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https://www.readbyqxmd.com/read/28700584/the-selfish-germ
#1
Andrew F Read
Curiosity about the sex life of a wasp led to a new way of thinking and a powerful demonstration that evolutionary science could be predictive. That same approach could help find ways to slow or prevent treatment failures in cancer and infectious diseases.
July 2017: PLoS Biology
https://www.readbyqxmd.com/read/28679327/micro-factors-bringing-the-pharmaceutical-industry-to-a-seismic-shaking-a-qualitative-research
#2
Raphaela Marie Louisa Dierks, Olivier Bruyère, Jean-Yves Reginster
INTRODUCTION: Due to changing macro and micro factors, expiring patents and falling net income, pharmaceutical companies need to rethink their vertical business model. The trend shows cross-sectorial partnerships and consolidation to remain and compete on the market. Areas covered: Quantitative research interviewing a target group of 25 key executives from small, mid and large global pharmaceutical companies rounded with qualitative literature research completing the analysis. Expert commentary: Uncertainty in the industry due to changing external factors i...
July 14, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28630504/academic-pharmacy-where-is-our-influence
#3
Stefanie P Ferreri, L Brian Cross, Scott D Hanes, Tara Jenkins, Douglas Meyer, Amy Pittenger
Objective. To evaluate the talents of fellows from cohorts 1-10 of the Academic Leadership Fellows Program (ALFP). Methods. This was a descriptive analysis of previously collected ALFP cohort data reflecting the talents using the Clifton StrengthsFinder assessment tool. Data consisted of 295 fellows from the first 10 years of the ALFP program. The Clifton StrengthsFinder talents were aggregated and analyzed to determine talents (strengths) distribution and domain. The aggregate of the four domains were compared among ALFP fellows using a chi-square analysis with an a priori alpha of ...
May 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28624131/studying-arterial-stiffness-using-high-frequency-ultrasound-in-mice-with-alzheimer-disease
#4
Chin-Chia Huang, Hsiang-Fan Cheng, Ben-Peng Zhu, Pei-Yu Chen, Suet Theng Beh, Yu-Min Kuo, Chih-Chung Huang
Alzheimer disease (AD) is an irreversible, progressive brain disorder that causes slow loss of memory and thinking skills, normally leading to death in 3-9 y. The etiology of AD is not fully understood but is widely believed to be induced by the production and deposition of amyloid-β peptide in the brain. Recently, a correlation was discovered between amyloid-β deposition and atherosclerosis in the cerebral arteries of postmortem brains, indicating that amyloid-β promotes atherogenesis and that in turn atherosclerosis promotes brain amyloid-β accumulation...
June 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28617009/-the-feasibility-of-implementing-cognitive-remediation-for-work-in-community-based-psychiatric-rehabilitation-programs-correction-to-mcgurk-et-al-2017
#5
(no author information available yet)
Reports an error in "The feasibility of implementing cognitive remediation for work in community based psychiatric rehabilitation programs" by Susan R. McGurk, Kim T. Mueser, Melanie A. Watkins, Carline M. Dalton and Heather Deutsch (Psychiatric Rehabilitation Journal, 2017[Mar], Vol 40[1], 79-86). In the article, the author order was incorrect due to a printer error. The online version of this article has been corrected. (The following abstract of the original article appeared in record 2017-13255-004.) Objective: Adding cognitive remediation to vocational rehabilitation services improves cognitive and work functioning in people with serious mental illness, but despite interest, the uptake of cognitive programs into community services has been slow...
June 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28601164/how-radiologists-think-understanding-fast-and-slow-thought-processing-and-how-it-can-improve-our-teaching
#6
Anouk van der Gijp, Emily M Webb, David M Naeger
Scholars have identified two distinct ways of thinking. This "Dual Process Theory" distinguishes a fast, nonanalytical way of thinking, called "System 1," and a slow, analytical way of thinking, referred to as "System 2." In radiology, we use both methods when interpreting and reporting images, and both should ideally be emphasized when educating our trainees. This review provides practical tips for improving radiology education, by enhancing System 1 and System 2 thinking among our trainees.
June 2017: Academic Radiology
https://www.readbyqxmd.com/read/28574982/mmtf-an-efficient-file-format-for-the-transmission-visualization-and-analysis-of-macromolecular-structures
#7
Anthony R Bradley, Alexander S Rose, Antonín Pavelka, Yana Valasatava, Jose M Duarte, Andreas Prlić, Peter W Rose
Recent advances in experimental techniques have led to a rapid growth in complexity, size, and number of macromolecular structures that are made available through the Protein Data Bank. This creates a challenge for macromolecular visualization and analysis. Macromolecular structure files, such as PDB or PDBx/mmCIF files can be slow to transfer, parse, and hard to incorporate into third-party software tools. Here, we present a new binary and compressed data representation, the MacroMolecular Transmission Format, MMTF, as well as software implementations in several languages that have been developed around it, which address these issues...
June 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28570572/optimal-costs-of-hiv-pre-exposure-prophylaxis-for-men-who-have-sex-with-men
#8
Jennie McKenney, Anders Chen, Karen W Hoover, Jane Kelly, David Dowdy, Parastu Sharifi, Patrick S Sullivan, Eli S Rosenberg
INTRODUCTION: Men who have sex with men (MSM) are disproportionately affected by HIV due to their increased risk of infection. Oral pre-exposure prophylaxis (PrEP) is a highly effictive HIV-prevention strategy for MSM. Despite evidence of its effectiveness, PrEP uptake in the United States has been slow, in part due to its cost. As jurisdictions and health organizations begin to think about PrEP scale-up, the high cost to society needs to be understood. METHODS: We modified a previously-described decision-analysis model to estimate the cost per quality-adjusted life-year (QALY) gained, over a 1-year duration of PrEP intervention and lifetime time horizon...
2017: PloS One
https://www.readbyqxmd.com/read/28541738/book-review-thinking-fast-and-slow-thinking-fast-and-slow-kahneman-daniel-new-york-farrar-strauss-and-giroux-2011-499-pp-isbn-978-0-374-27563-1
#9
Gordon Parker
No abstract text is available yet for this article.
June 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28530073/-red-herring-complaints-in-an-eighteen-years-old-female-with-a-hydatid-cyst-of-the-lung
#10
Nasser Nadim
Brain and eye hydatid cysts are early symptomatic, as opposed to those developing in other organs, including lungs, where they remain asymptomatic through adolescence, even to adulthood, due to their slow growth. Hence, discovering that patients have lung hydatid cyst occurs, frequently, during random chest imaging. Up to thirty percent of pulmonary echinococcal cysts may rupture spontaneously, after chest or abdominal trauma. The main lung hydatidosis complaints, such as dyspnea and chest pain, are caused by the reduction of the functional area of the lung, expectoration of the tapeworm cystoides into the bronchial tree, or by compression of surrounding structures...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28522984/applicability-of-the-compensatory-encoding-model-in-foreign-language-reading-an-investigation-with-chinese-college-english-language-learners
#11
Feifei Han
While some first language (L1) reading models suggest that inefficient word recognition and small working memory tend to inhibit higher-level comprehension processes; the Compensatory Encoding Model maintains that slow word recognition and small working memory do not normally hinder reading comprehension, as readers are able to operate metacognitive strategies to compensate for inefficient word recognition and working memory limitation as long as readers process a reading task without time constraint. Although empirical evidence is accumulated for support of the Compensatory Encoding Model in L1 reading, there is lack of research for testing of the Compensatory Encoding Model in foreign language (FL) reading...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28514530/curious-thoughtful-and-affirmative-young-children-s-meanings-of-participation-in-healthcare-situations-when-using-an-interactive-communication-tool
#12
Anna Stålberg, Anette Sandberg, Thomas Larsson, Imelda Coyne, Maja Söderbäck
AIM: to describe young children's demonstrated participation in healthcare situations while using an interactive communication tool. BACKGROUND: participation is a multidimensional concept influenced by situational and contextual issues. In child participation, verbal and non-verbal communicative expressions are of interest, as both demonstrate the child's perspective. Children have a right to participate in all situations that matter to them, for instance healthcare situations...
May 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28500984/the-need-for-academic-electronic-health-record-systems-in-nurse-education
#13
Joohyun Chung, Insook Cho
The nursing profession has been slow to incorporate information technology into formal nurse education and practice. The aim of this study was to identify the use of academic electronic health record systems in nurse education and to determine student and faculty perceptions of academic electronic health record systems in nurse education. A quantitative research design with supportive qualitative research was used to gather information on nursing students' perceptions and nursing faculty's perceptions of academic electronic health record systems in nurse education...
July 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28476160/time-to-re-think-picky-eating-a-relational-approach-to-understanding-picky-eating
#14
Kathryn Walton, Leon Kuczynski, Emma Haycraft, Andrea Breen, Jess Haines
BACKGROUND: Estimates of picky eating are quite high among young children, with 14-50% of parents identifying their preschoolers as picky eaters. Dietary intake and preferences during the preschool years are characterized by slowing growth rates and children developing a sense of autonomy over their feeding and food selection. We argue that the current conceptualization of picky eating defines acts of resistance or expressions of preference (acts of autonomy) by a child as deviant behaviour...
May 5, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28391348/membranous-nephropathy-thinking-through-the-therapeutic-options
#15
Daniel Cattran, Paul Brenchley
Idiopathic membranous nephropathy (IMN) remains the most common cause of the nephrotic syndrome in adults and one of the leading identifiable causes of end-stage kidney disease. Prior to considering the best approach to treatment, three important components need to be considered. First, the natural history of the typical membranous patient today; second, the importance of identifying the causative factors; and third, the integration of the current data on the known autoantibody/antigen systems involved in IMN into the diagnosis and management of the patient...
January 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28386518/outcomes-assessment-in-clinical-trials-of-alzheimer-s-disease-and-its-precursors-readying-for-short-term-and-long-term-clinical-trial-needs
#16
Holly Posner, Rosie Curiel, Chris Edgar, Suzanne Hendrix, Enchi Liu, David A Loewenstein, Glenn Morrison, Leslie Shinobu, Keith Wesnes, Philip D Harvey
An evolving paradigm shift in the diagnostic conceptualization of Alzheimer's disease is reflected in its recently updated diagnostic criteria from the National Institute on Aging-Alzheimer's Association and the International Working Group. Additionally, it is reflected in the increased focus in this field on conducting prevention trials in addition to improving cognition and function in people with dementia. These developments are making key contributions towards defining new regulatory thinking around Alzheimer's disease treatment earlier in the disease continuum...
January 2017: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/28368181/the-feasibility-of-implementing-cognitive-remediation-for-work-in-community-based-psychiatric-rehabilitation-programs
#17
Susan R McGurk, Kim T Mueser, Melanie A Watkins, Carline M Dalton, Heather Deutsch
OBJECTIVE: Adding cognitive remediation to vocational rehabilitation services improves cognitive and work functioning in people with serious mental illness, but despite interest, the uptake of cognitive programs into community services has been slow. This study evaluated the feasibility of implementing an empirically supported cognitive remediation program in routine rehabilitation services at 2 sites. METHOD: The Thinking Skills for Work (TSW) program was adapted for implementation at 2 sites of a large psychiatric rehabilitation agency providing prevocational services, but not community-based vocational services, which were provided off-site...
March 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28318285/reading-through-the-life-span-individual-differences-in-psycholinguistic-effects
#18
Rob A I Davies, Ruth Arnell, Julia M H Birchenough, Debbie Grimmond, Sam Houlson
The effects of psycholinguistic variables are critical to the evaluation of theories about the cognitive reading system. However, reading research has tended to focus on the impact of key variables on average performance. We report the first investigation examining variation in psycholinguistic effects across the life span, from childhood into old age. We analyzed the performance of a sample of 535 readers, aged 8-83 years in lexical decision and pronunciation tasks. Our findings show that the effects on reading of two key variables, frequency and AoA, decrease in size with increasing age over the life span...
March 20, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28287669/work-life-balance-slow-down-move-and-think
#19
EDITORIAL
Mona Shattell
No abstract text is available yet for this article.
March 1, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28285024/shorter-telomere-length-in-people-with-schizophrenia-a-preliminary-study-from-australia
#20
Cherrie Galletly, Varinderpal S Dhillon, Dennis Liu, Ryan P Balzan, Lisa A Hahn, Michael F Fenech
Schizophrenia is a complex mental illness affecting the normal functioning of the brain, interfering with the ability to think, feel and act. It can be conceptualised as a syndrome of accelerated ageing, with early onset of cardiovascular disease and high rates of premature mortality. Telomere attrition increases with oxidative stress and is considered a biomarker of ageing. Previous studies have assessed abnormalities in telomere length in schizophrenia, but the results are inconsistent. The present study used a case-control design to assess whether people with schizophrenia have shortened telomeres, indicative of accelerated ageing...
March 8, 2017: Schizophrenia Research
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