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https://www.readbyqxmd.com/read/28091867/arterial-aortic-stiffness-in-patients-with-resistant-hypertension-from-assessment-to-treatment
#1
REVIEW
James E Sharman, Pierre Boutouyrie, Stéphane Laurent
PURPOSE OF REVIEW: The purpose of the review is to examine whether measurement of aortic stiffness could be especially value-adding for risk stratification and treatment among patients with resistant hypertension (RH). RECENT FINDINGS: Adverse arterial remodeling and increased aortic stiffness is associated with RH, and it may be of additional clinical benefit to measure aortic stiffness in these patients. However, there is insufficient evidence to determine whether aortic stiffness is excessively high relative to the level of blood pressure (BP) among people with RH...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28089244/synchronous-ipsilateral-high-submuscular-placement-of-prosthetic-balloons-and-reservoirs
#2
Nicholas L Kavoussi, Matthias D Hofer, Boyd R Viers, Billy H Cordon, Ryan P Mooney, Travis J Pagliara, Jeremy M Scott, Allen F Morey
INTRODUCTION: Synchronous ipsilateral high submuscular placement of artificial urinary sphincter (AUS) pressure-regulating balloons (PRBs) and inflatable penile prosthesis (IPP) reservoirs in a single submuscular tunnel is a novel strategy that could be advantageous for patients who have had major pelvic surgery. AIM: To report our initial experience with synchronous ipsilateral vs bilateral placement of AUS PRBs and IPP reservoirs in men undergoing implant surgery...
January 11, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28086939/feasibility-study-for-the-non-invasive-blood-pressure-estimation-based-on-ppg-morphology-normotensive-subject-study
#3
Hangsik Shin, Se Dong Min
BACKGROUND: Blood pressure is a critical bio-signal and its importance has been increased with the aged society and the growth of cardiovascular disease population. However, most of hypertensive patients have been suffered the inconvenience in monitoring blood pressure in daily life because the measurement of the blood pressure depends on the cuff-based technique. Nowadays there are many trials to measure blood pressure without cuff, especially, photoplethysmography (PPG) based research is carried out in various ways...
January 10, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28077860/impact-of-cuff-positioning-on-blood-pressure-measurement-accuracy-may-a-specially-designed-cuff-make-a-difference
#4
Grzegorz Bilo, Oscar Sala, Carlotta Perego, Andrea Faini, Lan Gao, Anna Głuszewska, Juan Eugenio Ochoa, Dario Pellegrini, Laura Maria Lonati, Gianfranco Parati
During blood pressure (BP) measurement, the recommended positioning of the cuff bladder center is directly above the brachial artery. We investigated the relevance of incorrect cuff positioning during (1) auscultatory measurement with an appropriate or improperly small cuff and (2) oscillometric measurement with a wide-range cuff designed to guarantee accurate measurements regardless of position. In subjects with wide BP and arm circumference ranges, (1) auscultatory BP was repeatedly measured with a properly positioned cuff (reference) and, simultaneously, with an identical cuff placed on the other arm in either a correct or an incorrect position (test)...
January 12, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28077422/antxr2-knock-out-does-not-result-in-the-development-of-hypertension-in-rats
#5
Xiaoyan Liu, Wen Yuan, Jing Li, Lei Yang, Jun Cai
BACKGROUND: Our recent genetic study as well as robust evidences reported by previous genome-wide association studies (GWASs) have indicated that the single nucleotide polymorphism rs16998073, located near gene anthrax toxin receptor 2 (ANTXR2), was significantly associated with hypertension in Asians and Europeans. The aim of the present study was to determine whether ANTXR2 is the causal gene of hypertension at the 4q21 locus using an ANTXR2 knock-out model. METHODS: Relative expression of ANTXR2 in Wistar-Kyoto rats (WKYs) and spontaneously hypertensive rats (SHRs) were determined by real-time quantitative polymerase chain reaction and western blot analysis...
February 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28077421/aortic-wave-reflection-during-orthostatic-challenges-influence-of-body-position-and-venous-pooling
#6
William E Hughes, Darren P Casey
BACKGROUND: Aortic wave reflection (augmentation index; AIx) decreases during orthostatic challenges despite increased peripheral resistance, which is thought to be due to venous pooling. The purpose of this study was to examine if the decrease in AIx during an orthostatic challenge is due to venous pooling alone or body position manipulation. METHODS: Twenty-three young, healthy adults (11F/12M) participated in 3 separate orthostatic challenges (5 minutes each); 60° head-up tilt (HUT), 60° HUT with bilateral rhythmic blood pressure (BP) cuff inflation on calves (75 mm Hg) to minimize venous pooling, and lower body negative pressure (LBNP; -30 mm Hg) for venous pooling independent of body position...
February 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28075499/long-term-outcome-following-remote-ischemic-postconditioning-during-percutaneous-coronary-interventions-the-rip-pci-trial-long-term-follow-up
#7
Shahar Lavi, Nour Abu-Romeh, Sabrina Wall, Mistre Alemayehu, Ronit Lavi
The clinical value of ischemic conditioning during percutaneous coronary intervention (PCI) and mode of administration is controversial. Our aim was to assess the long-term effect of remote ischemic postconditioning among patients undergoing PCI. We randomized 360 patients undergoing PCI who presented with a negative troponin T at baseline into 3 groups: 2 groups received remote ischemic postconditioning (with ischemia applied to the arm in 1 group and to the thigh in the other group), and the third group acted as a control group...
January 11, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28072598/should-patients-with-higher-blood-pressure-variability-be-excluded-from-validation-studies-an-assessment-of-the-12-8-rule
#8
Raj S Padwal, Donna McLean, Jennifer Ringrose
To limit the inclusion of participants with increased blood pressure (BP) variability and presumably to avoid potential bias, the International Standards Organization BP device validation standard recommends exclusion of patients with a BP variability of more than 12/8 mmHg across reference readings. This '12/8 rule' is based on expert consensus and lacks empirical justification. In a post-hoc analysis of a study comparing two types of cuff designs carried out according to the International Standards Organization standard, we divided the study sample into patients who did not have (n=79) and patients who had (n=55) more than 12/8 mmHg variability...
January 7, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28065228/comparison-of-the-ambu-aura-i-with-the-air-q-intubating-laryngeal-airway-as-a-conduit-for-fiberoptic-guided-tracheal-intubation-in-children-with-ear-deformity
#9
Juan Zhi, Xiao-Ming Deng, Dong Yang, Chao Wen, Wen-Li Xu, Lei Wang, Jin Xu
Objective To compare the Ambu Aura-i with the Air-Q intubating laryngeal airway for fiberoptic-guided tracheal intubation in ear deformity children.Methods Totally 120 children who were scheduled for elective auricular reconstruction surgery requiring general anaesthesia with tracheal intubation were enrolled in this prospective study. They were randomized to receive either the Ambu Aura-i (Aura-i group) or Air-Q (Air-Q group). The time for successful tracheal intubation was assessed. The attempts for successful device insertion, leak pressures, cuff pressures, fiberoptic grade of laryngeal view, time for removal of the device after endotracheal intubation, and complications were recorded...
December 20, 2016: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28058813/outcomes-of-a-multi-community-hypertension-implementation-study-the-american-heart-association-s-check-change-control-program
#10
Monique L Anderson, Rachel Peragallo Urrutia, Emily C O'Brien, Nancy M Allen LaPointe, Alexander J Christian, Lisa A Kaltenbach, Laura E Webb, Angel M Alexander, Paramita Saha Chaudhuri, Juliana Crawford, Patrick Wayte, Eric D Peterson
: Single-site, intensive, community-based blood pressure (BP) intervention programs have led to BP improvements. The authors examined the American Heart Association's Check. Change. CONTROL: (CCC) program (4069 patients/18 cities) to determine whether BP interventions can effectively be scaled to multiple communities, using a simplified template and local customization. Effectiveness was evaluated at each site via site percent enrollment goals, participant engagement, and BP change from first to last measurement...
January 6, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28058141/ultrasonographic-measurement-of-subglottic-diameter-for-paediatric-cuffed-endotracheal-tube-size-selection-feasibility-report
#11
Demet Altun, Mukadder Orhan Sungur, Achmet Ali, Emre Sertaç Bingül, Tülay Özkan Seyhan, Emre Çamcı
OBJECTIVE: The aim of this feasibility study was to investigate the first attempt success of ultrasonography (USG) in paediatric patients in predicting an appropriate cuffed endotracheal tube (ETT) size. METHODS: Fifty children who were 1-10 years of age and who received general anaesthesia with endotracheal intubation for adenoidectomy or adenotonsillectomy were enrolled in the study. In all participants, the transverse diameter of the subglottic airway was measured with USG at the cricoid level without ventilation...
December 2016: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28053139/cuff-pressure-pain-detection-is-associated-with-both-sex-and-physical-activity-level-in-nonathletic-healthy-subjects
#12
Dag Lemming, Björn Börsbo, Anna Sjörs, Eva-Britt Lind, Lars Arendt-Nielsen, Thomas Graven-Nielsen, Björn Gerdle
: PURPOSE : The aim of this study was to evaluate pressure pain sensitivity on leg and arm in 98 healthy persons (50 women) using cuff algometry. Furthermore, associations with sex and physical activity level were investigated. METHOD:  Normal physical activity level was defined as Godin Leisure-Time Exercise Questionnaire (GLTEQ) score ≤ 45 and high activity level as GLTEQ > 45. A pneumatic double-chamber cuff was placed around the arm or leg where a single chamber was inflated...
January 4, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28043670/vascular-aging-and-hypertension-implications-for-the-clinical-application-of-central-blood-pressure
#13
REVIEW
Hao-Min Cheng, Sungha Park, Qifang Huang, Satoshi Hoshide, Ji-Guang Wang, Kazuomi Kario, Chang-Gyu Park, Chen-Huan Chen
Vascular aging may be responsible for the high residual lifetime risk for hypertension in the middle-aged and elderly individuals. Increased arterial stiffness and wave reflection has been recognized as the dominant hemodynamic manifestations of vascular aging, and both are major determinants of central blood pressure (BP) and independent predictors for incident hypertension. Because central BP is strongly linearly associated with age, it can be regarded as an integrated marker for vascular aging. Central BP can be measured noninvasively using various techniques, including the convenient cuff-based oscillometric central BP monitors...
December 27, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28034895/impaired-aortic-contractility-to-uridine-adenosine-tetraphosphate-in-angiotensin-ii-induced-hypertensive-mice-receptor-desensitization
#14
Zhichao Zhou, Vishal R Yadav, Changyan Sun, Bunyen Teng, Jamal S Mustafa
OBJECTIVE: We previously showed that uridine adenosine tetraphosphate (Up4A)-mediated aortic contraction is partly mediated through purinergic P2X1 receptors (P2X1R). It has been reported that the plasma level of Up4A is elevated in hypertensive patients, implying a potential role for Up4A-P2X1R signaling in hypertension. This study investigated the vasoactive effect of Up4A in aortas isolated from angiotensin (Ang) II-infused (21 days) hypertensive mice. METHODS: Blood pressure was measured by tail cuff plethysmography...
December 29, 2016: American Journal of Hypertension
https://www.readbyqxmd.com/read/28034583/differential-hypertensive-protease-expression-in-the-thoracic-versus-abdominal-aorta
#15
Jean Marie Ruddy, Adam W Akerman, Denise Kimbrough, Elizabeth K Nadeau, Robert E Stroud, Rupak Mukherjee, John S Ikonomidis, Jeffrey A Jones
BACKGROUND: Hypertension (HTN), which is a major risk factor for cardiovascular morbidity and mortality, can drive pathologic remodeling of the macro- and microcirculation. Patterns of aortic pathology differ, however, suggesting regional heterogeneity of the pressure-sensitive protease systems triggering extracellular matrix remodeling in the thoracic (TA) and abdominal aortas (AA). This study tested the hypothesis that the expression of two major protease systems (matrix metalloproteinases [MMPs] and cathepsins) in the TA and AA would be differentially affected with HTN...
December 26, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28033257/incidental-left-main-bronchus-obstruction-during-left-sided-double-lumen-tube-intubation-of-a-patient-with-an-unrecognized-tracheal-bronchus-a-case-report
#16
Ho Bum Cho, Hyoung June Kim, Hyung Youn Gong, Mun Gyu Kim, Sang Ho Kim
INTRODUCTION: Tracheal bronchus is a right-sided anomalous bronchus arising from the trachea above the main carina and occurs in 0.1% to 2% of the general population. CASE PRESENTATION: We present a case of left main bronchus obstruction during a left-sided double-lumen tube intubation in a patient with an unrecognized tracheal bronchus. After the intubation, to confirm the position of the tube, we observed what we believed was the carina with a fiberoptic bronchoscope, but it was a site between the tracheal bronchus and the right main bronchus...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28028715/study-on-the-intervention-effects-of-pinggan-prescription-on-spontaneously-hypertensive-rats-based-on-metabonomic-combined-with-pharmacodynamic-methods
#17
Jun Xie, Hai-Qiang Jiang, Yun-Lun Li, Lei Nie, Hong-Lei Zhou, Wen-Qing Yang
OBJECTIVE: To investigate the effects of Pinggan Prescription (, PGP) on hypertension by the associated methods of metabonomic and pharmacodynamic. METHODS: A total of 32 male spontaneously hypertensive rats (SHRs) were randomly divided into two groups by using the random number table method: a treatment group (n=18) and a model group (n=14). The Wistar rats (n=14) were used as the normal group. Different prescription were used to intervene three groups: the treatment group in which PGP extract was administered orally at a dose of 18...
December 27, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28011881/alterations-in-the-gut-microbiota-can-elicit-hypertension-in-rats
#18
Sareema Adnan, James W Nelson, Nadim J Ajami, Venugopal R Venna, Joseph F Petrosino, Robert M Bryan, David J Durgan
Gut dysbiosis has been linked to cardiovascular diseases including hypertension. We tested the hypothesis that hypertension could be induced in a normotensive strain of rats or attenuated in a hypertensive strain of rats by exchanging the gut microbiota between the two strains. Cecal contents from spontaneously hypertensive stroke prone rats (SHRSP) were pooled. Similarly, cecal contents from normotensive WKY rats were pooled. Four week old recipient WKY and SHR rats, previously treated with antibiotics to reduce the native microbiota, were gavaged with WKY or SHRSP microbiota, resulting in four groups; WKY with WKY microbiota (WKY g-WKY), WKY with SHRSP microbiota (WKY g-SHRSP), SHR with SHRSP microbiota (SHR g-SHRSP), and SHR with WKY microbiota (SHR g-WKY)...
December 23, 2016: Physiological Genomics
https://www.readbyqxmd.com/read/28007380/the-effect-of-transesophageal-echocardiography-probe-placement-on-intracuff-pressure-of-an-endotracheal-tube-in-infants-and-children
#19
Mineto Kamata, Mumin Hakim, Dmitry Tumin, Senthil G Krishna, Aymen Naguib, Joseph D Tobias
OBJECTIVES: To evaluate the effects of transesophageal echocardiography (TEE) probe insertion on the endotracheal cuff pressure (CP). DESIGN: Prospective observational study. SETTING: Single standing, not-for-profit pediatric hospital. PARTICIPANTS: A total of 80 pediatric patients (aged 6 days to 18.4 years) who underwent cardiac surgery and intraoperative TEE. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Following anesthesia induction and endotracheal intubation, the CP was recorded at 4 points: before the insertion of the TEE (P1), at TEE insertion (P2), during TEE examination (P3), and after the probe was advanced into the stomach (P4)...
October 4, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28005701/effect-of-short-term-exercise-training-on-brain-derived-neurotrophic-factor-signaling-in-spontaneously-hypertensive-rats
#20
Alice Monnier, Philippe Garnier, Aurore Quirie, Nicolas Pernet, Céline Demougeot, Christine Marie, Anne Prigent-Tessier
OBJECTIVE: Decreased brain-derived neurotrophic factor (BDNF) level has been reported in the hippocampus of hypertensive rats. The present study explored whether brain neurons and/or endothelial cells are targeted by hypertension with respect to BDNF expression and the potential of physical exercise to cope with hypertension. METHODS: Physical exercise was induced in spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) rats. The hippocampus of sedentary and exercised rats (n = 6 for each group) were used for western blots to assess proBDNF, mature BDNF (mBDNF), tropomyosin-related kinase B (TrkB), P-TrkB (TrkB phosphorylated at tyrosine 816), synaptophysin, endothelial nitric oxide synthase (eNOS) and eNOS phosphorylated at serine 1177 protein levels...
February 2017: Journal of Hypertension
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