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https://www.readbyqxmd.com/read/27894231/evidence-of-exposure-to-cytostatic-drugs-in-healthcare-staff-a-review-of-recent-literature
#1
Pablo Martín Lancharro, Nuria De Castro-Acuña Iglesias, Francisco-Javier González-Barcala, José Domingo Moure González
OBJECTIVE: Provide updated evidence and learn about the actions that must be implemented in order to prevent the occupational exposure to cytostatic drugs. METHOD: A bibliographic search was carried out on the MEDLINE, COCHRANE PLUS and WEB OF SCIENCE databases, with the terms "surface contamination", "cytostatic drug", "drug preparation", "occupational exposure", "safe handling" and "closed-system transfer device", within the 2010-2015 period. RESULTS: Thirteen articles were selected for review...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27888179/predicting-tuberculosis-risk-in-the-foreign-born-population-of-british-columbia-canada-study-protocol-for-a-retrospective-population-based-cohort-study
#2
Lisa A Ronald, Jonathon R Campbell, Robert F Balshaw, David Z Roth, Kamila Romanowski, Fawziah Marra, Victoria J Cook, James C Johnston
INTRODUCTION: Improved understanding of risk factors for developing active tuberculosis (TB) will better inform decisions about diagnostic testing and treatment for latent TB infection (LTBI) in migrant populations in low-incidence regions. We aim to examine TB risk factors among the foreign-born population in British Columbia (BC), Canada, and to create and validate a clinically relevant multivariate risk score to predict active TB. METHODS AND ANALYSIS: This retrospective population-based cohort study will include all foreign-born individuals who acquired permanent resident status in Canada between 1 January 1985 and 31 December 2013 and acquired healthcare coverage in BC at any point during this period...
November 25, 2016: BMJ Open
https://www.readbyqxmd.com/read/27836513/anticoagulant-therapy-for-symptomatic-calf-deep-vein-thrombosis-cactus-a-randomised-double-blind-placebo-controlled-trial
#3
Marc Righini, Jean-Philippe Galanaud, Hervé Guenneguez, Dominique Brisot, Antoine Diard, Pascale Faisse, Marie-Thérèse Barrellier, Claudine Hamel-Desnos, Christine Jurus, Olivier Pichot, Myriam Martin, Lucia Mazzolai, Clarisse Choquenet, Sandrine Accassat, Helia Robert-Ebadi, Marc Carrier, Grégoire Le Gal, Bernadette Mermilllod, Jean-Pierre Laroche, Henri Bounameaux, Arnaud Perrier, Susan R Kahn, Isabelle Quere
BACKGROUND: The efficacy and safety of anticoagulant treatment is not established for patients with acute symptomatic deep vein thrombosis (DVT) of the calf. We aimed to assess whether therapeutic anticoagulation is superior to placebo in patients with symptomatic calf DVT. METHODS: In this randomised, double-blind, placebo-controlled trial, we enrolled low-risk outpatients (without active cancer or previous venous thromboembolic disease) with a first acute symptomatic DVT in the calf from 23 university medical centres or community medical clinics in Canada, France, and Switzerland...
November 7, 2016: Lancet Haematology
https://www.readbyqxmd.com/read/27826153/need-for-formal-specialization-in-pharmacy-in-canada-a-survey-of-hospital-pharmacists
#4
Jonathan Penm, Neil J MacKinnon, Derek Jorgenson, Jun Ying, Jennifer Smith
BACKGROUND: The Blueprint for Pharmacy was a collaborative initiative involving all of the major pharmacy associations in Canada. It aimed to coordinate, facilitate, and be a catalyst for changes required to align pharmacy practice with the health care needs of Canadians. In partial fulfilment of this mandate, a needs assessment for specialist certification for pharmacists was conducted. OBJECTIVE: To conduct a secondary analysis of data from the needs assessment to determine the perceptions of hospital pharmacists regarding a formal certification process for pharmacist specialties in Canada...
September 2016: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/27808023/searching-for-best-direction-in-healthcare-distilling-opportunities-priorities-and-responsibilities
#5
Terrence Montague, Amédé Gogovor, Lucas Marshall, Bonnie Cochrane, Sara Ahmed, Emily Torr, John Aylen, Joanna Nemis-White
Canada's health and its care are evolving. Evidence from serial Health Care in Canada surveys of the public and health professionals over the last two decades reveal a persistent sense of care quality, despite an aging population, decreasing levels of good and excellent health, increasing prevalence of chronic illnesses; and sub-optimal access to timely and patient-centred care. Stakeholders are, however, somewhat pessimistic and many sense complete rebuilding, or major changes, may be necessary. To improve access, the primary health concern of all Canadians - increasing medical and nursing school enrolment, and requiring professionals to work in teams - have attracted increasingly high support from both the public and professionals...
2016: Healthcare Quarterly
https://www.readbyqxmd.com/read/27799608/multicenter-study-of-environmental-contamination-with-cyclophosphamide-ifosfamide-and-methotrexate-in-48-canadian-hospitals
#6
Céline Poupeau, Cynthia Tanguay, Nicolas J Caron, Jean-François Bussières
CONTEXT: Oncology workers are occupationally exposed to antineoplastic drugs. This exposure can induce adverse health effects. In order to reduce their exposure, contamination on surfaces should be kept as low as possible. OBJECTIVES: To monitor environmental contamination with cyclophosphamide, ifosfamide, and methotrexate in oncology pharmacy and patient care areas in Canadian hospitals. To describe the impact of some factors that may limit contamination. METHODS: This is a descriptive study...
October 31, 2016: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/27774739/physician-agreement-regarding-the-expansion-of-pharmacist-professional-activities-in-the-management-of-patients-with-asthma
#7
Audrey Tilly-Gratton, Alexandrine Lamontagne, Lucie Blais, Simon L Bacon, Pierre Ernst, Roland Grad, Kim L Lavoie, Martha L McKinney, Eve Desplats, Francine M Ducharme
BACKGROUND: Asthma control remains suboptimal in Canada. Expansion of pharmacist's professional activities offers the opportunity to improve the interdisciplinary management of patients with asthma. OBJECTIVE: The aim of this study was to determine the level of agreement of physicians regarding the expansion of pharmacists' professional activities in the management of asthma patients. METHODS: We conducted a survey of randomly selected Quebec physicians in family medicine, paediatrics and emergency medicine...
October 24, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27737686/effectiveness-of-a-pharmacist-driven-intervention-in-copd-epic-study-protocol-for-a-randomized-controlled-trial
#8
Erin Davis, Carlo Marra, John-Michael Gamble, Jamie Farrell, Joe Lockyer, J Mark FitzGerald, Waseem Abu-Ashour, Charlie Gillis, John Hawboldt
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are often nonadherent with medications and have poor inhaler technique. Community pharmacists can help to improve health-related quality of life and overall outcomes in patients with COPD. We aim to measure the effectiveness of a systematic, pharmacist-driven intervention on patients with diagnosed COPD. METHODS/DESIGN: This pragmatic, parallel-group, cluster randomized controlled trial is designed to determine the effectiveness of a multifactorial, pharmacist-led intervention on medication adherence, inhaler technique, health-related quality of life, health care resource utilization including COPD exacerbations, and use of medications...
October 13, 2016: Trials
https://www.readbyqxmd.com/read/27708674/a-randomized-trial-of-a-community-based-approach-to-dyslipidemia-management-pharmacist-prescribing-to-achieve-cholesterol-targets-rxact-study
#9
Ross T Tsuyuki, Meagen Rosenthal, Glen J Pearson
BACKGROUND: Dyslipidemia is an important risk factor for cardiovascular disease but is suboptimally managed. Pharmacists are accessible primary care professionals and with expanded scopes of practice (including prescribing), could identify and manage patients with dyslipidemia. We sought to evaluate the effect of pharmacist prescribing of dyslipidemia medications on the proportion of participants achieving target LDL-cholesterol (LDL-c) levels. METHODS: We conducted a randomized controlled trial in 14 community pharmacies in Alberta, Canada...
September 2016: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/27665002/housing-first-improves-adherence-to-antipsychotic-medication-among-formerly-homeless-adults-with-schizophrenia-results-of-a-randomized-controlled-trial
#10
Stefanie N Rezansoff, Akm Moniruzzaman, Seena Fazel, Lawrence McCandless, Ric Procyshyn, Julian M Somers
Adherence to antipsychotic medication is a significant challenge among homeless patients. No experimental trials have investigated the impact of Housing First on adherence among patients with schizophrenia. We investigated whether Housing First in congregate and scattered-site configurations resulted in superior adherence compared to usual care. Adult participants (n = 165) met criteria for homelessness, schizophrenia, and initiation of antipsychotic pharmacotherapy prior to recruitment to an unblinded, 3-arm randomized controlled trial in Vancouver, Canada...
September 24, 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/27663392/community-dwelling-older-people-s-attitudes-towards-deprescribing-in-canada
#11
Caroline Sirois, Nicole Ouellet, Emily Reeve
BACKGROUND: While there is evidence that supervised withdrawal of inappropriate medications might be beneficial for individuals with polypharmacy, little is known about their attitudes towards deprescribing. OBJECTIVE: This study aimed to describe the situation among older community-dwelling Canadians. METHODS: A self-administered survey was adapted from the Patients' Attitudes Towards Deprescribing questionnaire and distributed to 10 community pharmacies and 2 community centers...
August 31, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27661618/community-pharmacists-views-and-practices-regarding-natural-health-products-sold-in-community-pharmacies
#12
Ubaka Ogbogu, Candace Necyk
BACKGROUND: Reports of regulatory and evidentiary gaps have raised concerns about the marketing and use of natural health products (NHPs). The majority of NHPs offered for sale are purchased at a community pharmacy and pharmacists are "front-line" health professionals involved in the marketing and provision of NHPs. To date, the involvement of pharmacists in pharmacy care involving NHPs and the degree to which concerns over the safety, efficacy, marketing and regulation of NHPs are addressed in pharmacy care in Canada have not been studied...
2016: PloS One
https://www.readbyqxmd.com/read/27584068/observations-on-the-2016-world-congress-on-continuing-professional-development-advancing-learning-and-care-in-the-health-professions
#13
Mary G Turco, Robert B Baron
The 2016 World Congress on Continuing Professional Development: Advancing Learning and Care in the Health Professions took place in San Diego, California, March 17-19, 2016. Hosts were the Association for Hospital Medical Education (AHME), Alliance for Continuing Education in the Health Professionals (ACEhp), and Society for Academic Continuing Medical Education (SACME). The target audience was the international community working to improve medical (CME), nursing (CNE), pharmacy (CPE), and interprofessional (CIPE) continuing education (CE) and continuing professional development (CPD)...
2016: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/27581815/community-pharmacists-assisting-in-total-cardiovascular-health-cpatch-a-cluster-randomized-controlled-trial-testing-a-focused-adherence-strategy-involving-community-pharmacies
#14
David F Blackburn, Charity D Evans, Dean T Eurich, Kerry D Mansell, Derek J Jorgenson, Jeff G Taylor, William M Semchuk, Yvonne M Shevchuk, Alfred J Remillard, David A Tran, Anne P Champagne
STUDY OBJECTIVE: To test a brief intervention for preventing statin nonadherence among community pharmacy patrons. DESIGN: Prospective, cluster-randomized, controlled trial (the Community Pharmacists Assisting in Total Cardiovascular Health [CPATCH] trial). SETTING: Thirty community pharmacies in Saskatchewan, Canada. PATIENTS: Participating pharmacies were randomized to 15 intervention pharmacies where a brief statin adherence intervention was delivered by pharmacists (intervention group [907 patients]) or 15 usual care pharmacies where no statin adherence intervention was delivered (usual care group [999 patients]) to new users of statins (defined as less than 1 yr of statin therapy)...
October 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27568359/use-of-standardised-patients-to-assess-antibiotic-dispensing-for-tuberculosis-by-pharmacies-in-urban-india-a-cross-sectional-study
#15
Srinath Satyanarayana, Ada Kwan, Benjamin Daniels, Ramnath Subbaraman, Andrew McDowell, Sofi Bergkvist, Ranendra K Das, Veena Das, Jishnu Das, Madhukar Pai
BACKGROUND: India's total antibiotic use is the highest of any country. Patients often receive prescription-only drugs directly from pharmacies. Here we aimed to assess the medical advice and drug dispensing practices of pharmacies for standardised patients with presumed and confirmed tuberculosis in India. METHODS: In this cross-sectional study in the three Indian cities Delhi, Mumbai, and Patna, we developed two standardised patient cases: first, a patient presenting with 2-3 weeks of pulmonary tuberculosis symptoms (Case 1); and second, a patient with microbiologically confirmed pulmonary tuberculosis (Case 2)...
November 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27568002/factors-associated-with-optimal-pharmacy-refill-adherence-for-antiretroviral-medications-and-plasma-hiv-rna-non-detectability-among-hiv-positive-crack-cocaine-users-a-prospective-cohort-study
#16
Kanna Hayashi, Evan Wood, Thomas Kerr, Huiru Dong, Paul Nguyen, Cathy M Puskas, Silvia Guillemi, Julio S G Montaner, Michael-John Milloy
BACKGROUND: Crack cocaine use is known to contribute to poor adherence to antiretroviral medications; however, little is known about facilitators of or barriers to effective HIV treatment use among HIV-infected crack cocaine users. We sought to identify correlates of optimal pharmacy refill adherence for antiretroviral medications and plasma HIV RNA viral load (pVL) suppression among this population. METHODS: Data from a prospective cohort of HIV-positive people who use illicit drugs in Vancouver, Canada, were linked to comprehensive HIV clinical monitoring and pharmacy dispensation records...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27559187/significant-published-articles-for-pharmacy-nutrition-support-practice-in-2014-and-2015
#17
Roland N Dickerson, Vanessa J Kumpf, Allison B Blackmer, Angela L Bingham, Anne M Tucker, Joseph V Ybarra, Michael D Kraft, Todd W Canada
PURPOSE: To assist the pharmacy clinician engaged in nutrition support in staying current with the most pertinent literature. METHODS: Several experienced board-certified clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2014 and 2015 that they considered to be important to their practice. Only those articles available in print format were considered for potential inclusion. Articles available only in preprint electronic format were not evaluated...
July 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27557840/claims-for-disease-modifying-therapy-by-alberta-non-insured-health-benefits-clients
#18
Cheryl Barnabe, Bonnie Healy, Andrew Portolesi, Gilaad G Kaplan, Brenda Hemmelgarn, Charles Weaselhead
BACKGROUND: Uncontrolled disease activity in inflammatory diseases of the joints, skin and bowel leads to morbidity and disability. Disease-modifying therapies are widely used to suppress this disease activity, but cost-coverage is variable. For Treaty First Nations and Inuit people in Canada without alternative private or public health insurance, cost-coverage for disease-modifying therapy is provided through Non-Insured Health Benefits (NIHB). Our objective was to describe the prevalence and patterns of treatment with disease-modifying therapy for the NIHB claimant population, and also examine adjuvant therapy (analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids) use...
2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27538362/designing-an-adverse-drug-event-reporting-system-to-prevent-unintentional-reexposures-to-harmful-drugs-study-protocol-for-a-multiple-methods-design
#19
David Peddie, Serena S Small, Katherin Badke, Maeve E Wickham, Chantelle Bailey, Adam Chruscicki, Christine Ackerley, Ellen Balka, Corinne M Hohl
BACKGROUND: Adverse drug events (ADEs) are unintended and harmful events related to medication use. Up to 30% of serious ADEs recur within six months because culprit drugs are unintentionally represcribed and redispensed. Improving the electronic communication of ADE information between care providers, and across care settings, has the potential to reduce recurrent ADEs. OBJECTIVE: We aim to describe the methods used to design Action ADE, a novel electronic ADE reporting system that can be leveraged to prevent unintentional reexposures to harmful drugs in British Columbia, Canada...
2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27513573/barriers-to-viral-suppression-among-female-sex-workers-role-of-structural-and-intimate-partner-dynamics
#20
Putu Duff, Shira Goldenberg, Kathleen Deering, Julio Montaner, Paul Nguyen, Sabina Dobrer, Kate Shannon
OBJECTIVE: Despite global evidence that sex workers (SWs) are disproportionately impacted by HIV, data on HIV treatment outcomes among SWs living with HIV remains sparse. This study examined the correlates of undetectable plasma viral load (pVL) among street- and off-street SWs living with HIV and on antiretroviral therapy (ART) in Metro Vancouver, Canada. METHODS: Analyses drew on data (2010-2014) from a longitudinal cohort of SWs (An Evaluation of Sex Workers Health Access) and confidential linkages with the Drug Treatment Program (DTP) data on ART dispensation and outcomes...
September 1, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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