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https://www.readbyqxmd.com/read/28430958/survey-of-institutional-policies-for-provision-of-cmv-safe-blood-in-ontario
#1
Laura Finlay, Pria Nippak, James Tiessen, Winston Isaac, Jeannie Callum, Christine Cserti-Gazdewich
Objectives: Debate continues on whether leukoreduction alone (LR) is sufficiently similar to leukoreduced cellular products drawn from cytomegalovirus (CMV)-seronegative (SN) donors to minimize the risk of transfusion-transmitted CMV (TT-CMV). We sought to determine the policy, inventory, and practice landscape of the province for TT-CMV mitigation. Methods: A web-based survey was distributed to hospitals in Ontario by Canadian Blood Services to collect data on their policies with respect to TT-CMV prevention...
November 1, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28430490/diffused-vorticity-and-moment-of-inertia-of-a-spin-orbit-coupled-bose-einstein-condensate
#2
Sandro Stringari
By developing the hydrodynamic theory of spinor superfluids, we calculate the moment of inertia of a harmonically trapped Bose-Einstein condensate with spin-orbit coupling. We show that the velocity field associated with the rotation of the fluid exhibits diffused vorticity, in contrast to the irrotational behavior characterizing a superfluid. Both Raman-induced and Rashba spin-orbit couplings are considered. In the first case the moment of inertia takes the rigid value at the transition between the plane wave and the single minimum phase, while in the latter case the rigid value is achieved in the limit of isotropic Rashba coupling...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28430481/ultimate-limit-in-the-spectral-resolution-of-extreme-ultraviolet-frequency-combs
#3
C Corsi, I Liontos, M Bellini, S Cavalieri, P Cancio Pastor, M Siciliani de Cumis, R Eramo
We present the results of direct interferometric measurements on the pulse-to-pulse phase jitter of a metrological, fiber-based, infrared (IR) frequency comb. We show that the short-time evolution of such phase fluctuations, which cannot be actively controlled by any feedback system, imposes a stringent limit on the tooth linewidth of extreme ultraviolet (XUV) combs produced by high-order harmonic conversion, thus explaining the difference of 9 orders of magnitude between the coherence times of state-of-the-art IR and XUV frequency combs...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28430235/fiber-bragg-grating-interrogation-using-wavelength-modulated-tunable-distributed-feedback-lasers-and-a-fiber-optic-mach-zehnder-interferometer
#4
Anirban Roy, Arup Lal Chakraborty, Chandan Kumar Jha
This paper demonstrates a technique of high-resolution interrogation of two fiber Bragg gratings (FBGs) with flat-topped reflection spectra centered on 1649.55 nm and 1530.182 nm with narrow line width tunable semiconductor lasers emitting at 1651.93 nm and 1531.52 nm, respectively. The spectral shift of the reflection spectrum in response to temperature and strain is accurately measured with a fiber-optic Mach-Zehnder interferometer that has a free spectral range of 0.0523 GHz and a broadband photodetector...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430233/sensitivity-tests-on-the-convergence-tendency-of-the-scattering-order-formulation-of-the-discrete-dipole-approximation
#5
Carynelisa Haspel, Masada Tzabari
In this study, we performed a series of sensitivity tests in order to elucidate the convergence tendency of the scattering order formulation (SOF) of the discrete dipole approximation (DDA). Using both the original formulation of the SOF and a new marching SOF, the progression of orders of scattering marches, along with the propagation of the incident plane wave through the scatterer, allow dipoles that come into steady-state oscillation with the incident wave earlier to more quickly advance to the next order of scattering that is local to them...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28429254/biomarkers-predicting-bone-turnover-in-the-setting-of-ckd
#6
REVIEW
Pieter Evenepoel, Etienne Cavalier, Patrick C D'Haese
PURPOSE OF THE REVIEW: Impaired bone quality contributes to the increased fracture risk in chronic kidney disease patients. Both low and high turnover bone disease may compromise bone quality. The question arises whether bone biomarkers may be additive or replace bone histormorphometry for diagnosing the extremes of bone turnover. RECENT FINDINGS: Studies exploring the performance of established and emerging bone biomarkers against histomorphometric assessment of bone turnover are limited and overall yield inconclusive results as to their diagnostic utility...
April 20, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28429023/probing-the-role-of-excited-states-in-ionization-of-acetylene
#7
Daniel Dundas, Peter Mulholland, Abigail Wardlow, Alejandro de la Calle
Ionization of acetylene by linearly-polarized, vacuum ultraviolet (VUV) laser pulses is modelled using time-dependent density functional theory. Several laser wavelengths are considered including one that produces direct ionization to the first excited cationic state while another excites the molecules to a Rydberg series incorporating an autoionizing state. We show that for the wavelengths and intensities considered, ionization is greatest whenever the molecule is aligned along the laser polarization direction...
April 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28428549/low-noise-time-resolved-optical-sensing-of-electromagnetic-pulses-from-petawatt-laser-matter-interactions
#8
T S Robinson, F Consoli, S Giltrap, S J Eardley, G S Hicks, E J Ditter, O Ettlinger, N H Stuart, M Notley, R De Angelis, Z Najmudin, R A Smith
We report on the development and deployment of an optical diagnostic for single-shot measurement of the electric-field components of electromagnetic pulses from high-intensity laser-matter interactions in a high-noise environment. The electro-optic Pockels effect in KDP crystals was used to measure transient electric fields using a geometry easily modifiable for magnetic field detection via Faraday rotation. Using dielectric sensors and an optical fibre-based readout ensures minimal field perturbations compared to conductive probes and greatly limits unwanted electrical pickup between probe and recording system...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428546/influence-of-intermixing-at-the-ta-cofeb-interface-on-spin-hall-angle-in-ta-cofeb-mgo-heterostructures
#9
Monika Cecot, Łukasz Karwacki, Witold Skowroński, Jarosław Kanak, Jerzy Wrona, Antoni Żywczak, Lide Yao, Sebastiaan Dijken, Józef Barnaś, Tomasz Stobiecki
When a current is passed through a non-magnetic metal with strong spin-orbit coupling, an orthogonal spin current is generated. This spin current can be used to switch the magnetization of an adjacent ferromagnetic layer or drive its magnetization into continuous precession. The interface, which is not necessarily sharp, and the crystallographic structure of the nonmagnetic metal can both affect the strength of current-induced spin-orbit torques. Here, we investigate the effects of interface intermixing and film microstructure on spin-orbit torques in perpendicularly magnetized Ta/Co40Fe40B20/MgO trilayers with different Ta layer thickness (5 nm, 10 nm, 15 nm), greater than the spin diffusion length...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428420/a-parity-breaking-electronic-nematic-phase-transition-in-the-spin-orbit-coupled-metal-cd2re2o7
#10
J W Harter, Z Y Zhao, J-Q Yan, D G Mandrus, D Hsieh
Strong electron interactions can drive metallic systems toward a variety of well-known symmetry-broken phases, but the instabilities of correlated metals with strong spin-orbit coupling have only recently begun to be explored. We uncovered a multipolar nematic phase of matter in the metallic pyrochlore Cd2Re2O7 using spatially resolved second-harmonic optical anisotropy measurements. Like previously discovered electronic nematic phases, this multipolar phase spontaneously breaks rotational symmetry while preserving translational invariance...
April 21, 2017: Science
https://www.readbyqxmd.com/read/28427734/comparison-of-outcomes-and-prognosis-of-patients-with-versus-without-newly-diagnosed-diabetes-mellitus-after-primary-percutaneous-coronary-intervention-for-st-elevation-myocardial-infarction-the-horizons-ami-study
#11
Konstanze Ertelt, Sorin J Brener, Roxana Mehran, Ori Ben-Yehuda, Thomas McAndrew, Gregg W Stone
A history of diabetes mellitus (DM) is an independent predictor for adverse events in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention. Outcomes of patients with STEMI and newly diagnosed DM (NDM) are less well described. We used the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial database to identify the outcomes at 30 days and 3 years according to no, known, and NDM in patients with STEMI...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28427384/imbalanced-target-prediction-with-pattern-discovery-on-clinical-data-repositories
#12
Tak-Ming Chan, Yuxi Li, Choo-Chiap Chiau, Jane Zhu, Jie Jiang, Yong Huo
BACKGROUND: Clinical data repositories (CDR) have great potential to improve outcome prediction and risk modeling. However, most clinical studies require careful study design, dedicated data collection efforts, and sophisticated modeling techniques before a hypothesis can be tested. We aim to bridge this gap, so that clinical domain users can perform first-hand prediction on existing repository data without complicated handling, and obtain insightful patterns of imbalanced targets for a formal study before it is conducted...
April 20, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28426429/a-candidate-liquid-chromatography-mass-spectrometry-reference-method-for-the-quantification-of-the-cardiac-marker-1-32-b-type-natriuretic-peptide
#13
Attila F Torma, Kate Groves, Sabine Biesenbruch, Chris Mussell, Alan Reid, Steve Ellison, Rainer Cramer, Milena Quaglia
BACKGROUND: B-type natriuretic peptide (BNP) is a 32 amino acid cardiac hormone routinely measured by immunoassays to diagnose heart failure. While it is reported that immunoassay results can vary up to 45%, no attempt of standardization and/or harmonization through the development of certified reference materials (CRMs) or reference measurement procedures (RMPs) has yet been carried out. METHODS: B-type natriuretic peptide primary calibrator was quantified traceably to the International System of Units (SI) by both amino acid analysis and tryptic digestion...
April 20, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28426205/euro-6-unregulated-pollutant-characterization-and-statistical-analysis-of-aftertreatment-device-and-driving-condition-impact-on-recent-passenger-car-emissions
#14
Simon Martinet, Yao Liu, Cédric Louis, Patrick Tassel, Pascal Perret, Agnès Chaumond, Michel Andre
This study aims to measure and analyze unregulated compound emissions for two Euro 6 diesel and gasoline vehicles. The vehicles were tested on a chassis dynamometer under various driving cycles: Artemis driving cycles (urban, road and motorway), the New European Driving Cycle (NEDC) and the World Harmonized Light-Duty Test Cycle (WLTC) for Europe, and world approval cycles. The emissions of unregulated compounds - such as total particle number (PN) (over 5.6 nm), black carbon (BC), NO2, BTEX (benzene, toluene, ethylbenzene and xylene), carbonyl compounds and polycyclic aromatic hydrocarbons (PAHs) - were measured with several on-line devices and different samples were collected using cartridges and quartz filters...
April 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28426107/controversies-and-consensus-in-the-innovation-access-for-cancer-therapy-in-the-european-countries-on-the-subject-of-metastatic-prostate-cancer
#15
S Oudard, F Courbon
Innovative cancer therapies and advances in drug development have created new hopes for patients and health providers. The purpose of this article was to evaluate the discrepancies in the assessment of the magnitude of benefit of four new drugs (abiraterone acetate, enzalutamide, cabazitaxel, radium-223 dichloride) for the treatment of metastatic castration-resistant prostate cancer (mCRPC). The comparison was done among three European countries (UK, Germany and France) and Canada, according to the statement of each country and to the European Society of Medical Oncology (ESMO) Magnitude of Clinical Benefit Scale...
February 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28425220/associations-between-the-transsexual-voice-questionnaire-tvq-mtf-and-self-report-of-voice-femininity-and-acoustic-voice-measures
#16
Georgia Dacakis, Jennifer Oates, Jacinta Douglas
BACKGROUND: The Transsexual Voice Questionnaire (TVQ(MtF) ) was designed to capture the voice-related perceptions of individuals whose gender identity as female is the opposite of their birth-assigned gender (MtF women). Evaluation of the psychometric properties of the TVQ(MtF) is ongoing. AIMS: To investigate associations between TVQ(MtF) scores and (1) self-perceptions of voice femininity and (2) acoustic parameters of voice pitch and voice quality in order to evaluate further the validity of the TVQ(MtF) ...
April 19, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28424768/model-based-policymaking-a-framework-to-promote-ethical-good-practice-in-mathematical-modeling-for-public-health-policymaking
#17
Lisa A Boden, Iain J McKendrick
Mathematical models are increasingly relied upon as decision support tools, which estimate risks and generate recommendations to underpin public health policies. However, there are no formal agreements about what constitutes professional competencies or duties in mathematical modeling for public health. In this article, we propose a framework to evaluate whether mathematical models that assess human and animal disease risks and control strategies meet standards consistent with ethical "good practice" and are thus "fit for purpose" as evidence in support of policy...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28424487/power-flow-in-a-large-core-multimode-fiber-under-external-perturbation-and-its-applications
#18
Sen Qian, Yang Xu, Lisheng Zhong, Lei Su
Large core optical multimode fiber provides benefits such as a large light-coupling tolerance, easy handling, and delivery of higher light power without undesirable nonlinear effects. In this research, we exploit the effects of external perturbation on the power flow within the large core fiber and present two relevant applications, namely a perturbation sensor and a doughnut beam tuner. Since conventional multimode fiber power flow model does not take into consideration the perturbation effect, we modify the power flow model so that the influence of time varying perturbation can be theoretically analyzed...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28423901/estimation-of-nanodiamond-surface-charge-density-from-zeta-potential-and-molecular-dynamics-simulations
#19
Zhenpeng Ge, Yi Wang
Molecular dynamics simulations of nanoparticles (NPs) are increasingly used to study their interactions with various biological macromolecules. Such simulations generally require detailed knowledge of the surface composition of the NP under investigation. Even for some well-characterized nanoparticles, however, this knowledge is not always available. An example is nanodiamond, a nanoscale diamond particle with surface dominated by oxygen-containing functional groups. In this work, we explore using the harmonic restraint method developed by Venable et al...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28423823/reference-architecture-model-enabling-standards-interoperability
#20
Bernd Blobel
Advanced health and social services paradigms are supported by a comprehensive set of domains managed by different scientific disciplines. Interoperability has to evolve beyond information and communication technology (ICT) concerns, including the real world business domains and their processes, but also the individual context of all actors involved. So, the system must properly reflect the environment in front and around the computer as essential and even defining part of the health system. This paper introduces an ICT-independent system-theoretical, ontology-driven reference architecture model allowing the representation and harmonization of all domains involved including the transformation into an appropriate ICT design and implementation...
2017: Studies in Health Technology and Informatics
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