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Bioresorbable scaffolds

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https://www.readbyqxmd.com/read/28185417/left-main-coronary-angioplasty-of-a-9-year-old-child-with-bioresorable-vascular-scaffold
#1
Hasmukh Ravat, Swati Garekar, Vishal Changela
Familial hypercholesterolemia is an autosomal dominant disorder due to mutations in the low-density lipoprotein receptor gene, characterized by skin and tendon xanthomas, xanthelasmas, and increased risk of premature coronary artery disease. Here, we report a case of 9-year-old girl who presented with angina and dyspnoea on exertion with xanthomas and an elevated serum cholesterol and triglyceride. She had severe stenosis of the left main coronary artery (LMCA) requiring angioplasty and placement of Bioresorbable vascular scaffold (BVS)...
February 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28177449/coronary-bioresorbable-vascular-scaffold-radiopaque-marker-embolization
#2
Carlos Collet, Pannipa Suwannasom, Manuel Almeida, Yoshinobu Onuma, Patrick W Serruys
No abstract text is available yet for this article.
February 8, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28164433/coronary-artery-aneurysm-after-implantation-of-a-bioresorbable-vascular-scaffold-case-report-and-literature-review
#3
Su-Kiat Chua, Jun-Jack Cheng
A 55-year-old man underwent successful percutaneous coronary intervention for the middle left circumflex artery with a 3.5 × 28-mm bioresorbable vascular scaffold (BVS). At 18 months, follow-up coronary angiography showed ectatic change with aneurysm formation over the BVS. Optical coherence tomography revealed absence of strut continuity at the aneurysm site, in the middle of the BVS. A literature review identified nine patients with intrascaffold aneurysm, including the present patient, which developed 6-32 months after BVS implantation...
February 6, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28158421/fate-of-post-procedural-malapposition-of-everolimus-eluting-polymeric-bioresorbable-scaffold-and-everolimus-eluting-cobalt-chromium-metallic-stent-in-human-coronary-arteries-sequential-assessment-with-optical-coherence-tomography-in-absorb-japan-trial
#4
Yohei Sotomi, Yoshinobu Onuma, Jouke Dijkstra, Yosuke Miyazaki, Ken Kozuma, Kengo Tanabe, Jeffrey J Popma, Robbert J de Winter, Patrick W Serruys, Takeshi Kimura
No abstract text is available yet for this article.
January 30, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28145045/intraluminal-bioresorbable-vascular-scaffold-dismantling-with-aneurysm-formation-leading-to-very-late-thrombosis
#5
Amisha Patel, Tamim Nazif, Gregg W Stone, Ziad A Ali
Coronary artery aneurysm formation has been described in patients after the placement of first-generation drug-eluting stents (DES), but is less common with newer generation metallic stents. In contrast, coronary artery aneurysm formation may be more common with the use of bioresorbable vascular scaffolds (BVS) due to the frequent formation of evaginations in the arterial wall seen with BVS. In this article, we describe a unique case of BVS dismantling and thrombus formation leading to an acute coronary syndrome thirty-two months after initial BVS placement...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28134094/outcome-after-long-segment-stenting-with-everolimus-eluting-bioresorbable-scaffolds-focusing-on-the-concept-of-overlapping-implantation
#6
Jens Wiebe, Oliver Dörr, Christoph Liebetrau, Timm Bauer, Eva Wilkens, Hanna Ilstad, Niklas Boeder, Albrecht Elsässer, Helge Möllmann, Christian W Hamm, Holger M Nef
INTRODUCTION AND OBJECTIVES: The implantation of bioresorbable scaffolds (BRS) is an emerging technique used in percutaneous coronary interventions. Their application has been extended to more complex lesions, although evidence is only available for simple lesions. The present study evaluated scaffold implantation in long lesions, focusing on overlapping scaffolds. METHODS: We retrospectively analyzed all consecutive patients eligible for stenting with everolimus-eluting poly-L-lactic acid-based BRS with a minimum total scaffold length of 28mm, irrespective of the number of BRS used...
December 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28132761/restenosis-after-everolimus-eluting-vascular-scaffolding-angiographic-and-optical-coherence-tomography-characterization
#7
Jorge Chavarría, Javier Suárez de Lezo, Soledad Ojeda, Manuel Pan, José Segura, Francisco Mazuelos, Simona Espejo, José López, Miguel Romero, José Suárez de Lezo
INTRODUCTION AND OBJECTIVES: Coronary restenosis after bioresorbable vascular scaffold (BVS) implantation is infrequent and little information is available on the main characteristics of these lesions. The aim of this study was to assess restenotic lesions by using optical coherence tomography (OCT). METHODS: We studied 330 patients with coronary artery disease who received 398 BVS to treat 380 lesions. These patients were clinically and angiographically evaluated at follow-up and OCT was carried out on detection of restenosis...
October 27, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28130134/nanoceramics-on-osteoblast-proliferation-and-differentiation-in-bone-tissue-engineering
#8
REVIEW
Sai Nievethitha S, Subhapradha N, Saravanan D, Selvamurugan N, Wei-Bor Tsai, Srinivasan N, Murugesan R, Moorthi A
Bone, a highly dynamic connective tissue, consist of a bioorganic phase comprising osteogenic cells and proteins which lies over an inorganic phase predominantly made of CaPO4 (biological apatite). Injury to bone can be due to mechanical, metabolic or inflammatory agents also owing pathological conditions like fractures, osteomyelitis, osteolysis or cysts may arise in enameloid, chondroid, cementum, or chondroid bone which forms the intermediate tissues of the body. Bone tissue engineering (BTE) applies bioactive scaffolds, host cells and osteogenic signals for restoring damaged or diseased tissues...
January 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28119252/what-determines-long-term-outcomes-using-fully-bioresorbable-scaffolds-the-device-the-operator-or-the-lesion
#9
Kyohei Yamaji, Lorenz Räber, Stephan Windecker
No abstract text is available yet for this article.
January 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28116914/treatment-of-coronary-artery-in-stent-restenosis
#10
Damianos G Kokkinidis, Stephen W Waldo, Ehrin J Armstrong
Although drug-eluting stents (DES) have significantly reduced the incidence and prevalence of coronary in-stent restenosis (ISR), ISR still occurs in approximately 10% of patients in real-world practice. Areas covered: The development of newer generations of DES, drug-coated balloons (DCB) and increased use of intracoronary imaging have improved our treatment options for and pathophysiologic understanding of ISR. These technological advancements have also largely supplanted older modalities for treatment of ISR, such as brachytherapy, bare metal stents, conventional and cutting balloon angioplasty, and atherectomy devices...
January 31, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28115812/ivus-guided-implantation-of-bioresorbable-vascular-scaffolds-for-very-late-paclitaxel-stent-thrombosis
#11
Zhe-Zhong Lin, Wei-Ting Chang, Chun-Yen Chiang, Zhih-Cherng Chen, Po-Ming Ku
Bioresorbable vascular scaffold (BVS) implantation has been shown to be safe in patients with stable coronary disease, and effective against the thrombotic lesion and the in-stent restenosis (ISR) of the drug-eluting stent (DES). BVSs have the advantages of a snow racket concept, positive vessel remodeling, and better conformability compared with DES in acute coronary syndrome (ACS). We report on a young patient with ST-elevation myocardial infarction (STEMI) who presented to our emergency department arising from very late stent thrombosis (VLST) of a 2...
January 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28115471/two-year-outcomes-of-bioresorbable-vascular-scaffold-versus-drug-eluting-stents-in-coronary-artery-disease-a-meta-analysis
#12
Ramez Nairooz, Marwan Saad, Partha Sardar, Wilbert S Aronow
BACKGROUND: Data regarding long-term clinical outcomes with everolimus-eluting bioresorbable vascular scaffold (BVS) versus second-generation drug-eluting stents (DES) are scarce. METHODS: We searched online databases until October 2016 for studies comparing BVS versus DES reporting outcomes at 2 years of follow-up. We performed a meta-analysis comparing BVS with DES across the spectrum of coronary artery disease (CAD). Random effects model OR was calculated for outcomes of interest including device-oriented composite events (DOCE; defined as composite of cardiac mortality, target vessel myocardial infarction (TV-MI), and ischaemia-driven target lesion revascularisation (TLR)), all-cause mortality, definite stent thrombosis, TV-MI and TLR...
January 23, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28108898/bioresorbable-scaffolds-for-coronary-artery-disease
#13
REVIEW
Ashwin Nathan, Taisei Kobayashi, Daniel M Kolansky, Robert L Wilensky, Jay Giri
PURPOSE OF REVIEW: The purpose of this review is to present an overview of the recent evidence regarding the use of bioresorbable scaffolds in percutaneous coronary intervention. RECENT FINDINGS: Bioresorbable scaffolds represent a potentially unique engineering solution to the problems associated with metallic stents. The Absorb everolimus-eluting bioresorbable scaffold has been the most extensively tested of this class and is currently Food and Drug Administration-approved for use in the USA...
January 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28105995/delayed-fracture-of-a-bioresorbable-vascular-scaffold-implanted-for-in-stent-restenosis
#14
Teresa Bastante, Javier Cuesta, Fernando Rivero, Marcos García-Guimaraes, Amparo Benedicto, Fernando Alfonso
No abstract text is available yet for this article.
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28102777/comparison-of-early-vascular-morphological-changes-between-bioresorbable-poly-l-lactic-acid-scaffolds-and-metallic-stents-in-porcine-iliac-arteries
#15
Yasuhito Sekimoto, Hideaki Obara, Kentaro Matsubara, Naoki Fujimura, Hirohisa Harada, Yuko Kitagawa
Bioresorbable scaffolds have the potential to overcome several problems associated with metallic stents. Bioresorbable poly-L-lactic acid (PLLA) scaffold implantation for the treatment of peripheral artery disease has already been reported in animal models and clinical trials; however, no studies comparing PLLA scaffolds and bare metal stents (BMSs) with regard to early vascular morphological changes, identified using intravascular ultrasound (IVUS) analysis, have been reported. In this study, PLLA scaffolds and BMSs were implanted bilaterally in iliac arteries of five miniature pigs...
January 19, 2017: Organogenesis
https://www.readbyqxmd.com/read/28096169/correction-to-procedural-and-long-term-outcomes-of-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions-the-bonito-registry-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions
#16
https://www.readbyqxmd.com/read/28089777/bioresorbable-vascular-scaffold-to-treat-malignant-in-stent-restenosis-in-a-patient-with-nickel-allergy
#17
Alfonso Jurado-Román, María T López-Lluva, Ignacio Sánchez-Pérez, Jesús Piqueras-Flores, Ramón Maseda, Fernando Lozano-Ruíz-Poveda
Nickel is the most frequent allergen in patients with allergic contact dermatitis and nickel allergy has been associated with recurrent in-stent restenosis. However, it is often misdiagnosed because of a low suspicion threshold. It should be discarded in patients with recurrent in-stent restenosis, especially if their medical history reveals prior contact dermatitis. It is also noteworthy and rarely specified that even newer generation stents that use novel metal alloys also contain low amounts of nickel. To avoid the implantation of new stents containing this metal, when percutaneous coronary intervention is indicated, drug eluting balloons or bioresorbable vascular scaffolds associated with small doses of steroids could provide good alternatives of treatment...
January 2, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28076449/long-term-follow-up-of-patients-after-percutaneous-coronary-intervention-with-everolimus-eluting-bioresorbable-vascular-scaffold
#18
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
January 9, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28069611/bioresorbable-vascular-scaffolds-for-the-treatment-of-chronic-total-occlusions-an-international-multicenter-registry
#19
Satoru Mitomo, Toru Naganuma, Yusuke Fujino, Hiroyoshi Kawamoto, Sandeep Basavarajaiah, Michael Pitt, Wei-Hsian Yin, Damras Tresukosol, Antonio Colombo, Sunao Nakamura
BACKGROUND: There are only limited studies reporting clinical outcomes after bioresorbable vascular scaffold (BVS; Absorb; Abbott Vascular, Santa Clara, CA) implantation for coronary chronic total occlusions (CTO). The aim of this study was to evaluate the real-world feasibility and safety of BVS implantation for the treatment of CTO. METHODS AND RESULTS: We retrospectively evaluated CTO cases treated with BVS from a multicenter registry. The primary end point was target lesion failure defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularization...
January 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28057285/very-late-bioresorbable-vascular-scaffold%C3%A2-thrombosis-smoke-or-fire
#20
EDITORIAL
Fernando Alfonso, Javier Cuesta
No abstract text is available yet for this article.
January 9, 2017: JACC. Cardiovascular Interventions
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