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Isabelle Viel-Thériault, Roseline Thibeault, Francois D Boucher, Jean-Philippe Drolet
Paradoxical immune reconstitution inflammatory syndrome is a well-described entity even in immunocompetent children, principally in association with Mycobacterium tuberculosis infections. Central nervous system involvement is a potential life-threatening form, sometimes refractory to standard treatment. We report the case of an HIV-negative refugee teenager, who presented with brain tuberculomas and pseudoabscesses responsive only to thalidomide.
November 2016: Pediatric Infectious Disease Journal
Harini R, Pradeep Tv, Karibasappa Bg
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Samia Frioui, Sonia Jemni
No abstract text is available yet for this article.
2016: Pan African Medical Journal
Magloire Ondounda, Chinenye Ilozue, Caroline Magne
BACKGROUND: Cerebro-meningeal pathology is common in human immunodeficiency virus (HIV) infection and the aetiology is often difficult to ascertain with certainty. OBJECTIVE: To describe the major suspected and identified causes of meningeal or encephalitic syndromes in HIV infection in Libreville, Gabon. METHODS: A descriptive study using clinical records of patients hospitalised in the Department of Medicine in the Military Hospital of Libreville (Gabon) between January 2006 and May 2010...
June 2016: African Health Sciences
H X Mao, H Y Zhu, Y L Wang, Y Yang, X F You, X W Sun
OBJECTIVE: To study the MRI features of ventricular system tuberculosis. METHODS: Nineteen patients with ventricular system tuberculosis in our hospital from Mar. 2009 to Sep. 2014 were retrospectively identified. Their clinical features and cranial MRI characteristics were reviewed. RESULTS: There were 13 males and 6 females, aged from 15-81 years(mean 37±16). Eight patients had intraventricular tuberculosis, with 5 long striped or irregular shaped intraventricular tuberculosis and 3 with ventricular tuberculoma...
September 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
Teoman Aydın, Özgür Taşpınar, Yasar Keskin, Müge Kepekçi, Meryem Güneşer, Adil Çamlı, Hakan Seyithanoğlu, Huriye Kızıltan, Ali Hikmet Eriş
BACKGROUND: Tuberculous radiculomyelitis(TBRM) is one of the complications of neurological tuberculosis and includes cases of arachnoiditis, intradural spinal tuberculoma or granuloma, and spinal cord complications of tuberculous meningitis (TBM). Here, we report a case of TBRM which presented with acute paraplegia. CASE DETAILS: Neurological examination on admission revealed flaccid paralysis, bilateral extensor plantar responses, and exaggerated deep tendon reflexes...
July 2016: Ethiopian Journal of Health Sciences
Koushik Tripathy, Rohan Chawla
No abstract text is available yet for this article.
March 2016: National Medical Journal of India
Dalal Lambatten, Sanaa Hammi, Yasmina Rhofir, Jamal Eddine Bourkadi
We report the case of a 50-year old patient with a left ventricular tumor whose evolution was marked by impaired general condition and fever. This mass was objectified by echocardiography performed to explore a radiological cardiomegaly. The imaging (MRI) appearance was suggestive of an intra-myocardial tuberculoma Based on our observations, we propose a review of the literature on this unusual location of tuberculosis.
2016: Pan African Medical Journal
Tuğba Kemaloğlu Öz, Mahmoud Elsayed, Navin C Nanda, Koray Kalenderoğlu, Şükrü Akyüz, Işıl Atasoy, Altuğ Ösken, Tolga Onuk, Mehmet Eren
Intracardiac tuberculomas are extremely rare, and cardiac involvement in tuberculosis accounts for only 0.5% of extrapulmonary tuberculosis. We report for the first time incremental value of live/real time three-dimensional transesophageal echocardiography over two-dimensional transesophageal echocardiography in the assessment of a tuberculoma involving the left atrium and left atrial appendage.
September 2016: Echocardiography
Koushik Tripathy, Rohan Chawla, Yog Raj Sharma
The authors present a 36-year-old female with pulmonary tuberculosis who developed a choroidal tuberculoma in the left eye. The choroidal tuberculoma successfully resolved with visual gain following oral anti-tubercular and oral steroid therapy leaving behind a chorioretinal scar. One year after the completion of anti-tubercular treatment, she developed visual loss due to the development of a secondary choroidal neovascular membrane at the fovea. This was treated successfully with one intravitreal injection of bevacizumab in the left eye...
August 19, 2016: Ocular Immunology and Inflammation
Sasima Srisukh, Tananun Tanpaibule, Sasisopin Kiertiburanakul, Atthaporn Boongird, Duangkamon Wattanatranon, Theerapol Panyaping, Chutintorn Sriphrapradang
Pituitary tuberculoma is extremely rare, even in endemic regions of tuberculosis and much less frequently as a presentation of pituitary apoplexy. We describe a 25-year-old female presented with sudden onset of headache and vision loss of left eye which mimicking symptoms of pituitary apoplexy. MRI of the pituitary gland showed a rim-enhancing lesion at the intrasellar region extending into the suprasellar area, but absence of posterior bright spot with enhancement of the pituitary stalk. Pituitary hormonal evaluation revealed panhypopituitarism and diabetes insipidus...
2016: IDCases
Takashi Fujii, Naoki Otani, Yohei Otsuka, Takashi Matsumoto, Shunsuke Tanoue, Hideaki Ueno, Satoshi Tomura, Arata Tomiyama, Terushige Toyooka, Kojiro Wada, Kentaro Mori
We herein report a surgical case of multiple cerebral calculi located within the chiasmatic cistern resulting in visual disturbance. A 61-year-old man experienced homonymous lower right quadrantanopsia a few years prior. Non-enhanced head CT revealed multiple calcified lesions of about 7-mm within the basal cistern. MRI showed the lesion compressing the left optic tract. We could not remove the entire lesion because of severe adhesion to the optic tract. A pathological test showed calcified lesions with lymphocyte infiltration...
August 2016: No Shinkei Geka. Neurological Surgery
Sendhil Coumary Arumugam, Sharmila Murugesan, Sunitha Pradeep, Lopamudra John, Vasavi Kolluru
Occurrence of eclampsia before 20 weeks of pregnancy and after 48 hours of delivery in the absence of typical signs of hypertension and or proteinuria is termed as atypical eclampsia. Atypical or non-classic eclampsia will have some symptoms of eclampsia but without the usual proteinuria or hypertension. All patients with atypical onset should undergo neurological evaluation to rule out neurologic causes of seizures. Cerebral tuberculosis is a rare and serious form of disease secondary to haematogenous spread of Mycobacterium tuberculosis...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Praveen Kumar Srikanteswara, Praveen Kumar Pampapati, Kalpana Ramesh Yelsangikar
INTRODUCTION: Case reports pertaining to Magnetic Resonance Imaging (MRI) diagnosis of en-plaque tuberculoma are limited. To the best of our knowledge, descriptions about en-plaque tuberculoma are limited to few isolated case reports. This paper comprehensively depicts the clinical and radiological features in such patients and may serve not to miss this uncommon manifestation of a common central nervous system infection. MATERIALS AND METHODS: A descriptive documentation of the patient cohort with a detailed history and neurological examination were carried out in all the patients...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Dragan Subotic, Piotr Yablonskiy, Giorgia Sulis, Ioan Cordos, Danail Petrov, Rosella Centis, Lia D'Ambrosio, Giovanni Sotgiu, Giovanni Battista Migliori
Tuberculosis (TB) is still a major public health concern, mostly affecting resource-constrained settings and marginalized populations. The fight against the disease is hindered by the growing emergence of drug-resistant forms whose management can be rather challenging. Surgery may play an important role to support diagnosis and treatment of the most complex cases and improve their therapeutic outcome. We conducted a non-systematic review of the literature based on relevant keywords through PubMed database. Papers in English and Russian were included...
July 2016: Journal of Thoracic Disease
Prashant S Adole, Parampreet S Kharbanda, Sadhna Sharma
BACKGROUND & OBJECTIVES: Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication. N-acetyltransferase 2 (NAT2) enzyme catalyses two acetylation reactions in INH metabolism and NAT2 gene polymorphism leads to slow and rapid acetylators. The present study was aimed to evaluate the effect of allelic variants of N-acetyltransferase 2 (NAT2) gene as a predisposing factor for phenytoin toxicity in patients with TBM or tuberculoma having seizures, and taking INH and phenytoin simultaneously...
May 2016: Indian Journal of Medical Research
Mingzhi Song, Xiaohong Sun, Ran Sun, Tao Liu, Gang Li, Song Liu, Ming Lu, Wei Qu
Ulnar nerve tuberculoma is a rare case of tuberculous involvement of the peripheral nerve, which has attracted the attention of physicians. Here, we report the case of a patient with ulnar nerve tuberculoma. A 25-year-old patient presented progressive numbness on his left hand and forearm, and typical symptoms were not evident. The patient had no history of trauma or contact with any individuals with active tuberculosis. Exploratory surgery was performed and a granuloma-like lesion was found on the left ulnar nerve of the patient...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Eliza Manea, Daniela Munteanu, Raluca Jipa, Ruxandra Moroti, Victoria Arama, Ioan-Alexandru Diaconu, Adriana Hristea
BACKGROUND: Immune reconstitution inflammatory syndrome (IRIS) related to tuberculosis (TB) is an exacerbation of an inflammatory response that most often occurs in HIV-infected patients but it has also been observed in non-HIV immunocompromised hosts. We describe two cases of TB associated IRIS with CNS involvement, one in a patient diagnosed with HIV infection and the other in a patient with immunosuppression due to anti tumor necrosis factor treatment. CASE REPORT; The first case was a 40-year-old man, newly diagnosed with HIV infection, who developed right hemiplegia and expressive aphasia...
October 2015: Pneumologia: Revista Societății Române de Pneumologie
Shujun Geng, Lijuan Li, Jianling Liu, Tao Song
The aim of the study was to compare the mid- and long-term effects of different treatments such as CT-guided percutaneous pulmonary paracentesis, tuberculoma perfusing chemotherapy and whole-body standard chemotherapy or extended chemotherapy on safety and effectiveness for pleural chemotherapy. A total of 60 subjects diagnosed to have pleural tuberculosis between February 2010 and February 2014 were prospectively selected for this study and were considered as the experimental group. Seventy pleural tuberculosis patients who underwent treatment between February 2006 and February 2010 were considered as the control group...
August 2016: Experimental and Therapeutic Medicine
Parth Rali, Hammad Arshad, Eric Bihler
We present a case of tuberculous (TB) meningitis in nonimmunocompromised immigrant worker who initially presented with headache and later with generalized tonic clonic seizures and disseminated tuberculosis.
2016: Case Reports in Pulmonology
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