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https://www.readbyqxmd.com/read/28210957/forced-treadmill-exercise-prevents-spatial-memory-deficits-in-aged-rats-probably-through-the-activation-of-na-k-atpase-in-the-hippocampus
#1
Cláudia Vanzella, Eduardo Farias Sanches, Felipe Kawa Odorcyk, Fabrício Nicola, Janaína Kolling, Aline Longoni, Tiago Marcon Dos Santos, Angela Terezinha de Souza Wyse, Carlos Alexandre Netto
Regular physical activity has shown to improve the quality of life and to prevent age-related memory deficits. Memory processing requires proper regulation of several enzymes such as sodium-potassium adenosine triphosphatase (Na(+), K(+)-ATPase) and acetylcholinesterase (AChE), which have a pivotal role in neuronal transmission. The present study investigated the effects of a treadmill running protocol in young (3 months), mature (6 months) and aged (22 months) Wistar rats, on: (a) cognitive function, as assessed in the Water maze spatial tasks; (b) Na(+), K(+)-ATPase and AChE activities in the hippocampus following cognitive training alone or treadmill running combined with cognitive training...
February 16, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28207880/skeletal-muscle-metabolic-adaptations-to-endurance-exercise-training-are-attainable-in-mice-with-simvastatin-treatment
#2
William M Southern, Anna S Nichenko, Daniel D Shill, Corey C Spencer, Nathan T Jenkins, Kevin K McCully, Jarrod A Call
We tested the hypothesis that a 6-week regimen of simvastatin would attenuate skeletal muscle adaptation to low-intensity exercise. Male C57BL/6J wildtype mice were subjected to 6-weeks of voluntary wheel running or normal cage activities with or without simvastatin treatment (20 mg/kg/d, n = 7-8 per group). Adaptations in in vivo fatigue resistance were determined by a treadmill running test, and by ankle plantarflexor contractile assessment. The tibialis anterior, gastrocnemius, and plantaris muscles were evaluated for exercised-induced mitochondrial adaptations (i...
2017: PloS One
https://www.readbyqxmd.com/read/28207317/effects-of-sensor-position-on-kinematic-data-obtained-with-an-inertial-sensor-system-during-gait-analysis-of-trotting-horses
#3
Valerie J Moorman, David D Frisbie, Christopher E Kawcak, C Wayne McIlwraith
OBJECTIVE To determine the effects of altering location of right forelimb and pelvic sensors on kinematic data obtained with a commonly used inertial sensor system during gait analysis of trotting horses. DESIGN Experimental study. ANIMALS 12 horses with mild to moderate lameness of at least 1 hind limb, with or without lameness of the forelimbs. PROCEDURES All horses were examined while trotting on a high-speed treadmill. The right forelimb sensor was tested at 3 anatomic locations in random order: dorsal midline and 2 cm medial and lateral to that midline...
March 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28197892/the-effect-of-acute-aerobic-exercise-on-hemostasis-in-obstructive-sleep-apnea
#4
Ryan A Martin, Courtney Strosnider, Gabrielle Giersch, Christopher J Womack, Trent A Hargens
PURPOSE: Individuals with obstructive sleep apnea (OSA) have an altered hemostatic balance; however, the exercise response is less described. The purpose of this study is to determine the hemostatic response after acute aerobic exercise in obstructive sleep apnea. METHODS: Eighteen males (nine OSA vs. nine controls) were recruited from the university and local community. Individuals with evidence of cardiovascular, pulmonary, or metabolic disease were excluded. An apnea-hypopnea index (AHI) of >5 was a criterion for OSA...
February 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28195978/lack-of-influence-of-muscular-performance-parameters-on-spatio-temporal-adaptations-with-increased-running-velocity
#5
Luis E Roche-Seruendo, Felipe García-Pinillos, Joana Haicaguerre, Ana V Bataller-Cervero, Víctor M Soto-Hermoso, Pedro Á Latorre-Román
This study aimed to analyse the influence of muscular performance parameters on spatio-temporal gait characteristics during running when gradually increasing speed. 51 recreationally trained male endurance runners (age: 28 ± 8 years) voluntarily participated in this study. Subjects performed a battery of jumping tests (squat jump, countermovement jump, and 20 cm drop jump), and after that, the subjects performed an incremental running test (10 to 20 km/h) on a motorized treadmill. Spatio-temporal parameters were measured using the OptoGait system...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28195842/relationship-between-walking-capacity-and-ambulatory-blood-pressure-in-patients-with-intermittent-claudication
#6
Aluísio H R A Lima, Marcel Chehuen, Gabriel G Cucato, Antônio H G Soares, Christopher D Askew, João P A S Barbosa, Crivaldo C Gomes, Nelson Wolosker, Claudia L M Forjaz, Raphael M Ritti-Dias
OBJECTIVE: Patients with intermittent claudication (IC) often have high blood pressure (BP), which increases their cardiovascular risk. However, whether walking capacity is associated with BP levels in patients with IC remains unknown. Therefore, this study was designed to investigate whether the total walking distance is associated with ambulatory BP in patients with IC. PARTICIPANTS AND METHODS: This was a cross-sectional study of 75 patients with IC (58 men; 17 women)...
February 13, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28185659/change-in-maximal-exercise-capacity-is-associated-with-survival-in-men-and-women
#7
Clinton A Brawner, Mouaz H Al-Mallah, Jonathan K Ehrman, Waqas T Qureshi, Michael J Blaha, Steven J Keteyian
OBJECTIVE: To describe the relationship between change in maximal exercise capacity (MEC) over time and risk of all-cause mortality separately in men and women. PATIENTS AND METHODS: Consecutive patients (n=10,854; mean ± SD age, 54±11 years; 43% women; 30% nonwhite) who completed 2 physician-referred exercise tests between January 2, 1991, and May 28, 2009, were identified from the Henry Ford Exercise Testing (FIT) Project. The MEC was quantified in metabolic equivalents of task (METs) calculated from peak workload on a treadmill and adjusted to the equivalent for a 50-year-old man...
February 6, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28177746/preliminary-safety-analysis-of-high-intensity-interval-training-hiit-in-persons-with-chronic-stroke
#8
Daniel L Carl, Pierce Boyne, Bradley Rockwell, Myron Gerson, Jane Khoury, Brett Kissela, Kari Dunning
The purpose of this study was to assess safety via electrocardiographic (ECG), blood pressure (BP), heart rate (HR), and orthopedic responses to 3 different high-intensity interval training (HIIT) protocols in persons with stroke. Eighteen participants (10 male; 61.9 + 8.3 years of age; 5.8 + 4.2 years poststroke) completed a symptom-limited graded exercise test (GXT) with ECG monitoring to screen for eligibility and determine HR peak. The 3 HIIT protocols involved repeated 30 s bursts of treadmill walking at maximum speed alternated with rest periods of 30 s (P30), 1 min (P60), or 2 min (P120)...
November 21, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28177724/dose-dependent-decrease-in-mortality-with-no-cognitive-or-muscle-function-improvements-due-to-dietary-egcg-supplementation-in-aged-mice
#9
Brandt D Pence, Tushar K Bhattacharya, Pul Park, Jennifer L Rytych, Jacob M Allen, Yi Sun, Robert H McCusker, Keith W Kelley, Rodney W Johnson, Justin S Rhodes, Jeffrey A Woods
We have previously shown that a diet containing epigallocatechin gallate (EGCG) and beta-alanine is not effective in improving either cognitive or muscle function in aged (18 month) mice (Gibbons et al. Behav Brain Res 2014, Pence et al. Appl Physiol Nutr Metab 2016). However, this diet reduced oxidative stress in the brain, and previous studies using longer-term interventions and other doses have documented beneficial effects in cognitive and muscle function, especially with EGCG. Here we hypothesized that a different dose of EGCG or longer feeding period would be more efficacious in improving cognition...
January 5, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28177723/fish-oil-and-treadmill-exercise-have-age-dependent-effects-on-episodic-memory-and-oxidative-state-of-the-hippocampus
#10
Patrícia Fortes Cavalcanti de Macêdo, Janatar Stella Vasconcelos de Melo, Laís Alves Ribeiro Costa, Glauber Rudá Feitoza Braz, Shirley M de Sousa, Cláudia J Lagranha, Manuella Batista-de-Oliveira Hornsby
There is a growing interest to better understand how lifestyle choices can improve memory functions. Treadmill exercise (Ex) and long-chain n-3 polyunsaturated fatty acids (PUFAs) found in fish oil (Fo) are able to stimulate hippocampal antioxidant defenses and improve memory. The aim was to test whether (Fo) and (Ex) can improve rat's performance on memory tasks and optimize hippocampal antioxidant state in an age-dependent manner. Therefore, young and adult rats were exercised and received (Fo) during four weeks...
January 9, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28176415/visceral-fat-is-associated-with-the-racial-differences-in-liver-fat-between-black-and-white-adolescent-boys-with-obesity
#11
SoJung Lee, Jennifer L Kuk
OBJECTIVE: We examined whether racial differences in liver fat are associated with the differences in abdominal fat distribution or cardiorespiratory fitness (CRF). METHODS: Participants included 57 black and white obese boys (12-18 years). Total and abdominal fat was measured by dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging, respectively. CRF was measured using a maximal graded treadmill test with the use of standard open-circuit spirometry techniques until volitional fatigue...
February 8, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28174453/effects-of-inclined-treadmill-walking-training-with-rhythmic-auditory-stimulation-on-balance-and-gait-in-stroke-patients
#12
Sung Kyeung Yoon, Soon Hee Kang
[Purpose] The purpose of this study was to determine if an inclined treadmill with rhythmic auditory stimulation gait training can improve balance and gait ability in stroke patients. [Subjects and Methods] Thirty participants were randomly divided into three groups: inclined treadmill with rhythmic auditory stimulation training group (n=10), inclined treadmill training group (n=10), and treadmill training group (n=10). For all groups, the training was conducted for 4 weeks, 30 minutes per session, 5 times per week...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28174445/treadmill-training-with-partial-body-weight-support-after-anterior-cruciate-ligament-reconstruction-a-randomized-controlled-trial
#13
Yuan Luo, Weizhong Shen, Zhong Jiang, Jiao Sha
[Purpose] To compare the effects of treadmill training with partial body weight support (TTPBWS) and conventional physical therapy (PT) on subjects with anterior cruciate ligament reconstructions. [Subjects and Methods] A total of 40 subjects were randomly allocated to either a treatment group or a control group. Subjects received either treadmill training with partial body weight support (treatment group) or conventional physical therapy (control group). The circumferences of the lower extremities, Holden classifications, 10-meter walking times and the International Knee Documentation Committee (IKDC) scores were compared at 12 and 24 weeks post-operation...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28166650/the-effects-of-exercise-load-during-development-on-oxidative-stress-levels-and-antioxidant-potential-in-adulthood
#14
S Lee, J Hashimoto, T Suzuki, A Satoh
The objective of this study was to elucidate the impact of physical activity during the growth period as well as on oxidative stress and antioxidative potential in adulthood. The experimental animals used were four-week old male Wistar rats, which were randomly divided into three groups. The exercise loads were as follows: control (CON), treadmill exercise (TE), and jumping exercise (JE). The exercise was performed at the same time of day, at a frequency of five days per week, for eight weeks. Derivatives of reactive oxygen metabolites (d-ROSs) and biological antioxidant potential (BAP) were measured during periods of rest prior to commencement of the experiment and after the experiment...
February 6, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28166185/heat-exposure-and-hypohydration-exacerbate-physiological-strain-during-load-carrying
#15
Elizabeth L Adams, Douglas J Casa, Robert A Huggins, Julie K DeMartini, Rebecca L Stearns, Rachel M Kennedy, Lindsay J DiStefano, Lawrence E Armstrong, Carl M Maresh
Heat exposure and hypohydration induce physiological and psychological strain during exercise; however, it is unknown if the separate effects of heat exposure and hypohydration are synergistic when co-occurring during loaded exercise. This study compared separate and combined effects of heat exposure and hypohydration on physiological strain, mood state, and visual vigilance during loaded exercise. Twelve males (mean±SD; age, 20±2 years; body mass, 74.0±8.2 kg; maximal oxygen uptake, 57.0±6.0 mLkg-1min-1) completed 4 trials under the following conditions: euhydrated temperate (EUT), hypohydrated temperate (HYT), euhydrated hot (EUH), and hypohydrated hot (HYH)...
February 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28166116/cerebral-blood-flow-responses-to-aquatic-treadmill-exercise
#16
Rhodri Parfitt, Marianne Y Hensman, Samuel J E Lucas
INTRODUCTION: Aquatic treadmills are used as a rehabilitation method for conditions such as spinal cord injury, osteoarthritis and stroke, and can facilitate an earlier return to exercise training for athletes. However, their effect on cerebral blood flow (CBF) responses has not been examined. We tested the hypothesis that aquatic treadmill exercise would augment CBF and lower heart rate compared to land-based treadmill exercise. METHODS: Eleven participants completed incremental exercise (crossover design) starting from walking pace [4 km/h, immersed to iliac crest (aquatic), 6 km/h (land)] and increasing 1 km/h every 2 min up to 10 km/h for aquatic (maximum belt speed) or 12 km/h for land...
February 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28163315/effects-of-topical-capsaicin-combined-with-moderate-exercise-on-insulin-resistance-body-weight-and-oxidative-stress-in-hypoestrogenic-obese-rats
#17
J M L Medina-Contreras, J Colado-Velázquez, N L Gómez-Viquez, P Mailloux-Salinas, I Perez-Torres, A Aranda-Fraustro, K Carvajal, G Bravo
BACKGROUND: Hypoestrogenic women are one of the most vulnerable groups for the development of obesity and its complications. Capsaicin and exercise have demonstrated to reduce body weight and to improve insulin sensitivity in different animal models, but it is unknown whether their combination could be useful in hypoestrogenic obese females. METHODS: We investigated whether topical capsaicin, exercise or their combination had better therapeutic effects in an obesity-hypoestrogenism model...
February 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28161106/dynamic-assessment-of-center-of-pressure-measurements-from-an-instrumented-amti-treadmill-with-controlled-precision
#18
Emma Fortune, Jeremy Crenshaw, Vipul Lugade, Kenton R Kaufman
With the increasing use of instrumented force treadmills in biomechanical research, it is imperative that the validity of center of pressure (COP) measurements is established. The study aims were to compare an instrumented treadmill's static-belt COP accuracy to that of a floor-embedded platform, develop a novel method to quantify dynamic-belt COP accuracy with controlled precision and perform an initial investigation of how dynamic COP accuracy changes with weight and velocity. Static COP accuracy was assessed by applying a force while moving a rigid rod in a circular clockwise motion at nine positions of interest on the two treadmill and two ground-embedded force plates...
February 1, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28161031/fmri-activity-during-associative-encoding-is-correlated-with-cardiorespiratory-fitness-and-source-memory-performance-in-older-adults
#19
Scott M Hayes, Jasmeet P Hayes, Victoria J Williams, Huiting Liu, Mieke Verfaellie
Older adults (OA), relative to young adults (YA), exhibit age-related alterations in functional Magnetic Resonance Imaging (fMRI) activity during associative encoding, which contributes to deficits in source memory. Yet, there are remarkable individual differences in brain health and memory performance among OA. Cardiorespiratory fitness (CRF) is one individual difference factor that may attenuate brain aging, and thereby contribute to enhanced source memory in OA. To examine this possibility, 26 OA and 31 YA completed a treadmill-based exercise test to evaluate CRF (peak VO2) and fMRI to examine brain activation during a face-name associative encoding task...
January 12, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28158197/rehabilitation-in-progressive-supranuclear-palsy-effectiveness-of-two-multidisciplinary-treatments
#20
Ilaria Clerici, Davide Ferrazzoli, Roberto Maestri, Fabiola Bossio, Ilaria Zivi, Margherita Canesi, Gianni Pezzoli, Giuseppe Frazzitta
BACKGROUND: to date, there are no medical or surgical treatments for progressive supranuclear palsy (PSP). It is possible to speculate that patients with PSP could benefit from rehabilitative treatments designed for Parkinson's disease, including the use of robot-assisted walking training. OBJECTIVE: to evaluate whether the use of the robotic device Lokomat® is superior in PSP patients to the use of treadmill with visual cues and auditory feedbacks (treadmill-plus) in the context of an aerobic, multidisciplinary, intensive, motor-cognitive and goal-based rehabilitation treatment (MIRT) conceived for Parkinsonian patients...
2017: PloS One
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