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Bioresorbable scaffolds

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https://www.readbyqxmd.com/read/29678390/bioresorbable-vascular-scaffolds-time-to-absorb-past-lessons-or-fade-away
#1
Aurélien de Pommereau, Quentin de Hemptinne, Olivier Varenne, Fabien Picard
No abstract text is available yet for this article.
April 17, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29672785/-tissue-engineering-of-adipose-tissue-with-biodegradable-biomaterials-for-soft-tissue-reconstruction
#2
Silvan Klein, Thiha Aung, Robert Michael Haas, Fabian Medved, Stefan M Schiller, Oliver Felthaus, Jürgen H Dolderer
Soft tissue defects resulting from injuries, tumor resection, congenital anomalies or chronic wounds pose a great challenge to reconstructive surgery. The current gold standard in therapy of such defects is the tissue transplantation in terms of free or local flaps. Unfortunately, donor site morbidity remains a considerable risk of flap surgery. Therefore, tissue engineering of autologous vascularized long term stable adipose tissue constructs could enrich the therapeutic possibilities of soft tissue defects...
April 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29668079/co-culture-of-adipose-derived-stem-cells-and-chondrocytes-on-three-dimensionally-printed-bioscaffolds-for-craniofacial-cartilage-engineering
#3
Robert J Morrison, Hassan B Nasser, Khaled N Kashlan, David A Zopf, Derek J Milner, Colleen L Flanangan, Matthew B Wheeler, Glenn E Green, Scott J Hollister
OBJECTIVES/HYPOTHESIS: Reconstruction of craniofacial cartilagenous defects are among the most challenging surgical procedures in facial plastic surgery. Bioengineered craniofacial cartilage holds immense potential to surpass current reconstructive options, but limitations to clinical translation exist. We endeavored to determine the viability of utilizing adipose-derived stem cell-chondrocyte co-culture and three-dimensional (3D) printing to produce 3D bioscaffolds for cartilage tissue engineering...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29667581/relation-between-bioresorbable-scaffold-sizing-using-qca-dmax-and-long-term-clinical-outcomes-in-1-232-patients-from-3-study-cohorts-absorb-cohort-b-absorb-extend-and-absorb-ii
#4
Yuki Katagiri, Yoshinobu Onuma, Taku Asano, Ply Chichareon, Carlos Collet, Yosuke Miyazaki, Jan J Piek, Joanna J Wykrzykowska, Alexandre Abizaid, John A Ormiston, Bernard Chevalier, Patrick W Serruys
AIMS: This study sought to investigate the long-term clinical outcomes related to scaffold sizing based on quantitative coronary angiography. METHODS AND RESULTS: A total of 1,248 patients who received Absorb bioresorbable scaffolds in the ABSORB Cohort B, ABSOR EXTEND, ABSORB II trials were included in the analysis. The incidence of MACE (a composite of cardiac death, any myocardial infarction [MI], and ischemia-driven target lesion revascularization [ID-TLR]) was analysed according to the Dmax subclassification of oversized scaffold group versus non-oversized (any undersize) scaffold group...
April 17, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29661987/review-of-the-latest-percutaneous-devices-in-critical-limb-ischemia
#5
REVIEW
Leila Haghighat, Sophia Elissa Altin, Robert R Attaran, Carlos Mena-Hurtado, Christopher J Regan
Critical limb ischemia (CLI) is a terminal stage of peripheral arterial disease that, in the absence of intervention, may lead to lower extremity amputation or death. Endovascular interventions have become a first-line approach to the management of CLI and have advanced considerably within the past decade. This review summarizes the types of percutaneous devices and the techniques that are available for the management of CLI and the data supporting their use. These include devices that establish and maintain vessel patency, including percutaneous transluminal angioplasty, drug-coated balloons, bare metal stents, drug-eluting stents, bioresorbable vascular scaffolds, and atherectomy; devices that provide protection from embolization; and, cell-based therapies...
April 14, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29656280/real-world-bioresorbable-vascular-scaffold-experience-compared-with-second-generation-metallic-drug-eluting-stents-in-complex-coronary-lesions
#6
Naotaka Okamoto, Hiroshi Ueda, Takahiro Yoshimura, Surbhi Chamaria, Samit Bhatheja, Yuliya Vengrenyuk, Samaneh Rabiei, Yonandy Barrientos, Vishal Kapur, Nitin Barman, Joseph Sweeny, Usman Baber, Roxana Mehran, Samin K Sharma, Annapoorna S Kini
OBJECTIVES: The aim of the study was to compare the acute outcomes of Absorb bioresorbable vascular scaffolds (BVS) and second-generation drug-eluting stent (DES) implantation in routine clinical practice. There is a paucity of data regarding BVS use in a real-world patient population. METHODS: The study population comprised 40 consecutive patients who underwent percutaneous coronary intervention (PCI) with BVS implantation at a tertiary-care center in New York, New York between July and December of 2016...
April 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29649071/predictors-of-early-scaffold-thrombosis-results-from-the-multicenter-prospective-german-austrian-absorb-registry
#7
Jochen Wöhrle, Holger M Nef, Christoph Naber, Stephan Achenbach, Thomas Riemer, Julinda Mehilli, Thomas Münzel, Steffen Schneider, Sinisa Markovic, Julia Seeger, Wolfgang Rottbauer, Thomas Pfannebecker, Gert Richardt, Ralf Zahn, Tommaso Gori, Johannes Kastner, Axel Schmermund, Christian W Hamm
BACKGROUND: In randomized clinical trials, the risk of thrombotic events with the absorb bioresorbable vascular scaffold (BVS) was significantly higher than with metallic drug-eluting stents. We evaluated predictors of scaffold thrombosis in the large-scale, multicenter German-Austrian ABSORB RegIstRy. METHODS AND RESULTS: 3178 patients with treatment of 4252 lesions using 5020 scaffolds were included. Follow-up rate at 6 months was 97.4%. Forty-five (1.42%) patients experienced definite/probable scaffold thrombosis during follow-up...
April 11, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29627111/in-stent-restenosis-of-drug-eluting-stents-compared-with-a-matched-group-of-patients-with-de-novo-coronary-artery-stenosis
#8
Kyle D Buchanan, Rebecca Torguson, Toby Rogers, Linzhi Xu, Jiaxiang Gai, Itsik Ben-Dor, William O Suddath, Lowell F Satler, Ron Waksman
Drug-eluting stents (DES) significantly reduced the incidence of in-stent restenosis (ISR). However, ISR still exists in the contemporary DES era. Previously deemed to be a benign process, ISR leads to complex presentation and intervention. This study aimed to compare the presentation and outcome of DES-ISR versus de novo lesions. We performed a retrospective analysis of 11,666 patients receiving percutaneous coronary intervention from 2003 to 2017 and divided them into 2 groups by de novo stenosis and ISR...
March 13, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29623171/bioresorbable-coronary-scaffolds-deployment-tips-and-tricks-and-the-future-of-the-technology
#9
REVIEW
J Ribamar Costa, Alexandre Abizaid
Bioresorbable scaffolds (BRS) were developed as an alternative to drug-eluting stents (DES) to facilitate vessel restoration and reduce the risk of future adverse events. However, recent meta-analyses and "real-world" registries have raised some concern about the safety of this novel technology, especially due to an increased risk of thrombosis within the first weeks of scaffold implantation. These devices appear to be less forgiving to poor implantation strategies when compared to contemporary DES...
January 2018: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29622143/bioresorbable-scaffold-for-treatment-of-coronary-artery-lesions-intravascular-ultrasound-results-from-the-absorb-japan-trial
#10
Kozo Okada, Yasuhiro Honda, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, M Brooke Hollak, Paul G Yock, Jeffrey J Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter J Fitzgerald, Takeshi Kimura
OBJECTIVES: The aim of this study was to characterize post-procedural intravascular ultrasound (IVUS) findings in the ABSORB Japan trial, specifically stratified by the size of target coronary arteries. BACKGROUND: Despite overall noninferiority confirmed in recent randomized trials comparing bioresorbable vascular scaffolds (BVS) (Absorb BVS) and cobalt-chromium everolimus-eluting metallic stents (CoCr-EES), higher event rates of Absorb BVS have been reported with suboptimal deployment, especially in small coronary arteries...
April 9, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29622142/bioresorbable-vascular-scaffolds-back-to-the-drawing-board
#11
EDITORIAL
Ehtisham Mahmud, Ryan R Reeves
No abstract text is available yet for this article.
April 9, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29622141/clinical-angiographic-and-procedural-correlates-of-very-late-absorb-scaffold-thrombosis-multistudy-registry-results
#12
Stephen G Ellis, Tommaso Gori, Patrick W Serruys, Holger Nef, Giuseppe Steffenino, Salvatore Brugaletta, Thomas Munzel, Cordula Feliz, Götz Schmidt, Manel Sabaté, Yoshinobu Onuma, R J van Geuns, Run-Lin Gao, Maurizio Menichelli, Dean J Kereiakes, Gregg W Stone, Luca Testa, Takeshi Kimura, Alexandre Abizaid
OBJECTIVES: The aim of this study was to identify independent correlates of very late scaffold thrombosis (VLST) from an analysis of consecutively treated patients from 15 multicenter studies. BACKGROUND: Recent analyses suggest an increased risk for VLST with the Absorb Bioresorbable Vascular Scaffold compared with drug-eluting stents, but insights as to correlates of risk are limited. METHODS: A total of 55 patients were identified with scaffold thrombosis...
April 9, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29576586/local-flow-patterns-after-implantation-of-bioresorbable-vascular-scaffold-in-coronary-bifurcations-novel-findings-by-computational-fluid-dynamics
#13
Yingguang Li, Zehang Li, Emil N Holck, Bo Xu, Antonios Karanasos, Zhenyu Fei, Yunxiao Chang, Miao Chu, Jouke Dijkstra, Evald H Christiansen, Johan H C Reiber, Niels R Holm, Shengxian Tu
BACKGROUND: Development of methods for accurate reconstruction of bioresorbable scaffolds (BRS) and assessing local hemodynamics is crucial for investigation of vascular healing after BRS implantation.Methods and Results:Patients with BRS that crossed over in a coronary bifurcation were included for analysis. Reconstructions of the coronary lumen and BRS were performed by fusion of optical coherence tomography and coronary angiography generating a tree model (TM) and a hybrid model with BRS (TM-BRS)...
March 24, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29564151/analysis-of-trends-and-prospects-regarding-stents-for-human-blood-vessels
#14
Jeong Hee Lee, Eung Do Kim, Eun Jung Jun, Hyoung Sun Yoo, Joon Woo Lee
Background: The purpose of this paper is to provide technology trends and information regarding market and prospects in stents used for human blood vessels in Korea and the world.A stent is a medical device in the form of a cylindrical metal net used to normalize flow when blood or other bodily fluids such as biliary fluids are obstructed in blood vessels, gastrointestinal tracts, etc. by inserting the stent into a narrowed or clogged area. Stents are classified into vascular and non-vascular stents...
2018: Biomaterials Research
https://www.readbyqxmd.com/read/29555614/time-for-a-debriefing-is-there-a-future-for-bioresorbable-scaffolds
#15
Davide Capodanno
No abstract text is available yet for this article.
March 20, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29550091/optical-coherence-tomographic-image-pattern-of-metallic-bioresorbable-vascular-scaffold-restenosis
#16
Jessica Roa-Garrido, Rosa M Cardenal-Piris, Ahmed Mahmoud El Amrawy, Antonio Gomez-Menchero, Santiago Camacho Freire, Jose Francisco Diaz-Fernandez
No abstract text is available yet for this article.
March 8, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29546748/bioresorbable-scaffolds-for-complex-coronary-interventions
#17
Maciej Lesiak, Sylwia Zawada-Iwańczyk, Magdalena Łanocha, Aneta Klotzka, Michał Lesiak
Bioresorbable scaffolds (BRS) have been introduced to clinical practice to avoid some limitations associated with the presence of permanent metal prostheses in coronary arteries. Due to elimination of the natural vasomotion of the vessel and flow disturbance, stents impair endothelial function, increasing the risk of adverse events such as late and very late thrombosis or accelerated neoatherosclerosis. Additionally, the presence of metallic stents hinders non-invasive imaging of coronaries and may exclude the possibility of bypass graft anastomosis within the stented segment...
March 15, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29537986/first-in-human-imaging-guided-bioresorbable-magnesium-scaffolds-in-acute-myocardial-infarction
#18
Fernando Alfonso, Marcos García-Guimaraes, Teresa Bastante, Esther González-Bartol, Javier Cuesta, Fernando Rivero
No abstract text is available yet for this article.
March 13, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29523976/correction-to-process-induced-degradation-of-bioresorbable-pdlga-in-bone-tissue-scaffold-production
#19
H Little, E Themistou, S A Clarke, E Cunningham, F Buchanan
The original version of this article unfortunately contained a mistake. E. Themistou was missing from the author group and so is now included with this erratum.
March 9, 2018: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29521477/serial-intravascular-ultrasound-evaluation-of-the-desolve%C3%A2-novolimus-eluting-bioresorbable-coronary-scaffold-system
#20
Gentil Barreira, J Ribamar Costa, Ricardo Costa, Rodolfo Staico, Daniel Chamie, Juliano R Slhessarenko, Luiz Fernando Tanajura, Andrea Abizaid, Amanda Sousa, Alexandre Abizaid
INTRODUCTION: Bioresorbable coronary scaffolds (BRS) have been developed to increase the late safety of coronary angioplasty by providing transitory coronary support and then being fully incorporated to the vessel wall. In the present trial, we sought to evaluate the performance and changes over time in the DESolve™ novolimus-eluting BRS using serial intravascular ultrasound (IVUS) in patients submitted to percutaneous coronary interventions. METHODS: Single-center, prospective, non-randomized study involving 17 consecutive patients submitted to implantation of the DESolve™ scaffold and serial evaluated with IVUS at different time points (post procedure, 6 and 18 months)...
March 9, 2018: Catheterization and Cardiovascular Interventions
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