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plant-based diet and nitric oxide

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https://www.readbyqxmd.com/read/27836721/the-european-seabass-dicentrarchus-labrax-innate-immunity-and-gut-health-are-modulated-by-dietary-plant-protein-inclusion-and-prebiotic-supplementation
#1
Rita Azeredo, Marina Machado, Eva Kreuz, Sven Wuertz, Aires Oliva-Teles, Paula Enes, Benjamín Costas
Inclusion of prebiotics in aqua feeds, though a costly strategy, has increased as a means to improve growth. Still, its effects on health improvement are not fully disclosed. Regarding their immunestimulatory properties, research has focused on carbohydrates such as fructooligosaccharides and xylooligosaccharides demonstrating their modulatory effects on immune defences in higher vertebrates but few studies have been done on their impact on fish immunity. Replacing fish meal (FM) by plant protein (PP) sources is a current practice in the aquaculture business but their content in antinutrients is still a drawback in terms of gut well-functioning...
November 9, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27567547/protective-effects-of-ursolic-acid-against-hepatotoxicity-and-endothelial-dysfunction-in-mice-with-chronic-high-choline-diet-consumption
#2
Dongyu Li, Daoyuan Ren, Yiyang Luo, Xingbin Yang
This study was designed to investigate the preventive effect of ursolic acid (UA), a plant-based pentacyclic triterpenoid carboxyl acid, against vascular endothelial damage and liver oxidative injury in the mice fed with 3% dietary high choline (HC) water. Mice fed 3% HC water for 8 weeks significantly displayed liver oxidative stress and vascular endothelial dysfunction (p < 0.01). Furthermore, continuous administration of UA at 400 and 800 mg/kg bw in HC-fed mice could significantly inhibit the HC-induced elevation of serum total cholesterol, total triglyceride, low density lipoprotein-cholesterol, endothelin 1 and thromboxane A2 levels as well as alanine aminotransferase and aspartate aminotransferase activities, while the HC-induced decline of serum high density lipoprotein-cholesterol, endothelial nitric oxide synthase, nitric oxide and prostaglandin I2 levels could be markedly elevated following the treatment (p < 0...
October 25, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/26802896/prebiotics-effect-on-immune-and-hepatic-oxidative-status-and-gut-morphology-of-white-sea-bream-diplodus-sargus
#3
Inês Guerreiro, Ana Couto, Marina Machado, Carolina Castro, Pedro Pousão-Ferreira, Aires Oliva-Teles, Paula Enes
The aim of this study was to evaluate the effects of short-chain fructooligosaccharides (scFOS), xylooligosaccharides (XOS) and galactooligosaccharides (GOS) on immune and hepatic oxidative status, and gut morphology of white sea bream juveniles. Four diets were formulated: a control diet with fish meal (FM) and plant feedstuffs (PF) (30FM:70PF) and three test diets similar to the control but supplemented with 1% of scFOS, XOS or GOS. Dietary prebiotic incorporation did not affect total blood cell counts, hematocrit, hemoglobin, red blood indices or differential white blood cell counts...
March 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/24944768/effects-of-plant-based-korean-food-extracts-on-lipopolysaccharide-stimulated-production-of-inflammatory-mediators-in-vitro
#4
Sun Young Lee, Yoo-Sun Kim, Ji Ye Lim, Namsoo Chang, Myung-Hee Kang, Se-Young Oh, He-Jin Lee, Hyesook Kim, Yuri Kim
BACKGROUND/OBJECTIVES: The traditional Korean diet is plant-based and rich in antioxidants. Previous studies have investigated the potential health benefits of individual nutrients of Korean foods. However, the cumulative effects of a Korean diet on inflammation remain poorly understood. Therefore, the aim of this study was to investigate the anti-inflammatory effects of a plant-based Korean diet. MATERIALS/METHODS: Using data from the Fifth Korean National Health and Nutrition Examination Survey, 75 individual plant food items were selected which represent over 1% of the total diet intake of the Korean diet...
June 2014: Nutrition Research and Practice
https://www.readbyqxmd.com/read/20674858/activation-of-trpv1-by-dietary-capsaicin-improves-endothelium-dependent-vasorelaxation-and-prevents-hypertension
#5
Dachun Yang, Zhidan Luo, Shuangtao Ma, Wing Tak Wong, Liqun Ma, Jian Zhong, Hongbo He, Zhigang Zhao, Tingbing Cao, Zhencheng Yan, Daoyan Liu, William J Arendshorst, Yu Huang, Martin Tepel, Zhiming Zhu
Some plant-based diets lower the cardiometabolic risks and prevalence of hypertension. New evidence implies a role for the transient receptor potential vanilloid 1 (TRPV1) cation channel in the pathogenesis of cardiometabolic diseases. Little is known about impact of chronic TRPV1 activation on the regulation of vascular function and blood pressure. Here we report that chronic TRPV1 activation by dietary capsaicin increases the phosphorylation of protein kinase A (PKA) and eNOS and thus production of nitric oxide (NO) in endothelial cells, which is calcium dependent...
August 4, 2010: Cell Metabolism
https://www.readbyqxmd.com/read/20102949/effect-of-intensive-lifestyle-changes-on-endothelial-function-and-on-inflammatory-markers-of-atherosclerosis
#6
Harvinder S Dod, Ravindra Bhardwaj, Venu Sajja, Gerdi Weidner, Gerald R Hobbs, Gregory W Konat, Shanthi Manivannan, Wissam Gharib, Bradford E Warden, Navin C Nanda, Robert J Beto, Dean Ornish, Abnash C Jain
Intensive lifestyle changes have been shown to regress atherosclerosis, improve cardiovascular risk profiles, and decrease angina pectoris and cardiac events. We evaluated the influence of the Multisite Cardiac Lifestyle Intervention Program, an ongoing health insurance-covered lifestyle intervention conducted at our site, on endothelial function and inflammatory markers of atherosclerosis in this pilot study. Twenty-seven participants with coronary artery disease (CAD) and/or risk factors for CAD (nonsmokers, 14 men; mean age 56 years) were enrolled in the experimental group and asked to make changes in diet (10% calories from fat, plant based), engage in moderate exercise (3 hours/week), and practice stress management (1 hour/day)...
February 1, 2010: American Journal of Cardiology
https://www.readbyqxmd.com/read/12489822/cyanidin-3-o-beta-d-glucoside-suppresses-nitric-oxide-production-during-a-zymosan-treatment-in-rats
#7
Takanori Tsuda, Fumihiko Horio, Toshihiko Osawa
Anthocyanins are used for food color, and they are widely distributed in the human diets, suggesting that we ingest considerable amounts of anthocyanins from plant-based daily diets. We have demonstrated that a typical anthocyanin, cyanidin 3-O-beta-D-glucoside (C3G), suppressed the zymosan-induced inflammatory response in rats when it was orally administered. The elevation of the peritoneal exudate NOx, tumor necrosis factor (TNF) alpha interleukin-1beta (IL-1beta), IL-6, and the cytokine-induced neutrophil chemoattractant-1 (CINC-1) concentrations were significantly suppressed by the administration of C3G...
August 2002: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/11545625/dietary-polyunsaturated-fatty-acid-and-antioxidant-modulation-of-vascular-dysfunction-in-the-spontaneously-hypertensive-rat
#8
M Y Abeywardena, R J Head
Two currently available edible oils-olive and canola-and two oil blends of plant origin having different n-3/n-6 polyunsaturated fatty acid (PUFA) ratios were evaluated for their ability to modify vascular dysfunction in the spontaneously hypertensive rat (SHR). Synthetic diets supplemented with test oils (5% w/w) were fed for 12 weeks, and segments of thoracic aorta used to assess vascular function. Vessels from the SHR displayed a spontaneous constrictor response after the inhibition of endothelial cell nitric oxide (NO) with N(omega)-nitro-L-arginine (NOLA)...
August 2001: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/11469396/feeding-a-protective-hydrolysed-casein-diet-to-young-diabetic-prone-bb-rats-affects-oxidation-of-l-u-14c-glutamine-in-islets-and-peyer-s-patches-reduces-abnormally-high-mitotic-activity-in-mesenteric-lymph-nodes-enhances-islet-insulin-and-tends-to-normalize
#9
W J Malaisse, E Olivares, A Laghmich, L Ladrière, A Sener, F W Scott
The present studies were undertaken to examine concomitant diet-induced changes in pancreatic islets and cells of the gut immune system of diabetes-prone BB rats in the period before classic insulitis. Diabetes-prone (BBdp) and control nondiabetes prone (BBc) BB rats were fed for approximately 17 days either a mainly plant-based standard laboratory rodent diet associated with high diabetes frequency, NIH-07 (NIH) or a protective semipurified diet with hydrolyzed casein (HC) as the amino acid source. By about 7 weeks of age, NIH-fed BBdp rats had lower plasma insulin and insulin/glucose ratio, lower insulin content of isolated islets, lower basal levels of NO but higher responsiveness of NO production to IL-1beta in cultured islets, and higher Con A response and biosynthetic activities in mesenteric lymphocytes than control rats fed the same diet...
2000: International Journal of Experimental Diabetes Research
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