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https://www.readbyqxmd.com/read/28922139/3d-printed-multiplexed-electrospinning-sources-for-large-scale-production-of-aligned-nanofiber-mats-with-small-diameter-spread
#1
Erika García-López, Daniel Olvera-Trejo, Luis F Velásquez-García
We report the design, fabrication, and characterization of novel, low-cost, and modular miniaturized nanofiber electrospinning sources for the scalable production of non-woven aligned nanofiber mats with low diameter variation. The devices are monolithic arrays of electrospinning emitters made via stereolithography; the emitters are arranged so each element has an independent line of sight to a rotating collector surface. Linear and zigzag emitter packing were evaluated using a PEO solution with the aim of maximizing the throughput of nanofibers with the smallest diameter and narrowest distribution...
September 18, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28920439/multi-material-3d-printing-of-graphene-based-electrodes-for-electrochemical-energy-storage-using-thermo-responsive-inks
#2
Victoria García Rocha, Esther Garcia-Tunon, Cristina Botas, Foivos Markoulidis, Ezra Feilden, Eleonora D'Elia, Na Ni, Milo Sebastian Peter Shaffer, Eduardo Saiz
The current lifestyles, increasing population and limited resources result in energy research being at the forefront of worldwide grand challenges, increasing the demand for sustainable and more efficient energy devices. In this context, Additive Manufacturing brings the possibility of making electrodes and electrical energy storage (EES) devices in any desired 3D shape and dimensions, while preserving the multifunctional properties of the active materials in terms of surface area and conductivity. This paves the way to optimized and more efficient designs for energy devices...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28919383/prediction-of-air-entrapment-in-tableting-an-approximate-solution
#3
Antonios Zavaliangos, Jeffrey M Katz, Dominick Daurio, Michael Johnson, Armen Pirjanian, Fernando Alvarez-Nunez
Αn approximate solution is presented for the prediction of air entrapment during tableting. Assuming weak coupling of the deformation of the solid phase, the flow of interstitial air and a set of reasonable additional geometric assumptions, the general problem is reduced to one dimension. Experimental values of air permeability through tablet specimens of commonly used pharmaceutical excipients were obtained using a 3D printed test cell outfitted to a powder rheometer. Using these values, combined with a numerical solution of the governing partial differential equation, parametric studies are presented that demonstrate the importance of permeability, compaction speed, tablet size, and punch-die tolerance on air entrapment...
September 14, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28917939/preparation-and-characterization-of-gelatin-%C3%AE-tcp-sf-biocomposite-scaffold-for-bone-tissue-regeneration
#4
JunTae Huh, JiUn Lee, WonJin Kim, Miji Yeo, GeunHyung Kim
In this study, we suggest a new biocomposite scaffold composed of gelatin/α-TCP (tricalcium phosphate)/SF (silk-fibroin) (GTS) which has enhanced mechanical strength and high level of cellular activity. To fabricate GTS scaffold, a temperature-controlled 3D printing process was used and appropriate printing conditions were selected based on rheological data. To show the feasibility as a biomedical scaffold for bone tissue regeneration, the various physical and biological results, using MG63 (osteoblast-like cells), of the GTS scaffold were compared with those of a pure gelatin (G) and gelatin/α-TCP (GT) composite scaffold...
September 13, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28917677/interventional-correction-of-sinus-venosus-atrial-septal-defect-and-partial-anomalous-pulmonary-venous-drainage-procedural-planning-using-3d-printed-models
#5
Mari Nieves Velasco Forte, Nick Byrne, Israel Valverde, Gorka Gomez Ciriza, Antony Hermuzi, Pimpak Prachasilchai, Gur Mainzer, Kuberan Pushparajah, Markus Henningsson, Tarique Hussain, Shakeel Qureshi, Eric Rosenthal
No abstract text is available yet for this article.
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28916883/different-post-processing-conditions-for-3d-bioprinted-%C3%AE-tricalcium-phosphate-scaffolds
#6
Liciane Sabadin Bertol, Rodrigo Schabbach, Luis Alberto Loureiro Dos Santos
The development of 3D printing hardware, software and materials has enabled the production of bone substitute scaffolds for tissue engineering. Calcium phosphates cements, such as those based on α-tricalcium phosphate (α-TCP), have recognized properties of osteoinductivity, osteoconductivity and resorbability and can be used to 3D print scaffolds to support and induce tissue formation and be replaced by natural bone. At present, however, the mechanical properties found for 3D printed bone scaffolds are only satisfactory for non-load bearing applications...
September 15, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28916103/controlled-synchronized-actuation-of-microdroplets-by-gravity-in-a-superhydrophobic-3d-printed-device
#7
P E Oomen, J P S H Mulder, E Verpoorte, R D Oleschuk
Droplet manipulation over open surfaces allows one to perform assays with a large degree of control and high throughput, making them appealing for applications in drug screening or (bio)analysis. However, the design, manufacturing and operation of these systems comes with high technical requirements. In this study we employ a commercial, low-friction, superhydrophobic coating, Ultra-Ever Dry(®), on a 3D-printed microfluidic device. The device features individual droplet compartments, which allow the manipulation of discrete droplets (10-50 μL) actuated by gravity alone...
October 2, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28914992/an-effective-thermal-therapy-against-cancer-using-an-e-jet-3d-printing-method-to-prepare-implantable-magnetocaloric-mats
#8
Yikun Yang, Chunyi Tong, Juchang Zhong, Ruiying Huang, Weihong Tan, Zhikai Tan
Magnetic hyperthermia has been rapidly developed as a potential cancer treatment in recent years. Artificially induced hyperthermia close to a tumor can raise the temperature to 45°C causing tumor cell death. Herein, we introduce a novel method for rapid preparation of anti-cancer magnetocaloric PCL/Fe3 O4 mats capable of high-performance hyperthermia using E-jet 3D printing technology. Our 3D printed mats not only maintained the heating efficiency of traditional techniques for magnetic hyperthermia but also prolonged the effective therapy in vivo...
September 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28914982/production-of-accurate-skeletal-models-of-domestic-animals-using-three-dimensional-scanning-and-printing-technology
#9
Fangzheng Li, Chunying Liu, Xuexiong Song, Yanjun Huan, Shansong Gao, Zhongling Jiang
Access to adequate anatomical specimens can be an important aspect in learning the anatomy of domestic animals. In this study, the authors utilized a structured light scanner and fused deposition modeling (FDM) printer to produce highly accurate animal skeletal models. First, various components of the bovine skeleton, including the femur, the fifth rib, and the sixth cervical (C6) vertebra were used to produce digital models. These were then used to produce 1:1 scale physical models with the FDM printer. The anatomical features of the digital models and three-dimensional (3D) printed models were then compared with those of the original skeletal specimens...
September 15, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28912242/fabrication-of-fillable-microparticles-and-other-complex-3d-microstructures
#10
Kevin J McHugh, Thanh D Nguyen, Allison R Linehan, David Yang, Adam M Behrens, Sviatlana Rose, Zachary L Tochka, Stephany Y Tzeng, James J Norman, Aaron C Anselmo, Xian Xu, Stephanie Tomasic, Matthew A Taylor, Jennifer Lu, Rohiverth Guarecuco, Robert Langer, Ana Jaklenec
Three-dimensional (3D) microstructures created by microfabrication and additive manufacturing have demonstrated value across a number of fields, ranging from biomedicine to microelectronics. However, the techniques used to create these devices each have their own characteristic set of advantages and limitations with regards to resolution, material compatibility, and geometrical constraints that determine the types of microstructures that can be formed. We describe a microfabrication method, termed StampEd Assembly of polymer Layers (SEAL), and create injectable pulsatile drug-delivery microparticles, pH sensors, and 3D microfluidic devices that we could not produce using traditional 3D printing...
September 15, 2017: Science
https://www.readbyqxmd.com/read/28906599/dual-extrusion-3d-printing-of-anatomical-models-for-education
#11
Michelle L Smith, James F X Jones
Two material 3D printing is becoming increasingly popular, inexpensive and accessible. In this paper, freely available printable files and dual extrusion fused deposition modelling were combined to create a number of functional anatomical models. To represent muscle and bone FilaFlex(3D) flexible filament and polylactic acid (PLA) filament were extruded respectively via a single 0.4 mm nozzle using a Big Builder printer. For each filament, cubes (5 mm(3) ) were printed and analyzed for X, Y, and Z accuracy...
September 14, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28906525/stereolithographic-printing-of-ionically-crosslinked-alginate-hydrogels-for-degradable-biomaterials-and-microfluidics
#12
Thomas M Valentin, Susan E Leggett, Po-Yen Chen, Jaskiranjeet K Sodhi, Lauren H Stephens, Hayley D McClintock, Jea Yun Sim, Ian Y Wong
3D printed biomaterials with spatial and temporal functionality could enable interfacial manipulation of fluid flows and motile cells. However, such dynamic biomaterials are challenging to implement since they must be responsive to multiple, biocompatible stimuli. Here, we show stereolithographic printing of hydrogels using noncovalent (ionic) crosslinking, which enables reversible patterning with controlled degradation. We demonstrate this approach using sodium alginate, photoacid generators and various combinations of divalent cation salts, which can be used to tune the hydrogel degradation kinetics, pattern fidelity, and mechanical properties...
September 14, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28906410/augmented-reality-navigation-in-open-surgery-for-hilar-cholangiocarcinoma-resection-with-hemihepatectomy-using-video-based-in-situ-three-dimensional-anatomical-modeling-a-case-report
#13
Rui Tang, Longfei Ma, Canhong Xiang, Xuedong Wang, Ang Li, Hongen Liao, Jiahong Dong
RATIONALE: Patients who undergo hilar cholangiocarcinoma (HCAC) resection with concomitant hepatectomy have a high risk of postoperative morbidity and mortality due to surgical trauma to the hepatic and biliary vasculature. PATIENT CONCERNS: A 58-year-old Chinese man with yellowing skin and sclera, abdominal distension, pruritus, and anorexia for approximately 3 weeks. DIAGNOSES: Magnetic resonance cholangiopancreatography and enhanced computed tomography (CT) scanning revealed a mass over the biliary tree at the porta hepatis, which diagnosed to be s a hilar cholangiocarcinoma...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28906326/tissue-engineering-strategies-for-auricular-reconstruction
#14
Michael J Schroeder, Mark S Lloyd
Simulating natural characteristics and aesthetics in reconstructed ears has provided a complex 3-dimensional puzzle for those treating patients with microtia. Costochondral grafts remain the gold standard for autologous reconstruction. However, other options such as Medpor and prosthetics are indicated depending on patient circumstances and personal choice. Research into tissue engineering offers an alternative method to a traditional surgical approach that may reduce donor-site morbidity. However, tissue engineering for microtia reconstruction brings new challenges such as cell sourcing, promotion of chondrogenesis, scaffold vascularization, and prevention of scaffold contraction...
September 12, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28905812/carbon-fiber-on-polyimide-ultra-microelectrodes
#15
Wintrop F Gillis, Charles A Lissandrello, Jun Shen, Ben W Pearre, Alket Mertiri, Felix Deku, Stuart Cogan, Bradley J Holinski, Daniel J Chew, Alice E White, Timothy M Otchy, Timothy Gardner
OBJECTIVE: Most preparations for making neural recordings degrade over time and eventually fail due to insertion trauma and reactive tissue response. The magnitudes of these responses are thought to be related to the electrode size (specifically, the cross-sectional area), the relative stiffness of the electrode, and the degree of tissue tolerance for the material. Flexible carbon fiber ultra-microelectrodes have a much smaller cross-section than traditional electrodes and low tissue reactivity, and thus may enable improved longevity of neural recordings in the central and peripheral nervous systems...
September 14, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28905390/validation-of-the-gatortail-method-for-accurate-sizing-of-pulmonary-vessels-from-3d-medical-images
#16
Walter G O'Dell, Anne K Gormaley, David A Prida
PURPOSE: Detailed characterization of changes in vessel size is crucial for the diagnosis and management of a variety of vascular diseases. Because clinical measurement of vessel size is typically dependent on the radiologist's subjective interpretation of the vessel borders, it is often prone to high inter- and intra-user variability. Automatic methods of vessel sizing have been developed for two-dimensional images but a fully three-dimensional (3D) method suitable for vessel sizing from volumetric X-ray computed tomography (CT) or magnetic resonance imaging has heretofore not been demonstrated and validated robustly...
September 14, 2017: Medical Physics
https://www.readbyqxmd.com/read/28901689/prevascularization-of-3d-printed-bone-scaffolds-by-bioactive-hydrogels-and-cell-co-culture
#17
Mitchell A Kuss, Shaohua Wu, Ying Wang, Jason B Untrauer, Wenlong Li, Jung Yul Lim, Bin Duan
Vascularization is a fundamental prerequisite for large bone construct development and remains one of the main challenges of bone tissue engineering. Our current study presents the combination of 3D printing technique with a hydrogel-based prevascularization strategy to generate prevascularized bone constructs. Human adipose derived mesenchymal stem cells (ADMSC) and human umbilical vein endothelial cells (HUVEC) were encapsulated within our bioactive hydrogels, and the effects of culture conditions on in vitro vascularization were determined...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28901301/expert-consensus-workshop-report-guideline-for-three-dimensional-printing-template-assisted-computed-tomography-guided-125-i-seeds-interstitial-implantation-brachytherapy
#18
REVIEW
Junjie Wang, Fujun Zhang, Jinhe Guo, Shude Chai, Guangjun Zheng, Kaixian Zhang, Anyan Liao, Ping Jiang, Yuliang Jiang, Zhe Ji
Radioactive 125I seeds (RIS) interstitial implantation brachytherapy has been a first-line treatment for early-stage cancer of the prostate gland. However, its poor accuracy and homogeneity has limited its indication and hampered its popularization for a long time. Intriguingly, scholars based in China introduced computed tomography (CT)-guided technology to improve the accuracy and homogeneity of RIS implantation and broadened the indications. Then, they creatively designed and introduced three-dimensional printing coplanar template (3D-PCT) and 3D printing noncoplanar template (3D-PNCT) into the practice of RIS implantation...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28899562/the-design-production-and-clinical-application-of-3d-patient-specific-implants-with-drilling-guides-for-acetabular-surgery
#19
B J Merema, J Kraeima, K Ten Duis, K W Wendt, R Warta, E Vos, R H Schepers, M J H Witjes, F F A IJpma
An innovative procedure for the development of 3D patient-specific implants with drilling guides for acetabular fracture surgery is presented. By using CT data and 3D surgical planning software, a virtual model of the fractured pelvis was created. During this process the fracture was virtually reduced. Based on the reduced fracture model, patient-specific titanium plates including polyamide drilling guides were designed, 3D printed and milled for intra-operative use. One of the advantages of this procedure is that the personalised plates could be tailored to both the shape of the pelvis and the type of fracture...
August 30, 2017: Injury
https://www.readbyqxmd.com/read/28899557/can-the-recovery-of-lower-limb-fractures-be-achieved-by-use-of-3d-printing-mirror-model
#20
Wenxi Zhang, Yueping Ji, Xinming Wang, Jie Liu, Dong Li
INTRODUCTION: The mirror imaging 3D printing model can be used a as a reference for anatomical reduction in unilateral lower limb fractures. However, the premise of using mirror technology is that the bilateral lower limb bones are similar enough. Because one side had a fracture, it was impossible to compare this directly to the other side. Usually, surgeons think that the bilateral bones are symmetrical and use mirror technology without judging their symmetry. METHODS: In patients with a unilateral lower limb bone fracture, we measured the long axis and short axis of the three selected transverse sections of the bilateral long bone for comparison to judge the symmetry of the bilateral long bones on CT images...
September 6, 2017: Injury
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