keyword
MENU ▼
Read by QxMD icon Read
search

Melatonin sleep

keyword
https://www.readbyqxmd.com/read/29045623/the-influence-of-circadian-timing-on-olfactory-sensitivity
#1
Rachel S Herz, Eliza Van Reen, David Barker, Cassie J Hilditch, Ashten Bartz, Mary A Carskadon
Olfactory sensitivity has traditionally been viewed as a trait that varies according to individual differences but is not expected to change with one's momentary state. Recent research has begun to challenge this position and time of day has been shown to alter detection levels. Links between obesity and the timing of food intake further raise the issue of whether odor detection may vary as a function of circadian processes. To investigate this question, thirty-seven (21 male) adolescents (M age =13.7 years) took part in a 28-hr forced-desynchrony (FD) protocol with 17...
October 17, 2017: Chemical Senses
https://www.readbyqxmd.com/read/29040758/linking-light-exposure-and-subsequent-sleep-a-field-polysomnography-study-in-humans
#2
Emma J Wams, Tom Woelders, Irene Marring, Laura van Rosmalen, Domien G M Beersma, Marijke C M Gordijn, Roelof A Hut
Study objectives: To determine the effect of light exposure on subsequent sleep characteristics under ambulatory field conditions. Methods: Twenty healthy participants were fitted with ambulatory PSG and wrist-actigraphs to assess light exposure, rest-activity, sleep quality, timing and architecture. Laboratory salivary dim-light melatonin onset (DLMO) was analyzed to determine endogenous circadian phase. Results: Later circadian clock phase was associated with lower intensity (R2=0...
October 11, 2017: Sleep
https://www.readbyqxmd.com/read/29039977/chronic-disruptions-of-circadian-sleep-regulation-induce-specific-proinflammatory-responses-in-the-rat-colon
#3
Lenka Polidarová, Pavel Houdek, Alena Sumová
Exposure to environmental conditions that disturb the daily rhythms has been shown to enhance the proinflammatory responses of immunostimulant-challenged immune system. However, it is not known whether circadian disturbances may stimulate unchallenged immune responses and thus contribute per se to the development of inflammation-related diseases. Our aim was to ascertain an effect of various conditions threatening the behavioral activity/rest cycle regulation, namely aging with or without melatonin, 6 h advance/delay phase shifts in the light/dark cycle repeated with a 2-day frequency and constant light, on expression of immune markers in the rat colon...
October 17, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29035008/average-mid-sleep-time-as-a-proxy-for-circadian-phase
#4
Thomas Kantermann, Helen J Burgess
Assessments of circadian phase using melatonin are laborious. Sleep-time indices allow for less laborious phase calculations, but common indices weakly represent melatonin phase. We show how a single sleep-time assessment can represent melatonin phase by over 60%, improving the use of subjective sleep to mirror objective circadian phase.
October 16, 2017: PsyCh Journal
https://www.readbyqxmd.com/read/29029340/circadian-phase-and-phase-angle-disorders-in-primary-insomnia
#5
Erin E Flynn-Evans, Julia A Shekleton, Belinda Miller, Lawrence J Epstein, Douglas Kirsch, Lauren A Brogna, Liza M Burke, Erin Bremer, Jade M Murray, Philip Gehrman, Shantha M W Rajaratnam, Steven W Lockley
Objectives: We aimed to identify the prevalence of circadian phase and phase angle abnormalities in patients with insomnia. Methods: We conducted a cross-sectional, multicenter study at three sleep laboratories in the United States and Australia. Patients with insomnia and healthy control participants completed a sleep log for seven days. Circadian phase was assessed from salivary Dim Light Melatonin Onset (DLMO) time during a 12-hour laboratory visit. Results: Seventy-nine patients meeting the Research Diagnostic Criteria for Primary, Psychophysiological, Paradoxical, and/or Idiopathic Childhood Insomnia (46F, 35...
October 3, 2017: Sleep
https://www.readbyqxmd.com/read/28992833/non-24-hour-sleep-wake-rhythm-disorder-and-melatonin-secretion-impairment-in-a-patient-with-pineal-cyst
#6
Lorenzo Ferri, Marco Filardi, Monica Moresco, Fabio Pizza, Stefano Vandi, Elena Antelmi, Francesco Toni, Mino Zucchelli, Giulia Pierangeli, Giuseppe Plazzi
We report the case of a 14-year-old girl with a wide non-compressive pineal cyst, associated with the inability to control her sleep-wake schedule. Actigraphic monitoring showed a 24-hour free-running disorder (tau 26.96 hours). A 24-hour serum melatonin curve assay, with concomitant video-polysomnographic and body-core temperature monitoring, was performed. Melatonin curve showed a blunted nocturnal peak, lower total quantity of melatonin, and prolonged melatonin secretion in the morning, with normal temperature profile and sleep parameters...
October 4, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28986235/alpha-synuclein-epigenetics-mitochondria-metabolism-calcium-traffic-circadian-dysfunction-in-parkinson-s-disease-an-integrated-strategy-for-management
#7
REVIEW
Oliver T Phillipson
The motor deficits which characterise the sporadic form of Parkinson's disease arise from age-related loss of a subset of dopamine neurons in the substantia nigra. Although motor symptoms respond to dopamine replacement therapies, the underlying disease process remains. This review details some features of the progressive molecular pathology and proposes deployment of a combination of nutrients: R-lipoic acid, acetyl-l-carnitine, ubiquinol, melatonin (or receptor agonists) and vitamin D3, with the collective potential to slow progression of these features...
October 3, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28970454/community-pharmacists-knowledge-regarding-donepezil-averse-effects-and-self-care-recommendations-for-insomnia-for-persons-with-ad
#8
Marketa Marvanova, Paul Jacob Henkel
Alzheimer's disease (AD) impacts millions of individuals worldwide. Since no cure is currently available, acetylcholinesterase inhibitors are symptomatic therapy. This study assessed community pharmacists' knowledge regarding donepezil adverse effects (AEs) and self-care recommendations for insomnia management for persons with AD treated with rivastigmine. This is a cross-sectional, standardized telephone survey of community pharmacists (n = 862) in three study areas: West Virginia, North Dakota/South Dakota, and Southern Oregon/Northern California...
July 28, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28966733/sleep-melatonin-and-the-menopausal-transition-what-are-the-links
#9
Shazia Jehan, Giardin Jean-Louis, Ferdinand Zizi, Evan Auguste, Seitikurippu R Pandi-Perumal, Ravi Gupta, Hrayr Attarian, Samy I McFarlane, Rüdiger Hardeland, Amnon Brzezinski
The pineal hormone Melatonin plays an important role in the regulation of the circadian sleep/wake cycle, mood, and perhaps immune functions, carcinogensis and reproduction. The human circadian rhythm of melatonin release from the pineal gland is tightly synchronized with the habitual hours of sleep. Peri- and postmenopausal women often complain of difficulties initiating and/or maintaining sleep, with frequent nocturnal and early morning awakenings. In this review we discuss the pathophysiology of melatonin function as it relates to sleep disorders in menopausal women, highlighting the potential use of exogenous melatonin during the menopausal transition and beyond...
January 2017: Sleep Science
https://www.readbyqxmd.com/read/28966645/relationship-of-nocturnal-concentrations-of-melatonin-gamma-aminobutyric-acid-and-total-antioxidants-in-peripheral-blood-with-insomnia-after-stroke-study-protocol-for-a-prospective-non-randomized-controlled-trial
#10
Wei Zhang, Fang Li, Tong Zhang
Melatonin and gamma-aminobutyric acid (GABA) have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective single-center non-randomized controlled clinical trial performed in the China Rehabilitation Research Center, we analyzed the relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke. Patients during rehabilitation of stroke were recruited and assigned to the insomnia group or non-insomnia group...
August 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28958003/inactivity-is-nycthemeral-endogenously-generated-homeostatically-regulated-and-melatonin-modulated-in-a-free-living-platyhelminth-flatworm
#11
Shauni Omond, Linh M T Ly, Russell Beaton, Jonathan J Storm, Matthew W Hale, John A Lesku
Introduction: Sleep either appeared once early in the evolution of animals, or at multiple instances over evolutionary time. Understanding whether sleep is a diagnostic trait for members of the kingdom Animalia has important implications for our understanding of the evolution of sleep and sleep functions. Unfortunately, knowledge on the phylogenetic breadth of sleep is restricted to vertebrates, a few arthropods and molluscs, and one species of nematode. There is a dearth of information on the other 30 or so animal phyla...
August 24, 2017: Sleep
https://www.readbyqxmd.com/read/28955293/melanopsin-mediated-acute-light-responses-measured-in-winter-and-in-summer-seasonal-variations-in-adults-with-and-without-cataracts
#12
Mirjam Münch, Myriam Ladaique, Ségolène Roemer, Kattayoon Hashemi, Aki Kawasaki
Seasonal adaptation is a ubiquitous behavior seen in many species on both global hemispheres and is conveyed by changing photoperiods. In humans this seasonal adaptation is less apparent, in part because changes in daylength are masked by the use of electrical lighting at night. On the other hand, cataracts which reduce light transmission, may compound seasonal changes related to the reduced daylength of winter. To better understand the effects of different photoperiod lengths in healthy adults without and with cataracts, we tested their melanopsin-mediated light responses in summer vs...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28954634/the-effect-of-agomelatine-and-melatonin-on-sleep-related-eating-a-case-report
#13
Angela Alexandra Zapp, Eva Caroline Fischer, Michael Deuschle
BACKGROUND: Sleep-related eating may occur in the context of mental illness, sleep disorders, or psychopharmacological treatment. Frequently, sleep-related eating leads to severe weight gain and, so far, there are no treatment options for the condition. CASE PRESENTATION: We report the case of a 54-year-old white woman with depression, panic disorder, and sleep apnea under treatment with various antidepressants who developed severe sleep-related eating. Her sleep-related eating completely vanished after addition of agomelatine, it reoccurred after cessation of agomelatine, and vanished again after her re-exposure to another melatonergic drug, extended melatonin...
September 28, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28947337/synthesis-characterization-and-crystal-chemistry-of-tasimelteon-a-melatonin-agonist-in-its-anhydrous-and-hemihydrate-forms
#14
Giampiero Ventimiglia, Sonia Bellomi, Giuseppe Barreca, Lorella Giovannelli, Norberto Masciocchi
Two crystalline forms of Tasimelteon, a drug approved by the US FDA for the treatment of non-24-hour sleep-wake disorder, have been studied by single crystal and powder diffraction analyses, TGA, DSC, spectroscopic and optical methods. The synthetic method forming Tasimelteon is described in detail, with its full analytical, spectroscopic and enantiopurity characterization. Solid Tasimelteon hemihydrate, C15H19NO2⋅0.5H2O, is tetragonal with a = b = 7.3573(2) Å, c = 52.062(2) Å, V = 2818.1(2) Å(3); Z = 8...
September 22, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28937452/use-and-effectiveness-of-sleep-medications-by-parent-report-in-individuals-with-williams-syndrome
#15
Marilee A Martens, Daisha L Seyfer, Rebecca R Andridge, Daniel L Coury
OBJECTIVE: Sleep disorders are common in individuals with Williams syndrome (WS), and sleep disturbance has a significant negative effect on attention, learning, and behavior. The use of sleep-inducing medicine in individuals with WS has not been widely investigated. The objective of this study was to evaluate the use and effectiveness of sleep medications among a large sample of individuals with WS by parent survey. METHODS: A survey of the use and effectiveness of sleep medications was completed by 513 (of 2846) members of the Williams Syndrome Association...
September 19, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28933565/sleep-duration-nightshift-work-and-the-timing-of-meals-and-urinary-levels-of-8-isoprostane-and-6-sulfatoxymelatonin-in-japanese-women
#16
Chisato Nagata, Takashi Tamura, Keiko Wada, Kie Konishi, Yuko Goto, Yasuko Nagao, Kazuhiro Ishihara, Satoru Yamamoto
It has been hypothesized that disruption of circadian rhythms affects human health. Shift work and sleep deprivation are thought to disrupt the normal light-dark cycle, although the disruption due to shiftwork may be dependent on sleep deprivation. Both conditions have been suggested to be associated with an increased risk of cardiometabolic disorders. Non-photic environmental factors, such as the timing of eating, are also thought to regulate circadian rhythm and thus, may have effects on health, but the evidence from human studies is scarce...
September 21, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28932301/melatonin-level-variations-with-different-behavioural-risk-factors-in-obese-female-patients
#17
Ana Malazonia, Tamar Zerekidze, Elen Giorgadze, Natia Chkheidze, Ketevan Asatiani
AIM: The role of behavioural factors and sleep duration and quality is important in the pathogenesis of obesity. The aim of our study was to evaluate the effects of behavioural risk factors on melatonin secretion in women. SUBJECTS AND METHODS: In total, 120 female patients were enrolled in the study and divided into two groups according to the body mass index. Detailed history, anthropometric measurements, urine and blood samples were evaluated for each patient...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28921528/practitioner-review-treatment-of-chronic-insomnia-in-children-and-adolescents-with-neurodevelopmental-disabilities
#18
REVIEW
Oliviero Bruni, Marco Angriman, Fabrizio Calisti, Alessandro Comandini, Giovanna Esposito, Samuele Cortese, Raffaele Ferri
BACKGROUND: Sleep disturbances, in particular insomnia, represent a common problem in children with neurodevelopmental disabilities (NDDs). Currently, there are no approved medications for insomnia in children by the US Food and Drug Administration or European Medicines Agency and therefore they are prescribed off-label. We critically reviewed pediatric literature on drugs as well as nonpharmacological (behavioral) interventions used for sleep disturbances in children with NDDs. METHODS: PubMed, Ovid (including PsycINFO, Ovid MEDLINE(®) , and Embase), and Web of Knowledge databases were searched through February 12, 2017, with no language restrictions...
September 18, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28911277/analysis-of-different-melatonin-secretion-patterns-in-children-with-sleep-disorders-melatonin-secretion-patterns-in-children
#19
Ana Checa-Ros, Antonio Muñoz-Hoyos, Antonio Molina-Carballo, Antonio Muñoz-Gallego, Susana Narbona-Galdó, Antonio Jerez-Calero, María Del Carmen Augustín-Morales
The objective of this study was to analyze circadian patterns of urinary 6-sulphatoxymelatonin (aMT6s) excretion in children with primary sleep disorders in comparison with healthy controls. A total of 124 control children and 124 patients (aged 4-14 years) diagnosed with diverse primary sleep disorders were recruited. aMT6s concentrations were measured in diurnal and nocturnal urine, as well as in 24-hour urine. aMT6s levels were significantly higher and showed significantly more evident circadian variations in the control group ( P < ...
October 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28899330/rem-sleep-behaviour-disorder-not-just-a-bad-dream
#20
REVIEW
Elie Matar, Simon Jg Lewis
Rapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia characterised by the loss of the normal atonia during the REM stage of sleep, resulting in overt motor behaviours that usually represent the enactment of dreams. Patients will seek medical attention due to sleep-related injuries or unpleasant dream content. Idiopathic RBD which occurs independently of any other disease occurs in up to 2% of the older population. Meanwhile, secondary RBD is very common in association with certain neurodegenerative conditions...
September 18, 2017: Medical Journal of Australia
keyword
keyword
77544
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"