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https://www.readbyqxmd.com/read/29759280/overlapping-surgery-a-case-study-in-operating-room-throughput-and-efficiency
#1
REVIEW
Amanda J Morris, Joseph A Sanford, Edward J Damrose, Samuel H Wald, Bassam Kadry, Alex Macario
A keystone of operating room (OR) management is proper OR allocation to optimize access, safety, efficiency, and throughput. Access is important to surgeons, and overlapping surgery may increase patient access to surgeons with specialized skill sets and facilitate the training of medical students, residents, and fellows. Overlapping surgery is commonly performed in academic medical centers, although recent public scrutiny has raised debate about its safety, necessitating monitoring. This article introduces a system to monitor overlapping surgery, providing a surgeon-specific Key Performance Indicator, and discusses overlapping surgery as an approach toward OR management goals of efficiency and throughput...
June 2018: Anesthesiology Clinics
https://www.readbyqxmd.com/read/29755518/double-barrel-nasal-trumpets-to-prevent-upper-airway-obstruction-after-nasal-and-non-nasal-surgery
#2
Macario Camacho, Justin M Wei, Lauren K Reckley, Sungjin A Song
Objectives: During anesthesia emergence, patients are extubated and the upper airway can become vulnerable to obstruction. Nasal trumpets can help prevent obstruction. However, we have found no manuscript describing how to place nasal trumpets after nasal surgery (septoplasties or septorhinoplasties), likely because (1) the lack of space with nasal splints in place and (2) surgeons may fear that removing the trumpets could displace the splints. The objective of this manuscript is to describe how to place nasal trumpets even with nasal splints in place...
2018: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/29754977/use-of-the-long-term-quality-of-life-assessment-in-the-decision-to-indicate-surgery-in-patients-with-chronic-rhinosinusitis
#3
Pablo Pinillos Marambaia, Manuela Garcia Lima, Hélder Macario, Amaury de Machado Gomes, Leonado Marques Gomes, Melina Pinillos Marambaia, Otávio Marambaia Dos Santos
INTRODUCTION: Quality-of-life questionnaires have been used to support decision-making in patients with chronic rhinosinusitis in the past decade. The choice of treatment in practice, however, also considers the patient's decision. OBJECTIVE: To assess the long-term quality of life of patients with chronic rhinosinusitis who decided to avoid surgery. METHODS: This is a prospective longitudinal study with a group of patients with chronic rhinosinusitis, with and without indication for surgery, with application of the questionnaire SNOT-22 in two periods: between 2011 and 2012 and between June and August 2016, via email...
April 22, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29747717/food-environment-social-deprivation-and-obesity-among-students-from-brazilian-public-schools
#4
Maíra Macário de Assis, Maria Alvim Leite, Ariene Silva do Carmo, Amanda Cristina de Souza Andrade, Milene Cristine Pessoa, Michele Pereira Netto, Ana Paula Carlos Cândido, Larissa Loures Mendes
OBJECTIVE: To investigate the relationship between social deprivation and the food environment. Furthermore, to evaluate if the food environment is associated with the prevalence of obesity among students in Brazilian public schools. DESIGN: Cross-sectional. For the classification of obesity, weight and height were measured, and the cut-off point of BMI-for-age Z-score >+2 was adopted. Social deprivation level was determined from the Health Vulnerability Index (HVI)...
May 11, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29710725/prevalence-of-dementia-and-associated-risk-factors-a-population-based-study-in-the-philippines
#5
Jacqueline Dominguez, Ma Fe de Guzman, Macario Reandelar, Thien Kieu Thi Phung
BACKGROUND: The Philippines is experiencing rapid demographic aging and with it, the dementia epidemic. Prevalence of dementia and associated risk factors have not been studied in the Philippines. OBJECTIVES: The study aimed to provide a reliable estimate of dementia prevalence and identify associated risk factors in the Filipino population. METHODS: 1460 participants 60 years and older were randomly selected from the Marikina City's senior registry...
April 25, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29688921/development-of-an-objective-structured-clinical-examination-using-the-american-board-of-anesthesiology-content-outline-for-the-objective-structured-clinical-examination-component-of-the-applied-certification-examination
#6
Pedro Tanaka, Aileen Adriano, Lynn Ngai, Yoon Soo Park, Adrian Marty, Shin Wakatsuki, Carlos Brun, Kyle Harrison, Erin Bushell, Jakob Louis Demant Thomsen, Louise Wen, Christopher Painter, Marianne Chen, Alex Macario
The goal of this study was to use the American Board of Anesthesiology Objective Structured Clinical Examination (OSCE) content outline as a blueprint to develop and administer a 9-station mock OSCE with station-specific checklists to senior residents (n = 14). The G- and Ф-coefficient reliability estimates were 0.76 and 0.61, respectively. Residents judged the scenarios as either extremely or somewhat realistic (88%). It is feasible to develop and administer a mock OSCE with rigorous psychometric characteristics...
April 23, 2018: A&A practice
https://www.readbyqxmd.com/read/29675059/natural-history-of-treatment-emergent-central-sleep-apnea-on-positive-airway-pressure-a-systematic-review
#7
Gaurav Nigam, Muhammad Riaz, Edward T Chang, Macario Camacho
INTRODUCTION: Treatment-emergent central sleep apnea (TECSA) is observed in some patients when they are treated with positive airway pressure (PAP) after significant resolution of the preexisting obstructive events in patients with obstructive sleep apnea. The objective of this study was to systematically review the literature for studies describing the natural history of TECSA. METHODS: PubMed, Medline, Scopus, Web of Science, and Cochran Library databases were searched through June 29, 2017...
April 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29672336/cost-benefit-analysis-of-maintaining-a-fully-stocked-malignant-hyperthermia-cart-versus-an-initial-dantrolene-treatment-dose-for-maternity-units
#8
Phi T Ho, Brendan Carvalho, Eric C Sun, Alex Macario, Edward T Riley
BACKGROUND: The Malignant Hyperthermia Association of the United States recommends that dantrolene be available for administration within 10 min. One approach to dantrolene availability is a malignant hyperthermia cart, stocked with dantrolene, other drugs, and supplies. However, this may not be of cost benefit for maternity units, where triggering agents are rarely used. METHODS: The authors performed a cost-benefit analysis of maintaining a malignant hyperthermia cart versus a malignant hyperthermia cart readily available within the hospital versus an initial dantrolene dose of 250 mg, on every maternity unit in the United States...
April 19, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29670412/the-effect-of-tonsillectomy-on-obstructive-sleep-apnea-an-overview-of-systematic-reviews
#9
REVIEW
Lauren K Reckley, Camilo Fernandez-Salvador, Macario Camacho
Objective: Tonsillectomy with adenoidectomy is a combination surgery that has been used to treat pediatric obstructive sleep apnea (OSA). For adults, tonsillectomy has also been reported as a primary treatment modality when the tissue is hypertrophied. The objective of this study is to provide an overview of published systematic reviews and meta-analyses of tonsillectomy with or without adenoidectomy as used in the treatment of OSA in children and adults. Data sources: Nine databases, including PubMed/MEDLINE...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29661452/staphylococcus-infection-associated-glomerulonephritis-in-a-kidney-transplant-patient-case-report
#10
D Cascais de Sá, L Rodrigues, L Santos, C Romãozinho, F Macário, C Marinho, J Pratas, R Alves, A Figueiredo
BACKGROUND: Staphylococcus infection-associated glomerulonephritis is a rare cause of graft dysfunction in kidney transplant. Suspicion should be high in the setting of elevation of serum creatinine, active urinary sediment, with or without hypocomplementemia, and simultaneous Staphylococcus aureus infection. A kidney biopsy is usually diagnostic. CASE REPORT: A 56-year-old man, who received a kidney transplant in 1998, with basal serum creatinine of 1.2 mg/dL and normal urinary sediment, was admitted to our kidney transplantation unit with graft dysfunction and a urinary tract infection caused by S aureus with septicemia, treated with antibiotics, in the context of recently intensified immunosuppression for a primary immune thrombocytopenia diagnosed 3 weeks earlier...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29658136/predatory-journals-enough-is-enough
#11
Macario Camacho, Lauren K Reckley
No abstract text is available yet for this article.
April 15, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29626561/saline-extract-of-pilosocereus-gounellei-stem-has-antinociceptive-effect-in-mice-without-showing-acute-toxicity-and-altering-motor-coordination
#12
Alisson Macário de Oliveira, Micaelle Oliveira de Luna Freire, Wliana Alves Viturino da Silva, Magda Rhayanny Assunção Ferreira, Patrícia Maria Guedes Paiva, Luiz Alberto Lira Soares, Paloma Lys de Medeiros, Bruno de Melo Carvalho, Thiago Henrique Napoleão
People broadly use medicinal plants although their safety and efficacy are often neglected. Several Cactaceae plants are used for medicinal purposes, but Pilosocereus gounellei (xique-xique) has been little studied for their pharmacological properties. In this study, a saline extract from Pilosocereus gounellei stem was evaluated for acute toxicity, effects on motor function, and antinociceptive activity in mice. Thin-layer chromatography and high-performance liquid chromatography revealed the presence of flavonoids and reducing sugars...
June 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29616136/curcumin-differentially-affects-cell-cycle-and-cell-death-in-acute-and-chronic-myeloid-leukemia-cells
#13
Macario Martínez-Castillo, Nicolas Villegas-Sepúlveda, Marco A Meraz-Rios, Araceli Hernández-Zavala, Jaime Berumen, Mathew A Coleman, Lorena Orozco, Emilio J Cordova
Curcumin is a phytochemical with potent anti-neoplastic properties. The antitumoral effects of curcumin in cells derived from chronic or acute myeloid leukemia have been already described. However, a comparative study of the cytostatic and cytotoxic effects of curcumin on chronic and acute myeloid leukemia cells has not yet been performed. In the present study, the cellular effects of curcumin on cell lines derived from chronic or acute myeloid leukemia were examined. Dose and time-response assays were performed with curcumin on HL-60 and K562 cells...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29562268/dna-barcoding-reveals-hidden-diversity-of-sand-flies-diptera-psychodidae-at-fine-and-broad-spatial-scales-in-brazilian-endemic-regions-for-leishmaniasis
#14
Bruno Leite Rodrigues, Luís Fernando Carvalho-Costa, Israel de Souza Pinto, José Manuel Macário Rebêlo
Sand fly (Diptera: Psychodidae) taxonomy is complex and time-consuming, which hampers epidemiological efforts directed toward controlling leishmaniasis in endemic regions such as northeastern Brazil. Here, we used a fragment of the mitochondrial cytochrome c oxidase I (COI) gene to identify sand fly species in Maranhão State (northeastern Brazil) and to assess cryptic diversity occurring at different spatial scales. For this, we obtained 148 COI sequences of 15 sand fly species (10 genera) from Maranhão (fine spatial scale), and joined them to COI sequences from other Brazilian localities (distant about 2,000 km from Maranhão, broad spatial scale) available in GenBank...
March 17, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29552646/quantitative-analysis-of-the-impact-of-a-human-pathogenic-mutation-on-the-cct5-chaperonin-subunit-using-a-proxy-archaeal-ortholog
#15
Dario Spigolon, D Travis Gallagher, Adrian Velazquez-Campoy, Donatella Bulone, Jatin Narang, Pier Luigi San Biagio, Francesco Cappello, Alberto J L Macario, Everly Conway de Macario, Frank T Robb
The human chaperonin complex is a ~ 1 MDa nanomachine composed of two octameric rings formed from eight similar but non-identical subunits called CCT. Here, we are elucidating the mechanism of a heritable CCT5 subunit mutation that causes profound neuropathy in humans. In previous work, we introduced an equivalent mutation in an archaeal chaperonin that assembles into two octameric rings like in humans but in which all subunits are identical. We reported that the hexadecamer formed by the mutant subunit is unstable with impaired chaperoning functions...
December 2017: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/29538543/association-between-the-display-of-cigarette-packs-at-the-point-of-sale-and-smoking-susceptibility-among-adolescents-in-brazil
#16
Ana Luiza Curi Hallal, Andreza Madeira Macario, Roberto Hess de Souza, Antônio Fernando Boing, Lúcio Botelho, Joanna Cohen
This was a cross-sectional study aimed at determining the association between exposure to tobacco displays at the point of sale and susceptibility to smoking in schoolchildren in the 14- to 17-year age bracket. Of the participating students, 69.0%, 21.3%, and 9.7% were classified as never smokers, experimenters, and smokers, respectively. Of the participants who were classified as being exposed to smoking, 18.9% were susceptible to smoking. Of the participants who were classified as being unexposed to smoking, 12...
January 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29525140/neuromuscular-function-of-the-soft-palate-and-uvula-in-snoring-and-obstructive-sleep-apnea-a-systematic-review
#17
REVIEW
Jagatkumar A Patel, Bryan J Ray, Camilo Fernandez-Salvador, Christopher Gouveia, Soroush Zaghi, Macario Camacho
OBJECTIVE: A collapsible upper airway is a common cause of obstructive sleep apnea. The exact pathophysiology leading to a more collapsible airway is not well understood. A progressive neuropathy of the soft palate and pharyngeal dilators may be associated with the progression of snoring to OSA. The purpose of this study is to systematically review the international literature investigating the neurophysiologic changes in the soft palate and uvula that contribute to progression from snoring to OSA...
May 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29524092/the-relationship-of-the-uvula-with-snoring-and-obstructive-sleep-apnea-a-systematic-review
#18
REVIEW
Edward T Chang, Grace Baik, Carlos Torre, Scott E Brietzke, Macario Camacho
Currently, the relationship between uvula size and sleep-disordered breathing (snoring and obstructive sleep apnea) lacks data for objective interpretation. This study conducted a systematic review of the international literature for research describing the measurable characteristics of the uvula (i.e., size, length, width) and any association with snoring and obstructive sleep apnea (OSA). PubMED, Scopus, Google Scholar, Embase, and the Cochrane Library were each systematically searched from inception through November 15, 2016...
March 9, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29503823/editorial-pathologic-conditions-of-the-human-nervous-and-muscular-systems-associated-with-mutant-chaperones-molecular-and-mechanistic-aspects
#19
EDITORIAL
Alberto J L Macario, Everly Conway de Macario
No abstract text is available yet for this article.
2018: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/29484920/music-appreciation-after-cochlear-implantation-in-adult-patients-a-systematic-review
#20
Phoebe E Riley, Douglas S Ruhl, Macario Camacho, Anthony M Tolisano
Objective The cochlear implant (CI) improves quality of life for people who are severely and profoundly deafened, allowing implantees to perceive speech at levels similar to those of individuals with normal hearing. However, patients with CIs generally report a reduced appreciation of music after implantation. We aimed to systematically review the English-language literature for studies evaluating music enjoyment and perception among adult patients with CIs. Data Sources A systematic review of PubMed/MEDLINE, Scopus, Embase, and the Cochrane Library...
February 1, 2018: Otolaryngology—Head and Neck Surgery
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