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https://www.readbyqxmd.com/read/28625898/doctor-says-you-are-cured-but-you-still-feel-the-pain-borrelia-dna-persistence-in-lyme-disease
#1
REVIEW
Jorge Cervantes
Lyme disease is a zoonosis caused by infection with Borrelia burgdorferi (Bb). A great amount of research has attempted to elucidate the mechanisms by which Bb causes inflammation and chronic symptomatology in some patients. Patients often seek unconventional treatments that lack scientific evidence, as medical care is unable to effectively explain and treat their illness. Bb-DNA can persist for long periods of time in some individuals, even after antibiotic therapy. Herein, scientific rationale is presented for a new therapeutic approach against remaining bacterial DNA, and/or increasing the ability of human macrophages to remove extracellular Bb DNA...
June 15, 2017: Microbes and Infection
https://www.readbyqxmd.com/read/28622866/pathology-and-genetic-findings-in-a-rare-case-of-mycobacterium-caprae-infection-in-a-sow
#2
Benedetta Amato, Teresa Maria Capucchio, Elena Biasibetti, Elena Mangano, Beatrice Maria Boniotti, Lodovica Maria Pacciarini, Sergio Migliore, Maria Vitale, Michele Fiasconaro, Vincenzo Di Marco Lo Presti
Bovine tuberculosis, a reemerging zoonosis in diverse ecological scenarios, has been reported in the autochthonous Nebrodi black pig breed population used for meat production in Italy. During a routine abattoir inspection in 2013, 24 of 299 carcasses (8%) of Nebrodi black pigs presented tuberculosis-like lesions at pathologic examination. Mycobacterium bovis was isolated from 23 animals and M. caprae from a 3-year-old sow. The sow showed severe diffuse lesions involving the visceral organs, right coxofemoral joint, and mammary glands...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28617964/prevalence-and-genetic-features-of-rabbit-hepatitis-e-virus-in-korea
#3
Hee-Seop Ahn, Byung-Joo Park, Sang-Hoon Han, Yong-Hyun Kim, Dong-Hwi Kim, Bo-Sook Kim, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, In-Soo Choi
Hepatitis caused by hepatitis E virus (HEV) is a public health concern worldwide. HEV strains have been isolated from several animal species, some of which induce zoonosis. Recently, the isolation of HEV from rabbits was reported. Here, the partial capsid gene (320 bp) of HEV was detected in rabbit feces via reverse transcriptase-polymerase chain reaction (RT-PCR). Rabbit HEV was found in two of six rabbit farms and 17 of 264 rabbit fecal samples (6.4%). A phylogenetic analysis of the partial capsid gene classified the 17 HEV isolates into the putative rabbit HEV clade...
June 15, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28617170/adherence-of-heart-transplant-recipients-to-prescribed-medication-and-recommended-lifestyle-habits
#4
Y Brocks, A Zittermann, D Grisse, G Schmid-Ott, S Stock-Gießendanner, U Schulz, J Brakhage, A Benkler, J Gummert, Katharina Tigges-Limmer
INTRODUCTION: Nonadherence may cause severe health problems in heart transplant (HTx) recipients. RESEARCH QUESTIONS: The present study aimed to investigate adherence to prescribed medication and recommended lifestyle habits in post-HTx patients and to assess associations between adherence, quality of life (QOL), and psychological well-being. DESIGN: A questionnaire package was sent to all HTx patients from our clinic (n = 858) to answer questions anonymously on medication adherence, dietary recommendations (avoidance of raw animal products and ice cream), pet keeping (risk of zoonosis), anxiety and depression, QOL, and posttraumatic stress disorders...
June 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/28616481/evidence-of-exposure-to-rickettsia-felis-in-australian-patients
#5
Yen Thon Teoh, Sze Fui Hii, Stephen Graves, Robert Rees, John Stenos, Rebecca J Traub
Rickettsia felis is an emerging zoonosis, causing flea-borne spotted fever (FBSF). Serological diagnosis is typically confounded by cross-reactivity with typhus group rickettsiae and prior to the development of specific serological methods, cases of FBSF in Australia were misdiagnosed. Patient sera tested between August 2010 and December 2013 and known to be seropositive to R. typhi by immunofluorescence antibody testing (IFAT) were subsequently retested against R. felis using an R. felis-specific IFAT. Sera of 49 patients were of a sufficient quality to be included in re-analysis...
December 2016: One Health
https://www.readbyqxmd.com/read/28615865/epidemiological-studies-on-trichinellosis-in-pigs-sus-scofa-in-india
#6
Pranita Konwar, Balbir Bagicha Singh, Jatinder Paul Singh Gill
The present study was conducted to determine the prevalence of trichinellosis in domestic pigs (Sus scrofa) in India. A total of 319 tissue and 279 serum samples were collected from 279 slaughter pigs. The samples were collected from small slaughter shops located in Assam, Chandigarh (Union territory), Punjab and Uttarakhand states of the country. The presence of Trichinella spp. antibodies in serum was determined using a commercially available enzyme-linked immunosorbent assay (ELISA) kit and tissue samples were digested using the OIE recommended pepsin-HCl digestion method...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28613410/a-case-of-q-fever-after-liver-transplantation
#7
Lindsay A Petty, Helen S Te, Kenneth Pursell
Coxiella burnetii, the causative agent of Q fever, is a zoonosis that causes both acute and chronic disease in humans. Few cases have been reported in solid organ transplants, and this case highlights the need to include Q fever in the differential diagnosis for fever of unknown origin in solid organ transplant hosts. This article is protected by copyright. All rights reserved.
June 14, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28611756/pathogenic-leptospira-secreted-proteases-target-the-membrane-attack-complex-a-potential-role-for-thermolysin-in-complement-inhibition
#8
Thais A Amamura, Tatiana R Fraga, Sílvio A Vasconcellos, Angela S Barbosa, Lourdes Isaac
Leptospirosis is a zoonosis caused by spirochetes from the genus Leptospira. This disease is common in tropical and subtropical areas, constituting a serious public health problem. Pathogenic Leptospira have the ability to escape the human Complement System, being able to survive when in contact with normal human serum. In a previous study, our group demonstrated that supernatants of pathogenic Leptospira (SPL) inhibit the three activation pathways of the Complement System. This inhibition can be directly correlated with the activity of secreted proteases, which cleave the Complement molecules C3, Factor B (Alternative Pathway), C4 and C2 (Classical and Lectin Pathways)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28607116/elimination-of-babesia-microti-is-dependent-on-intraerythrocytic-killing-and-cd4-t-cells
#9
Sini Skariah, Paul Arnaboldi, Raymond J Dattwyler, Ali A Sultan, Corey Gaylets, Odaelys Walwyn, Hannah Mulhall, Xia Wu, Soha R Dargham, Dana G Mordue
Babesiosis is a tick-borne zoonosis caused by protozoans of the genus Babesia, apicomplexan parasites that replicate within erythrocytes. However, unlike related Plasmodium species, the pathogenesis of Babesia infection remains poorly understood. The primary etiological agent of babesiosis in the United States is B. microti. In healthy individuals, tick-transmitted infection with Babesia causes no specific clinical manifestations, with many having no symptoms at all. However, even in asymptomatic people, a Babesia carriage state can be established that can last up to a year or more...
June 12, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28606444/comparative-mitochondrial-genomics-among-spirometra-cestoda-diphyllobothriidae-and-the-molecular-phylogeny-of-related-tapeworms
#10
Xi Zhang, Jiang Yang Duan, Ya Li Shi, Peng Jiang, De Jun Zeng, Zhong Quan Wang, Jing Cui
The larva of Spirometra erinaceieuropaei can parasitize humans, causing a serious parasitic zoonosis known as sparganosis. Although it is medically important, our knowledge about the phylogenetic position of S. erinaceieuropaei and its evolutionary history is fragmentary. In this study, complete mitochondrial (mt) genomes of 4 geographically distinct isolates of S. erinaceieuropaei spargana collected from 4 frog hosts (Hylarana guentheri, Rana nigromaculata, R. rugulosa, R. temporaria) were characterized using an Illumina sequencing platform...
June 9, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28604247/brucella-central-carbon-metabolism-an-update
#11
T Barbier, A Zúñiga-Ripa, S Moussa, H Plovier, J F Sternon, L Lázaro-Antón, R Conde-Álvarez, X De Bolle, M Iriarte, I Moriyón, J J Letesson
The brucellae are facultative intracellular pathogens causing brucellosis, an important zoonosis. Here, we review the nutritional, genetic, proteomic and transcriptomic studies on Brucella carbon uptake and central metabolism, information that is needed for a better understanding of Brucella virulence. There is no uniform picture across species but the studies suggest primary and/or secondary transporters for unknown carbohydrates, lactate, glycerol phosphate, erythritol, xylose, ribose, glucose and glucose/galactose, and routes for their incorporation to central metabolism, including an erythritol pathway feeding the pentose phosphate cycle...
June 12, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28602839/epidemiology-of-brucellosis-in-iran-a-comprehensive-systematic-review-and-meta-analysis-study
#12
REVIEW
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucellosis is still one of the most challenging issues for health and the economy in many developing countries such as Iran. Considering the high prevalence of brucellosis, the aim of the current study was to systematically review published data about the annual incidence rate of this infection from different parts of Iran and provide an overall relative frequency (RF) for Iran using meta-analysis. We searched several databases including PubMed, ISI Web of Science, Scopus, google scholar, IranMedex and Iranian Scientific Information Database (SID) by using the following keywords: "Brucella", "Brucellosis", "Malta fever", "Mediterranean fever", "undulant fever", "zoonosis" and "Iran" in Title/Abstract/Keywords fields...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28602837/a-review-on-epidemiology-global-prevalence-and-economical-losses-of-fasciolosis-in-ruminants
#13
REVIEW
Khalid Mehmood, Hui Zhang, Ahmad Jawad Sabir, Rao Zahid Abbas, Muhammad Ijaz, Aneela Zameer Durrani, Muhammad Hassan Saleem, Mujeeb Ur Rehman, Muhammad Kashif Iqbal, Yajing Wang, Hafiz Ishfaq Ahmad, Tariq Abbas, Riaz Hussain, Muhammad Taslim Ghori, Sadaqat Ali, Aman Ullah Khan, Jiakui Li
Fasciolosis is an important plant borne trematode zoonosis in ruminants caused by the Fasciola hepatica and Fasciola gigentica, It is classified as a neglected tropical disease and found in more than 50 countries especially where sheep and cattle are reared. Fasciolosis is a serious animal health problems in many rural and urban areas of world, causing significant financial losses due to decrease in production and viscera condemnation in animals. Accurate diagnosis of fasciolosis is always remained a challenging task for the field practitioners...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28601495/structural-and-enzymatic-characterization-of-a-camp-dependent-diguanylate-cyclase-from-pathogenic-leptospira-species
#14
Fernanda Nogales da Costa Vasconcelos, Nikolas Koshiyama Maciel, Denize Cristina Favaro, Luciana Coutinho de Oliveira, Angela Silva Barbosa, Roberto Kopke Salinas, Robson Francisco de Souza, Chuck Shaker Farah, Cristiane Rodrigues Guzzo
Leptospira interrogans serovar Copenhageni is a human pathogen that causes leptospirosis, a worldwide zoonosis. The L. interrogans genome codes for a wide array of potential diguanylate cyclase enzymes with characteristic GGDEF domains capable of synthesizing the cyclic dinucleotide c-di-GMP, known to regulate transitions between different cellular behavioural states in bacteria. Among such enzymes, LIC13137 (Lcd1), which has an N-terminal GAF domain and a C-terminal GGDEF domain, is notable for having close orthologs present only in pathogenic Leptospira species...
June 7, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28593700/the-one-past-health-workshop-connecting-ancient-dna-and-zoonosis-research
#15
Sébastien Calvignac-Spencer, Tobias L Lenz
No abstract text is available yet for this article.
June 8, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/28591267/the-performance-of-serological-tests-for-leishmania-infantum-infection-screening-in-dogs-depends-on-the-prevalence-of-the-disease
#16
Ivete Lopes de Mendonça, Joilson Ferreira Batista, Henk Schallig, Maria do Socorro Pires E Cruz, Diego Peres Alonso, Paulo Eduardo Martins Ribolla, Dorcas Lamounier Costa, Carlos Henrique Nery Costa
Dogs are considered the main reservoir of Leishmania infantum. This protozoan causes visceral leishmaniasis (VL), an uncontrolled urban zoonosis in Brazil. Serological tests and polymerase chain reaction (PCR) on peripheral blood were performed to identify infected dogs in scenarios of higher and lower prevalence of the disease (Teresina and Vitória). One-hundred infected and 57 non-infected animals from Teresina and 100 non-infected animals from Vitória were studied. Animal selection was not dependent on previous serology...
June 1, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28589871/prevalence-of-cystic-echinococcosis-in-iran-a-systematic-review-and-meta-analysis
#17
H R Khalkhali, M Foroutan, S Khademvatan, H Majidiani, S Aryamand, P Khezri, A Aminpour
As a significant zoonosis, cystic echinococcosis (CE) is endemic in some parts of the world, such as the Middle East. There are studies on the prevalence of this infection in animal and human reservoirs in Iran; hence, we conducted this meta-analysis to elucidate the prevalence of CE in Iran. English (PubMed, Scopus, Web of Science, Science Direct and Google Scholar) and Persian (Magiran, Iran Medex, Iran Doc and SID) databases were explored. In the case of definitive, animal and human intermediate hosts, 37, 90 and 33 studies, respectively, have been included in the current review from January 1990 to December 2015...
June 7, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28585078/associations-between-fasciolosis-and-milk-production-and-the-impact-of-anthelmintic-treatment-in-dairy-herds
#18
Kerstin Köstenberger, Alexander Tichy, Karl Bauer, Peter Pless, Thomas Wittek
Liver fluke is a ubiquitous parasite that causes extensive production losses in cattle and is a zoonosis. The aims of this study were to determine the prevalence of fasciolosis in 178 dairy cattle herds in Styria (federal state of Austria) and its influence on production, to detect the risk factors for infection, and to explore effective strategies in management and control. A questionnaire on farm management, prophylaxis, and therapy was developed and applied. Furthermore, production parameters (milk yield, milk protein content, butter fat content, non-return rate 90, calving to conception interval, service period) were recorded for 2014 and 2015, and a commercial ELISA for detection of Fasciola hepatica antibodies was applied in bulk tank milk in March 2014 and March 2015...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28578732/thirty-years-of-human-infections-caused-by-yersinia-enterocolitica-in-northern-spain-1985-2014
#19
J M Marimon, R Figueroa, P Idigoras, M Gomariz, M Alkorta, G Cilla, E Pérez-Trallero
Yersinia enterocolitica infection is a zoonosis with worldwide distribution, gastroenteritis being by far the most common clinical manifestation of human infection. In Gipuzkoa, northern Spain, human Y. enterocolitica infections increased from the mid-1980s to the beginning of the 21st century (from 7·9 to 23·2 annual episodes per 100 000 population) to decrease to 7·2 annual episodes per 100 000 population in the last years of the study. The hospital admission rate due to yersiniosis during the last 15 years of the study was 7·3%...
June 5, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28572804/serum-cytokine-profiles-differentiating-hemorrhagic-fever-with-renal-syndrome-and-hantavirus-pulmonary-syndrome
#20
Svetlana F Khaiboullina, Silvana Levis, Sergey P Morzunov, Ekaterina V Martynova, Vladimir A Anokhin, Oleg A Gusev, Stephen C St Jeor, Vincent C Lombardi, Albert A Rizvanov
Hantavirus infection is an acute zoonosis that clinically manifests in two primary forms, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS is endemic in Europe and Russia, where the mild form of the disease is prevalent in the Tatarstan region. HPS is endemic in Argentina, as well as other countries of North and South American. HFRS and HPS are usually acquired via the upper respiratory tract by inhalation of virus-contaminated aerosol. Although the pathogenesis of HFRS and HPS remains largely unknown, postmortem tissue studies have identified endothelial cells as the primary target of infection...
2017: Frontiers in Immunology
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