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https://www.readbyqxmd.com/read/29044433/pregnancy-induced-changes-in-metabolome-and-proteome-in-ovine-uterine-flushings
#1
Jared J Romero, Bethany E Liebig, Corey D Broeckling, Jessica E Prenni, Thomas R Hansen
Mass spectrometry (MS) approaches were used herein to identify metabolites and proteins in uterine flushings (UF) that may contribute to nourishing the conceptus. Ovine uteri collected on Day 12 of the estrous cycle (n = 5 ewes exposed to vasectomized ram) or Days 12 (n = 4), 14 (n = 5), or 16 (n = 5) of pregnancy (bred with fertile ram) were flushed using buffered saline. Metabolites were extracted using 80% methanol and profiled using ultraperformance liquid chromatography (LC) tandem mass spectrometry. The proteome was examined by digestion with trypsin, followed by the analysis of peptides with LC-MS/MS...
August 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29044000/observation-on-shenqi-fuzheng-injection-combined-with-cefoxitin-sodium-after-cesarean-section
#2
Jingge Chen, Yumin Cheng, Xinxiang Ma, Yuanyuan Cao
This paper aims to observe the effect of Shenqi Fuzheng Injection combined with cefoxitin sodium after cesarean section. Clinical data of 126 puerperae were retrospectively analyzed. They randomized into control group and treatment group, and there were 63 cases in each group. Patients in control group were given Cefoxitin Sodium treatment. And patients in treatment group were given Shenqi Fuzheng Injection on the basis of control group. After 7 days of treatment, the clinical curative effect of the two groups was observed and compared...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29043712/uterus-dysplasia-associated-with-cervico-vaginal-agenesis
#3
Ali Mahdavi, Hadi Mirfazaelian, Ladan Younesi Asl, Zeynab Hasani, Maryam Bahreini
Müllerian ducts can form upper parts of normal female reproductive system and any failure in ductal fusion may result in to müllerian duct anomalies (MDA). We present a case of MDA and a uterus dysplasia with no evidence of cervical or upper vaginal tissue. This case showes the role of magnetic resonace imaging (MRI) on MDA diagnosis and urges the need for a unified reliable and practical classification more compatible with clinical practice.
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043710/pregnancy-in-non-communicating-rudimentary-horn-of-a-unicornuate-uterus
#4
Mania Kaveh, Abolfazl Mehdizadeh Kashi, Kambiz Sadegi, Forough Forghani
Diagnosis and management of pre-rupture stage of the pregnant horn are difficult and usually missed on a routine ultrasound scan. Also most cases are detected after rupture of pregnant horn. We presented a 28-year-oldG2 L1 woman with diagnosis of rudimentary horn pregnancy (RHP) at 14 weeks of gestation. We diagnosed her with a normal intrauterine pregnancy, whereas a pregnancy in a right-sided non-communicating rudimentary horn with massive hemoperitoneum was later discovered on laparotomy. RHP has a high risk of death for mother, so there must be a strong clinical suspicion for the diagnosis of RHP...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043704/accuracy-of-two-dimensional-transvaginal-sonography-and-office-hysteroscopy-for-detection-of-uterine-abnormalities-in-patients-with-repeated-implantation-failures-or-recurrent-pregnancy-loss
#5
Marzieh Shiva, Firouzeh Ahmadi, Arezoo Arabipoor, Mansoureh Oromiehchi, Mohammad Chehrazi
Background: We sought to compare diagnostic values of two-dimensional transvaginal sonography (2D TVS) and office hysteroscopy (OH) for evaluation of endometrial pathologies in cases with repeated implantation failure (RIF) or recurrent pregnancy loss (RPL). MATERIALS AND METHODS: This prospective study was performed at Royan Institute from December 2013 to January 2015. TVS was performed before hysteroscopy as part of the routine diagnostic work-up in 789 patients with RIF or RPL...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29042974/curative-effect-of-laparoscopic-hysterectomy-for-uterine-fibroids-and-its-impact-on-ovarian-blood-supply
#6
Xing Wang, Li Lv, Zhiyong Cheng, Xuewu Zhou
This study evaluates the curative effects laparo-scopic hysterectomies performed to treat uterine fibroids and determined the impact of the procedures on ovarian blood supply. A total of 124 patients with uterine fibroids admitted and treated in our hospital from December 2014 to December 2015 participated in the study. Two groups of 62 patients each were formed according to different operating plans; one group of patients underwent abdominal (open) panhysterectomy and were set as the control group; with the other group of patients were treated with laparoscopic hysterectomy and were set as the observation group...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29042600/dynamic-and-modularized-microrna-regulation-and-its-implication-in-human-cancers
#7
Jiang Shu, Bruno Vieira Resende E Silva, Tian Gao, Zheng Xu, Juan Cui
MicroRNA is responsible for the fine-tuning of fundamental cellular activities and human disease development. The altered availability of microRNAs, target mRNAs, and other types of endogenous RNAs competing for microRNA interactions reflects the dynamic and conditional property of microRNA-mediated gene regulation that remains under-investigated. Here we propose a new integrative method to study this dynamic process by considering both competing and cooperative mechanisms and identifying functional modules where different microRNAs co-regulate the same functional process...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29042534/the-microbiota-continuum-along-the-female-reproductive-tract-and-its-relation-to-uterine-related-diseases
#8
Chen Chen, Xiaolei Song, Weixia Wei, Huanzi Zhong, Juanjuan Dai, Zhou Lan, Fei Li, Xinlei Yu, Qiang Feng, Zirong Wang, Hailiang Xie, Xiaomin Chen, Chunwei Zeng, Bo Wen, Liping Zeng, Hui Du, Huiru Tang, Changlu Xu, Yan Xia, Huihua Xia, Huanming Yang, Jian Wang, Jun Wang, Lise Madsen, Susanne Brix, Karsten Kristiansen, Xun Xu, Junhua Li, Ruifang Wu, Huijue Jia
Reports on bacteria detected in maternal fluids during pregnancy are typically associated with adverse consequences, and whether the female reproductive tract harbours distinct microbial communities beyond the vagina has been a matter of debate. Here we systematically sample the microbiota within the female reproductive tract in 110 women of reproductive age, and examine the nature of colonisation by 16S rRNA gene amplicon sequencing and cultivation. We find distinct microbial communities in cervical canal, uterus, fallopian tubes and peritoneal fluid, differing from that of the vagina...
October 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29041834/quality-assessment-of-the-detailed-anomaly-ultrasound-scan
#9
Athena P Souka, Athanasios Pilalis, Ioannis Papastefanou, Makarios Eleftheriadis, George Papadopoulos
OBJECTIVES: The objective of this study is to assess the quality of the views in the detailed anomaly ultrasound scan and examine the parameters that influence it. METHODS: Prospective study on singleton pregnancies examined at 20-24 weeks. Detailed views of all fetal organs were classified by the examiner as optimal/suboptimal. The duration of the examination was observed. Maternal characteristics, Fat Index (FI) (distance between the skin and the surface of the uterus), and fetal position were recorded...
October 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29040880/prolonged-parturition-and-impaired-placenta-expulsion-increase-the-risk-of-postpartum-metritis-and-delay-uterine-involution-in-sows
#10
S Björkman, C Oliviero, J Kauffold, N M Soede, O A T Peltoniemi
It was hypothesized that prolonged parturition and impaired placenta expulsion increase the risk of postpartum metritis and delay uterine involution. At parturition, for 99 Yorkshire x Large White sows (parity 2-5), we determined the number of liveborn (NLP; 14.8 ± 3.4) and stillborn piglets (NSP; 1.1 ± 1.1), farrowing duration (FAR, time between first and last piglet; 333 ± 249 min), placenta expulsion duration (PLA, time between first and last placental part; 292 ± 241 min) and number of expelled placental parts (PART; 3...
October 7, 2017: Theriogenology
https://www.readbyqxmd.com/read/29040191/incidence-patterns-and-survival-of-gynecological-sarcoma-in-germany-analysis-of-population-based-cancer-registry-data-on-1066-women
#11
Klaus Pietzner, Nina Buttmann-Schweiger, Jalid Sehouli, Klaus Kraywinkel
OBJECTIVE: Sarcomas of the female genital tract are rare tumors. They are described to be associated with a poor prognosis when compared with gynecogical carcinoma. The aim of this study was to report incidence patterns and survival rates for gynecological sarcoma (GS) in Germany. METHODS/MATERIALS: Clinical data and survival rates for patients with GS diagnosed in Germany between 2009 and 2013 were extracted from the German national center for population-based cancer registry data...
October 17, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29039288/molecular-and-morphological-characterization-of-belondira-coomansi-n-sp-nematoda-dorylaimida-belondiridae-from-iran
#12
B Golhasan, R Heydari, E Miraeiz, J Abolafia, R Peña-Santiago
A new species belonging to the genus Belondira is described from natural areas in Iran. Belondira coomansi n. sp. is characterized by its general size, the dimensions and appearance of its lip region, presence of distinct labial and post-labial sclerotization, the length of the odontostyle and its inconspicuous lumen and aperture, the length of the neck and its pharyngeal expansion, the reduction of the female anterior genital branch to a simple uterine sac, a very short posterior uterus, the anterior position of the vulva, the length and shape of the caudal region with distinctly thick cuticle at its tip, the length of the spicules, and the presence of only one pair of ventromedian supplements...
October 17, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/29038843/per-oral-endoscopic-salpingo-oophorectomy-poesy-in-humans-a-prospective-clinical-feasibility-study
#13
Amadeus Hornemann, Marc Suetterlin, Georg Kaehler
BACKGROUND AND AIMS: Natural orifice translumenal endoscopic surgery (NOTES) procedure describes a surgical approach using natural orifices. We describe a prospective non-comparative clinical study on transgastric salpingo-oophorectomy in humans. METHODS: Patients with indication for salpingo-oophorectomy were offered the transgastric approach. This paper presents the data of the first 6 patients, in whom the procedure was performed. After gastroscopic incision in the anterior corpus wall we advanced the flexible gastroscope into the abdominal cavity...
October 16, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29038039/hysteroscopic-transcervical-resection-for-atypical-polypoid-adenomyoma-of-the-uterus-a-valid-fertility-preserving-option
#14
Tatsuyuki Chiyoda, Bao-Liang Lin, Keiko Saotome, Shunki Kiyokawa, Sakura Nakada
STUDY OBJECTIVE: To evaluate hysteroscopic transcervical resection (TCR) for atypical polypoid adenomyoma of the uterus (APA). DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Single tertiary hospital. PATIENTS: Women who underwent TCR for APA at Kawasaki Municipal Hospital between 2003 and 2015. INTERVENTIONS: Clinical records were obtained. MEASUREMENTS AND MAIN RESULTS: Thirty-five APA cases were evaluated...
October 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29037554/the-role-of-resveratrol-on-full-thickness-uterine-wound-healing-in-rats
#15
Oya Sayin, Serap Cilaker Micili, Asli Goker, Gonca Kamaci, Bekir Ugur Ergur, Osman Yilmaz, Gul Guner Akdogan
OBJECTIVE: Healing of the uterus after cesarean section and myomectomy operation is clinically important. In this study, we aimed to investigate the effects of resveratrol (3,5,4'-o-trihydroxystilbene) on the wound healing process of the uterus in rats treated with resveratrol following full thickness injury of the uterus. MATERIALS AND METHODS: Twenty-one female wistar albino rats were divided randomly into three groups (1) control group with no intervention (2) injury group with uterine full thickness injury (3) resveratrol group with uterine full thickness injury and treated with resveratrol...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29037192/retroperitoneal-ectopic-pregnancy-a-case-report-and-review-of-the-literature
#16
Man Yang, Lamu Cidan, Dan Zhang
BACKGROUND: Retroperitoneal ectopic pregnancy (REP) is an extremely rare type of ectopic pregnancy, with a total of less than 20 cases reported in the English literature. However, failure to recognize REP may result in severe consequences. CASE PRESENTATION: We report a case of 32-year-old woman with REP. She had amenorrhea, left lower abdominal pain, but no vaginal bleeding. Her urine human chorionic gonadotropin (HCG) test was positive and blood HCG level was 1880 m-international units per milliliter (mIU/mL)...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29037132/expression-of-hormonal-carcinogenesis-genes-and-related-regulatory-micrornas-in-uterus-and-ovaries-of-ddt-treated-female-rats
#17
T S Kalinina, V V Kononchuk, L F Gulyaeva
The insecticide dichlorodiphenyltrichloroethane (DDT) is a nonmutagenic xenobiotic compound able to exert estrogen-like effects resulting in activation of estrogen receptor-α (ERα) followed by changed expression of its downstream target genes. In addition, studies performed over recent years suggest that DDT may also influence expression of microRNAs. However, an impact of DDT on expression of ER, microRNAs, and related target genes has not been fully elucidated. Here, using real-time PCR, we assessed changes in expression of key genes involved in hormonal carcinogenesis as well as potentially related regulatory oncogenic/tumor suppressor microRNAs and their target genes in the uterus and ovaries of female Wistar rats during single and chronic multiple-dose DDT exposure...
October 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/29037097/obstetrical-and-neonatal-outcomes-of-pregnancies-complicated-by-endometriosis
#18
Anat Shmueli, Lina Salman, Liran Hiersch, Eran Ashwal, Eran Hadar, Arnon Wiznitzer, Yariv Yogev, Amir Aviram
OBJECTIVE: Endometriosis is defined as the presence of endometrial-like tissue outside the uterus, associated with pelvic pain and subfertility, affecting 0.6-10% of the general female population. The association between endometriosis and obstetrical outcomes is not well established. We aimed to evaluate whether endometriosis is associated with a higher incidence of obstetrical and neonatal complications. STUDY DESIGN: A retrospective cohort study of all deliveries in a university-affiliated tertiary hospital (2007-2014)...
October 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29035998/uterine-metastasis-from-gastric-adenocarcinoma-masquerading-as-physiologic-endometrial-uptake-in-fdg-pet-ct
#19
Yutang Yao, Minggang Su, Xiaohong Ou, Yangmei Shen
A 44-year-old woman with newly diagnosed gastric adenocarcinoma by gastroscopy underwent F-FDG PET/CT to evaluate possible metastasis. The images demonstrated intense activity in the region of uterine corpus, as well as greater gastric curvature. Physiologic uptake of endometrium was initially suspected, given the rarity with which extragenital cancers metastasize to the uterus. Ultimately, the endometrium proved to be mucinous adenocarcinoma of gastric origin based on its shared histological features and compatible immunostaining profile...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035853/the-gastrointestinal-nematodes-of-paramelomys-lorentzii-and-mammelomys-spp-rodentia-muridae-with-descriptions-of-a-new-genus-and-three-new-species-heligmonellidae-from-papua-new-guinea-and-indonesia
#20
Lesley R Smales
Unidentified cestodes and 14 species of nematode and larvae that could not be placed to family level, were collected from the digestive tracts of 27 individuals of Paramelomys lorentzii, four of Mammelomys lanosus and a single M. rattoides from Papua New Guinea and Papua Indonesia. Of these three were new species. Hughjonestrongylus woolleyae sp. nov. can be distinguished from its congeners in having up to 26 ridges in the synlophe and a dissymmetric dorsal ray. Parvinema bafunminensis gen. nov., sp. nov. can be distinguished from all other genera in the family by the combination of features in the synlophe; with a carene, up to 17 ridges, and the pattern of ridge sizes...
December 20, 2017: Acta Parasitologica
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