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myastenia gravis classification

R Petkov, N Kŭtev, V Mladenovski, G Todorov, N Gavrilov, A Atanasov, N Goranov
OBJECTIVE: Thymectomy is considered an effective therapeutic option for patients with myasthenia gravis (MG). We reviewed our 25-years experience with surgical treatment of MG with respect to long-term results and factors affecting outcome. METHODS: Between 1978 and 2002, we performed 232 thymectomies for MG. Fifteen patients were lost to follow-up; the remaining 217 form the object of our study. 32 patients (28.4%) had thymoma. Myasthenia was graded according to a modified Osserman classification: 51 patients (23...
2004: Khirurgiia
A Szobor, A Máttyus, J Molnár
Authors review the different theoretical and practical problems of childhood and adolescent myastenia gravis, including the heterogeneous group of congenital myasthenia and the big casuistics of the literature. There are reports on 113 cases with childhood myasthenia gravis and 96 cases of adolescent myasthenia. Ratio of these forms ranged 10.76% in childhood myasthenia and 9.14% in adolescent age, resp., 19.9% of the whole patient material. A classification is given concerning juvenile myasthenia: 1. Neonatal (transitory) myasthenia...
0: Acta Paediatrica Hungarica
P Buchmann, B Bumbacher, S Geroulanos, F Largiadèr
In the management of Myastenia gravis thymectomy has gained an important position. Still in discussion is whether a transsternal approach gives a superior result to a collar approach. Between 1970 and 1986 35 patients with Myasthenia gravis underwent thymectomy, in 12 by a collar approach, in 19 by sternotomy and 4 by thoracotomy. Results were equivalent independent of the approach but only after transsternal incision complications occurred in 3 patients. At 6 months after operation 18 of 35 patients were classified in a lower category following Ossermann's classification, an other 12 were stable and in 5 the information unobtainable...
January 1989: Helvetica Chirurgica Acta
H F Otto
The most important prognostic determinants of the thymomas are the gross findings at operation (equal to the presence or absence of gross invasion of adjacent tissue) and the presence or absence of the thymoma-associated systemic disease, particulary myasthenia gravis. The histologic type of thymoma had no proof value in predicting prognosis with the exception of the so-called atypical thymomas. Thirty-four of 57 patients with thymomas were females and 23 males. The tumors in 40 cases were non-invasive thymomas, and in 17 cases the tumour were invasive of adjacent tissue...
January 26, 1978: Zeitschrift Für Krebsforschung und Klinische Onkologie. Cancer Research and Clinical Oncology
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