Osamu Nagata, Yuka Matsuki, Shuko Matsuda, Keita Hazama, Saiko Fukunaga, Hideki Nakatsuka, Fumiyo Yasuma, Yasuhiro Maehara, Shoko Fujioka, Karin Tajima, Ichiro Kondo, Itaru Ginoza, Misuzu Hayashi, Manabu Kakinohana, Kenji Shigemi
BACKGROUND: We previously developed an automated total intravenous anesthesia control system that uses new closed-loop system algorithms to administer propofol, remifentanil, and rocuronium based on the bispectral index and train-of-four data. We recently improved this automated control system by adding a safety mechanism and using a modified monitoring device. METHODS: Patients scheduled for elective surgery were randomly assigned to closed-loop feedback control (automatic group) or the manual administration of propofol, remifentanil, and rocuronium (manual group)...
October 19, 2023: Journal of Clinical Medicine