Michael Pichler, Prashanthi Vemuri, Alejandro A Rabinstein, Jeremiah Aakre, Kelly D Flemming, Robert D Brown, Neeraj Kumar, Kejal Kantarci, Walter Kremers, Michelle M Mielke, David S Knopman, Clifford R Jack, Ronald C Petersen, Val Lowe, Jonathan Graff-Radford
BACKGROUND AND PURPOSE: Superficial siderosis (SS) is characterized by hemosiderin deposition in the superficial layers of the central nervous system and can be seen during postmortem examination or with iron-sensitive magnetic resonance imaging techniques. The distribution of SS may predict the probable underlying cause. This study aimed to report the prevalence and natural history of SS in a population-based study. METHODS: Brain magnetic resonance imaging scans from the MCSA (Mayo Clinic Study of Aging), a population-based study of residents 50 to 89 years of age in Olmsted County, Minnesota, were reviewed...
December 2017: Stroke; a Journal of Cerebral Circulation