keyword
MENU ▼
Read by QxMD icon Read
search

Quantum biology

keyword
https://www.readbyqxmd.com/read/28099838/osteoarthritis-year-in-review-2016-biomarkers-biochemical-markers
#1
REVIEW
A Mobasheri, A-C Bay-Jensen, W E van Spil, J Larkin, M C Levesque
PURPOSE: The aim of this "Year in Review" article is to summarize and discuss the implications of biochemical marker related articles published between the Osteoarthritis Research Society International (OARSI) 2015 Congress in Seattle and the OARSI 2016 Congress in Amsterdam. METHODS: The PubMed/MEDLINE bibliographic database was searched using the combined keywords: 'biomarker' and 'osteoarthritis'. The PubMed/MEDLINE literature search was conducted using the Advanced Search Builder function (http://www...
January 2, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28099170/exploring-the-ability-of-the-nalidixate-to-sensitize-visible-and-near-infrared-emitting-lanthanide-iii-cations
#2
Svetlana V Eliseeva, Valerii S Liasotkyi, Iurii P Golovach, Pavel G Doga, Valery P Antonovich, Stéphane Petoud, Svetlana B Meshkova
Recently, a strong interest has been directed towards near-infrared (NIR) emitting lanthanide(III) compounds as they do possess complementary advantages in respect to organic molecules and semi-conductor nanocrystals, especially in the fields of biological analysis and imaging. To benefit from their emission, a key requirement to fulfill is the sensitization of lanthanide(III) cations with an appropriate chromophore. This condition is especially challenging to address for the lanthanide(III) cations emitting in the NIR...
January 18, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28092502/capacity-evaluation-of-a-quantum-based-channel-in-a-biological-context
#3
Valeria Loscri, Anna Maria Vegni
Nanotechnology, as enabler of the miniaturization of devices in a scale ranging from 1 to few hundreds of nm , represents a viable solution for " alternative" communication paradigms that could be effective in complex networked systems, as body area networks. Traditional communication paradigms are not effective in the context of joint body and nano-networked systems, for several reasons, and then novel approaches have been investigated such as nanomechanical, electromagnetic, acoustic, molecular, etc. On the other hand, quantum phenomena represent a natural direction for developing nanotechnology, since it has to be considered as a new scale where new phenomena can occur and can be exploited for information purpose...
December 2016: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28092424/continuous-films-of-self-assembled-graphene-quantum-dots-for-n-type-doping-of-graphene-by-uv-triggered-charge-transfer
#4
Myung Jin Park, Yuna Kim, Youngsoo Kim, Byung Hee Hong
The demands to examine components serving as one of the active layers in heterostructures of 2D materials have been recently increasing. Nanomaterials synthesized from a solution process and their self-assembly can provide a promising route to build a new type of mixed dimensional heterostructures, and several methodologies have been reported previously to construct 2D assemblies from colloidal nanostructures in solution. Graphene quantum dots (GQDs), receiving much interest due to the tunable optical band gap and the capability of chemical functionalization, are considered as emerging nanomaterials for various optoelectronic and biological applications...
January 16, 2017: Small
https://www.readbyqxmd.com/read/28090435/-13-c-metabolomics-nmr-and-iroa-for-unknown-identification
#5
Chaevien S Clendinen, Gregory S Stupp, Bing Wang, Timothy J Garrett, Arthur S Edison
ABSTRACT BACKGROUND: Isotopic Ratio Outlier Analysis (IROA) is an untargeted metabolomics method that uses stable isotopic labeling and LC-HRMS for identification and relative quantification of metabolites in a biological sample under varying experimental conditions. OBJECTIVE: We demonstrate a method using high-sensitivity (13)C NMR to identify an unknown metabolite isolated from fractionated material from an IROA LC-HRMS experiment. METHODS: IROA samples from the nematode Caenorhabditis elegans were fractionated using LC-HRMS using 5 repeated injections and collecting 30 sec fractions...
August 2016: Current Metabolomics
https://www.readbyqxmd.com/read/28088861/ultrasensitive-label-free-nanosensing-and-high-speed-tracking-of-single-proteins
#6
Matz Liebel, James T Hugall, Niek F van Hulst
Label-free detection, analysis and rapid tracking of nanoparticles is crucial for future ultrasensitive sensing applications, ranging from understanding of biological interactions to the study of size dependent classical-quantum transitions. Yet optical techniques to distinguish nanoparticles directly amongst their background remain challenging. Here we present amplified interferometric scattering microscopy (a-iSCAT) as a new all-optical method capable of detecting individual nanoparticles as small as 15 kDa proteins which is equivalent to half a GFP...
January 16, 2017: Nano Letters
https://www.readbyqxmd.com/read/28088748/a-dna-probe-based-on-phosphorescent-resonance-energy-transfer-for-detection-of-transgenic-35s-promoter-dna
#7
Jinzhi Lv, Yanming Miao, Jiajia Yang, Jin Qin, Dongxia Li, Guiqin Yan
A QDs-DNA nano-probe was made by combining Mn-doped ZnS room-temperature phosphorescence (RTP) quantum dots (QDs) and DNA. Then an RTP sensor for quantitative detection of genetically-modified mark sequence cauliflower mosaic virus 35S promoter (Ca MV 35S) DNA was built on basis of phosphorescent resonance energy transfer (PRET). The underlying principles were that a QDs-DNA water-soluble nano-probe was built by connecting single-strand DNA to the surfaces of QDs via a ligand exchange method. This probe had good RTP performance and could well identify Ca MV 35S...
January 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28080028/a-grand-avenue-to-au-nanocluster-electrochemiluminescence
#8
Mahdi Hesari, Zhifeng Ding
In most cases of semiconductor quantum dot nanocrystals, the inherent optical and electrochemical properties of these interesting nanomaterials do not translate into expected efficient electrochemiluminescence or electrogenerated chemiluminescence (ECL) because of the surface-state induction effect. Thus, their low ECL efficiencies, while very interesting to explore, limit their applications. As their electrochemistry is not well-defined, insight into their ECL mechanistic details is also limited. Alternatively, gold nanoclusters possess monodispersed sizes with atomic precision, low and well defined HOMO-LUMO energy gaps, and stable optical and electrochemical properties that make them suitable for potential ECL applications...
January 12, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28079064/lasing-action-from-photonic-bound-states-in-continuum
#9
Ashok Kodigala, Thomas Lepetit, Qing Gu, Babak Bahari, Yeshaiahu Fainman, Boubacar Kanté
In 1929, only three years after the advent of quantum mechanics, von Neumann and Wigner showed that Schrödinger's equation can have bound states above the continuum threshold. These peculiar states, called bound states in the continuum (BICs), manifest themselves as resonances that do not decay. For several decades afterwards the idea lay dormant, regarded primarily as a mathematical curiosity. In 1977, Herrick and Stillinger revived interest in BICs when they suggested that BICs could be observed in semiconductor superlattices...
January 11, 2017: Nature
https://www.readbyqxmd.com/read/28078631/investigation-of-solvent-effects-on-photophysical-properties-of-new-aminophthalimide-derivatives-based-on-methanesulfonate
#10
Ayse Tan, Ebru Bozkurt, Yunus Kara
Novel aminophthalimide derivatives were synthesized starting from (3aR,7aS)-2-(2-hydroxypropyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (9) , and solvent effects on the photo-physical properties of these newly synthesized aminophthalimide derivatives (compounds 14 and 15) were investigated using UV-Vis absorption spectroscopy, steady-state and time-resolved fluorescence measurements. Both absorption and fluorescence spectra exhibited bathochromic shift with the increased polarity of the solvents for both molecules...
January 11, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28075596/yeast-microcapsule-mediated-targeted-delivery-of-diverse-nanoparticles-for-imaging-and-therapy-via-the-oral-route
#11
Xing Zhou, Xiangjun Zhang, Songling Han, Yin Dou, Mengyu Liu, Lin Zhang, Jia Wei Guo, Qing Shi, Genghao Gong, Ruibing Wang, Jiang Hu, Xiaohui Li, Jianxiang Zhang
Targeting of nanoparticles to distant diseased sites after oral delivery remains highly challenging, due to the existence of many biological barriers in the gastrointestinal tract. Here we report targeted oral delivery of diverse nanoparticles in multiple disease models, via a 'Trojan horse' strategy based on a bioinspired yeast capsule (YC). Diverse charged nanoprobes including quantum dots (QDs), iron oxide nanoparticles (IONPs), and assembled organic fluorescent nanoparticles can be effectively loaded into YC through electrostatic force-driven spontaneous deposition, resulting in different diagnostic YC assemblies...
January 11, 2017: Nano Letters
https://www.readbyqxmd.com/read/28069502/synthesis-and-characterization-of-citrate-based-fluorescent-small-molecules-and-biodegradable-polymers
#12
Zhiwei Xie, Jimin P Kim, Qing Cai, Yi Zhang, Jinshan Guo, Ranjodh S Dhami, LiLi, Bin Kong, Yixue Su, Kevin A Schug, Jian Yang
Novel citric acid based photoluminescent dyes and degradable polymers are synthesized via a facile "one-pot" reaction. A comprehensive understanding of the fluorescence mechanisms of the resulting citric acid-based fluorophores is reported. Two distinct types of fluorophores are identified: a thiozolopyridine family with high quantum yield, long lifetime, and exceptional photostability, and a dioxopyridine family with relatively lower quantum yield, multiple lifetimes, and solvent-dependent band shifting behavior...
January 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28068771/perturbation-approach-for-computing-infrared-spectra-of-the-local-mode-of-probe-molecules
#13
Rui-Jie Xue, Adam Grofe, He Yin, Zexing Qu, Jiali Gao, Hui Li
Linear and two-dimensional infrared (IR) spectroscopy of site-specific probe molecules provides an opportunity to gain a molecular-level understanding of the local hydrogen-bonding network, conformational dynamics, and long-range electrostatic interactions in condensed-phase and biological systems. A challenge in computation is to determine the time-dependent vibrational frequencies that incorporate explicitly both nuclear quantum effects of vibrational motions and an electronic structural representation of the potential energy surface...
January 10, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28068539/one-step-synthesis-of-photoluminescent-carbon-dots-with-excitation-independent-emission-for-selective-bioimaging-and-gene-delivery
#14
Xudong Yang, Yang Wang, Xiran Shen, Chunyan Su, Jinghua Yang, Mingjun Piao, Fei Jia, Guanghui Gao, Long Zhang, Quan Lin
Photoluminescent carbon dots (C-dots), as new members of the quantum sized carbon analogues have attracted significant attention due to their unique size, less toxicity, good compatibility and relatively easy surface modification. In this work, we report a simple, low-cost and one-step hydrothermal carbonization approach to synthesize the positively charged C-dots using PEI and FA. From the photoluminescence (PL) measurements, the as-prepared C-dots exhibit good stability and intense PL with the high quantum yield (QY) at Ca...
December 24, 2016: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28059502/chiral-nh-controlled-supramolecular-metallacycles
#15
Jinqiao Dong, Chunxia Tan, Kang Zhang, Yan Liu, Paul J Low, Jianwen Jiang, Yong Cui
Chiral NH functionalities-based discrimination is a key feature of Nature's chemical armory, yet selective binding of biologically active molecules in synthetic systems with high enantioselectivity poses significant challenges. Here we report the assembly of three chiral fluorescent Zn6L6 metallacycles from pyridyl-functionalized Zn(salalen) and/or Zn(salen) complexes. Each of these metallacycles has a nanoscale hydrophobic cavity decorated with six, three or zero chiral NH functionalities and packs into a three-dimensional supramolecular porous framework...
January 6, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28057464/graphene-quantum-dots-for-cancer-targeted-drug-delivery
#16
Daniela Iannazzo, Alessandro Pistone, Marina Salamò, Signorino Galvagno, Roberto Romeo, Salvatore V Giofré, Caterina Branca, Giuseppa Visalli, Angela Di Pietro
A biocompatible and cell traceable drug delivery system Graphene Quantum Dots (GQD) based, for the targeted delivery of the DNA intercalating drug doxorubicin (DOX) to cancer cells, is here reported. Highly dispersible and water soluble GQD, synthesized by acidic oxidation and exfoliation of multi-walled carbon nanotubes (MWCNT), were covalently linked to the tumor targeting module biotin (BTN), able to efficiently recognize biotin receptors over-expressed on cancer cells and loaded with DOX. Biological test performed on A549 cells reported a very low toxicity of the synthesized carrier (GQD and GQD-BTN)...
January 2, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28052473/versatile-interacting-peptide-vip-tags-for-labeling-proteins-with-bright-chemical-reporters
#17
Hannah K Zane, Julia K Doh, Caroline A Enns, Kimberly Elizabeth Beatty
Fluorescence microscopy is an essential tool for the biosciences, enabling the direct observation of proteins in their cellular environment. New methods that facilitate attachment of photostable synthetic fluorophores with genetic specificity are needed to advance the frontiers of biological imaging. Here we describe a new set of small, selective, genetically-encoded tags for proteins based on a heterodimeric coiled-coil interaction between two peptides: CoilY and CoilZ. Proteins expressed as a fusion to CoilZ were selectively labeled with the complementary CoilY fluorescent probe peptide...
January 4, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28051858/quantum-mechanical-enhancement-of-rate-constants-and-kinetic-isotope-effects-for-water-mediated-proton-transfer-in-a-model-biological-system
#18
James W Mazzuca, Chase P Schultz
Biological systems have been shown to shuttle excess protons long distances by taking advantage of tightly organized hydrogen-bonded water bridges in hydrophobic protein cavities, and similar effects have been observed in carbon nanotubes. In this theoretical study we investigate how quantum effects of proton motion impact the rate constants for charge transfer in a model system consisting of a donor and acceptor molecule separated by a single-molecule water bridge. We calculate quantum and classical rate constants for the transfer of an excess proton over two possible paths, one with an H3O(+) intermediate, and one with an OH(-) intermediate...
January 18, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28048935/engineered-diblock-polypeptides-improve-dna-and-gold-solubility-during-molecular-assembly
#19
Nicole A Estrich, Armando Hernandez-Garcia, Renko de Vries, Thomas H LaBean
Programmed molecular recognition is being developed for the bionanofabrication of mixed organic/inorganic supramolecular assemblies for applications in electronics, photonics, and medicine. For example, DNA-based nanotechnology seeks to exploit the easily programmed complementary base-pairing of DNA to direct assembly of complex, designed nanostructures. Optimal solution conditions for bionanofabrication, mimicking those of biological systems, may involve high concentrations of biomacromolecules (proteins, nucleic acids, etc...
January 6, 2017: ACS Nano
https://www.readbyqxmd.com/read/28043119/bioconjugated-nanoparticles-for-biosensing-in-vivo-imaging-and-medical-diagnostics
#20
Brad A Kairdolf, Ximei Qian, Shuming Nie
Bioconjugated nanoparticles are of considerable current interest because materials on the nanometer scale have unique optical, electronic, and magnetic properties with broad applications in biosensing, molecular imaging, and medical diagnostics. In particular, recent advances have led to the development of nanomaterials for a variety of applications, including iron oxide nanocrystals for magnetic resonance imaging (MRI), fluorescent quantum dots (QDs) for multiplexed molecular diagnosis and in vivo imaging, and gold nanoparticles for surface-enhanced Raman scattering...
December 19, 2016: Analytical Chemistry
keyword
keyword
7753
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"