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https://www.readbyqxmd.com/read/29470421/phytochemicals-in-human-milk-and-their-potential-antioxidative-protection
#1
REVIEW
Apollinaire Tsopmo
Diets contain secondary plant metabolites commonly referred to as phytochemicals. Many of them are believed to impact human health through various mechanisms, including protection against oxidative stress and inflammation, and decreased risks of developing chronic diseases. For mothers and other people, phytochemical intake occurs through the consumption of foods such as fruits, vegetables, and grains. Research has shown that some these phytochemicals are present in the mother's milk and can contribute to its oxidative stability...
February 22, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29470134/the-effect-of-aronia-berry-on-type-1-diabetes-in-vivo-and-in-vitro
#2
Yong-Deok Jeon, Sa-Haeng Kang, Kwang-Hyun Moon, Jeong-Ho Lee, Dae-Geun Kim, Wook Kim, Jong-Sung Kim, Byung-Yong Ahn, Jong-Sik Jin
The number of diabetic patients worldwide is increasing, and complications such as stroke and cardiovascular disease are becoming a serious cause of death. Diabetes mellitus is classified into two types according to the etiopathogenic mechanism and insulin dependence. Type 1 diabetes (T1D), an insulin-dependent diabetes mellitus, is caused by damage and destruction of pancreatic β cells that produce insulin. It is a disease that is characterized by hyperglycemia and hypoinsulinemia. Aronia berry has been used as a medicinal food in Europe...
February 22, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29469027/reduced-mortality-risk-by-a-polyphenol-rich-diet-an-analysis-from-the-moli-sani-study
#3
George Pounis, Simona Costanzo, Marialaura Bonaccio, Augusto Di Castelnuovo, Amalia de Curtis, Emilia Ruggiero, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
OBJECTIVES: The effect of the polyphenol content of the human diet on mortality risk is not yet fully understood. The aim of this study was to evaluate the association of a polyphenol-rich diet with mortality rate and a possible mediation effect by inflammation, in what we believe to be a novel, holistic approach. METHODS: We analyzed 21 302 participants (10 980 women and 10 322 men, aged ≥35 y) from the Moli-sani cohort. The participants were followed up for a median of 8...
November 28, 2017: Nutrition
https://www.readbyqxmd.com/read/29465424/nutritional-approach-to-preeclampsia-prevention
#4
Najate Achamrah, Agnès Ditisheim
PURPOSE OF REVIEW: Although not fully understood, the physiopathology of preeclampsia is thought to involve abnormal placentation, diffuse endothelial cell dysfunction and increased systemic inflammation. As micronutrients play a key role in placental endothelial function, oxidative stress and expression of angiogenic factors, periconceptional micronutrient supplementation has been proposed to reduce the risk of preeclampsia. However, recent studies reported conflicting results. RECENT FINDINGS: Calcium intake (>1 g/day) may reduce the risk of preeclampsia in women with low-calcium diet...
February 19, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29462462/effects-of-supplementation-with-%C3%AE-tocopherol-ascorbic-acid-selenium-or-their-combination-in-linseed-oil-enriched-diets-on-the-oxidative-status-in-broilers
#5
J Leskovec, A Levart, A Nemec Svete, L Peric, M Ðukic Stojcic, D Žikic, J Salobir, V Rezar
A trial was conducted to investigate whether, and if so to what extent, the combined supplementation of vitamin E, vitamin C, and selenium was superior to their sole supplementation concerning the oxidative stress induced by a high n-3 dietary polyunsaturated fatty acids (PUFA) intake in broilers. Four hundred 21-day-old Ross 308 male broilers were allocated to 5 experimental groups fed the following linseed oil (5%)-enriched finisher diets: Cont (no supplement), +E (200 IU vitamin E/kg feed), +C (250 mg vitamin C/kg feed), +Se (0...
February 15, 2018: Poultry Science
https://www.readbyqxmd.com/read/29461678/the-relation-between-dietary-intake-and-glaucoma-a-systematic-review
#6
REVIEW
Wishal D Ramdas
PURPOSE: A common question of patients to their physician is what they can do themselves against glaucoma, except taking their daily medication. However, for ophthalmologists, it is often hard to give their patients an advice on their dietary intake. To help ophthalmologists in answering this question, an overview of the current scientific literature on the association of nutrients with glaucoma is presented. METHODS: A comprehensive systematic review was conducted in which articles published up to September 2017 were identified in PubMed and reference lists...
February 20, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29459874/traversing-the-links-between-heavy-metal-stress-and-plant-signaling
#7
REVIEW
Siddhi K Jalmi, Prakash K Bhagat, Deepanjali Verma, Stanzin Noryang, Sumaira Tayyeba, Kirti Singh, Deepika Sharma, Alok K Sinha
Plants confront multifarious environmental stresses widely divided into abiotic and biotic stresses, of which heavy metal stress represents one of the most damaging abiotic stresses. Heavy metals cause toxicity by targeting crucial molecules and vital processes in the plant cell. One of the approaches by which heavy metals act in plants is by over production of reactive oxygen species (ROS) either directly or indirectly. Plants act against such overdose of metal in the environment by boosting the defense responses like metal chelation, sequestration into vacuole, regulation of metal intake by transporters, and intensification of antioxidative mechanisms...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29459509/study-of-trans-fatty-acid-formation-in-oil-by-heating-using-model-compounds
#8
Naohiro Gotoh, Satoshi Kagiono, Kazuaki Yoshinaga, Hoyo Mizobe, Toshiharu Nagai, Akihiko Yoshida, Fumiaki Beppu, Koji Nagao
The intake of trans fatty acids (TFAs) in foods changes the ratio of low density lipoprotein (LDL) to high density lipoprotein (HDL) cholesterol in blood, which causes cardiovascular disease. TFAs are formed by trans isomerization of unsaturated fatty acids (UFAs). The most recognized formation mechanisms of TFAs are hydrogenation of liquid oil to form partially hydrogenated oil (PHO,) and biohydrogenation of UFAs to form TFA in ruminants. Heating oil also forms TFAs; however, the mechanism of formation, and the TFA isomers formed have not been well investigated...
February 19, 2018: Journal of Oleo Science
https://www.readbyqxmd.com/read/29455342/pre-protective-effects-of-dietary-chitosan-supplementation-against-oxidative-stress-induced-by-diquat-in-weaned-piglets
#9
Y Q Xu, Y Y Xing, Z Q Wang, S M Yan, B L Shi
The protective effects of chitosan (CS) supplementations on oxidative stress induced by diquat in weaned piglets were investigated. A total of 36 crossbreed piglets with an average live body weight (BW) of 8.80 ± 0.53 kg were weaned at 28 ± 2 days and randomly divided into six dietary treatments (n = 6): control (basal diet), negative control (10 mg diquat/kg BW injected to piglets fed with basal diet), and basal diet treatments containing either 250, 500, 1000, or 2000 mg/kg of CS administered to piglets injected with 10 mg diquat/kg BW...
February 17, 2018: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29454898/dietary-values-of-forsythia-suspensa-extract-in-penaeus-monodon-under-normal-rearing-and-vibrio-parahaemolyticus-3hp-vp-3hp-challenge-conditions-effect-on-growth-intestinal-barrier-function-immune-response-and-immune-related-gene-expression
#10
Jia-Jun Xie, Xu Chen, Tian-Yu Guo, Shi-Wei Xie, Hao-Hang Fang, Zhen-Lu Liu, Yan-Mei Zhang, Li-Xia Tian, Yong-Jian Liu, Jin Niu
Two trials were conducted to determine the effects of dietary Forsythia suspensa extract (FSE) on shrimp, Penaeus monodon, first on growth performance, second on the immune response and immune related gene expression of shrimp. In trial 1, shrimp (mean initial wet weight about 3.02 g) were fed with five diets containing 0% (basal diet), 0.01%, 0.02%, 0.04% and 0.06% FSE in triplicate for 60 days. Growth performance (final body wet weight, FBW; weight gain, WG; biomass gain, BG) of shrimp fed FSE diets were higher (P < 0...
February 15, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29454678/treatment-of-coenzyme-q10-for-24-weeks-improves-lipid-and-glycemic-profile-in-dyslipidemic-individuals
#11
Peiwen Zhang, Chen Yang, Honghui Guo, Jiaji Wang, Shengqiang Lin, Huamei Li, Yan Yang, Wenhua Ling
BACKGROUND: The use of coenzyme Q10 (CoQ10) as an adjuvant treatment with routine clinical therapy against metabolic diseases has shown benefit. However, the effect of CoQ10 as a primary preventive agent against cardiovascular diseases (CVDs) has not been well studied. OBJECTIVE: The objective of this study was to investigate the effect of CoQ10 on CVD risk factors in dyslipidemic patients. METHODS: In this randomized, double-blinded, placebo-controlled trial, 101 dyslipidemic subjects without taking any hypoglycemic or hypolipidemic drugs were administrated to 120 mg CoQ10 or placebo daily for 24 weeks...
December 21, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29452404/vitamin-e-and-vitamin-c-supplementation-improves-antioxidant-status-and-immune-function-in-oxidative-stressed-breeder-roosters-by-up-regulating-expression-of-gsh-px-gene
#12
Y N Min, Z Y Niu, T T Sun, Z P Wang, P X Jiao, B B Zi, P P Chen, D L Tian, F Z Liu
This study aimed to evaluate the effects of vitamin C and vitamin E on antioxidant capacity and immune function in oxidative-stressed breeder roosters. One hundred twenty 45-week-old Lveyang black-boned breeder roosters were randomly assigned to 5 dietary treatments, including negative control group (NC), positive control group (PC), and 3 trial groups, which were fed the diets containing 300 mg/kg VC, 200 mg/kg VE, or 300 mg/kg VC and 200 mg/kg VE (VC+VE). At 47 wk of age, the positive control and trial groups were subcutaneously injected 3 times every other d with dexamethasone (DEX) 4 mg/kg of body weight, the negative control group was injected with saline...
February 14, 2018: Poultry Science
https://www.readbyqxmd.com/read/29450137/liver-and-metformin-lessons-of-a-fructose-diet-in-mice
#13
Iara Karise, Fernanda Ornellas, Sandra Barbosa-da-Silva, Cristiane Matsuura, Mariano Del Sol, Marcia Barbosa Aguila, Carlos A Mandarim-de-Lacerda
Studies show that the continuous consumption of fructose can lead to nonalcoholic fatty liver disease (NAFLD) and steatohepatitis. We aimed to investigate the role of Metformin in an animal model of liver injury caused by fructose intake, focusing on the molecular markers of lipogenesis, beta-oxidation, and antioxidant defenses. Male three months old C57BL/6 mice were divided into control group (C) and fructose group (F, 47% fructose), maintained for ten weeks. After, the groups received Metformin or vehicle for a further eight weeks: control (C), control + Metformin (CM), fructose (F), and fructose + Metformin (FM)...
June 2017: Biochimie open
https://www.readbyqxmd.com/read/29445913/dietary-pattern-associated-with-selenoprotein-p-and-mri-derived-body-fat-volumes-liver-signal-intensity-and-metabolic-disorders
#14
Romina di Giuseppe, Sandra Plachta-Danielzik, Manja Koch, Ute Nöthlings, Sabrina Schlesinger, Jan Borggrefe, Marcus Both, Hans-Peter Müller, Jan Kassubek, Gunnar Jacobs, Wolfgang Lieb
PURPOSE: The association of complex dietary patterns with circulating selenoprotein P (SELENOP) levels in humans is unknown. In a general population sample, we aimed to identify a dietary pattern explaining inter-individual variation in circulating SELENOP concentrations and to study this pattern in relation to prevalent diabetes, metabolic syndrome (MetS), MRI-determined total volumes of visceral (VAT) and subcutaneous (SAT) abdominal adipose tissue, and liver signal intensity/fatty liver disease...
February 14, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29437027/benefits-of-olive-oil-phenolic-compounds-in-disease-prevention
#15
Olga Garcia-Martinez, Concepcion Ruiz, Alvaro Gutierrez-Ibanez, Rebeca Illescas-Montes, Lucia Melguizo-Rodriguez
BACKGROUND AND OBJECTIVE: The preventive effects of olive oil against different diseases have been attributed to its high phenolic compound content. The objective of this study was to examine available scientific evidence on the beneficial effects against chronic diseases of olive oil phenolic compounds. METHOD: This article examines recently published data on olive oil phenolic compounds and their potential benefits in the prevention of cardiovascular disease, cancer, neurodegenerative disease, and osteoporosis...
February 12, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29435281/effect-of-anthocyanin-rich-bilberry-extract-on-bone-metabolism-in-ovariectomized-rats
#16
Saki Shimizu, Hiroshi Matsushita, Yuko Morii, Yuriko Ohyama, Noriko Morita, Rika Tachibana, Kazushi Watanabe, Akihiko Wakatsuki
Menopause is associated with increased oxidative stress, which serves a role, in part, in the pathogenesis of postmenopausal bone loss. Fruits and vegetables are rich in antioxidative nutrients and phytochemicals. Berries are a natural source of anthocyanins, and their intake may improve bone health. The aim of the present study was to determine the effect of an anthocyanin-rich bilberry extract (VME) on bone metabolism in an ovariectomized (Ovx) rat. Female Sprague-Dawley rats (12 weeks old) were randomly divided into the following four groups: Baseline, Sham, Ovx and Ovx+VME (n=8-12 rats per group)...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29433248/a-preliminary-exploration-of-the-potential-of-eugenia-uvalha-cambess-juice-intake-to-counter-oxidative-stress
#17
J M M Lopes, N N Lage, J F C Guerra, M Silva, L F Bonomo, A H S Paulino, A L R S Regis, M L Pedrosa, M E Silva
PURPOSE: The ability of foods to aid in the prevention of chronic metabolic diseases, has recently become an area of increased interest. In addition, there is growing interest in exploring the benefits of consuming underutilized fruits as alternatives to commercially available fruits. Eugenia uvalha Cambess (uvaia) is a native fruit of Brazil with great market and phytotherapy potential. The present study was conducted to investigate the effects of uvaia juice (UJ) on the levels of protein carbonyls (PCO) and antioxidant enzymes in the livers of rats fed a high-fat diet...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29432741/dietary-nitrate-protects-submandibular-gland-from-hyposalivation-in-ovariectomized-rats-via-suppressing-cell-apoptosis
#18
Yipu Xu, Baoxing Pang, Liang Hu, Xiaoyu Feng, Lei Hu, Jingsong Wang, Chunmei Zhang, Songlin Wang
Xerostomia, a major oral symptom of menopause, is a subjective feeling of dry mouth associated with oral pain and difficulties in deglutition and speech, which significantly reduces patient's quality of life. Dietary nitrate, which can be converted to nitric oxide, has multiple physiological functions in the body, including antioxidant activity and vasodilatation; however, its protective effect against xerostomia remains poorly understood. The present study aimed to evaluate the effects of dietary nitrate on estrogen deficiency-induced xerostomia...
February 9, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29432056/consumption-of-soymilk-reduces-lipid-peroxidation-but-may-lower-micronutrient-status-in-apparently-healthy-individuals
#19
Anaelechi J Onuegbu, Japhet M Olisekodiaka, Sylvia E Irogue, Ubuo K Amah, John E Okwara, Olubunmi G Ayelagbe, Christian E Onah
Consumption of soy products is speculated to reduce the risk and progression of some disease conditions. The underlying mechanisms mediating this effect are uncertain, but the lowering of oxidative stress has been suggested. This study was aimed at investigating the effect of soymilk on antioxidant status and lipid peroxidation in apparently healthy individuals. Five hundred milliliters of soymilk was taken daily by each of 39 apparently healthy individuals for a period of 28 days. Two sets of blood samples (baseline and after 28 days of soymilk intake) were collected and assayed for total antioxidant capacity (TAC), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione S-transferase (GST), manganese (Mn) and zinc (Zn) levels, using standard methods...
February 12, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29430988/protective-effect-of-d-methionine-on-body-weight-loss-anorexia-and-nephrotoxicity-in-cisplatin-induced-chronic-toxicity-in-rats
#20
Ming-Tai Lin, Jiunn-Liang Ko, Te-Chung Liu, Pei-Tsen Chao, Chu-Chyn Ou
D-methionine is a sulfur-containing amino acid that can act as a potent antioxidant. Anorexia and nephrotoxicity are side effects of cisplatin. The protective effects of D-methionine on cisplatin-induced anorexia and renal injury were investigated. The model of chronic cisplatin administration (5 mg/kg body weight) involved intraperitoneal injection on days 1, 8, and 15 and oral D-methionine (300 mg/kg body weight) coadministration daily for 20 days. On the 21st day of treatment, food intake and body weight in the cisplatin-treated group significantly decreased by 52% and 31%, respectively, when compared with a control group...
February 1, 2018: Integrative Cancer Therapies
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