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https://www.readbyqxmd.com/read/28534875/dose-dependent-social-cognitive-effects-of-intranasal-oxytocin-delivered-with-novel-breath-powered-device-in-adults-with-autism-spectrum-disorder-a-randomized-placebo-controlled-double-blind-crossover-trial
#1
D S Quintana, L T Westlye, S Hope, T Nærland, T Elvsåshagen, E Dørum, Ø Rustan, M Valstad, L Rezvaya, H Lishaugen, E Stensønes, S Yaqub, K T Smerud, R A Mahmoud, P G Djupesland, O A Andreassen
The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism spectrum disorders (ASD). However, clinical research progress has been hampered by a poor understanding of oxytocin's dose-response and sub-optimal intranasal delivery methods. We examined two doses of oxytocin delivered using a novel Breath Powered intranasal delivery device designed to improve direct nose-to-brain activity in a double-blind, crossover, randomized, placebo-controlled trial. In a randomized sequence of single-dose sessions, 17 male adults with ASD received 8 international units (IU) oxytocin, 24IU oxytocin or placebo followed by four social-cognitive tasks...
May 23, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28532254/towards-the-recovery-of-a-sense-of-self-an-interpretative-phenomenological-analysis-of-patients-experience-of-body-oriented-psychotherapy-for-schizophrenia
#2
Laura Galbusera, Lisa Fellin, Thomas Fuchs
OBJECTIVE: Increasing evidence supports the efficacy of body-oriented psychotherapy (BPT) for schizophrenia. Yet, so far no research has investigated outcome in relation to therapy process: Why and how BPT is effective. In this study, we qualitatively explore participants' experience of a manualized BPT for schizophrenia to shed light on the process of therapeutic change. METHOD: We conducted in-depth interviews with 6 participants who completed a 10-week BPT group intervention...
May 22, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28531645/judgment-of-moral-and-social-transgression-in-schizophrenia
#3
Jonathan McGuire, Martin Brüne, Robyn Langdon
INTRODUCTION: Despite evidence of pervasive social-cognitive deficits in schizophrenia, little is known of moral cognition in this population. While recent research indicates that impairment of explicit moral reasoning is explained by these individuals' other cognitive deficits, their capacities for basic moral judgment are unknown. METHODS: 45 people with schizophrenia and 27 healthy controls completed the Moral-Conventional Distinction Task: a classic task that assesses judgment of violations of moral or social convention on permissibility, severity, and authority-contingence...
May 4, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28529122/shared-decision-making-a-buzz-word-in-the-netherlands-the-pace-quickens-towards-nationwide-implementation%C3%A2
#4
Trudy van der Weijden, Heleen Post, Paul L P Brand, Haske van Veenendaal, Ton Drenthen, Linda Aj van Mierlo, Peep Stalmeier, Olga C Damman, Anne Stiggelbout
Currently, shared decision making (SDM) is on the agenda among target patient representative groups, policy makers and professional bodies. Although the International Conference for Shared Decision Making (ISDM) 2011 generated a positive boost, hesitation was also felt among Dutch clinicians, who are challenged by many new tasks. No hesitation is seen among the majority of patients, opting mostly for the SDM model. We haven't reached these patients' needs fully yet, given disappointing research data on patients' experiences and professional behaviour...
May 18, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28527073/mindfulness-and-pharmacological-prophylaxis-have-comparable-effect-on-biomarkers-of-inflammation-and-clinical-indexes-in-chronic-migraine-with-medication-overuse-results-at-12%C3%A2-months-after-withdrawal
#5
Licia Grazzi, Domenico D'Amico, Alberto Raggi, Matilde Leonardi, Emilio Ciusani, Elena Corsini, Giovanni D'Andrea, Andrea Bolner, Francisco Salgado-García, Frank Andrasik, Emanuela Sansone
Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months' course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526013/human-biomonitoring-from-an-environmental-justice-perspective-supporting-study-participation-of-women-of-turkish-and-moroccan-descent
#6
Bert Morrens, Elly Den Hond, Greet Schoeters, Dries Coertjens, Ann Colles, Tim S Nawrot, Willy Baeyens, Stefaan De Henauw, Vera Nelen, Ilse Loots
BACKGROUND: Environmental justice research shows how socially disadvantaged groups are more exposed and more vulnerable to environmental pollution. At the same time, these groups are less represented and, thus, less visible in biomedical studies. This socioeconomic participation bias is a form of environmental injustice within research practice itself. METHODS: We designed, implemented and evaluated a targeted recruitment strategy to enhance the participation of socially disadvantaged pregnant women in a human biomonitoring study in Belgium...
May 19, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28523494/-a-future-amalgamation-between-the-scientist-and-the-clinician
#7
Sarah Haywood-Small
Personalized medicine is gaining momentum and analytical methods such as MS are ideally situated to provide coherent imaging of human disease. The cancer research field is already starting to benefit from the MS imaging applications; non-cancerous diseases will hopefully enjoy the same success. Often, the way forward is to embrace several techniques, which can complement and verify each other. This approach can be seen as less confrontational as everyone can play a part in the development of a new working practice...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28521557/metacognitive-verb-production-in-adolescents-the-link-to-complex-syntax
#8
Marilyn A Nippold, Laura M Vigeland, Megan W Frantz-Kaspar
Metacognitive verbs (MCVs) such as believe, know and think allow a speaker to describe the thoughts, feelings and perspectives of the self and others. As such, these words reflect the speaker's awareness of differing mental events and activities, or Theory of Mind (ToM). This study investigated the use of MCVs in adolescents with typical language development in relation to the production of complex sentences. It was of interest to determine the frequency with which adolescents used MCVs and to explore the links between MCVs and different types of subordinate clauses...
May 19, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28516959/adaptive-psychological-structure-in-childhood-hearing-impairment-audiological-correlations
#9
A Serra, G Spinato, S Cocuzza, L Licciardello, P Pavone, L Maiolino
The present research deals with the clinical and social problems present during linguistic and cognitive development of deaf children. Currently, the development of Theory of Mind represents an important research field in deafness studies. These international studies highlighted a significant alteration in the development of Theory of Mind in deaf children compared to normal hearing children, especially in cases of congenital or preverbal hearing loss. In particular, the research focuses on the skills of deaf children in recognising emotions and desires, through both perceptive and cognitive methods, by evaluation of psycho-cognitive skills of children with severe hearing loss using a set of questions to be administered to hearing loss patients...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28515799/implementing-mindfulness-in-the-mainstream-making-the-path-by-walking-it
#10
Rebecca S Crane
There is expanding interest in mindfulness-based programs (MBPs) within the mainstream. While there are research gaps, there is empirical evidence for these developments. Implementing new evidence into practice is always complex and difficult. Particular complexities and tensions arise when implementing MBPs in the mainstream. MBPs are emerging out of the confluence of different epistemologies-contemplative teaching and practice, and contemporary Western empiricism and culture. In the process of navigating implementation and integrity, and developing a professional practice context for this emerging field, the diverse influences within this confluence need careful attention and thought...
2017: Mindfulness
https://www.readbyqxmd.com/read/28513351/mind-the-fathers-associations-of-parental-childhood-adversities-with-borderline-personality-disorder-pathology-in-female-adolescents
#11
Corinna Reichl, Romuald Brunner, Anna Fuchs, Birger Holz, Peter Parzer, Gloria Fischer-Waldschmidt, Franz Resch, Michael Kaess
Previous research revealed significant relations between the experience of childhood adversity (CA) and the development of borderline personality disorder (BPD) in adulthood. However, it is still uncertain whether parental CA could have a transgenerational association with adolescent BPD. We investigated associations between parents' CA (antipathy, neglect, physical abuse) and BPD traits within a clinical adolescent sample and tested for mediating variables. The sample consists of 91 female inpatients, along with 84 mothers and 59 fathers...
May 17, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28513339/juggling-thoughts-and-feelings-how-do-female-patients-with-borderline-symptomology-and-substance-use-disorder-experience-change-in-mentalization-based-treatment
#12
Katharina T E Morken, Per Einar Binder, Nina Arefjord, Sigmund Karterud
OBJECTIVE: The aim of this study was to explore the experience of central psychological change processes for female patients with borderline symptomology and substance use disorder in mentalization-based treatment. METHOD: Semi-structured qualitative interviews on experiences from mentalization-based treatment with 13 participants were conducted. The interview material was analysed within a hermeneutical-phenomenological epistemology, with emphasis on researcher reflexivity...
May 17, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28512859/exploring-daily-affective-changes-in-university-students-with-a-mindful-positive-reappraisal-intervention-a-daily-diary-randomized-controlled-trial
#13
Ekaterina Pogrebtsova, Jacqueline Craig, Alexandra Chris, Deirdre O'Shea, M Gloria González-Morales
Brief and cost-effective interventions focused on emotion regulation techniques can buffer against stress and foster positive functioning. Mindfulness and positive reappraisal are two techniques that can mutually enhance one another to promote well-being. However, research testing the effectiveness of interventions combining mindfulness and reappraisal is lacking. The current pilot examined the effect of a combined mindful-reappraisal intervention on daily affect in a 5-day diary study with 106 university students...
May 17, 2017: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/28512119/complementary-and-integrative-medicine-in-the-management-of-headache
#14
REVIEW
Denise Millstine, Christina Y Chen, Brent Bauer
Headaches, including primary headaches such as migraine and tension-type headache, are a common clinical problem. Complementary and integrative medicine (CIM), formerly known as complementary and alternative medicine (CAM), uses evidence informed modalities to assist in the health and healing of patients. CIM commonly includes the use of nutrition, movement practices, manual therapy, traditional Chinese medicine, and mind-body strategies. This review summarizes the literature on the use of CIM for primary headache and is based on five meta-analyses, seven systematic reviews, and 34 randomized controlled trials (RCTs)...
May 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28508360/genome-to-phenome-a-systems-biology-approach-to-ptsd-using-an-animal-model
#15
Nabarun Chakraborty, James Meyerhoff, Marti Jett, Rasha Hammamieh
Post-traumatic stress disorder (PTSD) is a debilitating illness that imposes significant emotional and financial burdens on military families. The understanding of PTSD etiology remains elusive; nonetheless, it is clear that PTSD is manifested by a cluster of symptoms including hyperarousal, reexperiencing of traumatic events, and avoidance of trauma reminders. With these characteristics in mind, several rodent models have been developed eliciting PTSD-like features. Animal models with social dimensions are of particular interest, since the social context plays a major role in the development and manifestation of PTSD...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28506927/connecting-minds-and-sharing-emotions-through-mimicry-a-neurocognitive-model-of-emotional-contagion
#16
REVIEW
Eliska Prochazkova, Mariska E Kret
During social interactions, people tend to automatically align with or mimic their interactor's facial expressions, vocalizations, postures, and other bodily states. Automatic mimicry might be implicated in empathy, affiliation, and empathy, and is impaired in several pathologies. Despite a growing body of literature on its phenomenology, the function and underlying mechanisms of mimicry remain poorly understood. The current review puts forward a new Neurocognitive Model of Emotional Contagion (NMEC) demonstrating how basic automatic mimicry can give rise to emotional contagion...
May 12, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28506776/mindfulness-is-associated-with-treatment-response-from-non-pharmacological-exercise-interventions-in-knee-osteoarthritis
#17
Augustine C Lee, William F Harvey, Lori Lyn Price, Xingyi Han, Jeffrey B Driban, John B Wong, Mei Chung, Timothy E McAlindon, Chenchen Wang
OBJECTIVE: To examine the association between baseline mindfulness and response from exercise interventions in knee osteoarthritis (OA). DESIGN: Cohort Study; Responder analysis of a clinical trial subset SETTING: Urban tertiary care academic hospital PARTICIPANTS: 86 participants with symptomatic, radiographic knee OA (mean age, 60 years; 74% female; 48% white) INTERVENTIONS: 12 weeks (twice per week) of Tai Chi or Physical Therapy exercise MAIN OUTCOME MEASURE(S): Treatment response was defined using Osteoarthritis Research Society International criteria indicating meaningful improvements in the Western Ontario and McMaster Osteoarthritis Index (WOMAC) pain, function, or Patient Global Assessment scores...
May 12, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28505150/a-question-of-fate
#18
Mirjana Maletic-Savatic
Ever since the discovery of neural stem cells in the mammalian brain, the possibility of brain tissue regeneration has captured the minds of scientists, clinicians, and the public. Neural stem cells have been envisioned as a source of donor cells for transplantation and vectors for the delivery of gene therapy. Over the past decade, many researchers have contributed to characterizing these cells and their lineages, providing the foundation for their utilization as therapeutic devices. In a new study, Azim and colleagues took a different approach: using pharmacogenomics to focus on neural stem cell lineage, they identified specific compounds that can direct neural stem cell fate toward a specific lineage in vivo, both in physiological and pathological conditions...
May 2017: PLoS Biology
https://www.readbyqxmd.com/read/28504870/a-critical-evaluation-of-the-current-p-value-controversy
#19
REVIEW
Stefan Wellek
This article has been triggered by the initiative launched in March 2016 by the Board of Directors of the American Statistical Association (ASA) to counteract the current p-value focus of statistical research practices that allegedly "have contributed to a reproducibility crisis in science." It is pointed out that in the very wide field of statistics applied to medicine, many of the problems raised in the ASA statement are not as severe as in the areas the authors may have primarily in mind, although several of them are well-known experts in biostatistics and epidemiology...
May 15, 2017: Biometrical Journal. Biometrische Zeitschrift
https://www.readbyqxmd.com/read/28503039/the-possible-role-of-meditation-in-myofascial-pain-syndrome-a-new-hypothesis
#20
Prashanth Panta
BACKGROUND OF HYPOTHESIS: Myofascial pain syndrome (MPS) is the most common musculoskeletal pain disorder of the head and neck area. In the past, several theories were put forth to explain its origin and nature, but none proved complete. Myofascial pain responds to changing psychological states and stress, anxiety, lack of sleep, anger, depression and chronic pain are direct contributional factors. Myofascial pain syndrome may be considered as a psychosomatic disorder. There are numerous accepted palliative approaches, but of all, relaxation techniques stand out and initiate healing at the base level...
April 2017: Indian Journal of Palliative Care
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