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https://www.readbyqxmd.com/read/28941861/concurrent-intramedullary-spinal-cord-and-multiple-intracranial-tuberculomas-with-tuberculous-optic-neuritis-a-rare-case-report
#1
Lulup Sahoo, Ashok Kumar Mallick, Geeta Mohanty, Kali Prasanna Swain, Soumyadarshan Nayak, Ashwini Kumar Sahu
Tuberculosis (TB) remains a worldwide burden, with a large majority of new active TB cases occurring in underdeveloped and developing countries. Tuberculous meningitis (TBM) is one of the common infections of central nervous system. Other manifestations include intracranial tuberculoma, tubercular brain abscess, spinal tuberculoma, and granulomatous arachnoiditis. Visual impairment in TBM may be due to optic neuritis, optochiasmatic arachnoiditis (OCA), tuberculoma in the chiasmatic region or in the optic pathways, chorioretinitis, secondary to hydrocephalus and increased intracranial pressure, and finally due to ethambutol toxicity...
October 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28936096/advanced-elbow-joint-tuberculosis-with-cervicothoracic-junction-extramedullary-tuberculoma-in-a-school-boy-unusual-association
#2
Guru Dutta Satyarthee
No abstract text is available yet for this article.
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28927854/tuberculoma-cavitation-a-rare-aspect-of-a-common-disease-clinical-image
#3
Rosana Souza Rodrigues, Miriam Menna Barreto, Edson Marchiori
No abstract text is available yet for this article.
September 15, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28904582/giant-intracerebral-tuberculoma-with-complete-disappearance-on-antitubercular-therapy-alone-in-a-pediatric-case-a-case-illustration-with-review-of-management-strategy
#4
Guru Dutta Satyarthee
The Central nervous system can be affected in extrapulmonary tuberculosis. The intracranial tuberculoma occurrence is a rare entity occurrence; most often occur in the form of discrete small multiple lesions. Rarely a large sized tuberculoma is observed with mass effects and usually managed surgically to provide rapid relief of mass effect, histopathological confirmation of diagnosis, reduction of pathological mass thereby increasing efficacy of medical therapy. Author reports an extremely rare case of giant tuberculoma occurring in a pediatric patient, which was managed with antituberculous medication along with cerebral decongestant...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28852602/the-importance-of-a-complete-differential-case-report-of-a-tuberculoma-in-a-patient-without-pulmonary-involvement
#5
Pooja Sethi, Jennifer Treece, Chidinma Onweni, Vandana Pai, Zia Rahman, Siddharth Singh
Patients with a tuberculoma typically present with pulmonary involvement of tuberculosis and have risk factors for tuberculosis (TB). The risk factors for tuberculosis include bacillary load, proximity to infectious case, immunosuppressive conditions, malnutrition, young age, diabetes mellitus, working in healthcare, recent incarceration, alcohol use, and tobacco use. Although rare, it is possible for a patient to present with a tuberculoma despite the absence of risk factors for tuberculosis other than diabetes and without pulmonary involvement...
June 28, 2017: Curēus
https://www.readbyqxmd.com/read/28806025/brain-tuberculoma-a-case-report-and-literature-review
#6
Khalil Aloreidi, Jamal Dodin, Jeremy Berg, Wendell Hoffman
We are reporting on a rare case of central nervous system tuberculosis (TB) in the state of South Dakota. Our case features one of the most infrequent forms of TB in the brain: multiple tuberculomas. A 44-year-old immunocompetent man was admitted complaining of a headache and fever for a week. His physical exam was unremarkable. A magnetic resonance imaging scan of his brain showed two ring-enhancing lesions. The largest lesion was excised surgically and the histopathology exam was consistent with tuberculoma...
July 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28791993/-morphological-signs-of-inflammatory-activity-in-different-clinical-forms-of-drug-resistant-pulmonary-tuberculosis
#7
A A Elipashev, V O Nikolsky, A S Shprykov
AIM: to determine whether the activity of tuberculous inflammation is associated with different clinical forms of drug-resistant pulmonary tuberculosis. SUBJECTS AND METHODS: The material taken from 310 patients operated on in 2010-2015 were retrospectively examined. The patients underwent economical lung resections of limited extent (typical and atypical ones of up to 3 segments) for circumscribed forms of tuberculosis with bacterial excretion. A study group consisted of 161 (51...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28761548/intracranial-en-plaque-tuberculoma-impersonating-en-plaque-meningioma-case-report-and-brief-review-of-literature
#8
Jayendra Kumar, Jeevesh Mallik, Ben A Strickland, Viraat Harsh, Anil Kumar
BACKGROUND: Tuberculosis of the central nervous system continues to be a major health hazard in developing countries like India. There are various manifestations of central nervous system tuberculosis including meningitis and space occupying lesions. We present a case of tuberculoma en-plaque which is often initially confused with a meningioma on presentation. We also review the literature relevant to this unusual entity. METHODS: A search of PubMed, PubMed Central, the Cochrane Library, and MEDLINE were performed to identify all English language reports of intracranial en-plaque tuberculomas...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28733940/pituitary-tuberculoma-a-rare-cause-of-sellar-mass
#9
REVIEW
H M Zia-Ul-Hussnain, M Farrell, S Looby, W Tormey, M Javadpour, S Mcconkey, C J Thompson
INTRODUCTION: Pituitary tuberculosis is an uncommon cause of sellar mass [1]; the estimated prevalence worldwide is not known, and there have been no reports of the condition occurring in Ireland. Tuberculosis of the pituitary gland may present as a sellar mass or with symptoms of hypopituitarism. CASE PRESENTATION: A 41-year-old woman, with a short prodromal history without endocrine symptoms, was found to have pituitary tuberculosis after the demonstration of a sellar mass on MRI, and lumbar puncture findings consistent with lymphocytic meningitis...
July 21, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28718234/paediatrics-brain-imaging-in-epilepsy-common-presenting-symptoms-and-spectrum-of-abnormalities-detected-on-mri
#10
Azmat Ali, Faiza Akram, Ghayyur Khan, Shaukat Hussain
BACKGROUND: Epilepsy, a common neurological disorder can present at any age and has a number of aetiologies with underlying brain disease being the most common aetiology. Brain imaging becomes important and mandatory in the work up for epilepsy in localization and lateralization of the seizure focus. METHODS: This cross-sectional study was conducted in the department of Radiology Ayub Medical Teaching Institution Abbottabad from 1st March 2015 to 31st March 2016...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28714494/computerized-axial-tomography-findings-in-children-with-afebrile-seizures-a-hospital-based-study-at-eastern-nepal
#11
P Poudel, M K Gupta, S P Kafle
BACKGROUND: Computerized Tomography can be performed in resource limited areas where Magnetic Resonance Imaging is less practical. This study was conducted to find out the proportion of cases with abnormal CT scan and findings of CT scan in children with afebrile seizures in a resource limited area. METHODS: This prospective study was conducted from 1st July 2009 to 31st March 2014 in a university hospital of Nepal. Patients (1 month to 20 years of age) presenting with history of afebrile seizure were included...
January 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28694861/an-uncommon-cause-of-longitudinally-extensive-transverse-myelitis
#12
Catalina Coclitu, Athena Mergeani, Teodora Parvu, Octaviana Rusu, Andrei Ciobotaru, Ovidiu Bajenaru, Florina Antochi
Considering that currently Romania has the highest tuberculosis incidence in Europe, the recognition of the infection is an acknowledged health issue. Central nervous system tuberculosis accounts for approximately 1% of all cases of tuberculosis. Longitudinally extensive transverse myelitis is a contiguous infl ammatory lesion of the spinal cord which involves three or more spinal segments. In tuberculosis, spinal cord involvement is rare and is usually rather due to radiculomyelitis or spinal tuberculoma, and only very rare due to longitudinally extensive transverse myelitis...
September 2016: Mædica
https://www.readbyqxmd.com/read/28678217/choroid-plexus-tuberculoma-diagnosis-management-and-role-of-endoscopy
#13
Nishanth Sadashiva, Bevinahalli N Nandeesh, Dhaval Shukla, Bhagavatula I Devi
Ventricular involvement in central nervous system tuberculosis can be in the form of tuberculous ependymitis, intraventricular tuberculoma, intraventricular tuberculous abscess, choroid plexitis and choroid plexus tuberculoma. Only a few cases of choroid plexus tuberculomas have been described and even more rare is the description of the role of endoscopy in management of intraventricular tuberculomas. We report a 33-year-old patient while on treatment for tubercular meningitis who developed a left side choroid plexus lesion with loculated temporal horn...
July 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/28673337/rare-presentation-of-intractable-tuberculous-panophthalmitis-with-intraocular-and-intraorbital-abscesses-a-case-report
#14
Sutasinee Boonsopon, Nattaporn Tesavibul, Mongkol Uiprasertkul, Supinda Leeamornsiri, Pitipol Choopong
BACKGROUND: We report a rare presentation of extrapulmonary tuberculosis. CASE PRESENTATION: A 29-year-old Burmese woman with human immunodeficiency virus infection and known pulmonary tuberculosis who had been treated for 5 months presented to our hospital with unilateral progressive painful visual loss of 1 month's duration. She was diagnosed with tuberculous panophthalmitis with subretinal and intraorbital abscesses, conjunctival abscess, and extraocular muscle tuberculoma...
July 4, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28659187/tuberculous-meningoencephalitis-associated-with-brain-tuberculomas-during-pregnancy-a-case-report
#15
Sadie Namani, Shemsedin Dreshaj, Arieta Zogaj Berisha
BACKGROUND: Tuberculous meningitis is globally highly prevalent and is commoner in resource-limited countries and in patients with immunosuppression. Central nervous system tuberculosis is one of the severest forms of extrapulmonary tuberculosis during pregnancy and associated brain tuberculomas have been rarely reported. With the availability of neuroimaging at our hospital center, we present the first case of tuberculous meningoencephalitis associated with brain tuberculomas during pregnancy...
June 29, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28605426/biomarkers-of-cerebral-injury-and-inflammation-in-pediatric-tuberculous-meningitis
#16
Ursula K Rohlwink, Katya Mauff, Katalin A Wilkinson, Nico Enslin, Emmanuel Wegoye, Robert J Wilkinson, Anthony A Figaji
Background: Tuberculous meningitis (TBM) leads to death or disability in half the affected individuals. Tools to assess severity and predict outcome are lacking. Neuro-specific biomarkers could serve as markers of the severity and evolution of brain injury, but have not been widely explored in TBM. We examined biomarkers of neurological injury (neuromarkers) and inflammation in pediatric TBM and their association with outcome. Methods: Blood and cerebrospinal fluid (CSF) of children with TBM and hydrocephalus taken on admission and over 3 weeks were analysed for neuromarkers S100B, neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP), and multiple inflammatory markers...
June 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28588774/solitary-pulmonary-caseating-granulomas-a-5-year-retrospective-single-center-analysis
#17
Hidehiro Watanabe, Tomonori Uruma, Ikuo Seita, Tsuyoshi Oishi, Yusuke Watanabe, Ayaka Tsukimori, Yoshiteru Haga, Shinji Fukushima, Akihiro Sato, Itaru Nakamura, Tetsuya Matsumoto
Solitary pulmonary caseating granulomas (SPCGs) are a characteristic type of tuberculomas associated with infection with non-tuberculous mycobacteria (NTM) and other microbes; however, their significance remains unclear. The aim of the present study was to describe the clinical characteristics of patients with SPCGs in terms of diagnosis, presence of lung cancer and treatment status. A retrospective analysis of 17 immunocompetent patients with histopathologically confirmed caseating granulomas after undergoing video-assisted thoracoscopic surgery (VATS) was conducted at our center between 2011 and 2015...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28532916/spinal-intramedullary-tuberculosis-with-concurrent-supra-and-infratentorial-intracranial-disease-in-a-9-month-old-boy-case-report-and-review-of-the-literature
#18
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, C J Kim, Archana Malik
Tuberculous involvement of the spinal cord parenchyma is an exceedingly rare clinical entity; even more so is concurrent intracranial tuberculosis (TB). Spinal intramedullary TB presents with a characteristic subacute myelopathy, with slowly progressive paraplegia, sensory deficits, and/or bowel and bladder dysfunction. Diagnosis is strongly suspected with a clinical history of known TB in conjunction with characteristic findings on magnetic resonance imaging. Management involves multi-agent antitubercular chemotherapy without or with operative intervention...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28488310/use-of-tbag-pha-ratio-in-distinguishing-tuberculoma-from-cancer-in-solitary-pulmonary-nodule-or-mass
#19
Feng Wang, Hongyan Hou, Hongmin Zhou, Shiji Wu, Lie Mao, Min Huang, Botao Yin, Jing Huang, Ziyong Sun
INTRODUCTION: Differentiation of tuberculoma from cancer in solitary pulmonary nodule or mass still remains a major challenge in diagnostic laboratories. OBJECTIVES: The objective of this study is to determine the performance of T-SPOT.TB assay in discriminating these two diseases. METHODS: We prospectively enrolled 331 patients with a solitary pulmonary nodule or mass on CT scans. Conventional tests and T-SPOT.TB assay were simultaneously performed in all participants...
May 9, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28484568/concurrent-multiple-intracranial-and-intramedullary-conus-tuberculoma-a-rare-case-report
#20
Manish Jaiswal, Ashok Gandhi, Devendra Purohit, Radhey Shyam Mittal
Central nervous system (CNS) tuberculosis commonly manifests as tubercular meningitis. CNS tuberculomas are more common intracranially and less frequently involve the spinal cord. Combination of intramedullary with intracranial tuberculomas is extremely rare. We report a case of concurrent occurrence of intramedullary tuberculoma with multiple intracranial tuberculomas in a young 16-year-old boy, who presented with two weeks history of paresthesias and weakness of the lower limbs and diminution of vision in left eye, who had been treated for pulmonary tuberculosis...
April 2017: Asian Journal of Neurosurgery
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