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Mitraclip

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https://www.readbyqxmd.com/read/28645469/transcatheter-mitral-valve-repair-with-mitraclip-for-symptomatic-functional-mitral-valve-regurgitation
#1
REVIEW
Rodrigo Mendirichaga, Vikas Singh, Vanessa Blumer, Manuel Rivera, Alex P Rodriguez, Mauricio G Cohen, William W O'Neill, Sammy Elmariah
Transcatheter edge-to-edge mitral valve repair (TMVr) with MitraClip has proved to be safe and effective for high-risk surgical patients with severe symptomatic degenerative mitral regurgitation. There is paucity of data regarding its use in functional mitral regurgitation (FMR). The objective of this study was to evaluate the use of MitraClip in patients with symptomatic moderate or severe FMR and a high surgical risk. Medical libraries were systematically searched for studies assessing the use of MitraClip for patients with symptomatic moderate or severe FMR and a high surgical risk...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28625371/cardiovascular-events-and-hospital-resource-utilization-pre-and-post-transcatheter-mitral-valve-repair-in-high-surgical-risk-patients
#2
Sreekanth Vemulapalli, Steven J Lippmann, Mitchell Krucoff, Adrian F Hernandez, Lesley H Curtis, Elyse Foster, Atif Qasim, Andrew Wang, Donald D Glower, Ted Feldman, Bradley G Hammill
MitraClip is an approved therapy for mitral regurgitation (MR); however, health care resource utilization pre- and post-MitraClip remains understudied. METHODS: Patients with functional and degenerative MR at high surgical risk in the EVEREST II High-Risk Registry and REALISM Continued-Access Study were linked to Medicare data. Pre- and post-MitraClip all-cause death, stroke, myocardial infarction, heart failure (HF), and bleeding hospitalizations were identified. Inpatient costs, adjusted to 2010 US dollars, were calculated, and event rate ratios and cost ratios were estimated with multivariable modeling...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28612452/unusual-interatrial-membrane-in-the-left-atrium-a-newer-obstacle-for-transseptal-based-percutaneous-mitral-valve-repair-techniques
#3
Antonio Popolo Rubbio, Sarah Mangiafico, Salvatore Scandura, Sergio Buccheri, Marco Barbanti, Giuseppe Ronsivalle, Maria Elena Di Salvo, Marta Chiarandà, Tatiana Salerno, Anna Caggegi, Sandra Giaquinta, Davide Capodanno, Carmelo Grasso, Corrado Tamburino
We present a case of a patient with severe mitral regurgitation referred to our Institution for an echocardiographic examination as part of the routine workup to assess the eligibility for mitral valve percutaneous repair with either the MitraClip or Cardioband systems. Echocardiography showed the presence of an unusual interatrial membrane in the left atrium that represented a contraindication for the puncture of the interatrial septum. The patient was finally deferred to percutaneous mitral valve replacement using transapical access...
June 13, 2017: Echocardiography
https://www.readbyqxmd.com/read/28606884/transcatheter-mitral-annuloplasty-to-treat-residual-mitral-regurgitation-after-mitraclip-implantation
#4
Karina Brüstle, Maurizio Taramasso, Shingo Kuwata, Francesco Maisano
No abstract text is available yet for this article.
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28600091/transcatheter-aortic-valve-replacement-and-mitraclip-to-reverse-heart-failure
#5
REVIEW
Sukhdeep Basra, Molly Szerlip
Valvular heart diseases such as aortic stenosis and mitral regurgitation are often associated with heart failure, which in turn increases patients' Surgical Thoracic Society (STS) score. A high STS score means the patient is high risk for surgical aortic valve replacement and mitral valve repair/replacement. Transcatheter aortic valve replacement and percutaneous mitral valve repair offer a minimally invasive alternative for the treatment of valvular heart disease in patients with severe heart failure. We aim to review the current evidence on the safety, efficacy, and outcomes of these devices in patients with severe heart failure...
July 2017: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28589566/prevalence-of-optimal-valve-morphology-for-mitraclip-in-patients-with-mitral-regurgitation
#6
Juan Manuel Monteagudo Ruiz, Covadonga Fernández-Golfín, Dolores Mesa, Teresa González-Alujas, Marta Sitges, Fernando Carrasco-Chinchilla, Chi-Hion Li, Antonio Grande-Trillo, Amparo Martínez, Javier Matabuena, David Alonso-Rodríguez, Iolanda Aquila, José Luis Zamorano
AIMS: To evaluate how often patients with moderate-to-severe or severe mitral regurgitation (MR) meet the anatomical criteria for MitraClip implant and to examine the role of transthoracic echocardiography (TTE) for this task. METHODS AND RESULTS: From February to June 2015, all patients undergoing a TTE in nine Spanish hospitals were prospectively included. Patients with moderate-to-severe and severe mitral regurgitation were selected for analysis. Anatomical eligibility criteria for MitraClip were defined according to the EVEREST trial...
June 7, 2017: Echocardiography
https://www.readbyqxmd.com/read/28586413/role-of-the-tricuspid-regurgitation-after-mitraclip-and-transcatheter-aortic-valve-implantation-a-systematic-review-and-meta-analysis
#7
Rita Pavasini, Sara Ruggerini, Julia Grapsa, Simone Biscaglia, Carlo Tumscitz, Matteo Serenelli, Giuseppe Boriani, Angelo Squeri, Gianluca Campo
Aims: Treatment of tricuspid regurgitation (TR) is common after surgery for mitral and/or aortic valves. The prognostic role of moderate to severe TR in patients undergoing mitraclip or transcatheter aortic valve implantation (TAVI) is not well-defined. Thus, the aim of this article is to perform a systematic review and meta-analysis of articles valuing the prognostic role of TR for patients undergoing mitraclip and TAVI. Methods and results: Articles were searched in Pubmed, Cochrane Library, Google Scholar and Biomed Central in September 2016...
June 5, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28568427/left-ventricular-ejection-fraction-of%C3%A2-%C3%A2-20-too-bad-for-mitraclip%C3%A2
#8
Sebastian Barth, Martina B Hautmann, Sebastian Kerber, Frank Gietzen, Wilko Reents, Michael Zacher, Philipp Halbfass, Daniel P Griese, Bernhard Schieffer, Karsten Hamm
OBJECTIVES: This study sought to investigate whether the percutaneous mitral regurgitation (MR) reduction with the MitraClip® system in end-stage heart failure patients with a left ventricular ejection fraction (LVEF) of <20% also effects beneficial outcome or whether the underlying myogenic problem is leading and therefore of prognostic relevance. BACKROUND: The interventional treatment of functional mitral regurgitation (FMR) with the MitraClip(®) system could improve the clinical and hemodynamic outcome in patients with severely impaired left ventricular function...
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28566474/mitral-valve-repair-for-degenerative-mitral-valve-disease-surgical-approach-patient-selection-and-long-term-outcomes
#9
REVIEW
Gonçalo F Coutinho, Manuel J Antunes
Mitral valve repair (MVRepair) has become the procedure of choice to correct severe degenerative mitral regurgitation (MR), due to its documented superiority to valve replacement regarding long-term survival, freedom from valve-related adverse events and preservation of left ventricular (LV) function. The refinement of MVRepair techniques has rendered almost all valves (more than 95%) amenable to repair with a 15-year freedom from reoperation of 90%. The concept of 'centres of excellence for MVRepair' has emerged, encouraging referring doctors to select the most experienced institutions or individual surgeons to deal with the most complex cases, based on repair volume, appropriate peri-procedural imaging and data regarding expected outcomes (repair, mortality and durability of repair)...
May 31, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28544247/transcatheter-edge-to-edge-repair-of-anterior-mitral-flail-through-a-dehisced-annuloplasty-ring
#10
Edwin C Ho, Naveed Ahmed, Kim A Connelly, Neil P Fam
Recurrent mitral regurgitation (MR) due to mitral annuloplasty ring dehiscence is an uncommon late complication of surgery, and is associated with an increased risk of heart failure and mortality. We report the first application of MitraClip for recurrent primary MR and annuloplasty ring dehiscence in a patient with prohibitive surgical risk.
May 22, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28509760/global-longitudinal-strain-predicts-outcome-after-mitraclip-implantation-for-secondary-mitral-regurgitation
#11
Rodolfo Citro, Cesare Baldi, Patrizio Lancellotti, Angelo Silverio, Gennaro Provenza, Michele Bellino, Michele R Di Muro, Generoso Mastrogiovanni, Roberta De Rosa, Gennaro Galasso, Eduardo Bossone, Pietro Giudice, Federico Piscione
AIM: The aim of this study was to assess preoperative determinants, prevalence, and prognostic impact of left ventricular (LV) reverse remodeling (LVRR) in patients with secondary mitral regurgitation (SMR), undergoing MitraClip implantation (MCi). METHODS: From March 2012 to January 2015, a total of 41 consecutive patients with moderate-to-severe SMR treated successfully with MCi were enrolled. All patients underwent clinical and echocardiographic follow-up after MCi...
May 13, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28506547/transcatheter-mitral-valve-interventions-for-mitral-regurgitation-with-special-focus-on-mitraclip-the-position-of-spanish-portuguese-and-italian-interventional-societies
#12
Rodrigo Estévez-Loureiro, Xavier Freixa, Dabit Arzamendi, Armando Perez de Prado, Rui Campante-Teles, Bruno Melica, Giuseppe Tarantini, Giuseppe Musumeci, Manuel Pan
Mitral regurgitation is a common valvular heart disease and its prevalence is expected to increase with population ageing. In the recent years we have witnessed the evolution of several transcatheter devices to correct mitral regurgitation in patients at high-risk for surgery. Most of the evidence of the safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives have emerged with promising results. The aim of this position paper is to review the current evidence regarding patient selection, expected results and timing for transcatheter mitral valve interventions from the perspective of three European interventional societies...
May 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28504238/united-kingdom-coronary-and-structural-heart-interventions-from-2010-to-2015
#13
Peter F Ludman, Mark A de Belder, Simon Redwood, Adrian Banning
In the United Kingdom, a clinical data set is completed for every patient undergoing coronary intervention and certain structural interventions, and sent to central servers in the National Institute for Cardiovascular Outcomes Research (NICOR) on behalf of the British Cardiovascular Intervention Society (BCIS). These data are linked to the national mortality register. In addition, data are obtained about the structure of healthcare provision using an annual survey. Analyses of these data are provided for different audiences in several formats...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504231/poland-coronary-and-structural-heart-interventions-from-2010-to-2015
#14
Jacek Legutko, Zbigniew Siudak, Radosław Parma, Andrzej Ochała, Dariusz Dudek
For the last five years, invasive cardiology in Poland has developed extensively. Currently, 98% of the 161 Polish cathlabs operate in 24/7 mode, 37 of them supported by cardiac surgery departments on-site. A certification curriculum for interventional cardiology operators is supported by dedicated workshops and scientific meetings during national conferences. The rise in the number of coronary angiographies and PCIs was paralleled by an increased use of drug-eluting stents, bioresorbable vascular scaffolds and physiologic assessment of coronary arteries...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504228/italy-coronary-and-structural-heart-interventions-from-2010-to-2015
#15
Sergio Berti, Ferdinando Varbella, Alfredo Marchese, Luigi Emilio Pastormerlo, Giuseppe Musumeci
The aim of this report is to analyse trends in Italian cathlab activity between 2010 and 2015. Data were obtained from the national database of the Italian Society of Interventional Cardiology (GISE), which includes 97% of Italian cardiac catheterisation laboratories. The number of percutaneous coronary interventions (PCI) has remained relatively stable in the past five years. We have observed a significant increase in the number of primary PCI (pPCI) from 471.5 to 557.5 per million inhabitants with a consequent reduction of rescue primary PCI/fibrinolysis...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28485277/first-transjugular-edge-to-edge-mitral-valve-repair-with-the-mitraclip-system
#16
Neil P Fam, Edwin C Ho, Naveed Ahmed, Jeremy Edwards
No abstract text is available yet for this article.
May 9, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28481153/von-willebrand-factor-as-a-novel-player-in-valvular-heart-disease-from-bench-to-valve-replacement
#17
Felice Gragnano, Mario Crisci, Maurizio Cappelli Bigazzi, Renatomaria Bianchi, Simona Sperlongano, Francesco Natale, Fabio Fimiani, Claudia Concilio, Arturo Cesaro, Ivana Pariggiano, Vincenzo Diana, Giuseppe Limongelli, Plinio Cirillo, Mariagiovanna Russo, Enrica Golia, Paolo Calabrò
von Willebrand Factor (vWF) is a well-known mediator of hemostasis and vascular inflammation. Its dynamic modulation in the bloodstream, according to hemodynamic conditions, makes it an appealing biomarker in patients with valvular heart disease (VHD). Recent studies highlight the close connection between vWF and VHD, with possible implications in the pathogenesis of VHD, promoting valve aging and calcification or favoring the development of infective endocarditis. Moreover, vWF has been recently proposed as a new diagnostic and prognostic tool in patients with valve stenosis or regurgitation, showing a strict correlation with severity of valve disease, outcome, and bleeding (Heyde syndrome)...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28473117/assessing-the-balance-between-less%C3%A2-mitral%C3%A2-regurgitation-and-more-residual-transmitral-pressure-gradient%C3%A2-after%C3%A2-mitraclip
#18
EDITORIAL
Ted Feldman, Mayra Guerrero
No abstract text is available yet for this article.
May 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28473116/elevated-mitral-valve-pressure-gradient-after-mitraclip-implantation-deteriorates-long-term-outcome-in-patients-with-severe-mitral-regurgitation-and-severe%C3%A2-heart-failure
#19
Michael Neuss, Thomas Schau, Akihiro Isotani, Markus Pilz, Maren Schöpp, Christian Butter
OBJECTIVES: This single-center study was performed to analyze the effect of an increased transvalvular gradient after the MitraClip (MC) (Abbott Laboratories, Abbott Park, Illinois) procedure on patient outcome during follow-up. BACKGROUND: Percutaneous transcatheter repair of the mitral valve with the MC device has been established as a novel technique for patients with severe mitral regurgitation and high surgical risk. This study investigated the influence of an increased pressure gradient after MC implantation on the long-term outcome of patients...
May 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28457782/immediate-closure-of-iatrogenic-asd-after-mitraclip-procedure-prompted-by-acute-right-ventricular-dysfunction
#20
Lu Yeh, Azad Mashari, Mario Montealegre-Gallegos, Fernando Mujica, Jelliffe Jeganathan, Feroze Mahmood
No abstract text is available yet for this article.
February 7, 2017: Journal of Cardiothoracic and Vascular Anesthesia
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