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https://www.readbyqxmd.com/read/28453295/postinjury-exercise-and-platelet-rich-plasma-therapies-improve-skeletal-muscle-healing-in-rats-but-are-not-synergistic-when-combined
#1
Paola Contreras-Muñoz, Joan Ramon Torrella, Xavier Serres, David Rizo-Roca, Meritxell De la Varga, Ginés Viscor, Vicente Martínez-Ibáñez, José Luis Peiró, Tero A H Järvinen, Gil Rodas, Mario Marotta
BACKGROUND: Skeletal muscle injuries are the most common sports-related injury and a major concern in sports medicine. The effect of platelet-rich plasma (PRP) injections on muscle healing is still poorly understood, and current data are inconclusive. PURPOSE: To evaluate the effects of an ultrasound-guided intramuscular PRP injection, administered 24 hours after injury, and/or posttraumatic daily exercise training for 2 weeks on skeletal muscle healing in a recently established rat model of skeletal muscle injury that highly mimics the muscle trauma seen in human athletes...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28449270/strong-association-between-cardiorespiratory-fitness-and-serum-lipoprotein-subclass-pattern-in-prepubertal-healthy-children
#2
Geir Kåre Resaland, Tarja Rajalahti, Eivind Aadland, Olav Martin Kvalheim
AIM: To reveal the lipoprotein subclass pattern associated to cardiorespiratory fitness (CRF) in healthy children. METHODS: Serum concentrations of lipoprotein subclasses and concentrations and average particle size of their main classes were quantified in 94 ethnic Norwegian children using high performance liquid chromatography (HPLC). Twenty-four lipoprotein features were used as input to multivariate regression analysis with CRF measured either as peak oxygen consumption (VO2peak) using a continuous treadmill protocol or indirectly by the 10 minute Andersen intermittent running field test...
April 27, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28446953/neuroprotective-effects-of-exercise-on-brain-edema-and-neurological-movement-disorders-following-the-cerebral-ischemia-and-reperfusion-in-rats
#3
Nabi Shamsaei, Soheila Erfani, Masoud Fereidoni, Ali Shahbazi
INTRODUCTION: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders following the cerebral ischemia and reperfusion in rats was investigated. METHODS: Twenty-one adult male wistar rats (weighing 260-300 g) were randomly divided into three groups: sham operated, exercise plus ischemia, and ischemia group (7 rats per group)...
January 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/28440910/subacute-pyridostigmine-exposure-increases-heart-rate-recovery-and-cardiac-parasympathetic-tone-in-rats
#4
Manushree Bharadwaj, Carey Pope, Michael Davis, Stuart Katz, Christian Cook, Lara Maxwell
Heart rate recovery (HRR) describes the rapid deceleration of heart rate after strenuous exercise and is an indicator of parasympathetic tone. A reduction in parasympathetic tone occurs in patients with congestive heart failure, resulting in prolonged HRR. Acetylcholinesterase inhibitors, such as pyridostigmine, can enhance parasympathetic tone by increasing cholinergic input to the heart. The objective of this study was to develop a rodent model of HRR to test the hypothesis that subacute pyridostigmine administration decreases cholinesterase activity and accelerates HRR in rats...
April 25, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28439212/effect-of-thyme-extract-supplementation-on-lipid-peroxidation-antioxidant-capacity-pgc-1%C3%AE-content-and-endurance-exercise-performance-in-rats
#5
Mostafa Khani, Pezhman Motamedi, Mohammad Reza Dehkhoda, Saeed Dabagh Nikukheslat, Pouran Karimi
BACKGROUND: Athletes have a large extent of oxidant agent production. In the current study, we aimed to determine the influence of thyme extract on the endurance exercise performance, mitochondrial biogenesis, and antioxidant status in rats. METHODS: Twenty male Wistar rats were randomly divided into two groups receiving either normal drinking water (non-supplemented group, n = 10) or thyme extract, 400 mg/kg, (supplemented group, n = 10). Rats in both groups were subjected to endurance treadmill training (27 m/min, 10% grade, 60 min, and 5 days/week for 8 weeks)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28438166/adjacent-regenerative-peripheral-nerve-interfaces-produce-phase-antagonist-signals-during-voluntary-walking-in-rats
#6
Daniel Ursu, Andrej Nedic, Melanie Urbanchek, Paul Cederna, R Brent Gillespie
BACKGROUND: Regenerative Peripheral Nerve Interfaces (RPNIs) are neurotized muscle grafts intended to produce electromyographic signals suitable for motorized prosthesis control. Two RPNIs producing independent agonist/antagonist signals are required for each control axis; however, it is unknown whether signals from adjacent RPNIs are independent. The purpose of this work was to determine signaling characteristics from two adjacent RPNIs, the first neurotized by a foot dorsi-flexor nerve and the second neurotized by a foot plantar-flexor nerve in a rodent model...
April 24, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28435743/effects-of-overground-locomotor-training-on-the-ventilatory-response-to-volitional-treadmill-walking-in-individuals-with-incomplete-spinal-cord-injury-a-pilot-study
#7
Gino S Panza, Andrew A Guccione, Lisa M Chin, Jared M Gollie, Jeffery E Herrick, John P Collins
INTRODUCTION: Although there has been substantial emphasis on the neuromuscular and cardiovascular adaptations following rehabilitation, pulmonary adaptations in individuals with incomplete SCI (iSCI) in response to locomotor training have been less frequently studied. In healthy individuals, effective transition from rest to work is accomplished by a hyperpneic response, which exhibits an exponential curve with three phases. However, the degree to which our current understanding of exercise hyperpnea can be applied to individuals with iSCI is unknown...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28433867/validity-and-repeatability-of-inertial-measurement-units-for-measuring-gait-parameters
#8
Edward P Washabaugh, Tarun Kalyanaraman, Peter G Adamczyk, Edward S Claflin, Chandramouli Krishnan
Inertial measurement units (IMUs) are small wearable sensors that have tremendous potential to be applied to clinical gait analysis. They allow objective evaluation of gait and movement disorders outside the clinic and research laboratory, and permit evaluation on large numbers of steps. However, repeatability and validity data of these systems are sparse for gait metrics. The purpose of this study was to determine the validity and between-day repeatability of spatiotemporal metrics (gait speed, stance percent, swing percent, gait cycle time, stride length, cadence, and step duration) as measured with the APDM Opal IMUs and Mobility Lab system...
April 12, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28431220/contribution-of-ankle-foot-orthosis-moment-in-regulating-ankle-and-knee-motions-during-gait-in-individuals-post-stroke
#9
Toshiki Kobayashi, Michael S Orendurff, Madeline L Singer, Fan Gao, K Bo Foreman
BACKGROUND: Ankle-foot orthosis moment resisting plantarflexion has systematic effects on ankle and knee joint motion in individuals post-stroke. However, it is not known how much ankle-foot orthosis moment is generated to regulate their motion. The aim of this study was to quantify the contribution of an articulated ankle-foot orthosis moment to regulate ankle and knee joint motion during gait in individuals post-stroke. METHODS: Gait data were collected from 10 individuals post-stroke using a Bertec split-belt instrumented treadmill and a Vicon 3-dimensional motion analysis system...
April 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28430704/functional-effects-of-treadmill-based-gait-training-at-faster-speeds-in-stroke-survivors-a-prospective-single-group-study
#10
Roghayeh Mohammadi, Navid Ershad, Marziyeh Rezayinejad, Elham Fatemi, Chetan P Phadke
To examine the functional effects of walking retraining at faster than self-selected speed (SSS). Ten individuals with chronic stroke participated in a 4-week training over a treadmill at walking speeds 40% faster than SSS, three times per week, 30 min/session. Outcome measures assessed before, after, and 2 months after the end of intervention were the Timed Up and Go, the 6-Minute Walk, the 10-Meter Walk test, the Modified Ashworth Scale, SSS, and fastest comfortable speed. After 4 weeks of training, all outcome measures showed clinically meaningful and statistically significant improvements (P<0...
April 20, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28430546/overall-preference-of-running-shoes-can-be-predicted-by-suitable-perception-factors-using-a-multiple-regression-model
#11
Cheryl Sihui Tay, Thorsten Sterzing, Chen Yen Lim, Rui Ding, Pui Wah Kong
OBJECTIVE: This study examined (a) the strength of four individual footwear perception factors to influence the overall preference of running shoes and (b) whether these perception factors satisfied the nonmulticollinear assumption in a regression model. BACKGROUND: Running footwear must fulfill multiple functional criteria to satisfy its potential users. Footwear perception factors, such as fit and cushioning, are commonly used to guide shoe design and development, but it is unclear whether running-footwear users are able to differentiate one factor from another...
May 2017: Human Factors
https://www.readbyqxmd.com/read/28429698/coronary-microvascular-dysfunction-equivalent-to-left-main-coronary-artery-disease
#12
Cafer Panç, Mehmet Kocaağa, Onur Erdoğan, Remzi Sarıkaya, Sabahattin Umman
Coronary microvascular dysfunction, also known as cardiac syndrome X, is a clinical syndrome presenting with typical angina and evidence of myocardial ischemia in the absence of flow-limiting stenosis on coronary angiography. Of patients undergoing coronary angiography due to suspected myocardial ischemia, 50% are found to have normal or near-normal coronary arteries. Described in this case report is a patient who developed hypotension and ST segment depressions during treadmill exercise test. Left main coronary artery or multivessel disease was suspected...
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28428145/prior-treadmill-exercise-promotes-resilience-to-vicarious-trauma-in-rats
#13
Camila Kochi, Hesong Liu, Safiyya Zaidi, Fatin Atrooz, Phoebe Dantoin, Samina Salim
BACKGROUND: Post-traumatic stress disorder (PTSD) is a serious psychological condition, which can develop both from physically experiencing and also from witnessing traumatic events. There is evidence that physical exercise can have a positive impact on the symptoms of PTSD. Relevant to this, in our previous pre-clinical work, beneficial effects of treadmill exercise were reported on PTSD-like behaviors in a social defeat paradigm, a rat model of direct physical trauma. However, the role of exercise on vicariously acquired PTSD-like phenotype was not examined...
April 17, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28418696/eccentric-exercise-kinesiology-tape-and-balance-in-healthy-men
#14
Simona Hosp, Ramona Folie, Robert Csapo, Michael Hasler, Werner Nachbauer
CONTEXT:   Deficits in balance have been identified as a possible risk factor for knee injuries in athletes. Despite a lack of evidence for its effectiveness, kinesiology tape (KT) is widely used to prevent knee injuries. OBJECTIVE:   To investigate the influence of KT at the knee joint on balance ability in healthy men after eccentric exercise. DESIGN:   Crossover study. SETTING:   University laboratory. PATIENTS OR OTHER PARTICIPANTS:   Twelve young men with no history of lower limb injury volunteered for the study (age = 23...
April 18, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28416899/the-efficacy-of-a-discontinuous-graded-exercise-test-in-measuring-peak-oxygen-uptake-in-children-aged-8-to-10-years
#15
D Lambrick, J Jakeman, R Grigg, S Kaufmann, J Faulkner
As children's natural activity patterns are highly intermittent in nature, and characterised by rapid changes from rest to vigorous physical activity, discontinuous exercise tests may be considered ecologically valid for this population group. This study compared the peak physiological responses from a discontinuous and continuous graded exercise test (GXT_D, GXT_C, respectively) during treadmill exercise in children. Twenty-one healthy children (9.6 ± 0.6 y) completed GXT_D and GXT_C in a randomised order, separated by 72-hours...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28414015/effects-of-depression-metabolic-syndrome-and-cardiorespiratory-fitness-on-mortality-results-from-the-cooper-center-longitudinal-study
#16
C D Rethorst, D Leonard, C E Barlow, B L Willis, M H Trivedi, L F DeFina
BACKGROUND: Depression and metabolic syndrome (MetS) are frequently comorbid disorders that are independently associated with premature mortality. Conversely, cardiorespiratory fitness (CRF) is associated with reduced mortality risk. These factors may interact to impact mortality; however, their effects have not been assessed concurrently. This analysis assessed the mortality risk of comorbid depression/MetS and the effect of CRF on mortality in those with depression/MetS. METHODS: Prospective study of 47 702 adults in the Cooper Center Longitudinal Study...
April 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28410868/quantifying-cardiorespiratory-responses-resulting-from-speed-and-slope-increments-during-motorized-treadmill-propulsion-among-manual-wheelchair-users
#17
Cindy Gauthier, Murielle Grangeon, Ludivine Ananos, Rachel Brosseau, Dany H Gagnon
BACKGROUND: Cardiorespiratory fitness assessment and training among manual wheelchair (MW) users are predominantly done with an arm-crank ergometer. However, arm-crank ergometer biomechanics differ substantially from MW propulsion biomechanics. This study aimed to quantify cardiorespiratory responses resulting from speed and slope increments during MW propulsion on a motorized treadmill and to calculate a predictive equation based on speed and slope for estimating peak oxygen uptake (VO2peak) in MW users...
April 11, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28410594/physical-human-robot-interaction-of-an-active-pelvis-orthosis-toward-ergonomic-assessment-of-wearable-robots
#18
Nicolò d'Elia, Federica Vanetti, Marco Cempini, Guido Pasquini, Andrea Parri, Marco Rabuffetti, Maurizio Ferrarin, Raffaele Molino Lova, Nicola Vitiello
BACKGROUND: In human-centered robotics, exoskeletons are becoming relevant for addressing needs in the healthcare and industrial domains. Owing to their close interaction with the user, the safety and ergonomics of these systems are critical design features that require systematic evaluation methodologies. Proper transfer of mechanical power requires optimal tuning of the kinematic coupling between the robotic and anatomical joint rotation axes. We present the methods and results of an experimental evaluation of the physical interaction with an active pelvis orthosis (APO)...
April 14, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28409509/fitness-can-be-a-determinant-of-arterial-stiffness-in-healthy-adult-men-a-cross-sectional-study
#19
Jin-Wook Chung, Mi-Lyang Kim, Youngsoo Jin, Yonghwan Kim, Jeeyoung Hong
BACKGROUND: Fitness is known to influence arterial stiffness. This study aimed to assess differences in cardiorespiratory endurance, muscular strength, and flexibility according to arterial stiffness, based on sex and age. METHODS: We enrolled 1,590 healthy adults (men: 1,242, women: 348) who were free of metabolic syndrome. We measured cardiorespiratory endurance in an exercise stress test on a treadmill, muscular strength by a grip test, and flexibility by upper body forward-bends from a standing position...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28405132/antianginal-efficacy-and-tolerability-of-ranolazine-as-an-add-on-drug-to-concomitant-medications-primarily-metoprolol-in-chronic-stable-angina-patients-a-prospective-open-label-study
#20
Anant Mahaveer Khot, H V Anuradha, V S Prakash, M C Shivamurathy
OBJECTIVE: To evaluate the efficacy and tolerability of ranolazine as an add-on drug in chronic stable angina patients and the impact of ranolazine on the quality of life in chronic stable angina patients receiving other antianginal medications. MATERIALS AND METHODS: It was a prospective, open-label, hospital-based study involving 144 patients with chronic stable angina. First group received either metoprolol 12.5 or 25 mg/day or other antianginal medications; if the symptoms persist, the dose of metoprolol was increased to 50 mg/day, and to the second group, ranolazine 500 mg BD or 1 g OD was added along with metoprolol or others if the anginal attacks were not subsiding...
January 2017: Journal of Pharmacology & Pharmacotherapeutics
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