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https://www.readbyqxmd.com/read/29324062/four-day-pulse-of-sodium-cromoglycate-modulates-pulmonary-vessel-wall-remodeling-during-21-day-hypoxia-in-rats
#1
Tomáš Novotný, Jiří Uhlík, Luděk Vajner
AIM OF THE STUDY: Remodeling of pulmonary resistance arteries in rats due to 4-day hypoxia could be successfully suppressed by sodium cromoglycate. In this study, we tested the difference in the suppression between two distinct time patterns of cromoglycate administration during 21-day hypoxia. In the experiment, we focused on some details in both smooth muscle cells and extracellular matrix of pulmonary arterial walls. METHODS: During 21-day hypoxia, rats were treated with sodium cromoglycate either in the first four days or in the last four days...
January 11, 2018: Experimental Lung Research
https://www.readbyqxmd.com/read/29321926/lung-injury-associated-with-electronic-cigarettes-inhalation-diagnosed-by-transbronchial-lung-biopsy
#2
Masayuki Itoh, Kazutetsu Aoshiba, Yoriko Herai, Hiroyuki Nakamura, Tamiko Takemura
A 46-year-old healthy man developed respiratory distress, night sweats, fever, and weight loss after using electronic cigarettes (e-cigs) for approximately 1 month. He presented to the hospital when the symptoms worsened 2 months after onset. The findings of bronchoalveolar lavage (BAL) fluid examination and the following transbronchial lung biopsy examination led to the diagnosis of acute alveolitis: intra-alveolar fibrosis accompanied with exudate containing abundant lipid-laden macrophages, eosinophils, and neutrophils...
January 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29295735/photodynamic-therapy-interventions-in-facial-photodamage-a-systematic-review
#3
G Sanclemente, V Ruiz-Cañas, J M Miranda, A P Ferrín, P A Ramirez, G N Hernandez
INTRODUCTION: Photodynamic therapy (PDT) involves the combination of a light source and a photosensitizing agent to induce tissue damage via the generation of singlet oxygen. Although topical PDT has been approved for other indications, its use in facial photodamage is uncertain. AIMS: To assess the efficacy and safety of PDT in facial skin photoaging. METHODS: All randomized clinical trials (RCTs) evaluating the efficacy and safety of any form of topical PDT for the treatment of facial photodamage (dermatoheliosis) or photoaging in patients older than 18 years, were included...
December 30, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29288596/ultrasound-enhanced-drug-delivery-for-treatment-of-onychomycosis
#4
Alina Kline-Schoder, Zung Le, Vesna Zderic
OBJECTIVES: The aim of our study was to determine the effectiveness of using ultrasound (US) to increase the permeability of the nail, with the goal of improving outcomes in the treatment of onychomycosis. METHODS: Porcine nails were used because of their similarity to human nails. A hydrophilic blue dye was used as a drug-mimicking compound. Two sets of experiments were performed: luminosity experiments to assess the dye levels inside the nail after US and sham treatments and diffusion cell experiments for determination of changes in nail permeability due to US application...
December 30, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29287457/pulsed-electric-field-processing-reduces-the-oxalate-content-of-oca-oxalis-tuberosa-tubers-while-retaining-starch-grains-and-the-general-structural-integrity-of-tubers
#5
Tingting Liu, David John Burritt, Graham T Eyres, Indrawati Oey
The aims of this research were to investigate if pulsed electric field (PEF) treatments caused cellular/structural alterations in Oxalis tuberosa (oca) tubers and if PEF treatment could reduce tuber oxalate levels. Whole oca tubers were treated with PEF at different electric field strengths up to 1.2 kV/cm. PEF treatments above 0.5 kV/cm caused tubers to soften, but differences in the electrical properties of the tuber tissues led to an uneven PEF effect with the tuber inner cores softening more than the middle regions...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29286244/kinetics-of-the-reactions-between-the-criegee-intermediate-ch2oo-and-alcohols
#6
Sara V Tadayon, Elizabeth S Foreman, Craig Murray
Reactions of the simplest Criegee intermediate (CH2OO) with a series of alcohols have been studied in a flash photolysis flow reactor. Laser photolysis of diiodomethane at 355 nm in the presence of molecular oxygen was used to produce CH2OO, and the absolute number densities were determined as a function of delay time from analysis of broadband transient absorption spectra obtained using a pulsed LED. The kinetics for the reactions of CH2OO with methanol, ethanol, and 2-propanol were measured under pseudo-first-order conditions at 295 K, yielding rate constants of (1...
December 29, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29261126/remotely-exploring-deeper-into-matter-by-non-contact-detection-of-audible-transients-excited-by-laser-radiation
#7
Javier Moros, Inmaculada Gaona, J Javier Laserna
An acoustic spectroscopic approach to detect contents within different packaging, with substantially wider applicability than other currently available subsurface spectroscopies, is presented. A frequency-doubled Nd:YAG (neodymium-doped yttrium aluminum garnet) pulsed laser (13 ns pulse length) operated at 1 Hz was used to generate the sound field of a two-component system at a distance of 50 cm. The acoustic emission was captured using a unidirectional microphone and analyzed in the frequency domain. The focused laser pulse hitting the system, with intensity above that necessary to ablate the irradiated surface, transferred an impulsive force which led the structure to vibrate...
December 20, 2017: Sensors
https://www.readbyqxmd.com/read/29238021/-granulomatosis-with-polyangiitis-complicated-with-gastrointestinal-perforation-a-case-report-and-review-of-literature
#8
Takao Kiboshi, Kentaro Isoda, Koichi Furukawa, Tomoyuki Wakahara, Kenichiro Otani, Kayo Ueda, Junichi Konma, Kazuhiro Teramura, Nozomi Ueno, Hiroshi Fujiwara, Takeshi Shoda
  A 51-year-old man was detected nasal bleeding, multiple pulmonary nodule and mass, urinalysis abnormality, renal involvement and high titer of proteinase 3-anti-neutrophil cytoplasmic antibody (PR3-ANCA), and was suspected of granulomatosis with polyangiitis and initiated with steroid pulse therapy. On the day after the start of steroid pulse therapy, generalized peritonitis due to ileal perforation occurred, and emergency ileectomy and peritonitis surgery were performed. Induction therapy with steroid pulse therapy, plasma exchange and intravenous cyclophosphamide therapy (IVCY) and maintenance therapy with glucocorticoid and azathioprine led to good therapeutic outcomes...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29236899/mechanical-behavior-of-yttria-stabilized-tetragonal-zirconia-polycrystal-effects-of-different-aging-regimens
#9
Luís Felipe Guilardi, Gabriel Kalil Rocha Pereira, Vinícius Felipe Wandscher, Marília Pivetta Rippe, Luiz Felipe Valandro
This study aimed to characterize and compare the effect of different aging regimens on surface characteristic (topography and roughness), structural stability (phase transformation) and mechanical performance (Weibull analysis) of a Y-TZP ceramic. Discs (15 × 1.2 mm; VITA In-Ceram YZ) were prepared according to ISO 6872-2015 for biaxial flexural strength testing and randomly assigned into five groups (n = 30): as-sintered, no aging treatment (CTRL); 20 h in autoclave at 134°C, 2 bar pressure (AUT); intermittent mechanical loading at 20 Hz/106 load pulses (MechLoad); AUT followed by MechLoad (AUT+MechLoad); and storage in distilled water at 37°C, for 1 year (STO)...
December 7, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/29236208/effects-of-photosynthetic-photon-flux-density-frequency-duty-ratio-and-their-interactions-on-net-photosynthetic-rate-of-cos-lettuce-leaves-under-pulsed-light-explanation-based-on-photosynthetic-intermediate-pool-dynamics
#10
Tomohiro Jishi, Ryo Matsuda, Kazuhiro Fujiwara
Square-wave pulsed light is characterized by three parameters, namely average photosynthetic photon flux density (PPFD), pulsed-light frequency, and duty ratio (the ratio of light-period duration to that of the light-dark cycle). In addition, the light-period PPFD is determined by the averaged PPFD and duty ratio. We investigated the effects of these parameters and their interactions on net photosynthetic rate (P n) of cos lettuce leaves for every combination of parameters. Averaged PPFD values were 0-500 µmol m-2 s-1...
December 13, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/29234601/the-characterization-of-an-economic-and-portable-led-based-photoacoustic-imaging-system-to-facilitate-molecular-imaging
#11
Ali Hariri, Jeanne Lemaster, Junxin Wang, AnanthaKrishnan S Jeevarathinam, Daniel L Chao, Jesse V Jokerst
Photoacoustic imaging (PAI) is a non-invasive, high-resolution hybrid imaging modality that combines optical excitation and ultrasound detection. PAI can image endogenous chromophores (melanin, hemoglobin, etc.) and exogenous contrast agents in different medical applications. However, most current equipment uses sophisticated and complicated OPO lasers with tuning and stability features inconsistent with broad clinical deployment. As the number of applications of PAI in medicine increases, there is an urgent need to make the imaging equipment more compact, portable, and affordable...
March 2018: Photoacoustics
https://www.readbyqxmd.com/read/29234578/au-nanostructure-fabrication-by-pulsed-laser-deposition-in-open-air-influence-of-the-deposition-geometry
#12
Rumen G Nikov, Anna Og Dikovska, Nikolay N Nedyalkov, Georgi V Avdeev, Petar A Atanasov
We present a fast and flexible method for the fabrication of Au nanocolumns. Au nanostructures were produced by pulsed laser deposition in air at atmospheric pressure. No impurities or Au compounds were detected in the resulting samples. The nanoparticles and nanoaggregates produced in the ablated plasma at atmospheric pressure led to the formation of chain-like nanostructures on the substrate. The dependence of the surface morphology of the samples on the deposition geometry used in the experimental set up was studied...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/29233904/autologous-dendritic-cells-pulsed-with-allogeneic-tumor-cell-lysate-in-mesothelioma-from-mouse-to-human
#13
Joachim G Aerts, Pauline L de Goeje, Robin Cornelissen, Margaretha E H Kaijen-Lambers, Koen Bezemer, Cor van der Leest, Niken M Mahaweni, Andre Kunert, Ferry A L M Eskens, Cynthia Waasdorp, Eric Braakman, Bronno van der Holt, Arnold G Vulto, Rudi W Hendriks, Joost P J J Hegmans, Henk C Hoogsteden
PURPOSE: Mesothelioma has been regarded as a non-immunogenic tumor, which is also shown by the low response rates to treatments targeting the PD-1/PD-L1 axis.  Previously, we demonstrated that autologous tumor lysate-pulsed dendritic cell (DC) immunotherapy increased T-cell response towards malignant mesothelioma. However, the use of autologous tumor material hampers implementation in large clinical trials, which might be overcome by using allogeneic tumor cell lines as tumor antigen source...
December 12, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29232640/decomposition-of-ibuprofen-in-water-via-an-electrochemical-process-with-nano-sized-carbon-black-coated-carbon-cloth-as-oxygen-permeable-cathode-integrated-with-ultrasound
#14
Reza Darvishi Cheshmeh Soltani, Masumeh Mashayekhi
The main aim of the present investigation was the treatment of ibuprofen (IBP)-polluted aquatic phase using a novel oxygen-permeable cathode (OPC)-equipped electrochemical process (ECP) integrated with ultrasound (US). According to kinetic modeling, the decomposition rate of IBP by the integrated process was 3.2 × 10-2 min-1 which was significant in comparison with the OPC-equipped ECP (1.4 × 10-2 min-1) and US alone (2.4 × 10-3 min-1). Increasing the current resulted in the enhanced generation of H2O2 and consequently, improved the degradation of IBP in the solution...
December 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/29221743/ex%C3%A2-vivo-hydrodynamics-after-central-and-paracommissural-edge-to-edge-technique-a-further-step-toward-transcatheter-tricuspid-repair
#15
Sina Stock, Heidemarie Bohm, Michael Scharfschwerdt, Doreen Richardt, Roza Meyer-Saraei, Stanislav Tsvelodub, Hans-Hinrich Sievers
OBJECTIVES: Transcatheter approaches in heart valve disease became tremendously important and are currently established in the aortic position, but transcatheter tricuspid repair is still in its beginning and remains challenging. Replicating the surgical edge-to-edge technique, for example, with the MitraClip System (Abbott Vascular, Santa Clara, Calif), represents a promising option and has been reported successfully in small numbers of cases. However, up to now, few data considering the edge-to-edge technique as a transcatheter approach are available...
November 2, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29221643/respiratory-and-cardiovascular-responses-to-walking-down-a-traffic-polluted-road-compared-with-walking-in-a-traffic-free-area-in-participants-aged-60-years-and-older-with-chronic-lung-or-heart-disease-and-age-matched-healthy-controls-a-randomised-crossover
#16
Rudy Sinharay, Jicheng Gong, Benjamin Barratt, Pamela Ohman-Strickland, Sabine Ernst, Frank Kelly, Junfeng Jim Zhang, Peter Collins, Paul Cullinan, Kian Fan Chung
BACKGROUND: Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. We aimed to assess the effects on respiratory and cardiovascular responses of walking down a busy street with high levels of pollution compared with walking in a traffic-free area with lower pollution levels in older adults...
December 5, 2017: Lancet
https://www.readbyqxmd.com/read/29221380/halogen-bonding-properties-of-4-iodopyrazole-and-4-bromopyrazole-explored-by-rotational-spectroscopy-and-ab-initio-calculations
#17
Graham A Cooper, Chris Medcraft, Josh D Littlefair, Thomas J Penfold, Nicholas R Walker
The combination of halogen- and hydrogen-bonding capabilities possessed by 4-bromopyrazole and 4-iodopyrazole has led to them being described as "magic bullets" for biochemical structure determination. Laser vaporisation was used to introduce each of these 4-halopyrazoles into an argon gas sample undergoing supersonic expansion prior to the recording of the rotational spectra of these molecules by chirped-pulse Fourier transform microwave spectroscopy. Data were obtained for four isotopologues of 4-bromopyrazole and two isotopologues of 4-iodopyrazole...
December 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29220992/all-inorganic-perovskite-based-distributed-feedback-resonator
#18
Junyi Gong, Yue Wang, Sheng Liu, Pan Zeng, Xilu Yang, Rongqing Liang, Qiongrong Ou, Xiang Wu, Shuyu Zhang
Halide perovskite materials have rapidly emerged as outstanding optoelectronic materials for solar cells, light-emitting diodes (LEDs), and lasers. Compared to hybrid organic-inorganic perovskites, all-inorganic perovskites have shown unique merits that may contribute to the ultimate goal of developing electrically-pumped lasers. In this paper, we demonstrate a distributed feedback (DFB) resonator using an all-inorganic perovskite thin film as the gain medium. The film has a gain coefficient of 161.1 cm-1 and a loss coefficient of 30...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29214626/a-descriptive-analysis-of-data-from-the-department-of-defense-joint-trauma-system-prehospital-trauma-registry
#19
Stephen G Schauer, Michael D April, Jason F Naylor, Joshua J Oliver, Cord W Cunningham, Andrew D Fisher, Russ S Kotwal
The active battlefield is an environment of chaos and confusion. Depending on the scale of combat, the chaos and confusion often extend into the prehospital combat setting with multiple personnel and units involved in the chain of care of casualties. The chaos of the prehospital combat setting has led to limitations in the availability of data for performance improvement and research. The Department of Defense (DoD) Joint Trauma System (JTS) Prehospital Trauma Registry (PHTR) was developed in conjunction with the updated Tactical Combat Casualty Care (TCCC) card and a TCCC after action report (AAR), and currently serves as the prehospital repository and module of the DoD Trauma Registry (DoDTR)...
October 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/29209866/photobiomodulation-therapy-protects-skeletal-muscle-and-improves-muscular-function-of-mdx-mice-in-a-dose-dependent-manner-through-modulation-of-dystrophin
#20
Gianna Móes Albuquerque-Pontes, Heliodora Leão Casalechi, Shaiane Silva Tomazoni, Andrey Jorge Serra, Cheila de Sousa Bacelar Ferreira, Rodrigo Barbosa de Oliveira Brito, Brunno Lemes de Melo, Adriane Aver Vanin, Kadma Karênina Damasceno Soares Monteiro, Humberto Dellê, Lucio Frigo, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
This study aimed to analyze the protective effects of photobiomodulation therapy (PBMT) with combination of low-level laser therapy (LLLT) and light emitting diode therapy (LEDT) on skeletal muscle tissue to delay dystrophy progression in mdx mice (DMD mdx ). To this aim, mice were randomly divided into five different experimental groups: wild type (WT), placebo-control (DMD mdx ), PBMT with doses of 1 J (DMD mdx ), 3 J (DMD mdx ), and 10 J (DMD mdx ). PBMT was performed employing a cluster probe with 9 diodes (1 x 905nm super-pulsed laser diode; 4 x 875nm infrared LEDs; and 4 x 640nm red LEDs, manufactured by Multi Radiance Medical®, Solon - OH, USA), 3 times a week for 14 weeks...
December 5, 2017: Lasers in Medical Science
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