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https://www.readbyqxmd.com/read/29037589/a-twin-purification-enrichment-procedure-based-on-two-versatile-solid-liquid-extracting-agents-for-efficient-uptake-of-ultra-trace-levels-of-lorazepam-and-clonazepam-from-complex-bio-matrices
#1
Maryam Hemmati, Maryam Rajabi, Alireza Asghari
In this research work, two consecutive dispersive solid/liquid phase microextractions based on efficient extraction media were developed for the influential and clean pre-concentration of clonazepam and lorazepam from complicated bio-samples. The magnetism nature of the proposed nanoadsorbent proceeded the clean-up step conveniently and swiftly (∼5min), pursued by a further enrichment via a highly effective and rapid emulsification microextraction process (∼4min) based on a deep eutectic solvent (DES). Finally, the instrumental analysis step was practicable via high performance liquid chromatography-ultraviolet detection...
September 21, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29034597/effect-of-composite-type-and-placement-technique-on-cuspal-strain
#2
Vilhelm G Ólafsson, André V Ritter, Edward J Swift, Lee W Boushell, Ching-Chang Ko, Gabrielle R Jackson, Sumitha N Ahmed, Terence E Donovan
OBJECTIVE: To compare the cuspal strain in Class II restorations made with bulk-fill and conventional composite resins. MATERIALS AND METHODS: Fifty extracted maxillary premolars were mounted into phenolic rings and divided into five groups (n = 10). Specimens received standardized MOD preparations. A two-step self-etch adhesive was applied and the preparations were restored using a custom matrix as follows: Filtek Supreme Ultra in eight 2-mm increments (FSUI); Filtek Supreme Ultra in bulk (FSUB); SonicFill in bulk (SF); SureFil SDR flow in bulk, covered with a 2-mm occlusal layer of Filtek Supreme Ultra (SDR/FSU); Tetric EvoCeram Bulk Fill in bulk (TEBF)...
October 16, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/29033717/comparison-of-oropharyngeal-leak-pressure-of-air-q%C3%A2-i-gel%C3%A2-and-laryngeal-mask-airway-supreme%C3%A2-in-adult-patients-during-general-anesthesia-a-randomized-controlled-trial
#3
Srinath Damodaran, Sameer Sethi, Surender Kumar Malhotra, Tanvir Samra, Souvik Maitra, Vikas Saini
STUDY OBJECTIVE: Various randomized controlled trials and a meta-analysis have compared i-gel™ and laryngeal mask airway Supreme™ (LMA-S™) in adult patients and found that both the devices provided equivalent oropharyngeal leak pressure (OLP). However, no randomized controlled trial has compared air-Q™ with i-gel™ and LMA-S™ in adult patient. Hence, we designed this study to compare air-Q™ with LMA-S™ and i-gel™ in adult patients. MATERIALS AND METHODS: A total of 75 adult patients of the American Society of Anesthesiologists physical status I/II of both sexes, between 18 and 60 years, were included in this prospective randomized controlled trial conducted in a tertiary care center...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29022490/the-german-federal-supreme-court-also-granted-a-compulsory-patent-license-for-the-first-time-in-its-history
#4
Takeshi S Komatani
No abstract text is available yet for this article.
October 12, 2017: Pharmaceutical Patent Analyst
https://www.readbyqxmd.com/read/29019999/the-supreme-court-s-interpretation-of-the-biosimilars-statute-and-the-value-of-certainty
#5
Irena Royzman, Nathan Monroe-Yavneh
No abstract text is available yet for this article.
October 11, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28994655/functional-comparison-between-buma-supreme-biodegradable-polymer-sirolimus-eluting-and-durable-polymer-zotarolimus-eluting-coronary-stents-using-quantitative-flow-ratio-pioneer-qfr-substudy
#6
Taku Asano, Yuki Katagiri, Carlos Collet, Erhan Tenekecioglu, Yosuke Miyazaki, Yohei Sotomi, Giovanni Amoroso, Adel Aminian, Salvatore Brugaletta, Mathias Vrolix, Rosana Hernandez-Antolín, Pim van de Harst, Andres Iñiguez, Luc Janssens, Pieter Smits, Joanna J Wykrzykowska, Vasco Gama Ribeiro, Helder Periera, Pedro Canas da Silva, Jan J Piek, Johan H C Reiber, Clemens von Birgelen, Manel Sabaté, Yoshinobu Onuma, Patrick W Serruys
AIMS: Quantitative Flow Ratio (QFR) based on 3-dimensional quantitative coronary angiography (3D-QCA) is a novel method to assess the physiological functionality after treatment with stents. The current study aimed to evaluate the difference in physiological functionality 9 months after implantation of a bioresorbable polymer-based sirolimus-eluting stent with an electrografting base layer (BuMA Supreme: B-SES) versus a durable polymer-based zotarolimus-eluting stent (Resolute: R-ZES)...
October 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28989128/mechanical-and-physical-properties-of-two-different-resin-based-materials-a-comparative-study
#7
Hosam Baeshen, Basem N Alturki, Wjoud W Albishi, Fahad M Alsadi, Khaled M El-Tubaigy
AIM: The purpose of this study was to evaluate the degree of conversion (DC) of two different resin-based composite materials (nanofill composite and ormocer) and correlate it with some mechanical properties of these two restorative materials. MATERIALS AND METHODS: Two different resin-based materials (Filtek Supreme XT and Admira) were tested. A total of 30 samples of each type of selected composite were prepared. Specimens were immersed in distilled water for 24 hours...
October 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28989123/effect-of-two-minute-application-of-35-sodium-ascorbate-on-composite-bond-strength-following-bleaching
#8
Eman H Ismail, Evren Kilinc, Patrick C Hardigan, James K Rothrock, Jeffrey Y Thompson, Cristina Garcia-Godoy
AIM: The aim of this study is to assess the effect of 35% sodium ascorbate on microtensile bond strength of dentin immediately after bleaching with 35% hydrogen peroxide. MATERIALS AND METHODS: A total of 25 sound human 3(rd) molars were collected. Teeth were randomly divided into five groups for different treatments: Group I [bleaching + immediate bonding (i.e., restoration)], group II (bleaching + delayed bonding), group III (bleaching + sodium ascorbate + immediate bonding), group IV (bleaching + sodium ascorbate + delayed bonding), and group V (bonding only)...
October 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28985348/elbow-room-for-best-practice-montgomery-patients-values-and-balanced-decision-making-in-person-centred-clinical-care
#9
Jonathan Herring, K M W Fulford, Michael Dunn, Ashok I Handa
The UK Supreme Court Montgomery judgment marks a decisive shift in the legal test of duty of care in the context of consent to treatment, from the perspective of the clinician (as represented by Bolam rules) to that of the patient. A majority of commentators on Montgomery have focused on the implications of the judgment for disclosure of risk. In this article, we set risk disclosure in context with three further elements of the judgment: benefits, options, and dialogue. These elements, we argue, taken together with risk disclosure, reflect the origins of the Montgomery ruling in a model of consent based on autonomy of patient choice through shared decision-making with their doctor...
July 19, 2017: Medical Law Review
https://www.readbyqxmd.com/read/28981864/a-human-rights-perspective-of-assisted-suicide-accounting-for-disparate-jurisprudence
#10
Stevie S Martin
This article critically examines the decision of the New Zealand High Court in Seales v Attorney-General [2015] NZHC 1239, which rejected the claim that that country's blanket ban on assisted suicide violated various rights enshrined in the New Zealand Bill of Rights. That outcome runs contrary to the Canadian Supreme Court's decision in Carter v Canada (Attorney General) [2015] 1 SCR 331. This disparity in result arose despite overt similarities between the rights documents in each of the jurisdictions and, more significantly, notwithstanding the fact that the trial judge in Seales placed heavy reliance upon the decision in Carter...
September 11, 2017: Medical Law Review
https://www.readbyqxmd.com/read/28976846/polymerization-behavior-and-mechanical-properties-of-high-viscosity-bulk-fill-and-low-shrinkage-resin-composites
#11
S Shibasaki, T Takamizawa, K Nojiri, A Imai, A Tsujimoto, H Endo, S Suzuki, S Suda, W W Barkmeier, M A Latta, M Miyazaki
The present study determined the mechanical properties and volumetric polymerization shrinkage of different categories of resin composite. Three high viscosity bulk fill resin composites were tested: Tetric EvoCeram Bulk Fill (TB, Ivoclar Vivadent), Filtek Bulk Fill posterior restorative (FB, 3M ESPE), and Sonic Fill (SF, Kerr Corp). Two low-shrinkage resin composites, Kalore (KL, GC Corp) and Filtek LS Posterior (LS, 3M ESPE), were used. Three conventional resin composites, Herculite Ultra (HU, Kerr Corp), Estelite ∑ Quick (EQ, Tokuyama Dental), and Filtek Supreme Ultra (SU, 3M ESPE), were used as comparison materials...
October 4, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28959763/fracture-toughness-of-nanohybrid-and-hybrid-composites-stored-wet-and-dry-up-to-60-days
#12
M Sookhakiyan, S Tavana, Y Azarnia, R Bagheri
STATEMENT OF PROBLEM: Patients' demand for tooth-colored restoratives in the posterior region is increasing. Clinicians use universal nanohybrid resin composites for both anterior and posterior regions. There are few published reports comparing fracture toughness of nonohybrids and that of hybrid composite stored wet and dry. OBJECTIVES: To investigate the fracture toughness of three nanohybrids compared to that of a hybrid resin composite stored dry or wet up to 60 days, using four-point bending test...
March 2017: J Dent Biomater
https://www.readbyqxmd.com/read/28957741/cannabis-for-personal-use-in-the-supreme-court-of-mexico-legal-case-and-potential-for-policy-change
#13
Andrés Aguinaco, Aram Barra
This viewpoint outlines how the legal case used by the authors in the litigation strategy of the "SMART Case" on medical marihuana, which was ruled positively by Mexico's Supreme Court on November 4th, 2015. The main objective of the text is to share key arguments that may be used by other litigation strategies around the world.
September 25, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28956399/-biofilm-development-and-environmental-determinants-in-vibrio-cholerae
#14
Quanmin Wang, Yao Ma, Lijun Liu, Jun Zhu, Zhi Liu
Biofilm associated Vibrio cholerae exhibits hypervirulence and supreme fitness against the harsh stresses during its infectious cycle. It is important to study the relationships between the regulation mechanism of V. cholerae biofilm development and its environmental adaption in host niche and aquatic habitat. Here, we summarize the recent advances in V. cholerae biofilm, including biofilm compositions, development and regulation. Particularly, we extensively discuss how V. cholerae fosters its biofilm architecture and assembly via sensing and responding various environmental determinants, such as bacterium self-produced molecules, natural environment components and host factors...
September 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28943724/using-a-moot-to-develop-students-understanding-of-human-cloning-and-statutory-interpretation
#15
Shaun D Pattinson, Vanessa Kind
This article reports and analyses the method and findings from a 3-year interdisciplinary project investigating how the medium of law can support understanding of socio-scientific issues. Law represents one of the most important means by which society decides and communicates its values. Activities mirroring legal processes therefore have significant potential to inform, inspire and involve school students in exploring the conceptual, social and ethical issues relating to developments in biomedical science...
September 2017: Medical Law International
https://www.readbyqxmd.com/read/28939736/u-s-case-law-and-legal-precedent-affirming-the-due-process-rights-of-immigrants-fleeing-persecution
#16
Shawn S Sidhu, Ramnarine Boodoo
The political discourse on domestic immigration policy has shifted rapidly in recent years, mirrored by similar shifts in the geopolitical climate worldwide. However, a nuanced assessment of the legal basis backing such rhetoric is sorely lacking. This article examines the historical, legal, and case law precedent as it pertains specifically to immigrants who are fleeing persecution and residing within the United States. Due process rights emerged from the Fifth, Sixth, and Fourteenth Constitutional Amendments and have been expanded to include this population through several sequential United States Supreme Court Cases...
September 2017: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/28937005/quota-in-specialty-and-super-specialty-courses-what-does-the-judiciary-say
#17
Mukul Chandra Kapoor, Shubhendu Anand
Reservations in super-specialty courses have been controversial for decades. A number of practising doctors, medical students and others in society have wanted to do away with reservations in specialty and super-specialty courses, while there are others in favour of persisting with reservations. Article 15 (4) of the Constitution of India states that nothing shall prevent the State from making any special provision for the advancement of any socially and educationally backward classes of citizens or for the Scheduled Castes/Tribes...
May 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28928564/comparison-of-i-gel%C3%A2-and-laryngeal-mask-airway-supreme%C3%A2-in-different-head-and-neck-positions-in-spontaneously-breathing-pediatric-population
#18
Swati Gupta, Neelam Dogra, Kanchan Chauhan
BACKGROUND: Although the advantages of ventilation with i-gel™ and laryngeal mask airway Supreme (LMA-Supreme™) has been well documented, they are still under debate for surgeries requiring flexion and extension of neck such as thyroid surgery, tonsillectomy, and neck exploration. Hence, we conducted a study to demonstrate the effect of neck flexion and extension in spontaneously breathing anesthetized pediatric patients utilizing i-gel™ and LMA-Supreme™. METHODS: A prospective, randomized comparative study was conducted on sixty children, thirty each in i-gel™ and LMA-Supreme™ group...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28923787/first-in-man-randomized-comparison-of-buma-supreme-biodegradable-polymer-sirolimus-eluting-versus-durable-polymer-zotarolimus-eluting-coronary-stents-the-pioneer-trial
#19
Clemens von Birgelen, Taku Asano, Giovanni Amoroso, Adel Aminian, Salvatore Brugaletta, Mathias Vrolix, Rosana Hernandez-Antolín, Pim van de Harst, Andres Iñiguez, Luc Janssens, Pieter C Smits, Joanna J Wykrzykowska, Vasco Gama Ribeiro, Helder Periera, Pedro Canas da Silva, Jan J Piek, Yoshinobu Onuma, Patrick W Serruys, Manel Sabaté
AIMS: A second iteration of a sirolimus-eluting stent (SES) that has a biodegradable PLGA-polymer coating with electrografting base layer on a thin-strut (80µm) cobalt-chromium platform (BuMA Supreme; SINOMED, Tianjin, China) has been developed. This first-in-man trial assessed the efficacy and safety of the novel device. METHODS AND RESULTS: This randomized, multi-center, single-blinded, non-inferiority trial compared BuMA Supreme SES versus contemporary durable polymer zotarolimus-eluting stents (ZES) in terms of angiographic in-stent late lumen loss (LLL) at 9-months follow-up as the primary endpoint...
September 19, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28903789/the-mind-of-suicide-terrorists
#20
Donatella Marazziti, Antonello Veltri, Armando Piccinni
After reviewing the available literature about the main hypotheses on suicide terrorism and the psychological characteristics of terrorists that have been proposed throughout the years, the present authors have put forward some personal considerations on what the distinctive traits of today's suicide bombers might be. In spite of the heterogeneity and paucity of "real" data, it is evident that there is no peculiar familial, educational, or socioeconomic factors that may account for religious radicalization leading to suicide terrorism...
September 14, 2017: CNS Spectrums
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