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Heart Rate Variability and cardiovascular disease

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https://www.readbyqxmd.com/read/27886710/automated-diagnosis-of-coronary-artery-disease-cad-patients-using-optimized-svm
#1
Azam Davari Dolatabadi, Siamak Esmael Zadeh Khadem, Babak Mohammadzadeh Asl
BACKGROUND AND OBJECTIVE: Currently Coronary Artery Disease (CAD) is one of the most prevalent diseases, and also can lead to death, disability and economic loss in patients who suffer from cardiovascular disease. Diagnostic procedures of this disease by medical teams are typically invasive, although they do not satisfy the required accuracy. METHODS: In this study, we have proposed a methodology for the automatic diagnosis of normal and Coronary Artery Disease conditions using Heart Rate Variability (HRV) signal extracted from electrocardiogram (ECG)...
January 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27873227/the-relationship-between-aortic-root-size-and-hypertension-an-unsolved-conundrum
#2
Giuseppe Mulè, Emilio Nardi, Massimiliano Morreale, Antonella Castiglia, Giulio Geraci, Dario Altieri, Valentina Cacciatore, Margherita Schillaci, Francesco Vaccaro, Santina Cottone
Thoracic aortic aneurysms rupture and dissection are among the most devastating vascular diseases, being characterized by elevated mortality, despite improvements in diagnostic imaging and surgical techniques.An increased aortic root diameter (ARD) represents the main risk factor for thoracic aortic dissection and rupture and for aortic valve regurgitation.Even though arterial hypertension is commonly regarded as a predisposing condition for the development of thoracic aorta aneurysms, the role of blood pressure (BP) as determinant of aortic root enlargement is still controversial...
November 22, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27861527/the-impact-of-early-life-stress-on-growth-and-cardiovascular-risk-a-possible-example-for-autonomic-imprinting
#3
Reiner Buchhorn, Sebastian Meint, Christian Willaschek
INTRODUCTION: Early life stress is imprinting regulatory properties with life-long consequences. We investigated heart rate variability in a group of small children with height below the third percentile, who experienced an episode of early life stress due to heart failure or intra uterine growth retardation. These children appear to develop autonomic dysfunction in later life. RESULTS: Compared to the healthy control group heart rate variability (HRV) is reduced on average in a group of 101 children with short stature...
2016: PloS One
https://www.readbyqxmd.com/read/27843848/impact-of-disease-control-and-co-existing-risk-factors-on-heart-rate-variability-in-gujarati-type-2-diabetics-an-observational-study
#4
Jayesh Dalpatbhai Solanki, Sanket D Basida, Hemant B Mehta, Sunil J Panjwani, Bhakti P Gadhavi, Pathik Patel
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a proven threat of cardiac dysautonomia with paucity of studies from India. Poor disease control makes it further worse with co-existence of hypertension in majority. Heart rate variability (HRV) is a validated noninvasive tool to assess cardiac autonomic status. AIM: We studied HRV parameters of type 2 diabetics looking for effects of disease control and other co-existing risk factors. MATERIALS AND METHODS: Ninety-eight hypertensive and forty normotensive under-treatment, Gujarati type 2 diabetics were evaluated for disease control and risk stratification...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27836300/methods-of-assessment-of-the-post-exercise-cardiac-autonomic-recovery-a-methodological-review
#5
REVIEW
Tiago Peçanha, Rhenan Bartels, Leandro C Brito, Marcelle Paula-Ribeiro, Ricardo S Oliveira, Jeffrey J Goldberger
The analysis of post-exercise cardiac autonomic recovery is a practical clinical tool for the assessment of cardiovascular health. A reduced heart rate recovery - an indicator of autonomic dysfunction - has been found in a broad range of cardiovascular diseases and has been associated with increased risks of both cardiac and all-cause mortality. For this reason, over the last several years, non-invasive methods for the assessment of cardiac autonomic recovery after exercise - either based on heart rate recovery or heart rate variability indices - have been proposed...
October 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27830572/inflammation-associated-co-morbidity-between-depression-and-cardiovascular-disease
#6
Angelos Halaris
Morbidity and mortality of cardiovascular disease (CVD) is exceedingly high worldwide. Depressive illness is a serious psychiatric illness that afflicts a significant portion of the world population. Epidemiological studies have confirmed the high co-morbidity between these two disease entities. The co-morbidity is bidirectional and the mechanisms responsible for it are complex and multifaceted. In addition to genetic, biological systems, psychosocial, and behavioral factors that are involved include the central and autonomic nervous systems, the neuroendocrine, immune, and the vascular and hematologic systems...
November 10, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27802074/gestational-chronodisruption-impairs-circadian-physiology-in-rat-male-offspring-increasing-the-risk-of-chronic-disease
#7
Natalia Mendez, Diego Halabi, Carlos Spichiger, Esteban R Salazar, Karina Vergara, Pamela Alonso-Vasquez, Pamela Carmona, Jose M Sarmiento, Hans G Richter, Maria Seron-Ferre, Claudia Torres-Farfan
Chronic exposure to light at night, as in shift work, alters biological clocks (chronodisruption), negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and fetal circadian systems could be a key factor determining a fitting health in adults. We propose that chronic photoperiod shift (CPS) during pregnancy alter maternal circadian rhythms and impair circadian physiology in the adult offspring, increasing health risks. Pregnant rats were exposed to normal photoperiod (12 h light, 12 h dark) or to CPS until 85% of gestation...
December 2016: Endocrinology
https://www.readbyqxmd.com/read/27799236/effects-of-statin-on-arrhythmia-and-heart-rate-variability-in-healthy-persons-with-48-hour-sleep-deprivation
#8
Wei Ren Chen, Hong Bin Liu, Yuan Sha, Yang Shi, Hao Wang, Da Wei Yin, Yun Dai Chen, Xiang Min Shi
BACKGROUND: It has been reported that sleep deprivation is associated with cardiac autonomic disorder, inflammation, and oxidative stress. Statins have significant cardiovascular protective effects in patients with cardiovascular disease. This study aimed to investigate the protective effect of statins on arrhythmia and heart rate variability in young healthy persons after 48-hour sleep deprivation. METHODS AND RESULTS: This study enrolled 72 young healthy participants aged 26...
October 31, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27797930/effects-of-liraglutide-on-heart-rate-and-heart-rate-variability-a-randomized-double-blind-placebo-controlled-crossover-study
#9
Preman Kumarathurai, Christian Anholm, Bjørn S Larsen, Rasmus Huan Olsen, Sten Madsbad, Ole Kristiansen, Olav W Nielsen, Steen B Haugaard, Ahmad Sajadieh
OBJECTIVE: Reduced heart rate variability (HRV) and increased heart rate (HR) have been associated with cardiovascular mortality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) increase HR, and studies have suggested that they may reduce HRV. We examined the effect of the GLP-1 RA liraglutide on HRV and diurnal variation of HR in overweight patients with newly diagnosed type 2 diabetes (T2D) and stable coronary artery disease (CAD). RESEARCH DESIGN AND METHODS: Liraglutide or placebo was administrated to a backbone therapy of metformin in this double-blind, placebo-controlled 12 + 12-week crossover study...
October 19, 2016: Diabetes Care
https://www.readbyqxmd.com/read/27786404/risk-of-contrast-induced-nephropathy-in-diabetic-patients-affected-by-critical-limb-ischemia-and-diabetic-foot-ulcers-treated-by-percutaneous-transluminal-angioplasty-of-lower-limbs
#10
Marco Meloni, Laura Giurato, Valentina Izzo, Matteo Stefanini, Roberto Gandini, Luigi Uccioli
BACKGROUND: To evaluate the risk of contrast induced nephropathy (CIN) in diabetic patients with critical limb ischemia (CLI) and foot ulcers (FUs) treated by percutaneous transluminal angioplasty (PTA) of lower limbs. METHODS: The study group was composed of 145 diabetic patients who underwent a limb salvage protocol because of CLI and FUs between 2012 and 2015. All patients received a prophylactic strategy against the administration of contrast medium (CM). Serum creatinine levels (SCr) were evaluated the day of procedure and for three days after...
October 27, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27781180/a-pilot-study-examining-the-effects-of-low-volume-high-intensity-interval-training-and-continuous-low-to-moderate-intensity-training-on-quality-of-life-functional-capacity-and-cardiovascular-risk-factors-in-cancer-survivors
#11
Kellie Toohey, Kate L Pumpa, Leonard Arnolda, Julie Cooke, Desmond Yip, Paul S Craft, Stuart Semple
PURPOSE: The aim of this study was to evaluate the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular disease risk factors in cancer survivors. METHODS: Cancer survivors within 24 months post-diagnosis were randomly assigned into the low-volume high-intensity interval training group (n = 8) or the continuous low to moderate intensity training group (n = 8) group for 36 sessions (12 weeks) of supervised exercise...
2016: PeerJ
https://www.readbyqxmd.com/read/27772769/cardiovascular-dysfunction-in-untreated-parkinson-s-disease-a-multi-modality-assessment
#12
Stefano Strano, Alessandra Fanciulli, Massimiliano Rizzo, Paolo Marinelli, Paolo Palange, Dorina Tiple, Giuseppe De Vincentis, Giovanni Calcagnini, Federica Censi, Giuseppe Meco, Carlo Colosimo
BACKGROUND: The clinical presentation of Parkinson's disease (PD) includes a wide spectrum of non-motor features, including cardiovascular autonomic failure. OBJECTIVE: To evaluate cardiovascular autonomic status and cardiac functional capacity in drug-naïve PD patients. METHODS: 18 newly-diagnosed PD patients underwent laboratory cardiovascular autonomic function tests using power spectral analysis of the R-R interval, blood pressure (BP) short-term variability and non-invasive baroreflex sensitivity (BRS)...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27770662/menstrual-cycle-related-variation-in-autonomic-nervous-system-functioning-in-women-in-the-early-menopausal-transition-with-and-without-insomnia-disorder
#13
Massimiliano de Zambotti, John Trinder, Ian M Colrain, Fiona C Baker
Insomnia is considered a hyperarousal disorder, in which several psychophysiological domains including the autonomic nervous system (ANS) are over-activated, potentially contributing to increased risk for cardiovascular (CV) disease. Here, we aimed to determine whether insomnia that develops in the context of the transition to menopause (menopausal transition insomnia, MTI) is similarly characterized by autonomic arousal. We also took into account modulation of the ANS by the hormonal changes of the menstrual cycle, a factor that has not previously been considered in studies on insomnia...
January 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27765048/correlation-between-health-related-quality-of-life-in-the-physical-domain-and-heart-rate-variability-in-asymptomatic-adults
#14
Wan-Chun Lu, Nian-Sheng Tzeng, Yu-Chen Kao, Chin-Bin Yeh, Terry B J Kuo, Chuan-Chia Chang, Hsin-An Chang
BACKGROUND: Reduced health-related quality of life in the physical domain (HRQOLphysical) has been reported to increase risks for cardiovascular disease (CVD); however, the mechanism underlying this phenomenon is still unclear. The autonomic nervous system (ANS) that connects the body and mind is a biologically plausible candidate to investigate this mechanism. The aim of our study is to examine whether the HRQOLphysical independently contributes to heart rate variability (HRV), which reflects ANS activity...
October 21, 2016: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/27761124/executive-cognitive-functioning-and-cardiovascular-autonomic-regulation-in-a-population-based-sample-of-working-adults
#15
Cecilia U D Stenfors, Linda M Hanson, Töres Theorell, Walter S Osika
Objective: Executive cognitive functioning is essential in private and working life and is sensitive to stress and aging. Cardiovascular (CV) health factors are related to cognitive decline and dementia, but there is relatively few studies of the role of CV autonomic regulation, a key component in stress responses and risk factor for cardiovascular disease (CVD), and executive processes. An emerging pattern of results from previous studies suggest that different executive processes may be differentially associated with CV autonomic regulation...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27754552/a-prospective-study-of-patients-with-refractory-angina-outcomes-and-the-role-of-high-sensitivity-troponin-t
#16
Nilson T Poppi, Luís H W Gowdak, Luciana O C Dourado, Eduardo L Adam, Thiago N P Leite, Bruno M Mioto, José E Krieger, Luiz A M César, Alexandre C Pereira
BACKGROUND: The predictors of cardiovascular events in patients with chronic refractory angina are limited. High-sensitivity cardiac troponin T (hs-cTnT) assays are biomarkers that may be used to determine the prognosis of patients with stable coronary artery disease. HYPOTHESIS: Hs-cTnT is a predictor of death and nonfatal myocardial infarction (MI) in patients with refractory angina. METHODS: We prospectively enrolled 117 consecutive patients in this study...
October 18, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27754036/os-13-02-association-between-uric-acid-metabolic-variables-and-arterial-stiffness-in-the-early-phase-of-hypertension
#17
Francesca Saladini, Elisabetta Benetti, Claudio Fania, Lucio Mos, Raffaella Garbelotto, Andrea Mazzer, Edoardo Casiglia, Paolo Palatini
OBJECTIVE: High serum uric acid (SUA) is often associated with the metabolic syndrome and is a risk factor for cardiovascular disease. Whether high SUA is associated with arterial stiffness in the early stage of hypertension is not well known. DESIGN AND METHOD: We addressed this issue in 340 non-diabetic subjects from the HARVEST study (73% males) with a mean age of 31 ± 8 years and a mean blood pressure (BP) of 145 ± 11/92 ± 6 mmHg. Patients were divided into SUA tertiles (T1: 1...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27752355/cardiac-involvement-in-adult-and-juvenile-idiopathic-inflammatory-myopathies
#18
Thomas Schwartz, Louise Pyndt Diederichsen, Ingrid E Lundberg, Ivar Sjaastad, Helga Sanner
Idiopathic inflammatory myopathies (IIM) include the main subgroups polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and juvenile DM (JDM). The mentioned subgroups are characterised by inflammation of skeletal muscles leading to muscle weakness and other organs can also be affected as well. Even though clinically significant heart involvement is uncommon, heart disease is one of the major causes of death in IIM. Recent studies show an increased prevalence of traditional cardiovascular risk factors in JDM and DM/PM, which need attention...
2016: RMD Open
https://www.readbyqxmd.com/read/27743576/effect-of-heart-rate-and-use-of-beta-blockers-on-mortality-after-heart-transplantation
#19
Agnieszka Ciarka, Lars H Lund, Johan Van Cleemput, Gabor Voros, Walter Droogne, Johan Vanhaecke
Heart transplantation (HT) recipients may have tachycardia secondary to cardiac denervation. As higher heart rate predicts worse outcomes in cardiovascular disease, we hypothesized that tachycardia and nonuse of β blockers are associated with increased mortality after HT. All patients who underwent HT at our institution from 1987 to 2010 were included. The association of heart rate 3 months after HT and β-blocker use during follow-up to mortality was assessed using Kaplan-Meier and multivariate Cox proportional hazards regression analyses adjusting for clinically relevant baseline variables...
September 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27741306/diabetic-cardiovascular-autonomic-neuropathy-predicts-recurrent-cardiovascular-diseases-in-patients-with-type-2-diabetes
#20
Seon-Ah Cha, Jae-Seung Yun, Tae-Seok Lim, Kyoungil Min, Ki-Ho Song, Ki-Dong Yoo, Yong-Moon Park, Yu-Bae Ahn, Seung-Hyun Ko
Cardiovascular autonomic neuropathy (CAN) is a risk factor for cardiovascular disease (CVD) and mortality in patients with type 2 diabetes. This study evaluated the relationship between CAN and recurrent CVD in type 2 diabetes. A total of 206 patients with type 2 diabetes who had a history of CVD within 3 years of enrollment were consecutively recruited from January 2001 to December 2009 and followed-up until December 2015. Cardiovascular autonomic function tests were performed using the following heart rate variability parameters: expiration-to-inspiration ratio, response to Valsalva maneuver and standing...
2016: PloS One
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