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Wood's lamp

Jung Min Bae, Tae Young Han
No abstract text is available yet for this article.
March 2017: Journal of the American Academy of Dermatology
Uma D Kabra, Katrin Pfuhlmann, Adriana Migliorini, Susanne Keipert, Daniel Lamp, Olle Korsgren, Moritz Gegg, Stephen C Woods, Paul T Pfluger, Heiko Lickert, Charles Affourtit, Matthias H Tschöp, Martin Jastroch
In pancreatic beta cells, mitochondrial bioenergetics control glucose-stimulated insulin secretion (GSIS). Mitochondrial dynamics are generally associated with quality control, maintaining the functionality of bioenergetics. By acute pharmacological inhibition of mitochondrial fission protein Drp1, we here demonstrate that mitochondrial fission is necessary for GSIS in mouse and human islets. We confirm that genetic silencing of Drp1 increases mitochondrial proton leak in MIN6 cells. However, our comprehensive analysis of pancreatic islet bioenergetics reveals that Drp1 does not control insulin secretion via its effect on proton leak but instead via modulation of glucose-fuelled respiration...
February 7, 2017: Diabetes
Jochem M G Evers, Roman A Laskowski, Marta Bertolli, Jill Clayton-Smith, Charu Deshpande, Jacqueline Eason, Frances Elmslie, Frances Flinter, Carol Gardiner, Jane A Hurst, Helen Kingston, Usha Kini, Anne K Lampe, Derek Lim, Alison Male, Swati Naik, Michael J Parker, Sue Price, Leema Robert, Ajoy Sarkar, Volker Straub, Geoff Woods, Janet M Thornton, Caroline F Wright
Haploinsufficiency in DYRK1A is associated with a recognizable developmental syndrome, though the mechanism of action of pathogenic missense mutations is currently unclear. Here we present 19 de novo mutations in this gene, including five missense mutations, identified by the Deciphering Developmental Disorder study. Protein structural analysis reveals that the missense mutations are either close to the ATP or peptide binding-sites within the kinase domain, or are important for protein stability, suggesting they lead to a loss of the protein's function mechanism...
January 4, 2017: Human Molecular Genetics
J H Chong, D Mermin, J F Goussot, A Taïeb
A 3 year old girl of West African descent presented with asymptomatic skin lesions on her limbs, face, back and trunk which increased in number over a period of 1 year. She was well-thrived with no significant past medical history nor family history of atopic or autoimmune diseases. Examination showed a linear hypopigmented band in a blaschkoid distribution with a few scattered papules extending from her distal left arm to her anterior shoulder and chest (Fig. 1). There were also linear depigmented streaks which developed after trauma and depigmented macules on her limbs, back, face and trunk (Fig...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Fatima Murtaza, Abdur Rahim Bangash, Arshad Khushdil, Sahibzada Mahmood Noor
OBJECTIVE: To compare the efficacy in terms of reduction in melasma area and severity index (MASI) score by more than 10 of a combination of 20% trichloro-acetic acid peel plus 5% topical magnesium ascorbyl phosphate versus 20% trichloroacetic acid peel alone in the treatment of epidermal melasma. STUDY DESIGN: Randomized controlled trial. PLACE AND DURATION OF STUDY: Department of Dermatology, Lady Reading Hospital (LRH), Peshawar, from May 2012 to May 2013...
July 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Tatsuya Ide, Natsumi Kanzaki, Wakako Ohmura, Kimiko Okabe
A rapid and technically simple molecular detection method was developed for the western drywood termite, Incisitermes minor (Hagen), which is among the most harmful pests of wooden architectures. The method features DNA extraction from fecal pellets and species-specific loop-mediated isothermal amplification (LAMP) of DNA. As drywood termites have low moisture requirements, they easily infest artificial wooden products, and are likely to spread by human transportation of infested wood and wooden products. Rapid detection and accurate identification are essential tools for termite eradication at new sites of introduction...
July 29, 2016: Journal of Economic Entomology
Wendy Wood, Jenna L Lampe, Christina A Logan, Amy R Metcalfe, Beth E Hoesly
BACKGROUND: There is a need for a conceptual practice model that explicates ecological complexities involved in using occupation to optimize the quality of life of institutionalized people with dementia. PURPOSE: This study aimed to prepare the Lived Environment Life Quality Model, a dementia-specific conceptual practice model of occupational therapy in institutional facilities, for publication and application to practice. METHOD: Interviews and focus groups with six expert occupational therapists were subjected to qualitative content analysis to confirm, disconfirm, and further develop the model...
July 18, 2016: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
Mei-fen Shen, Xi-guang Feng, Ning-bo Huang, Yun Zhang, Ming-shou Wu, Jing Song, Meng-tao Xiong, Li-fang Wang
OBJECTIVE: To understand the Oncomelania hupensis distribution and infection status in the schistosomiasis surveillance sites of Yunnan Province, so as to provide the evidence for making the control and prevention measures. METHODS: Eighteen administrative villages were selected as the surveillance sites where the schistosomiasis endemic was serious in 18 epidemic counties, one village for one county. The snail status was investigated with the systematic sampling and environmental sampling methods, and the infection status of the snails was detected by a microscope and loop-mediated isothermal amplification (LAMP)...
February 2016: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Malcolm Pinto, Ganesh Kamath Hundi, Ramesh Marne Bhat, Nanda Kishore Bala, Sukumar Dandekeri, Jacintha Martis, Srinath M Kambil
BACKGROUND: Skin infections caused by coryneform bacteria are common dermatological conditions. However, to the best of our knowledge, no studies are available on the clinical characteristics and epidemiological features of this group of disorders as one entity from India and abroad. AIMS: To study the clinical and epidemiological features of coryneform skin infections. METHODS: A total of 75 patients presenting with clinically distinctive lesions of pitted keratolysis, erythrasma and trichobacteriosis to our hospital were included in the study...
May 2016: Indian Dermatology Online Journal
Regina M Simeone, Carrie K Shapiro-Mendoza, Dana Meaney-Delman, Emily E Petersen, Romeo R Galang, Titilope Oduyebo, Brenda Rivera-Garcia, Miguel Valencia-Prado, Kimberly B Newsome, Janice Pérez-Padilla, Tonya R Williams, Matthew Biggerstaff, Denise J Jamieson, Margaret A Honein
Zika virus is a cause of microcephaly and brain abnormalities (1), and it is the first known mosquito-borne infection to cause congenital anomalies in humans. The establishment of a comprehensive surveillance system to monitor pregnant women with Zika virus infection will provide data to further elucidate the full range of potential outcomes for fetuses and infants of mothers with asymptomatic and symptomatic Zika virus infection during pregnancy. In February 2016, Zika virus disease and congenital Zika virus infections became nationally notifiable conditions in the United States (2)...
May 27, 2016: MMWR. Morbidity and Mortality Weekly Report
Amra Osmancevic, Taye Demeke, Martin Gillstedt, Eva Angesjö, Håkan Sinclair, Gamal Abd El-Gawad, Kerstin Landin-Wilhelmsen
OBJECTIVE: There is limited information about the prevalence of vitamin D deficiency and the effects of treatment on immigrants. The effects of oral vitamin D intake and UVB treatment on vitamin D status in healthy Somali women living in Sweden were analysed. DESIGN: Two studies were carried out; a randomized, double-blind, placebo-controlled study, with oral drops of 800 IU and 1600 IU cholecalciferol and similar amounts of placebo given daily during 12 weeks and a single-blind, placebo-controlled study, using UVB (4·3-8·7 J/cm(2) ) or Woods lamp (placebo) on the upper body, or the face and hands...
October 2016: Clinical Endocrinology
Tatsuya Ide, Natsumi Kanzaki, Wakako Ohmura, Kimiko Okabe
Lyctus brunneus(Stephens) is one of the most destructive and worldwide invasive pests of seasoned woods for wooden products. This and other pestLyctusspecies have had their distribution expanded by international and domestic human transportation of infested wood and wood products. Rapid detection and accurate identification ofLyctusspecies are effective tools for helping to eradicate them in new introduction sites. The accurate species-level identification of adults requires expert knowledge about their morphology...
March 27, 2016: Journal of Economic Entomology
Antoine Cogulet, Pierre Blanchet, Véronic Landry
The photodegradation of white spruce by artificial ageing was studied by several techniques: colourimetry, FTIR-ATR and FT-Raman spectroscopy. Samples were exposed at a xenon lamp for 2000h. Two distinct colour changes were found by colourimetric analysis, yellowing and silvering. These colour modifications indicate the formation of chromophoric structures which supports previous FTIR-ATR experiments. The degradation of lignin to generate the first chromophoric group for yellowing and then the appearance of surface layer cellulose...
May 2016: Journal of Photochemistry and Photobiology. B, Biology
Brian Rinker
BACKGROUND: Skin-sparing mastectomy with immediate reconstruction can yield excellent aesthetic results, but high rates of mastectomy flap necrosis have been reported. A prospective cohort study was undertaken to compare three methods of assessing mastectomy flap viability following skin-sparing mastectomy and immediate reconstruction to determine which is most effective in reducing mastectomy flap necrosis. METHODS: The study group included 60 consecutive patients (99 breasts) undergoing skin-sparing mastectomy and immediate reconstruction with either tissue expanders (n = 39) or transverse rectus abdominis musculocutaneous flaps (n = 21)...
February 2016: Plastic and Reconstructive Surgery
Xinzhe Yu, Hengchao Li, Deliang Fu, Chen Jin, J I Li
Currently, the use of photosensitizers as tracer agents to detect lymphatic metastases is a developing area of study in the field of pancreatic cancer treatment. In the present study, deuteporfin, a novel photosensitizer, was used as a tracer agent to detect lymphatic metastases in a pancreatic cancer xenograft model. The biodistribution and pharmacokinetics of deuteporfin, following intravenous administration and injection of deuteporfin into the left rear footpad, were investigated in Sprague-Dawley rats...
September 2015: Oncology Letters
E L A Howson, B Armson, M Madi, C J Kasanga, S Kandusi, R Sallu, E Chepkwony, A Siddle, P Martin, J Wood, V Mioulet, D P King, T Lembo, S Cleaveland, V L Fowler
Accurate, timely diagnosis is essential for the control, monitoring and eradication of foot-and-mouth disease (FMD). Clinical samples from suspect cases are normally tested at reference laboratories. However, transport of samples to these centralized facilities can be a lengthy process that can impose delays on critical decision making. These concerns have motivated work to evaluate simple-to-use technologies, including molecular-based diagnostic platforms, that can be deployed closer to suspect cases of FMD...
November 30, 2015: Transboundary and Emerging Diseases
Ravali Yalamanchili, Veeranna Shastry, Jayadev Betkerur
BACKGROUND: Melasma is one of the most common and distressing pigmentary disorders presenting to dermatology clinics. The precise cause of melasma remains unknown. It is notably difficult to treat and has a tendency to relapse. Its population prevalence varies according to ethnic composition, skin phototype, and intensity of sun exposure. Due to its frequent facial involvement, the disease has an impact on the quality of life of patients. AIMS: To study the clinico-epidemiological pattern, dermascopy, wood's lamp findings and the quality of life in patients with melasma...
September 2015: Indian Journal of Dermatology
S R Park, H J Kim, H K Park, J Y Kim, N S Kim, K S Byun, T K Moon, J W Byun, J H Moon, G S Choi
BACKGROUND: Dark circles refer to a symptom that present darkness under the eyes. Because of improvement in the quality of life, the dark circles have been recognized as one of major cosmetic concerns. However, it is not easy to classify the dark circles because they have various causes. METHODS: To select suitable instruments and detailed evaluation items, the dark circles were classified according to the causes through visual assessment, Wood's lamp test, and medical history survey for 100 subjects with dark circles...
August 2016: Skin Research and Technology
C Bayerl
BACKGROUND: Homogenous pigmentation can be induced by α-melanocyte-stimulating hormone (MSH) homologues. Cosmetically inacceptable pigmentation is mostly located on the face. OBJECTIVES: Although afamelatonide is a prescription drug for the orphan disease erthropoetic protoporphyria, structurally related α-MSH derivatives are available via the internet. Preventive and therapeutical options are necessary for postinflammatory hyperpigmentation, melasma, and lentigines...
October 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Feroze Kaliyadan, Joel Kuruvilla
No abstract text is available yet for this article.
June 2015: Journal of the American Academy of Dermatology
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