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https://www.readbyqxmd.com/read/28633999/characteristics-of-a-mild-traumatic-brain-injury-sample-recruited-using-amazon-s-mechanical-turk
#1
John Bernstein, Matthew Calamia
BACKGROUND: Several barriers exist in the recruitment of individuals with a history of mild traumatic brain injury (mTBI). The current study is the first to examine whether crowdsourcing, which has been used in other clinical populations, is useful in the recruitment of those with mTBI. OBJECTIVE: To examine whether Amazon's Mechanical Turk (MTurk), an online crowdsourcing platform, is a useful tool in the recruitment of individuals with a history of mild traumatic brain injury (mTBI) and to examine the injury and psychological characteristics of individuals who report a history of mTBI...
June 17, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28627275/the-effects-of-exercise-on-patient-reported-outcomes-and-performance-based-physical-function-in-adults-with-acute-leukemia-undergoing-induction-therapy
#2
Ashley Leak Bryant, Allison M Deal, Claudio L Battaglini, Brett Phillips, Mackenzi Pergolotti, Erin Coffman, Matthew C Foster, William A Wood, Charlotte Bailey, Anthony C Hackney, Deborah K Mayer, Hyman B Muss, Bryce B Reeve
INTRODUCTION: Fatigue is a distressing symptom for adults with acute leukemia, often impeding their ability to exercise. OBJECTIVES: 1) Examine effects of a 4-week mixed-modality supervised exercise program (4 times a week, twice a day) on fatigue in adults with acute leukemia undergoing induction chemotherapy. 2) Evaluate effects of exercise program on cognition, anxiety, depression, and sleep disturbance. 3) Evaluate effect of intervention on adherence to exercise...
March 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28623892/improving-transitions-in-acute-stroke-patients-discharged-to-home-the-michigan-stroke-transitions-trial-mistt-protocol
#3
Mathew J Reeves, Anne K Hughes, Amanda T Woodward, Paul P Freddolino, Constantinos K Coursaris, Sarah J Swierenga, Lee H Schwamm, Michele C Fritz
BACKGROUND: For some stroke patients and caregivers, navigating the transition between hospital discharge and returning home is associated with substantial psychosocial and health-related challenges. Currently, no evidence-based standard of care exists that addresses the concerns of stroke patients and caregivers during the transition period. Objectives of the Michigan Stroke Transitions Trial (MISTT) are to test the impact of a social worker home-based case management program, as well as an online information and support resource, on patient and caregiver outcomes after returning home...
June 17, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28618668/re-diagnostic-accuracy-of-multi-parametric-mri-and-trus-biopsy-in-prostate-cancer-promis-a-paired-validating-confirmatory-study
#4
Samir S Taneja
No abstract text is available yet for this article.
July 2017: Journal of Urology
https://www.readbyqxmd.com/read/28609640/assessment-of-disability-related-to-femoroacetabular-impingement-syndrome-by-use-of-the-patient-reported-outcome-measure-information-system-promis-and-objective-measures-of-physical-performance
#5
Andrew J Sheean, Matthew R Schmitz, Catherine L Ward, Aaron E Barrow, David J Tennent, Christopher J Roach, Travis C Burns, Jason M Wilken
BACKGROUND: The National Institutes of Health (NIH)-sponsored Patient-Reported Outcomes Measurement System (PROMIS) has been described as a valuable tool for characterizing outcomes among patients with specific musculoskeletal conditions. Additionally, previously proposed objective measures of physical performance among patients with nonarthritic hip abnormalities are costly and not practically incorporated into routine clinical practice. PURPOSE: (1) To determine the ability of the PROMIS to differentiate between patients with femoroacetabular impingement (FAI) and asymptomatic controls, (2) to determine the effect of FAI on subjects' completion of timed physical performance measures, and (3) to determine whether associations exist between established patient-reported outcome (PRO) measures and subjects' completion of physical performance measures...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28606686/adults-with-an-epilepsy-history-fare-significantly-worse-on-positive-mental-and-physical-health-than-adults-with-other-common-chronic-conditions-estimates-from-the-2010-national-health-interview-survey-and-patient-reported-outcome-measurement-system-promis
#6
Rosemarie Kobau, Wanjun Cui, Matthew M Zack
Healthy People 2020, a national health promotion initiative, calls for increasing the proportion of U.S. adults who self-report good or better health. The Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Scale (GHS) was identified as a reliable and valid set of items of self-reported physical and mental health to monitor these two domains across the decade. The purpose of this study was to examine the percentage of adults with an epilepsy history who met the Healthy People 2020 target for self-reported good or better health and to compare these percentages to adults with history of other common chronic conditions...
June 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28604084/an-initial-psychometric-evaluation-of-the-german-promis-v1-2-physical-function-item-bank-in-patients-with-a-wide-range-of-health-conditions
#7
Gregor Liegl, Matthias Rose, Helena Correia, H Felix Fischer, Sibel Kanlidere, Annett Mierke, Alexander Obbarius, Sandra Nolte
OBJECTIVES: To translate the PROMIS Physical Function (PF) item bank version 1.2 into German and to investigate psychometric properties of resulting full bank and seven derived short forms. DESIGN: Cross-sectional psychometric study. SETTING: Inpatient and outpatient clinics of the Department of Psychosomatic Medicine at Charité-Universitätsmedizin Berlin, Germany. SUBJECTS: A total of 10 adult patients with various chronic diseases participated in cognitive debriefing interviews...
June 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28599626/factors-associated-with-general-practitioners-awareness-of-depression-in-primary-care-patients-with-heart-failure-baseline-results-from-the-observational-recode-hf-study
#8
Marion Eisele, Anja Rakebrandt, Sigrid Boczor, Agata Kazek, Nadine Pohontsch, Magdalena Okolo-Kulak, Eva Blozik, Jens-Martin Träder, Stefan Störk, Christoph Herrmann-Lingen, Martin Scherer
BACKGROUND: Depression is more prevalent in patients with heart failure (HF) than in those without, but its detection is complicated by the symptom overlap between the two diseases. General practitioners (GPs) are the first point of contact for patients with HF. Therefore, this study aims to investigate GPs' awareness of depression in their HF patients and factors associated with this awareness. METHODS: In this cross-sectional, observational study 3224 primary care patients with HF were screened for depressive symptomatology using an algorithm based on the Hospital Anxiety and Depression Scale, the 9-item subscale on Depression of the Patient Health Questionnaire, and selected items from the PROMIS Depression and Anxiety scales...
June 9, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28590381/performance-of-promis-for-healthy-patients-undergoing-meniscal-surgery
#9
Kyle J Hancock, Natalie Glass, Chris A Anthony, Carolyn M Hettrich, John Albright, Annunziato Amendola, Brian R Wolf, Matthew Bollier
BACKGROUND: The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed as an extensive question bank with multiple health domains that could be utilized for computerized adaptive testing (CAT). In the present study, we investigated the use of the PROMIS Physical Function CAT (PROMIS PF CAT) in an otherwise healthy population scheduled to undergo surgery for meniscal injury with the hypotheses that (1) the PROMIS PF CAT would correlate strongly with patient-reported outcome instruments that measure physical function and would not correlate strongly with those that measure other health domains, (2) there would be no ceiling effects, and (3) the test burden would be significantly less than that of the traditional measures...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28587919/patient-reported-outcome-measurement-system-promis-%C3%A2-pain-intensity-and-pain-interference-in-patients-with-urolithiasis-initial-report
#10
Michael S Borofsky, Giulia I Lane, Suzanne M Neises, Andrew J Portis
INTRODUCTION: Health related quality-of-life is increasingly important in quality improvement efforts for medical conditions but has proved challenging to measure for urolithiasis given the distinct chronic and acute phases of this disease. We evaluated the utility of using the Patient-Reported Outcomes Measurement System (PROMIS(®)) to assess patient experience through stages of the acute stone episode. MATERIALS AND METHODS: PROMIS(®) pain measures (intensity and interference) were obtained from patients at a subspecialty kidney stone clinic...
June 3, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28581685/voices-of-children-and-adolescents-on-phase-1-or-phase-2-cancer-trials-a-new-trial-endpoint
#11
Pamela S Hinds, Jichuan Wang, Emily Dunn Stern, Catherine Fiona Macpherson, Claire M Wharton, Ruthanna Okorosobo, Yao Iris Cheng, Heather E Gross, Holly J Meany, Shana Jacobs
BACKGROUND: Pediatric participants on phase 1 or phase 2 clinical trials for incurable cancer are at risk of experiencing toxicities (adverse events [AEs]) related to trial participation. Multiple AEs are subjective; thus, the real impact of trial treatment cannot be known unless patient subjective reports are solicited. METHODS: The authors assessed the feasibility and acceptability of soliciting symptom, function, and quality of life (QOL) reports from participants aged 8 to 18 years who were enrolled on phase 1/2 clinical trials at 4 cancer centers during the first course of chemotherapy...
June 5, 2017: Cancer
https://www.readbyqxmd.com/read/28578579/simple-and-efficient-generation-of-aryl-radicals-from-aryl-triflates-synthesis-of-aryl-boronates-and-aryl-iodides-at-room-temperature
#12
Wenbo Liu, Xiaobo Yang, Yang Gao, Chao-Jun Li
Despite the wide use of aryl radicals in organic synthesis, current methods to prepare them from aryl halides, carboxylic acids, boronic acids, and diazonium salts suffer from limitations. Aryl triflates, easily obtained from phenols, are promising aryl radical progenitors but remain elusive in this regard. Inspired by the single electron transfer process for aryl halides to access aryl radicals, we developed a simple and efficient protocol to convert aryl triflates to aryl radicals. Our success lies in exploiting sodium iodide as the soft electron donor assisted by light...
June 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28578534/instruments-to-measure-anxiety-in-children-adolescents-and-young-adults-with-cancer-a-systematic-review
#13
REVIEW
Tanya Lazor, Leonie Tigelaar, Jason D Pole, Claire De Souza, Deborah Tomlinson, Lillian Sung
PURPOSE: The primary objective was to describe anxiety measurement instruments used in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation (HSCT) and summarize their content and psychometric properties. METHODS: We conducted searches of MEDLINE, Embase, PsycINFO, HAPI, and CINAHL. We included studies that used at least one instrument to measure anxiety quantitatively in children or adolescents with cancer or undergoing HSCT...
June 3, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28577684/electronically-self-assessed-functional-capacity-and-exercise-testing-a-comparison-of-the-duke-activity-status-index-and-patient-reported-outcomes-measurement-information-system-tools
#14
Ryan A Coute, Jesse M Ehrenfeld, Deepak K Gupta, Maxim A Terekhov, Jonathan P Wanderer
PURPOSE: Electronic screening tools, such as Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function Short-Form 12a (PF-SF12a), may aid in the assessment of functional capacity. However, PROMIS PF-SF12a has not been validated against exercise capacity, or compared with established questionnaires, including the Duke Activity Status Index (DASI). We compared the DASI and PROMIS PF-SF12a to the maximum metabolic equivalents (METs) achieved during exercise stress testing...
June 2017: American Heart Journal
https://www.readbyqxmd.com/read/28577358/sensitivity-of-alternative-measures-of-functioning-and-wellbeing-for-adults-with-sickle-cell-disease-comparison-of-promis%C3%A2-to-ascq-me%C3%A2
#15
San Keller, Manshu Yang, Marsha J Treadwell, Kathryn L Hassell
BACKGROUND: Sickle Cell Disease (SCD) causes profound suffering and decrements in daily functioning. Demand is growing for valid and reliable measures to systematically document these effects, particularly in adults. The Adult Sickle Cell Quality of Life Measurement System, ASCQ-Me℠, was developed for this purpose. ASCQ-Me℠ is one of four measurement systems housed within the Person-Centered Assessment Resource (PCAR), funded by the National Institutes of Health, to support clinical research...
June 2, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28573045/danish-translation-of-a-physical-function-item-bank-from-the-patient-reported-outcome-measurement-information-system-promis
#16
Christina W Schnohr, Charlotte L Rasmussen, Henning Langberg, Jakob B Bjørner
BACKGROUND: The Patient-Reported Outcome Measurement Information System (PROMIS) is an assessment system that aims to provide more valid, reliable, responsive, and precise patient-reported outcome (PRO) measures than has been previously available. This paper documents the translation of the Physical Function item bank into Danish. METHODS: We followed the PROMIS standard procedure, including: 1) two independent translations, 2) back translation, 3) independent reviews of translation quality, and 4) cognitive interviews with a representative sample of the adult population from the municipality of Copenhagen...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28566193/efficacy-of-transcranial-direct-current-stimulation-over-primary-motor-cortex-anode-and-contralateral-supraorbital-area-cathode-on-clinical-pain-severity-and-mobility-performance-in-persons-with-knee-osteoarthritis-an-experimenter-and-participant-blinded-randomized
#17
Hyochol Ahn, Adam J Woods, Mark E Kunik, Abhishek Bhattacharjee, Zhiguo Chen, Eunyoung Choi, Roger B Fillingim
BACKGROUND: Previous studies indicate that transcranial direct current stimulation (tDCS) with anode over motor cortex (M1) and cathode over contralateral supraorbital region (SO) may be effective in reducing pain, but these studies are limited in number and have not focused on older adults with osteoarthritis (OA). OBJECTIVE: To evaluate the preliminary efficacy and safety of M1-SO applied tDCS on clinical pain severity and mobility performance in adults with knee OA pain...
May 19, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28564743/forced-retirement-from-professional-rugby-union-is-associated-with-symptoms-of-distress
#18
James Craig Brown, Gino Kerkhoffs, Mike I Lambert, Vincent Gouttebarge
Rugby has a higher injury burden than other popular sports, such as football. Athletes who are forced to retire as a result of injury are associated with poor mental health. With its high injury burden, professional rugby players might be at risk of mental health conditions associated with injury-related forced retirement. This study aimed to compare mental health between former professional rugby players who were and weren't forced to retire. A questionnaire including the 4DSQ (distress), GHQ-12 (anxiety/depression), PROMIS short-form (sleep disturbance) and AUDIT-C (alcohol misuse) was completed by retired professional players from Ireland, France and South Africa...
May 31, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28551577/bioactive-growth-hormone-in-older-men-and-women-it-s-relationship-to-immune-markers-and-healthspan
#19
William J Kraemer, Mary J Kennett, Andrea M Mastro, Roger J McCarter, Connie J Rogers, William H DuPont, Shawn D Flanagan, William J Turbitt, Maren S Fragala, Emily M Post, Wesley C Hymer
OBJECTIVE: The consequences of age-related decline in the somatotropic axis of humans are complex and remain largely unresolved. We tested the hypothesis that hGH measurements of plasma by bioassay vs immunoassay from samples obtained from free-living, elderly individuals would reveal a dichotomy in GH activities that are correlated with the functional status of the donors, i.e. their healthspan. DESIGN: Forty-one men and women of advanced age (men: N=16, age, 80...
June 2017: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28516877/validity-of-the-workers-productivity-and-activity-impairment-questionnaire-specific-health-problem-wpai-shp-in-patients-with-systemic-sclerosis
#20
Kathleen Morrisroe, Wendy Stevens, Molla Huq, Joanne Sahhar, Gene-Siew Ngian, Jane Zochling, Janet Roddy, Susanna M Proudman, Mandana Nikpour
OBJECTIVES: To evaluate the construct validity of the Workers Productivity and Impairment Activity Index: Specific Health Problem (WPAI:SHP) in Australian systemic sclerosis (SSc) patients. METHODS: SSc patients, identified through the Australian Scleroderma Cohort Study database, completed the WPAI:SHP and a quality of life instrument (PROMIS-29) cross-sectionally. The construct validity of the WPAI:SHP was assessed by the correlations between the WPAI:SHP and a range of SSc health states...
May 8, 2017: Clinical and Experimental Rheumatology
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