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https://www.readbyqxmd.com/read/28801439/validation-of-asthma-recording-in-the-clinical-practice-research-datalink-cprd
#1
Francis Nissen, Daniel R Morales, Hana Mullerova, Liam Smeeth, Ian J Douglas, Jennifer K Quint
OBJECTIVES: The optimal method of identifying people with asthma from electronic health records in primary care is not known. The aim of this study is to determine the positive predictive value (PPV) of different algorithms using clinical codes and prescription data to identify people with asthma in the United Kingdom Clinical Practice Research Datalink (CPRD). METHODS: 684 participants registered with a general practitioner (GP) practice contributing to CPRD between 1 December 2013 and 30 November 2015 were selected according to one of eight predefined potential asthma identification algorithms...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800338/a-guideline-for-parkinson-s-disease-nurse-specialists-with-recommendations-for%C3%A2-clinical-practice
#2
Herma Lennaerts, Marieke Groot, Berna Rood, Koen Gilissen, Hella Tulp, Erik van Wensen, Marten Munneke, Teus van Laar, Bastiaan R Bloem
BACKGROUND: Parkinson's Disease Nurse Specialists (PDNS) play an important role in the care for patients with Parkinson's disease (PD) and their caregivers. Until now, there were no nursing guidelines in PD, and interventions were based solely on daily clinical practice because there is no evidence to support the merits of nursing interventions. Consequently, there is little uniformity in current care delivery. OBJECTIVE: Developing a guideline for PDNS. METHODS: We developed a guideline based on a questionnaire among PDNS and a literature review, supplemented with expert opinion plus the input of patients and caregivers...
August 11, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28792299/impact-of-medicaid-prescription-copayments-on-use-of-antipsychotics-and-other-medications-in-patients-with-schizophrenia
#3
Jalpa A Doshi, Pengxiang Li, Sunita Desai, Steven C Marcus
OBJECTIVE: To assess the impact of Medicaid prescription copayment policies on antipsychotic and other medication use among patients with schizophrenia. METHOD: The study sample included fee-for-service adult Medicaid patients with schizophrenia. Medicaid claims records from 2003-2005 from 42 states and D.C. were linked with county-level data from the Area Resource File and findings from a state Medicaid policy survey. Patient-level fixed-effects regression models examined the impact of increases in generic copayments and generic/brand copayment differentials on monthly use of antipsychotic (overall and by generic/brand status) and other non-antipsychotic medications...
August 9, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28792250/what-makes-medical-students-receptive-to-interprofessional-education-findings-from-an-exploratory-case-study
#4
Ahmed Osman
Interprofessional education (IPE) continues to grow as a field internationally, and therefore has become a key activity which numerous institutions have implemented around the world. A number of learner characteristics have been suggested as being important for the success of interprofessional interventions, including prior experiences, expectations, and motivations. This study sought to explore medical student engagement with IPE and the factors that affect this. Twelve final and penultimate year students took part in two focus groups to discuss previous IPE and the factors which they felt led to successful interprofessional experiences...
August 9, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28782212/knowledge-of-proprietary-and-generic-drug-names-among-hospital-prescribers-time-to-mandate-generic-prescribing
#5
Joshua S Davis, Thomas Barrett, Lisa Harris
Although medical students are taught clinical pharmacology using generic drug names, prescribing in hospitals often uses brand names. As a result, junior doctors may be prescribing drugs without knowing their nature or mode of action. We carried out a knowledge survey of 81 medical students and doctors at a 650-bed Australian teaching hospital to assess their knowledge of common drugs when given the brand name. We identified 20 commonly prescribed drugs and their brand names based on current hospital inpatients...
August 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28768476/pan-genome-and-phylogeny-of-bacillus-cereus-sensu-lato
#6
Adam L Bazinet
BACKGROUND: Bacillus cereus sensu lato (s. l.) is an ecologically diverse bacterial group of medical and agricultural significance. In this study, I use publicly available genomes and novel bioinformatic workflows to characterize the B. cereus s. l. pan-genome and perform the largest phylogenetic and population genetic analyses of this group to date in terms of the number of genes and taxa included. With these fundamental data in hand, I identify genes associated with particular phenotypic traits (i...
August 2, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28765130/the-child-s-perspective-on-discomfort-during-medical-research-procedures-a-descriptive-study
#7
Mira S Staphorst, Marc A Benninga, Margriet Bisschoff, Irma Bon, Jan J V Busschbach, Kay Diederen, Johannes B van Goudoever, Eric G Haarman, Joke A M Hunfeld, Vincent V W Jaddoe, Karin J M de Jong, Johan C de Jongste, Angelika Kindermann, Marsh Königs, Jaap Oosterlaan, Jan Passchier, Mariëlle W Pijnenburg, Liesbeth Reneman, Lissy de Ridder, Hyke G Tamminga, Henning W Tiemeier, Reinier Timman, Suzanne van de Vathorst
OBJECTIVE: The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a 'minimal discomfort' medical procedure. We exploratory study whether there are associations between age, anxiety-proneness, gender, medical condition, previous experiences and discomfort...
August 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28764724/pre-event-quality-of-life-and-its-influence-on-the-post-event-quality-of-life-among-patients-with-st-elevation-and-non-st-elevation-myocardial-infarctions-of-a-premier-province-of-sri-lanka
#8
P K B Mahesh, M W Gunathunga, Saroj Jayasinghe, S M Arnold, R Haniffa, A P De Silva
BACKGROUND: Pre-event Quality of Life (QOL) reflects the true social circumstances in which people live prior to the onset of myocardial infarctions. It is believed to be a predictor of the post-event QOL. The aim of this study was to describe the pre-event QOL and its influence on the post-event Quality of Life among patients with ST elevation (STEMI) and Non-ST elevation myocardial infarctions (NSTEMI) using Short Form-36 (SF-36), a generic QOL tool with 8 domains. Documented literature is rare in this regard in Sri Lanka, which is a lower-middle-income country...
August 1, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28763183/-the-most-cited-themes-in-the-research-in-the-field-of-mental-health-analyses-of-six-international-nursing-and-medical-journals
#9
Laura Cunico, Susanna Fredo, Massimo Bernini
INTRODUCTION: The review aimed to identify and analyse the future development on the topic by analysing the main themes discussed in number of scientific journal focused on Mental Health both by nurses and physicians.. METHOD: 4 international journals focused on Mental health and psychiatry International Journal of Mental Health Nursing, Archives of Psychiatric Nursing, American Journal of Psychiatry, Australian and New Zeland Journal of Psychiatry as well as two journal focused generically on health, Journal of Advanced Nursing and Lancet were scrutinized...
April 2017: Professioni Infermieristiche
https://www.readbyqxmd.com/read/28760344/-adapting-and-validating-the-generic-instrument-collaborate%C3%A2-to-measure-women-s-participation-in-health-related-decision-making-during-the-reproductive-process
#10
Paulina Bravo, Aixa Contreras, Angelina Dois, Luis Villarroel
INTRODUCTION: There is a worldwide interest in involving patients in health related decisions, so patients can actively search for therapeutic options and choose course of action that allows them to have better quality of life and wellbeing. The majority of the instruments available to capture the degree of participation in medical decision-making are in English and have been developed in high income countries. OBJECTIVE: To adapt and validate for the Chilean context the instrument CollaboRATE™, to measure women's participation in medical decisions during the reproductive process...
July 28, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28759866/oral-health-impacts-of-medications-used-to-treat-mental-illness
#11
N Cockburn, A Pradhan, M W Taing, S Kisely, P J Ford
BACKGROUND: Many psychotropic medications affect oral health. This review identified oral side effects for antidepressant, antipsychotic, anticonvulsant, antianxiety and sedative drugs that are recommended in Australia for the management of common mental illnesses and provides recommendations to manage these side-effects. METHODS: The Australian Therapeutic Guidelines and the Australian Medicines Handbook were searched for medications used to treat common mental health conditions...
July 23, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28756597/treatments-for-metastatic-prostate-cancer-mpc-a-review-of-costing-evidence
#12
REVIEW
Jan Norum, Carsten Nieder
BACKGROUND: Prostate cancer (PC) is the most common cancer in Western countries. More than one third of PC patients develop metastatic disease, and the 5-year expected survival in distant disease is about 35%. During the last few years, new treatments have been launched for metastatic castrate-resistant prostate cancer (mCRPC). OBJECTIVES: We aimed to review the current literature on health economic analysis on the treatment of metastatic prostate cancer (mPC), compare the studies, summarize the findings and make the results available to administrators and decision makers...
July 29, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28754425/thoroughness-of-community-pharmacists-assessment-and-communication-using-the-patient-care-process
#13
Mohammad B Nusair, Lisa M Guirguis
BACKGROUND: The patient care process (PCP) was adopted to move community pharmacy practice from the traditional dispensing role to a more professional level of patient care. However, research has not yet empirically characterized how pharmacists conduct the PCP in community pharmacies. OBJECTIVES: This study characterizes how pharmacists employ the PCP when evaluating medication appropriateness in a simulated community pharmacy setting. METHODS: A mixed methods analysis was employed to analyze simulated patient-pharmacist interactions (i...
July 15, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28753541/health-related-quality-of-life-among-children-with-turner-syndrome-controlled-cross-sectional-study
#14
Pascal Amedro, Nabil Tahhan, Helena Bertet, Claire Jeandel, Sophie Guillaumont, Thibault Mura, Marie-Christine Picot
BACKGROUND: The aim of the study was to assess health-related quality of life (HR-QoL) in children with Turner syndrome in comparison with controls. METHODS: We prospectively recruited 16 female girls with Turner syndrome (mean age 15.2±2.6 years) and 78 female controls (mean age 12.7±2.8 years) in randomly selected schools. We used the PedsQL, a generic HR-QoL questionnaire (self and parents' versions). RESULTS: Global HR-QoL scores in Turner syndrome were lower than controls for self-reports (respectively, 74...
August 28, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28753038/physician-experiences-with-high-value-care-in-internal-medicine-residency-mixed-methods-study-of-2003-2013-residency-graduates
#15
Kira L Ryskina, Eric S Holmboe, Judy A Shea, Esther Kim, Judith A Long
Phenomenon: High healthcare costs and relatively poor health outcomes in the United States have led to calls to improve the teaching of high value care (defined as care that balances potential benefits of interventions with their harms including costs) to physicians-in-training. Numerous interventions to increase high value care in graduate medical education were implemented at the national and local levels over the past decade. However, there has been little evaluation of their impact on physician experiences during training and perceived preparedness for practice...
July 28, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28738838/improved-detection-of-genus-specific-alphavirus-using-a-generic-taqman%C3%A2-assay
#16
Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque, Marie-Christine Jaffar-Bandjee
BACKGROUND: Alphaviruses are arthropod borne RNA viruses of medical importance. Geographical expansion of mosquitoes of the Aedes genus in the past decades has been associated with major Alphavirus-associated outbreaks. Climate changes and intensification of air travels have favored vector expansion and virus dissemination in new territories leading to virus emergence not only in tropical areas but also in temperate regions. The detection of emergence is based upon surveillance networks with epidemiological and laboratory investigation...
July 24, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28736014/efficacy-and-safety-of-generic-mycophenolate-mofetil-my-rept-500-milligram-tablets-in-primary-liver-transplant-recipients
#17
S K Hong, K-W Lee, K C Yoon, H-S Kim, H Kim, N-J Yi, K-S Suh
BACKGROUND: Generic immunosuppressants may be cost-effective if clinical outcomes are equivalent to the brand-name medications. Mycophenolate mofetil in the form of My-rept may be cost-effective being a generic immunosuppressant, which is available as a 500-mg tablet as well as a 250-mg capsule (Chong Kun Dang Pharmaceutical Corporation, Seoul, Korea). OBJECTIVE: This study aimed to evaluate the efficacy, safety, cost-effectiveness, and convenience of My-rept 500-mg tablets in liver transplant recipients...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28733752/generic-immunosuppressants
#18
Mara Medeiros, Julia Lumini, Noah Stern, Gilberto Castañeda-Hernández, Guido Filler
Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient. However, serious adverse events caused by the transition from innovator to generic medications, specifically in pediatric solid organ transplant recipients, have questioned these autosubstitutions. The purpose of this review is to summarize the criteria set forth by the regulatory bodies, and to examine how major immunosuppressive drugs conform to these recommendations...
July 21, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28732621/generic-trypan-blue-as-possible-cause-of%C3%A2-a%C3%A2-cluster-of-toxic-anterior-segment-syndrome-cases-after-uneventful-cataract%C3%A2-surgery
#19
Artemis Matsou, Argyrios Tzamalis, Nikolaos Chalvatzis, Asimina Mataftsi, Ioannis Tsinopoulos, Periklis Brazitikos
Five of 16 patients having uneventful cataract surgery over 2 consecutive days presented on the first postoperative day with painless, unexpected blurry vision; marked limbus-to-limbus corneal edema; and severe anterior chamber inflammation with hypopyon and fibrin formation. Review of the records showed the 5 patients had received an intracameral injection of generic trypan blue solution 0.06% to facilitate the capsulorhexis. Patients who had not received the trypan blue injection had an uneventful first-day check and subsequent course...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28728507/disease-specific-quality-of-life-in-patients-with-lupus-nephritis
#20
M Jolly, S Toloza, B Goker, A E Clarke, S V Navarra, D Wallace, M Weisman, C C Mok
Background Patient-reported outcomes in lupus nephritis (LN) are not well studied. Studies with disease-targeted PRO tool in LN do not exist. Herein, we describe quality of life (QOL: HRQOL & non-HRQOL) among LN patients using LupusPRO. Methods International, cross-sectional data from 1259 patients with systemic lupus erythematosus (SLE) and LupusPRO were compared, stratified by (a) presence of LN (ACR classification criteria (ACR-LN)) at any time and, (b) active LN (on SLEDAI) at study visit. Damage was assessed by SLICC/ACR-SDI...
January 1, 2017: Lupus
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