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https://www.readbyqxmd.com/read/28807447/role-of-reactive-oxygen-species-during-low-intensity-pulsed-ultrasound-application-in-mc-3-t3-e1-pre-osteoblast-cell-culture
#1
Harmanpreet Kaur, Arno G Siraki, Hasan Uludağ, Douglas N Dederich, Patrick Flood, Tarek El-Bialy
We evaluated the activation of mitogen-activated protein kinase (MAPK) activation through reactive oxygen species (ROS) by application of low-intensity ultrasound (LIPUS) to MC-3 T3 E1 pre-osteoblasts. The cells were subjected to one LIPUS application for either 10 or 20 min, and the control group was exposed to a sham transducer. For ROS inhibition, 10 μM diphenylene iodonium (DPI) was added to the cells an hour before LIPUS application. Samples were collected 1, 3, 6, 12 and 24 h after LIPUS application, and cells were evaluated for ROS generation, cell viability, gene expression and MAPK activation by immunoblot analyses...
August 11, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28805825/the-processing-and-heterostructuring-of-silk-with%C3%A2-light
#2
Mehra S Sidhu, Bhupesh Kumar, Kamal P Singh
Spider silk is a tough, elastic and lightweight biomaterial, although there is a lack of tools available for non-invasive processing of silk structures. Here we show that nonlinear multiphoton interactions of silk with few-cycle femtosecond pulses allow the processing and heterostructuring of the material in ambient air. Two qualitatively different responses, bulging by multiphoton absorption and plasma-assisted ablation, are observed for low- and high-peak intensities, respectively. Plasma ablation allows us to make localized nanocuts, microrods, nanotips and periodic patterns with minimal damage while preserving molecular structure...
August 14, 2017: Nature Materials
https://www.readbyqxmd.com/read/28804549/treatment-effect-of-low-intensity-pulsed-ultrasound-on-leukopenia-induced-by-cyclophosphamide-in-rabbits
#3
Baoru Liu, Yueping Luo, Dong Luo, Weichen Zhou, Yu Zhang, Ruixin He, Junshu Li, Yong Wang, Yan Wang, Wenzhi Chen
OBJECTIVE: This study aims to examine the effects of low intensity pulsed ultrasound (LIPUS) on leukopenia induced by cyclophosphamide in a rabbit model. METHODS: The leukopenia model in New Zealand rabbit was established by injecting cyclophosphamide into the ear vein. Forty leukopenia model rabbits were randomly allocated to control group (n = 20) and LIPUS group (n = 20). LIPUS group underwent 20 minutes of daily ultrasound treatment at femoral metaphysis for 7 days while control group received sham treatment...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28799370/nucleation-in-food-colloids
#4
Malcolm J W Povey
Nucleation in food colloids has been studied in detail using ultrasound spectroscopy. Our data show that classical nucleation theory (CNT) remains a sound basis from which to understand nucleation in food colloids and analogous model systems using n-alkanes. Various interpretations and modifications of CNT are discussed with regard to their relevance to food colloids. Much of the evidence presented is based on the ultrasound velocity spectrometry measurements which has many advantages for the study of nucleating systems compared to light scattering and NMR due to its sensitivity at low solid contents and its ability to measure true solid contents in the nucleation and early crystal growth stages...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28775272/53-attosecond-x-ray-pulses-reach-the-carbon-k-edge
#5
Jie Li, Xiaoming Ren, Yanchun Yin, Kun Zhao, Andrew Chew, Yan Cheng, Eric Cunningham, Yang Wang, Shuyuan Hu, Yi Wu, Michael Chini, Zenghu Chang
The motion of electrons in the microcosm occurs on a time scale set by the atomic unit of time-24 attoseconds. Attosecond pulses at photon energies corresponding to the fundamental absorption edges of matter, which lie in the soft X-ray regime above 200 eV, permit the probing of electronic excitation, chemical state, and atomic structure. Here we demonstrate a soft X-ray pulse duration of 53 as and single pulse streaking reaching the carbon K-absorption edge (284 eV) by utilizing intense two-cycle driving pulses near 1...
August 4, 2017: Nature Communications
https://www.readbyqxmd.com/read/28772237/low-intensity-laser-therapy-efficacy-evaluation-in-mice-subjected-to-acute-arthritis-condition
#6
Bianca F Trawitzki, Lothar Lilge, Fellipe A T de Figueiredo, Ana Paula Macedo, João Paulo M Issa
Acute arthritis is an inflammation that affects many joints. The principal treatment options comprise drugs (corticosteroids), invasive and painful surgery. The objective of this study was to evaluate the efficacy of low intensity laser therapy (LILT), a non-invasive treatment, in a murine model of acute inflammation model. 48 mice received a synovial injection of Zymosan A into one knee. Mice were treated with LILT by three different wavelengths, either as a single (S) or dual (D) application immediately after the injury or after 24h following initiation of an inflammatory response...
July 26, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28768288/reliability-and-validity-of-a-smartphone-paired-pulse-oximeter-for-screening-of-critical-congenital-heart-defects-in-newborns
#7
Maurice J Huizing, Eduardo Villamor-Martínez, Ingrid A Chavagne, Ward Y Vanagt, Marc A E Spaanderman, Eduardo Villamor
BACKGROUND: Barriers to widespread implementation of pulse oximetry screening of critical congenital heart defects (CCHD) in newborns include increasing trends of out-of-hospital births and cost of equipment. In recent years, smartphone-compatible pulse oximeters have appeared on the market, but the validity of such devices in the setting of CCHD screening has not been evaluated. OBJECTIVES: To compare the performance in CCHD screening of a smartphone-paired pulse oximeter (Masimo iSpO2-Rx™) and a hospital-grade pulse oximeter (Masimo Radical-7™)...
August 3, 2017: Neonatology
https://www.readbyqxmd.com/read/28766738/major-shifts-in-amazon-wildlife-populations-from-recent-climatic-intensification
#8
Richard Bodmer, Pedro Mayor, Miguel Antunez, Kimberlyn Chota, Tula Fang, Pablo Puertas, Marlini Pittet, Maire Kirkland, Mike Walkey, Claudia Rios, Pedro Perez-Peña, Peter Henderson, William Bodmer, Andy Bicerra, Joseph Zegarra, Emma Docherty
In the western Amazon basin, recent intensification of river level cycles has increased flooding during the wet seasons and decreased precipitation during the dry season. Greater than normal floods occurred in 2009 and in all years from 2011-2015 during high water seasons, and a drought occurred during the 2010 low water season. During these years, we surveyed populations of terrestrial, arboreal and aquatic wildlife in a seasonally flooded Amazonian forest to study the consequences of intensification of climatic fluctuations to wildlife populations and in turn resource use by traditional people...
August 2, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28763567/low-intensity-extracorporeal-shock-wave-therapy-promotes-myogenesis-through-perk-atf4-pathway
#9
Bohan Wang, Jun Zhou, Lia Banie, Amanda B Reed-Maldonado, Hongxiu Ning, Zhihua Lu, Yajun Ruan, Tie Zhou, Hsun Shuan Wang, Byung Seok Oh, Guifang Wang, Stanley Lei Qi, Guiting Lin, Tom F Lue
AIM: Stress urinary incontinence (SUI) is a significant health problem for women. Treatments employing muscle derived stem cells (MDSCs) may be a promising approach to this prevalent, bothersome condition, but these treatments are invasive and require collection of cells from one site for injection into another. It is also unknown whether or not these cells establish themselves and function as muscle cells in the target tissues. Alternatively, low-intensity extracorporeal shock wave therapy (Li-ESWT) is non-invasive and has shown positive outcomes in the treatment of multiple musculoskeletal disorders, but the biological effects responsible for clinical success are not yet well understood...
August 1, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28763448/frequency-sensitive-mechanism-in-low-intensity-ultrasound-enhanced-bioeffects
#10
April D Miller, Abdoulkadri Chama, Tobias M Louw, Anuradha Subramanian, Hendrik J Viljoen
This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regulatory markers for cellular response to external stimuli. However, ERK phosphorylation displayed no frequency dependency, suggesting that the biochemical mechanisms involved in enhanced gene expression is downstream of ERK phosphorylation...
2017: PloS One
https://www.readbyqxmd.com/read/28762588/an-investigation-of-shock-wave-therapy-and-low-intensity-pulsed-ultrasound-on-fracture-healing-under-reduced-loading-conditions-in-an-ovine-model
#11
Benjamin C Gadomski, Kirk C McGilvray, Jeremiah T Easley, Ross H Palmer, Jian Jiao, Xiaofei Li, Yi-Xian Qin, Christian M Puttlitz
The use of shock wave therapy (SWT) and low-intensity pulsed ultrasound (LIPUS) as countermeasures to the inhibited fracture healing experienced during mechanical unloading was investigated by administering treatment to the fracture sites of mature, female, Rambouillet Columbian ewes exposed to partial mechanical unloading or full gravitational loading. The amount of fracture healing experienced by the treatment groups was compared to controls in which identical surgical and testing protocols were administered except for SWT or LIPUS treatment...
August 1, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28761427/high-frequency-and-brief-pulse-stimulation-pulses-terminate-cortical-electrical-stimulation-induced-afterdischarges
#12
Zhi-Wei Ren, Yong-Jie Li, Tao Yu, Duan-Yu Ni, Guo-Jun Zhang, Wei Du, Yuan-Yuan Piao, Xiao-Xia Zhou
Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of different brief-pulse stimulation frequencies (5, 50 and 100 Hz) on cortical electrical stimulation-induced afterdischarges in 10 patients with refractory epilepsy. Results demonstrated that brief-pulse stimulation could terminate cortical electrical stimulation-induced afterdischarges in refractory epilepsy patients...
June 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28754573/enhanced-microbubbles-assisted-cleaning-of-diesel-contaminated-sand
#13
Ashutosh Agarwal, Yu Liu
In this article, we investigated the effect of low intensity pulsed ultrasound (US), temperature and salinity on cleaning efficacy of fine bubbles with diameter <50μm for diesel contaminated sands. About 47% and 76% diesel removal was achieved from 10% (w/w) diesel contaminated fine and medium sands respectively, after 30min treatment with 40kHz low intensity intermittent pulsed US together with MBs in contrast to 41% and 68% diesel removal while treatment with MBs alone. The effect of high temperature was found to be prominent during the initial stages of cleaning...
July 25, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28749481/evaluation-of-critical-congenital-heart-defects-screening-using-pulse-oximetry-in-the-neonatal-intensive-care-unit
#14
K Van Naarden Braun, R Grazel, R Koppel, S Lakshminrusimha, J Lohr, P Kumar, B Govindaswami, M Giuliano, M Cohen, N Spillane, P Jegatheesan, D McClure, D Hassinger, O Fofah, S Chandra, D Allen, R Axelrod, J Blau, S Hudome, E Assing, L F Garg
OBJECTIVE: To evaluate the implementation of early screening for critical congenital heart defects (CCHDs) in the neonatal intensive care unit (NICU) and potential exclusion of sub-populations from universal screening. STUDY DESIGN: Prospective evaluation of CCHD screening at multiple time intervals was conducted in 21 NICUs across five states (n=4556 infants). RESULTS: Of the 4120 infants with complete screens, 92% did not have prenatal CHD diagnosis or echocardiography before screening, 72% were not receiving oxygen at 24 to 48 h and 56% were born ⩾2500 g...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28747606/effective-therapy-with-infliximab-for-clinically-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-in-an-infant-with-kawasaki-disease
#15
Yoshie Kurokawa, Hiroshi Masuda, Tohru Kobayashi, Hiroshi Ono, Hitoshi Kato, Ken-Ichi Imadome, Jun Abe, Yuichi Abe, Shuichi Ito, Akira Ishiguro
  Kawasaki disease (KD) is a systemic vasculitis in infants. In KD, encephalopathy is rarely (0.1%) associated, however, clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) has previously been reported in some pediatric patients. Here, we report on a 2-year-old girl who had KD complicated with MERS. The patient experienced generalized clonic convulsion and prolonged consciousness disturbance with fever for 2 days. Her head MRI showed a high signal intensity lesion in the splenium of the corpus callosum in diffusion-weighted images, and low apparent diffusion coefficient (ADC) values on day 3...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28742783/end-expiratory-occlusion-test-predicts-fluid-responsiveness-in-patients-with-protective-ventilation-in-the-operating-room
#16
Matthieu Biais, Mathilde Larghi, Jeremy Henriot, Hugues de Courson, Musa Sesay, Karine Nouette-Gaulain
BACKGROUND: End-expiratory occlusion test (EEOT) has been proposed to predict fluid responsiveness in mechanically ventilated intensive care unit patients. The utility of this test during low-tidal-volume ventilation remains uncertain. This study aimed to determine whether hemodynamic variations induced by EEOT could predict the effect of volume expansion in patients with protective ventilation in the operating room. METHODS: Forty-one patients undergoing neurosurgery were included...
July 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28741866/a-review-of-available-laser-and-intense-light-source-home-devices-a-dermatologist-s-perspective
#17
REVIEW
Margit Lw Juhász, Melissa K Levin, Ellen S Marmur
BACKGROUND: Home optical devices are becoming an increasingly popular treatment modality sought out by patients for dermatologic pathologies such as acne, hair removal and anti-aging, as these devices are a low-cost and convenient therapy choice. METHODS: An Internet search using PubMed.gov was completed with search terms, "home device dermatology," "home device acne," "home device hair" or "hair removal," and "home device aging." RESULTS: Currently, there are multiple home optical devices available on the market...
July 25, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28741320/differential-intensity-dependent-effects-of-pulsed-electromagnetic-fields-on-rankl-induced-osteoclast-formation-apoptosis-and-bone-resorbing-ability-in-raw264-7-cells
#18
Pan Wang, Juan Liu, Yuefan Yang, Mingming Zhai, Xi Shao, Zedong Yan, Xuhui Zhang, Yan Wu, Lu Cao, Bingdong Sui, Erping Luo, Da Jing
Pulsed electromagnetic fields (PEMF) have been proven to be effective for promoting bone mass and regulating bone turnover both experimentally and clinically. However, the exact mechanisms for the regulation of PEMF on osteoclastogenesis as well as optical exposure parameters of PEMF on inhibiting osteoclastic activities and functions remain unclear, representing significant limitations for extensive scientific application of PEMF in clinics. In this study, RAW264.7 cells incubated with RANKL were exposed to 15 Hz PEMF (2 h/day) at various intensities (0...
July 24, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28738301/effects-of-an-in-situ-diesel-oil-spill-on-oxidative-stress-in-the-clam-anomalocardia-flexuosa
#19
Adriana E Sardi, Paul E Renaud, Gisele C Morais, César C Martins, Paulo da Cunha Lana, Lionel Camus
Intensive exploitation and transport of oil and derivatives are increasing the risk of coastal contamination by either dramatic disasters or diffuse sources. Tools for monitoring diffuse contamination, such as diesel oil that leaks from marine vessels are much needed. We experimentally tested the efficiency of antioxidant biomarkers as indicators of chronic exposure to diesel oil in a mudflat from the subtropical Bay of Paranaguá, in southern Brazil. We examined the effects of three successive diesel oil spills, with two weeks of recovery time between exposures, on the edible clam Anomalocardia flexuosa...
July 21, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28735428/effects-of-low-intensity-pulsed-ultrasound-on-soft-tissue-micro-circulation-in-the-foot
#20
Anna Katharina Kösters, Bergita Ganse, Boyko Gueorguiev, Kajetan Klos, Ali Modabber, Sven Nebelung, Bong-Sung S Kim, Matthias Knobe
PURPOSE: Low-intensity pulsed ultrasound (LIPUS) has been shown to accelerate bone healing and is considered to increase blood flow. The aim of this study was to assess changes in micro-circulation of the foots' soft tissue in response to LIPUS intervention. We hypothesised improved micro-circulation in response to LIPUS. METHODS: Micro-circulation was assessed in 2 mm and 8 mm-deep skin of 50 healthy volunteers using non-invasive laser-doppler spectrophotometry (O2C-device)...
July 22, 2017: International Orthopaedics
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