keyword
MENU ▼
Read by QxMD icon Read
search

IVCM

keyword
https://www.readbyqxmd.com/read/29193851/survival-of-corneal-nerve-sheath-structures-in-organ-cultured-donor-corneas
#1
Virinder K Dhillon, Mohamed S Elalfy, Marco Messina, Mouhamed Al-Aqaba, Harminder S Dua
PURPOSE: To study the morphology of human corneal nerves in eye bank organ-cultured corneas and in corneal grafts post-transplantation. METHODS: Thirty-seven organ-cultured corneas were divided into: Group-A, anterior 300-400 μm of 20 corneas used for Descemets stripping endothelial keratoplasty, and Group-B, 17 full-thickness corneas unsuitable for transplantation. Corneas whole mounts were stained for nerves using acetylcholinesterase technique and examined by NanoZoomer digital pathology microscope...
November 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29176786/in-vivo-imaging-of-palisades-of-vogt-in-dry-eye-versus-normal-subjects-using-en-face-spectral-domain-optical-coherence-tomography
#2
Wajdene Ghouali, Rachid Tahiri Joutei Hassani, Zoubir Djerada, Hong Liang, Mohamed El Sanharawi, Antoine Labbé, Christophe Baudouin
PURPOSE: To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients. PATIENTS AND METHODS: Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT...
2017: PloS One
https://www.readbyqxmd.com/read/29135602/ocular-surface-alterations-in-the-context-of-corneal-in-vivo-confocal-microscopic-characteristics-in-patients-with-fibromyalgia
#3
Kadriye Erkan Turan, Sibel Kocabeyoglu, Isin Unal-Cevik, Figen Bezci, Aysen Akinci, Murat Irkec
PURPOSE: To quantify the morphology of corneal basal epithelium and subbasal nerves and to evaluate the ocular surface alterations in patients with fibromyalgia (FM). METHODS: Patients with FM (n = 34) and healthy controls (n = 42) were enrolled. All participants underwent ocular surface tests in the following order: corneal sensitivity, tear film breakup time, lissamine green staining, Schirmer test, and the Ocular Surface Disease Index questionnaire. Basal epithelial cells and subbasal nerves were evaluated using in vivo confocal microscopy (IVCM)...
November 9, 2017: Cornea
https://www.readbyqxmd.com/read/29133179/stage-related-central-corneal-epithelial-transformation-in-congenital-aniridia-associated-keratopathy
#4
Neil Lagali, Bogumil Wowra, Dariusz Dobrowolski, Tor Paaske Utheim, Per Fagerholm, Edward Wylegala
PURPOSE: To relate central corneal epithelial phenotype to degree of keratopathy in a limbal stem cell deficient population. METHODS: 37 patients (67 eyes) with aniridia-associated keratopathy (AAK) underwent corneal examination including slit lamp biomicroscopy to determine the Grade of AAK, Cochet-Bonnet esthesiometry, and in vivo confocal microscopy (IVCM) to assess morphology of the central corneal epithelium and subepithelial region. RESULTS: AAK Grade ranged from 1 (limbal involvement only) to 4 (total conjunctivalisation), with progression from Grade 1 occurring after the age of 20...
November 10, 2017: Ocular Surface
https://www.readbyqxmd.com/read/29129651/dendritic-cells-in-the-cornea-during-herpes-simplex-viral-infection-and-inflammation
#5
REVIEW
Min S Kwon, Nicole A Carnt, Naomi R Truong, Ushasree Pattamatta, Andrew J White, Chameen Samarawickrama, Anthony L Cunningham
Herpes simplex keratitis is commonly caused by Herpes simplex Virus Type 1 (HSV-1), which primarily infects eyelids, corneas or conjunctiva. HSV-1- through sophisticated interactions with dendritic cells (DCs), a type of antigen-presenting cell)-initiates pro-inflammatory responses in the cornea. Corneas were once thought to be an immune privileged region; however, with the recent discovery of DCs that reside in the cornea, this long held conjecture has been overturned. Therefore, evaluating the clinical, preclinical, and cell-based studies that investigate the roles of DCs in corneas infected with HSV is critical...
November 9, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29101151/laser-scanning-in-vivo-confocal-microscopy-ivcm-for-evaluating-human-corneal-sub-basal-nerve-plexus-parameters-protocol-for-a-systematic-review
#6
Manikkuwadura Eranda Harshan De Silva, Alexis Ceecee Zhang, Amalia Karahalios, Holly Rose Chinnery, Laura Elizabeth Downie
INTRODUCTION: Laser scanning in vivo confocal microscopy (IVCM) enables non-invasive, high-resolution imaging of the cornea. In recent years, there has been a vast increase in researchers using laser scanning IVCM to image and quantify corneal nerve parameters. However, a range of methodological approaches have been adopted. The primary aim of this systematic review is to critically appraise the reported method(s) of primary research studies that have used laser scanning IVCM to quantify corneal sub-basal nerve plexus (SBNP) parameters in humans, and to examine corneal nerve parameters in healthy individuals...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29099641/intraocular-lymphoma-masquerading-as-recurrent-iridocyclitis-findings-based-on-in-vivo-confocal-microscopy
#7
Pu Zhang, Jiao Tian, Ling Gao
PURPOSE: To emphasize the application prospects of in vivo confocal microscopy (IVCM) in distinguishing intraocular lesions from inflammatory and neoplastic diseases. METHODS: Retrospective case report. RESULTS: A patient with neoplastic masquerade syndrome initially underwent IVCM examination. After six separate intravitreal injections of 400 mg/0.1 ml methotrexate, IVCM revealed a complete remission of intraocular lymphoma. CONCLUSIONS: Although IVCM findings alone are not enough to diagnose intraocular neoplasm with absolute certainty, they can provide useful indication for distinguishing between intraocular inflammatory diseases and neoplasms...
November 3, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29077583/phenotypic-characterization-of-corneal-endothelial-dystrophy-in-german-shorthaired-and-wirehaired-pointers-using-in-vivo-advanced-corneal-imaging-and-histopathology
#8
Olivia R Shull, Christopher M Reilly, Lola B Davis, Christopher J Murphy, Sara M Thomasy
PURPOSE: To evaluate corneal morphology using ultrasonic pachymetry (USP), Fourier-domain optical coherence tomography (FD-OCT), and in vivo confocal microscopy (IVCM) in 2 related canine breeds-German shorthaired pointers (GSHPs) and German wirehaired pointers (GWHPs)-with and without corneal endothelial dystrophy (CED). This condition is characterized by premature endothelial cell degeneration leading to concomitant corneal edema and is similar to Fuchs endothelial corneal dystrophy...
October 25, 2017: Cornea
https://www.readbyqxmd.com/read/29053558/in-vivo-confocal-microscopy-reveals-corneal-reinnervation-after-treatment-of-neurotrophic-keratopathy-with-corneal-neurotization
#9
Simon S M Fung, Joseph Catapano, Uri Elbaz, Ronald M Zuker, Gregory H Borschel, Asim Ali
PURPOSE: To document the presence and location of new sensory nerve fibers after corneal neurotization using in vivo confocal microscopy (IVCM) in 2 patients with neurotrophic keratopathy (NK). METHODS: Two patients with unilateral advanced NK received corneal neurotization to surgically reinnervate the cornea. IVCM was used to identify subbasal nerve fibers and document corneal reinnervation. In 1 patient (case 1), IVCM was performed before and after corneal neurotization; in the second patient (case 2), IVCM was performed after neurotization and corneal transplantation...
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29032001/efficacy-of-self-retained-cryopreserved-amniotic-membrane-for-treatment-of-neuropathic-corneal-pain
#10
Melina I Morkin, Pedram Hamrah
PURPOSE: Treatment of neuropathic corneal pain (NCP) remains intricate, and involves a long-term combined multistep approach. The self-retained cryopreserved amniotic membrane (PROKERA(®), Bio-Tissue, Miami,FL) has been utilized for multiple ocular surface disorders. We evaluate the efficacy, safety, and tolerability of ProKera(®) Slim [PKS] and ProKera(®) Clear [PKC] in the treatment of NCP. METHODS: Retrospective case series of 9 patients who received PKS/PKC for the acute treatment of NCP...
October 12, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28990996/subbasal-nerve-plexus-changes-in-chronic-migraine
#11
Rohit Shetty, Rashmi Deshmukh, Rushad Shroff, Charmy Dedhiya, Chaitra Jayadev
PURPOSE: Migraine is a multifactorial disorder that presents with unilateral headache and several sensory symptoms. Photophobia is one of the ophthalmic manifestations that cause significant morbidity. The trigeminal pathway that innervates the cornea in the form of afferents has been implicated in photophobia associated with chronic migraine. This study investigates changes in the corneal subbasal nerve plexus (SBNP) in chronic migraine patients with and without photophobia. METHODS: Thirty-six patients with migraine and photophobia (group 1), 24 patients with migraine without photophobia (group 2), and 24 age- and sex-matched controls (group 3) were studied...
October 5, 2017: Cornea
https://www.readbyqxmd.com/read/28963702/in-vivo-confocal-laser-microscopy-of-morphologic-changes-after-small-incision-lenticule-extraction-with-accelerated-cross-linking-smile-xtra-in-patients-with-thin-corneas-and-high-myopia
#12
Yugui Zhou, Manli Liu, Ting Zhang, Hua Zheng, Yuan Sun, Xiaonan Yang, Shengbei Weng, Haiqin Lin, Quan Liu
PURPOSE: To evaluate the microstructural modifications and safety of small incision lenticule extraction combined with accelerated cross-linking (SMILE Xtra) in high myopia and thin corneas by means of in vivo confocal microscopy (IVCM) and 3D-OCT after a 6-month follow-up. METHODS: Forty-three eyes with high myopia and thin corneas were enrolled. All eyes underwent SMILE procedure. After the lenticule was extracted, 0.25% riboflavin was injected into the interface and allowed to diffuse for 60 s...
September 29, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28923503/in-vivo-confocal-microscopy-detects-bilateral-changes-of-corneal-immune-cells-and-nerves-in-unilateral-herpes-zoster-ophthalmicus
#13
Bernardo M Cavalcanti, Andrea Cruzat, Afsun Sahin, Deborah Pavan-Langston, Eric Samayoa, Pedram Hamrah
PURPOSE: To analyze bilateral corneal immune cell and nerve alterations in patients with unilateral herpes zoster ophthalmicus (HZO) by laser in vivo confocal microscopy (IVCM) and their correlation with corneal sensation and clinical findings. MATERIALS AND METHODS: This is a prospective, cross-sectional, controlled single-center study. Twenty-four eyes of 24 HZO patients and their contralateral clinically unaffected eyes and normal controls (n = 24) were included...
September 15, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28917411/accelerated-15%C3%A2-mw-pulsed-light-crosslinking-to-treat-progressive-keratoconus-two-year-clinical-results
#14
Cosimo Mazzotta, Stefano Baiocchi, Simone Alex Bagaglia, Mario Fruschelli, Alessandro Meduri, Miguel Rechichi
PURPOSE: To assess the clinical and microstructural results of accelerated 15 mW pulsed-light corneal crosslinking (CXL) to treat progressive keratoconus. SETTING: Siena Crosslinking Center, Siena, Italy. DESIGN: Prospective case series. METHODS: After epithelium removal (with Epi-Clear) and 10 minutes stromal soaking with riboflavin 0.1% hydroxypropyl methylcellulose solution, all eyes had 15 mW/cm(2) pulsed-light epithelium-off accelerated CXL for 6 minutes of ultraviolet-A (UVA) irradiation (1 second on/1 second off), maintaining a total UVA exposure of 12 minutes at a fluence of 5...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28894606/corneal-nerve-regeneration-after-self-retained-cryopreserved-amniotic-membrane-in-dry-eye-disease
#15
Thomas John, Sean Tighe, Hosam Sheha, Pedram Hamrah, Zeina M Salem, Anny M S Cheng, Ming X Wang, Nathan D Rock
PURPOSE: To evaluate the efficacy of self-retained cryopreserved amniotic membrane (CAM) in promoting corneal nerve regeneration and improving corneal sensitivity in dry eye disease (DED). METHODS: In this prospective randomized clinical trial, subjects with DED were randomized to receive CAM (study group) or conventional maximum treatment (control). Changes in signs and symptoms, corneal sensitivity, topography, and in vivo confocal microscopy (IVCM) were evaluated at baseline, 1 month, and 3 months...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28878217/in-vivo-confocal-microscopy-evaluation-of-ocular-surface-with-graft-versus-host-disease-related-dry-eye-disease
#16
Jingliang He, Yoko Ogawa, Shin Mukai, Yumiko Saijo-Ban, Mizuka Kamoi, Miki Uchino, Mio Yamane, Nobuhiro Ozawa, Masaki Fukui, Takehiko Mori, Shinichiro Okamoto, Kazuo Tsubota
Dry eye disease (DED) is often elicited by graft-versus-host disease (GVHD), an extensive complication of hematopoietic stem cell transplantation (HSCT). To unravel the mechanism of this type of DED, in vivo confocal microscopy (IVCM) was used to investigate alterations in the state of the sub-basal nerves, dendritic cells (DCs) and globular immune cells (GICs) in the central cornea and limbal epithelia. In this study, we examined 12 HSCT recipients with GVHD-caused DED and 10 HSCT recipients without GVHD-associated DED and evaluated the clinical parameters in the 2 groups...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28875340/corneal-features-in-ocular-graft-versus-host-disease-by-in-vivo-confocal-microscopy
#17
Tudor C Tepelus, Gloria B Chiu, Jyotsna Maram, Jianyan Huang, Vikas Chopra, SriniVas R Sadda, Olivia L Lee
PURPOSE: The purpose of our study was to determine the morphological features of the corneal epithelial layers, sub-basal nerve plexus and anterior stroma in patients with ocular graft-versus-host disease (oGVHD) compared to non-GVHD dry eyes and normal controls, using in vivo confocal microscopy (IVCM). METHODS: IVCM was used to capture central cornea images from eight volunteers with normal healthy eyes, ten patients with non-GVHD dry eye syndrome (DES) and 15 patients with clinically diagnosed oGVHD, in a cross-sectional study...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28852187/in-vivo-confocal-microscopy-of-posner-schlossman-syndrome-comparison-with-herpes-simplex-keratitis-hla-b27-anterior-uveitis-and-acute-attack-of-primary-angle-closure
#18
Ying Hong, Miao Wang, Lingling Wu
To investigate in vivo confocal microscopy (IVCM) findings in patients with Posner-Schlossman Syndrome (PSS), we compared the IVCM findings from the eyes of patients with: PSS (44 eyes); herpes simplex keratitis (HSK) (45 eyes); HLA-B27 anterior uveitis (B27AU) (45 eyes); and with acute attack of primary angle closure (aPAC) (43 eyes). The central Langerhans cells (LCs) grade at the level of corneal basal epithelial cells of the PSS group (2.33 ± 0.55) was similar to that of the HSK group (2.63 ± 0...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28768500/long-term-safety-and-tolerability-of-tafluprost-0-0015-vs-timolol-0-1-preservative-free-in-ocular-hypertensive-and-in-primary-open-angle-glaucoma-patients-a-cross-sectional-study
#19
Teresa Rolle, Roberta Spinetta, Raffaele Nuzzi
BACKGROUND: The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost 0.0015% versus preservative free (PF) Timolol 0.1% eyedrops in ocular hypertensive (OH) and in primary open-angle glaucoma (POAG) patients. METHODS: A cross-sectional study included patients in monotherapy for at least 36 months with Tafluprost 0...
August 3, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28751986/evaluation-of-bleb-morphology-and-reduction-in-iop-and-glaucoma-medication-following-implantation-of-a-novel-gel-stent
#20
Antonio Maria Fea, Roberta Spinetta, Paola Maria Loredana Cannizzo, Giulia Consolandi, Carlo Lavia, Vittoria Aragno, Francesco Germinetti, Teresa Rolle
OBJECTIVE: To evaluate the efficacy and safety of the Xen Gel Stent and provide a macro- and microscopic analyses of bleb morphology. METHODS: A prospective 12-month study on patients with primary open-angle glaucoma. Patients underwent implantation of the XEN Gel Stent (Allergan INC, Dublin, Ireland) either alone or combined with a cataract surgery. Biomicroscopy, in vivo confocal microscopy (IVCM), and anterior segment-optical coherence tomography (AS-OCT) were used to assess bleb morphology...
2017: Journal of Ophthalmology
keyword
keyword
77772
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"