Jun-Hong Xing, Tian-Ming Niu, Bo-Shi Zou, Gui-Lian Yang, Chun-Wei Shi, Qing-Song Yan, Ming-Jie Sun, Tong Yu, Shu-Min Zhang, Xi-Ze Feng, Shu-Hui Fan, Hai-Bin Huang, Jun-Hong Wang, Ming-Han Li, Yan-Long Jiang, Jian-Zhong Wang, Xin Cao, Nan Wang, Yan Zeng, Jing-Tao Hu, Di Zhang, Wu-Sheng Sun, Wen-Tao Yang, Chun-Feng Wang
BACKGROUND: The gut microbiota is a critical factor in the regulation of host health, but the relationship between the differential resistance of hosts to pathogens and the interaction of gut microbes is not yet clear. Herein, we investigated the potential correlation between the gut microbiota of piglets and their disease resistance using single-cell transcriptomics, 16S amplicon sequencing, metagenomics, and untargeted metabolomics. RESULTS: Porcine epidemic diarrhea virus (PEDV) infection leads to significant changes in the gut microbiota of piglets...
February 5, 2024: Microbiome