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https://www.readbyqxmd.com/read/28110111/applying-a-novel-statistical-method-to-advance-the-personalized-treatment-of-anxiety-disorders-a-composite-moderator-of-comparative-drop-out-from-cbt-and-act
#1
Andrea N Niles, Kate B Wolitzky-Taylor, Joanna J Arch, Michelle G Craske
BACKGROUND: No prior studies have examined moderators of dropout between distinct treatments for anxiety disorders. This study applied a novel statistical approach for examining moderators of dropout from traditional cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT). METHOD: We combined data from two randomized controlled trials (N = 208) comparing CBT and ACT for patients with DSM-IV anxiety disorders. Adapting Kraemer's method for constructing and evaluating composite moderators (2013), 26 variables were examined for individual effect sizes...
January 4, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28109882/is-the-absence-or-intermittent-yf-vaccination-the-major-contributor-to-its-persistent-outbreaks-in-eastern-africa
#2
Marycelin Mandu Baba, Ikusemoran Mayomi
The Europe 2020 strategy and recently ratified Paris agreement are the main documents in the European Union (EU) involving energy and climate policy. Therefore, the aim of this paper is to reveal the possibilities of EU countries to achieve the Europe 2020 strategy and Paris agreement targets. Referring to the regression analysis, the results showed that the growth of economy and primary energy consumption stimulate GHG emissions in EU-28; meanwhile, the increase of RES share decreased them. Moreover, the paper revealed that if the EU will achieve its targets committed in the Europe 2020 strategy, even assuming fast economic growth, the target to reduce GHG emission by 20% by 2020 compared to 1990 will be achieved...
January 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28109706/cost-effectiveness-of-13-valent-pneumococcal-conjugate-vaccination-in-mongolia
#3
Neisha Sundaram, Cynthia Chen, Joanne Yoong, Munkh-Erdene Luvsan, Kimberley Fox, Amarzaya Sarankhuu, Sophie La Vincente, Mark Jit
OBJECTIVE: The Ministry of Health (MOH), Mongolia, is considering introducing 13-valent pneumococcal conjugate vaccine (PCV13) in its national immunization programme to prevent the burden of disease caused by Streptococcus pneumoniae. This study evaluates the cost-effectiveness and budget impact of introducing PCV13 compared to no PCV vaccination in Mongolia. METHODS: The incremental cost-effectiveness ratio (ICER) of introducing PCV13 compared to no PCV vaccination was assessed using an age-stratified static multiple cohort model...
January 18, 2017: Vaccine
https://www.readbyqxmd.com/read/28109613/the-1951-harvard-student-uprising-against-the-intern-match
#4
Don K Nakayama, W Hardy Hendren
In the fall of 1951, a group of Harvard medical students led by W. Hardy Hendren, III organized a national movement against the newly instituted match that would assign graduating seniors to hospital internship programs. Before then, hospitals with intern positions to fill rushed to secure commitments from students, who in turn accepted the first decent offer that came their way. Knowing that students could not risk waiting for a better offer, hospitals pushed them into making early commitments. When some students began getting offers in their junior and sophomore years, medical schools, professional groups, and hospitals organized the National Inter-association Committee on Internships to deal with the issue...
January 18, 2017: Surgery
https://www.readbyqxmd.com/read/28109193/open-science-at-an-institutional-level-an-interview-with-guy-rouleau
#5
Guy Rouleau
The director of the Montreal Neurological Institute (MNI), Guy Rouleau, discusses the recent announcement that the MNI will be completely committed to open science.
January 20, 2017: Genome Biology
https://www.readbyqxmd.com/read/28108952/transcriptional-regulators-dictate-innate-lymphoid-cell-fates
#6
REVIEW
Chao Zhong, Jinfang Zhu
Research on innate lymphoid cells (ILC) has recently been a fast paced topic of immunological research. As ILCs are able to produce signature Th cytokine, ILCs have garnered considerable attention and have been described to represent the innate counterpart of the CD4(+) T helper (Th) cells. The development and function of ILCs are precisely regulated by a network of crucial transcription factors, which are also involved in the development or differentiation of conventional natural killer (cNK) cells and T cells...
January 20, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28108728/balancing-parenthood-and-practice
#7
Carolyne Crowe
Women now account for 76 per cent of new veterinary undergraduate intakes and feminisation of the profession has long been a topic for discussion and debate. Many vets want greater commitment to family life and better work-life balance. Carolyne Crowe outlines some new information and online support that's available for all veterinary professionals.
January 21, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28108485/tgf-%C3%AE-family-signaling-in-embryonic-and-somatic-stem-cell-renewal-and-differentiation
#8
Alan C Mullen, Jeffrey L Wrana
Soon after the discovery of transforming growth factor-β (TGF-β), seminal work in vertebrate and invertebrate models revealed the TGF-β family to be central regulators of tissue morphogenesis. Members of the TGF-β family direct some of the earliest cell-fate decisions in animal development, coordinate complex organogenesis, and contribute to tissue homeostasis in the adult. Here, we focus on the role of the TGF-β family in mammalian stem-cell biology and discuss its wide and varied activities both in the regulation of pluripotency and in cell-fate commitment...
January 20, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28107513/the-zebrafish-anillin-egfp-reporter-marks-late-dividing-retinal-precursors-and-stem-cells-entering-neuronal-lineages
#9
Meret Cepero Malo, Anne-Laure Duchemin, Luca Guglielmi, Eva Patzel, Saadettin Sel, Gerd U Auffarth, Matthias Carl, Lucia Poggi
Monitoring cycling behaviours of stem and somatic cells in the living animal is a powerful tool to better understand tissue development and homeostasis. The tg(anillin:anillin-eGFP) transgenic line carries the full-length zebrafish F-actin binding protein Anillin fused to eGFP from a bacterial artificial chromosome (BAC) containing Anillin cis-regulatory sequences. Here we report the suitability of the Anillin-eGFP reporter as a direct indicator of cycling cells in the late embryonic and post-embryonic retina...
2017: PloS One
https://www.readbyqxmd.com/read/28107293/the-age-of-value-navigating-the-transition-from-volume-to-value
#10
Renée M Glanzman
The healthcare industry has historically rewarded providers on the basis of the volume of services rendered, rather than the value of those services. Through the commitment of the Department of Health and Human Services, new programs and legislation have been created to tie provider payment based on the achievement of the Triple Aim: improve the patient experience, reduce cost, and improve overall health. As a result, new programs and legislation have emerged, resulting in the need for cultural shifts, new skills, and new technology for health systems, providers, and patients...
January 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28107103/why-do-we-hate-hypocrites-evidence-for-a-theory-of-false-signaling
#11
Jillian J Jordan, Roseanna Sommers, Paul Bloom, David G Rand
Why do people judge hypocrites, who condemn immoral behaviors that they in fact engage in, so negatively? We propose that hypocrites are disliked because their condemnation sends a false signal about their personal conduct, deceptively suggesting that they behave morally. We show that verbal condemnation signals moral goodness (Study 1) and does so even more convincingly than directly stating that one behaves morally (Study 2). We then demonstrate that people judge hypocrites negatively-even more negatively than people who directly make false statements about their morality (Study 3)...
January 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28106682/creating-a-culture-of-success-using-the-magnet-recognition-program%C3%A2-as-a-framework-to-engage-nurses-in-an-australian-healthcare-facility
#12
Sandra Moss, Marion Mitchell, Veronica Casey
An organizational culture that reflects distrust, fear of reprisal, reluctance to challenge the status quo, acceptance of poor practice, denial, and lack of accountability creates significant issues in healthcare in relation to employee retention, burnout, organizational commitment, and patient safety. Changing culture is one of the most challenging endeavors an organization will encounter. We highlight that the Magnet Recognition Program® can be implemented as an organizational intervention to positively impact on nursing workplace culture in an international healthcare facility...
February 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28105876/what-drives-continuous-improvement-project-success-in-healthcare
#13
Paul Stelson, Joshua Hille, Chinweike Eseonu, Toni Doolen
Purpose The purpose of this paper is to present findings from a study of factors that affect continuous improvement (CI) project success in hospitals. Design/methodology/approach Quantitative regression analysis was performed on Likert scale survey responses. Qualitative thematic analysis was performed on open-ended survey responses and written reports on CI projects. Findings The paper identifies managerial and employee factors that affect project success. These factors include managerial support, communication, and affective commitment...
February 13, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28105676/dahl-j-stewart-i-martell-c-kaplan-j-s-2014-act-rft-in-relationships-helping-clients-deepen-intimacy-and-maintain-healthy-commitments-using-acceptance-and-commitment-therapy-and-relational-frame-theory-oakland-ca-new-harbinger-278-pp-58-95
#14
REVIEW
https://www.readbyqxmd.com/read/28105494/suicide-with-two-makes-of-captive-bolt-guns-livestock-stunners-fired-simultaneously-to-the-forehead
#15
Rebecca Pircher, Dorothee Geisenberger, Markus Große Perdekamp, Merja Neukamm, Stefan Pollak, Ulrike Schmidt, Annette Thierauf-Emberger
In humans, most fatalities from slaughterer's guns are suicides committed by persons familiar with stunning devices. The great majority of cases accounts for shots to the head, especially the frontal region. Only a small number of two subsequent cranial shots from captive-bolt humane killers have been reported up to now. In the case presented by the authors, a suicide by simultaneous shots to the head fired from two different makes of captive-bolt guns (one of them having two separate outlets for the combustion gases in the muzzle plane, the other type having no additional openings) is described for the first time...
January 20, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28104892/mechanistic-basis-for-a-molecular-triage-reaction
#16
Sichen Shao, Monica C Rodrigo-Brenni, Maryann H Kivlen, Ramanujan S Hegde
Newly synthesized proteins are triaged between biosynthesis and degradation to maintain cellular homeostasis, but the decision-making mechanisms are unclear. We reconstituted the core reactions for membrane targeting and ubiquitination of nascent tail-anchored membrane proteins to understand how their fate is determined. The central six-component triage system is divided into an uncommitted client-SGTA complex, a self-sufficient targeting module, and an embedded but self-sufficient quality control module. Client-SGTA engagement of the targeting module induces rapid, private, and committed client transfer to TRC40 for successful biosynthesis...
January 20, 2017: Science
https://www.readbyqxmd.com/read/28104765/raffaella-lombardi-steadfast-and-committed
#17
Ruth Williams
No abstract text is available yet for this article.
January 20, 2017: Circulation Research
https://www.readbyqxmd.com/read/28104716/source-3-registry-design-and-30-day-results-of-the-european-post-approval-registry-of-the-latest-generation-of-the-sapien-3tm-transcatheter-heart-valve
#18
Olaf Wendler, Gerhard Schymik, Hendrik Treede, Helmut Baumgartner, Nicolas Dumonteil, Leo Ihlberg, Franz-Josef Neumann, Giuseppe Tarantini, José L Zamorano, Alec Vahanian
BACKGROUND: -The SOURCE 3 Registry is a European multicentre, observational registry of the latest generation of transcatheter heart valve, the SAPIEN 3(TM) (Edwards Lifesciences, Irvine, CA/USA). Its purpose is to document outcomes of clinical safety and performance after European approval was given. METHODS: -In this manuscript we present the 30-day outcome of the SOURCE 3 Registry. All data is self-reported and all participating centres have committed to support their consecutive experience with the SAPIEN 3(TM) transcatheter heart valve, dependent on patients consent, before the start of the study...
January 19, 2017: Circulation
https://www.readbyqxmd.com/read/28104697/male-birthweight-semen-quality-and-birth-outcomes
#19
B W Whitcomb, M S Bloom, S Kim, Z Chen, G M Buck Louis
STUDY QUESTION: What are the relations among birthweight (BW), semen parameters and birth outcomes in a population-based sample? SUMMARY ANSWER: BW is unrelated to semen parameters, which are in turn unrelated to birth outcomes. WHAT IS KNOWN ALREADY: In clinical settings, there has been suggestion that semen parameters are related to BW when comparing fertile and infertile men; however, findings have been less clear in more general populations...
January 18, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28104571/non-violent-threats-and-promises-among-closed-market-drug-dealers
#20
Timothy Dickinson
BACKGROUND: An unintended consequence of drug prohibitions is that they often fail to absolutely deter potential drug dealers and users and instead restrictively deter them. One way in which dealers sometimes alter their behaviour in response to these prohibitions is by using violent forms of social control to prevent their customers from committing careless behaviour or from becoming police informants. Many dealers, however, are reluctant to use violent forms of social control for various reasons...
January 16, 2017: International Journal on Drug Policy
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