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https://www.readbyqxmd.com/read/28931989/effect-of-low-intensity-pulsed-ultrasound-therapy-on-a-rat-knee-joint-contracture-model
#1
Masanori Watanabe, Satoshi Kojima, Masahiro Hoso
[Purpose] Histopathological investigation of the effects of low-intensity pulsed ultrasound (LIPUS) on joint components using a rat knee joint contracture model. [Subjects and Methods] Nineteen, 9-week-old Wistar male rats were divided into a control group (n=6) and an experimental group. Rats in the experimental group underwent cast immobilization of the right rear limb for 8 weeks. They were then randomly divided into a non-treatment group (n=6), which was raised under normal conditions for 4 weeks, and a treatment group (n=7), which underwent LIPUS for 4 weeks...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28929363/all-in-one-low-intensity-pulsed-ultrasound-stimulation-system-using-piezoelectric-micromachined-ultrasonic-transducer-pmut-arrays-for-targeted-cell-stimulation
#2
Wonjun Lee, Seungjun Yoo, Joontaek Jung, Woojin Kang, Wei Wang, Cheil Moon, Hongsoo Choi
A novel cell-stimulation system was fabricated using 10 × 29 piezoelectric micromachined ultrasonic transducer (pMUT) arrays for targeted ultrasonic cell stimulation. Both the diameter of a single pMUT element and the edge-to-edge gap were 120 μm, and the size of a pMUT array was 2.27 × 6.84 mm, to be placed at the bottom of a Transwell. The measured resonance frequency of a single pMUT element was 1.48 ± 0.13 MHz and the measured acoustic intensity of the pMUT array was 0.15 ± 0.03 MPa at 1 mm away from the transducer...
September 19, 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28928844/inhibitory-effects-of-low-intensity-pulsed-ultrasound-sonication-on-the-proliferation-of-osteosarcoma-cells
#3
Toshihiro Matsuo, Keiji Sato, Takuya Matsui, Shigeyuki Sawada, Yoshitaka Muramatsu, Katsuhisa Kawanami, Masataka Deie
To date, there is limited data on the biological effects of low-intensity pulsed ultrasound (LIPUS) on primary malignant bone tumors. The purpose of the present study was to investigate the antitumor effects of LIPUS on osteosarcoma cells. The effects of LIPUS on cell viability, induction of apoptosis, mitochondrial membrane potential and intracellular signaling molecules in the LM8 osteosarcoma cell line were investigated. LIPUS inhibited cell viability (P=0.0022) and mitochondrial membrane potential (P=0...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28928588/patient-with-persistent-low-oxygen-saturation-for-emergency-cesarean-section
#4
Shivali Panwar, Kirti Nath Saxena, Prachi Gaba
A 24-year-old woman with previous undiagnosed congenital methemoglobinemia presented for the emergency cesarean section in view of fetal distress. The patient had a persistent low oxygen saturation on pulse oximetry with normal heart rate and blood pressure. Arterial blood gas values were normal. The patient was asymptomatic and respiratory and cardiovascular system examination was normal. The patient underwent cesarean section under general anesthesia and was shifted to the Intensive Care Unit postoperatively...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28926276/polypyrrole-coated-perfluorocarbon-nanoemulsions-as-a-sono-photoacoustic-contrast-agent
#5
David Shicheng Li, Soon Joon Yoon, Ivan Pelivanov, M Frenz, Matthew O'Donnell, Lilo D Pozzo
A new contrast agent for combined photoacoustic and ultrasound imaging is presented. It has a liquid perfluorocarbon (PFC) core of about 250 nm diameter coated by a 30 nm thin polypyrrole (PPy) doped polymer shell emulsion which represents a broadband absorber covering the visible and near-infrared ranges (peak optical extinction at 1050 nm). When exposed to a sufficiently high intensity optical or acoustic pulse, the droplets vaporize to form microbubbles providing a strong increase in imaging sensitivity and specificity...
September 19, 2017: Nano Letters
https://www.readbyqxmd.com/read/28925734/a-pilot-treatment-study-for-mild-traumatic-brain-injury-neuroimaging-changes-detected-by-meg-after-low-intensity-pulse-based-transcranial-electrical-stimulation
#6
Ming-Xiong Huang, Ashley Robb Swan, Annemarie Angeles Quinto, Scott Matthews, Deborah L Harrington, Sharon Nichols, Barry J Bruder, Corey C Snook, Charles W Huang, Dewleen G Baker, Roland R Lee
BACKGROUND: Mild traumatic brain injury (mTBI) is a leading cause of sustained impairments in military service members, Veterans, and civilians. However, few treatments are available for mTBI, partially because the mechanism of persistent mTBI deficits is not fully understood. METHODS: We used magnetoencephalography (MEG) to investigate neuronal changes in individuals with mTBI following a passive neurofeedback-based treatment programme called IASIS. This programme involved applying low-intensity pulses using transcranial electrical stimulation (LIP-tES) with electroencephalography monitoring...
September 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28919243/drugs-do-we-need-them-applications-of-non-pharmaceutical-therapy-in-anterior-eye-disease-a-review
#7
REVIEW
Priyanka Mandal, Mohammad A Khan, Sunil Shah
Natural products have been in use long before the introduction of modern drug therapies and are still used in various communities worldwide for the treatment of anterior eye disease. The aim of this review is to look at the current non-pharmaceutical modalities that have been tried and assess the body of existing evidence behind them. This includes alternative medicine, existing non-pharmaceutical therapy and more recent low and high tech solutions. A detailed search of all available databases including MEDLINE, Pubmed and Google was made to look for English-language studies for complementary and alternative treatment modalities (CAM), natural therapies and new modalities for anterior eye disease such as blepharitis, dry eye and microbial keratitis...
September 14, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28910407/the-spectral-features-of-eeg-responses-to-transcranial-magnetic-stimulation-of-the-primary-motor-cortex-depend-on-the-amplitude-of-the-motor-evoked-potentials
#8
Matteo Fecchio, Andrea Pigorini, Angela Comanducci, Simone Sarasso, Silvia Casarotto, Isabella Premoli, Chiara-Camilla Derchi, Alice Mazza, Simone Russo, Federico Resta, Fabio Ferrarelli, Maurizio Mariotti, Ulf Ziemann, Marcello Massimini, Mario Rosanova
Transcranial magnetic stimulation (TMS) of the primary motor cortex (M1) can excite both cortico-cortical and cortico-spinal axons resulting in TMS-evoked potentials (TEPs) and motor-evoked potentials (MEPs), respectively. Despite this remarkable difference with other cortical areas, the influence of motor output and its amplitude on TEPs is largely unknown. Here we studied TEPs resulting from M1 stimulation and assessed whether their waveform and spectral features depend on the MEP amplitude. To this aim, we performed two separate experiments...
2017: PloS One
https://www.readbyqxmd.com/read/28904322/a-preliminary-study-of-effects-of-low-intensity-pulsed-ultrasound-lipus-irradiation-on-dentoalveolar-ankylosis
#9
Tomoyasu Kiyokawa, Mitsuru Motoyoshi, Mizuki Inaba, Remi Sano, Akari Saiki, Go Torigoe, Masatake Asano, Noriyoshi Shimizu
The purpose of this experiment was to investigate whether low-intensity pulsed ultrasound (LIPUS) irradiation can inhibit dentoalveolar ankylosis in transplanted rat teeth. LIPUS irradiation (the pulsed ultrasound signal had a frequency of 3.0 MHz, a spatial average intensity of 30 mW/cm(2), and a pulse ratio of 1:4) was performed on the face over the re-planted teeth of rats for 4 weeks. After the rats were euthanized, we measured mobility (Periotest value [PTV]) of the transplanted and control teeth using a Periotest...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28893266/myocardial-performance-index-in-female-athletes
#10
Zahraa Alsafi, Andreas Malmgren, Petri Gudmundsson, Martin Stagmo, Magnus Dencker
BACKGROUND: Long-term intensive training leads to morphological and mechanical changes in the heart generally known as "athlete's heart". Previous studies have suggested that the diastolic and systolic function of the ventricles is unaltered in athletes compared to sedentary. The purpose of this study was to investigate myocardial performance index (MPI) by pulsed wave Doppler (PWD) and by tissue Doppler imaging (TDI) in female elite athletes compared to sedentary controls. METHODS: The study consisted of 32 athletes (mean age 20 ± 2 years) and 34 sedentary controls (mean age 23 ± 2 years)...
September 11, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28890798/american-football-and-other-sports-injuries-may-cause-migraine-persistent-pain-decades-later-and-can-be-treated-successfully-with-electrical-twitch-obtaining-intramuscular-stimulation-etoims
#11
J Chu, S McNally, F Bruyninckx, D Neuhauser
INTRODUCTION: Autonomous twitch elicitation at myofascial trigger points from spondylotic radiculopathies-induced denervation supersensitivity can provide favourable pain relief using electrical twitch-obtaining intramuscular stimulation (ETOIMS). AIM: To provide objective evidence that ETOIMS is safe and efficacious in migraine and persistent pain management due to decades-old injuries to head and spine from paediatric American football. METHODS AND MATERIALS: An 83-year-old mildly hypertensive patient with 25-year history of refractory migraine and persistent pain self-selected to regularly receive fee-for-service ETOIMS 2/week over 20 months...
April 2017: BMJ Innovations
https://www.readbyqxmd.com/read/28883516/effects-of-low-intensity-pulsed-electromagnetic-fields-on-bone-microarchitecture-mechanical-strength-and-bone-turnover-in-type-2-diabetic-db-db-mice
#12
Jianjun Li, Zhaobin Zeng, Yantao Zhao, Da Jing, Chuhua Tang, Yin Ding, Xue Feng
Type 2 diabetic patients have impaired bone quality, leading to increased fracture risk. Substantial evidence demonstrates that pulsed electromagnetic fields (PEMF) could resist osteopenia/osteoporosis induced by estrogen deficiency and disuse. However, the effects of PEMF on osteopenia/osteoporosis associated with diabetes, especially for more prevalent type 2 diabetes, remain poorly understood. We herein investigated the skeletal effects and mechanisms of PEMF (15 Hz, 20 Gs) on leptin receptor-deficient db/db mice with typical type 2 diabetic symptoms...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28878232/holographic-writing-of-ink-based-phase-conjugate-nanostructures-via-laser-ablation
#13
Muhammad Waqas Khalid, Rajib Ahmed, Ali K Yetisen, Bader AlQattan, Haider Butt
The optical phase conjugation (OPC) through photonic nanostructures in coherent optics involves the utilization of a nonlinear optical mechanism through real-time processing of electromagnetic fields. Their applications include spectroscopy, optical tomography, wavefront sensing, and imaging. The development of functional and personalized holographic devices in the visible and near-infrared spectrum can be improved by introducing cost-effective, rapid, and high-throughput fabrication techniques and low-cost recording media...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28876129/relationship-between-occupational-physical-activity-and-subclinical-vascular-damage-in-moderate-altitude-dwellers
#14
Kristian Ujka, Rosa Maria Bruno, Luca Bastiani, Eva Bernardi, Paolo Sdringola, Nenad Dikic, Bikash Basyal, Sanjeeb Sundarshan Bhandari, Buddha Basnyat, Annalisa Cogo, Lorenza Pratali
Ujka, Kristian, Rosa Maria Bruno, Luca Bastiani, Eva Bernardi, Paolo Sdringola, Nenad Dikic, Bikash Basyal, Sanjeeb Sundarshan Bhandari, Buddha Basnyat, Annalisa Cogo, and Lorenza Pratali. Relationship between occupational physical activity and subclinical vascular damage in moderate-altitude dwellers. High Alt Med Biol. 18:249-257, 2017. BACKGROUND: Occupational physical activity (OPA) has been associated with increased cardiovascular (CV) events. The aim of this study was to investigate the association between OPA and markers of subclinical vascular damage among a moderate-altitude population living in the rural village of Chaurikharka (Nepal; 2600 m sea level)...
September 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28868339/low-frequency-and-low-intensity-ultrasound-irradiation-to-the-forearm-improves-an-index-of-arterial-stiffness-in-subjects-with-type-2-diabetes-and-hypertension
#15
Katsunori Nonogaki, Mari Murakami, Tomoe Yamazaki, Naohiko Nonogaki
OBJECTIVES: The arterial pressure-volume index (API) is a non-invasive assessment of arterial stiffness, and is suggested as a useful predictor of future cardiovascular events. The aim of the present study was to determine the effects of low-frequency and low-intensity ultrasound applied to the forearm for 10 min on the API in Japanese subjects with type 2 diabetes and hypertension. METHODS: We examined the effects of low-frequency and low-intensity ultrasound (800 kHz, 25 mW/cm(2)) applied to the forearm for 10 min on the API, blood pressure (BP) and pulse rate in 40 Japanese subjects (13 men and 27 women; mean age ± SE, 70 ± 2 years) with type 2 diabetes and hypertension, who had the API > 30 and systolic BP > 140 mmHg at a clinic visit...
September 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28866219/effect-of-low-intensity-pulsed-ultrasound-on-the-biological-behavior-of-osteoblasts-on-porous-titanium-alloy-scaffolds-an-in-vitro-and-in-vivo-study
#16
Hongjuan Cao, Lifang Feng, Zhenxian Wu, Wentao Hou, Shujun Li, Yulin Hao, Lin Wu
Low-intensity pulsed ultrasound (LIPUS) has been used in patients with fresh fractures, delayed union and non-union to enhance bone healing and improve functional outcome. However, there were few studies concerning the effects of LIPUS on the biological behavior of osteoblasts on porous scaffolds. This study aimed to evaluate the effects of LIPUS on the biological behavior of osteoblasts on porous titanium-6aluminum-4vanadium (Ti6Al4V) alloy scaffolds in vitro and in vivo. Scaffolds were randomly divided into an ultrasound group and a control group...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28863673/development-of-cable-fed-flash-x-ray-fxr-system
#17
Rakhee Menon, S Mitra, A S Patel, R Kumar, G Singh, K Senthil, Ranjeet Kumar, T S Kolge, Amitava Roy, S Acharya, D Biswas, Archana Sharma
Flash X-ray sources driven by pulsed power find applications in industrial radiography, and a portable X-ray source is ideal where the radiography needs to be taken at the test site. A compact and portable flash X-ray (FXR) system based on a Marx generator has been developed with the high voltage fed to the FXR tube via a cable feed-through arrangement. Hard bremsstrahlung X-rays of few tens of nanosecond duration are generated by impinging intense electron beams on an anode target of high Z material. An industrial X-ray source is developed with source size as low as 1 mm...
August 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28862330/defining-the-neural-fulcrum-for-chronic-vagus-nerve-stimulation-implications-for-integrated-cardiac-control
#18
Jeffrey L Ardell, Heath Nier, Mathew Hammer, E Marie Southerland, Christopher L Ardell, Eric Beaumont, Bruce H KenKnight, J Andrew Armour
BACKGROUND: Vagus nerve stimulation (VNS) is an emerging therapy for treatment of chronic heart failure and remains a standard of therapy in patients with treatment-resistant epilepsy. OBJECTIVE: To characterize heart rate (HR) responses (HRR) during the active phase of chronic VNS over a wide range of stimulation parameters in order to define optimal protocols for bidirectional bioelectronic control of the heart. METHODS: In normal canines, bipolar electrodes were chronically implanted on the cervical vagosympathetic trunk bilaterally with anode cephalad to cathode (n = 8, "cardiac" configuration) or with electrode positions reversed (n = 8, "epilepsy" configuration)...
September 1, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28854496/the-efficacy-and-safety-of-combination-therapy-of-low-intensity-pulsed-ultrasound-stimulation-in-the-treatment-of-unstable-both-radius-and-ulna-fractures-in-children
#19
Tsuyoshi Ota, Soichiro Itoh, Kimihiro Yamashita
BACKGROUND: There are few reports of Low-intensity pulsed ultrasound (LIPUS) treatment for fresh forearm fractures in children. OBJECTIVES: LIPUS stimulation was applied after surgery of forearm fractures in children and the efficacy and safety of combination therapy of LIPUS treatment were evaluated. PATIENTS AND METHODS: Children with both radius and ulna fracture, twenty-five diaphysis (mid-R&U) and nineteen metaphysis (dist-R&U) fractures, were treated with intramedullary nailing followed by cast and splint mobilization...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28842627/enhancement-of-mesenchymal-stem-cell-chondrogenesis-with-short-term-low-intensity-pulsed-electromagnetic-fields
#20
Dinesh Parate, Alfredo Franco-Obregón, Jürg Fröhlich, Christian Beyer, Azlina A Abbas, Tunku Kamarul, James H P Hui, Zheng Yang
Pulse electromagnetic fields (PEMFs) have been shown to recruit calcium-signaling cascades common to chondrogenesis. Here we document the effects of specified PEMF parameters over mesenchymal stem cells (MSC) chondrogenic differentiation. MSCs undergoing chondrogenesis are preferentially responsive to an electromagnetic efficacy window defined by field amplitude, duration and frequency of exposure. Contrary to conventional practice of administering prolonged and repetitive exposures to PEMFs, optimal chondrogenic outcome is achieved in response to brief (10 minutes), low intensity (2 mT) exposure to 6 ms bursts of magnetic pulses, at 15 Hz, administered only once at the onset of chondrogenic induction...
August 25, 2017: Scientific Reports
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