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https://www.readbyqxmd.com/read/28091389/trali-syndrome-during-the-treatment-of-a-plasmodium-falciparum-malaria-case
#1
Hülya Çaşkurlu, Rahman Nurmuhammedov, Zarni Htway
Malaria, which is one of the three most important infectious diseases globally, is endemic in many areas of the world. Plasmodium falciparum is not endemic to Turkey but can be seen after travel to epidemic countries. Transfusion-related acute lung injury (TRALI) syndrome is a rare disease, which may develop following the transfusion of all types of blood products, including plasma. Here we describe a case of TRALI syndrome in a 29-year-old male, who presented with fever after 15 days of returning from a business trip to Burkina Faso...
December 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28086864/direct-detection-of-falciparum-and-non-falciparum-malaria-dna-from-a-drop-of-blood-with-high-sensitivity-by-the-dried-lamp-system
#2
Kyoko Hayashida, Kiichi Kajino, Humphrey Simukoko, Martin Simuunza, Joseph Ndebe, Amos Chota, Boniface Namangala, Chihiro Sugimoto
BACKGROUND: Because of the low sensitivity of conventional rapid diagnostic tests (RDTs) for malaria infections, the actual prevalence of the diseases, especially those caused by non-Plasmodium falciparum (non-Pf) species, in asymptomatic populations remain less defined in countries lacking in well-equipped facilities for accurate diagnoses. Our direct blood dry LAMP system (CZC-LAMP) was applied to the diagnosis of malaria as simple, rapid and highly sensitive method as an alternative for conventional RDTs in malaria endemic areas where laboratory resources are limited...
January 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28086789/detection-of-plasmodium-knowlesi-plasmodium-falciparum-and-plasmodium-vivax-using-loop-mediated-isothermal-amplification-lamp-in-a-co-endemic-area-in-malaysia
#3
Kim A Piera, Ammar Aziz, Timothy William, David Bell, Iveth J González, Bridget E Barber, Nicholas M Anstey, Matthew J Grigg
BACKGROUND: Plasmodium knowlesi is the most common cause of malaria in Malaysia. However, microscopic diagnosis is inaccurate and rapid diagnostic tests (RDTs) are insufficiently sensitive. PCR is sensitive and specific but not feasible at a district level. Loop-mediated isothermal amplification (LAMP) shows potential with only basic requirements. A commercially available LAMP assay, the Eiken Loopamp™ MALARIA Pan Detection kit, is sensitive for Plasmodium falciparum and Plasmodium vivax, but has not previously been evaluated for P...
January 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28077745/congenital-plasmodium-falciparum-malaria-in-washington-dc
#4
Melissa Del Castillo, Ann Marie Szymanski, Ariella Slovin, Edward C C Wong, Roberta L DeBiasi
Congenital malaria is rare in the United States, but is an important diagnosis to consider when evaluating febrile infants. Herein, we describe a case of congenital Plasmodium falciparum malaria in a 2-week-old infant born in the United States to a mother who had emigrated from Nigeria 3 months before delivery.
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28061871/lamp-kit-for-diagnosis-of-non-falciparum-malaria-in-plasmodium-ovale-infected-patients
#5
Juan Cuadros, Alexandra Martin Ramírez, Iveth J González, Xavier C Ding, Ramon Perez Tanoira, Gerardo Rojo-Marcos, Peña Gómez-Herruz, Jose Miguel Rubio
BACKGROUND: Microscopy and rapid diagnosis tests have a limited sensitivity in diagnosis of malaria by Plasmodium ovale. The LAMP kit (LoopAMP®) can be used in the field without special equipment and could have an important role in malaria control programmes in endemic areas and for malaria diagnosis in returned travellers. The performance of the Pan primer of the kit in detecting malaria by P. ovale was compared with the results of standard nPCR in samples of patients returning from P...
January 7, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28056949/the-treatment-of-non-malarial-febrile-illness-in-papua-new-guinea-findings-from-cross-sectional-and-longitudinal-studies-of-health-worker-practice
#6
Olga P M Saweri, Manuel W Hetzel, Ivo Mueller, Peter M Siba, Justin Pulford
BACKGROUND: The Papua New Guinea Department of Health recently shifted from a presumptive to a 'test and treat' malaria case management policy. This shift was supported by the widespread introduction of malaria rapid diagnostic tests in health facilities across the country. Health workers received training and job-aids detailing how to conduct and interpret a malaria rapid diagnostic test and how to treat test positive cases; however, little instruction on treating non-malaria febrile cases was provided...
January 5, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28051216/malaria-outside-a-living-in-endemic-areas-diagnosis-and-measures-to-take
#7
Emna Siala, Dhikrayet Gamara, Karim Aoun, Aida Bouratbine
In spite of its elimination from Tunisia, malaria remains a public health concern due to the severity of the disease and risk of its reintroduction. The vulnerability of our country is related to the persistent anophelism and to the existence of a potential reservoir represented by imported cases. In the absence of a stay in an endemic area, the suspicion of malaria remains a rare event. However, in front of the possibility of other modes of contamination, this parasitosis must be evoked in any fever without obvious etiology...
June 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28049536/usefulness-of-a-biomarker-to-identify-placental-dysfunction-in-the-context-of-malaria
#8
REVIEW
Alexandra Gueneuc, Philippe Deloron, Gwladys I Bertin
In most tropical areas, pregnant women are at increased risk of malaria, as a consequence of the massive sequestration of parasitized red blood cells in the placenta. The placenta plays a key role in embryonic and fetal development as well as in maternal-fetal exchanges, and pregnancy-associated malaria may alter selected placenta functions that lead to stillbirth and low birth weight. Although there are several tools (blood smear examination, RDT, PCR) to diagnose malaria infection during pregnancy, there is currently no test to assess placenta dysfunction in the framework of pregnancy-associated malaria...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28049489/evidence-of-non-plasmodium-falciparum-malaria-infection-in-k%C3%A3-dougou-s%C3%A3-n%C3%A3-gal
#9
Rachel F Daniels, Awa Bineta Deme, Jules F Gomis, Baba Dieye, Katelyn Durfee, Julie I Thwing, Fatou B Fall, Mady Ba, Medoune Ndiop, Aida S Badiane, Yaye Die Ndiaye, Dyann F Wirth, Sarah K Volkman, Daouda Ndiaye
BACKGROUND: Expanded malaria control efforts in Sénégal have resulted in increased use of rapid diagnostic tests (RDT) to identify the primary disease-causing Plasmodium species, Plasmodium falciparum. However, the type of RDT utilized in Sénégal does not detect other malaria-causing species such as Plasmodium ovale spp., Plasmodium malariae, or Plasmodium vivax. Consequently, there is a lack of information about the frequency and types of malaria infections occurring in Sénégal...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28049485/the-dangers-of-accepting-a-single-diagnosis-case-report-of-concurrent-plasmodium-knowlesi-malaria-and-dengue-infection
#10
Soon Eu Chong, Rhendra Hardy Mohamad Zaini, Siti Suraiya, Kok Tong Lee, Jo Anne Lim
BACKGROUND: Dengue and malaria are two common, mosquito-borne infections, which may lead to mortality if not managed properly. Concurrent infections of dengue and malaria are rare due to the different habitats of its vectors and activities of different carrier mosquitoes. The first case reported was in 2005. Since then, several concurrent infections have been reported between the dengue virus (DENV) and the malaria protozoans, Plasmodium falciparum and Plasmodium vivax. Symptoms of each infection may be masked by a simultaneous second infection, resulting in late treatment and severe complications...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28049481/expanding-access-to-parasite-based-malaria-diagnosis-through-retail-drug-shops-in-tanzania-evidence-from-a-randomized-trial-and-implications-for-treatment
#11
Kathleen Maloney, Abigail Ward, Bonnie Krenz, Nora Petty, Lindsay Bryson, Caitlin Dolkart, Theodoor Visser, Arnaud Le Menach, Valerie K Scott, Justin M Cohen, Esther Mtumbuka, Sigsbert Mkude
BACKGROUND: Tanzania has seen a reduction in the fraction of fevers caused by malaria, likely due in part to scale-up of control measures. While national guidelines require parasite-based diagnosis prior to treatment, it is estimated that more than half of suspected malaria treatment-seeking in Tanzania initiates in the private retail sector, where diagnosis by malaria rapid diagnostic test (RDT) or microscopy is illegal. This pilot study investigated whether the introduction of RDTs into Accredited Drug Dispensing Outlets (ADDOs) under realistic market conditions would improve case management practices...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28036313/pretreatment-elevated-erythrocyte-sedimentation-rate-and-c-reactive-protein-as-a-predictor-of-malarial-complications
#12
Sachin Vemula, Vidyalakshmi Katara, Unnikrishnan Bhaskaran, Sushma Adappa, Mahabala Chakrapani
INTRODUCTION: Complications of malaria can develop suddenly and unexpectedly. Although various parameters have been associated with severity of malaria, they have not been studied as predictors of these events. Many of the malarial complications are inflammatory in nature, and C-reactive protein (CRP) and elevated erythrocyte sedimentation rate (ESR) could be early markers of these complications and might precede and predict the development of complications. METHODOLOGY: A total of 122 inpatients with uncomplicated newly diagnosed malaria were studied...
December 30, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28035638/-evaluation-of-malaria-rapid-diagnostic-test-optimal-it%C3%A2-pldh-along-the-plasmodium-falciparum-distribution-limit-in-mauritania
#13
H Ba, A D Ahouidi, C W Duffy, Y B Deh, C Diedhiou, A Tandia, M Y Diallo, S Assefa, B B Lô, M B Elkory, D J Conway
Performance of the malaria Rapid Diagnostic Test (RDT) OptiMal-IT® was evaluated in Mauritania where malaria is low and dependent on a short transmission season. Slide microscopy was considered as the reference method of diagnosis. Febrile patients with suspected malaria were recruited from six health facilities, 3 urban and 3 rural, during two periods (December 2011 to February 2012, and August 2012 to March 2013). Overall, 780 patients were sampled, with RDT and thick blood film microscopy results being obtained for 759 of them...
December 29, 2016: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28034892/how-i-treat-anemia-in-pregnancy-iron-cobalamin-and-folate
#14
Maureen M Achebe, Anat Gafter-Gvili
Anemia of pregnancy is considered a global health problem, affecting almost 50% of pregnant women. Anemia is an important risk factor for both fetal and maternal morbidity. The purpose of this article is to discuss diagnosis and management of the most frequent causes of anemia in pregnancy: iron, cobalamin and folate deficiencies. This paper considers three clinical cases. Iron deficiency is the most common cause. The laboratory tests that define iron deficiency, the recognition of developmental delays and cognitive abnormalities in iron-deficient neonates and the literature addressing the efficacy and safety of intravenous iron in pregnancy are reviewed...
December 29, 2016: Blood
https://www.readbyqxmd.com/read/28025283/costs-and-cost-effectiveness-of-plasmodium-vivax-control
#15
Michael T White, Shunmay Yeung, Edith Patouillard, Richard Cibulskis
The continued success of efforts to reduce the global malaria burden will require sustained funding for interventions specifically targeting Plasmodium vivax The optimal use of limited financial resources necessitates cost and cost-effectiveness analyses of strategies for diagnosing and treating P. vivax and vector control tools. Herein, we review the existing published evidence on the costs and cost-effectiveness of interventions for controlling P. vivax, identifying nine studies focused on diagnosis and treatment and seven studies focused on vector control...
December 28, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28000753/plasmodium-falciparum-malaria-importation-from-africa-to-china-and-its-mortality-an-analysis-of-driving-factors
#16
Shengjie Lai, Nicola A Wardrop, Zhuojie Huang, Claudio Bosco, Junling Sun, Tomas Bird, Amy Wesolowski, Sheng Zhou, Qian Zhang, Canjun Zheng, Zhongjie Li, Andrew J Tatem, Hongjie Yu
Plasmodium falciparum malaria importation from Africa to China is rising with increasing Chinese overseas investment and international travel. Identifying networks and drivers of this phenomenon as well as the contributors to high case-fatality rate is a growing public health concern to enable efficient response. From 2011-2015, 8653 P. falciparum cases leading to 98 deaths (11.3 per 1000 cases) were imported from 41 sub-Saharan countries into China, with most cases (91.3%) occurring in labour-related Chinese travellers...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27989276/-beyond-test-and-treat-malaria-diagnosis-for-improved-pediatric-fever-management-in-sub-saharan-africa-by-emily-white-johansson
#17
S Patrick Kachur
No abstract text is available yet for this article.
2016: Global Health Action
https://www.readbyqxmd.com/read/27989273/beyond-test-and-treat-malaria-diagnosis-for-improved-pediatric-fever-management-in-sub-saharan-africa
#18
Emily White Johansson
BACKGROUND: Malaria rapid diagnostic tests (RDTs) have great potential to improve quality care and rational drug use in malaria-endemic settings although studies have shown common RDT non-compliance. Yet, evidence has largely been derived from limited hospital settings in few countries. This article reviews a PhD thesis that analyzed national surveys from multiple sub-Saharan African countries to generate large-scale evidence of malaria diagnosis practices and its determinants across different contexts...
2016: Global Health Action
https://www.readbyqxmd.com/read/27986419/epilepsy-in-the-tropics-emerging-etiologies
#19
Jaime Carrizosa Moog, Angelina Kakooza-Mwesige, Chong Tin Tan
Epilepsy is considered by the World Health Organization a public health priority with more than 50 million human beings affected by the disease. More than 80% of persons with epilepsy live in low and middle income countries and most of them in tropical areas. Several emerging, re-emerging and neglected diseases are symptomatic etiologies that jointly contribute to the enormous global burden of epilepsy. Besides the clinical strengths to reduce diagnostic and treatment gaps, other strategies in social, economic, cultural, educational and health policies are needed to prevent and treat appropriately vulnerable and affected persons with epilepsy...
December 6, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27980857/comparative-antibody-responses-against-three-antimalarial-vaccine-candidate-antigens-from-urban-and-rural-exposed-individuals-in-gabon
#20
Roméo-Karl Imboumy-Limoukou, Sandrine Lydie Oyegue-Liabagui, Stella Ndidi, Irène Pegha-Moukandja, Charlene Lady Kouna, Francis Galaway, Isabelle Florent, Jean Bernard Lekana-Douki
The analysis of immune responses in diverse malaria endemic regions provides more information to understand the host's immune response to Plasmodium falciparum. Several plasmodial antigens have been reported as targets of human immunity. PfAMA1 is one of most studied vaccine candidates; PfRH5 and Pf113 are new promising vaccine candidates. The aim of this study was to evaluate humoral response against these three antigens among children of Lastourville (rural area) and Franceville (urban area). Malaria was diagnosed using rapid diagnosis tests...
December 1, 2016: European Journal of Microbiology & Immunology
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