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https://www.readbyqxmd.com/read/29068705/campaign-preparation-for-complex-initiatives-a-person-centered-approach-to-audience-segmentation-of-parents-antibiotic-stewardship
#1
Rachel A Smith, Erina L MacGeorge, Nicole M Hackman, Nkuchia M M'ikanatha
The evolution of antibiotic resistance is outpacing the speed at which new antibiotics will reach the marketplace. To slow the rate of resistance, people need to engage in antibiotic stewardship, which includes acts to prevent the spread of bacteria and judicious use of antibiotics to treat infections. This study identified the patterns and predictors of antibiotic stewardship behaviors of parents (N = 516) related to their children. The latent class analysis revealed three profiles of parental stewardship, labeled Stewards, Requesters, and Non-Stewards...
October 25, 2017: Health Communication
https://www.readbyqxmd.com/read/29035006/applying-systems-thinking-to-inform-studies-of-wildlife-trade-in-primates
#2
Mary E Blair, Minh D Le, Hoàng M Thạch, Anna Panariello, Ngọc B Vũ, Mark G Birchette, Gautam Sethi, Eleanor J Sterling
Wildlife trade presents a major threat to primate populations, which are in demand from local to international scales for a variety of uses from food and traditional medicine to the exotic pet trade. We argue that an interdisciplinary framework to facilitate integration of socioeconomic, anthropological, and biological data across multiple spatial and temporal scales is essential to guide the study of wildlife trade dynamics and its impacts on primate populations. Here, we present a new way to design research on wildlife trade in primates using a systems thinking framework...
November 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29018307/management-of-citrus-canker-in-argentina-a-success-story
#3
REVIEW
B I Canteros, A M Gochez, R C Moschini
Citrus canker is an important bacterial disease of citrus in several regions of the world. Strains of Xanthomonas citri type-A (Xc-A) group are the primary pathogen where citrus canker occurs. After Xc-A entered the Northeast of Argentina in 1974, the disease spread rapidly from 1977 to 1980 and then slowed down and remained moving at slow pace until 1990 when it became endemic. Citrus canker was detected in Northwest Argentina in 2002. This paper presents the main steps in the fight of the disease and the management strategies that have been used to control citrus canker at this time...
October 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/28992734/book-review-thinking-fast-and-slow-thinking-fast-and-slow-kahneman-daniel-new-york-farrar-strauss-and-giroux-2011-499-pp-isbn-978-0-374-27563-1
#4
Gordon Parker
No abstract text is available yet for this article.
June 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28969326/thinking-fast-and-slow-highlights-from-the-2016-bja-seminar-on-anaesthetic-neurotoxicity-and-neuroplasticity
#5
S G Soriano, L Vutskits, V Jevtovic-Todorovic, H C Hemmings
No abstract text is available yet for this article.
September 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28944555/biological-hierarchies-and-the-nature-of-extinction
#6
Curtis R Congreve, Amanda R Falk, James C Lamsdell
Hierarchy theory recognises that ecological and evolutionary units occur in a nested and interconnected hierarchical system, with cascading effects occurring between hierarchical levels. Different biological disciplines have routinely come into conflict over the primacy of different forcing mechanisms behind evolutionary and ecological change. These disconnects arise partly from differences in perspective (with some researchers favouring ecological forcing mechanisms while others favour developmental/historical mechanisms), as well as differences in the temporal framework in which workers operate...
September 24, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28927863/fast-and-slow-thinking-in-distressing-delusions-a-review-of-the-literature-and-implications-for-targeted-therapy
#7
Thomas Ward, Philippa A Garety
The recent literature on reasoning biases in psychosis and delusions is reviewed. The state-of-the-art knowledge from systematic reviews and meta-analyses on the evidence for jumping to conclusions is briefly summarised, before a fuller discussion of the more recent empirical literature on belief flexibility as applied to delusions. The methodology and evidence in relation to studies of belief flexibility and the Bias Against Disconfirmatory Evidence (BADE) across the delusional continuum will be critically appraised, and implications drawn for improving cognitive therapy...
September 16, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28918863/more-haste-less-speed-a-meta-analysis-of-thinking-latencies-during-planning-in-people-with-psychosis
#8
REVIEW
Andrew J Watson, Eileen M Joyce, Andrew J B Fugard, Verity C Leeson, Thomas R E Barnes, Vyv Huddy
Cognitive impairment is a core feature of psychosis, with slowed processing speed thought to be a prominent impairment in schizophrenia and first-episode psychosis. However, findings from the Stockings of Cambridge (SOC) planning task suggest changes in processing speed associated with the illness may include faster responses in early stages of planning, though findings are inconsistent. This review uses meta-analytic methods to assess thinking times in psychosis across the available literature. Studies were identified by searching PubMed, Web of Science and Google Scholar...
December 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28892141/novel-insights-on-population-and-range-edge-dynamics-using-an-unparalleled-spatiotemporal-record-of-species-invasion
#9
Kristine Grayson, Derek M Johnson
Quantifying the complex spatial dynamics taking place at range edges is critical for understanding future distributions of species, yet very few systems have sufficient data or the spatial resolution to empirically test these dynamics. This paper reviews how data from a large-scale pest management program have provided important contributions to the fields of population dynamics and invasion biology. The invasion of gypsy moth (Lymantria dispar) is well-documented from its introduction near Boston, Massachusetts USA in 1869 to its current extent of over 900,000 km(2) in Eastern North America...
September 11, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28858547/junctional-rhythm-preoperatively-and-during-general-anesthesia-for-oral-and-maxillofacial-surgery
#10
Naotaka Kishimoto, Ikue Kinoshita, Yoshihiro Momota
We report a case of junctional rhythm that occurred both preoperatively and later during a portion of general anesthesia. A 19-year-old woman was scheduled to undergo bilateral sagittal split ramus osteotomy after being diagnosed with a jaw deformity. Preoperative electrocardiography (ECG) revealed a junctional rhythm with a slow heart rate (HR). At 90 minutes after anesthesia induction, local anesthesia with 10 mL of 1% lidocaine and 1:100,000 adrenaline was administered. A junctional rhythm appeared 15 minutes after the local anesthesia...
2017: Anesthesia Progress
https://www.readbyqxmd.com/read/28858480/anodic-cyclization-reactions-and-the-mechanistic-strategies-that-enable-optimization
#11
Ruozhu Feng, Jake A Smith, Kevin D Moeller
Oxidation reactions are powerful tools for synthesis because they allow us to reverse the polarity of electron-rich functional groups, generate highly reactive intermediates, and increase the functionality of molecules. For this reason, oxidation reactions have been and continue to be the subject of intense study. Central to these efforts is the development of mechanism-based strategies that allow us to think about the reactive intermediates that are frequently central to the success of the reactions and the mechanistic pathways that those intermediates trigger...
August 31, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28830236/testing-many-treatments-within-a-single-protocol-over-10%C3%A2-years-at-mrc-clinical-trials-unit-at-ucl-multi-arm-multi-stage-platform-umbrella-and-basket-protocols
#12
Mahesh Kb Parmar, Fay H Cafferty, Matthew R Sydes, Babak Choodari-Oskooei, Ruth E Langley, Louise Brown, Patrick Pj Phillips, Melissa R Spears, Sam Rowley, Richard Kaplan, Nicholas D James, Timothy Maughan, Nicholas Paton, Patrick J Royston
BACKGROUND: There is real need to change how we do some of our clinical trials, as currently the testing and development process is too slow, too costly and too failure-prone - often we find that a new treatment is no better than the current standard. PURPOSE AND METHODS: Much of the focus on the development and testing pathway has been in improving the design of phase I and II trials. In this paper we present examples of new methods for improving the design of phase III trials (and the necessary lead up to them) as they are the most time-consuming and expensive part of the pathway...
August 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28806137/thinking-more-or-feeling-less-explaining-the-foreign-language-effect-on-moral-judgment
#13
Sayuri Hayakawa, David Tannenbaum, Albert Costa, Joanna D Corey, Boaz Keysar
Would you kill one person to save five? People are more willing to accept such utilitarian action when using a foreign language than when using their native language. In six experiments, we investigated why foreign-language use affects moral choice in this way. On the one hand, the difficulty of using a foreign language might slow people down and increase deliberation, amplifying utilitarian considerations of maximizing welfare. On the other hand, use of a foreign language might stunt emotional processing, attenuating considerations of deontological rules, such as the prohibition against killing...
October 2017: Psychological Science
https://www.readbyqxmd.com/read/28801467/minors-moral-psychology-and-the-harm-reduction-debate-the-case-of-tobacco-and-nicotine
#14
Lynn T Kozlowski
Harm reduction debates are important in health policy. Although it has been established that morality affects policy, this article proposes that perspectives from moral psychology help to explain the challenges of developing evidence-based policy on prohibition-only versus tobacco/nicotine harm reduction for minors. Protecting youth from tobacco is critical, especially since tobacco/nicotine products are legal for adults, who usually begin using when young. Although cigarettes and other combustibles are the deadliest tobacco products, other products such as smokeless tobacco and electronic cigarettes, though unsafe, are upward of 90 percent less harmful than cigarettes...
August 11, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28754609/the-drug-delivery-field-at-the-inflection-point-time-to-fight-its-way-out-of-the-egg
#15
Kinam Park
The world is becoming a better place, in part, by breakthrough findings by scientists. In the drug delivery field, many breakthrough formulations have been achieved helping patients deal with various diseases effectively. The recent progress, however, has been slowing down, and many important drug delivery problems have not been resolved. They can be overcome by understanding the causes and finding the remedies. For the last three decades, the field has been overwhelmed by nanotechnology, nanomedicine, and many nano-sized drug delivery systems...
July 25, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28746757/de-extinction-and-barriers-to-the-application-of-new-conservation-tools
#16
Philip J Seddon
Decades of globally coordinated work in conservation have failed to slow the loss of biodiversity. To do better-even if that means nothing more than failing less spectacularly-bolder thinking is necessary. One of the first possible conservation applications of synthetic biology to be debated is the use of genetic tools to resurrect once-extinct species. Since the currency of conservation is biodiversity and the discipline of conservation biology was formed around the prevention of species extinctions, the prospect of reversing extinctions might have been expected to generate unreserved enthusiasm...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28700584/the-selfish-germ
#17
Andrew F Read
Curiosity about the sex life of a wasp led to a new way of thinking and a powerful demonstration that evolutionary science could be predictive. That same approach could help find ways to slow or prevent treatment failures in cancer and infectious diseases.
July 2017: PLoS Biology
https://www.readbyqxmd.com/read/28679327/micro-factors-bringing-the-pharmaceutical-industry-to-a-seismic-shaking-a-qualitative-research
#18
REVIEW
Raphaela Marie Louisa Dierks, Olivier Bruyère, Jean-Yves Reginster
INTRODUCTION: Due to changing macro and micro factors, expiring patents and falling net income, pharmaceutical companies need to rethink their vertical business model. The trend shows cross-sectorial partnerships and consolidation to remain and compete on the market. Areas covered: Quantitative research interviewing a target group of 25 key executives from small, mid and large global pharmaceutical companies rounded with qualitative literature research completing the analysis. Expert commentary: Uncertainty in the industry due to changing external factors i...
June 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28630504/academic-pharmacy-where-is-our-influence
#19
Stefanie P Ferreri, L Brian Cross, Scott D Hanes, Tara Jenkins, Douglas Meyer, Amy Pittenger
Objective. To evaluate the talents of fellows from cohorts 1-10 of the Academic Leadership Fellows Program (ALFP). Methods. This was a descriptive analysis of previously collected ALFP cohort data reflecting the talents using the Clifton StrengthsFinder assessment tool. Data consisted of 295 fellows from the first 10 years of the ALFP program. The Clifton StrengthsFinder talents were aggregated and analyzed to determine talents (strengths) distribution and domain. The aggregate of the four domains were compared among ALFP fellows using a chi-square analysis with an a priori alpha of ...
May 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28624131/studying-arterial-stiffness-using-high-frequency-ultrasound-in-mice-with-alzheimer-disease
#20
Chin-Chia Huang, Hsiang-Fan Cheng, Ben-Peng Zhu, Pei-Yu Chen, Suet Theng Beh, Yu-Min Kuo, Chih-Chung Huang
Alzheimer disease (AD) is an irreversible, progressive brain disorder that causes slow loss of memory and thinking skills, normally leading to death in 3-9 y. The etiology of AD is not fully understood but is widely believed to be induced by the production and deposition of amyloid-β peptide in the brain. Recently, a correlation was discovered between amyloid-β deposition and atherosclerosis in the cerebral arteries of postmortem brains, indicating that amyloid-β promotes atherogenesis and that in turn atherosclerosis promotes brain amyloid-β accumulation...
June 14, 2017: Ultrasound in Medicine & Biology
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