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https://www.readbyqxmd.com/read/28663062/community-pharmacist-training-and-communication-network-and-drug-related-problems-in-patients-with-ckd-a-multicenter-cluster-randomized-controlled-trial
#1
Lyne Lalonde, Patricia Quintana-Bárcena, Anne Lord, Robert Bell, Valérie Clément, Anne-Marie Daigneault, Marie-Ève Legris, Sara Letendre, Marie Mouchbahani, Ghaya Jouini, Joëlle Azar, Élisabeth Martin, Djamal Berbiche, Stephanie Beaulieu, Sébastien Beaunoyer, Émilie Bertin, Marianne Bouvrette, Noémie Charbonneau-Séguin, Jean-François Desrochers, Katherine Desforges, Ariane Dumoulin-Charette, Sébastien Dupuis, Maryame El Bouchikhi, Roxanne Forget, Marianne Guay, Jean-Phillippe Lemieux, Claudia Morin-Bélanger, Isabelle Noël, Stephanie Ricard, Patricia Sauvé, François Ste-Marie Paradis
BACKGROUND: Appropriate training for community pharmacists may improve the quality of medication use. Few studies have reported the impact of such programs on medication management for patients with chronic kidney disease (CKD). STUDY DESIGN: Multicenter, cluster-randomized, controlled trial. SETTING & PARTICIPANTS: Patients with CKD stage 3a, 3b, or 4 from 6 CKD clinics (Quebec, Canada) and their community pharmacies. INTERVENTION: Each cluster (a pharmacy and its patients) was randomly assigned to either ProFiL, a training-and-communication network program, or the control group...
June 26, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28653260/contributions-of-community-pharmacists-to-patients-on-antidepressants-a-qualitative-study-among-key-informants
#2
Laurence Guillaumie, Jocelyne Moisan, Jean-Pierre Grégoire, Denis Villeneuve, Clément Beaucage, Lilianne Bordeleau, Sophie Lauzier
Background Patients with an antidepressant drug treatment (ADT) report unmet needs and a significant proportion stop their ADT prematurely. Community pharmacists can play a key role in supporting these patients. Objective To explore the perspectives of various leaders in health care about the current and potential contributions of community pharmacists to patients on ADT. Setting The province of Quebec (Canada). Method We conducted a qualitative descriptive exploratory study using interviews among leaders who were involved in health care services, pharmaceutical services, physician and pharmacist education, as well as patient and healthcare professional associations...
June 26, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28623124/development-and-implementation-of-the-compensation-plan-for-pharmacy-services-in-alberta-canada
#3
Rene R Breault, Jeff G Whissell, Christine A Hughes, Theresa J Schindel
OBJECTIVE: To describe experiences with development and implementation of a compensation plan for pharmacy services delivered by pharmacists in community pharmacies. SETTING: Community pharmacy practice in Alberta, Canada. PRACTICE DESCRIPTION: Pharmacists in Alberta have one of the most progressive scopes of practice in North America. They have authority to prescribe drugs independently, administer drugs by injection, access electronic health records, and order laboratory tests...
June 13, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28615153/-click-for-closer-care-a-content-analysis-of-community-pharmacy-websites-in-four-countries
#4
Sandra Zwier
BACKGROUND: Combinations of professional and commercial communication are typically very controversial, particularly in health care communication on the Internet. Websites of licensed community pharmacies on the other hand tend to raise remarkably little controversy, although they typically contain controversial combinations of clinical and commercial services previously unprecedented in professional health care communication. OBJECTIVE: The aim of this study was to fill the void of knowledge about the combination of clinical and commercial services presented on the websites of licensed community pharmacies...
June 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28595280/estimating-national-level-exposure-to-antineoplastic-agents-in-the-workplace-carex-canada-findings-and-future-research-needs
#5
Amy L Hall, Paul A Demers, George Astrakianakis, Calvin Ge, Cheryl E Peters
Objectives: Occupational exposure to antineoplastic agents occurs in various environments and is associated with increased cancer risk and adverse reproductive outcomes. National-level information describing the location and extent of occupational exposure to antineoplastic agents is unavailable in Canada and most other countries. CAREX Canada aimed to estimate the prevalence and relative levels of occupational exposures to antineoplastic agents across work setting, occupation, and sex...
June 8, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28535455/the-effectiveness-of-telemedicine-delivered-opioid-agonist-therapy-in-a-supervised-clinical-setting
#6
Joseph K Eibl, Graham Gauthier, David Pellegrini, Jeffery Daiter, Michael Varenbut, John C Hogenbirk, David C Marsh
OBJECTIVE: Opioid use disorder has been declared a public health crisis across North America and opioid agonist therapy (OAT) is the standard of care for these patients. Despite the increasing adoption of telemedicine as a delivery method for OAT, its effectiveness has not yet been evaluated against traditional in-person treatment. This study compared treatment outcomes for in-person versus telemedicine-delivered OAT. METHODS: We conducted a non-randomized cohort comparison study using an administrative database for patients who commenced OAT between 2011 and 2012 across 58 clinic sites in the province of Ontario, Canada...
May 17, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28520804/inpatient-z-drug-use-commonly-exceeds-safe-dosing-recommendations
#7
Todd C Lee, André Bonnici, Robyn Tamblyn, Emily G McDonald
IMPORTANCE: In 2016 recommendations for safer prescribing practices were circulated to all doctors in one of Canada's largest provinces, by the college of physicians, following a coroner's inquest into a vehicular death related to Z-drug use. We sought to determine how frequently Z-drug prescriptions in our institution were not adhering to these recommendations. DESIGN: Retrospective cohort study. SETTING: McGill University Health Centre, an 832-bed tertiary care institution in Montréal, Canada...
2017: PloS One
https://www.readbyqxmd.com/read/28454044/unintended-impacts-of-regulatory-changes-to-british-columbia-methadone-maintenance-program-on-addiction-and-hiv-related-outcomes-an-interrupted-time-series-analysis
#8
M Eugenia Socías, Evan Wood, Ryan McNeil, Thomas Kerr, Huiru Dong, Jean Shoveller, Julio Montaner, M-J Milloy
BACKGROUND: In February 2014, several regulatory reforms were introduced to the methadone maintenance treatment (MMT) program in British Columbia, Canada, including a switch to a ten-times more concentrated methadone formulation and restrictions in pharmacy delivery services. We evaluated possible unintended effects of these changes on illicit drug use patterns and HIV treatment outcomes among HIV-positive opioid users. METHODS: Data was drawn from ACCESS, a prospective community-recruited cohort of HIV-positive people who use illicit drugs in Vancouver, Canada...
April 25, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28435984/patterns-predictors-and-persistence-of-chronic-sedative-use-a-population-based-observational-study-of-older-adults-in-british-columbia-canada
#9
Steven G Morgan, Deirdre Weymann
BACKGROUND: Benzodiazepines and benzodiazepine-like sedatives (zopiclone, zolpidem and zaleplon) are commonly prescribed to treat anxiety and insomnia but are contraindicated for chronic use. We sought to study the persistence, over multiple years, of chronic use of benzodiazepines and benzodiazepine-like sedatives among community-dwelling adults in British Columbia, Canada. METHODS: This is a retrospective analysis of linked health data for adults aged 50 to 69 in 2004 who resided in British Columbia, Canada, between 2004 and 2013...
August 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28315858/how-does-culture-affect-experiential-training-feedback-in-exported-canadian-health-professional-curricula
#10
Kerry Wilbur, Rasha Mousa Bacha, Somaia Abdelaziz
Objectives: To explore feedback processes of Western-based health professional student training curricula conducted in an Arab clinical teaching setting. Methods: This qualitative study employed document analysis of in-training evaluation reports (ITERs) used by Canadian nursing, pharmacy, respiratory therapy, paramedic, dental hygiene, and pharmacy technician programs established in Qatar. Six experiential training program coordinators were interviewed between February and May 2016 to explore how national cultural differences are perceived to affect feedback processes between students and clinical supervisors...
March 17, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28272135/the-adherence-gap-a-longitudinal-examination-of-men-s-and-women-s-antiretroviral-therapy-adherence-in-british-columbia-2000-2014
#11
Cathy M Puskas, Angela Kaida, Cari L Miller, Wendy Zhang, Benita Yip, Neora Pick, Julio S G Montaner, Robert S Hogg
OBJECTIVE: The aim of this study was to observe the effect of sex on attaining optimal adherence to combination antiretroviral therapy (cART) longitudinally while controlling for known adherence confounders - IDU and ethnicity. DESIGN: Using the population-based HAART Observational Medical Evaluation and Research cohort, data were collected from HIV-positive adults, aged at least 19 years, receiving cART in British Columbia, Canada, with data collected between 2000 and 2014...
March 27, 2017: AIDS
https://www.readbyqxmd.com/read/28229892/safety-and-efficacy-of-opicinumab-in-acute-optic-neuritis-renew-a-randomised-placebo-controlled-phase-2-trial
#12
RANDOMIZED CONTROLLED TRIAL
Diego Cadavid, Laura Balcer, Steven Galetta, Orhan Aktas, Tjalf Ziemssen, Ludo Vanopdenbosch, Jette Frederiksen, Mark Skeen, Glenn J Jaffe, Helmut Butzkueven, Focke Ziemssen, Luca Massacesi, Yi Chai, Lei Xu, Stefanie Freeman
BACKGROUND: The human monoclonal antibody opicinumab (BIIB033, anti-LINGO-1) has shown remyelinating activity in preclinical studies. We therefore assessed the safety and tolerability, and efficacy of opicinumab given soon after a first acute optic neuritis episode. METHODS: This randomised, double-blind, placebo-controlled, phase 2 study (RENEW) was done at 33 sites in Australia, Canada, and Europe in participants (aged 18-55 years) with a first unilateral acute optic neuritis episode within 28 days from study baseline...
March 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28220518/describing-student-performance-a-comparison-among-clinical-preceptors-across-cultural-contexts
#13
Kerry Wilbur, Noha Hassaballa, Omaima S Mahmood, Emily K Black
CONTEXT: Health professional student evaluation during experiential training is notably subjective and assessor judgements may be affected by socio-cultural influences. OBJECTIVES: This study sought to explore how clinical preceptors in pharmacy conceptualise varying levels of student performance and to identify any contextual differences that may exist across different countries. METHODS: The qualitative research design employed semi-structured interviews...
February 20, 2017: Medical Education
https://www.readbyqxmd.com/read/28213493/development-of-the-critical-care-pharmacotherapy-trials-network
#14
Seth R Bauer, Prasad E Abraham, Jeffrey F Barletta, Gretchen M Brophy, Brian L Erstad, Jeffrey P Gonzales, Curtis E Haas, Robert MacLaren, Eric W Mueller, Keith M Olsen, Ishaq Lat
PURPOSE: The development of the Critical Care Pharmacotherapy Trials Network (CCPTN) as a model for practice-based pharmacotherapy research is described. SUMMARY: The CCPTN was formed in 2010 as a collaborative research network dedicated to scientific investigation in the field of critical care pharmacotherapy. The CCPTN organizational structure is consistent with many professional pharmacy and interdisciplinary organizations and organized into 3 primary domains: executive committee, working committees, and network membership...
March 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28193217/measuring-medication-adherence-in-patients-with-incident-hypertension-a-retrospective-cohort-study
#15
Karen L Tang, Hude Quan, Doreen M Rabi
BACKGROUND: Though pharmacy claims data are commonly used to study medication adherence, there remains no standard operational definition for adherence especially for patients on multiple medications. Even when studies use the same terminology, the actual methods of calculating adherence can differ drastically. It is unclear whether the use of different definitions results in different conclusions regarding adherence and associated outcomes. The objective of our study was to compare adherence rates and associations with mortality using different operational definitions of adherence, and using various methods of handling concurrent medication use...
February 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28190480/documenting-the-evolution-of-the-relationship-between-the-pharmacy-support-workforce-and-pharmacists-to-support-patient-care
#16
Tamara Koehler, Andrew Brown
Since 2009 there has been a focus on the relationship between pharmacy technicians, pharmacy support workforce cadres and pharmacists in the literature. 2009-2011 saw a framework of role evolution develop, with publications from 2012 to 2015 documenting further maturity in the development of practice models for improved patient care and optimal use of personnel. The dominant narrative in the published academic literature has been made by certain high- income countries (mainly Canada, Denmark, United Kingdom and the United States of America)...
March 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28186715/adoption-of-the-nova-scotia-canada-community-pharmacy-medication-management-program-1-year-post-initiation
#17
Heidi J Deal, Charmaine A Cooke, Ethel M Langille Ingram, Ingrid S Sketris
BACKGROUND: Pharmacists conduct medication reviews to optimize drug therapy. Each jurisdiction implements and funds these programs differently. OBJECTIVE: To describe the uptake of the first year of a community pharmacy medication review program reimbursed by the publically insured seniors' drug benefit program in Nova Scotia, Canada. METHODS: This retrospective analysis included 294 pharmacies and 105,000 beneficiaries enrolled in the Nova Scotia Seniors' Pharmacare Program...
February 1, 2017: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/28154015/potential-ways-to-address-shortage-situations-of-99-mo-99m-tc
#18
Leah M Filzen, Lacey R Ellingson, Andrew M Paulsen, Joseph C Hung
(99m)Tc, the most common radioisotope used in nuclear medicine, is produced in a nuclear reactor from the decay of (99)Mo. There are only a few aging nuclear reactors around the world that produce (99)Mo, and one of the major contributors, the National Research Universal (Canada), ceased production on October 31, 2016. The National Research Universal produced approximately 40% of the world's (99)Mo supply, so with its shut down, shortages of (99)Mo/(99m)Tc are expected. Methods: Nuclear pharmacies and nuclear medicine departments throughout the United States were contacted and asked to provide their strategies for coping with a shortage of (99)Mo/(99m)Tc...
March 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28118682/multiple-mini-interview-predictive-validity-for-performance-on-a-pharmacy-licensing-examination
#19
Andrea J Cameron, Linda D MacKeigan, Nicholas Mitsakakis, John A Pugsley
CONTEXT: Predictive validity studies on the use of the multiple mini-interview (MMI) have been primarily in medicine. OBJECTIVES: This study sought to determine the predictive validity of the MMI for performance within a pharmacy programme and on the Pharmacy Examining Board of Canada (PEBC) Qualifying Examination for licensure, and to compare the predictive validity of the MMI with that of pre-pharmacy grade point average (GPA) and Pharmacy College Admission Test (PCAT) score...
January 24, 2017: Medical Education
https://www.readbyqxmd.com/read/28118206/the-gender-gap-a-longitudinal-examination-of-men-s-and-women-s-art-adherence-in-british-columbia-2000-2014
#20
Cathy M Puskas, Angela Kaida, Cari L Miller, Wendy Zhang, Benita Yip, Neora Pick, Julio S G Montaner, Robert S Hogg
OBJECTIVE: The aim of this study was to observe the effect of sex on attaining optimal adherence to combination antiretroviral therapy (cART) longitudinally, while controlling for known adherence confounders: injection drug use (IDU) and ethnicity. DESIGN: Using the population-based HAART Observational Medical Evaluation and Research (HOMER) cohort, data were collected from HIV-positive adults, ≥19 years, receiving cART in British Columbia (BC), Canada, with data collected between 2000 and 2014...
January 21, 2017: AIDS
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