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https://www.readbyqxmd.com/read/28340321/exploring-the-relationship-between-cognition-and-functional-verbal-reasoning-in-adults-with-severe-traumatic-brain-injury-at-six-months-post-injury
#1
Petra Avramović, Belinda Kenny, Emma Power, Skye McDonald, Robyn Tate, Louise Hunt, Sheila MacDonald, Rob Heard, Leanne Togher
OBJECTIVE(S): This study aims to determine the association between cognitive impairment and functional verbal reasoning in adults with severe traumatic brain injury (TBI), at six months post-injury. METHOD(S): 38 participants with severe TBI were assessed using the four tasks on the Functional Assessment of Verbal Reasoning and Executive Strategies (FAVRES) [1] and a battery of neuropsychological tests at 6 months post injury in a cross-sectional observational study...
March 24, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28340237/pain-and-cognition-in-multiple-sclerosis
#2
R Scherder, N Kant, E Wolf, A C M Pijnenburg, E Scherder
Objective. : The goal of the present study was to examine the relationship between pain and cognition in patients with multiple sclerosis. Design. : Cross-sectional. Setting. : Nursing home and personal environment of the investigators. Subjects. : Two groups of participants were included: 91 patients with multiple sclerosis and 80 matched control participants. Methods. : The level of pain was measured by the following pain scales: Number of Words Chosen-Affective, Colored Analogue Scale for pain intensity and suffering from pain, and the Faces Pain Scale...
March 15, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28339998/executive-functioning-in-pediatric-chronic-pain-do-deficits-exist
#3
Karen E Weiss, Cynthia Harbeck-Weber, Michael J Zaccariello, Jacqueline N Kimondo, Tracy E Harrison, Barbara K Bruce
Objective. : Despite ample research documenting deficits in executive functioning for adults with chronic pain, the literature on pediatric patients with chronic pain is limited and provides mixed results. The current study sought to further investigate the nature of executive dysfunction in this population and also examine the relationships between pain intensity, duration, and catastrophizing with sustained attention, working memory, and self- and parent-report of executive functioning...
March 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28338440/a-study-of-cognitive-function-in-treatment-refractory-obsessive-compulsive-disorder-treated-with-capsulotomy
#4
Feilong Gong, Peng Li, Bin Li, Shizhen Zhang, Xinjie Zhang, Sen Yang, Hongbin Liu, Wei Wang
OBJECTIVE Anterior capsulotomy (AC) is sometimes used as a last resort for treatment-refractory obsessive-compulsive disorder (OCD). Previous studies assessing neuropsychological outcomes in patients with OCD have identified several forms of cognitive dysfunction that are associated with the disease, but few have focused on changes in cognitive function in OCD patients who have undergone surgery. In the present study, the authors investigated the effects of AC on the cognitive function of patients with treatment-refractory OCD...
March 24, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28337476/cerebrospinal-fluid-biomarker-examination-as-a-tool-to-discriminate-behavioral-variant-frontotemporal-dementia-from-primary-psychiatric%C3%A2-disorders
#5
Everard G B Vijverberg, Annemiek Dols, Welmoed A Krudop, Marta Del Campo Milan, Cora J Kerssens, Flora Gossink, Niels D Prins, Max L Stek, Philip Scheltens, Charlotte E Teunissen, Yolande A L Pijnenburg
INTRODUCTION: To prospectively determine the diagnostic value of cerebrospinal fluid (CSF) levels total-tau (tau) to amyloid-β1-42 ratio (Aβ1-42) ratio (tau/Aβ1-42 ratio), phosphorylated-tau (p-tau) to tau ratio (p-tau/tau ratio), neurofilament light chain (NfL) and YKL40 in the late-onset frontal lobe syndrome, in particular for the differential diagnosis of behavioral variant frontotemporal dementia (bvFTD) versus primary psychiatric disorders (PSY). METHOD: We included patients with a multidisciplinary 2-year-follow-up diagnosis of probable/definite bvFTD (n = 22) or PSY (n = 25), who underwent a detailed neuropsychiatric clinical examination, neuropsychological test battery, and magnetic resonance imaging at baseline...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28335872/cognitive-impairment-in-euthymic-pediatric-bipolar-disorder-a-systematic-review-and-meta-analysis
#6
REVIEW
Liana R Elias, Kamilla W Miskowiak, Antônio M O Vale, Cristiano A Köhler, Hanne L Kjærstad, Brendon Stubbs, Lars V Kessing, Eduard Vieta, Michael Maes, Benjamin I Goldstein, André F Carvalho
OBJECTIVE: To perform a systematic review and meta-analysis of studies investigating neurocognition in euthymic youths with bipolar disorder (BD) compared to healthy controls (HCs). METHOD: A systematic literature search was conducted in the PubMed/MEDLINE, PsycINFO, and EMBASE databases from inception up until March 23, 2016, for original peer-reviewed articles that investigated neurocognition in euthymic youths with BD compared to HCs. Effect sizes (ES) for individual tests were extracted...
April 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28335460/neuropsychology-of-aesthetic-judgment-of-ambiguous-and-non-ambiguous-artworks
#7
Maddalena Boccia, Sonia Barbetti, Laura Piccardi, Cecilia Guariglia, Anna Maria Giannini
Several affective and cognitive processes have been found to be pivotal in affecting aesthetic experience of artworks and both neuropsychological as well as psychiatric symptoms have been found to affect artistic production. However, there is a paucity of studies directly investigating effects of brain lesions on aesthetic judgment. Here, we assessed the effects of unilateral brain damage on aesthetic judgment of artworks showing part/whole ambiguity. We asked 19 unilaterally brain-damaged patients (10 left and 9 right brain damaged patients, respectively LBDP and RBDP) and 20 age- and education-matched healthy individuals (controls, C) to rate 10 Arcimboldo's ambiguous portraits (AP), 10 realistic Renaissance portraits (RP), 10 still life paintings (SL), and 10 Arcimboldo's modified portraits where only objects/parts are detectable (AO)...
March 18, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28334644/low-level-inorganic-arsenic-exposure-and-neuropsychological-functioning-in-american-indian-elders
#8
Clint R Carroll, Carolyn Noonan, Eva M Garroutte, Ana Navas-Acien, Steven P Verney, Dedra Buchwald
BACKGROUND: Inorganic arsenic at high and prolonged doses is highly neurotoxic. Few studies have evaluated whether long-term, low-level arsenic exposure is associated with neuropsychological functioning in adults. OBJECTIVES: To investigate the association between long-term, low-level inorganic arsenic exposure and neuropsychological functioning among American Indians aged 64-95. METHODS: We assessed 928 participants in the Strong Heart Study by using data on arsenic species in urine samples collected at baseline (1989-1991) and results of standardized tests of global cognition, executive functioning, verbal learning and memory, fine motor functioning, and speed of mental processing administered during comprehensive follow-up evaluations in 2009-2013...
March 18, 2017: Environmental Research
https://www.readbyqxmd.com/read/28334403/cognitive-estimation-in-non-demented-parkinson-s-disease
#9
Federica Scarpina, Alessandro Mauro, Guido E D'Aniello, Giovani Albani, Gianluca Castelnuovo, Erika Ambiel, Sarah E MacPherson
Objective: The Cognitive Estimation Test (CET) is widely used in clinical and research settings to assess the ability to produce reasonable estimates to items that individuals would not know that the exact answer (e.g., "How fast do race horses run?"). We examined the performance of non-demented Parkinson's disease (PD) patients on the CET, because previous studies reported heterogeneous results about possible cognitive estimation impairments in PD. We also examined whether PD patients improve their performance if given the chance to reconsider their initial CET responses...
March 10, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28334378/patterns-of-false-memory-in-patients-with-huntington-s-disease
#10
I-Wen Chen, Chiung-Mei Chen, Yih-Ru Wu, Mau-Sun Hua
Objective: Increased false memory recognition in patients with Huntington's disease (HD) has been widely reported; however, the underlying memory constructive processes remain unclear. The present study explored gist memory, item-specific memory, and monitoring ability in patients with HD. Method: Twenty-five patients (including 13 patients with mild HD and 12 patients with moderate-to-severe HD) and 30 healthy comparison participants (HC) were recruited. We used the Deese-Roediger-McDermott (DRM) paradigm to investigate participants' false recognition patterns, along with neuropsychological tests to assess general cognitive function...
March 17, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28334244/cognitive-screening-tests-versus-comprehensive-neuropsychological-test-batteries-a-national-academy-of-neuropsychology-education-paper%C3%A2
#11
Tresa M Roebuck-Spencer, Tannahill Glen, Antonio E Puente, Robert L Denney, Ronald M Ruff, Gayle Hostetter, Kevin J Bianchini
The American Medical Association Current Procedural Panel developed a new billing code making behavioral health screening a reimbursable healthcare service. The use of computerized testing as a means for cognitive screening and brief cognitive testing is increasing at a rapid rate. The purpose of this education paper is to provide information to clinicians, healthcare administrators, and policy developers about the purpose, strengths, and limitations of cognitive screening tests versus comprehensive neuropsychological evaluations...
March 10, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28332285/early-detection-of-dementia-in-people-with-an-intellectual-disability-a-german-pilot-study
#12
Bettina Kuske, Christian Wolff, Uwe Gövert, Sandra Verena Müller
BACKGROUND: This study investigated the application of a newly developed neuropsychological assessment, the Wolfenbütteler Dementia Test for Individuals with Intellectual Disabilities (WDTIM) in combination with the Dementia Screening Questionnaire for Individuals with Intellectual Disabilities (DSQIID). METHODS: The instruments were evaluated in a prospective 2-year follow-up study. A total of 102 people with an intellectual disability were assessed at 6-month intervals...
March 23, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28332122/cognitive-impairments-and-predominant-polarity-in-bipolar-disorder-a-cross-sectional-study
#13
Gabriel Okawa Belizario, Alexandre Duarte Gigante, Cristiana Castanho de Almeida Rocca, Beny Lafer
BACKGROUND: Bipolar disorder (BD) patients exhibit cognitive impairments during euthymic states. Studies suggest that manic episodes may be correlated to cognitive impairments. The present study investigated the relationship between predominant polarity and the cognitive deficits frequently detected in bipolar patients. We hypothesize that mania predominant polarity (MPP) patients should exhibit greater cognitive impairments in comparison to depressive (DPP) and indefinite predominant polarity (IPP) patients and healthy control (HC) individuals...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28330962/distinct-white-matter-alterations-following-severe-stroke-longitudinal-dti-study-in-neglect
#14
Roza M Umarova, Lena Beume, Marco Reisert, Christoph P Kaller, Stefan Klöppel, Irina Mader, Volkmar Glauche, Valerij G Kiselev, Marco Catani, Cornelius Weiller
OBJECTIVE: To distinguish white matter remodeling directly induced by stroke lesion from that evoked by remote network dysfunction, using spatial neglect as a model. METHODS: We examined 24 visual neglect/extinction patients and 17 control patients combining comprehensive analyses of diffusion tensor metrics and global fiber tracking with neuropsychological testing in the acute (6.3 ± 0.5 days poststroke) and chronic (134 ± 7 days poststroke) stroke phases. RESULTS: Compared to stroke controls, patients with spatial neglect/extinction displayed longitudinal white matter alterations with 2 defining signatures: (1) perilesional degenerative changes characterized by congruently reduced fractional anisotropy and increased radial diffusivity (RD), axial diffusivity, and mean diffusivity, all suggestive of direct axonal damage by lesion and therefore nonspecific for impaired attention network and (2) transneuronal changes characterized by an increased RD in contralesional frontoparietal and bilateral occipital connections, suggestive of primary periaxonal involvement; these changes were distinctly related to the degree of unrecovered neglect symptoms in chronic stroke, hence emerging as network-specific alterations...
March 22, 2017: Neurology
https://www.readbyqxmd.com/read/28330539/-state-of-the-art-work-up-of-dementia-disorder
#15
Steen Gregers Hasselbalch
Early diagnosis of a dementia disorder is required for early support, treatment and information. A basic programme including history taking, somatic and neurological examination, blood screening and a structural scan will suffice in typical cases. For patients with uncertain or atypical symptoms or disease course, supplementary investigations are warranted, including biomarkers in cerebrospinal fluid, functional imaging and neuropsychological testing. Also, imaging of specific protein accumulations in Alzheimer's disease may serve to monitor disease progression and effects of interventions...
March 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28330458/the-effects-of-an-extensive-exercise-programme-on-the-progression-of-mild-cognitive-impairment-mci-study-protocol-for-a-randomised-controlled-trial
#16
Kate E Devenney, Brian Lawlor, Marcel G M Olde Rikkert, Stefan Schneider
BACKGROUND: Exercise interventions to prevent dementia and delay cognitive decline have gained considerable attention in recent years. Human and animal studies have demonstrated that regular physical activity targets brain function by increasing cognitive reserve. There is also evidence of structural changes caused by exercise in preventing or delaying the genesis of neurodegeneration. Although initial studies indicate enhanced cognitive performance in patients with mild cognitive impairment (MCI) following an exercise intervention, little is known about the effect of an extensive, controlled and regular exercise regimen on the neuropathology of patients with MCI...
March 22, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28329909/testing-the-boundaries-of-boundary-extension-anticipatory-scene-representation-across-development-and-disorder
#17
G Spanò, H Intraub, J O Edgin
Recent studies have suggested that Boundary Extension (BE), a scene construction error, may be linked to the function of the hippocampus. In this study, we tested BE in two groups with variations in hippocampal development and disorder: a typically developing sample ranging from preschool to adolescence and individuals with Down syndrome. We assessed BE across three different test modalities: drawing, visual recognition, and a 3D scene boundary reconstruction task. Despite confirmed fluctuations in memory function measured through a neuropsychological assessment, the results showed consistent BE in all groups across test modalities, confirming the near universal nature of BE...
March 22, 2017: Hippocampus
https://www.readbyqxmd.com/read/28329149/prediction-of-long-term-cognitive-decline-following-postoperative-delirium-in-older-adults
#18
Elizabeth E Devore, Tamara G Fong, Edward R Marcantonio, Eva M Schmitt, Thomas G Travison, Richard N Jones, Sharon K Inouye
Background: Increasing evidence suggests that postoperative delirium may result in long-term cognitive decline among older adults. Risk factors for such cognitive decline are unknown. Methods: We studied 126 older participants without delirium or dementia upon entering the Successful AGing After Elective Surgery (SAGES) study, who developed postoperative delirium and completed repeated cognitive assessments (up to 36 months of follow-up). Pre-surgical factors were assessed preoperatively and divided into nine groupings of related factors ("domains")...
March 15, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28329084/obstructive-sleep-apnea-is-associated-with-early-but-possibly-modifiable-alzheimer-s-disease-changes
#19
Claudio Liguori, Nicola Biagio Mercuri, Francesca Izzi, Andrea Romigi, Alberto Cordella, Giuseppe Sancesario, Fabio Placidi
Study Objectives: Obstructive sleep apnea (OSA) is a common sleep disorder. Actually, literature lacks studies examining sleep, cognition, and Alzheimer's Disease (AD) cerebrospinal-fluid biomarkers in OSA patients. Therefore, we firstly studied cognitive performances, polysomnographic sleep, and CSF β-amyloid, tau proteins and lactate levels in patients affected by subjective cognitive impairment (SCI) divided in three groups: OSA patients (showing an Apnea-Hypopnea Index - AHI ≥15/h), controls (showing an AHI<15/h), and patients treating OSA by continuous positive airway pressure (CPAP)...
January 28, 2017: Sleep
https://www.readbyqxmd.com/read/28329071/association-of-mild-obstructive-sleep-apnea-with-cognitive-performance-excessive-daytime-sleepiness-and-quality-of-life-in-the-general-population-the-korean-genome-and-epidemiology-study-koges
#20
Hyun Kim, Robert J Thomas, Chang-Ho Yun, Rhoda Au, Seung Ku Lee, Sunghee Lee, Chol Shin
Study Objectives: Research points to impaired cognitive performance in sleep clinic patients with obstructive sleep apnea (OSA). However, inconsistent findings from various epidemiologic studies make this relationship less generalizable. The current study investigated the association between OSA functional outcome measures, such as cognition, daytime sleepiness, and quality of life, in a Korean general population sample. Methods: A total of 1,492 participants from the Korean Genome and Epidemiology Study (KoGES) were included in the analyses...
January 28, 2017: Sleep
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