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Ki-Chul Kwon, Young-Tae Lim, Chang-Won Shin, Munkh-Uchral Erdenebat, Jae-Moon Hwang, Nam Kim
We propose and implement an integral imaging microscope with extended depth-of-field (DoF) using a bifocal holographic micro lens array (MLA). The properties of the two MLAs are switched via peristrophic multiplexing, where different properties of the MLA are recorded onto the single holographic optical element (HOE). The recorded MLA properties are perpendicular to each other: after the first mode is recorded, the HOE is rotated by 90° clockwise, and the second mode is recorded. The experimental results confirm that the DoF of the integral imaging microscopy system is extended successfully by using the bifocal MLA...
August 15, 2017: Optics Letters
C Alpmann, C Schlickriede, E Otte, C Denz
Generation of complex Poincaré beams is enabled by amplitude and phase modulation accompanied by simultaneous spatially polarization structuring. A holographic system to tailor complex light fields and optical angular momentum structures forecasts promising applications in quantum communication and optical trapping. Experimental results are presented together with simulations of complex Poincaré beams embedding different types of polarization singularities. Additionally, parameters of the dynamic polarization modulation system are discussed and analyzed to demonstrate the enormous capability of the method...
August 14, 2017: Scientific Reports
Marjan Heidari, Bahareh Dabirmanesh, Hossein Mahdavi, Khosro Khajeh
Nowadays sensors and especially biosensors play an important role in medical diagnosis and detection of food and environment contaminations. Biosensors’ facilities have been improved significantly by using technologies such as surface plasmon resonance, microfluidics, laser, and electrochemistry. These technologies are now available on chips in micro- and nano-scale and are capable of measuring the quantity of more than one analyte at once. One branch of these sensors is the holographic (bio)sensor. Reflection holographic sensors, which are optical devices fabricated based on Bragg’s law, can diffract light with specific wavelength as they absorb or release special ions or molecule depending on their polymer structure...
August 15, 2017: Iranian Biomedical Journal
YoungJu Jo, Sangjin Park, JaeHwang Jung, Jonghee Yoon, Hosung Joo, Min-Hyeok Kim, Suk-Jo Kang, Myung Chul Choi, Sang Yup Lee, YongKeun Park
Establishing early warning systems for anthrax attacks is crucial in biodefense. Despite numerous studies for decades, the limited sensitivity of conventional biochemical methods essentially requires preprocessing steps and thus has limitations to be used in realistic settings of biological warfare. We present an optical method for rapid and label-free screening of Bacillus anthracis spores through the synergistic application of holographic microscopy and deep learning. A deep convolutional neural network is designed to classify holographic images of unlabeled living cells...
August 2017: Science Advances
Jin-Yang Jiang, Yao Liu, Hong-Yan Chu, Danqian Wang, Han Ma, Wei Sun
In this study, the pitting behaviour of a new corrosion-resistant alloy steel (CR) is compared to that of low-carbon steel (LC) in a simulated concrete pore solution with a chloride concentration of 5 mol/L. The electrochemical behaviour of the bars was characterised using linear polarisation resistance (LPR) and electrochemical impedance spectroscopy (EIS). The pitting profiles were detected by reflective digital holographic microscopy (DHM), scanning electron microscopy (SEM), and the chemical components produced in the pitting process were analysed by X-ray energy dispersive spectroscopy (EDS)...
August 4, 2017: Materials
Lianlin Li, Tie Jun Cui, Wei Ji, Shuo Liu, Jun Ding, Xiang Wan, Yun Bo Li, Menghua Jiang, Cheng-Wei Qiu, Shuang Zhang
Metasurfaces have enabled a plethora of emerging functions within an ultrathin dimension, paving way towards flat and highly integrated photonic devices. Despite the rapid progress in this area, simultaneous realization of reconfigurability, high efficiency, and full control over the phase and amplitude of scattered light is posing a great challenge. Here, we try to tackle this challenge by introducing the concept of a reprogrammable hologram based on 1-bit coding metasurfaces. The state of each unit cell of the coding metasurface can be switched between '1' and '0' by electrically controlling the loaded diodes...
August 4, 2017: Nature Communications
Wei-Feng Hsu, Ming-Hong Weng
This paper presents a holographic projection display in which a phase-only spatial light modulator (SLM) performs three functions: beam shaping, image display, and speckle reduction. The functions of beam shaping and image display are performed by dividing the SLM window into four sub-windows loaded with different diffractive phase elements (DPEs). The DPEs are calculated using a modified iterative Fourier transform algorithm (IFTA). The function of speckle reduction is performed using temporal integration of display images containing speckles...
September 9, 2016: Materials
Minghuan Liu, Yonggang Liu, Zenghui Peng, Shaoxin Wang, Qidong Wang, Quanquan Mu, Zhaoliang Cao, Li Xuan
Organic solid-state tri-wavelength lasing was demonstrated from dye-doped holographic polymer-dispersed liquid crystal (HPDLC) distributed feedback (DFB) laser with semiconducting polymer poly[-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene-vinylene] (MEH-PPV) and laser dye [4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran] (DCM) by a one-step holography technique, which centered at 605.5 nm, 611.9 nm, and 671.1 nm. The temperature-dependence tuning range for the tri-wavelength dye-doped HPDLC DFB laser was as high as 8 nm...
May 7, 2017: Materials
Mostafa A Ellabban, Gašper Glavan, Jürgen Klepp, Martin Fally
A detailed investigation of the recording, as well as the readout of transmission gratings in composites of poly(ethylene glycol) dimethacrylate (PEGDMA) and ionic liquids is presented. Gratings with a period of about 5.8 micrometers were recorded using a two-wave mixing technique with a coherent laser beam of a 355-nm wavelength. A series of samples with grating thicknesses d 0 = 10 … 150 micrometers, each for two different exposure times, was prepared. The recording kinetics, as well as the post-exposure properties of the gratings were monitored by diffracting a low intensity probe beam at a wavelength of 633 nm for Bragg incidence...
December 24, 2016: Materials
Devon Boyne, Joshua Orlicki, Scott Walck, Alice Savage, Thomas Li, Mark Griep
Nanoscale engineering of noble metal particles has provided numerous material configurations to selectively confine and manipulate light across the electromagnetic spectrum. Transitioning these materials to a composite form while maintaining the desired resonance properties has proven challenging. In this work, the successful integration of plasmon-focusing gold nanostars into polymer nanocomposites is demonstrated. Tailored gold nanostars are produced with over a 90% yield and methods to control the branching structures are shown...
July 27, 2017: Nanotechnology
Violeta L Calin, Mona Mihailescu, Nicolae Mihale, Alexandra V Baluta, Eugenia Kovacs, Tudor Savopol, Mihaela G Moisescu
Changes in optical and shape-related characteristics of B16F10 cells after electroporation were investigated using digital holographic microscopy (DHM). Bipolar rectangular pulses specific for electrochemotherapy were used. Electroporation was performed in an "off-axis" DHM set-up without using exogenous markers. Two types of cell parameters were monitored seconds and minutes after pulse train application: parameters addressing a specifically defined area of the cell (refractive index and cell height) and global cell parameters (projected area, optical phase shift profile and dry mass)...
April 1, 2017: Biomedical Optics Express
Zhiyuan Shen, Xiaorui Guo, Yilong Zhang, Dongmei Li, Yonghong He
In this work, we used a short coherence digital holographic microscopy system to demonstrate cross-talk noise suppression and imaging performance enhancement by optical clearing. Performance of the system on both phantom and in vitro porcine skin tissues before and after the treatment of 70% v./v. glycerol-saline solution was investigated. Our results showed that optical clearing effectively inhibits the cross-talk noise and improves the image quality in the deep of the in vitro porcine skin tissues. The imaging depth was increased by about 30% after topical application of the glycerol-saline solution for 30 min...
April 1, 2017: Biomedical Optics Express
Sašo Grozdanov, Wilke van der Schee
We initiate a holographic study of coupling-dependent heavy ion collisions by analyzing, for the first time, the effects of leading-order, inverse coupling constant corrections. In the dual description, this amounts to colliding gravitational shock waves in a theory with curvature-squared terms. We find that, at intermediate coupling, nuclei experience less stopping and have more energy deposited near the light cone. When the decreased coupling results in an 80% larger shear viscosity, the time at which hydrodynamics becomes a good description of the plasma created from high energy collisions increases by 25%...
July 7, 2017: Physical Review Letters
Yuanbo Deng, Daping Chu
Coherence properties of different light sources and how they affect the image quality of holographic display are investigated. Temporal coherence is related to the intrinsic spectrum bandwidth of the light source, while spatial coherence can be affected by the size of the light source and propagation distance in use. These two coherence properties are measured for various light sources of diode-pumped solid-state (DPSS) laser, laser diode (LD), light emitting diode (LED), super luminescent light emitting diode (sLED) and micro light emitting diode (mLED) in different settings, together with the quality of the holographic reconstructed images...
July 19, 2017: Scientific Reports
Biagio Mandracchia, Vittorio Bianco, Zhe Wang, Martina Mugnano, Alessia Bramanti, Melania Paturzo, Pietro Ferraro
In the current trend of miniaturization and simplification of imaging flow cytometry, Lab-on-a-Chip (LoC) microfluidic devices represent an innovative and cost-effective solution. In this framework, we propose for the first time a novel platform based on the compactness of a holographic microscope slide (HMS) in combination with the new computational features of space-time digital holography (STDH) that uses a 1D linear sensor array (LSA) instead of 2D CCD or CMOS cameras to respond to real diagnostic needs...
August 8, 2017: Lab on a Chip
Dhananjay Kumar Singh, Caroline C Ahrens, Wei Li, Siva A Vanapalli
We introduce inline digital holographic microscopy (in-line DHM) as a label-free technique for detecting tumor cells in blood. The optimized DHM platform fingerprints every cell flowing through a microchannel at 10 000 cells per second, based on three features - size, maximum intensity and mean intensity. To identify tumor cells in a background of blood cells, we developed robust gating criteria using machine-learning approaches. We established classifiers from the features extracted from 100 000-cell training sets consisting of red blood cells, peripheral blood mononuclear cells and tumor cell lines...
July 18, 2017: Lab on a Chip
Manuel Bedrossian, Chris Lindensmith, Jay L Nadeau
Detection of extant microbial life on Earth and elsewhere in the Solar System requires the ability to identify and enumerate micrometer-scale, essentially featureless cells. On Earth, bacteria are usually enumerated by culture plating or epifluorescence microscopy. Culture plates require long incubation times and can only count culturable strains, and epifluorescence microscopy requires extensive staining and concentration of the sample and instrumentation that is not readily miniaturized for space. Digital holographic microscopy (DHM) represents an alternative technique with no moving parts and higher throughput than traditional microscopy, making it potentially useful in space for detection of extant microorganisms provided that sufficient numbers of cells can be collected...
July 14, 2017: Astrobiology
Shengyun Ji, Liang Yang, Yanlei Hu, Jincheng Ni, Wenqiang Du, Jiawen Li, Gang Zhao, Dong Wu, Jiaru Chu
Transparent microtubes can function as unique cell culture scaffolds, because the tubular 3D microenvironment they provide is very similar to the narrow space of capillaries in vivo. However, how to realize the fabrication of microtube-arrays with variable cross-section dynamically remains challenging. Here, a dynamic holographic processing method for producing high aspect ratio (≈20) microtubes with tunable outside diameter (6-16 µm) and inside diameter (1-10 µm) as yeast culture scaffolds is reported...
July 11, 2017: Small
Aniruddha Ray, Mustafa Ugur Daloglu, Joslynn Ho, Avee Torres, Euan Mcleod, Aydogan Ozcan
Caused by the herpes simplex virus (HSV), herpes is a viral infection that is one of the most widespread diseases worldwide. Here we present a computational sensing technique for specific detection of HSV using both viral immuno-specificity and the physical size range of the viruses. This label-free approach involves a compact and cost-effective holographic on-chip microscope and a surface-functionalized glass substrate prepared to specifically capture the target viruses. To enhance the optical signatures of individual viruses and increase their signal-to-noise ratio, self-assembled polyethylene glycol based nanolenses are rapidly formed around each virus particle captured on the substrate using a portable interface...
July 7, 2017: Scientific Reports
Svitlana Bugaychuk, Andrey Iljin, Oleg Lytvynenko, Ludmila Tarakhan, Lulmila Karachevtseva
Nonlinear-optical response of photorefractive hybrid liquid crystal (LC) cells has been studied by means of dynamic holographic technique in two-wave mixing arrangement. The LC cells include nonuniform silicon substrates comprising a micrometer-range photonic crystal. A thin LC layer is set between silicon substrate and a flat glass substrate covered by a transparent (ITO) electrode. A dynamic diffraction grating was induced in the LC volume by the two-wave mixing of laser beams with simultaneous application of DC electric field to the cell...
December 2017: Nanoscale Research Letters
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