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Claudio Poggio, Matteo Viola, Maria Mirando, Marco Chiesa, Riccardo Beltrami, Marco Colombo
Background: Acidic beverages, such as soft drinks (orange juice and cola), can produce erosion of resin composites. The aim of this in vitro study was to evaluate the effect of immersion in acidic drink on the Vickers microhardness (VK) of different esthetic restorative materials (one nanohybrid Ormocer-based composite, one nanoceramic composite, one nanofilled composite, and one microfilled hybrid composite). Materials and Methods: In this in vitro study, thirty specimens of each esthetic restorative material were divided into three subgroups ( n = 10): specimens of group 1 were used as control, specimens of group 2 were immersed in 50 ml of acidic drink for 1 day, specimens of group 3 were immersed in 50 ml of acidic drink for 7 days...
May 2018: Dental Research Journal
John Michael Madonna
The following is a discussion of the issue of religious faith on the part of the analyst, in terms of how it comes to bear on the psychological treatment of patients who have faith and some who do not. A consideration, and refutation, of Freud's position on religion and his belief in a supreme being as an illusion will be conducted, along with subsequent analytic thinking on this matter. The author's personal experience will be described, and how he is affirmed and sometimes challenged by the various clinical situations in which he finds himself...
June 2018: Journal of Pastoral Care & Counseling: JPCC
Shaowei Ding, Suprem R Das, Benjamin J Brownlee, Kshama Parate, Taylor M Davis, Loreen R Stromberg, Edward K L Chan, Joseph Katz, Brian D Iverson, Jonathan C Claussen
Vertically aligned carbon nanotube array (VANTA) coatings have recently garnered significant attention due in part to their unique material properties including light absorption, chemical inertness, and electrical conductivity. Herein we report the first use of VANTAs grown via chemical vapor deposition in a 2D interdigitated electrode (IDE) footprint with a high height-to-width aspect ratio (3:1 or 75:25 µm). The VANTA-IDEs were functionalized with an antibody (Ab) specific to the human cancerous inhibitor PP2A (CIP2A)-an oncoprotein that is associated with a variety of malignancies such as oral, breast, and multiple myeloma cancers...
April 8, 2018: Biosensors & Bioelectronics
Lynne Dawkins, Sharon Cox, Maciej Goniewicz, Hayden McRobbie, Catherine Kimber, Mira Doig, Leon Kośmider
AIMS: To compare the effects of i) high versus low nicotine concentration e-liquid, ii) fixed versus adjustable power and iii) the interaction between the two on: a) vaping behaviour, b) subjective effects, c) nicotine intake, and d) exposure to acrolein and formaldehyde in e-cigarette users vaping in their everyday setting. DESIGN: Counterbalanced, repeated measures with four conditions: i) low nicotine (6 mg/mL)/fixed power; ii) low nicotine/adjustable power; iii) high nicotine (18 mg/mL)/fixed power; iv) high nicotine/adjustable power...
June 7, 2018: Addiction
Richard Croker, Darren Smyth, Alex J Walker, Ben Goldacre
OBJECTIVES: Following litigation over pregabalin's second-use medical patent for neuropathic pain, National Health Service (NHS) England was required by the court to instruct general practitioners (GPs) to prescribe the branded form (Lyrica) for pain. Pfizer's patent was found invalid in 2015, a ruling subject to ongoing appeals. If the Supreme Court appeal in February 2018, whose judgement is awaited, is unsuccessful, the NHS can seek to reclaim excess prescribing costs. We set out to describe the variation in prescribing of pregabalin as branded Lyrica, geographically and over time; to determine how clinicians responded to the NHS England instruction to GPs; and to model excess costs to the NHS attributable to the legal judgements...
June 7, 2018: BMJ Open
M Binnebösel, A Lambertz, K Dejong, U P Neumann
BACKGROUND: The prognosis of colorectal cancer in UICC stage IV has been improved in the last decades by improvements in interdisciplinary treatment. MATERIAL AND METHODS: Treatment strategies for oligometastasized colorectal cancer are developing more and more into an individualized treatment. An overview of the current literature of modern treatment concepts in oligometastasized colorectal cancer UICC stage IV is given. RESULTS: Surgery still has the supreme mandate in resectable colorectal liver metastases, as neoadjuvant and adjuvant treatment strategies to not provide any benefits for these patients...
June 5, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Peivand Bastani, Mahnaz Samadbeik, Rassoul Dinarvand, Sara Kashefian-Naeeini, Soudabeh Vatankhah
BACKGROUND: Iranian health sector encountered many challenges in resource allocation and health service purchasing during the past decades, the aim of this study was to determine the main challenges of the present process of health service purchasing for national policymakers and other developing countries with the same setting. METHODS: It was a qualitative study carried out via the complete content analysis of all relevant national documents from 2007 to 2014...
June 5, 2018: BMC Health Services Research
Ji-Fei Feng, Tian-Fu Liu, Jianlin Shi, Shui-Ying Gao, Rong Cao
A novel dual-emitting Metal-Organic Framework (MOF) based on Zr and Eu, named as UiO-66(Zr&Eu), was built using a clever secondary building units (SBU) based strategy. With the assistance of polymers, the obtained UiO-66(Zr&Eu) was subsequently deposited as thin films that can be utilized as smart thermometer. The UiO-66(Zr&Eu) polymer films can be used for the detection of the temperature change in the temperature range of 237-337 K due to the energy transfer both lanthanide ions (Eu in clusters) and luminescent ligands, and the supreme relative sensitivity reaches to 4...
May 30, 2018: ACS Applied Materials & Interfaces
Chia-Kuang Tsai, Tung-Wei Kao, Jiunn-Tay Lee, Chung-Ching Wang, Chung-Hsing Chou, Chih-Sung Liang, Fu-Chi Yang, Wei-Liang Chen
Dementia is the supreme worldwide burden for welfare and the health care system in the 21st century. The early identification and control of the modifiable risk factors of dementia are important. Global-cognitive health (GCH) metrics, encompassing controllable cardiovascular health (CVH) and non-CVH risk factors of dementia, is a newly developed approach to assess the risk of cognitive impairment. The components of ideal GCH metrics includes better education, non-obesity, normal blood pressure, no smoking, no depression, ideal physical activity, good social integration, normal glycated hemoglobin (HbA1c), and normal hearing...
2018: PloS One
Joshua D Harris
In nonarthritic patients with femoroacetabular impingement syndrome, borderline dysplasia, and symptomatic iliopsoas snapping, arthroscopic iliopsoas fractional lengthening carries a significant risk of postarthroscopic instability. The iliopsoas is a dynamic stabilizer of the anterior hip. Thus, although statistically significant and clinically important improvements in hip function have the potential to be achieved with iliopsoas fractional lengthening, surgeons must be supremely confident in their ability to perform a secure capsular plication, labral preservation (not debridement), comprehensive cam correction, avoidance of intra-abdominal fluid extravasation, release of all iliopsoas tendon bands (if bifid or trifid), and ensure that femoral version is normal or low, neck-shaft angle is not excessively valgus, the dysplasia magnitude is no more than mild, and that there is no excessive soft tissue hypermobility...
June 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
Ge Yang, Yang Fu, Luxiao Yan, Menghua Wang, Hongtao Dong, Qiuming Li
The purpose of this investigation was to explore the combined effects of single nucleotide polymorphisms (SNPs) within LFA-1/ICAM-1/GSK-3β pathway and environmental hazards on susceptibility to Graves' opthalmopathy (GO) among a Chinese Han population. Altogether 305 GO patients and 283 Graves' disease (GD) subjects were recruited. Information relevant to the participants' age, gender, body mass index (BMI), regular physical activity, smoking history, alcohol intake, stressful work environment, stress at work, family history of thyroid disease and 131 I treatment were summarized, and the participants' related SNPs of LFA-1/ICAM-1/GSK-3β were also detected...
May 22, 2018: Experimental Eye Research
Julia Raifman, Ellen Moscoe, S Bryn Austin, Mark L Hatzenbuehler, Sandro Galea
Importance: Recent evidence suggests that state policies affecting sexual minorities are associated with health disparities. Twelve states have laws permitting the denial of services to same-sex couples, and the US Supreme Court is considering whether states can prohibit the denial of services to same-sex couples. Objective: We investigated whether state laws permitting individuals to refuse services to sexual minorities were associated with changes in the proportion of sexual minority adults reporting mental distress...
May 23, 2018: JAMA Psychiatry
Diana Carla Mada, Cristina Gasparik, Alexandra Iulia Irimie, Marius Dan Mada, Diana Dudea, Radu Septimiu Campian
Background and aims: To evaluate the staining effects of two brands of coffee and the bleaching efficiency of two in-office bleaching methods, upon different opacities of a commercial nanocomposite. Methods: Twenty four specimens of each opacity, A3 Dentin, A3 Body and A3 Enamel, were fabricated from Filtek Supreme (3MEspe). The specimens were further divided into two groups (n=12) and were immersed in two coffee solutions (Bio Organic Coffee Bellarom, 100% Arabica, and Iulius Meinl Coffee), for 24 hours...
2018: Clujul Medical (1957)
Chris McKinnon, Dafydd Loughran, Roísín Finn, Madeline Coxwell-Matthewman, Deva Sanjeeva Jeyaretna, Adam P Williams
BACKGROUND: The Supreme Court case of Montgomery vs Lanarkshire Health Board in 2015 was a landmark case for consent practice in the UK which shifted focus from a traditional paternalistic model of consent towards a more patient-centered approach. Widely recognised as the most significant legal judgment on informed consent in the last 30 years, the case was predicted to have a major impact on the everyday practice of surgeons working in the UK National Health Service (NHS). Two years after the legal definition of informed consent was redefined, we carried out an audit of surgical consent practice across the UK to establish the impact of the Montgomery ruling on clinical practice...
May 15, 2018: International Journal of Surgery
Eric A Feldman
This article marks the 30th anniversary of the Supreme Court of New Jersey's Baby M decision by offering a critical analysis of surrogacy policy in the United States. Despite fundamental changes in both science and society since the case was decided, state courts and legislatures remain bitterly divided on the legality of surrogacy. In arguing for a more uniform, permissive legal posture toward surrogacy, the article addresses five central debates in the surrogacy literature. First, should the legal system accommodate those seeking conception through surrogacy, or should it prohibit such arrangements? Second, if surrogacy is permitted, what steps can be taken to minimize the potential exploitation of women who are willing to rent their wombs for income? Third, what criteria should govern the eligibility to serve as a surrogate mother and an intended parent? Fourth, what principle(s) should serve as the basis for determining the parentage of children born through surrogacy? Fifth, is regulatory uniformity in the surrogacy realm desirable? Is it achievable? The article concludes that courts and legislatures should accept the validity of surrogacy contracts, determine parentage according to intent, and identify transparent criteria for the eligibility of both surrogates and intended parents...
March 2018: American Journal of Law & Medicine
Marisa Bartolotta
No abstract text is available yet for this article.
March 2018: American Journal of Law & Medicine
Achmet Ali, Demet Altun, Nukhet Sivrikoz, Mesut Yornuk, Namigar Turgut, İbrahim Özkan Akıncı
Objective: The Supreme™ laryngeal mask airway (SLMA) is a supra glottic airway (SGA) device that is used as an alternative to endotracheal tubes. In the present study, we aimed to compare the use of the SLMA with normal cuff pressure and low cuff pressure, primarily for haemodynamic response. Methods: In the present study, 120 patients diagnosed with hypertension and scheduled for varicose vein or inguinal hernia operation were enrolled and 99 patients finished...
April 2018: Turkish Journal of Anaesthesiology and Reanimation
Robert McMillen
Dr John Thorp presents the clinical conundrum of working in an establishment where his views on abortion, based on his interpretation of Hippocratic and Catholic ethical codes, were not in kilter with those of his department. Others interpret Hippocratic and Christian ethics differently. As Thorp concedes, the oath was not uncontested even in Hippocrates' day, with most Greek thinkers commending abortion, at least prior to viability (US Supreme Court. Roe v. Wade, 410 U.S. 113 1973 Section VI). Perhaps Hippocrates was against inducing abortion, in 500 BC, because of the harm it would do the mother?...
May 4, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Siemon De Nys, Eveline Putzeys, Philippe Vervliet, Adrian Covaci, Imke Boonen, Marc Elskens, Jeroen Vanoirbeek, Lode Godderis, Bart Van Meerbeek, Kirsten L Van Landuyt, Radu Corneliu Duca
There is a growing necessity to acquire more profound knowledge on the quantity of eluates from resin-based dental materials, especially with regard to bisphenol A (BPA). The aim of the present study was to develop a highly sensitive method to characterize the short-term release of BPA in saliva with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), using an extraction step and additional derivatization of BPA with pyridine-3-sulfonyl chloride. Light-cured resin-based composites were incubated at 37 °C in 1 mL artificial saliva, which was refreshed daily for one week...
May 3, 2018: Scientific Reports
Piyali Mitra
The recent spectacular progress in assisted reproductive technologies (ARTs) has resulted in new ethical dilemmas. Though women occupy a central role in the reproductive process, within the ART paradigm, the importance accorded to the embryo commonly surpasses that given to the mother. This commentary questions the increasing tendency to position the embryonic subject in an antagonistic relation with the mother. I examine how the mother's reproductive autonomy is compromised in relation to that of her embryo and argue in favour of doing away with the subject-object dyad between them, particularly in the contexts of surrogacy and abortion...
April 2018: Indian Journal of Medical Ethics
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