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https://www.readbyqxmd.com/read/28073731/discoveries-about-tubercolosis-from-autopsies-topographical-and-morphological-profiles-of-lesions-in-dakar-senegal
#1
I Thiam, C Dial, K Doh, A M Gaye, G Woto-Gaye
Tuberculosis is endemic in Senegal. It is rate of increase and high mortality rate make it a major public health problem. The aim of this study was to describe the topographic, macroscopic, and microscopic aspects of tuberculosis lesions responsible for deaths in Dakar. This is a retrospective study of 158 autopsy reports, collected over 10 years, of deaths due to tuberculosis. The diagnosis of tuberculosis was essentially macroscopic; only equivocal cases had histological analysis. The average age at death was 47 years, and nearly all patients were men (all but 5)...
November 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/27956845/choroidal-tuberculoma-as-a-presenting-sign-of-tuberculosis
#2
Nicolas Arej, Ali Fadlallah, Elias Chelala
Choroidal tuberculoma is a rare ocular form of tuberculosis (TB) that raises both a diagnostic and a therapeutical challenge, especially when occurring without other manifestations of the disease. This study reports the case of a 27-year-old woman who had a unilateral drop of vision (20/100) with ocular pain. Her fundus examination revealed an elevated juxtapapillary choroidal mass measuring 892 µm in diameter, as calculated by optical coherence tomography (OCT), and associated with a serous retinal detachment involving the macula...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27935825/microglia-activation-in-a-pediatric-rabbit-model-of-tuberculous-meningitis
#3
Elizabeth W Tucker, Supriya Pokkali, Zhi Zhang, Vincent P DeMarco, Mariah Klunk, Elizabeth S Smith, Alvaro A Ordonez, Marie-France Penet, Zaver Bhujwalla, Sanjay K Jain, Sujatha Kannan
Central nervous system (CNS) tuberculosis (TB) is the most severe form of extra-pulmonary TB and disproportionately affects young children where the developing brain has a unique host response. New Zealand white rabbits were infected with Mycobacterium tuberculosis via subarachnoid inoculation at postnatal day 4-8 and evaluated until 4-6 weeks post-infection. Control and infected rabbit kits were assessed for the development of neurological deficits, bacterial burden, and postmortem microbiologic and pathologic changes...
December 1, 2016: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/27927706/cerebral-tuberculomas-in-a-patient-with-hairy-cell-leukaemia-treated-with-cladribine
#4
Samuel Barbosa Fonseca, Júlio Rodrigues de Oliveira, Cristina Gonçalves, Virgínia Lopes
A 67-year-old man was treated with cladribine for hairy cell leukaemia. A few weeks later, he presented with persistent headaches, intermittent hypoesthesia of the right upper limb and language impairment. Brain CT scan showed 3 contrast-enhancing lesions. MRI revealed infracentimetric nodular lesions with restricted diffusion. One of the lesions was surgically removed and tested positive for acid-fast bacilli. Moreover, Mycobacterium tuberculosis was confirmed by PCR. Antituberculous drugs were prescribed for 12 months, with complete resolution of neurological deficits...
December 7, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27915334/intraventricular-tuberculoma-in-a-child-a-rare-location
#5
Deepashu Sachdeva, Ishu Bishnoi, Anita Jagetia, Lavlesh Rathore, Atul Agarwal, Vineeta Batra, Amandeep Kaur
Intracranial tuberculoma is an uncommon presentation of tuberculosis, and its occurrence in an intraventricular location is very rare. It is usually confused with glioma, parasitic cyst, and craniopharyngioma. Few case reports exist in the literature on this entity. We report a case of tuberculoma at the foramen of Monro in a 7-year-old child and review the literature in terms of diagnostic dilemma.
December 3, 2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27905289/cerebral-alveolar-echinococcosis-concomitant-with-liver-and-lung-lesions-in-a-young-adult-patient-case-report-and-literature-review
#6
Osman Ersegun Batçık, Ahmet Öğrenci, Orkun Koban, Murat Şakir Ekşi, Turgay Bilge
We present the case of a 25-year-old male harboring multiple brain lesions mimicking tumor metastasis that were revealed to be caused by Echinococcus multilocularis. Cerebral echinococcosis with multiple lesions is rare and might be confused with a brain abscess, tuberculoma, or metastatic tumor disease. Brain magnetic resonance imaging and serological studies are helpful in the differential diagnosis. In case of E. multilocularis, cerebral invasion is the late stage of the disease that necessitates an aggressive treatment protocol...
September 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/27888079/neglected-recurrent-scalp-sinus-calvarial-tuberculosis-with-intracranial-and-extracranial-extension
#7
Krishnamurthy B Holeppagol, Biswaranjan N Nayak, Ram Kumar K Goyal, Arunkumar K Kumar, Prafulla K Sahoo, Debabrat Biswal
BACKGROUND: Calvarial tuberculosis (TB) with intracranial tuberculoma and skin involvement is rare condition even in endemic regions. CASE PRESENTATION: A 43-year-old man presented with a generalized seizure, altered mental state, scalp swelling, and pus-discharging sinus over the scalp. Magnetic resonance imaging of the brain indicated a conflicting diagnosis of anaplastic meningiomas and chronic osteomyelitis with intracranial extension. Débridement and drainage of intracranial pus was performed...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27871010/diagnostic-challenges-in-a-patient-with-myocardial-tuberculoma-a-case-report
#8
Olof Säll, Soon-Ok Cha, Hans Holmberg
INTRODUCTION: Tuberculosis can affect any organ of the body, including the heart. PRESENTATION OF CASE: An 18-year old woman presented with a multifocal tuberculosis infection involving abdominal lymph nodes, a sternotomy wound, an abscess of the abdominal wall and most notably a myocardial tuberculoma. Establishing the diagnosis of the myocardial tuberculoma was challenging mainly due to the location within the heart. Initially a diagnostic percutaneous femoral vascular catheter guided biopsy of the right atrial mass was performed, but later open surgery involving median sternotomy was needed...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27865204/possible-role-of-transforming-growth-factor-%C3%AE-in-tuberculous-meningitis
#9
J Kalita, U K Misra, S K Bhoi, P S Chauhan, Betai Sagar
BACKGROUND: Transforming growth factor β (TGF-β) is an anti-inflammatory cytokine and its role in hydrocephalus and stoke has been suggested. Tuberculous meningitis (TBM) is associated with exudates, stroke, hydrocephalus and tuberculoma, but the role of TGF-β has not been evaluated in relation to these changes. AIM: To evaluate the cerebrospinal fluid (CSF) TGF-β level in the patients with TBM, and correlate these with clinical findings, MRI changes, paradoxical response and outcome at 6months...
November 16, 2016: Cytokine
https://www.readbyqxmd.com/read/27856061/-mesencephalic-lesion-with-ring-enhancement-tuberculoma-or-toxoplasmosis
#10
N Ben Achour, A Nâas, N Hammami, A Rouissi, I Kraoua, H Benrhouma, H Klaa, M Ben Hammouda, I Ben Youssef-Turki
No abstract text is available yet for this article.
January 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27804936/-first-time-revealed-small-formations-of-lungs-under-2-cm-in-diameter-dynamic-follow-up-or-surgery
#11
Yu V Pavlov, V K Rybin
AIM: To develop the treatment algorithm in patients with first time revealed lung lesions smaller than 2 cm. MATERIAL AND METHODS: The study included 110 patients with pathological lung lesions with small dimensions who have been treated in the Burdenko Clinic of Faculty Surgery for the period 1997-2013. All patients underwent surgical removal of lung tissue using different surgical approaches: 44 cases of videothoracoscopic resections, 43 video-assisted minithoracotomies, 23 minithoracotomies...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27798497/recent-advances-in-the-diagnosis-and-management-of-tuberculous-meningitis
#12
Nguyen T H Mai, Guy E Thwaites
PURPOSE OF REVIEW: Tuberculous meningitis is a devastating infection that is hard to diagnose and treat. We have reviewed tuberculous meningitis original research published within the past 18 months, selecting studies which we consider have most advanced knowledge. RECENT FINDINGS: We review advances in diagnostic methods, anti-tuberculosis chemotherapy, and the common complications of tuberculous meningitis. New commercial molecular diagnostic tests, such as GeneXpert MTB/RIF, have an important role in tuberculous meningitis diagnosis, but as with all other available tests, they lack sensitivity and cannot rule out the disease...
February 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27753773/thalidomide-in-refractory-tuberculomas-and-pseudoabscesses
#13
Isabelle Viel-Thériault, Roseline Thibeault, Francois D Boucher, Jean-Philippe Drolet
Paradoxical immune reconstitution inflammatory syndrome is a well-described entity even in immunocompetent children, principally in association with Mycobacterium tuberculosis infections. Central nervous system involvement is a potential life-threatening form, sometimes refractory to standard treatment. We report the case of an HIV-negative refugee teenager, who presented with brain tuberculomas and pseudoabscesses responsive only to thalidomide.
November 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27728514/multiple-cns-tuberculomas-with-brain-abscess-presenting-as-hemiparesis-without-facial-involvement
#14
Harini R, Pradeep Tv, Karibasappa Bg
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27642471/cerebral-tuberculoma-an-entity-not-to-ignore
#15
Samia Frioui, Sonia Jemni
No abstract text is available yet for this article.
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27605978/cerebro-meningeal-infections-in-hiv-infected-patients-a-study-of-116-cases-in-libreville-gabon
#16
Magloire Ondounda, Chinenye Ilozue, Caroline Magne
BACKGROUND: Cerebro-meningeal pathology is common in human immunodeficiency virus (HIV) infection and the aetiology is often difficult to ascertain with certainty. OBJECTIVE: To describe the major suspected and identified causes of meningeal or encephalitic syndromes in HIV infection in Libreville, Gabon. METHODS: A descriptive study using clinical records of patients hospitalised in the Department of Medicine in the Military Hospital of Libreville (Gabon) between January 2006 and May 2010...
June 2016: African Health Sciences
https://www.readbyqxmd.com/read/27600423/-mri-features-of-ventricular-system-tuberculosis
#17
H X Mao, H Y Zhu, Y L Wang, Y Yang, X F You, X W Sun
OBJECTIVE: To study the MRI features of ventricular system tuberculosis. METHODS: Nineteen patients with ventricular system tuberculosis in our hospital from Mar. 2009 to Sep. 2014 were retrospectively identified. Their clinical features and cranial MRI characteristics were reviewed. RESULTS: There were 13 males and 6 females, aged from 15-81 years(mean 37±16). Eight patients had intraventricular tuberculosis, with 5 long striped or irregular shaped intraventricular tuberculosis and 3 with ventricular tuberculoma...
September 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27587940/a-rare-complication-of-tuberculosis-acute-paraplegia
#18
Teoman Aydın, Özgür Taşpınar, Yasar Keskin, Müge Kepekçi, Meryem Güneşer, Adil Çamlı, Hakan Seyithanoğlu, Huriye Kızıltan, Ali Hikmet Eriş
BACKGROUND: Tuberculous radiculomyelitis(TBRM) is one of the complications of neurological tuberculosis and includes cases of arachnoiditis, intradural spinal tuberculoma or granuloma, and spinal cord complications of tuberculous meningitis (TBM). Here, we report a case of TBRM which presented with acute paraplegia. CASE DETAILS: Neurological examination on admission revealed flaccid paralysis, bilateral extensor plantar responses, and exaggerated deep tendon reflexes...
July 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/27586221/choroidal-tuberculoma
#19
Koushik Tripathy, Rohan Chawla
No abstract text is available yet for this article.
March 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/27583096/-myocardial-tuberculoma-unusual-location-of-tuberculosis-a-new-observation-and-review-of-the-literature
#20
Dalal Lambatten, Sanaa Hammi, Yasmina Rhofir, Jamal Eddine Bourkadi
We report the case of a 50-year old patient with a left ventricular tumor whose evolution was marked by impaired general condition and fever. This mass was objectified by echocardiography performed to explore a radiological cardiomegaly. The imaging (MRI) appearance was suggestive of an intra-myocardial tuberculoma Based on our observations, we propose a review of the literature on this unusual location of tuberculosis.
2016: Pan African Medical Journal
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