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Michael Dattilo, Valérie Biousse, Nancy J Newman
Central retinal artery occlusion (CRAO) is caused by partial or complete occlusion of the central retinal artery, most commonly by an embolus from the ipsilateral carotid artery, aortic arch, or heart, and is the ocular equivalent of an acute cerebral ischemic event. The risk factors for a CRAO and acute cerebral ischemia are very similar, if not identical. Because no current therapeutic intervention has been shown to improve visual outcomes compared with the natural history of CRAO, management of CRAO should be focused on secondary prevention of vascular events, such as cerebral ischemia, myocardial infarction, and cardiovascular death...
February 2017: Neurologic Clinics
Rima M Dafer, John H Pula, Shakeel Chowdhry
Central retinal artery occlusion (CRAO) is a devastating ocular emergency characterized by acute painless visual loss in the ipsilateral eye. We describe the case of acute non-arteritic CRAO associated fusiform internal carotid-ophthalmic artery aneurysm with intraluminal thrombus. Despite the rarity of this condition, we suggest that carotid-ophthalmic artery aneurysm should be included in the differential diagnosis of CRAO.
November 16, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Paul S Page, Alexander C Cambon, Robert F James
BACKGROUND: Intra-arterial thrombolysis (IAT) for the treatment of acute central retinal artery occlusion (CRAO) has demonstrated variable results for improving visual acuity and remains controversial. Despite limited evidence, time from symptom onset to thrombolysis is believed to be an important factor in predicting visual improvement after IAT. METHODS: A comprehensive review of the literature was conducted and individual subject level data were extracted from relevant studies...
September 2016: Interventional Neurology
Hui-Chen Cheng, Ren-Hao Pan, Huan-Jui Yeh, K Robert Lai, May-Yung Yen, Chien-Lung Chan, An-Guor Wang
PURPOSE: To investigate whether daily changes in ambient air pollution were associated with an increased risk of central retinal artery occlusion (CRAO). DESIGN: Retrospective population-based cohort study. PARTICIPANTS: We identified patients newly diagnosed with CRAO between 2001 and 2013 in a representative database of 1 000 000 patients that were randomly selected from all registered beneficiaries of the National Health Insurance program in Taiwan...
October 13, 2016: Ophthalmology
Young Ho Jung, Seong Joon Ahn, Jeong-Ho Hong, Kyu Hyung Park, Moon-Ku Han, Cheolkyu Jung, Se Joon Woo
PURPOSE: To investigate the incidence of neovascularization of the iris (NVI) and clinical features of patients with NVI following acute central retinal artery occlusion (CRAO). METHODS: A retrospective review of 214 consecutive CRAO patients who visited one tertiary hospital between January 2009 and January 2015 was conducted. In total, 110 patients were eligible for this study after excluding patients with arteritic CRAO, a lack of follow-up, iatrogenic CRAO secondary to cosmetic filler injection, or NVI detected before CRAO attack...
October 2016: Korean Journal of Ophthalmology: KJO
Xiao-Jun Wu, Feng Gao, Xu Liu, Qing Zhao
The aim of the present study was to observe the clinical efficacy and safety of recombinant tissue plasminogen activator (rt-PA) combined with compound anisodine in treating central retinal artery occlusion (CRAO). Forty-eight patients diagnosed with CRAO were randomly divided into a treatment group (24 cases) and a control group (24 cases). For the control group, nitroglycerin, 654-2, methazolamide, puerarin and compound anisodine were used for the treatment, along with oxygen, massage and other conventional treatments...
October 2016: Experimental and Therapeutic Medicine
Peter H Tang, Kevin Engel, David Wilkin Parke
Central retinal artery occlusion (CRAO) is an infarction to the retina that results in acute, frequently severe vision loss. Long-term complications such as ocular neovascularization (ONV) can occur and result in neovascular glaucoma and vitreous hemorrhage. Recent studies have explored acute hyperbaric oxygen (HBO) therapy as a promising treatment for CRAO to improve long-term vision potential; however, its effects on CRAO complications have not been well characterized. This study was conducted to better characterize the effects of HBO therapy on complications from CRAO...
September 9, 2016: Ophthalmology and Therapy
Kwan Hyuk Cho, Seong Joon Ahn, Joon Hee Cho, Cheolkyu Jung, Moon-Ku Han, Sang Jun Park, Kyu Hyung Park, Se Joon Woo
PURPOSE: To analyze the characteristics of retinal emboli and their association with vascular reperfusion in retinal artery occlusion (RAO). METHODS: In this retrospective comparative case series, we analyzed emboli in patients with acute central retinal artery occlusion (CRAO) or branch retinal artery occlusion (BRAO) and visible emboli, and analyzed vascular reperfusion in patients with visible emboli causing blockage of perfusion. The patients were divided into emboli "movement" and "no movement" groups and their vascular reperfusion states were compared...
September 1, 2016: Investigative Ophthalmology & Visual Science
Yue Zhou, Wengen Zhu, Changyun Wang
Several studies investigating the role of retinal vascular occlusions, on cerebrovascular diseases (CVD) have been reported, but the results are still inconsistent. We therefore sought to evaluate the relationship between retinal vascular occlusions and CVD.We systematically searched the Cochrane Library, PubMed, and ScienceDirect databases through January 31, 2016 for studies evaluating the effect of retinal vascular occlusions on the risk of CVD. Data were abstracted using predefined criteria, and then pooled by RevMan 5...
June 2016: Medicine (Baltimore)
Hongxia Gong, Qiuying Song, Lanhui Wang
The aim of this study was to investigate the association between central visual impairment and the characteristics of fundus fluorescein angiography (FFA) in patients with central retinal artery occlusion (CRAO). A total of 63 patients were diagnosed with CRAO by FFA. The visual dysfunction was classified into severe, mild and light degrees. Tropicamide was administered for mydriasis. FFA examination was performed using Heidelberg retinal tomography. The associations of age, gender and disease course with CRAO type were analyzed...
June 2016: Experimental and Therapeutic Medicine
John J Chen, Jacqueline A Leavitt, Chengbo Fang, Cynthia S Crowson, Eric L Matteson, Kenneth J Warrington
PURPOSE: To determine the incidence of permanent visual loss from giant cell arteritis (GCA). DESIGN: Retrospective, population-based cohort. PARTICIPANTS: All residents of Olmsted County, Minnesota, diagnosed with GCA between January 1, 1950, and December 31, 2009. METHODS: All cases of GCA were identified using the Rochester Epidemiology Project (REP), which is a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota, residents...
September 2016: Ophthalmology
Nancy E Epstein
BACKGROUND: Postoperative visual loss (POVL) following prone spine surgery occurs in from 0.013% to 1% of cases and is variously attributed to ischemic optic neuropathy (ION: anterior ION or posterior ION [reported in 1.9/10,000 cases: constitutes 89% of all POVL cases], central retinal artery occlusion [CRAO], central retinal vein occlusion [CRVO], cortical blindness [CB], direct compression [horseshoe, prone pillows, and eye protectors Dupaco Opti-Gard]), and acute angle closure glaucoma (AACG)...
2016: Surgical Neurology International
Nancy E Epstein
BACKGROUND: In a prior article, "Perioperative visual loss (POVL) following prone spinal surgery: A review," Epstein documented that postoperative visual loss (POVL) occurs in from 0.013% to 0.2% of spine procedures performed in the prone position. POVL is largely attributed to ischemic optic neuropathy (ION), central retinal artery occlusion (CRAO), cortical blindness (CB), direct compression (prone pillows/horseshoe, eye protectors), and rarely, acute angle closure glaucoma. METHODS: Risk factors for ION include prolonged surgery, extensive fusions, anemia, hypotension, hypovolemia, diabetes, obesity, use of the Wilson frame, male sex, and microvascular pathology...
2016: Surgical Neurology International
Gena Damento, Michael H Chen, Theodore Leng
The authors report the use of optical coherence tomography angiography (OCTA) to determine retinal blood flow in a patient with central retinal artery occlusion (CRAO). Spectral-domain OCTA (SD-OCTA) was performed on an eye with CRAO. En face vascular images were constructed using an optical microangiography algorithm. The retinal vasculature was clearly imaged with high fidelity; areas of perfused retina were identified with exquisite detail. This study supports use of OCTA in diagnosing and monitoring CRAOs...
May 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Lucas T Lenci, Eric K Chin, David R P Almeida
PURPOSE: To report a case of central retinal artery occlusion (CRAO) in a young human immunodeficiency virus (HIV)-infected patient recently started on highly active antiretroviral therapy. METHODS: Case report observation of a 33-year-old HIV-infected patient who developed a CRAO after starting highly active antiretroviral therapy. RESULTS: Elevated triglycerides caused by starting highly active antiretroviral therapy preceded the development of CRAO in an HIV-infected patient...
April 22, 2016: Retinal Cases & Brief Reports
M Govare, T Cornut, C Seguy, M B Rougier, M N Delyfer, J F Korobelnik
No abstract text is available yet for this article.
April 2016: Journal Français D'ophtalmologie
Haoyu Chen, Honghe Xia, Zhiqiao Qiu, Weiqi Chen, Xinjian Chen
PURPOSE: To investigate the relationship between optical coherence tomography (OCT) characteristics at baseline and visual outcome in central retinal artery occlusion (CRAO). METHODS: The medical charts and OCT images of patients with central retinal artery occlusion with follow-up for more than 90 days were reviewed. Optical intensities of inner retinal layers, outer nuclear layers, and photoreceptor/retinal pigment epithelium were measured using Image J software...
October 2016: Retina
José Alberto Lemos, Carla Teixeira, Rui Carvalho, Tiago Fernandes
BACKGROUND: Combined central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) is an uncommon retinal vascular disease which causes sudden visual acuity loss and is associated with poor prognosis and the development of severe complications. We report a very rare case of combined CRAO and CRVO in a patient with factor V Leiden (FVL) mutation (only 3 cases published). To our knowledge, this is the first case of combined CRAO and CRVO treated with hyperbaric oxygen therapy (HBOT)...
September 2015: Case Reports in Ophthalmology
Alessandro Riccardi, Cristina Siniscalchi, Roberto Lerza
BACKGROUND: Ocular emergencies account for 2-3% of all emergency department (ED) visits. Sonographic evaluation of the eye offers a very useful diagnostic tool in the ED. In the ED setting, ocular ultrasound could identify a retinal detachment, or a massive vitreous hemorrhage, and the training for emergency medicine practitioners is quite easy. CASE REPORT: An 84-year-old woman presented to our ED with a painless acute vision loss in her right eye. Immediate bedside emergency ocular ultrasound was performed, and it showed a retrobulbar hyperechoic material, suggestive of an embolus within the central retinal artery...
April 2016: Journal of Emergency Medicine
Seong Joon Ahn, Kyu Hyung Park, Na-Kyung Ryoo, Jeong-Ho Hong, Cheolkyu Jung, Chang-Hwan Yoon, Moon-Ku Han, Se Joon Woo
PURPOSE: To investigate the incidence and risk factors of the no-reflow phenomenon in central retinal artery occlusion (CRAO) patients and to determine its effects on visual and anatomic outcomes. METHODS: In 102 eyes with CRAO in which arterial recanalization was obtained within 1 week from baseline, fluorescein angiography images obtained at baseline and 1 week were retrospectively reviewed. The no-reflow phenomenon in the retina was defined as macular capillary nonperfusion following arterial recanalization on fluorescein angiographs...
2015: PloS One
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