Ioan Opris, Xiaohong Dai, Dawn M G Johnson, Francisco J Sanchez, Luz M Villamil, Songtao Xie, Cecelia R Lee-Hauser, Stephano Chang, Larry M Jordan, Brian R Noga
The distribution of locomotor-activated neurons in the brainstem of the cat was studied by c- Fos immunohistochemistry in combination with antibody-based cellular phenotyping following electrical stimulation of the mesencephalic locomotor region (MLR) - the anatomical constituents of which remain debated today, primarily between the cuneiform (CnF) and the pedunculopontine tegmental nuclei (PPT). Effective MLR sites were co-extensive with the CnF nucleus. Animals subject to the locomotor task showed abundant Fos labeling in the CnF, parabrachial nuclei of the subcuneiform region, periaqueductal gray, locus ceruleus (LC)/subceruleus (SubC), Kölliker-Fuse, magnocellular and lateral tegmental fields, raphe, and the parapyramidal region...
2019: Frontiers in Systems Neuroscience