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https://www.readbyqxmd.com/read/29026804/the-effect-of-cardamom-supplementation-on-serum-lipids-glycemic-indices-and-blood-pressure-in-overweight-and-obese-pre-diabetic-women-a-randomized-controlled-trial
#1
Yaghooblou Fatemeh, Fereydoun Siassi, Abbas Rahimi, Fariba Koohdani, Farideh Doostan, Mostafa Qorbani, Gity Sotoudeh
BACKGROUND: Spice consumption helps the treatment of diseases due to their antioxidant and anti-inflammatory contents. Cardamom is one of this spices; therefore, this study is designed to determine the effect of cardamom supplementation on serum lipids, glycemic indices, and blood pressure in pre-diabetic women. METHODS: Eighty overweight or obese pre-diabetic women were randomly allocated to two groups. The intervention group received 3 g of green cardamom and the placebo group received 3 g of rusk powder for 2 months...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/29021712/chronic-dietary-ginseng-extract-administration-ameliorates-antioxidant-and-cholinergic-systems-in-the-brains-of-aged-mice
#2
Mi Ra Lee, Jin Yeul Ma, Chang Keun Sung
BACKGROUND: Black ginseng has a more potent biological activity than non-steamed ginseng. We investigated the effects of long-term intake of dietary black ginseng extract (BG) on antioxidant activity in aged mice. We also compared the effects of BG on cognitive deficits with those of white ginseng extract (WG) and red ginseng extract (RG). METHODS: Ten-month-old mice were fed an AIN-93G-based diet containing 10 g/kg (low dose, L) or 30 g/kg (high dose, H) WG powder, RG powder, or BG powder for 24 wk...
October 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28990706/effect-of-dietary-supplementation-of-organic-zinc-on-laying-performance-egg-quality-and-some-biochemical-parameters-of-laying-hens
#3
M E Abd El-Hack, M Alagawany, S A Amer, M Arif, K M M Wahdan, M S El-Kholy
This study was conducted to evaluate the effects of zinc methionine (Zn-Met) supplementation on the performance, egg quality, antioxidant status and some biochemical parameters of blood serum in laying hens from 22 to 34 weeks of age. A total of 120 Hisex Brown laying hens of 22-week-old were randomly allocated into five treatments with six cage replicates for each (four hens/replicate). Dietary treatments consisted of the basal diet with no Zn-Met supplementation (control group) and basal diet supplemented with 25, 50, 75 or 100 mg Zn-Met/kg diet...
October 9, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28990504/polyphenols-in-food-cancer-prevention-and-apoptosis-induction
#4
Ashita Sharma, Mandeep Kaur, Jatinder Kaur Katnoria, Avinash Kaur Nagpal
Polyphenols are group of water-soluble organic compounds, mainly of natural origin. The compounds having about 5-7 aromatic rings and more than 12 phenolic hydroxyl groups are classified as polyphenols. These are the antioxidants which protect the body from oxidative damage. In plants, they are the secondary metabolites produced as a defense mechanism against stress factors. Antioxidant property of polyphenols is suggested to provide protection against many diseases associated with reactive oxygen species (ROS), including cancer...
October 6, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28988315/serum-gamma-glutamyltransferase-is-inversely-associated-with-dietary-total-and-coffee-derived-polyphenol-intakes-in-apparently-healthy-japanese-men
#5
Chie Taguchi, Yoshimi Kishimoto, Kazuo Kondo, Kazushige Tohyama, Toshinao Goda
PURPOSE: Serum γ-glutamyltransferase (GGT) has been proposed as a marker of oxidative stress. Here, we examined the association between serum GGT and the dietary intake of polyphenols, which have antioxidant properties. METHODS: A cross-sectional survey including 7960 apparently healthy Japanese men (aged 22-86 years) who participated in health checkups was conducted in Shizuoka, Japan. We analyzed these subjects' clinical serum parameters and lifestyle factors, including dietary polyphenol intake, which was evaluated by a self-administered questionnaire and by matching the subjects' food consumption data with our original polyphenol content database...
October 7, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28987589/hydroxy-selenomethionine-a-novel-organic-selenium-source-that-improves-antioxidant-status-and-selenium-concentrations-in-milk-and-plasma-of-mid-lactation-dairy-cows
#6
P Sun, J Wang, W Liu, D P Bu, S J Liu, K Z Zhang
This study aimed to evaluate the effect of hydroxy-selenomethionine (HMSeBA), a novel organic selenium (Se) source, on milk performance, antioxidative status, and Se concentrations in the milk and plasma of mid-lactation dairy cows compared with that of sodium selenite (SS). Fifty mid-lactation dairy cows with similar days in milk, milk yield, and parity received the same basal diet containing 0.06 mg of Se/kg of DM. They were assigned to 1 of 5 treatments according to a randomized complete block design: negative control (without Se supplementation), SS supplementation (0...
October 4, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28983399/carotenoids-as-potential-antioxidant-agents-in-stroke-prevention-a-systematic-review
#7
REVIEW
Ahmad Bahonar, Mohammad Saadatnia, Fariborz Khorvash, Mohammadreza Maracy, Alireza Khosravi
Stroke and other cerebrovascular diseases are among the most common causes of death worldwide. Prevention of modifiable risk factors is a cost-effective approach to decrease the risk of stroke. Oxidative stress is regarded as the major flexible operative agent in ischemic brain damage. This review presents recent scientific advances in understanding the role of carotenoids as antioxidants in lowering stroke risk based on observational studies. We searched Medline using the following terms: (Carotenoids [MeSH] OR Carotenes [tiab] OR Carotene [tiab] OR "lycopene [Supplementary Concept]" [MeSH] OR lycopene [tiab] OR beta-Carotene [tiab]) AND (stroke [MeSH] OR stroke [tiab] OR "Cerebrovascular Accident" [tiab] OR "Cerebrovascular Apoplexy" [tiab] OR "Brain Vascular Accident" [tiab] OR "Cerebrovascular Stroke" [tiab]) AND ("oxidative stress" [MeSH] OR "oxidative stress"[tiab])...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28981464/associations-of-dietary-antioxidants-and-risk-of-type-2-diabetes-data-from-the-2007-2012-korea-national-health-and-nutrition-examination-survey
#8
Dan Yedu Quansah, Kyungho Ha, Shinyoung Jun, Seong-Ah Kim, Sangah Shin, Gyung-Ah Wie, Hyojee Joung
Antioxidants are suggested to decrease risk of type 2 diabetes (T2D) by preventing progressive impairment of pancreatic β-cell and endothelial function. This study was aimed to investigate the association between dietary antioxidants and risk of T2D in Korean adults based on a national representative data. A total of 24,377 adults (19-74 years) who completed one-day 24 h dietary recall and health examination were included. Dietary antioxidant intakes including α-carotene (p < 0.0001), lycopene (p = 0.0107), flavan-3-ols (p < 0...
October 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28980870/comparison-of-myo-inositol-and-metformin-on-mental-health-parameters-and-biomarkers-of-oxidative-stress-in-women-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#9
Hamidreza Jamilian, Mehri Jamilian, Fatemeh Foroozanfard, Faraneh Afshar Ebrahimi, Fereshteh Bahmani, Zatollah Asemi
INTRODUCTION: Data on comparison of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with polycystic ovary syndrome (PCOS) are scarce. This purpose of this study was to compare of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in subjects with PCOS. METHODS: This randomized controlled trial was conducted among 60 subjects diagnosed with PCOS according to the Rotterdam criteria...
October 5, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28970338/novel-loci-underlie-natural-variation-in-vitamin-e-levels-in-maize-grain
#10
Christine H Diepenbrock, Catherine B Kandianis, Alexander E Lipka, Maria Magallanes-Lundback, Brieanne Vaillancourt, Elsa Góngora-Castillo, Jason G Wallace, Jason Cepela, Alex Mesberg, Peter Bradbury, Daniel C Ilut, Maria Mateos-Hernandez, John Hamilton, Brenda F Owens, Tyler Tiede, Edward S Buckler, Torbert Rocheford, C Robin Buell, Michael A Gore, Dean DellaPenna
Tocopherols, tocotrienols and plastochromanols (collectively termed tocochromanols) are lipid-soluble antioxidants synthesized by all plants. Their dietary intake, primarily from seed oils, provides vitamin E and other health benefits. Tocochromanol biosynthesis has been dissected in the dicot Arabidopsis thaliana, which has green, photosynthetic seeds, but our understanding of tocochromanol accumulation in major crops, whose seeds are non-photosynthetic, remains limited. To understand the genetic control of tocochromanols in grain, we conducted a joint linkage and genome-wide association study in the 5,000-line U...
October 2, 2017: Plant Cell
https://www.readbyqxmd.com/read/28969360/proposed-mechanisms-of-the-effects-of-proanthocyanidins-on-glucose-homeostasis
#11
Kaiyuan Yang, Catherine B Chan
Proanthocyanidins are a major group of flavonoids in the human diet, known for their strong antioxidant properties. Emerging evidence from clinical studies indicates a role of proanthocyanidins in modulating glucose homeostasis, and higher proanthocyanidin intake has been associated with reduced risk of diabetes. On the other hand, recent studies report limited bioavailability of proanthocyanidins. At relatively low concentrations in the systemic circulation, proanthocyanidins may act as cell-signaling molecules to modulate glucose homeostasis...
August 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28968965/association-between-single-nucleotide-polymorphisms-in-the-antioxidant-genes-cat-gr-and-sod1-erythrocyte-enzyme-activities-dietary-and-life-style-factors-and-breast-cancer-risk-in-a-danish-prospective-cohort-study
#12
Tine Iskov Kopp, Ulla Vogel, Lars Ove Dragsted, Anne Tjonneland, Gitte Ravn-Haren
Exposure to estrogens and alcohol consumption - the two only well-established risk factors for breast cancer - are capable of causing oxidative stress, which has been linked to progression of breast cancer. Here, five functional polymorphisms in the antioxidant genes SOD1, CAT and GSR were investigated in 703 breast cancer case-control pairs in the Danish, prospective "Diet, Cancer and Health" cohort together with gene-environment interactions between the polymorphisms, enzyme activities and intake of fruits and vegetables, alcohol and smoking in relation to breast cancer risk...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28965606/mineral-status-and-superoxide-dismutase-enzyme-activity-in-alzheimer-s-disease
#13
Gilmara Péres Rodrigues, Silvia Maria Franciscato Cozzolino, Dilina do Nascimento Marreiro, Daniele Rodrigues Carvalho Caldas, Kelcylene Gomes da Silva, Kaluce Gonçalves de Sousa Almondes, José Machado Moita Neto, José Alexandre Coelho Pimentel, Cecília Maria Resende Gonçalves de Carvalho, Nadir do Nascimento Nogueira
The study evaluated the dietary intake of zinc and copper, as measured by plasma and erythrocyte concentrations, the Cu/Zn ratio and measure the erythrocyte superoxide dismutase enzyme (eSOD) activity and the relationship between these markers and the degree of dementia in elderly individuals with and without Alzheimer's Disease (AD). A total of 93 elderly people aged 60-94 years were divided into two groups: with AD (n=44) and without AD (n=49). The NINCDS-ADRDA criteria were used for diagnosing AD, and dementia staging was determined using the Clinical Dementia Rating (CDR) scale...
December 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28965599/selenium-protein-identification-and-profiling-by-mass-spectrometry-a-tool-to-assess-progression-of-cardiomyopathy-in-a-whale-model
#14
Colleen E Bryan, Gregory D Bossart, Steven J Christopher, W Clay Davis, Lisa E Kilpatrick, Wayne E McFee, Terrence X O'Brien
Non-ischemic cardiomyopathy is a leading cause of congestive heart failure and sudden cardiac death in humans and in some cases the etiology of cardiomyopathy can include the downstream effects of an essential element deficiency. Of all mammal species, pygmy sperm whales (Kogia breviceps) present the greatest known prevalence of cardiomyopathy with more than half of examined individuals indicating the presence of cardiomyopathy from gross and histo-pathology. Several factors such as genetics, infectious agents, contaminants, biotoxins, and inappropriate dietary intake (vitamins, selenium, mercury, and pro-oxidants), may contribute to the development of idiopathic cardiomyopathy in K...
December 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28964663/saffron-crocus-sativus-intake-provides-nutritional-preconditioning-against-myocardial-ischemia-reperfusion-injury-in-wild-type-and-apoe-mice-involvement-of-nrf2-activation
#15
P Efentakis, A Rizakou, E Christodoulou, A Chatzianastasiou, M G López, R León, E Balafas, N P E Kadoglou, I Tseti, H Skaltsa, N Kostomitsopoulos, E K Iliodromitis, G Valsami, I Andreadou
BACKGROUND AND AIMS: Saffron is an antioxidant herbal derivative; however, its efficacy as a nutritional cardioprotective agent has not been fully elucidated. We investigated the cardioprotective properties of a standardized saffron aqueous extract (SFE) against ischemia/reperfusion (I/R) injury in Wild-Type (WT) and ApoE((-/-)) mice and the underlying molecular mechanisms. METHODS AND RESULTS: WT and ApoE((-/-)) mice were subjected to 30 min I and 2 h R, with the following per os interventions for 4 weeks: 1) WT Control Group, receiving Water for Injection (WFI); 2) WT Crocus Group, receiving SFE at a dose of 60 mg/kg/day; 3) WT Crocus + Wort group, receiving SFE as described above and wortmannin at a dose of 60 μg/kg bolus 15 min before R; 4) ApoE((-/-)) Control Group, receiving WFI; 5) ApoE((-/-)) Crocus Group, receiving SFE at a dose of 60 mg/kg/day and 6) ApoE((-/-)) Crocus + Wort: receiving SFE as described above and wortmannin at a dose of 60 μg/kg bolus, 15 min before R...
October 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28964373/phenolic-composition-profiling-of-different-edible-parts-and-by-products-of-date-palm-phoenix-dactylifera-l-by-using-hplc-dad-esi-ms-n
#16
Ibrahim M Abu-Reidah, Ángel Gil-Izquierdo, Sonia Medina, Federico Ferreres
Fruits and vegetables are an important source of dietary antioxidants and epidemiological studies show that their regular intake in the diet may decrease the risk of several chronic diseases. Phoenix dactylifera L. (date palm or dates) is an important crop, widely used in the Arabian region and in other parts of the world as a food and also in folk medicine, due to its health-promoting properties. Antioxidant phytochemicals present in plant foods are partly responsible for such health benefits. The antioxidants present in dates are mainly phenolics, like flavonoids and phenolic acids...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28963619/the-effect-of-vitamin-e-l-carnitine-and-ginger-on-production-traits-immune-response-and-antioxidant-status-in-two-broiler-strains-exposed-to-chronic-heat-stress
#17
Zia Ur Rehman, Naila Chand, Rifat Ullah Khan
The present study was designed to find the effect of natural and synthetic antioxidants on the performance of two broiler strains under high ambient temperature. A total of 320 day-old chicks of Hubbard and Cobb were reared for a period for 21 days under the same nutritional and management systems. On day 21 onward, one subgroup was kept as control while other subgroups were provided with vitamin E (250 mg/kg), ginger (2 g/kg), and L-carnitine (500 mg/kg) in basal diets. Body weight and feed conversion ratio (FCR) were significantly (P < 0...
September 30, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28963592/effect-of-dietary-betaine-on-growth-performance-antioxidant-capacity-and-lipid-metabolism-in-blunt-snout-bream-fed-a-high-fat-diet
#18
Jean-Jacques Yao Adjoumani, Kaizhou Wang, Man Zhou, Wenbin Liu, Dingdong Zhang
An 8-week feeding experiment was conducted to determine the effect of dietary betaine levels on the growth performance, antioxidant capacity, and lipid metabolism in high-fat diet-fed blunt snout bream (Megalobrama amblycephala) with initial body weight 4.3 ± 0.1 g [mean ± SEM]. Five practical diets were formulated to contain normal-fat diet (NFD), high-fat diet (HFD), and high-fat diet with betaine addition (HFB) at difference levels (0.6, 1.2, 1.8%), respectively. The results showed that the highest final body weight (FBW), weight gain ratio (WGR), specific growth rate (SGR), condition factor (CF), and feed intake (FI) (P < 0...
September 30, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28961515/the-ameliorating-effects-of-selenium-and-vitamin-c-against-fenitrothion-induced-blood-toxicity-in-wistar-rats
#19
Marija D Milošević, Milica G Paunović, Miloš M Matić, Branka I Ognjanović, Zorica S Saičić
Fenitrothion is widely used organophosphate pesticide in agriculture and health programs, but besides, it causes several toxic effects. The present study was designed to evaluate the possible protective effects of selenium (0.5mg/kg b.w.) and vitamin C (100mg/kg b.w) on altered haematological, biochemical and oxidative stress parameters in the blood of rats orally treated with fenitrothion (20mg/kg b.w) for 30days. Fenitrothion caused changes in body weight, food and water intake, and some haematological and biochemical parameters...
September 21, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28958110/clinical-trial-on-the-effects-of-vitamin-d-supplementation-on-metabolic-profiles-in-diabetic-hemodialysis
#20
Mohammad Reza Tamadon, Alireza Soleimani, Fariba Keneshlou, Malihe Zarrati Mojarrad, Fereshteh Bahmani, Afshin Naseri, Hamed Haddad Kashani, Elahe Seyed Hosseini, Zatollah Asemi
The current study was conducted to assess the effects of vitamin D supplementation on insulin metabolism, lipid fractions, biomarkers of inflammation, and oxidative stress in diabetic hemodialysis (HD) patients. This randomized double-blind placebo-controlled clinical trial was carried out among 60 diabetic HD patients. Subjects were randomly allocated into two groups to intake either oral vitamin D3 supplements at a dosage of 50 000 IU (n=30) or placebo (n=30) every 2 weeks for 12 weeks. After 12 weeks of intervention, subjects who received vitamin D supplements compared with the placebo had significantly decreased serum insulin concentrations (-3...
September 28, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
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