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https://www.readbyqxmd.com/read/29899968/gray-bananas-and-a-red-letter-a-from-synesthetic-sensation-to-memory-colors
#1
Franziska Weiss, Mark W Greenlee, Gregor Volberg
Grapheme-color synesthesia is a condition in which objectively achromatic graphemes induce concurrent color experiences. While it was long thought that the colors emerge during perception, there is growing support for the view that colors are integral to synesthetes' cognitive representations of graphemes. In this work, we review evidence for two opposing theories positing either a perceptual or cognitive origin of concurrent colors: the cross-activation theory and the conceptual-mediation model. The review covers results on inducer and concurrent color processing as well as findings concerning the brain structure and grapheme-color mappings in synesthetes and trained mappings in nonsynesthetes...
May 2018: I-Perception
https://www.readbyqxmd.com/read/29851981/ten-simple-rules-for-writing-a-cover-letter-to-accompany-a-job-application-for-an-academic-position
#2
EDITORIAL
Lubomir Tomaska, Jozef Nosek
No abstract text is available yet for this article.
May 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29776672/half-dose-photodynamic-therapy-versus-high-density-subthreshold-micropulse-laser-treatment-in-patients-with-chronic-central-serous-chorioretinopathy-the-place-trial
#3
Elon H C van Dijk, Sascha Fauser, Myrte B Breukink, Rocio Blanco-Garavito, Joannes M M Groenewoud, Jan E E Keunen, Petrus J H Peters, Greet Dijkman, Eric H Souied, Robert E MacLaren, Giuseppe Querques, Susan M Downes, Carel B Hoyng, Camiel J F Boon
PURPOSE: To compare the anatomic and functional efficacy and safety of half-dose photodynamic therapy (PDT) versus high-density subthreshold micropulse laser (HSML) treatment in patients with chronic central serous chorioretinopathy (cCSC). DESIGN: Open-label, multicenter, randomized controlled clinical trial. PARTICIPANTS: Patients with cCSC whose disease had to be confirmed by both clinical characteristics and findings on multimodal imaging...
May 15, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29750373/current-state-of-art-of-str-sequencing-in-forensic-genetics
#4
REVIEW
Antonio Alonso, Pedro A Barrio, Petra Müller, Steffi Köcher, Burkhard Berger, Pablo Martin, Martin Bodner, Sascha Willuweit, Walther Parson, Lutz Roewer, Bruce Budowle
The current state of validation and implementation strategies of MPS technology for the analysis of STR markers for forensic genetics use is described, covering the topics of the current catalogue of commercial MPS-STR panels, leading MPS-platforms, and MPS-STR data analysis tools. In addition, the developmental and internal validation studies carried out to date to evaluate reliability, sensitivity, mixture analysis, concordance, and the ability to analyze challenged samples are summarized. The results of various MPS-STR population studies that showed a large number of new STR sequence variants that increase the power of discrimination in several forensically-relevant loci are also presented...
May 11, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29747381/artificially-expanded-genetic-information-systems-for-new-aptamer-technologies
#5
REVIEW
Elisa Biondi, Steven A Benner
Directed evolution was first applied to diverse libraries of DNA and RNA molecules a quarter century ago in the hope of gaining technology that would allow the creation of receptors, ligands, and catalysts on demand. Despite isolated successes, the outputs of this technology have been somewhat disappointing, perhaps because the four building blocks of standard DNA and RNA have too little functionality to have versatile binding properties, and offer too little information density to fold unambiguously. This review covers the recent literature that seeks to create an improved platform to support laboratory Darwinism, one based on an artificially expanded genetic information system (AEGIS) that adds independently replicating nucleotide “letters” to the evolving “alphabet”...
May 9, 2018: Biomedicines
https://www.readbyqxmd.com/read/29694094/coherent-structures-and-spectral-energy-transfer-in-turbulent-plasma-a-space-filter-approach
#6
E Camporeale, L Sorriso-Valvo, F Califano, A Retinò
Plasma turbulence at scales of the order of the ion inertial length is mediated by several mechanisms, including linear wave damping, magnetic reconnection, the formation and dissipation of thin current sheets, and stochastic heating. It is now understood that the presence of localized coherent structures enhances the dissipation channels and the kinetic features of the plasma. However, no formal way of quantifying the relationship between scale-to-scale energy transfer and the presence of spatial structures has been presented so far...
March 23, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29580552/evidence-for-dna-sequence-encoding-of-an-accessible-nucleosomal-array-across-vertebrates
#7
Frédéric G Brunet, Benjamin Audit, Guénola Drillon, Françoise Argoul, Jean-Nicolas Volff, Alain Arneodo
Nucleosome-depleted regions around which nucleosomes order following the "statistical" positioning scenario were recently shown to be encoded in the DNA sequence in human. This intrinsic nucleosomal ordering strongly correlates with oscillations in the local GC content as well as with the interspecies and intraspecies mutation profiles, revealing the existence of both positive and negative selection. In this letter, we show that these predicted nucleosome inhibitory energy barriers (NIEBs) with compacted neighboring nucleosomes are indeed ubiquitous to all vertebrates tested...
May 22, 2018: Biophysical Journal
https://www.readbyqxmd.com/read/29570338/1-2-e-2-h-conductance-plateau-without-1d-chiral-majorana-fermions
#8
Wenjie Ji, Xiao-Gang Wen
We address the question about the origin of the 1/2(e^{2}/h) conductance plateau observed in a recent experiment on an integer quantum Hall (IQH) film covered by a superconducting (SC) film. Since one-dimensional (1D) chiral Majorana fermions on the edge of the above device can give rise to the half quantized plateau, such a plateau is regarded as conclusive evidence for the chiral Majorana fermions. However, in this Letter we give another mechanism for the 1/2(e^{2}/h) conductance plateau. We find the 1/2(e^{2}/h) conductance plateau to be a general feature of a good electric contact between the IQH film and the SC film, and cannot distinguish the existence or the nonexistence of 1D chiral Majorana fermions...
March 9, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29431599/lithuanian-dentists-knowledge-attitudes-and-clinical-practices-regarding-obstructive-sleep-apnea-a-nationwide-cross-sectional-study
#9
Laurynas Jokubauskas, Gaivilė Pileičikienė, Gediminas Žekonis, Aušra Baltrušaitytė
OBJECTIVE: To investigate the knowledge, attitudes toward, and aspects of clinical practice regarding obstructive sleep apnea (OSA) among Lithuanian dentists. METHODS: A cross-sectional study was carried out during the period from December 2016 to March 2017. A survey instrument was designed and pilot tested prior to full-scale administration. Self-administered questionnaires, including a cover letter, were distributed to 550 dentists during continuing dental education programs...
February 12, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29422026/evaluation-of-a-population-level-strategy-to-promote-tobacco-treatment-use-among-insured-smokers-a-pragmatic-randomized-trial
#10
Jennifer B McClure, Melissa L Anderson
BACKGROUND: Most smokers do not use evidence-based smoking cessation treatment. Increasing utilization of these services is an important public health goal. Health care systems and insurers are well positioned to support this goal within their patient populations. We tested whether a brief, mail-based intervention increased utilization of tobacco cessation services among insured smokers. METHODS: Adult smokers were identified via automated health plan data and randomized to one of five treatment arms (n = 4767)...
February 8, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29387632/i-performed-experiments-and-i-have-results-wow-and-now
#11
EDITORIAL
Johnny Padulo, Andrea De Giorgio, Francesco Oliva, Antonio Frizziero, Nicola Maffulli
Writing a scientific article is not an easy task, but it is definitely a great satisfaction to be able to conclude and publish it. Indeed, each publication is a service we make to the entire scientific community and to the advancement of science even before our personal career. There is and there will not be a final book/article for writing a scientific paper. Therefore, some knowledge is a decisive factor to increase the chances of our work being accepted by a specialized scientific journal. The purpose of this editorial is to trace an ideal path, based on our personal experience, useful to properly structure a scientific article, from bibliographic research to cover letter...
July 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/29332496/double-jeopardy-insurance-animal-harm-and-domestic-violence
#12
Tania Signal, Nik Taylor, Karena J Burke, Luke Brownlow
Although the role of companion animals within the dynamic of domestic violence (DV) is increasingly recognized, the overlap of animal harm and insurance discrimination for victims/survivors of DV has not been considered. Prompted by a case study presented in a National Link Coalition LINK-Letter, this research note examines "Pet Insurance" policies available in Australia and whether nonaccidental injury caused by an intimate partner would be covered. We discuss the implications of exclusion criteria for victims/survivors of DV, shelters providing places for animals within a DV dynamic, and, more broadly, for cross- or mandatory-reporting (of animal harm) initiatives...
May 2018: Violence Against Women
https://www.readbyqxmd.com/read/29202616/series-practical-guidance-to-qualitative-research-part-4-trustworthiness-and-publishing
#13
Irene Korstjens, Albine Moser
In the course of our supervisory work over the years we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called frequently asked questions (FAQs). This series of four articles intends to provide novice researchers with practical guidance for conducting high-quality qualitative research in primary care. By 'novice' we mean Master's students and junior researchers, as well as experienced quantitative researchers who are engaging in qualitative research for the first time...
December 2018: European Journal of General Practice
https://www.readbyqxmd.com/read/29197362/evidence-for-the-need-for-vision-screening-of-school-children-in-turkey
#14
Serap Azizoğlu, Sheila G Crewther, Funda Şerefhan, Ayla Barutchu, Sinan Göker, Barbara M Junghans
BACKGROUND: In many countries, access to general health and eye care is related to an individual's socioeconomic status (SES). We aimed to examine the prevalence of oculo-visual disorders in children in Istanbul Turkey, drawn from schools at SES extremes but geographically nearby. METHODS: Three school-based vision screenings (presenting distance visual acuity, cover test, eye assessment history, colour vision, gross stereopsis and non-cycloplegic autorefraction) were conducted on 81% of a potential 1014 primary-school children aged 4-10 years from two private (high SES) schools and a nearby government (low SES) school in central Istanbul...
December 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29167106/use-of-a-primary-care-online-consultation-system-by-whom-when-and-why-evaluation-of-a-pilot-observational-study-in-36-general-practices-in-south-west-england
#15
Hannah B Edwards, Elsa Marques, William Hollingworth, Jeremy Horwood, Michelle Farr, Elly Bernard, Chris Salisbury, Kate Northstone
OBJECTIVES: Evaluation of a pilot study of an online consultation system in primary care. We describe who used the system, when and why, and the National Health Service costs associated with its use. DESIGN: 15-month observational study. SETTING: Primary care practices in South West England. RESULTS: 36 General practices covering 396 828 patients took part in the pilot. The online consultation website was viewed 35 981 times over the pilot period (mean 9...
November 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29097353/-a-phenomenal-person-and-doctor-thank-you-letters-to-medical-care-providers
#16
Talya Miron-Shatz, Stefan Becker, Franklin Zaromb, Alexander Mertens, Avi Tsafrir
BACKGROUND: Thank you letters to physicians and medical facilities are an untapped resource, providing an invaluable glimpse into what patients notice and appreciate in their care. OBJECTIVE: The aim of this study was to analyze such thank you letters as posted on the Web by medical institutions to find what patients and families consider to be good care. In an age of patient-centered care, it is pivotal to see what metrics patients and families apply when assessing their care and whether they grasp specific versus general qualities in their care...
November 2, 2017: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/29080875/-application-of-molecular-descriptors-for-recognition-of-phosphorylation-sites-in-amino-acid-sequences
#17
D A Karasev, P I Savosina, B N Sobolev, D A Filimonov, A A Lagunin
Recognition of the phosphorylation sites in proteins is required for reconstruction of regulatory processes in living systems. This task is complicated because the phosphorylation motifs in amino acid sequences are considerably degenerated. To improve the prediction efficacy researchers often use additional descriptors, which should reflect physicochemical features of site-surrounding regions. We have evaluated the reasonability of this approach by applying molecular descriptors (MNA) for structural presentation of the peptide segments...
October 2017: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/29058857/california-dentists-opinions-of-the-interface-between-oral-and-overall-health
#18
Paul Gavaza, Thomas Rogers, Rashid Mosavin
This cross-sectional study investigated California dentists’ knowledge and opinion of the interface between oral and overall health. A questionnaire and cover letter explaining the purpose of the study were mailed to 1,100 randomly selected California licensed general dentists. The survey measured dentists’ knowledge and opinions of the interface between oral and overall health as well as their recommendations for strengthening this interface. Dentists believed that there was minimal interface between oral and overall health care...
February 2017: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29028054/extended-9-7-nm-tuning-range-in-a-mopa-system-with-a-tunable-dual-grating-y-branch-laser
#19
Mahmoud Tawfieq, André Müller, Jörg Fricke, Pietro Della Casa, Peter Ressel, David Feise, Bernd Sumpf, Günther Tränkle
In this Letter, we present a tunable Y-branch hybrid master oscillator power amplifier (MOPA) with 5.5 W output power, emitting between 973.7 and 983.4 nm. The MO is a monolithic Y-branch distributed Bragg reflector (DBR) diode laser, which is collimated and coupled into a tapered amplifier using cylindrical microlenses in a compact 25  mm×25  mm conduction cooled laser package. The wavelength spacing between the two laser branches is 2.2 nm. Each branch can be electrically tuned by up to 7.5 nm of quasi-continuous wavelength tuning, which in combination covers up to 9...
October 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29028049/open-cavity-fiber-laser-with-distributed-feedback-based-on-externally-or-self-induced-dynamic-gratings
#20
Ivan A Lobach, Roman V Drobyshev, Andrei A Fotiadi, Evgeniy V Podivilov, Sergey I Kablukov, Sergey A Babin
Dynamic population inversion gratings induced in an active medium by counter-propagating optical fields may have a reverse effect on writing laser radiation via feedback they provide. In this Letter we report, to the best of our knowledge, on the first demonstration of an open-cavity fiber laser in which the distributed feedback is provided by a dynamic grating "written" in a Yb-doped active fiber, either by an external source or self-induced via a weak (∼0.1%) reflection from an angle-cleaved fiber end...
October 15, 2017: Optics Letters
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