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https://www.readbyqxmd.com/read/28532916/spinal-intramedullary-tuberculosis-with-concurrent-supra-and-infratentorial-intracranial-disease-in-a-9-month-old-boy-case-report-and-review-of-the-literature
#1
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, C J Kim, Archana Malik
Tuberculous involvement of the spinal cord parenchyma is an exceedingly rare clinical entity; even more so is concurrent intracranial tuberculosis (TB). Spinal intramedullary TB presents with a characteristic subacute myelopathy, with slowly progressive paraplegia, sensory deficits, and/or bowel and bladder dysfunction. Diagnosis is strongly suspected with a clinical history of known TB in conjunction with characteristic findings on magnetic resonance imaging. Management involves multi-agent antitubercular chemotherapy without or with operative intervention...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28488310/use-of-tbag-pha-ratio-in-distinguishing-tuberculoma-from-cancer-in-solitary-pulmonary-nodule-or-mass
#2
Feng Wang, Hongyan Hou, Hongmin Zhou, Shiji Wu, Lie Mao, Min Huang, Botao Yin, Jing Huang, Ziyong Sun
INTRODUCTION: Differentiation of tuberculoma from cancer in solitary pulmonary nodule or mass still remains a major challenge in diagnostic laboratories. OBJECTIVES: The objective of this study is to determine the performance of T-SPOT.TB assay in discriminating these two diseases. METHODS: We prospectively enrolled 331 patients with a solitary pulmonary nodule or mass on CT scans. Conventional tests and T-SPOT.TB assay were simultaneously performed in all participants...
May 9, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28484568/concurrent-multiple-intracranial-and-intramedullary-conus-tuberculoma-a-rare-case-report
#3
Manish Jaiswal, Ashok Gandhi, Devendra Purohit, Radhey Shyam Mittal
Central nervous system (CNS) tuberculosis commonly manifests as tubercular meningitis. CNS tuberculomas are more common intracranially and less frequently involve the spinal cord. Combination of intramedullary with intracranial tuberculomas is extremely rare. We report a case of concurrent occurrence of intramedullary tuberculoma with multiple intracranial tuberculomas in a young 16-year-old boy, who presented with two weeks history of paresthesias and weakness of the lower limbs and diminution of vision in left eye, who had been treated for pulmonary tuberculosis...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28484559/exophytic-pontine-glioblastoma-multiforme-presenting-as-cerebellopontine-angle-mass
#4
Sukhdeep Singh Jhawar, Garewal Singh Sarvpreet, T N Shadangi
Exophytic pontine glioblastoma multiforme (GBM) is a highly malignant tumor of posterior fossa, which is quite rare and such tumor presenting as cerebellopontine (CP) angle mass is even rarer. Here, we describe a 12-year-old boy who presented with imbalance on walking and facial nerve paresis. Magnetic resonance imaging of the brain revealed an irregular ring enhancing mass lesion of the CP angle, which was initially thought to be a tuberculoma, but was later confirmed to be a GBM. Clinical and radiological differentiation of uncommon lesions of CP angle in children is discussed with brief review of pertaining literature...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28471895/unilateral-parkinsonism-symptomatic-of-brain-tuberculoma
#5
Sanjay Pandey, Amit Shankar Singh
We present the case of a patient having left-sided Parkinsonism due to multiple brain tuberculoma on the right side and review the reversible causes of secondary parkinsonism.
May 2017: Neurologist
https://www.readbyqxmd.com/read/28435564/acute-paraplegia-in-a-toddler-a-diagnostic-journey-compounding-the-challenge-in-management-a-case-report
#6
J H Goh, M Fazir, N A Zainal-Abidin, D Amir, M Singh
Spinal tuberculosis is not common in the paediatric age group. Initial clinical features are often vague and non specific until the disease progresses to later stages. We highlight the diagnostic difficulties and management challenges of a complicated extradural tuberculoma with neurological deficits in a very young girl.
July 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28433128/unusual-presentation-of-choroidal-tuberculoma
#7
Mamta Agarwal, Aditya Maitray, Vikas Khetan
No abstract text is available yet for this article.
May 2017: Ophthalmology
https://www.readbyqxmd.com/read/28429346/dynamic-and-contrast-enhanced-ct-imaging-of-lung-carcinoma-pulmonary-tuberculoma-and-inflammatory-pseudotumor
#8
C-R Li, Y-Z Li, Y-M Li, Y-S Zheng
OBJECTIVE: Our main aim was to investigate the effect of dynamic and contrast enhanced CT imaging on differential diagnosis of lung carcinoma, pulmonary tuberculoma, inflammatory pseudotumor, and coexisting pulmonary tuberculosis and lung cancer. PATIENTS AND METHODS: About, 144 patients with pulmonary sarcoidosis as the study subjects were chosen which included: 36 patients with lung carcinoma, 36 patients with pulmonary tuberculoma, 36 patients with inflammatory pseudotumor, 36 patients with coexisting pulmonary tuberculosis and lung cancer...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28416000/brain-tuberculoma-an-unusual-cause-of-stroke-in-a-child-with-trisomy-21-a-case-report
#9
Abdelmoneim E M Kheir, Salah A Ibrahim, Ahlam A Hamed, Badreldin M Yousif, Farouk A Hamid
BACKGROUND: Tuberculosis remains a public health problem in developing countries and is associated with lethal central nervous system complications. Intracranial tuberculomas occur in 13% of children with neurotuberculosis. Patients with trisomy 21 have an increased risk for stroke, which usually stems from cardiovascular defects. CASE PRESENTATION: We report a case of a 12-year-old Sudanese boy with trisomy 21 who was presented to our hospital with focal convulsions and right-sided weakness...
April 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28413535/third-ventricular-tuberculoma-mimicking-as-a-tumor-report-of-a-very-rare-case
#10
Gopal R Sharma, Prashant Kaushal, Bivek Vaidya, Pawan Kumar
Intracranial tuberculoma is a common neurosurgical problem in developing countries; however, intraventricular tuberculoma is a rare entity. Here, we report a rare case of third ventricular tuberculoma in a 21-year-old girl who presented with features of raised intracranial pressure. Radiological findings and management of third ventricular tuberculoma would be discussed and literature regarding such lesions will be reviewed.
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28410693/clinical-and-radiological-spectrum-of-intracranial-tuberculosis-a-hospital-based-study-in-northeast-india
#11
Baiakmenlang Synmon, Marami Das, Ashok K Kayal, Munindra Goswami, Jogesh Sarma, Lakshya Basumatary, Suvorit Bhowmick
Central nervous system tuberculosis (TB) is the most severe extra pulmonary TB having a high mortality and morbidity. OBJECTIVE: To study the various clinical, biochemical, and radiological spectrum of intracranial TB. MATERIALS AND METHOD: Ninety-three patients were enrolled in this prospective study after ethical clearance and consent from August 2013 to May 2015. The entire clinical course with complications and predictors of mortality were assessed. RESULTS: 36 females (38...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28410692/treatment-outcome-of-extrapulmonary-tuberculosis-under-revised-national-tuberculosis-control-programme
#12
J J Cherian, I Lobo, A Sukhlecha, U Chawan, N A Kshirsagar, B L Nair, L Sawardekar
BACKGROUND: Extrapulmonary tuberculosis (EPTB) constitutes 15-20% of tuberculosis cases in India. Earlier studies have evaluated treatment outcomes of EPTB with little information on outcomes of individual site of EPTB. AIMS: The objective was to study the outcome of Directly Observed Treatment Short course (DOTS) treatment of EPTB in different organ systems under Revised National Tuberculosis Control Programme. METHODS: Multi-centric retrospectives record review was carried out in three states in India...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28394836/18f-fdg-pet-ct-of-tuberculosis-meningitis-and-carotid-pseudoaneurysm
#13
Kasturi Rangan, Mudalsha Ravina, Nitin Yadav, Ajay Singh Suraj, Sanjay Gambhir
A 26-year-old woman presented with a headache, left-sided weakness of the body, and pulsatile swelling above the sternal notch. She was treated for abdominal tuberculosis in the past, two years later she developed miliary tuberculosis and was put on modified regimen of antitubercular drugs in view of drug induced hepatitis. Ultrasound neck revealed saccular aneurysm measuring 4 x 3 cm, located in between common carotid arteries with an eccentric thrombus. MRI brain revealed multiple tuberculoma with thick basal meningeal enhancement...
June 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28377860/intra-medullary-tuberculomas-case-series
#14
N Pradeep, Raviraj Ghorpade, Ravishankar Naik, Prakash R Malur
Intramedullary spinal tuberculoma is an extremely rare disease when compared to pulmonary, extrapulmonary and skeletal tuberculosis in developing countries. In the absence of systemic tuberculosis, clinical presentation is non distinctive from other intramedullary lesions. We report two cases of intramedullary tuberculoma both presenting with signs and symptoms of space occupying lesions. Surgical excision was done in both cases following which patients improved neurologically. Histopathological evaluation is essential to provide curative treatment...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28345567/retina-and-the-tubercle-bacillus-four-decades-of-our-journey-and-current-understanding
#15
Pradeep Venkatesh
Tuberculosis continues to be a major pandemic with enormous public health implication. Involvement of ocular tissues in the form of tubercles, tuberculomas, panophthalmitis, and iris granulomas are well recognized as definitive manifestations of tuberculosis. For these lesions, confirmatory evidence is available in the form of demonstration of acid-fast Bacillus on Ziehl-Neelsen staining. For other retinochoroidal disorders such as central serous chorioretinopathy, retinal vasculitis, and presumed ocular tuberculosis, hard evidence about the role of Mycobacterium tuberculosis is lacking...
February 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28302234/tuberculous-dactylitis-with-concomitant-thyroid-involvement-a-rare-presentation-of-childhood-tuberculosis
#16
Sobia Qamar, Farrah Naz, Samia Naz, Iftikhar Ejaz
Extrapulmonary tuberculosis rarely presents as thyroid involvement along with other manifestations, and poses a diagnostic challenge on account of paucibacillary nature of disease. In general, the diagnosis of tuberculosis is based on epidemiological risk factors, clinical features, imaging studies, in addition to a positive skin testing or Interferon Gamma Release Assay (IGRA). A 14-year boy presented with history of fever and weight loss for one year. On examination, he had painful swelling of fingers and toes along with a painless thyroid nodule and squint...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28281443/central-nervous-system-tuberculosis
#17
John M Leonard
Central nervous system tuberculosis (CNS-TB) takes three clinical forms: meningitis (TBM), intracranial tuberculoma, and spinal arachnoiditis. TBM predominates in the western world and presents as a subacute to chronic meningitis syndrome with a prodrome of malaise, fever, and headache progressing to altered mentation and focal neurologic signs, followed by stupor, coma, and death within five to eight weeks of onset. The CSF formula typically shows a lymphocytic pleocytosis, and low glucose and high protein concentrations...
March 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28253602/-a-clinical-report-of-five-cases-of-central-nervous-system-miliary-tuberculomas-first-diagnosed-by-neurologists
#18
X Huang, X Y Wang, Z H Zhu, X K Qi, Y X Yu
To explore the clinical characteristics and imaging features of miliary tuberculomas in central nervous system(CNS). A total of 5 cases diagnosed with tuberculosis in CNS first diagnosed by neurologists in Navy General Hospital of PLA were enrolled in the study. All clinical and imaging data were collected and analyzed retrospectively. The main initial symptoms were fever and headache (4/5). Multiple diffused miliary lesions were shown by brain MRI, with maximum diameter ranged from 1-4 mm and ring-shape or nodular enhancement after gadolinium injection...
March 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28183710/pituitary-tuberculoma-with-subsequent-drug-resistant-tuberculous-lymphadenopathy-an-uncommon-presentation-of-a-common-disease
#19
Geethu Antony, Riddhi Dasgupta, Geetha Chacko, Nihal Thomas
We report a case of pituitary tuberculosis which presented as a non-functioning pituitary macroadenoma, and subsequently developed multidrug-resistant tuberculous lymphadenopathy. Pituitary tuberculosis continues to be a rare presentation of tuberculosis, but incidence and prevalence are expected to grow with increasing numbers of multidrug-resistant tuberculosis. Isolated pituitary tuberculosis is rare. Tuberculosis should be considered in the differential diagnosis in evaluation of a sellar mass.
February 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28166919/a-lengthy-primary-intramedullary-tuberculoma-of-the-spinal-cord-extending-from-c4-to-d8-a-case-report
#20
V Chandramouleeswaran, Hazeena P Philo, D Balasubramaniam, Rajeswari Ramachandran
Spinal intramedullary tuberculoma is a rare cause of spinal cord compression. We report a case that had an intramedullary spinal cord tuberculomas where the diagnosis was made by MRI and biopsy. The clinical presentation was that of a cord compression in a 30-year-old male febrile patient. This case of intramedullary spinal tuberculoma with a longitudinally extending lesion of the cervicothoracic spine from C4 to D8 is presented for the rarity of its presentation.
January 2017: Indian Journal of Tuberculosis
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