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https://www.readbyqxmd.com/read/28343650/-surveillance-system-on-drug-abuse-interest-of-the-french-national-oppidum-program-of-french-addictovigilance-network
#1
Elisabeth Frauger, Liselotte Pochard, Quentin Boucherie, Adeline Giocanti, Cécile Chevallier, Amélie Daveluy, Valérie Gibaja, Anne-Sylvie Caous, Céline Eiden, Nicolas Authier, Reynald Le Boisselier, Marylène Guerlais, Émilie Jouanjus, Marion Lepelley, Véronique Pizzoglio, Stéphanie Pain, Nathalie Richard, Joëlle Micallef
It is important to assess drug abuse liability in 'real life' using different surveillance systems. OPPIDUM ('Observation of illegal drugs and misuse of psychotropic medications') surveillance system anonymously collects information on drug abuse and dependence observed in patients recruited in specialized care centers dedicated to drug dependence. The aim of this article is to demonstrate the utility of OPPIDUM system using 2015 data. OPPIDUM is a cross-sectional survey repeated each year since 1995. In 2015, 5003 patients described the modality of use of 10,159 psychoactive drugs...
February 22, 2017: Thérapie
https://www.readbyqxmd.com/read/28336760/analysis-of-variations-in-the-display-of-drug-names-in-computerized-prescriber-order-entry-systems
#2
Arbor J L Quist, Thu-Trang T Hickman, Mary G Amato, Lynn A Volk, Alejandra Salazar, Alexandra Robertson, Adam Wright, David W Bates, Shobha Phansalkar, Bruce L Lambert, Gordon D Schiff
PURPOSE: The variations in how drug names are displayed in computerized prescriber-order-entry (CPOE) systems were analyzed to determine their contribution to potential medication errors. METHODS: A diverse set of 10 inpatient and outpatient CPOE system vendors and self-developed CPOE systems in 6 U.S. healthcare institutions was evaluated. A team of pharmacists, physicians, patient-safety experts, and informatics experts created a CPOE assessment tool to standardize the assessment of CPOE features across the systems studied...
April 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28331330/work-family-conflict-as-a-mediator-between-occupational-stress-and-psychological-health-among-mental-health-nurses-in-japan
#3
Norio Sugawara, Kazuma Danjo, Hanako Furukori, Yasushi Sato, Tetsu Tomita, Akira Fujii, Taku Nakagami, Kazuyo Kitaoka, Norio Yasui-Furukori
BACKGROUND: Occupational stress among mental health nurses may affect their psychological health, resulting in reduced performance. To provide high-quality, sustainable nursing care, it is necessary to identify and control the factors associated with psychological health among mental health nurses. The purpose of this study was to examine the role of work-family conflict (WFC) in the well-known relationship between occupational stress and psychological health among mental health nurses in Japan...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28323753/budget-impact-of-antiretroviral-therapy-in-a-french-clinic-cohort-anrs-gota
#4
Emmanuelle Papot, Roland Landman, Françoise Louni, Charlotte Charpentier, Gilles Peytavin, Agnès Certain, Clémence Fradet, Daniela Rojas Castro, Marie Preau, Cécile Goujard, Patrick Yeni, Yazdan Yazdanpanah
OBJECTIVES: In this study, we first assessed costs associated with the use of ART in an infectious diseases University Hospital Clinic, we secondly evaluated characteristics associated with these costs, and finally simulated the impact on the overall ART budget of switching 1- and 2-line regimens to less costly regimens (as effective and well-tolerated). DESIGN: Cohort analysis including PLHIV ≥ 18 years on ART to estimate ART costs during 2014. METHODS: This study was conducted in the Bichat-Claude Bernard University Hospital Clinic in Paris, France, where 4,501 PLHIV consulted in 2014...
March 18, 2017: AIDS
https://www.readbyqxmd.com/read/28321264/fast-parabola-detection-using-estimation-of-distribution-algorithms
#5
Jose de Jesus Guerrero-Turrubiates, Ivan Cruz-Aceves, Sergio Ledesma, Juan Manuel Sierra-Hernandez, Jonas Velasco, Juan Gabriel Avina-Cervantes, Maria Susana Avila-Garcia, Horacio Rostro-Gonzalez, Roberto Rojas-Laguna
This paper presents a new method based on Estimation of Distribution Algorithms (EDAs) to detect parabolic shapes in synthetic and medical images. The method computes a virtual parabola using three random boundary pixels to calculate the constant values of the generic parabola equation. The resulting parabola is evaluated by matching it with the parabolic shape in the input image by using the Hadamard product as fitness function. This proposed method is evaluated in terms of computational time and compared with two implementations of the generalized Hough transform and RANSAC method for parabola detection...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28321111/relationships-between-clinical-self-reported-and-donation-specific-outcomes-a-prospective-follow-up-study-10-years-after-kidney-donation
#6
Käthe B Meyer, Anders Hartmann, Geir Mjøen, Marit H Andersen
BACKGROUND Long-term consequences of donor nephrectomy might be reduced kidney function, increased risk for cardiovascular disease, impaired quality of life, and fatigue. Few studies have investigated associations between clinical and self-reported outcomes in a long-term perspective. Thus, we aimed to investigate relationships between clinical, self-reported, and donation-specific outcomes in a nationwide cohort. MATERIAL AND METHODS We conducted a prospective follow-up study and assessed pre- and post-donation data from 202 donors who donated in 2001-2004...
March 21, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28297991/solvent-free-molecular-level-modeling-of-self-assembling-amphiphiles-in-water
#7
Somajit Dey, Jayashree Saha
Aggregation mesophases of self-assembling amphiphiles in water are highly important in the context of biology (biomembranes), therapy (liposomes), industry (polymer surfactants), and condensed-matter physics (lyotropic liquid crystals). Besides helping to increase fundamental understanding of collective molecular behavior, simulations of these lyotropic phases are pivotal to technological and medical developments such as smart drug carriers for gene therapy. Implicit-solvent, coarse-grained, low resolution modeling with a simple pair potential is the key to realizing the larger length and time scales associated with such mesoscopic phenomena during a computer simulation...
February 2017: Physical Review. E
https://www.readbyqxmd.com/read/28294925/-assessing-the-quality-of-the-medical-learning-environment-comparison-of-two-validated-dutch-questionnaires
#8
P L P Brand, A D C Jaarsma, J Schönrock-Adema
- Assessing the quality of the medical learning environment is an important part of the quality cycle of postgraduate medical education programmes.- The quality of the medical learning environment is primarily assessed by systematically documenting the experiences of doctors-in-training (residents).- For this purpose, several questionnaires have been developed, two of which have been specifically developed for use in the Dutch clinical learning environment.- D-RECT is a commonly-used, 50-item questionnaire (11 subscales), developed from qualitative research on the optimal learning environment for ObGyn residents...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28290847/-comparative-analysis-of-the-efficacy-and-safety-of-rosuvastatin-and-original-rosuvastatin
#9
B Ya Bart, E E Luchinkina, I G Gordeev, G P Arutyunov, E O Taratukhin On Behalf Of The Workgroup Of Paritet Trial
The study is one of the priority points of the Russian Scientific Medical Society of Internal Medicine, initiated due to known high average level of LDL cholesterol in Russian population and necessity for its optimized control by better access to treatment. AIM: To conduct comparative analysis of efficacy and safety of the rosuvastatin compound akorta and original rosuvastatin crestor. MATERIAL AND METHODS: To randomized crossover study (PARITET) 60 patients were included with the diagnosis dyslipidemia...
June 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290736/accuracy-and-reliability-of-marker-based-approaches-to-scale-the-pelvis-thigh-and-shank-segments-in-musculoskeletal-models
#10
Hans Kainz, Hoa Hoang, Chris Stockton, Roslyn R Boyd, David G Lloyd, Christopher P Carty
Gait analysis together with musculoskeletal modelling is widely used for research. In the absence of medical images, surface marker locations are used to scale a generic model to the individual's anthropometry. Studies evaluating the accuracy and reliability of different scaling approaches in a paediatric and/or clinical population have not yet been conducted and, therefore, formed the aim of this study. Magnetic resonance images (MRI) and motion capture data were collected from twelve participants with cerebral palsy and six typically developed participants...
March 14, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28288619/medication-related-calls-received-by-a-national-telenursing-triage-and-advice-service-in-australia-a-retrospective-cohort-study
#11
Ling Li, Rebecca Lake, Magdalena Z Raban, Mary Byrne, Maureen Robinson, Johanna Westbrook, Melissa T Baysari
BACKGROUND: Telenursing triage and advice services are increasingly being used to deliver health advice. Medication-related queries are common, however little research has explored the medication-related calls made to these services. The aim of this study was to examine the profile of medication-related calls to a national telenursing triage and advice service and the medications involved. METHODS: This was a retrospective cohort study of medication-related calls received by Australia's national helpline (healthdirect helpline) in 2014, which provides free advice from registered nurses...
March 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28286600/doctor-ai-predicting-clinical-events-via-recurrent-neural-networks
#12
Edward Choi, Mohammad Taha Bahadori, Andy Schuetz, Walter F Stewart, Jimeng Sun
Leveraging large historical data in electronic health record (EHR), we developed Doctor AI, a generic predictive model that covers observed medical conditions and medication uses. Doctor AI is a temporal model using recurrent neural networks (RNN) and was developed and applied to longitudinal time stamped EHR data from 260K patients over 8 years. Encounter records (e.g. diagnosis codes, medication codes or procedure codes) were input to RNN to predict (all) the diagnosis and medication categories for a subsequent visit...
August 2016: JMLR Workshop and Conference Proceedings
https://www.readbyqxmd.com/read/28285775/the-certainty-in-consumers-willingness-to-accept-pharmacist-provided-medication-therapy-management-services
#13
Lawrence M Brown, Mohamed E Rashrash, Jon C Schommer
OBJECTIVES: To describe consumers' willingness to accept medication therapy management (MTM) services provided by a pharmacist. DESIGN: Cross-sectional Internet survey included questions about willingness to use 11 components of MTM services. PARTICIPANTS: The data of 8352 United States' adults who were on 3 or more medications were obtained from the 2015 National Consumer Survey on the Medication Experience and Pharmacists' Roles, which included 26,173 respondents...
March 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28276076/managing-the-oral-side-effects-of-medications-used-to-treat-multiple-sclerosis
#14
N Cockburn, K Pateman, M W Taing, A Pradhan, P J Ford
BACKGROUND: Many medications used to manage multiple sclerosis (MS) affect oral health. This review aimed to identify the oral side effects of the current drugs recommended in Australia to treat MS and make dental practitioners aware of the range of symptoms. METHODS: The Australian Therapeutic Guidelines and the Australian Medicines Handbook were searched for medications used to treat MS. For each medication, the generic name, class, route of administration, dosage and drug company reported side-effects were extracted from the online Monthly Index of Medical Specialties (MIMs) database...
March 9, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28275425/a-clinical-and-ethical-review-on-late-results-and-benefits-after-evar
#15
REVIEW
Carlo Setacci, Pasqualino Sirignano, Vittorio Fineschi, Paola Frati, Giovanna Ricci, Francesco Speziale
INTRODUCTION: The aim of this review is to assess if late mortality after endovascular repair (EVAR) of abdominal aortic aneurysms (AAA) is a real problem, and whether it could be an issue in the case of medical litigation. MATERIAL AND METHODS: A review of all English language literature was performed on PubMed web-site, looking for all papers reporting EVAR long-term mortality rate. EVAR performances were reviewed also from an ethical and medico-legal point of view, based on current Italian laws...
April 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28270711/provider-decisions-and-patient-outcomes-after-premature-metformin-discontinuation
#16
Jessica N Bradley, Krystal L Edwards, Jennifer T Gunter, Rick A Weideman, Kevin C Kelly
The purpose of this study was to evaluate the effects of alternative antihyperglycemic therapy after discontinuation of metformin due to documented declining renal function. This retrospective, single-site study evaluated patients who had metformin discontinued between 1 January 1999 and 30 September 2013. Medical records were evaluated for documented adverse events, subsequent glycemic control, and costs associated with the alternative therapy. Patients served as their own controls. A total of 179 patients met study entry criteria, and their peak A1C was significantly higher within the year after metformin discontinuation (P <0...
February 2017: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/28270383/patterns-and-predictors-of-adherence-to-statin-therapy-among-older-patients-protocol-for-a-systematic-review
#17
Richard Ofori-Asenso, Ella Zomer, Andrea Curtis, Andrew Tonkin, Mark Nelson, Manoj Gambhir, Danny Liew, Sophia Zoungas
BACKGROUND: The benefits of statin therapy are significantly compromised by noncompliance. Although elderly patients may have particular challenges with medication adherence and persistence, previous reviews on statin adherence have not focused on this population. Additionally, comparisons of adherence and persistence specific to statin indication (primary or secondary prevention) have not been thoroughly explored. OBJECTIVE: We aim to assess the extent of, and factors associated with, adherence and persistence to statin therapy among older populations (aged ≥65 years)...
March 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28269080/convolutive-blind-source-separation-on-surface-emg-signals-for-respiratory-diagnostics-and-medical-ventilation-control
#18
Herbert Buchner, Eike Petersen, Marcus Eger, Philipp Rostalski
The electromyogram (EMG) is an important tool for assessing the activity of a muscle and thus also a valuable measure for the diagnosis and control of respiratory support. In this article we propose convolutive blind source separation (BSS) as an effective tool to pre-process surface electromyogram (sEMG) data of the human respiratory muscles. Specifically, the problem of discriminating between inspiratory, expiratory and cardiac muscle activity is addressed, which currently poses a major obstacle for the clinical use of sEMG for adaptive ventilation control...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267912/a-proposal-for-the-study-of-cementless-short-stem-hip-prostheses
#19
REVIEW
F Gómez-García, M Fernández-Fairen, R L Espinosa-Mendoza
BACKGROUND: With the recent evolution of hip arthroplasty, new models of short stems have emerged. So far, we do not have a clear strategy to analyze their outcomes, since there is confusion around the definition of short stem and there is no consensus for their classification. PURPOSES: The purpose of this study was to review the current state of the art of cementless short stems considering the main design characteristics; it provides a definition of short stem and proposes a classification, grouping them into families by means of a nomenclature that describes them accurately...
July 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28265974/elder-abuse-in-europe-s-most-elderly-city-an-assessment-of-the-phenomenon-and-an-analysis-of-the-data-from-the-penal-court-of-genoa-from-2010-to-2015
#20
Andrea Molinelli, Francesco Ventura, Sara Lo Pinto, Martina Drommi, Francesco De Stefano
INTRODUCTION: In Italy, 5% of the elderly are estimated to have suffered abuse. While the Penal Code refers to generic types of abuse, such as physical and psychological maltreatment, abandonment and financial fraud, it does not specifically protect the elderly as a category. AIMS: To assess the frequency and modalities of elder abuse in Genoa and its Province, and to compare these data with those reported in the literature, in order to provide a picture of the current situation that can be used by the authorities to combat this phenomenon...
March 6, 2017: Aging Clinical and Experimental Research
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