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Green laser

Jaidip Jagtap, Gayatri Sharma, Abdul K Parchur, Venkateswara Gogineni, Carmen Bergom, Sarah White, Michael J Flister, Amit Joshi
Vascular supply is a critical component of the tumor microenvironment (TME) and is essential for tumor growth and metastasis, yet the endogenous genetic modifiers that impact vascular function in the TME are largely unknown. To identify the host TME modifiers of tumor vascular function, we combined a novel genetic mapping strategy [Consomic Xenograft Model] with near-infrared (NIR) fluorescence imaging and multiparametric analysis of pharmacokinetic modeling. To detect vascular flow, an intensified cooled camera based dynamic NIR imaging system with 785 nm laser diode based excitation was used to image the whole-body fluorescence emission of intravenously injected indocyanine green dye...
February 1, 2018: Biomedical Optics Express
Pedro Jorge Louro Crugeira, Gustavo M Pires-Santos, Susana C P S de Oliveira, Fernando José Pires Sampaio, Neandder Andrade Correia, Sandra R C de A Fagnani, Fabio Alexandre Chinalia, Paulo Fernando de Almeida, Antônio L B Pinheiro
Cellulose has a highly diversified architecture and its enzymatic complexes are studied for achieving an efficient conversion and a high level of efficiency in the deconstruction of cellulolytic biomass into sugars. The aim of this investigation was to evaluate the effect of Laser or LED light in the cellulolytic activity (CMCase) and on the proliferation of the thermophilic microbial consortium used on the degradation process of a lignocellulosic biomass of green coconut shell. The irradiation protocol consisted of six Laser irradiations (λ660 ηm, 40 mW, 270 s, 13 J/cm2 ) or LED (λ632 ± 2 ηm, 145 mW, 44 s, 13 J/cm2 ) with 12- h time intervals in nutrient deprivation conditions...
March 8, 2018: Journal of Photochemistry and Photobiology. B, Biology
Daniela Litscher, Junying Wang, Gerhard Litscher, Guangzong Li, Peggy Bosch, Maurits van den Noort, Lu Wang
Background: One of the most commonly used auricular acupuncture points selected for different pain treatment regimens is Shenmen. This point on the ear has been recognized as having a wide number of applications, as found by scientific investigation. Methods: Within this crossover study, the ear acupoint Shenmen was stimulated with two different kinds of laser (green, 532 nm and yellow, 589 nm) in 22 healthy volunteers (13 female, 9 male; mean age ± SD = 25.3 ± 4.1 years; range 21-36 years). Both green and yellow lasers were used for 15 min in the same volunteers in two different sessions...
March 15, 2018: Medicines (Basel, Switzerland)
J S Green, N Booth, R J Dance, R J Gray, D A MacLellan, A Marshall, P McKenna, C D Murphy, C P Ridgers, A P L Robinson, D Rusby, R H H Scott, L Wilson
A key issue in realising the development of a number of applications of high-intensity lasers is the dynamics of the fast electrons produced and how to diagnose them. We report on measurements of fast electron transport in aluminium targets in the ultra-intense, short-pulse (<50 fs) regime using a high resolution temporally and spatially resolved optical probe. The measurements show a rapidly (≈0.5c) expanding region of Ohmic heating at the rear of the target, driven by lateral transport of the fast electron population inside the target...
March 14, 2018: Scientific Reports
Jonas Reinholz, Christopher Diesler, Susanne Schöttler, Maria Kokkinopoulou, Sandra Ritz, Katharina Landfester, Volker Mailänder
The transport of nanocarriers through barriers like the gut in a living organism involves the transcytosis of these nanocarriers through the cell layer dividing two compartments. Understanding how this process works is not only essential to further developing strategies for a more effective nanocarrier transport system but also for providing fundamental insights into the barrier function as a means of protection against micro- and nanoplastics in the food chain. We therefore set out to investigate the different uptake mechanisms, intracellular trafficking and the routes for exocytosis for small polystyrene nanoparticles (PS-NPs ca...
March 9, 2018: Acta Biomaterialia
Robert Naumann, Martin Goez
We present a novel photoredox catalytic system that delivers synthetically useable concentrations of hydrated electrons when illuminated with a green light-emitting diode (LED). The catalyst is a ruthenium complex protected by an anionic micelle, and the urate dianion serves as sacrificial donor confined to the aqueous bulk. Through its chemical properties, that donor not only suppresses charge recombination that would limit the electron yield but also enables this system to perform cross couplings via hydrated electrons, for which we report the first examples...
March 12, 2018: Chemistry: a European Journal
Yalan Rui, Bo Pang, Jinnan Zhang, Yuxi Liu, Huixin Hu, Zicun Liu, Sarah Ama Baidoo, Chang Liu, Yu Zhao, Siwen Li
A polyelectrolyte microcapsule-based layer-by-layer (LbL) technique has been widely used as a multifunctional vehicle for combined tumor therapy. Meanwhile, with the rapid development of combined tumour therapy, the challenge for designing multifunctional drug delivery system has attracted much more attention. Herein, we developed a new type of microcapsule (MC) system called MPA@siRNA@DOX@MC, which conjugated with siRNA and DOX as well as ICG-Der-02 (MPA) by electrostatic absorption. MPA as indocyanine green (ICG) fluorescence dye, exhibiting high fluorescence emission and photothermal conversion ability under NIR laser irradiation, was uploaded onto this drug system for realizing the controllable drug release and cancer theranostics...
March 11, 2018: Artificial Cells, Nanomedicine, and Biotechnology
Hao Zhang, Shun Wang, Keke Chang, Haifeng Sun, Qingqian Guo, Liuzheng Ma, Yatao Yang, Caihong Zou, Ling Wang, Jiandong Hu
Paper aging and degradation are growing concerns for those who are responsible for the conservation of documents, archives, and libraries. In this study, the paper aging was investigated using laser-induced fluorescence spectroscopy (LIFS), where the fluorescence properties of 47 paper samples with different ages were explored. The paper exhibits fluorescence in the blue-green spectral region with two peaks at about 448 nm and 480 nm under the excitation of 405 nm laser. Both fluorescence peaks changed in absolute intensities and thus the ratio of peak intensities was also influenced with the increasing ages...
January 1, 2018: Applied Spectroscopy
Sami A Alyahya, Marimuthu Govindarajan, Naiyf S Alharbi, Shine Kadaikunnan, Jamal M Khaled, Ramzi A Mothana, Mohammed N Al-Anbr, Baskaralingam Vaseeharan, Ramachandran Ishwarya, Mariappan Yazhiniprabha, Giovanni Benelli
Recent research in entomology and parasitology focused on the efficacy of green fabricated nanomaterials as novel insecticides. In this study, we synthesized poly-dispersed and stable silver nanoparticles (AgNPs) using the leaf extract of Holostemma ada-kodien. The nanostructures were characterized by ultraviolet-visible spectroscopy, Fourier-transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray, and X-ray diffraction analysis. The efficacy of H...
February 17, 2018: Journal of Photochemistry and Photobiology. B, Biology
Meiyu Gai, Maxim A Kurochkin, Danyang Li, Boris N Khlebtsov, Luo Dong, Nadja Tarakina, Robin Poston, David J Gould, Johannes Frueh, Gleb B Sukhorukov
Controlled drug delivery and gene expression is required for a large variety of applications including cancer therapy, wound healing, cell migration, cell modification, cell-analysis, reproductive and regenerative medicine. Controlled delivery of precise amounts of drugs to a single cell is especially interesting for cell and tissue engineering as well as therapeutics and has until now required the application of micro-pipettes, precisely placed dispersed drug delivery vehicles, or injections close to or into the cell...
March 7, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
Sushil Kumar Ranjan, Abhishek Kumar Soni, Vineet Kumar Rai
Frequency up-conversion (UC) emission from the Nd3+ -Yb3+ /Nd3+ -Yb3+ -Li+ co-doped gadolinium oxide (Gd2 O3 ) phosphors prepared by the solution combustion technique in the visible range have been studied by using 980 nm near infrared (NIR) laser diode excitation. The crystalline structure and formation of the cubic phase has been confirmed with the help of X-ray diffraction (XRD) studies. XRD peak shifts have been found towards the lower diffraction angle side in the case of the Nd3+ -Yb3+ -Li+ co-doped phosphors...
March 2, 2018: Luminescence: the Journal of Biological and Chemical Luminescence
Yong Tang, Hanguang Lu, Longshi Rao, Zongtao Li, Xinrui Ding, Caiman Yan, Binhai Yu
The ability to precisely obtain tunable spectrum of lead halide perovskite quantum dots (QDs) is very important for applications, such as in lighting and display. Herein, we report a microchannel reactor method for synthesis of CsPbBr₃ QDs with tunable spectrum. By adjusting the temperature and velocity of the microchannel reactor, the emission peaks of CsPbBr₃ QDs ranging from 520 nm to 430 nm were obtained, which is wider than that of QDs obtained in a traditional flask without changing halide component...
March 2, 2018: Materials
Wensong Li, Jiaji Wu, Xiaofeng Guan, Zhiyong Zhou, Huiying Xu, Zhengqian Luo, Zhiping Cai
In this work, efficient visible Ho3+ -doped fluorozirconate glass (Ho:ZBLAN) all-fiber lasers operating in continuous-wave (CW) and Q-switching regimes are experimentally demonstrated. The combination of a direct blue pump, a highly-doped Ho:ZBLAN fiber and the fiber end-facet mirrors contributes to a simple all-fiber configuration. A tunable laser emission in the green spectral range of 543-550 nm is achieved with >150 mW output power and a tunable deep-red laser around 754-758 nm is also obtained with about 16 mW output power...
March 2, 2018: Nanoscale
Robert Boge, Jakub Horáček, Petr Mazůrek, Jack A Naylon, Jonathan T Green, Zbyněk Hubka, Václav Šobr, Jakub Novák, František Batysta, Roman Antipenkov, Pavel Bakule, Bedřich Rus
A robust and simple method is presented for ensuring constant energy and pointing of a high average power solid state laser on a target. In addition to providing long-term stability, this scheme also eliminates any drifts in energy or pointing resulting from the initial warm-up after a cold start. This is achieved using two separate feedback loops: one loop stabilizes the pointing of the beam external to the amplifier cavity and the other locks the cavity mode to have optimum overlap with the pump spot on the active medium...
February 2018: Review of Scientific Instruments
Sunil Pandey, Krishna Hari Sharma, Amit Kumar Sharma, Yowan Nerthigan, Da-Ren Hang, Hui-Fen Wu
The present study deals with photothermal therapy of solid tumors using different forms oxygen deficient sub-stoichiometric two-dimensional (2D) molybdenum oxide nanoflakes (α-MoO3-x). Upon exfoliation of molybdenum oxide power using fine gridding followed by ultrasonication, bluish green molybdenum oxide (BG α-MoO3) was obtained. The oxygen vacancies in BG was generated by irradiating it using intense xenon lamp (600-900W, 200-1500nm) for 3-5 hours. Irradiating the BG for 3 and 5 hours, deep blue (B) and olive green (G) oxygen deficient nanoflakes were obtained respectively...
March 1, 2018: Chemistry: a European Journal
Yuwaraj Khatri Kshetri, Chhabilal Regmi, Hak Soo Kim, Soo Wohn Lee, Tae Ho Kim
Yb&lt;sup&gt;3+&lt;/sup&gt; and Er&lt;sup&gt;3+&lt;/sup&gt; doped YVO&lt;sub&gt;4&lt;/sub&gt; (Yb&lt;sup&gt;3+&lt;/sup&gt;/Er&lt;sup&gt;3+&lt;/sup&gt;:YVO&lt;sub&gt;4&lt;/sub&gt;) nanoparticles with highly efficient near-infrared to visible upconversion properties have been synthesized by microwave hydrothermal process. Uniform-sized Yb&lt;sup&gt;3+&lt;/sup&gt;/Er&lt;sup&gt;3+&lt;/sup&gt;:YVO&lt;sub&gt;4&lt;/sub&gt; nanoparticles were synthesized within 1 hour at 140˚C which is relatively faster than the conventional hydrothermal process...
February 28, 2018: Nanotechnology
Cennet Neslihan Eroglu, Serap Keskin Tunc, Remzi Erten, Aslıhan Usumez
BACKGROUND: Although antimicrobial efficacy of photodynamic therapy has been studied several times, there is no study investigating its efficacy on pericoronitis. This study aimed to determine whether antimicrobial photodynamic therapy combined with antibiotic therapy is clinically and histologically superior to antibiotic therapy alone in pericoronitis treatment. METHODS: Patients (n = 40) with pericoronitis were divided into two groups (20 patients for each) to receive either antibiotic + indocyanine green + 810 nm wavelength diode laser (antimicrobial photodynamic therapy group) or antibiotic alone...
February 24, 2018: Photodiagnosis and Photodynamic Therapy
Brenda J Green, Magdalini Panagiotakopoulou, Francesca Michela Pramotton, Georgios Stefopoulos, Shana O Kelley, Dimos Poulikakos, Aldo Ferrari
Invasion of dense tissues by cancer cells involves the interplay between the penetration resistance offered by interstitial pores and the deformability of cells. Metastatic cancer cells find optimal paths of minimal resistance through an adaptive path-finding process, which leads to successful dissemination. The physical limit of nuclear deformation is related to the minimal cross section of pores that can be successfully penetrated. However, this single biophysical parameter does not fully describe the architectural complexity of tissues featuring pores of variable area and shape...
February 26, 2018: Nano Letters
Henry L Feng, Sumit Sharma, Sandra Stinnett, Sanjay Asrani, Prithvi Mruthyunjaya
PURPOSE: To assess posterior segment findings on multicolor confocal scanning laser ophthalmoscopy by correlation with spectral domain optical coherence tomography (SD-OCT) and to quantify agreement between these imaging modalities. METHODS: Retrospective review of 159 eyes of 96 consecutive patients who underwent concurrent imaging with multicolor confocal scanning laser ophthalmoscopy and SD-OCT. Positive percent agreement and negative percent agreement were calculated for each finding identified on infrared, green, blue, and multicolor reflectance images using SD-OCT as a comparator...
February 22, 2018: Retina
Manuela Rebora, Jan Michels, Gianandrea Salerno, Lars Heepe, Elena Gorb, Stanislav Gorb
Based on analyses with cryo-scanning and transmission electron microscopy, the present study reports on the morphology and ultrastructure of the attachment structures of the green stinkbug Nezara viridula L. (Heteroptera: Pentatomidae), a cosmopolitan pest of different crops in most areas of the world. In addition, the presence and distribution of large proportions of the elastic protein resilin in these structures was revealed by confocal laser scanning microscopy. The attachment structures of each leg comprise two sclerotised claws, a pair of smooth flexible pulvilli and a hairy adhesive pad located at the ventral side of the basitarsus...
February 21, 2018: Journal of Morphology
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