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https://www.readbyqxmd.com/read/28227900/automated-assessment-of-postural-stability-system
#1
Alessandro Napoli, Christian R Ward, Stephen M Glassd, Carole Tucker, Iyad Obeid, Alessandro Napoli, Christian R Ward, Stephen M Glass, Carole Tucker, Iyad Obeid, Christian R Ward, Carole Tucker, Alessandro Napoli, Iyad Obeid, Stephen M Glass
The Balance Error Scoring System (BESS) is one of the most commonly used clinical tests to evaluate static postural stability deficits resulting from traumatic brain events and musculoskeletal injury. This test requires a trained operator to visually assess balance and give the subject a performance score based on the number of balance "errors" they committed. Despite being regularly used in several real-world situations, the BESS test is scored by clinician observation and is therefore (a) potentially susceptible to biased and inaccurate test scores and (b) cannot be administered in the absence of a trained provider...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226301/the-influence-of-welfare-systems-on-pay-for-performance-programs-for-general-practitioners-a-critical-review
#2
REVIEW
Mehdi Ammi, Grant Fortier
While pay-for-performance (P4P) programs are increasingly common tools used to foster quality and efficiency in primary care, the evidence concerning their effectiveness is at best mixed. In this article, we explore the influence of welfare systems on four P4P-related dimensions: the level of healthcare funders' commitment to P4Ps (by funding and length of program operation), program design (specifically target-based vs. participation-based program), physicians' acceptance of the program and program effects...
February 16, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28226240/position-and-hippo-signaling-dependent-plasticityduring-lineage-segregation-in-the-early-mouse-embryo
#3
Eszter Posfai, Sophie Petropoulos, Flavia Ro de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant
The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the overall relationship between cell commitment and global gene expression changes are still unclear. Single-cell RNA sequencing during lineage segregation revealed that the TE transcriptional profile stabilizes earlier than the ICM and prior to blastocyst formation...
February 22, 2017: ELife
https://www.readbyqxmd.com/read/28226053/social-representations-of-fishermen-with-spinal-cord-injury-impacts-and-life-trajectory
#4
Eliane Santos Cavalcante, João Mário Pessoa, Izaura Luzia Silvério Freire, Cleonice Andréa Alves Cavalcante, Francisco Arnoldo Nunes de Miranda
Objective: analyze social representations in the life trajectory of artisanal fishermen with spinal cord injury caused by diving on the north coast of Rio Grande do Norte. Method: a descriptive, qualitative study was conducted with 31 fishermen between October 2013 and August 2014, using a semi-structured interview. A lexicographic analysis and descending hierarchical classification of texts were performed (with software ALCESTE), in the perspective of the social representations...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28225908/intimate-partner-violence-reported-by-female-and-male-users-of-healthcare-units
#5
Claudia Renata Dos Santos Barros, Lilia Blima Schraiber
OBJECTIVE: To analyze nonfatal violence suffered and committed by adult men and women, in an intimate relationship. METHODS: The participants in the research were women aged between 15 and 49 years and men between 18 and 60 years, interviewed by face-to-face questionnaire application. The sample selection was of consecutive type, according to the order of arrival of the users. We conducted temporarily independent investigations and covered different health services to avoid couples and relationships in which the retaliation could be overvalued...
February 16, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28225545/enhancing-political-will-for-universal-health-coverage-in-nigeria
#6
Bolaji S Aregbeshola
Universal health coverage aims to increase equity in access to quality health care services and to reduce financial risk due to health care costs. It is a key component of international health agenda and has been a subject of worldwide debate. Despite differing views on its scope and pathways to reach it, there is a global consensus that all countries should work toward universal health coverage. The goal remains distant for many African countries, including Nigeria. This is mostly due to lack of political will and commitment among political actors and policymakers...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28224872/-lessons-learned-from-the-evacuation-of-the-vu-university-medical-centre-after-flooding
#7
T H Biesheuvel, C Brouwers, F W Bloemers
On 8 September 2015, flooding of the lower floors of the VU University Medical Center in Amsterdam caused serious damage to many vital technical services, such as water and power supplies. The decision was made to completely evacuate the university hospital. This paper describes the chronology and events of that day and shares a number of important lessons that were learned, in order to help readers to optimise crisis organisation in their own institutions. A serious situation or disaster can never be standardised in protocols or manuals; flexibility, improvisation and confidence in one another's expertise and commitment are therefore essential...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28224828/with-strings-attached
#8
James Buchan
At the end of last year, it was announced that bursaries will continue to be available to new nursing students in Wales in 2017-18, but with a sting in the tail. Under the proposals, nurses who train in Wales will be required to spend the first two years of their careers in the country. This follows the suggestion that doctors trained in England will have to 'give back' four years of service after qualifying, or buy themselves out of this commitment.
February 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28224719/cardiomyocyte-differentiation-promotes-cell-survival-during-nicotinamide-phosphoribosyltransferase-inhibition-through-increased-maintenance-of-cellular-energy-stores
#9
Erin M Kropp, Katarzyna A Broniowska, Matthew Waas, Alyssa Nycz, John A Corbett, Rebekah L Gundry
To address concerns regarding the tumorigenic potential of undifferentiated human pluripotent stem cells (hPSC) that may remain after in vitro differentiation and ultimately limit the broad use of hPSC-derivatives for therapeutics, we recently described a method to selectively eliminate tumorigenic hPSC from their progeny by inhibiting nicotinamide phosphoribosyltransferase (NAMPT). Limited exposure to NAMPT inhibitors selectively removes hPSC from hPSC-derived cardiomyocytes (hPSC-CM) and spares a wide range of differentiated cell types; yet, it remains unclear when and how cells acquire resistance to NAMPT inhibition during differentiation...
February 22, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28223921/epigenetic-modulation-of-stem-cells-in-neurodevelopment-the-role-of-methylation-and-acetylation
#10
REVIEW
Martyna Podobinska, Ilona Szablowska-Gadomska, Justyna Augustyniak, Ioanna Sandvig, Axel Sandvig, Leonora Buzanska
The coordinated development of the nervous system requires fidelity in the expression of specific genes determining the different neural cell phenotypes. Stem cell fate decisions during neurodevelopment are strictly correlated with their epigenetic status. The epigenetic regulatory processes, such as DNA methylation and histone modifications discussed in this review article, may impact both neural stem cell (NSC) self-renewal and differentiation and thus play an important role in neurodevelopment. At the same time, stem cell decisions regarding fate commitment and differentiation are highly dependent on the temporospatial expression of specific genes contingent on the developmental stage of the nervous system...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28223401/transcriptome-analyses-of-rhesus-monkey-pre-implantation-embryos-reveal-a-reduced-capacity-for-dna-double-strand-break-repair-in-primate-oocytes-and-early-embryos
#11
Xinyi Wang, Denghui Liu, Dajian He, Shengbo Suo, Xian Xia, Xiechao He, Jing-Dong Han, Ping Zheng
Pre-implantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell fate commitment, most of which remain mechanistically unclear in primates. In addition, primates display a high rate of embryo wastage without any clear molecular basis. Understanding the factors involved in genome reprogramming and ZGA will help the generation of induced pluripotent stem cells with high efficiency. Moreover, explaining the molecular basis responsible for embryo wastage in primates will greatly expand our knowledge of species evolution...
February 21, 2017: Genome Research
https://www.readbyqxmd.com/read/28223286/royal-college-welcomes-government-s-commitment-to-eu-workers
#12
Abi Rimmer
No abstract text is available yet for this article.
February 21, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28223284/mafa-enables-pdx1-to-effectively-convert-pancreatic-islet-progenitors-and-committed-islet-%C3%AE-cells-into-%C3%AE-cells-in-vivo
#13
Taka-Aki Matsuoka, Satoshi Kawashima, Takeshi Miyatsuka, Shugo Sasaki, Naoki Shimo, Naoto Katakami, Dan Kawamori, Satomi Takebe, Pedro L Herrera, Hideaki Kaneto, Roland Stein, Iichiro Shimomura
Among the therapeutic avenues being explored for replacement of the functional islet β-cell mass lost in Type 1 diabetes (T1D), reprogramming of adult cell types into new β-cells has been actively pursued. Notably, mouse islet α-cells will transdifferentiate into β-cells under conditions of near β-cell loss, a condition similar to T1D. Moreover, human islet α-cells also appear to poised for reprogramming into insulin(+) cells. Here we have generated transgenic mice conditionally expressing the islet β-cell-enriched Mafa and/or Pdx1 transcription factors to examine their potential to transdifferentiate embryonic pan-islet cell Ngn3(+) progenitors and the later glucagon(+) α-cell population into β-cells...
February 21, 2017: Diabetes
https://www.readbyqxmd.com/read/28223074/recent-advances-in-biomedical-applications-of-fluorescent-gold-nanoclusters
#14
REVIEW
Youkun Zheng, Lanmei Lai, Weiwei Liu, Hui Jiang, Xuemei Wang
Fluorescent gold nanoclusters (AuNCs) are emerging as novel fluorescent materials and have attracted more and more attention in the field of biolabeling, biosensing, bioimaging and targeted cancer treatment because of their unusual physicochemical properties, such as long fluorescence lifetime, ultrasmall size, large Stokes shift, strong photoluminescence, as well as excellent biocompatibility and photostability. Recently, significant efforts have been committed to the preparation, functionalization and biomedical application studies of fluorescent AuNCs...
February 16, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28222974/primary-health-care-attributes-and-responses-to-intimate-partner-violence-in-spain
#15
Isabel Goicolea, Paola Mosquera, Erica Briones-Vozmediano, Laura Otero-García, Marta García-Quinto, Carmen Vives-Cases
OBJECTIVE: This study provides an overview of the perceptions of primary care professionals on how the current primary health care (PHC) attributes in Spain could influence health-related responses to intimate partner violence (IPV). METHODS: A qualitative study was conducted using semi-structured interviews with 160 health professionals working in 16 PHC centres in Spain. Data were analysed using a qualitative content analysis. RESULTS: Four categories emerged from the interview analysis: those committed to the PHC approach, but with difficulties implementing it; community work relying on voluntarism; multidisciplinary team work or professionals who work together?; and continuity of care hindered by heavy work load...
February 18, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28222728/looking-forward-to-the-next-15-years-innovation-and-new-pathways-for-research-in-health-equity
#16
EDITORIAL
Ana Lorena Ruano, Efrat Shadmi, John Furler, Krishna Rao, Miguel San Sebastián, Manuela Villar Uribe, Leiyu Shi
Since our launch in 2002, the International Journal for Equity in Health (IJEqH) has furthered our collective understanding of equity in health and health services by providing a platform on which academics and practitioners can share their work. Today, we celebrate our fifteenth anniversary with an article collection that presents a call for new and novel research in equity in health and we invite our authors to use new approaches and methods, and to focus on emerging areas of research related to health equity in order to set the stage for the next fifteen years of health equity research...
February 21, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28222084/african-american-women-s-recollected-experiences-of-adherence-to-breast-cancer-treatment
#17
Sue P Heiney, DeAnne K Hilfinger Messias, Tisha M Felder, Kenneth W Phelps, Jada C Quinn
PURPOSE/OBJECTIVES: To explore African American women's recollected experiences of breast cancer treatment.
. RESEARCH APPROACH: Qualitative description and narrative analysis.
. SETTING: South Carolina Oncology Associates, an outpatient oncology clinic serving rural and urban populations.
. PARTICIPANTS: 16 African American women with breast cancer previously enrolled in the control arm (n = 93) of a completed randomized, controlled trial...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28220722/life-after-research-misconduct
#18
Kyle L Galbraith
Research misconduct is a serious violation of a scientific community's ethical standards. Scientists who commit research misconduct typically face corrective actions from employers and funding agencies, as well as significant professional stigma. Unfortunately, there is little systematic data about the post-misconduct career of these guilty parties. Through a review of Office of Research Integrity (ORI) case summaries, I identified a pool of 284 researchers who engaged in research misconduct and were subject to ORI corrective actions...
February 2017: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/28220515/challenges-in-conducting-multicentre-multidisciplinary-longitudinal-studies-in-children-with-chronic-conditions
#19
Hillary L Broder, Canice E Crerand, Ryan R Ruff, Alexandre Peshansky, David B Sarwer, Lacey Sischo
OBJECTIVES: Conducting longitudinal, multicentre, multidisciplinary research for individuals with chronic conditions can be challenging. Despite careful planning, investigative teams must adapt to foreseen and unforeseen problems. Our objective is to identify challenges encountered and solutions sought in a recently completed observational, longitudinal study of youth with cleft lip and palate as well as their caregivers. METHODS: Data for analysis were derived from a 6-year, multicentre, prospective, longitudinal study of youth with cleft conducted from 2009 to 2015 that examined oral health-related quality of life and other related clinical observations over time in youth who had cleft-related surgery compared to those who did not...
February 21, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28220091/effort-in-multitasking-local-and-global-assessment-of-effort
#20
Andrea Kiesel, David Dignath
When performing multiple tasks in succession, self-organization of task order might be superior compared to external-controlled task schedules, because self-organization allows optimizing processing modes and thus reduces switch costs, and it increases commitment to task goals. However, self-organization is an additional executive control process that is not required if task order is externally specified and as such it is considered as time-consuming and effortful. To compare self-organized and externally controlled task scheduling, we suggest assessing global subjective and objectives measures of effort in addition to local performance measures...
2017: Frontiers in Psychology
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