifer Bradley, Simon Karam
Background Soluble receptor for advanced glycation end-products (sRAGE), a soluble isoform of the RAGE receptor, is elevated in lungs from patients with acute conditions such as acute respiratory distress syndrome and bronchiolitis. This study investigated whether sRAGE is present in ventilated infants. Methods Tracheal aspirates from the first week or the fifth week of life were obtained from intubated very low birth weight subjects and analyzed by Western blot. Immunohistochemistry analysis for sRAGE was performed on paraffin-embedded lung autopsy slides from 19 other infants...
March 20, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28315889/patterns-of-growth-in-early-childhood-and-infectious-disease-and-nutritional-determinants
#2
Robert E Black
The physical growth of young children in low- and middle-income countries is reduced compared to international standards. The deviations in growth in both weight and height are greatest in the first 2 years of life and this has serious consequences for child mortality, development, adult stature, and health. The determinants of these patterns of growth faltering include intergenerational factors, such as maternal height, short birth interval, and conditions in pregnancy, including maternal underweight and anemia...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28304327/retinopathy-of-prematurity-in-indonesia-incidence-and-risk-factors
#3
J Edy Siswanto, P Jj Sauer
BACKGROUND: Retinopathy of prematurity (ROP) is a vaso-proliferative disease of the eye, which mainly affects preterm newborn infants with an incompletely vascularized retina. The incidence of ROP has increased in industrialized countries due to the increased survival of extremely low birth weight (ELBW) infants. ROP is also increasing in developing countries like Indonesia, where it is most likely due to the improved survival of ELBW infants. OBJECTIVE: To ascertain the incidence of ROP and possible risk factors associated with the development of ROP in preterm infants in Indonesia...
March 16, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28304321/calcium-chloride-in-neonatal-parenteral-nutrition-a-15-year-experience
#4
R K Huston, J W Kaempf, M Wang, L Wang, Gary L Grunkemeier, Howard S Cohen
OBJECTIVE: The objective of this study was to determine if outcomes at our neonatal intensive care units (NICUs) since we began using calcium chloride (CaCl2) as our preferred calcium additive in order to reduce aluminum (Al) exposure are within expected outcome ranges for NICUs in the U.S. where calcium gluconate in glass vials (CaGlu-Gl) has been the preferred additive. STUDY DESIGN: A retrospective study of very low birth weight infants born between January 1, 2000 and December 31, 2014...
March 16, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28304320/optimal-radiologic-position-of-an-umbilical-venous-catheter-tip-as-determined-by-echocardiography-in-very-low-birth-weight-newborns
#5
B C F Karber, J Nielsen, D Balsam, C Messina, D Davidson
OBJECTIVE: To compare chest X-ray with echocardiogram (ECHO) in the localization of an umbilical venous catheter (UVC) tip in very low birth weight infants (VLBW). Secondary objectives determined the association between techniques for tip placement by the vertebral body level on X-ray, as well as the length of the thoracic inferior vena cava-right atrial (TIVC-RA) junction by ECHO. STUDY DESIGN: Prospective, sequentially enrolled, masked, single regional perinatal center study...
March 16, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28301849/long-term-adverse-effects-of-early-growth-acceleration-or-catch-up-growth
#6
Atul Singhal
BACKGROUND: Whilst prevention of growth faltering has both short- and long-term health benefits, whether too fast or accelerated infant growth adversely affects later health outcomes is controversial and a major focus of research. SUMMARY: Many observational studies suggest that rapid weight gain in infancy (upward centile crossing) increases the long-term risk of obesity and non-communicable disease. This association has been seen in infants from low- and high-income countries, in infants born preterm or at term, and those born with normal or low birth weight for gestation...
March 17, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28300011/neonatal-fatty-acid-profiles-are-correlated-with-infant-growth-measures-at-6-months
#7
P F O'Tierney-Ginn, D Davina, M Gillingham, D J P Barker, C Morris, K L Thornburg
Rapid weight gain in infancy and low levels of n-3 long chain polyunsaturated fatty acids (LCPUFA) at birth are associated with increased adiposity later in life. The association between placental LCPUFA delivery and weight gain in infancy is poorly understood. We sought to determine the relationships between maternal phenotype, placental fatty acid transporter expression and offspring growth patterns over the first 6 months. Placental tissue and cord blood were collected at term delivery from women with uncomplicated pregnancies...
March 16, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28298861/retinopathy-of-prematurity-revisiting-incidence-and-risk-factors-from-oman-compared-to-other-countries
#8
Zenaida Soriano Reyes, Sharef Waadallah Al-Mulaabed, Flordeliz Bataclan, Cheryl Montemayor, Anuradha Ganesh, Sanaa Al-Zuhaibi, Huda Al-Waili, Fatma Al-Wahibi
PURPOSE: The purpose of this study is to determine the incidence of retinopathy of prematurity (ROP) and the maternal/neonatal risk factors at a tertiary care hospital in Oman, compared to other countries. PATIENTS AND METHODS: A retrospective analysis of premature neonates born with gestational age (GA) 24-32 weeks at Sultan Qaboos University Hospital, Oman, from January 2007 to December 2010. Maternal and neonatal in-hospital course was retrieved. The incidence of ROP was reported...
January 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28298173/effects-of-two-different-lipid-emulsions-on-morbidities-and-oxidant-stress-statuses-in-preterm-infants-an-observational-study
#9
Sezin Unal, Nihal Demirel, Sara Erol, Dilek Ulubas Isik, Ferit Kulali, Fatma Iyigun, Ahmet Yagmur Bas
OBJECTIVE: We examined the morbidities and oxidative stress statuses in preterms receiving either SMOFlipid or ClinOleic. STUDY DESIGN: This observational study was performed in Etlik Zubeyde Hanim Hospital, Turkey. Infants received SMOFlipid (5 months) or ClinOleic (7 months). Two hundred and twenty seven infants (SMOFlipid: 93, ClinOleic: 134) very low birth weighted infants were included. The oxidative stress status was evaluated in infants at low risk of oxidative stress by total antioxidant capacity (TAC) and total oxidant status (TOS) and oxidative stress index (OSI; TAC/TOS/100) at baseline, first week and third week...
March 15, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28295577/higher-growth-fat-and-fat-free-masses-correlate-with-larger-cerebellar-volumes-in-preterm-infants-at-term
#10
Giulia Paviotti, Angela De Cunto, Floriana Zennaro, Giulia Boz, Laura Travan, Gabriele Cont, Jenny Bua, Sergio Demarini
AIM: Smaller cerebellar volumes in very low birth weight (VLBW) infants at term have been related to adverse cognitive outcomes and this study evaluated whether these volumes were associated with a growth in body composition during hospital stays. METHODS: We prospectively recruited 42 VLBW infants from an Italian neonatal unit between January 2013 and August 2015. Cerebellar volumes and body composition were measured by magnetic resonance imaging (MRI) and air-displacement plethysmography, respectively, at 40 weeks of gestational age and anthropometric and nutritional data were collected...
March 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28294399/the-impact-of-italian-regionalisation-on-transporting-neonatal-patients-back-from-the-neonatal-intensive-care-unit-to-the-referring-level-two-unit
#11
Carlo Bellini, Luca A Ramenghi
Perinatal regionalisation networks aim to centralise highly skilled care for high-risk neonates and their mothers (1). This study examined how the regional policy in Liguria, Italy, had changed the management of very low birth weight preterm infants. We were particularly keen to look at the impact on back transports, namely transferring patients back to a Level II unit once they did not need to be in the neonatal intensive care unit (NICU) at the IRCCS Istituto Giannina Gaslini, Genoa, Italy. This article is protected by copyright...
March 10, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28292615/perinatal-outcomes-among-singletons-after-assisted-reproductive-technology-with-single-embryo-or-double-embryo-transfer-versus-no-assisted-reproductive-technology
#12
Angela S Martin, Jeani Chang, Yujia Zhang, Jennifer F Kawwass, Sheree L Boulet, Patricia McKane, Dana Bernson, Dmitry M Kissin, Denise J Jamieson
OBJECTIVE: To examine outcomes of singleton pregnancies conceived without assisted reproductive technology (non-ART) compared with singletons conceived with ART by elective single-embryo transfer (eSET), nonelective single-embryo transfer (non-eSET), and double-embryo transfer with the establishment of 1 (DET -1) or ≥2 (DET ≥2) early fetal heartbeats. DESIGN: Retrospective cohort using linked ART surveillance data and vital records from Florida, Massachusetts, Michigan, and Connecticut...
March 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28292543/the-impact-of-kangaroo-care-on-premature-infant-weight-gain
#13
REVIEW
Melvina Evereklian, Bobbie Posmontier
BACKGROUND: Preterm births occur among 11.4% of all live infant births. Without steady weight gain, premature infants may experience lengthy hospitalizations, neurodevelopmental deficits and hospital readmissions, which can increase the financial burden on the health care system and their families. The total U.S. health-related costs linked to preterm infant deliveries are estimated at $4.33 billion. Kangaroo care is a feasible practice that can improve preterm infant weight gain. However, this intervention is utilized less often throughout the U...
March 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28291053/safety-of-tenofovir-disoproxil-fumarate-based-antiretroviral-therapy-regimens-in-pregnancy-for-hiv-infected-women-and-their-infants-a-systematic-review-and-meta-analysis
#14
Jean B Nachega, Olalekan A Uthman, Lynne M Mofenson, Jean R Anderson, Steve Kanters, Francoise Renaud, Nathan Ford, Shaffiq Essajee, Meg C Doherty, Edward J Mills
BACKGROUND: There are limited data on adverse effects of tenofovir disoproxil fumarate (TDF)-based antiretroviral therapy (ART) on pregnant women and their infants. METHODS: We conducted a systematic review of studies published between January 1980 and January 2017 that compared adverse outcomes in HIV-infected women receiving TDF- vs. non-TDF-based ART during pregnancy. The relative risk for associations was pooled using a fixed-effects model. RESULTS: Sixteen studies met study inclusion criteria...
March 10, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28289509/perinatal-risk-factors-in-newborns-with-gastrointestinal-perforation
#15
Sandra Prgomet, Boris Lukšić, Zenon Pogorelić, Ivo Jurić, Vesna Čapkun, Adela Arapović, Nataša Boban
AIM: To investigate correlation of perinatal risk factors in newborns with gastrointestinal perforation (GIP). METHODS: Single-center retrospective cohort study was conducted between January 1990 and December 2012. Medical records on all newborns with GIP were reviewed (n = 35). Surgical records and histopathologic examination of all perforated intestine samples were also reviewed. RESULTS: The most common cause of GIP was necrotizing enterocolitis (51...
February 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28287305/parity-conditions-the-risk-for-low-birth-weight-after-maternal-exposure-to-air-pollution
#16
Anna Merklinger-Gruchala, Grazyna Jasienska, Maria Kapiszewska
Multiparous mothers have greater umbilical blood flow and thus more efficient transport of pollutants than primiparous mothers. We tested a hypothesis that multiparous mothers are more prone to have an infant with low birth weight (LBW) after prenatal exposure to air pollution. A study was conducted on a representative group of more than 74,000 singleton, live, full-term infants. Birth data were obtained from the birth registry, while pollution data were from an environmental monitoring system (Poland). Multiple comparisons were controlled by the false discovery rate procedure (FDR)...
2017: Biodemography and Social Biology
https://www.readbyqxmd.com/read/28284476/association-between-off-peak-hour-birth-and-neonatal-morbidity-and-mortality-among-very-low-birth-weight-infants
#17
Erik A Jensen, Scott A Lorch
OBJECTIVE: To assess the independent association between overnight or "off-peak" hour delivery and 3 neonatal morbidities strongly associated with childhood neurocognitive impairment. STUDY DESIGN: Retrospective population based cohort study of all infants with birth weights of 500-1499 g born without severe congenital anomalies in California or Pennsylvania between 2002 and 2009. Off-peak hour delivery was defined as birth between 12:00 a.m. and 6:59 a.m. The study outcomes were death; bronchopulmonary dysplasia, retinopathy of prematurity, and severe (grade 3 or 4) intraventricular hemorrhage among survivors; the composite of each morbidity or mortality; and the composite of death or 1 or more of the evaluated morbidities...
March 8, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28282531/bone-fracture-in-severe-small-for-gestational-age-extremely-low-birth-weight-infants-a-single-center-analysis
#18
Hidehiko Maruyama, Shoichiro Amari, Hideshi Fujinaga, Shuhei Fujino, Junko Nagasawa, Yuka Wada, Keiko Tsukamoto, Yushi Ito
INTRODUCTION: Bone fracture is a complication of extremely low birth weight infants (ELBWIs). This study aimed to analyze risk factors for bone fracture in a population of severe small-for-gestational-age (SGA) ELBWIs. METHODS: We retrospectively studied data from ELBWIs with a birth weight <1000g and <-2 standard deviations (SDs) born at the National Center for Child Health and Development, Japan, from 2013 to 2015. Infants were divided into fracture and control groups...
March 7, 2017: Early Human Development
https://www.readbyqxmd.com/read/28279149/somatic-growth-in-the-first-six-months-of-life-of-infants-exposed-to-maternal-smoking-in-pregnancy
#19
Mariana Lopes de Brito, Marina Nunes, Juliana Rombaldi Bernardi, Vera Lúcia Bosa, Marcelo Zubaran Goldani, Clécio Homrich da Silva
BACKGROUND: Some studies suggest a relationship between maternal smoking during pregnancy and not only intrauterine fetal growth restriction or low birth weight, but also with changes in the postnatal growth and development. The objective of the present study was to investigate the effects of smoking during pregnancy on infants growth in the first 6 months of life compared with a control group and a group with idiopathic intrauterine growth restriction. METHODS: Longitudinal observational study using a convenience sample of newborns divided into three groups: infants of smoking mothers (tobacco), with idiopathic intrauterine growth restriction (IUGR) and a control group...
March 9, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28279123/a-pioneering-study-oral-clarithromycin-treatment-for-feeding-intolerance-in-very-low-birth-weight-preterm-infants
#20
Selim Sancak, Tugba Gursoy, Abdulhamit Tuten, Didem Arman, Guner Karatekin, Fahri Ovali
PURPOSE: To examine the prokinetic effect of clarithromycin in very low birth weight (VLBW) preterm infants. MATERIALS AND METHODS: VLBW preterm infants who have not achieved half of the full enteral feeding in the second week of life were enrolled in the study. The infants enrolled in the study were randomized. 20 infants received oral clarithromycin (7.5 mg/kg, twice a day) and 20 control infants did not receive any treatment. RESULTS: Full enteral feeding was attained earlier in the clarithromycin group than in the control group [7 (6-9) vs 9 (9-11) days, respectively; p < 0...
March 9, 2017: Journal of Maternal-fetal & Neonatal Medicine
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