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https://www.readbyqxmd.com/read/29028054/extended-9-7%C3%A2-%C3%A2-nm-tuning-range-in-a-mopa-system-with-a-tunable-dual-grating-y-branch-laser
#1
Mahmoud Tawfieq, André Müller, Jörg Fricke, Pietro Della Casa, Peter Ressel, David Feise, Bernd Sumpf, Günther Tränkle
In this Letter, we present a tunable Y-branch hybrid master oscillator power amplifier (MOPA) with 5.5 W output power, emitting between 973.7 and 983.4 nm. The MO is a monolithic Y-branch distributed Bragg reflector (DBR) diode laser, which is collimated and coupled into a tapered amplifier using cylindrical microlenses in a compact 25  mm×25  mm conduction cooled laser package. The wavelength spacing between the two laser branches is 2.2 nm. Each branch can be electrically tuned by up to 7.5 nm of quasi-continuous wavelength tuning, which in combination covers up to 9...
October 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29028049/open-cavity-fiber-laser-with-distributed-feedback-based-on-externally-or-self-induced-dynamic-gratings
#2
Ivan A Lobach, Roman V Drobyshev, Andrei A Fotiadi, Evgeniy V Podivilov, Sergey I Kablukov, Sergey A Babin
Dynamic population inversion gratings induced in an active medium by counter-propagating optical fields may have a reverse effect on writing laser radiation via feedback they provide. In this Letter we report, to the best of our knowledge, on the first demonstration of an open-cavity fiber laser in which the distributed feedback is provided by a dynamic grating "written" in a Yb-doped active fiber, either by an external source or self-induced via a weak (∼0.1%) reflection from an angle-cleaved fiber end. It has been shown that meters-long dynamic grating is formed with a narrow bandwidth (<50  MHz) and a relatively high-reflection coefficient (>7%) securing single-frequency operation, but the subsequent hole-burning effects accompanied by new grating formation lead to the switching from one longitudinal mode to another...
October 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29022425/biologics-in-pediatric-psoriasis-efficacy-and-safety
#3
Sunil Dogra, Rahul Mahajan
Introduction Childhood psoriasis is a special situation that is a management challenge for the treating dermatologist. As is the situation with traditional systemic agents, which are commonly used in managing severe psoriasis in children, the biologics are being increasingly used in the recalcitrant disease despite limited data on long term safety. Areas covered - We performed an extensive literature search to collect evidence-based data on the use of biologics in pediatric psoriasis. The relevant literature published from 2000 to September 2017 was obtained from PubMed, using the MeSH words 'biologics', 'biologic response modifiers' or 'treatment of pediatric/childhood psoriasis'...
October 12, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28957178/dense-electro-optic-frequency-comb-generated-by-two-stage-modulation-for-dual-comb-spectroscopy
#4
Shuai Wang, Xinyu Fan, Bingxin Xu, Zuyuan He
An electro-optic frequency comb enables frequency-agile comb-based spectroscopy without using sophisticated phase-locking electronics. Nevertheless, dense electro-optic frequency combs over broad spans have yet to be developed. In this Letter, we propose a straightforward and efficient method for electro-optic frequency comb generation with a small line spacing and a large span. This method is based on two-stage modulation: generating an 18 GHz line-spacing comb at the first stage and a 250 MHz line-spacing comb at the second stage...
October 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28957068/ultra-wideband-ge-rich-silicon-germanium-integrated-mach-zehnder-interferometer-for-mid-infrared-spectroscopy
#5
Vladyslav Vakarin, Joan Manel Ramírez, Jacopo Frigerio, Andrea Ballabio, Xavier Le Roux, Qiankun Liu, David Bouville, Laurent Vivien, Giovanni Isella, Delphine Marris-Morini
This Letter explores the use of Ge-rich Si0.2Ge0.8 waveguides on graded Si1-xGex substrate for the demonstration of ultra-wideband photonic integrated circuits in the mid-infrared (mid-IR) wavelength range. We designed, fabricated, and characterized broadband Mach-Zehnder interferometers fully covering a range of 3 μm in the mid-IR band. The fabricated devices operate indistinctly in quasi-TE and quasi-TM polarizations, and have an extinction ratio higher than 10 dB over the entire operating wavelength range...
September 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28949731/mass-and-moment-of-inertia-govern-the-transition-in-the-dynamics-and-wakes-of-freely-rising-and-falling-cylinders
#6
Varghese Mathai, Xiaojue Zhu, Chao Sun, Detlef Lohse
In this Letter, we study the motion and wake patterns of freely rising and falling cylinders in quiescent fluid. We show that the amplitude of oscillation and the overall system dynamics are intricately linked to two parameters: the particle's mass density relative to the fluid m^{*}≡ρ_{p}/ρ_{f} and its relative moment of inertia I^{*}≡I_{p}/I_{f}. This supersedes the current understanding that a critical mass density (m^{*}≈0.54) alone triggers the sudden onset of vigorous vibrations. Using over 144 combinations of m^{*} and I^{*}, we comprehensively map out the parameter space covering very heavy (m^{*}>10) to very buoyant (m^{*}<0...
August 4, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28949622/adiabatic-theorem-for-quantum-spin-systems
#7
S Bachmann, W De Roeck, M Fraas
The first proof of the quantum adiabatic theorem was given as early as 1928. Today, this theorem is increasingly applied in a many-body context, e.g., in quantum annealing and in studies of topological properties of matter. In this setup, the rate of variation ϵ of local terms is indeed small compared to the gap, but the rate of variation of the total, extensive Hamiltonian, is not. Therefore, applications to many-body systems are not covered by the proofs and arguments in the literature. In this Letter, we prove a version of the adiabatic theorem for gapped ground states of interacting quantum spin systems, under assumptions that remain valid in the thermodynamic limit...
August 11, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28947237/neuropsychological-effects-of-occupational-exposure-to-polychlorinated-biphenyls
#8
B Fimm, W Sturm, A Esser, T Schettgen, K Willmes, J Lang, P M Gaum, T Kraus
In the context of a health surveillance program for former PCB-exposed workers of a transformer and capacitor recycling company in Germany, their family members, employees of surrounding companies and area residents a broad range of cognitive functions covering attention, executive processing, reasoning, memory and motor performance was examined. The study aimed at identifying potential adverse effects of PCB load on cognitive functions. Detailed analysis of PCB burden of the participants revealed rather high correlations of lower and higher chlorinated as well as dioxin-like PCBs...
September 22, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28937548/a-follow-up-study-of-electroconvulsive-therapy-in-children-and-adolescents
#9
Shanti Mitchell, Ehmer Hassan, Neera Ghaziuddin
OBJECTIVES: Electroconvulsive therapy (ECT) is an effective and a safe treatment for several severe psychiatric disorders across the age span. However, its use remains controversial and highly stigmatized especially among patients under 18 years. In this study, we examined current symptoms, attitudes, perception, and functioning of patients treated with ECT when they were less than 18 years old. METHODS: Participants had received ECT before age 18, between 1989 and 2015, at a tertiary medical center...
September 20, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28769775/measuring-mental-workload-with-eeg-fnirs
#10
Haleh Aghajani, Marc Garbey, Ahmet Omurtag
We studied the capability of a Hybrid functional neuroimaging technique to quantify human mental workload (MWL). We have used electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) as imaging modalities with 17 healthy subjects performing the letter n-back task, a standard experimental paradigm related to working memory (WM). The level of MWL was parametrically changed by variation of n from 0 to 3. Nineteen EEG channels were covering the whole-head and 19 fNIRS channels were located on the forehead to cover the most dominant brain region involved in WM...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28764565/fluocinolone-acetonide-for-the-treatment-of-diabetic-macular-edema
#11
Daniele Veritti, Valentina Sarao, Laura Diplotti, Francesco Samassa, Paolo Lanzetta
Fluocinolone acetonide intravitreal implant is a non-erodible implant approved for the treatment of diabetic macular edema (DME) insufficiently responsive to available therapies. Areas covered: The injectable intravitreal implant releases fluocinolone acetonide at an average rate of 0.2 µg/day for at least 36 months. The two pooled pivotal FAME trials showed that, in patients with DME previously treated with laser photocoagulation, fluocinolone acetonide intravitreal implant was more beneficial than sham injection when looking at the proportion of patients with an improvement from baseline in visual acuity of more than 15 letters at 24 months and at 36 months...
October 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28753364/novel-cosmic-ray-electron-and-positron-constraints-on-mev-dark-matter-particles
#12
Mathieu Boudaud, Julien Lavalle, Pierre Salati
MeV dark matter (DM) particles annihilating or decaying to electron-positron pairs cannot, in principle, be observed via local cosmic-ray (CR) measurements because of the shielding solar magnetic field. In this Letter, we take advantage of spacecraft Voyager 1's capacity for detecting interstellar CRs since it crossed the heliopause in 2012. This opens up a new avenue to probe DM in the sub-GeV energy/mass range that we exploit here for the first time. From a complete description of the transport of electrons and positrons at low energy, we derive predictions for both the secondary astrophysical background and the pair production mechanisms relevant to DM annihilation or decay down to the MeV mass range...
July 14, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28740826/epicog-sch-a-brief-battery-to-screen-cognitive-impact-of-schizophrenia-in-stable-outpatients
#13
Silvia Zaragoza Domingo, Julio Bobes, Maria-Paz García-Portilla, Claudia Morralla
Brief batteries in schizophrenia, are needed to screen for the cognitive impact of schizophrenia. We aimed to validate and co-norm the Epidemiological Study of Cognitive Impairment in Schizophrenia (EPICOG-SCH) derived brief cognitive battery. A cross-sectional outpatient evaluation was conducted of six-hundred-seventy-two patients recruited from 234 centers. The brief battery included well-known subtests available worldwide that cover cognitive domains related to functional outcomes: WAIS-III-Letter-Number-Sequencing-LNS, Category Fluency Test-CFT, Logical-Memory Immediate Recall-LM, and Digit-Symbol-Coding-DSC...
June 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28728603/the-effect-of-using-social-pressure-in-cover-letters-to-improve-retention-in-a-longitudinal-health-study-an-embedded-randomised-controlled-retention-trial
#14
Sarah Cotterill, Kelly Howells, Sarah Rhodes, Peter Bower
BACKGROUND: Retention of participants in cohort studies is important for validity. One way to promote retention is by sending a persuasive cover letter with surveys. The study aimed to compare the effectiveness of a covering letter containing social pressure with a standard covering letter on retention in a health cohort study. Social pressure involves persuading people to behave in a certain way by the promise that their actions will be made know to others. We implemented a mild form of social pressure, where the recipient was told that information about whether they responded to the current survey would be noted by the research team and printed on future correspondence from the research team to the recipient...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28708170/widely-wavelength-tunable-fast-intensity-modulated-light-source-for-biophotonic-applications
#15
Tzu-Feng Huang, Sheng-Hao Tseng, Hsien-Yi Wang, Ming-Che Chan
High modulation depth, fast (megahertz to gigahertz), intensity-modulated light sources of various wavelengths within the 0.7-1.35 μm bio-penetration window are highly desirable for many biophotonic diagnosis systems. In this Letter, we present a novel scheme of a wavelength tunable, ultra-broadband light source which simply consists of a pump laser, a nonlinear fiber, and demodulation circuits. The working wavelength range of the light source is from 0.7 to 1.35 μm which covers a vast part of the bio-penetration window, and its modulation frequencies extends from tens of megahertz to gigahertz...
July 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28614323/graphene-based-plasmonic-modulator-on-a-groove-structured-metasurface
#16
Yulin Wang, Tao Li, Shining Zhu
Graphene holds great potential to provide efficient modulation in optoelectronic integrated circuits due to its excellent tunability in conductivity, and several types of graphene-based photonic modulators have already been demonstrated. In this Letter, a plasmonic modulator was proposed based on a groove-structured metasurface covered by a single-layer graphene sheet, in which a transverse electrical-like mode is accommodated. Our design takes advantage of the field enhancement of the plasmonic mode and overcomes the orientation mismatch between the electrical field of the free surface plasmons and the graphene plane...
June 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28576123/evaluation-of-strategies-for-increasing-response-rates-to-postal-questionnaires-in-quality-control-of-nasal-septal-surgery
#17
Merete T Egeland, Magnus Tarangen, Olga Shiryaeva, Caryl Gay, Liv K Døsen, Rolf Haye
BACKGROUND: Postal questionnaires are often used to assess the results of nasal septoplasty, but response rates vary widely. This study assesses strategies designed to increase the response rate. METHODS: Postoperative questionnaires using visual analogue scales (VAS) for nasal obstruction were mailed to 160 consecutive patients alternately allocated to one of two groups. Group A received the questionnaire in the usual manner and group B received a modified cover letter with hand-written name and signature and a hand-stamped return envelope...
June 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28570829/therapeutic-hypothermia-for-asphyxial-out-of-hospital-cardiac-arrest-due-to-drowning-a-systematic-review-of-case-series-and-case-reports
#18
Kai-Fung Kevin Suen, Reynold Leung, Ling-Pong Leung
The objective of this review was to summarize published evidence of the effectiveness of therapeutic hypothermia in patients with drowning-associated asphyxial out-of-hospital cardiac arrest (OHCA) and to explore any preliminary favorable factors in the management of therapeutic hypothermia to improve survival and neurological outcome. Drowning may result in asphyxial OHCA or hypothermic OHCA, but the former does not provide any potential neuroprotective effect as the latter may do. Electronic literature searches of Ovid Medline, Embase, Cochrane Library, and Scopus were performed for all years from inception to July 2016...
June 1, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28514492/ordering-by-the-numbers-in-anatomy-and-by-letters-too
#19
Paul E Neumann, Robert Baud, Pierre Sprumont
Here, new rules of Latin anatomical nomenclature are proposed to deal with cases not covered by existing or other recommended rules. Determiners (e.g., numerals, letters, alphanumeric strings, and Latin names of Greek letters) should follow the noun they specify or limit, just as it is recommended that adjectives should follow the noun they modify. In general, Roman numerals, Latin letters, and Latin names of Greek letters are preferable to Arabic numerals and Greek letters in Latin anatomical terms. It is also noted that the word typus (type) appears to be superfluous and unnecessary in the Latin anatomical nomenclature...
May 17, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28472981/infectious-diseases-of-poverty-the-first-five-years
#20
EDITORIAL
Wei Wang, Jin Chen, Hui-Feng Sheng, Na-Na Wang, Pin Yang, Xiao-Nong Zhou, Robert Bergquist
Although the focus in the area of health research may be shifting from infectious to non-communicable diseases, the infectious diseases of poverty remain a major burden of disease of global health concern. A global platform to communicate and share the research on these diseases is needed to facilitate the translation of knowledge into effective approaches and tools for their elimination. Based on the "One health, One world" mission, a new, open-access journal, Infectious Diseases of Poverty (IDP), was launched by BioMed Central in partnership with the National Institute of Parasitic Diseases (NIPD), Chinese Center for Disease Control and Prevention (China CDC) on October 25, 2012...
May 4, 2017: Infectious Diseases of Poverty
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