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https://www.readbyqxmd.com/read/27930385/questions-regarding-statistical-inferences-quality-of-life-and-conclusions-from-the-cobra-study
#1
David Macarios, Ronald P Silverman
No abstract text is available yet for this article.
December 7, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27914385/beamforming-pointing-error-of-a-triaxial-velocity-sensor-under-gain-uncertainties
#2
Tsair-Chuan Lin, Kainam Thomas Wong, Macario O Cordel, Joel Paz Ilao
A "triaxial velocity sensor" consists of three uniaxial velocity sensors, which are nominally identical, orthogonally oriented among themselves, and co-centered at one point in space. A triaxial velocity sensor measures the acoustic particle velocity vector, by its three Cartesian components, individually component-by-component, thereby offering azimuth-elevation two-dimensional spatial directivity, despite the physical compactness that comes with the collocation of its three components. This sensing system's azimuth-elevation beam-pattern has been much analyzed in the open literature, but only for an idealized case of the three uniaxial velocity sensors being exactly identical in gain...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27875929/introducing-a-new-concept-in-obstructive-sleep-apnea-the-continuum-of-treatment
#3
Victor Certal, Macario Camacho, Sungjin A Song, Robson Capasso
No abstract text is available yet for this article.
November 22, 2016: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/27864177/the-histone-deacetylase-hda-2-regulates-growth-conidiation-blue-light-perception-and-oxidative-stress-responses-in-trichoderma-atroviride
#4
Macario Osorio-Concepción, Gema Rosa Cristóbal Mondragón, Braulio Gutiérrez-Medina, Sergio Casas-Flores
: Fungal blue-light photoreceptors have been proposed as integrators of light and oxidative stress. However, additional elements participating in the integrative pathway remain to be identified. In Trichoderma atroviride, the blue-light receptor proteins BLR-1 and -2 are known to regulate gene transcription, mycelial growth and asexual development upon illumination, and recent global transcriptional analysis revealed that the histone deacetylase encoding gene hda-2 is induced by light...
November 18, 2016: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/27860021/detection-of-leishmania-amazonensis-and-leishmania-braziliensis-in-culicoides-diptera-ceratopogonidae-in-an-endemic-area-of-cutaneous-leishmaniasis-in-the-brazilian-amazonia
#5
José Manuel Macário Rebêlo, Bruno Leite Rodrigues, Maria da Conceição Abreu Bandeira, Jorge Luiz Pinto Moraes, Raquel Silva Fonteles, Silma Regina Ferreira Pereira
Biting midges in the genus Culicoides act as vectors of arboviruses throughout the world and as vectors of filariasis in Latin America, the Caribbean, and parts of Africa. Although Culicoides spp. are currently not considered to be vectors of Leishmania protozoa, the high abundance of biting midges in areas with active cutaneous leishmaniasis transmission points to the possibility of Culicoides infection by these pathogens. We used PCR to test captured Culicoides species for natural infection with Leishmania spp...
December 2016: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/27843736/does-faculty-follow-the-recommended-structure-for-a-new-classroom-based-daily-formal-teaching-session-for-anesthesia-residents
#6
Anjum Anwar, Pedro Tanaka, Matias V Madsen, Alex Macario
BACKGROUND:  A newly implemented 15-minute classroom-based, formal teaching session for anesthesia residents is given three times daily by the same faculty. The faculty member was provided a suggested template for the presentation. The template structure was developed by a group of residents and faculty to include best teaching practices. The goal of the current study was to measure how frequently the faculty teaching these sessions followed the template. METHODS: From February 20, 2015 to February 6, 2016, a research assistant trained in education mapped a total of 48 teaching sessions to determine how frequently the teaching sessions included each of the elements in the recommended template structure...
October 6, 2016: Curēus
https://www.readbyqxmd.com/read/27836734/doxorubicin-anti-tumor-mechanisms-include-hsp60-post-translational-modifications-leading-to-the-hsp60-p53-complex-dissociation-and-instauration-of-replicative-senescence
#7
Antonella Marino Gammazza, Claudia Campanella, Rosario Barone, Celeste Caruso Bavisotto, Magdalena Gorska, Michal Wozniak, Francesco Carini, Francesco Cappello, Antonella D'Anneo, Marianna Lauricella, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Valentina Di Felice
The chaperone Hsp60 is pro-carcinogenic in certain tumor types by interfering with apoptosis and with tumor cell death. In these tumors, it is not yet known whether doxorubicin anti-tumor effects include a blockage of the pro-carcinogenic action of Hsp60. We found a doxorubicin dose-dependent viability reduction in a human lung mucoepidermoid cell line that was paralleled by the appearance of cell senescence markers. Concomitantly, intracellular Hsp60 levels decreased while its acetylation levels increased...
January 28, 2017: Cancer Letters
https://www.readbyqxmd.com/read/27833866/long-term-outcomes-of-radiofrequency-ablation-of-the-inferior-turbinates
#8
Casey Means, Macario Camacho, Robson Capasso
Radiofrequency ablation of the inferior turbinates (RFAIT) is a minimally invasive surgical technique that reduces turbinate size and decreases nasal obstruction. Few studies have assessed long-term outcomes of this procedure using standardized, symptom-specific evaluation instruments. The primary aim of this study is to assess the long-term effectiveness of RFAIT using a standardized, symptom-specific evaluation instrument. An additional outcome evaluated is the effect of RFAIT on therapeutic CPAP pressures in centimetres of water pressure (cwp) and overall CPAP use...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27832139/a-subpopulation-of-the-k562-cells-are-killed-by-curcumin-treatment-after-g2-m-arrest-and-mitotic-catastrophe
#9
Macario Martinez-Castillo, Raul Bonilla-Moreno, Leticia Aleman-Lazarini, Marco Antonio Meraz-Rios, Lorena Orozco, Leticia Cedillo-Barron, Emilio J Cordova, Nicolas Villegas-Sepulveda
Curcumin is extensively investigated as a good chemo-preventive agent in the development of many cancers and particularly in leukemia, including treatment of chronic myelogenous leukemia and it has been proposed as an adjuvant for leukemia therapies. Human chronic myeloid leukemia cells (K562), were treated with 20 μM of curcumin, and we found that a subpopulation of these cells were arrested and accumulate in the G2/M phase of the cell cycle. Characterization of this cell subpopulation showed that the arrested cells presented nuclear morphology changes resembling those described for mitotic catastrophe...
2016: PloS One
https://www.readbyqxmd.com/read/27796040/rapid-maxillary-expansion-for-pediatric-obstructive-sleep-apnea-a-systematic-review-and-meta-analysis
#10
Macario Camacho, Edward T Chang, Sungjin A Song, Jose Abdullatif, Soroush Zaghi, Paola Pirelli, Victor Certal, Christian Guilleminault
OBJECTIVES/HYPOTHESIS: To perform a systematic review with meta-analysis for sleep study outcomes in children who have undergone rapid maxillary expansion (RME) as treatment for obstructive sleep apnea (OSA). DATA SOURCES: PubMed/MEDLINE and eight additional databases. REVIEW METHODS: Three authors independently and systematically reviewed the international literature through February 21, 2016. RESULTS: Seventeen studies reported outcomes for 314 children (7...
October 31, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27795710/treatment-of-snoring-with-a-nasopharyngeal-airway-tube
#11
Macario Camacho, Edward T Chang, Camilo Fernandez-Salvador, Robson Capasso
Objective. To study the feasibility of a standard nasopharyngeal airway tube (NPAT) as treatment for snoring. Methods. An obese 35-year-old man, who is a chronic, heroic snorer, used NPATs while (1) the patient's bedpartner scored the snoring and (2) the patient recorded himself with the smartphone snoring app "Quit Snoring." Baseline snoring was 8-10/10 (10 = snoring that could be heard through a closed door and interrupted the bedpartner's sleep to the point where they would sometimes have to sleep separately) and 60-200 snores/hr...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27777686/is-it-inappropriate-for-attendings-and-residents-to-be-friends-on-facebook-and-other-social-media-accounts
#12
EDITORIAL
Macario Camacho, Justin M Wei, Edward T Chang
No abstract text is available yet for this article.
October 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/27765079/effect-of-dietary-lysine-on-performance-and-expression-of-electron-transport-chain-genes-in-the-pectoralis-major-muscle-of-broilers
#13
C O Brito, J L L Dutra, T N Dias, L T Barbosa, C S Nascimento, A P G Pinto, L F T Albino, R P M Fernandes, M S Macário, J S Melo
The aim of this study was to evaluate the effect of dietary lysine on performance, protein deposition and respiratory chain gene expression in male broilers. A total of 252 Cobb 500 broilers were distributed, in a completely randomized design, into four treatments with seven replicates of nine birds per experimental unit. Experimental treatments consisted of diets based on corn and soybean meal, with four levels of digestible lysine: 1.016%, 1.099%, 1.182% and 1.265%. The increase in the level of digestible lysine in the diet provided higher weight gains, feed efficiency and body protein deposition...
October 21, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27756633/identification-of-a-novel-deletion-in-surf1-gene-heterogeneity-in-leigh-syndrome-with-cox-deficiency
#14
Carolina Ribeiro, Maria do Carmo Macário, Ana Teresa Viegas, João Pratas, Maria João Santos, Marta Simões, Cândida Mendes, Mafalda Bacalhau, Paula Garcia, Luísa Diogo, Manuela Grazina
Leigh syndrome (LS) is a rare, progressive neurodegenerative mitochondrial disorder of infancy. It is a genetically heterogeneous disease. The mutations in SURF1 gene are the most frequently known cause. Here two cases of LS likely caused by SURF1 gene variants are reported: a 39-year-old male patient with a novel homozygous deletion (c.-11_13del), and a case of a 6-year-old boy with the same deletion and a nonsense mutation (c.868dupT), both in heterozygosity. Blue native PAGE showed absence of assembled complex IV...
November 2016: Mitochondrion
https://www.readbyqxmd.com/read/27733351/a-comparison-of-two-fat-grafting-methods-on-operating-room-efficiency-and-costs
#15
Allen Gabriel, G Patrick Maxwell, Leah Griffin, Manish C Champaneria, Mousam Parekh, David Macarios
BACKGROUND: Centrifugation (Cf) is a common method of fat processing but may be time consuming, especially when processing large volumes. OBJECTIVES: To determine the effects on fat grafting time, volume efficiency, reoperations, and complication rates of Cf vs an autologous fat processing system (Rv) that incorporates fat harvesting and processing in a single unit. METHODS: We performed a retrospective cohort study of consecutive patients who underwent autologous fat grafting during reconstructive breast surgery with Rv or Cf...
October 11, 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27622095/the-safety-effectiveness-and-efficiency-of-autologous-fat-grafting-in-breast-surgery
#16
REVIEW
Scott L Spear, Courtney N Coles, Braden K Leung, Matthew Gitlin, Mousam Parekh, David Macarios
BACKGROUND: For years, the safety and effectiveness of autologous fat grafting (AFG) for breast reconstruction have been in question, with particular concern over fat necrosis, calcifications, cyst formation, and interfering with the detection of breast cancer. However, increasing evidence suggests that the complication rates and clinical results are generally acceptable to both clinicians and patients. The emerging challenge is the numerous AFG techniques and systems, where there are limited knowledge and data...
August 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27596329/evaluation-of-acute-toxicity-genotoxicity-and-inhibitory-effect-on-acute-inflammation-of-an-ethanol-extract-of-morus-alba-l-moraceae-in-mice
#17
Alisson Macário de Oliveira, Matheus Ferreira do Nascimento, Magda Rhayanny Assunção Ferreira, Danielle Feijó de Moura, Talita Giselly Dos Santos Souza, Gabriela Cavalcante da Silva, Eduardo Henrique da Silva Ramos, Patrícia Maria Guedes Paiva, Paloma Lys de Medeiros, Teresinha Gonçalves da Silva, Luiz Alberto Lira Soares, Cristiano Aparecido Chagas, Ivone Antônia de Souza, Thiago Henrique Napoleão
ETHNOPHARMACOLOGICAL RELEVANCE: Morus alba L. (white mulberry) is used in traditional medicine worldwide, including Brazil. The leaves of this plant are used to treat inflammatory disorders. Universal interest in this plant necessitates studies on the toxicological safety and scientific substantiation of the medicinal properties of M. alba. In previous work, we investigated the acute toxicity of orally administered M. alba ethanol extract in mice. AIM OF THE STUDY: This work was designed to investigate the ethanol extract obtained from M...
September 2, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27546467/genial-tubercle-advancement-and-genioplasty-for-obstructive-sleep-apnea-a-systematic-review-and-meta-analysis
#18
Sungjin A Song, Edward T Chang, Victor Certal, Michael Del Do, Soroush Zaghi, Stanley Yung Liu, Robson Capasso, Macario Camacho
OBJECTIVE: To perform a systematic review and meta-analysis for studies evaluating genioplasty alone, genial tubercle advancement (GTA) alone, and GTA with hyoid surgery (GTA-HS) to treat obstructive sleep apnea (OSA). DATA SOURCES: Ten databases. REVIEW METHODS: Three authors searched through November 15, 2015. RESULTS: 1,207 studies were screened; 69 were downloaded; and 13 studies met inclusion criteria. A total of 111 patients were included, with 27 standard genioplasty, 10 modified genioplasty, 24 GTA, and 50 GTA-HS patients...
August 22, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27542939/predictors-of-first-line-treatment-persistence-in-a-portuguese-cohort-of-relapsing-remitting-multiple-sclerosis
#19
Inês Correia, Inês Brás Marques, Mário Sousa, Sónia Batista, Rogério Ferreira, Carla Nunes, Carmo Macário, Luís Cunha, Lívia Sousa
Treatment persistence in first-line injectable disease-modifying therapies (DMT) for relapsing-remitting multiple sclerosis (RRMS) is an important indicator of effectiveness. Identifying predictors of treatment discontinuation is important as there are other therapies currently available and a growing range of emerging drugs. We report a retrospective study of RRMS and clinically isolated syndrome patients followed in a University Hospital during a 13-year period with the objective of identifying predictors of treatment persistence...
November 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27491302/quantitative-patterns-of-hsps-in-tubular-adenoma-compared-with-normal-and-tumor-tissues-reveal-the-value-of-hsp10-and-hsp60-in-early-diagnosis-of-large-bowel-cancer
#20
Francesca Rappa, Alessandro Pitruzzella, Antonella Marino Gammazza, Rosario Barone, Emanuele Mocciaro, Giovanni Tomasello, Francesco Carini, Felicia Farina, Giovanni Zummo, Everly Conway de Macario, Alberto Jl Macario, Francesco Cappello
Large bowel carcinogenesis involves accumulation of genetic alterations leading to transformation of normal mucosa into dysplasia and, lastly, adenocarcinoma. It is pertinent to elucidate the molecular changes occurring in the pre-neoplastic lesions to facilitate early diagnosis and treatment. Heat shock proteins (Hsps), many of which are molecular chaperones, are implicated in carcinogenesis, and their variations with tumor progression encourage their study as biomarkers. There are many reports on Hsps and cancer but none to our knowledge on their systematic quantification in pre-neoplastic lesions of the large bowel...
September 2016: Cell Stress & Chaperones
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