keyword
MENU ▼
Read by QxMD icon Read
search

pirferidon

keyword
https://www.readbyqxmd.com/read/28739802/tgf-%C3%AE-1-regulates-the-expression-and-transcriptional-activity-of-taz-protein-via-a-smad3-independent-myocardin-related-transcription-factor-mediated-mechanism
#1
Maria Zena Miranda, Janne Folke Bialik, Pam Speight, Qinghong Dan, Tony Yeung, Katalin Szászi, Stine F Pedersen, András Kapus
Hippo pathway transcriptional coactivators TAZ and YAP and the TGF-β1 (TGFβ) effector Smad3 regulate a common set of genes, can physically interact, and exhibit multilevel cross-talk regulating cell fate-determining and fibrogenic pathways. However, a key aspect of this cross-talk, TGFβ-mediated regulation of TAZ or YAP expression, remains uncharacterized. Here, we show that TGFβ induces robust TAZ but not YAP protein expression in both mesenchymal and epithelial cells. TAZ levels, and to a lesser extent YAP levels, also increased during experimental kidney fibrosis...
September 8, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27971551/cost-utility-of-nintedanib-vs-pirferidone-in-the-treatment-of-idiopathic-pulmonary-fibrosis-in-spain
#2
S Soulard, C Crespo
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/11245776/urinary-tract-obstruction
#3
REVIEW
S Klahr
Angiotensin II plays a pivotal role in the progression of renal diseases, including obstructive nephropathy. Increasing levels of angiotensin II in obstructive nephropathy upregulate the expression of several factors: transforming growth factor-beta1 (TGF-beta1), tumor necrosis factor-alpha (TNF-alpha), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF-1), osteopontin, vascular cell adhesion molecule-1 (VCAM-1), nuclear factor-kappaB (NF-kappaB), monocyte chemoattractant peptide-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), and CD14 among others...
March 2001: Seminars in Nephrology
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"