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https://www.readbyqxmd.com/read/28637132/international-employee-perspectives-on-disability-management
#1
Shannon Wagner, Nicholas Buys, Ignatius Yu, Thomas Geisen, Henry Harder, Christine Randall, Alex Fraess-Phillips, Benedikt Hassler, Liz Scott, Karen Lo, Dan Tang, Caroline Howe
PURPOSE: To provide an international analysis of employees' views of the influence of disability management (DM) on the workplace. METHODOLOGY: An international research team with representation from Australia, Canada, China, and Switzerland collected survey data from employees in public and private companies in their respective regions. Due to lack of availability of current measures, a research team-created survey was used and a total of 1201 respondents were collected across the four countries...
February 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28636936/strong-tcr%C3%AE-%C3%AE-signaling-prohibits-thymic-development-of-il-17a-secreting-%C3%AE-%C3%AE-t-cells
#2
Nital Sumaria, Capucine L Grandjean, Bruno Silva-Santos, Daniel J Pennington
Despite a growing appreciation of γδ T cell contributions to numerous immune responses, the mechanisms that underpin their thymic development remain poorly understood. Here, using precursor/product relationships, we identify thymic stages in two distinct developmental pathways that generate γδ T cells pre-committed to subsequent secretion of either IL-17A or IFNγ. Importantly, this framework for tracking γδ T cell development has permitted definitive assessment of TCRγδ signal strength in commitment to γδ T cell effector fate; increased TCRγδ signal strength profoundly prohibited the development of all IL-17A-secreting γδ T cells, regardless of Vγ usage, but promoted the development of γδ progenitors along the IFNγ pathway...
June 20, 2017: Cell Reports
https://www.readbyqxmd.com/read/28632345/multiple-traumatic-experiences-post-traumatic-stress-disorder-and-offending-behaviour-in-female-prisoners
#3
Thanos Karatzias, Kevin Power, Caroline Woolston, Prathima Apurva, Amelie Begley, Carol Quinn, Sally Jowett, Ruth Howard, Allister Purdie
BACKGROUND: Although it is well established that prisoners commonly have histories of childhood trauma, little is known about mediators between exposure to trauma and criminal behaviour. HYPOTHESES: We hypothesised that the experience of trauma in adulthood, post-traumatic stress disorder (PTSD) and emotional dysregulation would mediate the relationship between childhood traumatic events and later criminal behaviour. METHODS: Eighty-nine female prisoners were interviewed using standardised scales, in a cross-sectional study design...
June 20, 2017: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/28632091/a-phenomenological-study-of-romantic-love-for-women-in-late-life
#4
Teresa J Moore, Joanni L Sailor
Romantic love in late life is often beneficial, though not without challenges. Financial concerns and objections of adult children can interfere with a late-life individual's decision to commit to a romantic relationship. In this study, the experience of romantic love for women who enter committed relationships in later life was examined. Fourteen women between the ages of 65 and 84 who had lived the experience of romantic love in late life were interviewed. By using Moustakas's qualitative Transcendental Phenomenological method, several themes emerged to provide a description of the phenomena...
March 3, 2017: Journal of Women & Aging
https://www.readbyqxmd.com/read/28628620/prevalence-and-determinants-of-online-sex-use-in-the-german-population
#5
Manfred E Beutel, Sebastian Giralt, Klaus Wölfling, Yve Stöbel-Richter, Claudia Subic-Wrana, Iris Reiner, Ana Nanette Tibubos, Elmar Brähler
INTRODUCTION: The unlimited access to sexual features in the World Wide Web has raised concerns about excessive and problematic online-sex use. However, little is known about antecedents of internet-sex use of different intensity. Based on a representative German sample of 2,522 participants between the ages of 14 and 97 years, the aims of the present study were (1) to determine the prevalence rates of online-sex users with the short version (ISSTGSV) of the Internet Sex Screening Test and (2) to associate online-sex use with anxious vs...
2017: PloS One
https://www.readbyqxmd.com/read/28623923/making-hiv-testing-work-at-the-point-of-care-in-south-africa-a-qualitative-study-of-diagnostic-practices
#6
Nora Engel, Malika Davids, Nadine Blankvoort, Keertan Dheda, Nitika Pant Pai, Madhukar Pai
BACKGROUND: Point of care testing promises to reduce delays in diagnosing and initiating treatment for infectious diseases such as Human Immuno-deficiency Virus (HIV). In South Africa, decentralized HIV testing with rapid tests offers important lessons for point of care testing programs. Yet, little is known about the strategies of providers and clients to make HIV testing successful in settings short of equipment, human resources and space. We aimed at examining these strategies. METHODS: This paper is based on a larger qualitative study of diagnostic practices across major diseases and actors in homes, clinics, communities, hospitals and laboratories in South Africa...
June 17, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28618034/computer-mediated-communication-in-intimate-relationships-associations-of-boundary-crossing-intrusion-relationship-satisfaction-and-partner-responsiveness
#7
Aaron M Norton, Joyce Baptist, Bernie Hogan
This study examined the impact of technology on couples in committed relationships through the lens of the couple and technology framework. Specifically, we used data from 6,756 European couples to examine associations between online boundary crossing, online intrusion, relationship satisfaction, and partner responsiveness. The results suggest that participants' reports of online boundary crossing were linked with lower relationship satisfaction and partner responsiveness. Also, lower relationship satisfaction and partner responsiveness were associated with increased online boundary crossing...
June 15, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28617971/risk-factors-that-influence-sexual-and-reproductive-health-in-portuguese-university-students
#8
M J Santos, E Ferreira, J Duarte, M Ferreira
BACKGROUND: University students have unprotected sex and associate alcohol and/or drugs with sexual practices. These behaviours are risk factors for influencing sexual and reproductive health that can be targeted by nursing interventions. AIM: The aim of this study was to determine the risk and protective factors influencing sexual and reproductive risk-taking behaviours in university students. METHODS: We conducted a cross-sectional and correlational study in a sample of 1946 students...
June 15, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28615927/p-tsa-promoted-syntheses-of-5h-benzo-h-thiazolo-2-3-b-quinazoline-and-indeno-1-2-d-thiazolo-3-2-a-pyrimidine-analogs-molecular-modeling-and-in-vitro-antitumor-activity-against-hepatocellular-carcinoma
#9
Amit K Keshari, Ashok K Singh, Vinit Raj, Amit Rai, Prakruti Trivedi, Balaram Ghosh, Umesh Kumar, Atul Rawat, Dinesh Kumar, Sudipta Saha
In our efforts to address the rising incidence of hepatocellular carcinoma (HCC), we have made a commitment to the synthesis of novel molecules to combat Hep-G2 cells. A facile and highly efficient one-pot, multicomponent reaction has been successfully devised utilizing a p-toluenesulfonic acid (p-TSA)-catalyzed domino Knoevenagel/Michael/intramolecular cyclization approach for the synthesis of novel 5H-benzo[h]thiazolo[2,3-b]quinazoline and indeno[1,2-d] thiazolo[3,2-a]pyrimidine analogs bearing a bridgehead nitrogen atom...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28610840/measuring-and-managing-health-system-performance-an-update-from-new-zealand
#10
Linda Maree Chalmers, Toni Ashton, Tim Tenbensel
In July 2016, New Zealand introduced a new approach to measuring and monitoring health system performance. This 'Systems Level Measure Framework' (SLMF) has evolved from the Integrated Performance and Incentive Framework (IPIF) previously reported in this journal. The SLMF is designed to stimulate a 'whole of system' approach that requires inter-organisational collaboration. Local 'Alliances' between government and non-government health sector organisations are responsible for planning and achieving improved health system outcomes such as reducing ambulatory sensitive hospitalisation for young children, and reducing acute hospital bed days...
June 2, 2017: Health Policy
https://www.readbyqxmd.com/read/28604315/exploitation-of-the-vulnerable-in-research-responses-to-lessons-learnt-in-history
#11
Amaboo Dhai
The Nuremberg Trials raised insightful issues on how and why doctors who were trained in the Hippocratic tradition were able to commit such egregious and heinous medical crimes. The vulnerable were considered to be subhuman, of decreased intelligence, of no moral status and lacking human dignity. The reputation of the medical profession had been undermined, professionalism questioned and the doctor-patient relationship damaged as a result of the Nazi medical experiments. The World Medical Association's Declaration of Helsinki has been hailed as one of the most successful efforts in rescuing medical research from the darkness of the scandals and tragedies in health research...
May 24, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28599768/exposure-to-science-perspectives-on-science-and-religion-and-religious-commitment-in-young-adulthood
#12
Jeremy E Uecker, Kyle C Longest
Social scientists know very little about the consequences of exposure to scientific knowledge and holding different perspectives on science and religion for individuals' religious lives. Drawing on secularization and post-secular theories, we develop and test several hypotheses about the relationships among exposure to scientific knowledge, perspectives on religion and science, and religious commitment using panel data from the National Study of Youth and Religion. Our findings indicate that religious faith is strongest among young adults who: (1) accommodate scientific knowledge into their religious perspective, or (2) reject scientific knowledge that directly contradicts their religious beliefs about the origins of the world...
July 2017: Social Science Research
https://www.readbyqxmd.com/read/28599713/working-memory-over-a-six-year-period-in-young-binge-drinkers
#13
C Carbia, F Cadaveira, E López-Caneda, F Caamaño-Isorna, S Rodríguez Holguín, M Corral
Adolescence and early adulthood are periods of particular vulnerability to the neurotoxic effects of alcohol. Young people with alcohol-use disorders display deficits in working memory (WM). This function is supported by the prefrontal cortex, a late-maturing brain region. However, little is known about the progression of cognitive dysfunctions associated with a binge-drinking (BD) pattern of alcohol consumption among non-clinical adolescents. The objective of this study was to analyze the relationship between BD trajectory and WM in university students...
June 2017: Alcohol
https://www.readbyqxmd.com/read/28598385/the-roles-of-long-non-protein-coding-rnas-in-osteo-adipogenic-lineage-commitment
#14
REVIEW
Hirotaka Yoshioka, Yuji Yoshiko
Osteoblasts and adipocytes share a common mesenchymal progenitor in the bone marrow. This implies that a reciprocal relationship exists between osteogenic and adipogenic differentiation. Further, cells of osteoblast lineage transdifferentiate into adipocytes under some circumstances. Dysregulation of osteo-adipogenic fate-determination leads to bone diseases such as osteoporosis, accompanied by an increase in bone marrow adipose tissue. Thus, the fine-tuning of osteo-adipogenesis is necessary for bone homeostasis...
June 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28597940/-undoing-or-symbolic-reversal-at-homicide-crime-scenes
#15
Maria Russell, Louis B Schlesinger, Maria Leon, Samantha Holdren
A closed case file review of a nonrandom national sample of 975 homicides disclosed 11 cases (1.13%) of undoing, wherein offenders engaged in crime scene behavior that has been considered an attempt to symbolically reverse the murder. The frequency of the various methods of undoing involved the use of blankets to cover the victim's body (55%), positioning the body (55%), use of a bed or couch (42%), washing the body (36%), using pillows (36%), as well as removing clothing and adding other types of adornments (27%)...
June 9, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28596084/stem-cell-evolutionary-paradigm-and-cell-engineering
#16
Z Ivanovic
Studying hematopoietic and mesenchymal stem cells for almost three decades revealed some similarities between the stem cell entity and the single-celled eukaryotes exhibiting the anaerobic/facultative aerobic metabolic features. A careful analysis of nowadays knowledge concerning the early eukaryotic evolution allowed us to reveal some analogies between stem cells in the metazoan tissues and the single-celled eukaryotes which existed during the first phase of eukaryotes evolution in mid-Proterozoic era. In fact, it is possible to trace the principle of the self-renewal back to the first eukaryotic common ancestor, the first undifferentiated nucleated cell possessing the primitive, mostly anaerobically-respiring mitochondria and a capacity to reproduction by a simple cell division "à l'identique"...
June 5, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28592283/health-systems-research-in-fragile-and-conflict-affected-states-a-qualitative-study-of-associated-challenges
#17
Tim Martineau, Aniek Woodward, Kate Sheahan, Egbert Sondorp
BACKGROUND: High quality health systems research (HSR) in fragile and conflict-affected states (FCAS) is essential to guiding the policies and programmes that will improve access to health services and, ultimately, health outcomes. Yet, conducting HSR in FCAS is challenging. An understanding of these challenges is essential to tackling them and to supporting research conducted in these complex environments. Led by the Thematic Working Group on Health Systems in FCAS, the primary aim of this study was to develop a research agenda on HSR in FCAS...
June 7, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28590387/the-2016-american-orthopaedic-association-japanese-orthopaedic-association-traveling-fellowship
#18
Sumon Nandi, Samuel K Cho, Brett A Freedman, Reza Firoozabadi
The American Orthopaedic Association-Japanese Orthopaedic Association (AOA-JOA) Traveling Fellowship, which began in 1992 as a collaborative effort between the 2 orthopaedic communities, is aimed at fostering leadership among early-career surgeons through clinical, academic, and cultural exchange. Over 3 weeks, we experienced an extraordinary journey that led us across nearly 800 miles of the picturesque Japanese countryside, with stops at 6 distinguished academic centers. The opportunity to become personally acquainted with orthopaedic leaders in Japan, learn from their experiences, and immerse ourselves in the ancient and storied culture of a beautiful country was one that we will not soon forget...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28588529/program-to-promote-personal-and-social-responsibility-in-the-secondary-classroom
#19
Miguel A Carbonero, Luis J Martín-Antón, Lourdes Otero, Eugenio Monsalvo
The performance of school children has been studied by considering partial relationships between several personal variables such as the link between cognition and motivation. However, contextual variables, such as a child's willingness to accept social responsibility, also influence students' social and academic performance. Thus, students with greater responsibility have a better attitude toward their studies, resulting in higher academic achievement. This 2-year study aims to reveal to what extent an intervention program affects student performance and is based on the Theory of Positive Action among young people proposed by Don Hellison and the Theory of Reasoned Action by Fishbein and Ajzen...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28585288/incentives-for-preventing-smoking-in-children-and-adolescents
#20
REVIEW
Marita Hefler, Selma C Liberato, David P Thomas
BACKGROUND: Adult smoking usually has its roots in adolescence. If individuals do not take up smoking during this period it is unlikely that they ever will. Further, once smoking becomes established, cessation is challenging; the probability of subsequently quitting is inversely proportional to the age of initiation. One novel approach to reducing the prevalence of youth smoking is the use of incentives. OBJECTIVES: To assess the effect of incentives on preventing children and adolescents (aged 5 to 18 years) from starting to smoke...
June 6, 2017: Cochrane Database of Systematic Reviews
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